Incidental Mutation 'R1789:Myo10'
| ID |
201665 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo10
|
| Ensembl Gene |
ENSMUSG00000022272 |
| Gene Name |
myosin X |
| Synonyms |
myosin-X, D15Ertd600e |
| MMRRC Submission |
039820-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1789 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
25622636-25813759 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to G
at 25726611 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118280
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000110457]
[ENSMUST00000137601]
|
| AlphaFold |
F8VQB6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000110457
|
| SMART Domains |
Protein: ENSMUSP00000106087
Gene: ENSMUSG00000022272
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
57 |
740 |
N/A |
SMART |
|
IQ
|
741 |
763 |
1.27e-3 |
SMART |
|
IQ
|
764 |
786 |
1.06e0 |
SMART |
|
IQ
|
787 |
809 |
7.07e-2 |
SMART |
|
Pfam:MYO10_CC
|
881 |
932 |
4.2e-22 |
PFAM |
|
low complexity region
|
959 |
981 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1147 |
1165 |
N/A |
INTRINSIC |
|
PH
|
1217 |
1316 |
1.39e-21 |
SMART |
|
PH
|
1397 |
1503 |
6.76e-11 |
SMART |
|
MyTH4
|
1551 |
1699 |
4.12e-37 |
SMART |
|
B41
|
1700 |
1962 |
1.72e-44 |
SMART |
|
low complexity region
|
2050 |
2062 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126076
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130517
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000137601
|
| SMART Domains |
Protein: ENSMUSP00000118280
Gene: ENSMUSG00000022272
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
24 |
707 |
N/A |
SMART |
|
IQ
|
708 |
730 |
1.27e-3 |
SMART |
|
IQ
|
731 |
753 |
1.06e0 |
SMART |
|
IQ
|
754 |
776 |
7.07e-2 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011]
PHENOTYPE: Homozygous null mutations are semi-lethal with over half of homozygous embryos exhibiting exencephaly. Surviving mutants show decreased body weight, white spotting, syndactyly, persistence of hyaloid vascular system and other eye defects. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
G |
A |
16: 20,184,701 (GRCm39) |
P986L |
probably damaging |
Het |
| Acad10 |
A |
T |
5: 121,769,456 (GRCm39) |
Y667N |
possibly damaging |
Het |
| Ahi1 |
G |
A |
10: 20,839,014 (GRCm39) |
G121D |
probably benign |
Het |
| Ampd1 |
T |
A |
3: 103,006,442 (GRCm39) |
I690N |
possibly damaging |
Het |
| Amy1 |
C |
A |
3: 113,351,814 (GRCm39) |
W425L |
possibly damaging |
Het |
| Arhgap27 |
A |
T |
11: 103,223,831 (GRCm39) |
V823E |
probably damaging |
Het |
| Arhgef17 |
A |
G |
7: 100,579,077 (GRCm39) |
S624P |
probably damaging |
Het |
| Arid5b |
T |
C |
10: 68,021,897 (GRCm39) |
H231R |
probably damaging |
Het |
| Aspscr1 |
C |
A |
11: 120,579,386 (GRCm39) |
T78N |
probably damaging |
Het |
| Auts2 |
T |
A |
5: 131,501,288 (GRCm39) |
T42S |
probably damaging |
Het |
| Ccdc171 |
A |
G |
4: 83,473,045 (GRCm39) |
D158G |
probably damaging |
Het |
| Ces4a |
G |
A |
8: 105,864,729 (GRCm39) |
G69S |
probably damaging |
Het |
| Cfap61 |
T |
C |
2: 145,781,913 (GRCm39) |
|
probably null |
Het |
| Chrna5 |
T |
C |
9: 54,911,935 (GRCm39) |
V245A |
possibly damaging |
Het |
| Cntnap5c |
G |
A |
17: 58,320,916 (GRCm39) |
G163R |
probably damaging |
Het |
| Col5a2 |
A |
G |
1: 45,417,465 (GRCm39) |
|
probably null |
Het |
| Col5a2 |
T |
C |
1: 45,433,936 (GRCm39) |
Q759R |
probably damaging |
Het |
| Comp |
A |
G |
8: 70,829,796 (GRCm39) |
D340G |
probably benign |
Het |
| Cyfip1 |
T |
A |
7: 55,576,143 (GRCm39) |
D1104E |
probably damaging |
Het |
| Dnah11 |
A |
T |
12: 118,002,515 (GRCm39) |
S308T |
probably damaging |
Het |
| Dnah5 |
A |
G |
15: 28,270,572 (GRCm39) |
H958R |
probably benign |
Het |
| Elp3 |
A |
G |
14: 65,785,368 (GRCm39) |
Y478H |
probably damaging |
Het |
| Fam237b |
A |
T |
5: 5,625,652 (GRCm39) |
Q116L |
possibly damaging |
Het |
| Fat3 |
T |
C |
9: 16,288,281 (GRCm39) |
Y414C |
probably benign |
Het |
| Fbxo10 |
C |
A |
4: 45,046,389 (GRCm39) |
A574S |
probably damaging |
Het |
| Fsip2 |
G |
T |
2: 82,807,906 (GRCm39) |
L1408F |
probably benign |
Het |
| Fubp3 |
T |
C |
2: 31,501,747 (GRCm39) |
V425A |
possibly damaging |
Het |
| Gm7168 |
A |
T |
17: 14,169,846 (GRCm39) |
R404S |
probably benign |
Het |
| Gpd1 |
T |
G |
15: 99,621,083 (GRCm39) |
F299C |
probably damaging |
Het |
| Gpr137 |
C |
T |
19: 6,919,425 (GRCm39) |
|
probably benign |
Het |
| Grin3b |
T |
C |
10: 79,809,242 (GRCm39) |
S331P |
probably benign |
Het |
| Grk3 |
T |
A |
5: 113,089,584 (GRCm39) |
I281F |
probably damaging |
Het |
| Hoxb7 |
T |
A |
11: 96,177,607 (GRCm39) |
S18R |
probably damaging |
Het |
| Igf1r |
C |
T |
7: 67,864,681 (GRCm39) |
R1160* |
probably null |
Het |
| Itfg1 |
A |
G |
8: 86,452,141 (GRCm39) |
|
probably null |
Het |
| Itgb8 |
T |
C |
12: 119,166,190 (GRCm39) |
I114V |
probably benign |
Het |
| Kcnk1 |
A |
G |
8: 126,752,123 (GRCm39) |
E243G |
possibly damaging |
Het |
| Kif27 |
A |
G |
13: 58,491,822 (GRCm39) |
L439P |
probably damaging |
Het |
| Kif2c |
T |
A |
4: 117,024,558 (GRCm39) |
Q279L |
probably benign |
Het |
| Kmt2d |
A |
T |
15: 98,749,955 (GRCm39) |
|
probably benign |
Het |
| L3mbtl1 |
A |
G |
2: 162,816,422 (GRCm39) |
T821A |
probably benign |
Het |
| Lrrc24 |
A |
T |
15: 76,606,778 (GRCm39) |
M206K |
probably benign |
Het |
| Mamdc4 |
T |
G |
2: 25,457,634 (GRCm39) |
K460Q |
possibly damaging |
Het |
| Maml2 |
C |
G |
9: 13,608,641 (GRCm39) |
L30V |
probably damaging |
Het |
| Mc5r |
C |
G |
18: 68,471,741 (GRCm39) |
|
probably null |
Het |
| Myo1e |
T |
A |
9: 70,246,066 (GRCm39) |
L419Q |
probably damaging |
Het |
| Myo6 |
C |
A |
9: 80,207,854 (GRCm39) |
H1115Q |
probably damaging |
Het |
| Myo7a |
A |
G |
7: 97,756,302 (GRCm39) |
V10A |
probably damaging |
Het |
| Myoz2 |
C |
T |
3: 122,819,776 (GRCm39) |
R61H |
probably damaging |
Het |
| Ncdn |
G |
A |
4: 126,645,796 (GRCm39) |
R38C |
probably damaging |
Het |
| Nckap1 |
T |
A |
2: 80,350,900 (GRCm39) |
T736S |
probably benign |
Het |
| Ncor2 |
G |
A |
5: 125,096,954 (GRCm39) |
A2325V |
probably damaging |
Het |
| Nid2 |
T |
A |
14: 19,802,499 (GRCm39) |
V140E |
possibly damaging |
Het |
| Nlrp9c |
C |
A |
7: 26,079,915 (GRCm39) |
D704Y |
probably benign |
Het |
| Notch3 |
T |
A |
17: 32,377,699 (GRCm39) |
S126C |
probably damaging |
Het |
| Or2g7 |
T |
C |
17: 38,378,839 (GRCm39) |
I259T |
probably damaging |
Het |
| Or5p60 |
A |
G |
7: 107,724,122 (GRCm39) |
F116S |
probably benign |
Het |
| Or5w10 |
A |
T |
2: 87,375,327 (GRCm39) |
L187H |
probably damaging |
Het |
| Or6c219 |
A |
T |
10: 129,781,451 (GRCm39) |
L160* |
probably null |
Het |
| Or6c6c |
T |
C |
10: 129,541,476 (GRCm39) |
M243T |
possibly damaging |
Het |
| Or6d15 |
A |
C |
6: 116,559,658 (GRCm39) |
F83C |
probably damaging |
Het |
| Pdzd7 |
A |
G |
19: 45,027,667 (GRCm39) |
I269T |
probably damaging |
Het |
| Phf3 |
A |
T |
1: 30,845,287 (GRCm39) |
D1299E |
probably damaging |
Het |
| Pitx2 |
T |
A |
3: 129,012,403 (GRCm39) |
Y271N |
probably damaging |
Het |
| Polk |
T |
C |
13: 96,633,140 (GRCm39) |
E301G |
probably damaging |
Het |
| Prkdc |
C |
A |
16: 15,557,388 (GRCm39) |
N2230K |
probably damaging |
Het |
| Prlr |
A |
G |
15: 10,322,622 (GRCm39) |
E170G |
probably benign |
Het |
| Prss55 |
A |
G |
14: 64,313,179 (GRCm39) |
I235T |
probably damaging |
Het |
| Psd3 |
T |
C |
8: 68,413,217 (GRCm39) |
I724V |
probably benign |
Het |
| Rabep2 |
A |
G |
7: 126,037,971 (GRCm39) |
T248A |
possibly damaging |
Het |
| Rbm26 |
T |
A |
14: 105,354,509 (GRCm39) |
K949N |
probably benign |
Het |
| Rnf213 |
T |
A |
11: 119,331,047 (GRCm39) |
D2085E |
probably damaging |
Het |
| Serpinb7 |
A |
T |
1: 107,378,003 (GRCm39) |
H232L |
possibly damaging |
Het |
| Slu7 |
A |
G |
11: 43,336,069 (GRCm39) |
Q484R |
probably benign |
Het |
| Smg1 |
A |
G |
7: 117,745,021 (GRCm39) |
S3044P |
possibly damaging |
Het |
| Snrnp48 |
A |
G |
13: 38,405,336 (GRCm39) |
D248G |
possibly damaging |
Het |
| Snrpc |
C |
A |
17: 28,064,193 (GRCm39) |
P66Q |
unknown |
Het |
| Snrpn |
T |
A |
7: 59,633,207 (GRCm39) |
|
probably benign |
Het |
| Spag17 |
T |
A |
3: 99,846,672 (GRCm39) |
S65R |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,776,408 (GRCm39) |
|
probably benign |
Het |
| Stil |
T |
A |
4: 114,898,979 (GRCm39) |
M1203K |
probably benign |
Het |
| Syt17 |
T |
C |
7: 118,036,061 (GRCm39) |
T106A |
probably benign |
Het |
| Tbx15 |
C |
T |
3: 99,259,562 (GRCm39) |
Q478* |
probably null |
Het |
| Tg |
A |
T |
15: 66,609,397 (GRCm39) |
Q319L |
probably benign |
Het |
| Thada |
A |
G |
17: 84,755,461 (GRCm39) |
L243P |
probably damaging |
Het |
| Thada |
G |
T |
17: 84,755,462 (GRCm39) |
L243I |
probably damaging |
Het |
| Tnnt3 |
A |
G |
7: 142,066,101 (GRCm39) |
R211G |
probably damaging |
Het |
| Togaram1 |
A |
T |
12: 65,049,409 (GRCm39) |
Q1282L |
possibly damaging |
Het |
| Tpm3-rs7 |
T |
G |
14: 113,552,379 (GRCm39) |
M91R |
probably damaging |
Het |
| Trappc9 |
G |
A |
15: 72,897,816 (GRCm39) |
R377W |
probably damaging |
Het |
| Ttll7 |
T |
G |
3: 146,621,535 (GRCm39) |
L378R |
probably damaging |
Het |
| Tyw1 |
T |
G |
5: 130,287,834 (GRCm39) |
I22R |
probably damaging |
Het |
| Ubr3 |
T |
C |
2: 69,846,711 (GRCm39) |
S1645P |
possibly damaging |
Het |
| Ubr4 |
T |
C |
4: 139,120,364 (GRCm39) |
L263P |
probably damaging |
Het |
| Unc13c |
T |
C |
9: 73,663,621 (GRCm39) |
E1071G |
possibly damaging |
Het |
| Vmn2r44 |
G |
T |
7: 8,383,122 (GRCm39) |
D157E |
possibly damaging |
Het |
| Vps16 |
C |
T |
2: 130,285,520 (GRCm39) |
T821I |
probably benign |
Het |
| Washc4 |
T |
C |
10: 83,415,389 (GRCm39) |
V793A |
possibly damaging |
Het |
| Wdr35 |
G |
T |
12: 9,027,435 (GRCm39) |
|
probably null |
Het |
| Zfp277 |
A |
G |
12: 40,414,084 (GRCm39) |
F254L |
probably benign |
Het |
|
| Other mutations in Myo10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00557:Myo10
|
APN |
15 |
25,776,466 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01068:Myo10
|
APN |
15 |
25,739,395 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01352:Myo10
|
APN |
15 |
25,701,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01388:Myo10
|
APN |
15 |
25,736,703 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL01460:Myo10
|
APN |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01553:Myo10
|
APN |
15 |
25,776,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01732:Myo10
|
APN |
15 |
25,732,149 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01992:Myo10
|
APN |
15 |
25,799,634 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Myo10
|
APN |
15 |
25,808,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02045:Myo10
|
APN |
15 |
25,726,574 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02307:Myo10
|
APN |
15 |
25,776,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL02511:Myo10
|
APN |
15 |
25,723,975 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03240:Myo10
|
APN |
15 |
25,701,688 (GRCm39) |
missense |
probably damaging |
1.00 |
|
least
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R0037:Myo10
|
UTSW |
15 |
25,666,618 (GRCm39) |
intron |
probably benign |
|
|
R0153:Myo10
|
UTSW |
15 |
25,781,324 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0282:Myo10
|
UTSW |
15 |
25,793,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Myo10
|
UTSW |
15 |
25,804,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0585:Myo10
|
UTSW |
15 |
25,736,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0617:Myo10
|
UTSW |
15 |
25,738,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Myo10
|
UTSW |
15 |
25,722,243 (GRCm39) |
splice site |
probably benign |
|
|
R0771:Myo10
|
UTSW |
15 |
25,778,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0960:Myo10
|
UTSW |
15 |
25,801,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1562:Myo10
|
UTSW |
15 |
25,780,497 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1651:Myo10
|
UTSW |
15 |
25,742,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1816:Myo10
|
UTSW |
15 |
25,800,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1835:Myo10
|
UTSW |
15 |
25,805,673 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1908:Myo10
|
UTSW |
15 |
25,801,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:Myo10
|
UTSW |
15 |
25,786,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:Myo10
|
UTSW |
15 |
25,722,345 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2129:Myo10
|
UTSW |
15 |
25,781,885 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2141:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2142:Myo10
|
UTSW |
15 |
25,714,194 (GRCm39) |
missense |
probably benign |
|
|
R2920:Myo10
|
UTSW |
15 |
25,801,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2938:Myo10
|
UTSW |
15 |
25,795,803 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3723:Myo10
|
UTSW |
15 |
25,803,374 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3852:Myo10
|
UTSW |
15 |
25,779,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4162:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4163:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4164:Myo10
|
UTSW |
15 |
25,726,501 (GRCm39) |
splice site |
probably null |
|
|
R4177:Myo10
|
UTSW |
15 |
25,734,137 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4409:Myo10
|
UTSW |
15 |
25,807,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4667:Myo10
|
UTSW |
15 |
25,793,239 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4905:Myo10
|
UTSW |
15 |
25,800,298 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4933:Myo10
|
UTSW |
15 |
25,781,204 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4968:Myo10
|
UTSW |
15 |
25,808,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5081:Myo10
|
UTSW |
15 |
25,786,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5123:Myo10
|
UTSW |
15 |
25,726,569 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5310:Myo10
|
UTSW |
15 |
25,778,164 (GRCm39) |
splice site |
probably null |
|
|
R6073:Myo10
|
UTSW |
15 |
25,736,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6117:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6185:Myo10
|
UTSW |
15 |
25,726,596 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6749:Myo10
|
UTSW |
15 |
25,714,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6819:Myo10
|
UTSW |
15 |
25,781,496 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R6875:Myo10
|
UTSW |
15 |
25,805,745 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6908:Myo10
|
UTSW |
15 |
25,804,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo10
|
UTSW |
15 |
25,734,149 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7144:Myo10
|
UTSW |
15 |
25,724,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7266:Myo10
|
UTSW |
15 |
25,783,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7380:Myo10
|
UTSW |
15 |
25,779,706 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7460:Myo10
|
UTSW |
15 |
25,807,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7614:Myo10
|
UTSW |
15 |
25,701,709 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7618:Myo10
|
UTSW |
15 |
25,726,561 (GRCm39) |
nonsense |
probably null |
|
|
R7717:Myo10
|
UTSW |
15 |
25,732,056 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7811:Myo10
|
UTSW |
15 |
25,804,610 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7830:Myo10
|
UTSW |
15 |
25,738,057 (GRCm39) |
nonsense |
probably null |
|
|
R7862:Myo10
|
UTSW |
15 |
25,666,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Myo10
|
UTSW |
15 |
25,804,400 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8264:Myo10
|
UTSW |
15 |
25,800,195 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8377:Myo10
|
UTSW |
15 |
25,804,481 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8385:Myo10
|
UTSW |
15 |
25,804,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8426:Myo10
|
UTSW |
15 |
25,799,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8439:Myo10
|
UTSW |
15 |
25,725,158 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Myo10
|
UTSW |
15 |
25,799,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8775-TAIL:Myo10
|
UTSW |
15 |
25,800,145 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8970:Myo10
|
UTSW |
15 |
25,803,467 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9024:Myo10
|
UTSW |
15 |
25,793,295 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9196:Myo10
|
UTSW |
15 |
25,805,716 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9224:Myo10
|
UTSW |
15 |
25,808,081 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9308:Myo10
|
UTSW |
15 |
25,781,862 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9358:Myo10
|
UTSW |
15 |
25,781,520 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9606:Myo10
|
UTSW |
15 |
25,776,401 (GRCm39) |
frame shift |
probably null |
|
|
R9722:Myo10
|
UTSW |
15 |
25,801,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF013:Myo10
|
UTSW |
15 |
25,799,565 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Myo10
|
UTSW |
15 |
25,799,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Myo10
|
UTSW |
15 |
25,781,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGAATAGAGTCTTCAGTGTACTC -3'
(R):5'- CAGGCTTCCCTCTGACTTACAG -3'
Sequencing Primer
(F):5'- CAGTGTACTCAGGTAAATTACAGTG -3'
(R):5'- GCTTCCCTCTGACTTACAGGAAAAG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation