Incidental Mutation 'R1789:Thada'
| ID |
201681 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
039820-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1789 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84190056-84466196 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 84448034 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Isoleucine
at position 243
(L243I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047524
AA Change: L243I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: L243I
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
G |
A |
16: 20,365,951 (GRCm38) |
P986L |
probably damaging |
Het |
| Acad10 |
A |
T |
5: 121,631,393 (GRCm38) |
Y667N |
possibly damaging |
Het |
| Ahi1 |
G |
A |
10: 20,963,115 (GRCm38) |
G121D |
probably benign |
Het |
| Ampd1 |
T |
A |
3: 103,099,126 (GRCm38) |
I690N |
possibly damaging |
Het |
| Amy1 |
C |
A |
3: 113,558,165 (GRCm38) |
W425L |
possibly damaging |
Het |
| Arhgap27 |
A |
T |
11: 103,333,005 (GRCm38) |
V823E |
probably damaging |
Het |
| Arhgef17 |
A |
G |
7: 100,929,870 (GRCm38) |
S624P |
probably damaging |
Het |
| Arid5b |
T |
C |
10: 68,186,067 (GRCm38) |
H231R |
probably damaging |
Het |
| Aspscr1 |
C |
A |
11: 120,688,560 (GRCm38) |
T78N |
probably damaging |
Het |
| Auts2 |
T |
A |
5: 131,472,450 (GRCm38) |
T42S |
probably damaging |
Het |
| Ccdc171 |
A |
G |
4: 83,554,808 (GRCm38) |
D158G |
probably damaging |
Het |
| Ces4a |
G |
A |
8: 105,138,097 (GRCm38) |
G69S |
probably damaging |
Het |
| Cfap61 |
T |
C |
2: 145,939,993 (GRCm38) |
|
probably null |
Het |
| Chrna5 |
T |
C |
9: 55,004,651 (GRCm38) |
V245A |
possibly damaging |
Het |
| Cntnap5c |
G |
A |
17: 58,013,921 (GRCm38) |
G163R |
probably damaging |
Het |
| Col5a2 |
A |
G |
1: 45,378,305 (GRCm38) |
|
probably null |
Het |
| Col5a2 |
T |
C |
1: 45,394,776 (GRCm38) |
Q759R |
probably damaging |
Het |
| Comp |
A |
G |
8: 70,377,146 (GRCm38) |
D340G |
probably benign |
Het |
| Cyfip1 |
T |
A |
7: 55,926,395 (GRCm38) |
D1104E |
probably damaging |
Het |
| Dnah11 |
A |
T |
12: 118,038,780 (GRCm38) |
S308T |
probably damaging |
Het |
| Dnah5 |
A |
G |
15: 28,270,426 (GRCm38) |
H958R |
probably benign |
Het |
| Elp3 |
A |
G |
14: 65,547,919 (GRCm38) |
Y478H |
probably damaging |
Het |
| Fat3 |
T |
C |
9: 16,376,985 (GRCm38) |
Y414C |
probably benign |
Het |
| Fbxo10 |
C |
A |
4: 45,046,389 (GRCm38) |
A574S |
probably damaging |
Het |
| Fsip2 |
G |
T |
2: 82,977,562 (GRCm38) |
L1408F |
probably benign |
Het |
| Fubp3 |
T |
C |
2: 31,611,735 (GRCm38) |
V425A |
possibly damaging |
Het |
| Gm7168 |
A |
T |
17: 13,949,584 (GRCm38) |
R404S |
probably benign |
Het |
| Gm8773 |
A |
T |
5: 5,575,652 (GRCm38) |
Q116L |
possibly damaging |
Het |
| Gpd1 |
T |
G |
15: 99,723,202 (GRCm38) |
F299C |
probably damaging |
Het |
| Gpr137 |
C |
T |
19: 6,942,057 (GRCm38) |
|
probably benign |
Het |
| Grin3b |
T |
C |
10: 79,973,408 (GRCm38) |
S331P |
probably benign |
Het |
| Grk3 |
T |
A |
5: 112,941,718 (GRCm38) |
I281F |
probably damaging |
Het |
| Hoxb7 |
T |
A |
11: 96,286,781 (GRCm38) |
S18R |
probably damaging |
Het |
| Igf1r |
C |
T |
7: 68,214,933 (GRCm38) |
R1160* |
probably null |
Het |
| Itfg1 |
A |
G |
8: 85,725,512 (GRCm38) |
|
probably null |
Het |
| Itgb8 |
T |
C |
12: 119,202,455 (GRCm38) |
I114V |
probably benign |
Het |
| Kcnk1 |
A |
G |
8: 126,025,384 (GRCm38) |
E243G |
possibly damaging |
Het |
| Kif27 |
A |
G |
13: 58,344,008 (GRCm38) |
L439P |
probably damaging |
Het |
| Kif2c |
T |
A |
4: 117,167,361 (GRCm38) |
Q279L |
probably benign |
Het |
| Kmt2d |
A |
T |
15: 98,852,074 (GRCm38) |
|
probably benign |
Het |
| L3mbtl1 |
A |
G |
2: 162,974,502 (GRCm38) |
T821A |
probably benign |
Het |
| Lrrc24 |
A |
T |
15: 76,722,578 (GRCm38) |
M206K |
probably benign |
Het |
| Mamdc4 |
T |
G |
2: 25,567,622 (GRCm38) |
K460Q |
possibly damaging |
Het |
| Maml2 |
C |
G |
9: 13,697,345 (GRCm38) |
L30V |
probably damaging |
Het |
| Mc5r |
C |
G |
18: 68,338,670 (GRCm38) |
|
probably null |
Het |
| Myo10 |
T |
G |
15: 25,726,525 (GRCm38) |
|
probably null |
Het |
| Myo1e |
T |
A |
9: 70,338,784 (GRCm38) |
L419Q |
probably damaging |
Het |
| Myo6 |
C |
A |
9: 80,300,572 (GRCm38) |
H1115Q |
probably damaging |
Het |
| Myo7a |
A |
G |
7: 98,107,095 (GRCm38) |
V10A |
probably damaging |
Het |
| Myoz2 |
C |
T |
3: 123,026,127 (GRCm38) |
R61H |
probably damaging |
Het |
| Ncdn |
G |
A |
4: 126,752,003 (GRCm38) |
R38C |
probably damaging |
Het |
| Nckap1 |
T |
A |
2: 80,520,556 (GRCm38) |
T736S |
probably benign |
Het |
| Ncor2 |
G |
A |
5: 125,019,890 (GRCm38) |
A2325V |
probably damaging |
Het |
| Nid2 |
T |
A |
14: 19,752,431 (GRCm38) |
V140E |
possibly damaging |
Het |
| Nlrp9c |
C |
A |
7: 26,380,490 (GRCm38) |
D704Y |
probably benign |
Het |
| Notch3 |
T |
A |
17: 32,158,725 (GRCm38) |
S126C |
probably damaging |
Het |
| Olfr1128 |
A |
T |
2: 87,544,983 (GRCm38) |
L187H |
probably damaging |
Het |
| Olfr130 |
T |
C |
17: 38,067,948 (GRCm38) |
I259T |
probably damaging |
Het |
| Olfr215 |
A |
C |
6: 116,582,697 (GRCm38) |
F83C |
probably damaging |
Het |
| Olfr484 |
A |
G |
7: 108,124,915 (GRCm38) |
F116S |
probably benign |
Het |
| Olfr804 |
T |
C |
10: 129,705,607 (GRCm38) |
M243T |
possibly damaging |
Het |
| Olfr818 |
A |
T |
10: 129,945,582 (GRCm38) |
L160* |
probably null |
Het |
| Pdzd7 |
A |
G |
19: 45,039,228 (GRCm38) |
I269T |
probably damaging |
Het |
| Phf3 |
A |
T |
1: 30,806,206 (GRCm38) |
D1299E |
probably damaging |
Het |
| Pitx2 |
T |
A |
3: 129,218,754 (GRCm38) |
Y271N |
probably damaging |
Het |
| Polk |
T |
C |
13: 96,496,632 (GRCm38) |
E301G |
probably damaging |
Het |
| Prkdc |
C |
A |
16: 15,739,524 (GRCm38) |
N2230K |
probably damaging |
Het |
| Prlr |
A |
G |
15: 10,322,536 (GRCm38) |
E170G |
probably benign |
Het |
| Prss55 |
A |
G |
14: 64,075,730 (GRCm38) |
I235T |
probably damaging |
Het |
| Psd3 |
T |
C |
8: 67,960,565 (GRCm38) |
I724V |
probably benign |
Het |
| Rabep2 |
A |
G |
7: 126,438,799 (GRCm38) |
T248A |
possibly damaging |
Het |
| Rbm26 |
T |
A |
14: 105,117,073 (GRCm38) |
K949N |
probably benign |
Het |
| Rnf213 |
T |
A |
11: 119,440,221 (GRCm38) |
D2085E |
probably damaging |
Het |
| Serpinb7 |
A |
T |
1: 107,450,273 (GRCm38) |
H232L |
possibly damaging |
Het |
| Slu7 |
A |
G |
11: 43,445,242 (GRCm38) |
Q484R |
probably benign |
Het |
| Smg1 |
A |
G |
7: 118,145,798 (GRCm38) |
S3044P |
possibly damaging |
Het |
| Snrnp48 |
A |
G |
13: 38,221,360 (GRCm38) |
D248G |
possibly damaging |
Het |
| Snrpc |
C |
A |
17: 27,845,219 (GRCm38) |
P66Q |
unknown |
Het |
| Snrpn |
T |
A |
7: 59,983,459 (GRCm38) |
|
probably benign |
Het |
| Spag17 |
T |
A |
3: 99,939,356 (GRCm38) |
S65R |
possibly damaging |
Het |
| Srsf6 |
C |
A |
2: 162,934,488 (GRCm38) |
|
probably benign |
Het |
| Stil |
T |
A |
4: 115,041,782 (GRCm38) |
M1203K |
probably benign |
Het |
| Syt17 |
T |
C |
7: 118,436,838 (GRCm38) |
T106A |
probably benign |
Het |
| Tbx15 |
C |
T |
3: 99,352,246 (GRCm38) |
Q478* |
probably null |
Het |
| Tg |
A |
T |
15: 66,737,548 (GRCm38) |
Q319L |
probably benign |
Het |
| Tnnt3 |
A |
G |
7: 142,512,364 (GRCm38) |
R211G |
probably damaging |
Het |
| Togaram1 |
A |
T |
12: 65,002,635 (GRCm38) |
Q1282L |
possibly damaging |
Het |
| Tpm3-rs7 |
T |
G |
14: 113,314,947 (GRCm38) |
M91R |
probably damaging |
Het |
| Trappc9 |
G |
A |
15: 73,025,967 (GRCm38) |
R377W |
probably damaging |
Het |
| Ttll7 |
T |
G |
3: 146,915,780 (GRCm38) |
L378R |
probably damaging |
Het |
| Tyw1 |
T |
G |
5: 130,258,993 (GRCm38) |
I22R |
probably damaging |
Het |
| Ubr3 |
T |
C |
2: 70,016,367 (GRCm38) |
S1645P |
possibly damaging |
Het |
| Ubr4 |
T |
C |
4: 139,393,053 (GRCm38) |
L263P |
probably damaging |
Het |
| Unc13c |
T |
C |
9: 73,756,339 (GRCm38) |
E1071G |
possibly damaging |
Het |
| Vmn2r44 |
G |
T |
7: 8,380,123 (GRCm38) |
D157E |
possibly damaging |
Het |
| Vps16 |
C |
T |
2: 130,443,600 (GRCm38) |
T821I |
probably benign |
Het |
| Washc4 |
T |
C |
10: 83,579,525 (GRCm38) |
V793A |
possibly damaging |
Het |
| Wdr35 |
G |
T |
12: 8,977,435 (GRCm38) |
|
probably null |
Het |
| Zfp277 |
A |
G |
12: 40,364,085 (GRCm38) |
F254L |
probably benign |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,444,218 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,447,976 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,393,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,446,688 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,446,644 (GRCm38) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,222,766 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,222,766 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,428,697 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,444,028 (GRCm38) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,458,849 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,435,560 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,398,205 (GRCm38) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,446,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,334,141 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,226,040 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,455,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,455,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,230,936 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,231,096 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,423,163 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,416,303 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,229,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,336,829 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,436,655 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,429,062 (GRCm38) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,252,435 (GRCm38) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,436,676 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,436,676 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,446,601 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,448,033 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,464,407 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,231,114 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,226,004 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,436,702 (GRCm38) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,444,499 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,310,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,310,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,310,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,441,764 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,446,521 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,454,640 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,230,785 (GRCm38) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,230,785 (GRCm38) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,441,782 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,441,707 (GRCm38) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,426,237 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,435,650 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,426,186 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,458,855 (GRCm38) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,272,817 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,441,104 (GRCm38) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,446,599 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,448,042 (GRCm38) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,252,400 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,444,226 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,444,183 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,386,532 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,444,468 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,426,186 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,432,254 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,429,130 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,416,399 (GRCm38) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,191,983 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,451,727 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,230,901 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,436,634 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,272,800 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,192,006 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,393,367 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,436,602 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,429,173 (GRCm38) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,416,323 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,443,911 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,454,414 (GRCm38) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,393,469 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,230,786 (GRCm38) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,230,963 (GRCm38) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,464,366 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,226,041 (GRCm38) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,252,390 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,451,837 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,429,196 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,272,769 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,192,205 (GRCm38) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,393,427 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,226,040 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,222,703 (GRCm38) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,435,629 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,432,346 (GRCm38) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,229,209 (GRCm38) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,429,096 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,231,087 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,451,775 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,429,201 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,231,161 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,441,744 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,231,136 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,231,161 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,441,777 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,441,777 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,191,982 (GRCm38) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,458,864 (GRCm38) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,429,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,426,177 (GRCm38) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,231,156 (GRCm38) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,444,430 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTGCCCATACACACGCC -3'
(R):5'- GTGCCAGAGATGTAGATAGTAAGGT -3'
Sequencing Primer
(F):5'- CATACACACGCCACAAATAAATAAC -3'
(R):5'- TCAGGTATGAGTTATTAACCCCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation