Incidental Mutation 'R1792:Adgrb3'
| ID |
201796 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgrb3
|
| Ensembl Gene |
ENSMUSG00000033569 |
| Gene Name |
adhesion G protein-coupled receptor B3 |
| Synonyms |
Bai3, A830096D10Rik |
| MMRRC Submission |
039822-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.350)
|
| Stock # |
R1792 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
25106557-25868788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 25267552 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 853
(C853S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116231
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041838]
[ENSMUST00000126626]
[ENSMUST00000135518]
[ENSMUST00000146592]
[ENSMUST00000151309]
|
| AlphaFold |
Q80ZF8 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041838
AA Change: C853S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000035612
Gene: ENSMUSG00000033569
AA Change: C853S
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000119680
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000126096
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000126626
|
| SMART Domains |
Protein: ENSMUSP00000115442
Gene: ENSMUSG00000033569
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:7tm_2
|
4 |
273 |
7.3e-65 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134022
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000135518
AA Change: C853S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000119804
Gene: ENSMUSG00000033569
AA Change: C853S
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
586 |
810 |
1.7e-52 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
874 |
1143 |
2.1e-64 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000146592
AA Change: C646S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000116759
Gene: ENSMUSG00000033569
AA Change: C646S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
16 |
N/A |
INTRINSIC |
|
TSP1
|
87 |
136 |
2.1e-12 |
SMART |
|
TSP1
|
141 |
191 |
7.97e-13 |
SMART |
|
TSP1
|
196 |
246 |
6.28e-11 |
SMART |
|
TSP1
|
251 |
301 |
1.48e-7 |
SMART |
|
HormR
|
303 |
369 |
4.15e-20 |
SMART |
|
Pfam:DUF3497
|
379 |
603 |
2.5e-52 |
PFAM |
|
GPS
|
608 |
661 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
667 |
903 |
5.4e-66 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000151309
AA Change: C853S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000116231
Gene: ENSMUSG00000033569
AA Change: C853S
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
7 |
29 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
TSP1
|
294 |
343 |
2.1e-12 |
SMART |
|
TSP1
|
348 |
398 |
7.97e-13 |
SMART |
|
TSP1
|
403 |
453 |
6.28e-11 |
SMART |
|
TSP1
|
458 |
508 |
1.48e-7 |
SMART |
|
HormR
|
510 |
576 |
4.15e-20 |
SMART |
|
Pfam:GAIN
|
589 |
794 |
1.1e-44 |
PFAM |
|
GPS
|
815 |
868 |
1.24e-21 |
SMART |
|
Pfam:7tm_2
|
875 |
1143 |
2.7e-63 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153568
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a conditional allele activated in Purkinje cells exhibit impaired motor learning with alterned climbing fiber electrophysiology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
C |
T |
11: 110,074,870 (GRCm39) |
V1398I |
probably benign |
Het |
| Ackr3 |
A |
T |
1: 90,142,620 (GRCm39) |
N360Y |
probably benign |
Het |
| Acr |
T |
G |
15: 89,457,346 (GRCm39) |
M198R |
probably benign |
Het |
| Adamts14 |
A |
T |
10: 61,054,277 (GRCm39) |
M585K |
probably benign |
Het |
| Arhgef28 |
G |
T |
13: 98,067,694 (GRCm39) |
S1410R |
probably benign |
Het |
| Asprv1 |
T |
A |
6: 86,605,354 (GRCm39) |
F67I |
possibly damaging |
Het |
| Atp8b4 |
T |
A |
2: 126,167,214 (GRCm39) |
Y1095F |
probably benign |
Het |
| Cadps |
A |
G |
14: 12,449,802 (GRCm38) |
S1136P |
possibly damaging |
Het |
| Ccdc57 |
T |
C |
11: 120,788,707 (GRCm39) |
Q380R |
possibly damaging |
Het |
| Cdc45 |
A |
T |
16: 18,626,090 (GRCm39) |
D142E |
probably benign |
Het |
| Cs |
A |
T |
10: 128,195,948 (GRCm39) |
N386Y |
possibly damaging |
Het |
| Dsc3 |
A |
T |
18: 20,120,055 (GRCm39) |
V201E |
probably damaging |
Het |
| Dusp26 |
G |
T |
8: 31,581,963 (GRCm39) |
R19L |
probably benign |
Het |
| Esyt3 |
C |
A |
9: 99,240,169 (GRCm39) |
E92* |
probably null |
Het |
| Ext2 |
T |
C |
2: 93,534,890 (GRCm39) |
N625D |
probably damaging |
Het |
| Flvcr2 |
A |
T |
12: 85,793,929 (GRCm39) |
K102* |
probably null |
Het |
| Fmnl2 |
T |
A |
2: 52,932,329 (GRCm39) |
S103T |
possibly damaging |
Het |
| Fmo4 |
T |
A |
1: 162,621,859 (GRCm39) |
I451F |
probably benign |
Het |
| Gak |
A |
T |
5: 108,733,397 (GRCm39) |
Y47* |
probably null |
Het |
| Gbp10 |
A |
T |
5: 105,372,166 (GRCm39) |
L198Q |
probably damaging |
Het |
| Gm11559 |
T |
A |
11: 99,755,755 (GRCm39) |
S135T |
unknown |
Het |
| Gm14496 |
A |
T |
2: 181,637,946 (GRCm39) |
D340V |
probably benign |
Het |
| Grin2a |
T |
C |
16: 9,810,259 (GRCm39) |
T47A |
possibly damaging |
Het |
| Gtf2ird1 |
A |
T |
5: 134,395,790 (GRCm39) |
|
probably null |
Het |
| Herc4 |
T |
A |
10: 63,081,680 (GRCm39) |
M1K |
probably null |
Het |
| Hirip3 |
T |
A |
7: 126,461,792 (GRCm39) |
V29E |
probably damaging |
Het |
| Hs3st5 |
A |
G |
10: 36,708,720 (GRCm39) |
D85G |
probably benign |
Het |
| Htt |
T |
A |
5: 35,064,543 (GRCm39) |
S2981T |
probably damaging |
Het |
| Iho1 |
A |
C |
9: 108,282,111 (GRCm39) |
S526A |
possibly damaging |
Het |
| Il20ra |
G |
A |
10: 19,635,384 (GRCm39) |
V542I |
probably damaging |
Het |
| Itgb2l |
C |
A |
16: 96,226,282 (GRCm39) |
C603F |
probably damaging |
Het |
| Klhl41 |
A |
C |
2: 69,501,146 (GRCm39) |
K202N |
probably benign |
Het |
| Lct |
G |
A |
1: 128,255,679 (GRCm39) |
S121F |
possibly damaging |
Het |
| Lhx6 |
C |
T |
2: 35,977,387 (GRCm39) |
G355D |
probably damaging |
Het |
| Limk2 |
A |
G |
11: 3,308,236 (GRCm39) |
V121A |
probably benign |
Het |
| Med1 |
T |
G |
11: 98,048,109 (GRCm39) |
K896Q |
probably damaging |
Het |
| Muc6 |
A |
G |
7: 141,214,371 (GRCm39) |
F2789S |
probably benign |
Het |
| Nemf |
T |
A |
12: 69,359,343 (GRCm39) |
Y997F |
probably damaging |
Het |
| Nrap |
A |
G |
19: 56,367,590 (GRCm39) |
S296P |
probably benign |
Het |
| Nrxn1 |
T |
C |
17: 90,896,252 (GRCm39) |
N961D |
probably damaging |
Het |
| Odad2 |
T |
C |
18: 7,286,743 (GRCm39) |
T163A |
probably benign |
Het |
| Or1r1 |
A |
C |
11: 73,874,673 (GRCm39) |
S254A |
probably benign |
Het |
| Or6c207 |
A |
T |
10: 129,105,112 (GRCm39) |
F27I |
probably benign |
Het |
| Or6y1 |
T |
C |
1: 174,276,303 (GRCm39) |
V38A |
probably benign |
Het |
| Parp14 |
G |
A |
16: 35,677,130 (GRCm39) |
A946V |
probably benign |
Het |
| Pdk4 |
T |
A |
6: 5,489,166 (GRCm39) |
H247L |
probably damaging |
Het |
| Pkd1l3 |
T |
A |
8: 110,359,237 (GRCm39) |
V866E |
probably damaging |
Het |
| Pla2g4e |
G |
A |
2: 119,998,955 (GRCm39) |
P803L |
probably damaging |
Het |
| Pnisr |
T |
C |
4: 21,860,968 (GRCm39) |
V217A |
possibly damaging |
Het |
| Pole4 |
G |
A |
6: 82,629,720 (GRCm39) |
P34L |
unknown |
Het |
| Pole4 |
G |
T |
6: 82,629,721 (GRCm39) |
P34T |
unknown |
Het |
| Ptchd3 |
G |
A |
11: 121,732,377 (GRCm39) |
W422* |
probably null |
Het |
| Rab1b |
C |
T |
19: 5,150,513 (GRCm39) |
A167T |
probably benign |
Het |
| Rasal1 |
T |
C |
5: 120,802,821 (GRCm39) |
M359T |
probably benign |
Het |
| Rexo4 |
T |
C |
2: 26,850,248 (GRCm39) |
N310D |
probably benign |
Het |
| Rgma |
C |
T |
7: 73,067,585 (GRCm39) |
T280M |
probably damaging |
Het |
| Rnaset2a |
A |
T |
17: 8,364,408 (GRCm39) |
I43N |
probably damaging |
Het |
| Rtcb |
A |
T |
10: 85,778,446 (GRCm39) |
V399E |
probably damaging |
Het |
| Scd4 |
T |
G |
19: 44,326,013 (GRCm39) |
Y122* |
probably null |
Het |
| Sirt6 |
T |
C |
10: 81,462,355 (GRCm39) |
I15V |
possibly damaging |
Het |
| Slamf8 |
A |
T |
1: 172,415,526 (GRCm39) |
V104E |
possibly damaging |
Het |
| Slc12a4 |
A |
G |
8: 106,678,475 (GRCm39) |
I285T |
possibly damaging |
Het |
| Slc25a13 |
G |
A |
6: 6,115,104 (GRCm39) |
A207V |
possibly damaging |
Het |
| Slc6a21 |
T |
C |
7: 44,930,155 (GRCm39) |
S185P |
probably benign |
Het |
| Smarcc2 |
A |
C |
10: 128,299,740 (GRCm39) |
N135T |
probably damaging |
Het |
| Susd6 |
T |
C |
12: 80,921,065 (GRCm39) |
S221P |
probably damaging |
Het |
| Syne1 |
C |
T |
10: 4,990,975 (GRCm39) |
G8418D |
probably damaging |
Het |
| Tasor2 |
T |
C |
13: 3,640,559 (GRCm39) |
K193E |
possibly damaging |
Het |
| Tbc1d7 |
C |
T |
13: 43,318,853 (GRCm39) |
V95I |
probably benign |
Het |
| Tcerg1l |
T |
C |
7: 137,963,595 (GRCm39) |
D225G |
probably benign |
Het |
| Tfip11 |
A |
T |
5: 112,477,263 (GRCm39) |
I82F |
possibly damaging |
Het |
| Tmem41a |
C |
T |
16: 21,755,731 (GRCm39) |
G192S |
probably null |
Het |
| Trrap |
G |
A |
5: 144,790,396 (GRCm39) |
A3619T |
possibly damaging |
Het |
| Tspoap1 |
G |
A |
11: 87,656,707 (GRCm39) |
|
probably null |
Het |
| Wfdc21 |
T |
C |
11: 83,637,883 (GRCm39) |
S11P |
probably benign |
Het |
| Zc2hc1b |
A |
T |
10: 13,044,474 (GRCm39) |
V63E |
probably damaging |
Het |
|
| Other mutations in Adgrb3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00164:Adgrb3
|
APN |
1 |
25,267,581 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL00507:Adgrb3
|
APN |
1 |
25,113,796 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00828:Adgrb3
|
APN |
1 |
25,527,200 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL01285:Adgrb3
|
APN |
1 |
25,132,868 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01309:Adgrb3
|
APN |
1 |
25,151,352 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01540:Adgrb3
|
APN |
1 |
25,151,252 (GRCm39) |
splice site |
probably null |
|
|
IGL01608:Adgrb3
|
APN |
1 |
25,592,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01638:Adgrb3
|
APN |
1 |
25,598,832 (GRCm39) |
splice site |
probably benign |
|
|
IGL01657:Adgrb3
|
APN |
1 |
25,865,574 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01666:Adgrb3
|
APN |
1 |
25,499,832 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01712:Adgrb3
|
APN |
1 |
25,865,360 (GRCm39) |
missense |
probably benign |
|
|
IGL01767:Adgrb3
|
APN |
1 |
25,598,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01987:Adgrb3
|
APN |
1 |
25,140,512 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02201:Adgrb3
|
APN |
1 |
25,459,631 (GRCm39) |
splice site |
probably benign |
|
|
IGL02584:Adgrb3
|
APN |
1 |
25,544,065 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02685:Adgrb3
|
APN |
1 |
25,123,323 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02886:Adgrb3
|
APN |
1 |
25,543,991 (GRCm39) |
splice site |
probably null |
|
|
IGL02929:Adgrb3
|
APN |
1 |
25,592,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03153:Adgrb3
|
APN |
1 |
25,570,978 (GRCm39) |
nonsense |
probably null |
|
|
IGL03165:Adgrb3
|
APN |
1 |
25,133,475 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03227:Adgrb3
|
APN |
1 |
25,586,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03392:Adgrb3
|
APN |
1 |
25,543,529 (GRCm39) |
missense |
probably damaging |
0.99 |
|
schwach
|
UTSW |
1 |
25,150,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0007:Adgrb3
|
UTSW |
1 |
25,150,772 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0048:Adgrb3
|
UTSW |
1 |
25,140,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0048:Adgrb3
|
UTSW |
1 |
25,140,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0322:Adgrb3
|
UTSW |
1 |
25,260,829 (GRCm39) |
splice site |
probably benign |
|
|
R0442:Adgrb3
|
UTSW |
1 |
25,435,551 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0563:Adgrb3
|
UTSW |
1 |
25,586,635 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1168:Adgrb3
|
UTSW |
1 |
25,865,280 (GRCm39) |
missense |
probably benign |
|
|
R1252:Adgrb3
|
UTSW |
1 |
25,167,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1264:Adgrb3
|
UTSW |
1 |
25,598,931 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1543:Adgrb3
|
UTSW |
1 |
25,527,169 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1577:Adgrb3
|
UTSW |
1 |
25,133,264 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1581:Adgrb3
|
UTSW |
1 |
25,133,153 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1583:Adgrb3
|
UTSW |
1 |
25,265,912 (GRCm39) |
splice site |
probably null |
|
|
R1653:Adgrb3
|
UTSW |
1 |
25,140,584 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1725:Adgrb3
|
UTSW |
1 |
25,865,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1827:Adgrb3
|
UTSW |
1 |
25,571,658 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1838:Adgrb3
|
UTSW |
1 |
25,123,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1869:Adgrb3
|
UTSW |
1 |
25,865,519 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1971:Adgrb3
|
UTSW |
1 |
25,586,525 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2005:Adgrb3
|
UTSW |
1 |
25,150,799 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2134:Adgrb3
|
UTSW |
1 |
25,133,038 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2142:Adgrb3
|
UTSW |
1 |
25,107,290 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2268:Adgrb3
|
UTSW |
1 |
25,150,898 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3740:Adgrb3
|
UTSW |
1 |
25,865,535 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3877:Adgrb3
|
UTSW |
1 |
25,150,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4120:Adgrb3
|
UTSW |
1 |
25,133,388 (GRCm39) |
nonsense |
probably null |
|
|
R4344:Adgrb3
|
UTSW |
1 |
25,865,829 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4363:Adgrb3
|
UTSW |
1 |
25,151,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4438:Adgrb3
|
UTSW |
1 |
25,870,108 (GRCm39) |
unclassified |
probably benign |
|
|
R4465:Adgrb3
|
UTSW |
1 |
25,133,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4480:Adgrb3
|
UTSW |
1 |
25,150,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4554:Adgrb3
|
UTSW |
1 |
25,123,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4557:Adgrb3
|
UTSW |
1 |
25,123,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4622:Adgrb3
|
UTSW |
1 |
25,865,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4713:Adgrb3
|
UTSW |
1 |
25,586,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4772:Adgrb3
|
UTSW |
1 |
25,570,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4890:Adgrb3
|
UTSW |
1 |
25,260,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5045:Adgrb3
|
UTSW |
1 |
25,113,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5061:Adgrb3
|
UTSW |
1 |
25,107,209 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5097:Adgrb3
|
UTSW |
1 |
25,865,165 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5227:Adgrb3
|
UTSW |
1 |
25,133,033 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5241:Adgrb3
|
UTSW |
1 |
25,150,871 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5328:Adgrb3
|
UTSW |
1 |
25,133,356 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5372:Adgrb3
|
UTSW |
1 |
25,167,940 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5703:Adgrb3
|
UTSW |
1 |
25,459,640 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5747:Adgrb3
|
UTSW |
1 |
25,865,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5998:Adgrb3
|
UTSW |
1 |
25,470,582 (GRCm39) |
splice site |
probably null |
|
|
R6006:Adgrb3
|
UTSW |
1 |
25,865,612 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6077:Adgrb3
|
UTSW |
1 |
25,133,081 (GRCm39) |
nonsense |
probably null |
|
|
R6183:Adgrb3
|
UTSW |
1 |
25,133,451 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6190:Adgrb3
|
UTSW |
1 |
25,459,728 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6249:Adgrb3
|
UTSW |
1 |
25,471,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Adgrb3
|
UTSW |
1 |
25,150,799 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6450:Adgrb3
|
UTSW |
1 |
25,459,683 (GRCm39) |
missense |
probably benign |
|
|
R6678:Adgrb3
|
UTSW |
1 |
25,499,891 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6679:Adgrb3
|
UTSW |
1 |
25,170,377 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6685:Adgrb3
|
UTSW |
1 |
25,150,817 (GRCm39) |
nonsense |
probably null |
|
|
R6730:Adgrb3
|
UTSW |
1 |
25,133,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6805:Adgrb3
|
UTSW |
1 |
25,865,253 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6847:Adgrb3
|
UTSW |
1 |
25,133,003 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6929:Adgrb3
|
UTSW |
1 |
25,150,852 (GRCm39) |
nonsense |
probably null |
|
|
R6953:Adgrb3
|
UTSW |
1 |
25,865,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Adgrb3
|
UTSW |
1 |
25,865,166 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7244:Adgrb3
|
UTSW |
1 |
25,170,350 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7292:Adgrb3
|
UTSW |
1 |
25,570,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7325:Adgrb3
|
UTSW |
1 |
25,571,711 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7378:Adgrb3
|
UTSW |
1 |
25,571,000 (GRCm39) |
nonsense |
probably null |
|
|
R7489:Adgrb3
|
UTSW |
1 |
25,586,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7615:Adgrb3
|
UTSW |
1 |
25,137,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7623:Adgrb3
|
UTSW |
1 |
25,586,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7787:Adgrb3
|
UTSW |
1 |
25,471,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7837:Adgrb3
|
UTSW |
1 |
25,167,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8064:Adgrb3
|
UTSW |
1 |
25,459,637 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8152:Adgrb3
|
UTSW |
1 |
25,260,838 (GRCm39) |
splice site |
probably null |
|
|
R8161:Adgrb3
|
UTSW |
1 |
25,133,003 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8225:Adgrb3
|
UTSW |
1 |
25,865,597 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8417:Adgrb3
|
UTSW |
1 |
25,527,134 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8694:Adgrb3
|
UTSW |
1 |
25,865,472 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8742:Adgrb3
|
UTSW |
1 |
25,265,835 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8886:Adgrb3
|
UTSW |
1 |
25,150,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8941:Adgrb3
|
UTSW |
1 |
25,133,235 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8958:Adgrb3
|
UTSW |
1 |
25,865,190 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8979:Adgrb3
|
UTSW |
1 |
25,527,115 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9064:Adgrb3
|
UTSW |
1 |
25,570,965 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9252:Adgrb3
|
UTSW |
1 |
25,865,496 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9401:Adgrb3
|
UTSW |
1 |
25,592,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9739:Adgrb3
|
UTSW |
1 |
25,592,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Adgrb3
|
UTSW |
1 |
25,170,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgrb3
|
UTSW |
1 |
25,132,995 (GRCm39) |
missense |
probably benign |
0.37 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAACAACCCGATTTTGCCAC -3'
(R):5'- TTACGTCCTGTTCAACAACAAGTAG -3'
Sequencing Primer
(F):5'- CCGATTTTGCCACCCTGC -3'
(R):5'- TACGGGAATTACAGTAGGCGATTCTC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation