Mutagenetix > Incidental Mutation

Incidental Mutation 'R1466:Abca13'

201209

Institutional Source

Beutler Lab

Gene Symbol

Abca13

Ensembl Gene

ENSMUSG00000004668

Gene Name

ATP-binding cassette, sub-family A (ABC1), member 13

Synonyms

A930002G16Rik

Accession Numbers

NCBI RefSeq: NM_178259.3; MGI:2388707

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1466 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

9191942-9684259 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 9570536 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000040465 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000042740]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000042740

SMART Domains

Protein: ENSMUSP00000040465
Gene: ENSMUSG00000004668

Domain	Start	End	E-Value	Type
transmembrane domain	20	42	N/A	INTRINSIC
low complexity region	358	379	N/A	INTRINSIC
low complexity region	441	451	N/A	INTRINSIC
low complexity region	820	831	N/A	INTRINSIC
low complexity region	1382	1393	N/A	INTRINSIC
low complexity region	1721	1737	N/A	INTRINSIC
low complexity region	1859	1872	N/A	INTRINSIC
Pfam:ABC2_membrane_3	3288	3740	4.7e-21	PFAM
low complexity region	3796	3809	N/A	INTRINSIC
AAA	3835	4019	8.08e-12	SMART
transmembrane domain	4206	4228	N/A	INTRINSIC
Pfam:ABC2_membrane_3	4317	4646	1.6e-33	PFAM
AAA	4721	4909	8.86e-9	SMART

Coding Region Coverage

1x: 97.4%
3x: 96.7%
10x: 94.7%
20x: 90.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.[provided by RefSeq, Mar 2009]

Allele List at MGI

All alleles(3) : Targeted(3)

Other mutations in this stock

Total: 134 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110012J17Rik	T	A	17: 66,380,435	D492V	probably damaging	Het
Abcg8	G	C	17: 84,686,727		probably benign	Het
Abhd15	C	T	11: 77,515,410	A71V	probably damaging	Het
AC167973.1	A	T	9: 43,265,352		noncoding transcript	Het
Adamts12	T	C	15: 11,311,359	F1234S	probably benign	Het
Ahnak	A	G	19: 9,015,875	D4841G	probably damaging	Het
Akap13	T	C	7: 75,729,049	S2095P	possibly damaging	Het
Ampd2	T	C	3: 108,080,337		probably null	Het
Arhgef17	G	T	7: 100,929,659	P694Q	possibly damaging	Het
Arrdc1	T	C	2: 24,925,795	I398V	probably benign	Het
Ash1l	T	C	3: 89,052,065	Y2250H	probably damaging	Het
Aspg	A	G	12: 112,121,852	N385D	probably benign	Het
Atxn3	G	A	12: 101,926,499	R319C	possibly damaging	Het
BC005561	T	A	5: 104,518,257	I215N	probably damaging	Het
Brca2	G	A	5: 150,552,258	A2478T	probably damaging	Het
Btrc	T	A	19: 45,513,382		probably benign	Het
C1s1	C	T	6: 124,531,131	C633Y	probably damaging	Het
C8g	C	T	2: 25,500,216	A6T	probably benign	Het
Capza2	T	C	6: 17,657,159		probably benign	Het
Cbl	A	T	9: 44,154,244	V706E	probably benign	Het
Ccdc84	A	T	9: 44,413,680		probably benign	Het
Cfhr1	C	T	1: 139,557,574	E45K	probably benign	Het
Chd7	G	A	4: 8,840,561		probably null	Het
Chek1	G	T	9: 36,725,857	A2E	probably damaging	Het
Clcn2	G	A	16: 20,712,552		probably benign	Het
Cndp2	G	A	18: 84,677,315		probably benign	Het
Cntnap1	C	A	11: 101,180,360	F366L	probably damaging	Het
Col5a1	G	T	2: 28,003,846		probably benign	Het
Corin	C	T	5: 72,302,790		probably null	Het
Crb2	T	C	2: 37,783,388	Y99H	probably damaging	Het
Csf3r	T	A	4: 126,031,932		probably benign	Het
Ctdspl2	G	A	2: 122,003,929	R332K	probably benign	Het
Ctnnbl1	C	T	2: 157,799,417		probably benign	Het
Cym	G	A	3: 107,213,458	T277I	probably damaging	Het
Cyp2d11	C	T	15: 82,391,735	C215Y	probably benign	Het
Dido1	G	A	2: 180,662,328	P1261L	probably damaging	Het
Dnah10	T	A	5: 124,763,096	Y1265N	probably benign	Het
Dtx3l	G	A	16: 35,932,728	L503F	probably damaging	Het
Eda	T	A	X: 100,392,392		probably benign	Homo
Efhb	A	G	17: 53,437,178	F462L	probably damaging	Het
Enpep	T	A	3: 129,319,448	T203S	probably damaging	Het
Exd1	G	A	2: 119,520,734		probably benign	Het
Fam184b	G	A	5: 45,580,509		probably benign	Het
Fam20b	T	C	1: 156,686,188		probably benign	Het
Fat3	A	C	9: 16,375,482	V915G	probably damaging	Het
Fbln7	A	G	2: 128,877,429	T49A	probably benign	Het
Fcho1	C	T	8: 71,712,560	A418T	probably benign	Het
Fgf14	T	A	14: 124,676,539	K60M	probably benign	Het
Galnt4	A	G	10: 99,108,709	R99G	probably benign	Het
Gimap4	C	A	6: 48,691,282	Q196K	probably benign	Het
Glcci1	C	T	6: 8,537,964	T6I	probably damaging	Het
Gm10110	A	T	14: 89,898,075		noncoding transcript	Het
Gm4884	A	G	7: 41,043,128	K174E	probably damaging	Het
Gm6583	C	T	5: 112,354,764	G358D	probably benign	Het
Grip2	A	T	6: 91,788,443	D19E	probably damaging	Het
Grk4	T	C	5: 34,694,750	S113P	probably benign	Het
Hectd3	G	A	4: 116,996,566	E220K	probably damaging	Het
Helz2	G	A	2: 181,236,297	P903S	probably damaging	Het
Hydin	T	A	8: 110,532,953	V2519E	possibly damaging	Het
Igf2r	A	T	17: 12,717,269		probably benign	Het
Ints11	G	A	4: 155,888,110		probably null	Het
Kif1a	A	G	1: 93,054,929	W718R	possibly damaging	Het
Kif1b	A	T	4: 149,223,252	Y839N	probably damaging	Het
Kif20b	T	A	19: 34,950,599	V1047D	probably benign	Het
Klhl23	T	C	2: 69,833,888	I527T	probably damaging	Het
Klra10	T	A	6: 130,279,315	R125S	probably damaging	Het
Klra10	T	C	6: 130,279,431	N87D	probably damaging	Het
Lars	G	A	18: 42,210,050	R1101C	probably damaging	Het
Lcn4	G	A	2: 26,668,576	P166L	probably damaging	Het
Letmd1	T	A	15: 100,472,542		probably null	Het
Lrrc27	A	G	7: 139,230,308		probably benign	Het
Map4k2	G	T	19: 6,341,917	W87L	probably damaging	Het
Mccc1	A	G	3: 35,974,286	V457A	probably benign	Het
Mdn1	T	A	4: 32,730,788	S2886T	probably benign	Het
Mgat4a	A	T	1: 37,464,406		probably benign	Het
Mmp1b	A	T	9: 7,384,779		probably benign	Het
Mroh2b	G	T	15: 4,925,684	D720Y	probably damaging	Het
Mrpl24	T	A	3: 87,921,928	Y21*	probably null	Het
Mrps35	C	T	6: 147,055,984	T169M	probably damaging	Het
Muc2	A	G	7: 141,748,974	Y457C	probably damaging	Het
Muc4	G	A	16: 32,753,595	G1157D	probably benign	Het
Myg1	T	A	15: 102,337,390	L275Q	probably damaging	Het
Naga	T	A	15: 82,334,788	M237L	probably null	Het
Nek1	C	T	8: 61,125,136		probably benign	Het
Oc90	T	A	15: 65,897,720	Y96F	probably damaging	Het
Olfr1029	T	A	2: 85,975,995	F251I	probably damaging	Het
Olfr103	A	T	17: 37,336,956	L92H	probably benign	Het
Olfr1253	C	T	2: 89,752,267	C187Y	probably damaging	Het
Olfr46	A	G	7: 140,610,969	I268V	probably benign	Het
Olfr522	A	G	7: 140,162,203	V249A	probably damaging	Het
Orc4	A	T	2: 48,909,494	C324S	possibly damaging	Het
Pald1	T	C	10: 61,348,525		probably benign	Het
Paox	A	G	7: 140,129,281		probably benign	Het
Pcdh10	T	G	3: 45,379,974	L241R	probably damaging	Het
Pdzrn4	T	C	15: 92,770,537	S857P	probably benign	Het
Plec	C	T	15: 76,185,908	E1000K	possibly damaging	Het
Plvap	A	T	8: 71,508,481	V149D	probably benign	Het
Ppef1	C	A	X: 160,625,674		probably null	Homo
Prkaa1	C	A	15: 5,178,798	P507T	probably benign	Het
Psmd2	A	G	16: 20,657,965		probably benign	Het
Ptch1	A	G	13: 63,524,969	Y804H	probably benign	Het
R3hdm2	A	G	10: 127,476,690	I434V	probably benign	Het
Rbm28	G	A	6: 29,155,017		probably benign	Het
Rfx5	T	A	3: 94,956,303	Y88N	probably damaging	Het
Rnase2b	A	T	14: 51,162,839	K126*	probably null	Het
Rpl3l	A	G	17: 24,730,871	I15V	probably benign	Het
Saal1	G	T	7: 46,702,545		probably null	Het
Sbpl	A	C	17: 23,953,254	D230E	unknown	Het
Scn10a	T	C	9: 119,666,490	Y322C	probably damaging	Het
Sec16a	A	T	2: 26,431,157	Y1308N	probably damaging	Het
Sis	A	T	3: 72,932,060	D824E	possibly damaging	Het
Slc25a36	A	G	9: 97,080,355	F194L	probably damaging	Het
Slc27a4	T	A	2: 29,811,190	V331E	probably damaging	Het
Slc7a11	G	T	3: 50,381,073		probably null	Het
Slco4c1	A	T	1: 96,841,172	S322T	probably damaging	Het
Smarcc2	A	T	10: 128,474,245	T376S	probably damaging	Het
Srebf1	C	T	11: 60,200,702	R999H	probably benign	Het
St3gal3	A	C	4: 118,107,662	M1R	probably null	Het
Syp	A	T	X: 7,648,705		probably benign	Homo
Tas1r2	A	G	4: 139,669,411	D687G	probably damaging	Het
Tekt4	A	T	17: 25,472,074	Q118L	probably benign	Het
Tph2	T	C	10: 115,079,695	N480S	probably benign	Het
Tsc2	A	T	17: 24,608,973	M839K	probably damaging	Het
Ttc22	T	C	4: 106,622,780	F77S	probably damaging	Het
Uaca	C	T	9: 60,854,321	A205V	possibly damaging	Het
Ubp1	T	G	9: 113,944,835		probably benign	Het
Uhmk1	A	T	1: 170,208,653		probably null	Het
Usp17lc	A	G	7: 103,418,941	H481R	possibly damaging	Het
Vwa3a	A	G	7: 120,768,165	Y181C	probably damaging	Het
Wdr26	C	T	1: 181,185,934		probably benign	Het
Wfikkn2	G	A	11: 94,238,895	T140I	probably damaging	Het
Zfp704	G	T	3: 9,447,348	T288N	possibly damaging	Het
Zfp93	T	C	7: 24,276,096	V502A	probably damaging	Het
Zzef1	C	T	11: 72,924,679	P2942S	probably damaging	Het

Other mutations in Abca13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Abca13	APN	11	9297443	missense	probably benign	0.24
IGL00481:Abca13	APN	11	9290969	missense	probably damaging	0.99
IGL00707:Abca13	APN	11	9291586	missense	probably damaging	0.99
IGL00755:Abca13	APN	11	9542102	missense	possibly damaging	0.87
IGL00771:Abca13	APN	11	9290870	missense	probably damaging	1.00
IGL00802:Abca13	APN	11	9297717	missense	probably damaging	0.96
IGL00807:Abca13	APN	11	9378285	missense	probably benign	0.10
IGL00977:Abca13	APN	11	9399284	missense	probably damaging	1.00
IGL01064:Abca13	APN	11	9483855	missense	probably benign	0.01
IGL01100:Abca13	APN	11	9274673	splice site	probably null
IGL01290:Abca13	APN	11	9256232	missense	probably damaging	1.00
IGL01299:Abca13	APN	11	9298743	missense	probably benign	0.22
IGL01302:Abca13	APN	11	9399470	splice site	probably benign
IGL01307:Abca13	APN	11	9297159	missense	possibly damaging	0.86
IGL01349:Abca13	APN	11	9292076	missense	probably benign	0.05
IGL01351:Abca13	APN	11	9267565	missense	probably benign	0.28
IGL01446:Abca13	APN	11	9403834	missense	probably damaging	0.97
IGL01453:Abca13	APN	11	9403834	missense	probably damaging	0.97
IGL01461:Abca13	APN	11	9403834	missense	probably damaging	0.97
IGL01476:Abca13	APN	11	9403834	missense	probably damaging	0.97
IGL01506:Abca13	APN	11	9297447	missense	probably benign	0.36
IGL01527:Abca13	APN	11	9290788	missense	possibly damaging	0.49
IGL01559:Abca13	APN	11	9309020	missense	possibly damaging	0.82
IGL01580:Abca13	APN	11	9293527	missense	probably benign	0.00
IGL01679:Abca13	APN	11	9298071	missense	probably benign	0.07
IGL01731:Abca13	APN	11	9249749	splice site	probably benign
IGL01762:Abca13	APN	11	9315423	missense	probably benign	0.18
IGL01781:Abca13	APN	11	9399280	missense	probably damaging	1.00
IGL01802:Abca13	APN	11	9292438	missense	probably benign	0.00
IGL01809:Abca13	APN	11	9290339	missense	probably damaging	0.96
IGL01906:Abca13	APN	11	9216225	missense	probably damaging	1.00
IGL01928:Abca13	APN	11	9683342	missense	probably benign	0.13
IGL01940:Abca13	APN	11	9567661	splice site	probably benign
IGL01993:Abca13	APN	11	9258452	unclassified	probably benign
IGL02039:Abca13	APN	11	9297193	nonsense	probably null
IGL02159:Abca13	APN	11	9314545	missense	probably benign	0.00
IGL02202:Abca13	APN	11	9288529	missense	possibly damaging	0.55
IGL02268:Abca13	APN	11	9290626	missense	probably benign	0.00
IGL02332:Abca13	APN	11	9291482	missense	probably damaging	0.98
IGL02380:Abca13	APN	11	9291599	missense	possibly damaging	0.73
IGL02466:Abca13	APN	11	9297527	missense	probably benign	0.00
IGL02505:Abca13	APN	11	9581498	missense	probably damaging	1.00
IGL02507:Abca13	APN	11	9399388	missense	probably damaging	1.00
IGL02558:Abca13	APN	11	9399387	missense	probably damaging	1.00
IGL02581:Abca13	APN	11	9399132	splice site	probably benign
IGL02586:Abca13	APN	11	9293983	missense	possibly damaging	0.56
IGL02598:Abca13	APN	11	9431898	missense	probably damaging	1.00
IGL02747:Abca13	APN	11	9373282	nonsense	probably null
IGL02893:Abca13	APN	11	9290543	missense	probably damaging	0.96
IGL02930:Abca13	APN	11	9378226	missense	possibly damaging	0.86
IGL02967:Abca13	APN	11	9378291	missense	probably damaging	0.99
IGL02983:Abca13	APN	11	9290663	missense	probably benign	0.40
IGL02999:Abca13	APN	11	9581757	splice site	probably benign
IGL03100:Abca13	APN	11	9258527	missense	probably benign	0.25
IGL03114:Abca13	APN	11	9528999	missense	probably benign	0.06
IGL03230:Abca13	APN	11	9294313	missense	probably benign	0.02
IGL03329:Abca13	APN	11	9298047	missense	probably benign	0.08
IGL03380:Abca13	APN	11	9298574	missense	probably benign	0.10
IGL02835:Abca13	UTSW	11	9451515	missense	probably damaging	1.00
PIT4366001:Abca13	UTSW	11	9294962	missense	probably benign
PIT4458001:Abca13	UTSW	11	9298304	missense	probably benign	0.05
R0017:Abca13	UTSW	11	9292775	missense	probably damaging	0.99
R0079:Abca13	UTSW	11	9293493	missense	probably benign	0.00
R0089:Abca13	UTSW	11	9292886	missense	possibly damaging	0.76
R0103:Abca13	UTSW	11	9273951	missense	probably damaging	1.00
R0103:Abca13	UTSW	11	9273951	missense	probably damaging	1.00
R0113:Abca13	UTSW	11	9292114	missense	possibly damaging	0.54
R0119:Abca13	UTSW	11	9298076	missense	probably benign	0.03
R0152:Abca13	UTSW	11	9581724	missense	probably damaging	0.98
R0255:Abca13	UTSW	11	9581545	missense	probably damaging	1.00
R0277:Abca13	UTSW	11	9294701	missense	probably benign	0.25
R0278:Abca13	UTSW	11	9378215	missense	probably damaging	1.00
R0294:Abca13	UTSW	11	9269122	splice site	probably null
R0299:Abca13	UTSW	11	9298076	missense	probably benign	0.03
R0310:Abca13	UTSW	11	9293810	missense	probably benign	0.36
R0317:Abca13	UTSW	11	9293459	missense	probably damaging	1.00
R0323:Abca13	UTSW	11	9294701	missense	probably benign	0.25
R0324:Abca13	UTSW	11	9297669	missense	possibly damaging	0.76
R0329:Abca13	UTSW	11	9399430	missense	probably damaging	0.97
R0336:Abca13	UTSW	11	9298481	missense	probably benign	0.04
R0346:Abca13	UTSW	11	9566278	missense	probably damaging	0.99
R0380:Abca13	UTSW	11	9588500	splice site	probably null
R0382:Abca13	UTSW	11	9636650	splice site	probably benign
R0482:Abca13	UTSW	11	9328207	missense	possibly damaging	0.88
R0487:Abca13	UTSW	11	9331687	missense	probably benign	0.07
R0491:Abca13	UTSW	11	9298235	missense	probably benign	0.02
R0496:Abca13	UTSW	11	9291701	missense	probably benign	0.01
R0505:Abca13	UTSW	11	9291058	missense	probably benign	0.00
R0511:Abca13	UTSW	11	9294559	missense	probably benign
R0525:Abca13	UTSW	11	9293371	missense	probably damaging	1.00
R0538:Abca13	UTSW	11	9267622	critical splice donor site	probably null
R0615:Abca13	UTSW	11	9256197	missense	probably damaging	0.96
R0634:Abca13	UTSW	11	9314491	missense	possibly damaging	0.59
R0699:Abca13	UTSW	11	9588508	splice site	probably benign
R0848:Abca13	UTSW	11	9682011	nonsense	probably null
R0883:Abca13	UTSW	11	9291238	nonsense	probably null
R0892:Abca13	UTSW	11	9298305	missense	probably benign	0.00
R0904:Abca13	UTSW	11	9298740	missense	probably benign	0.22
R0968:Abca13	UTSW	11	9298016	missense	probably benign	0.00
R1187:Abca13	UTSW	11	9528981	missense	probably benign	0.00
R1299:Abca13	UTSW	11	9294821	missense	possibly damaging	0.94
R1323:Abca13	UTSW	11	9290937	missense	possibly damaging	0.86
R1323:Abca13	UTSW	11	9290937	missense	possibly damaging	0.86
R1368:Abca13	UTSW	11	9291836	missense	probably benign
R1387:Abca13	UTSW	11	9682085	nonsense	probably null
R1436:Abca13	UTSW	11	9292646	missense	probably damaging	0.99
R1449:Abca13	UTSW	11	9298580	missense	probably damaging	1.00
R1450:Abca13	UTSW	11	9430531	splice site	probably benign
R1462:Abca13	UTSW	11	9483924	splice site	probably benign
R1465:Abca13	UTSW	11	9399303	missense	probably damaging	1.00
R1465:Abca13	UTSW	11	9399303	missense	probably damaging	1.00
R1494:Abca13	UTSW	11	9466429	nonsense	probably null
R1559:Abca13	UTSW	11	9399180	missense	probably null	1.00
R1564:Abca13	UTSW	11	9434316	nonsense	probably null
R1698:Abca13	UTSW	11	9314507	missense	probably benign	0.13
R1728:Abca13	UTSW	11	9249680	missense	probably benign	0.02
R1734:Abca13	UTSW	11	9585460	missense	probably benign	0.03
R1781:Abca13	UTSW	11	9269194	missense	probably damaging	1.00
R1782:Abca13	UTSW	11	9297971	missense	probably benign	0.36
R1807:Abca13	UTSW	11	9291755	missense	probably damaging	0.98
R1830:Abca13	UTSW	11	9290350	missense	probably benign	0.04
R1869:Abca13	UTSW	11	9292134	missense	probably benign	0.19
R1870:Abca13	UTSW	11	9292134	missense	probably benign	0.19
R1871:Abca13	UTSW	11	9292134	missense	probably benign	0.19
R1903:Abca13	UTSW	11	9466411	missense	probably benign	0.13
R1916:Abca13	UTSW	11	9534456	missense	probably damaging	1.00
R1936:Abca13	UTSW	11	9293595	missense	probably benign	0.13
R1976:Abca13	UTSW	11	9397815	missense	probably damaging	1.00
R2001:Abca13	UTSW	11	9273967	missense	probably benign	0.01
R2007:Abca13	UTSW	11	9191987	missense	probably benign	0.19
R2016:Abca13	UTSW	11	9290619	missense	probably damaging	1.00
R2017:Abca13	UTSW	11	9290619	missense	probably damaging	1.00
R2034:Abca13	UTSW	11	9292628	missense	possibly damaging	0.83
R2051:Abca13	UTSW	11	9328098	missense	probably benign	0.04
R2075:Abca13	UTSW	11	9522382	missense	probably damaging	1.00
R2118:Abca13	UTSW	11	9309013	splice site	probably benign
R2120:Abca13	UTSW	11	9309013	splice site	probably benign
R2124:Abca13	UTSW	11	9309013	splice site	probably benign
R2148:Abca13	UTSW	11	9615764	missense	probably damaging	1.00
R2149:Abca13	UTSW	11	9267508	missense	possibly damaging	0.68
R2157:Abca13	UTSW	11	9577170	missense	probably damaging	0.97
R2167:Abca13	UTSW	11	9288532	missense	probably benign	0.19
R2261:Abca13	UTSW	11	9292288	missense	probably benign
R2263:Abca13	UTSW	11	9274702	missense	probably benign	0.04
R2281:Abca13	UTSW	11	9328136	missense	probably damaging	0.98
R2340:Abca13	UTSW	11	9399165	missense	probably damaging	0.99
R2357:Abca13	UTSW	11	9297336	missense	probably damaging	1.00
R2370:Abca13	UTSW	11	9256185	missense	possibly damaging	0.85
R2384:Abca13	UTSW	11	9267450	splice site	probably benign
R2393:Abca13	UTSW	11	9275057	nonsense	probably null
R2432:Abca13	UTSW	11	9451333	splice site	probably benign
R2446:Abca13	UTSW	11	9275101	missense	probably benign
R2568:Abca13	UTSW	11	9333310	missense	probably benign	0.40
R2847:Abca13	UTSW	11	9294584	missense	possibly damaging	0.59
R2860:Abca13	UTSW	11	9309057	missense	probably damaging	0.99
R2861:Abca13	UTSW	11	9309057	missense	probably damaging	0.99
R2862:Abca13	UTSW	11	9309057	missense	probably damaging	0.99
R2877:Abca13	UTSW	11	9291889	missense	possibly damaging	0.91
R2878:Abca13	UTSW	11	9291889	missense	possibly damaging	0.91
R3748:Abca13	UTSW	11	9316119	splice site	probably benign
R3789:Abca13	UTSW	11	9510668	missense	probably damaging	0.97
R3933:Abca13	UTSW	11	9354856	missense	probably damaging	1.00
R3981:Abca13	UTSW	11	9532407	missense	probably benign
R4002:Abca13	UTSW	11	9585415	missense	probably benign	0.00
R4010:Abca13	UTSW	11	9622013	splice site	probably benign
R4011:Abca13	UTSW	11	9622013	splice site	probably benign
R4127:Abca13	UTSW	11	9191973	missense	probably benign	0.00
R4214:Abca13	UTSW	11	9293877	missense	probably damaging	0.96
R4236:Abca13	UTSW	11	9256205	missense	probably damaging	1.00
R4237:Abca13	UTSW	11	9434188	missense	probably benign	0.01
R4359:Abca13	UTSW	11	9297629	missense	probably benign	0.02
R4378:Abca13	UTSW	11	9293644	missense	probably benign	0.00
R4389:Abca13	UTSW	11	9297878	missense	probably damaging	0.98
R4392:Abca13	UTSW	11	9309034	missense	possibly damaging	0.94
R4623:Abca13	UTSW	11	9309130	missense	probably damaging	1.00
R4684:Abca13	UTSW	11	9434193	nonsense	probably null
R4691:Abca13	UTSW	11	9434195	missense	probably damaging	1.00
R4700:Abca13	UTSW	11	9292306	missense	possibly damaging	0.59
R4701:Abca13	UTSW	11	9292306	missense	possibly damaging	0.59
R4704:Abca13	UTSW	11	9276990	missense	possibly damaging	0.94
R4751:Abca13	UTSW	11	9277973	critical splice donor site	probably null
R4772:Abca13	UTSW	11	9315339	splice site	probably null
R4782:Abca13	UTSW	11	9328096	missense	probably damaging	0.96
R4801:Abca13	UTSW	11	9522341	missense	possibly damaging	0.94
R4802:Abca13	UTSW	11	9522341	missense	possibly damaging	0.94
R4819:Abca13	UTSW	11	9290421	missense	possibly damaging	0.88
R4831:Abca13	UTSW	11	9542077	nonsense	probably null
R4851:Abca13	UTSW	11	9483890	missense	probably benign	0.02
R4857:Abca13	UTSW	11	9294143	missense	probably benign	0.22
R4869:Abca13	UTSW	11	9315434	splice site	probably null
R4982:Abca13	UTSW	11	9292348	missense	possibly damaging	0.58
R5031:Abca13	UTSW	11	9297678	missense	probably damaging	0.99
R5044:Abca13	UTSW	11	9373323	missense	possibly damaging	0.80
R5092:Abca13	UTSW	11	9258535	missense	probably damaging	1.00
R5155:Abca13	UTSW	11	9532447	missense	probably damaging	0.98
R5173:Abca13	UTSW	11	9682032	frame shift	probably null
R5180:Abca13	UTSW	11	9466510	missense	probably benign	0.01
R5244:Abca13	UTSW	11	9275081	missense	probably benign	0.28
R5257:Abca13	UTSW	11	9249684	missense	possibly damaging	0.94
R5258:Abca13	UTSW	11	9249684	missense	possibly damaging	0.94
R5299:Abca13	UTSW	11	9431861	missense	probably damaging	1.00
R5363:Abca13	UTSW	11	9277035	missense	possibly damaging	0.75
R5365:Abca13	UTSW	11	9628629	missense	probably damaging	1.00
R5419:Abca13	UTSW	11	9193533	critical splice donor site	probably null
R5426:Abca13	UTSW	11	9290722	missense	probably damaging	1.00
R5468:Abca13	UTSW	11	9294062	missense	probably damaging	1.00
R5477:Abca13	UTSW	11	9301298	missense	possibly damaging	0.49
R5541:Abca13	UTSW	11	9291545	missense	probably benign	0.00
R5553:Abca13	UTSW	11	9328158	missense	probably damaging	1.00
R5556:Abca13	UTSW	11	9258546	missense	possibly damaging	0.91
R5566:Abca13	UTSW	11	9294615	nonsense	probably null
R5582:Abca13	UTSW	11	9636639	splice site	probably null
R5604:Abca13	UTSW	11	9566279	missense	probably damaging	0.97
R5609:Abca13	UTSW	11	9403874	missense	probably benign	0.01
R5617:Abca13	UTSW	11	9277891	missense	probably benign	0.00
R5693:Abca13	UTSW	11	9316233	missense	probably benign	0.29
R5707:Abca13	UTSW	11	9510620	missense	probably damaging	1.00
R5725:Abca13	UTSW	11	9577181	missense	probably benign	0.00
R5728:Abca13	UTSW	11	9570576	missense	probably damaging	1.00
R5738:Abca13	UTSW	11	9621917	missense	probably damaging	1.00
R5758:Abca13	UTSW	11	9314536	missense	probably damaging	0.97
R5762:Abca13	UTSW	11	9581665	missense	probably damaging	1.00
R5771:Abca13	UTSW	11	9291411	missense	probably damaging	1.00
R5809:Abca13	UTSW	11	9293692	missense	probably damaging	1.00
R5826:Abca13	UTSW	11	9682056	missense	probably damaging	0.99
R5831:Abca13	UTSW	11	9567777	nonsense	probably null
R5834:Abca13	UTSW	11	9277974	critical splice donor site	probably null
R5902:Abca13	UTSW	11	9297177	missense	probably damaging	1.00
R5933:Abca13	UTSW	11	9249658	missense	possibly damaging	0.63
R5945:Abca13	UTSW	11	9293398	missense	probably benign	0.04
R5969:Abca13	UTSW	11	9292214	nonsense	probably null
R5985:Abca13	UTSW	11	9291628	missense	probably benign	0.02
R5998:Abca13	UTSW	11	9567708	missense	probably damaging	0.97
R6021:Abca13	UTSW	11	9290465	nonsense	probably null
R6022:Abca13	UTSW	11	9290759	missense	probably damaging	1.00
R6032:Abca13	UTSW	11	9297752	missense	possibly damaging	0.52
R6032:Abca13	UTSW	11	9297752	missense	possibly damaging	0.52
R6105:Abca13	UTSW	11	9397812	missense	probably damaging	1.00
R6153:Abca13	UTSW	11	9301259	critical splice acceptor site	probably null
R6162:Abca13	UTSW	11	9309047	missense	probably damaging	1.00
R6187:Abca13	UTSW	11	9309085	missense	probably damaging	1.00
R6247:Abca13	UTSW	11	9403874	missense	probably benign	0.01
R6329:Abca13	UTSW	11	9277937	missense	probably damaging	1.00
R6352:Abca13	UTSW	11	9309139	splice site	probably null
R6367:Abca13	UTSW	11	9216248	missense	possibly damaging	0.85
R6423:Abca13	UTSW	11	9298778	missense	probably benign	0.01
R6424:Abca13	UTSW	11	9510542	missense	probably benign
R6456:Abca13	UTSW	11	9290474	missense	possibly damaging	0.94
R6490:Abca13	UTSW	11	9298661	missense	probably benign	0.00
R6547:Abca13	UTSW	11	9274757	missense	probably benign	0.04
R6594:Abca13	UTSW	11	9294632	missense	possibly damaging	0.52
R6604:Abca13	UTSW	11	9378384	missense	probably damaging	1.00
R6614:Abca13	UTSW	11	9294371	missense	probably benign	0.04
R6736:Abca13	UTSW	11	9465058	missense	probably damaging	1.00
R6742:Abca13	UTSW	11	9328168	missense	probably damaging	1.00
R6791:Abca13	UTSW	11	9378504	missense	probably damaging	1.00
R6834:Abca13	UTSW	11	9275110	missense	possibly damaging	0.48
R6936:Abca13	UTSW	11	9298568	missense	probably damaging	0.96
R6955:Abca13	UTSW	11	9294307	missense	probably benign	0.28
R7031:Abca13	UTSW	11	9621892	missense	probably damaging	1.00
R7065:Abca13	UTSW	11	9292595	missense	probably benign	0.02
R7067:Abca13	UTSW	11	9291845	missense	probably benign	0.14
R7070:Abca13	UTSW	11	9290701	missense	probably benign	0.06
R7094:Abca13	UTSW	11	9298610	missense	probably damaging	0.96
R7102:Abca13	UTSW	11	9335215	missense	probably damaging	1.00
R7105:Abca13	UTSW	11	9397842	missense	probably damaging	1.00
R7131:Abca13	UTSW	11	9291893	missense	probably benign	0.37
R7155:Abca13	UTSW	11	9529010	missense	probably benign
R7158:Abca13	UTSW	11	9273982	missense	probably benign
R7212:Abca13	UTSW	11	9298854	missense	probably benign	0.04
R7215:Abca13	UTSW	11	9288405	splice site	probably null
R7228:Abca13	UTSW	11	9297653	missense	probably benign
R7231:Abca13	UTSW	11	9294175	missense	probably benign	0.25
R7247:Abca13	UTSW	11	9290732	missense	probably benign	0.00
R7278:Abca13	UTSW	11	9291126	missense	possibly damaging	0.56
R7299:Abca13	UTSW	11	9294649	missense	probably damaging	0.98
R7304:Abca13	UTSW	11	9297203	missense	probably benign
R7328:Abca13	UTSW	11	9291545	missense	probably benign	0.14
R7374:Abca13	UTSW	11	9292136	missense	possibly damaging	0.46
R7376:Abca13	UTSW	11	9291118	missense	probably benign	0.00
R7384:Abca13	UTSW	11	9333257	missense	probably damaging	1.00
R7395:Abca13	UTSW	11	9291658	missense	probably benign	0.01
R7419:Abca13	UTSW	11	9276959	missense	probably damaging	1.00
R7419:Abca13	UTSW	11	9297833	missense	probably damaging	1.00
R7421:Abca13	UTSW	11	9510463	missense	probably benign
R7458:Abca13	UTSW	11	9290777	missense	possibly damaging	0.94
R7474:Abca13	UTSW	11	9328088	nonsense	probably null
R7492:Abca13	UTSW	11	9293167	missense	probably benign	0.08
R7660:Abca13	UTSW	11	9290678	missense	probably benign	0.00
R7677:Abca13	UTSW	11	9298349	nonsense	probably null
R7744:Abca13	UTSW	11	9290421	missense	possibly damaging	0.88
R7790:Abca13	UTSW	11	9297915	missense	probably damaging	1.00
R7798:Abca13	UTSW	11	9291664	missense	probably benign	0.04
R7811:Abca13	UTSW	11	9577141	splice site	probably null
R7831:Abca13	UTSW	11	9297404	missense	possibly damaging	0.46
R7867:Abca13	UTSW	11	9262139	critical splice donor site	probably null
R7910:Abca13	UTSW	11	9581590	missense	probably damaging	1.00
R7964:Abca13	UTSW	11	9316146	missense	probably benign	0.06
R8037:Abca13	UTSW	11	9293904	missense	probably damaging	1.00
R8049:Abca13	UTSW	11	9291867	missense	probably damaging	0.99
R8059:Abca13	UTSW	11	9373279	missense	probably benign	0.00
R8072:Abca13	UTSW	11	9294574	missense	probably benign	0.10
R8078:Abca13	UTSW	11	9301279	missense	probably benign	0.32
R8112:Abca13	UTSW	11	9314624	missense	probably benign	0.01
R8146:Abca13	UTSW	11	9397829	missense	probably damaging	1.00
R8164:Abca13	UTSW	11	9615799	missense	probably damaging	1.00
R8195:Abca13	UTSW	11	9274735	missense	probably benign	0.00
R8220:Abca13	UTSW	11	9434299	missense	possibly damaging	0.58
R8235:Abca13	UTSW	11	9262077	missense	probably damaging	0.99
R8307:Abca13	UTSW	11	9277922	nonsense	probably null
R8310:Abca13	UTSW	11	9378269	missense	possibly damaging	0.90
R8315:Abca13	UTSW	11	9378460	missense	probably null	1.00
R8315:Abca13	UTSW	11	9585502	missense	probably benign	0.44
R8324:Abca13	UTSW	11	9290395	missense	probably damaging	1.00
R8375:Abca13	UTSW	11	9315416	missense	probably benign	0.00
R8375:Abca13	UTSW	11	9397841	missense	probably damaging	1.00
R8400:Abca13	UTSW	11	9293925	missense	probably benign	0.00
R8400:Abca13	UTSW	11	9298218	missense	probably damaging	0.97
R8425:Abca13	UTSW	11	9314623	missense	possibly damaging	0.92
R8486:Abca13	UTSW	11	9275092	missense	probably benign	0.00
R8493:Abca13	UTSW	11	9510668	missense	probably damaging	0.97
R8502:Abca13	UTSW	11	9269282	missense	probably benign	0.02
R8716:Abca13	UTSW	11	9293774	missense	probably benign	0.09
R8787:Abca13	UTSW	11	9275053	missense	possibly damaging	0.92
R8829:Abca13	UTSW	11	9621881	missense	probably damaging	1.00
R8859:Abca13	UTSW	11	9378397	missense
R8871:Abca13	UTSW	11	9298071	missense	probably benign	0.07
R8883:Abca13	UTSW	11	9333168	missense	probably benign	0.00
R8919:Abca13	UTSW	11	9291653	missense	possibly damaging	0.84
R8966:Abca13	UTSW	11	9628588	missense	probably damaging	1.00
R8967:Abca13	UTSW	11	9292696	missense	probably benign	0.18
R8969:Abca13	UTSW	11	9277944	missense	probably benign
R8972:Abca13	UTSW	11	9328138	missense	probably damaging	1.00
R9002:Abca13	UTSW	11	9291926	missense	possibly damaging	0.94
R9046:Abca13	UTSW	11	9293525	missense	probably benign	0.04
R9051:Abca13	UTSW	11	9335232	missense	probably damaging	1.00
R9056:Abca13	UTSW	11	9464921	missense	probably damaging	1.00
R9061:Abca13	UTSW	11	9277847	missense	probably benign	0.02
R9072:Abca13	UTSW	11	9290834	missense	possibly damaging	0.93
R9090:Abca13	UTSW	11	9291698	missense	probably damaging	0.98
R9127:Abca13	UTSW	11	9292080	missense	probably benign	0.03
R9164:Abca13	UTSW	11	9328157	missense	probably damaging	1.00
R9175:Abca13	UTSW	11	9581593	missense	probably damaging	0.98
R9190:Abca13	UTSW	11	9291886	missense	probably damaging	0.96
R9244:Abca13	UTSW	11	9291577	missense	probably benign	0.01
R9255:Abca13	UTSW	11	9328213	missense	probably damaging	1.00
R9271:Abca13	UTSW	11	9291698	missense	probably damaging	0.98
R9321:Abca13	UTSW	11	9510475	missense	probably benign	0.00
R9356:Abca13	UTSW	11	9256305	missense	probably benign	0.11
R9369:Abca13	UTSW	11	9378444	missense	probably damaging	1.00
R9423:Abca13	UTSW	11	9290395	missense	probably damaging	1.00
R9432:Abca13	UTSW	11	9294559	missense	probably benign	0.00
R9455:Abca13	UTSW	11	9403897	missense	probably damaging	1.00
R9486:Abca13	UTSW	11	9290621	missense	possibly damaging	0.88
R9492:Abca13	UTSW	11	9293667	nonsense	probably null
R9511:Abca13	UTSW	11	9328130	missense	probably benign	0.16
R9545:Abca13	UTSW	11	9466538	missense	probably damaging	1.00
R9566:Abca13	UTSW	11	9464927	missense	probably damaging	1.00
R9609:Abca13	UTSW	11	9258549	missense	probably damaging	1.00
R9616:Abca13	UTSW	11	9290501	missense	probably benign	0.00
R9651:Abca13	UTSW	11	9293741	missense	probably benign	0.31
R9651:Abca13	UTSW	11	9585484	missense	probably benign
R9653:Abca13	UTSW	11	9293741	missense	probably benign	0.31
R9657:Abca13	UTSW	11	9293379	missense	probably benign	0.35
R9684:Abca13	UTSW	11	9333307	missense	probably damaging	1.00
X0013:Abca13	UTSW	11	9273899	missense	probably benign	0.02
X0057:Abca13	UTSW	11	9294744	missense	probably damaging	0.96
X0066:Abca13	UTSW	11	9267565	missense	probably damaging	0.96
Z1088:Abca13	UTSW	11	9294687	missense	probably damaging	0.99
Z1176:Abca13	UTSW	11	9251376	missense	possibly damaging	0.88
Z1176:Abca13	UTSW	11	9267461	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9294342	missense	probably benign	0.01
Z1176:Abca13	UTSW	11	9335181	missense	probably damaging	1.00
Z1176:Abca13	UTSW	11	9335182	missense	probably damaging	1.00
Z1177:Abca13	UTSW	11	9314545	frame shift	probably null

Predicted Primers

Posted On

2014-05-23