Mutagenetix > Incidental Mutation

Incidental Mutation 'R1793:Tenm3'

201943

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Ten-m3, Odz3, 2610100B16Rik

MMRRC Submission

039823-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.598) question?

Stock #

R1793 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

48227682-48843951 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 48674544 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Tyrosine at position 33 (C33Y)

Ref Sequence

ENSEMBL: ENSMUSP00000148666 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840] [ENSMUST00000211812]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000033965
AA Change: C33Y

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: C33Y

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000190840
AA Change: C33Y

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: C33Y

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000211812
AA Change: C33Y

PolyPhen 2 Score 0.979 (Sensitivity: 0.75; Specificity: 0.96)

Meta Mutation Damage Score

0.1190

Coding Region Coverage

1x: 97.5%
3x: 96.9%
10x: 95.4%
20x: 92.9%

Validation Efficiency

100% (122/122)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 118 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930522L14Rik	A	T	5: 109,736,278	H571Q	probably damaging	Het
Abcf2	T	A	5: 24,568,776	M372L	probably benign	Het
Acaca	A	G	11: 84,338,393	D1682G	probably damaging	Het
Acaca	A	C	11: 84,315,969	T1552P	probably damaging	Het
Acvr1b	T	C	15: 101,194,025	V62A	probably benign	Het
Aimp1	C	T	3: 132,674,064	V97M	probably benign	Het
Aldh1l1	C	T	6: 90,577,831	T557I	possibly damaging	Het
Alpk1	T	C	3: 127,677,798	T1012A	probably damaging	Het
Amot	G	A	X: 145,450,589		probably benign	Het
Arap1	T	A	7: 101,388,622	H477Q	probably benign	Het
Arhgap18	T	A	10: 26,860,736		probably benign	Het
Arhgef10l	C	T	4: 140,515,373	V862M	probably damaging	Het
Arl4d	A	G	11: 101,666,728	I27V	probably benign	Het
Asb18	G	A	1: 90,014,555	P8L	probably damaging	Het
Ash1l	A	G	3: 89,070,309	H2682R	probably damaging	Het
Aspm	T	A	1: 139,457,341	V241E	probably benign	Het
Atf7ip	G	T	6: 136,609,219		probably benign	Het
AY358078	T	G	14: 51,804,594	M142R	unknown	Het
C3	T	A	17: 57,219,592	K796N	possibly damaging	Het
Cd3eap	T	C	7: 19,357,979	T68A	possibly damaging	Het
Ceacam16	T	C	7: 19,856,116	T301A	probably damaging	Het
Ceacam5	T	G	7: 17,747,395	Y356D	probably benign	Het
Cep192	C	T	18: 67,851,767	A1616V	possibly damaging	Het
Cherp	A	T	8: 72,463,150	H645Q	probably benign	Het
CK137956	T	C	4: 127,951,449	D167G	probably benign	Het
Clcn1	T	A	6: 42,298,926		probably null	Het
Cntn1	C	T	15: 92,291,671	T625I	possibly damaging	Het
Cpn2	T	A	16: 30,259,324	N520Y	probably damaging	Het
Crocc	G	A	4: 141,019,309	R1762W	probably damaging	Het
Cts3	C	A	13: 61,568,153	V100F	probably benign	Het
Ddx56	A	T	11: 6,266,934	V87D	probably damaging	Het
Dnah9	C	T	11: 66,119,594		probably null	Het
Dock1	T	A	7: 135,098,727		probably null	Het
Dst	T	A	1: 34,152,471	Y291*	probably null	Het
Eif4g3	T	C	4: 138,171,131	I1071T	probably damaging	Het
Fblim1	T	C	4: 141,595,238	Q78R	probably damaging	Het
Fcamr	C	T	1: 130,811,547	P195S	probably benign	Het
Fcho1	G	A	8: 71,709,022	Q835*	probably null	Het
Frem3	A	G	8: 80,613,112	N678S	probably benign	Het
Frk	G	A	10: 34,607,882	R413H	probably benign	Het
Gm10619	C	A	7: 73,810,010		noncoding transcript	Het
Gm12185	G	A	11: 48,915,756	R203*	probably null	Het
Gm12886	A	G	4: 121,422,977	V34A	probably benign	Het
Gna12	A	T	5: 140,760,952	I246N	probably damaging	Het
Gpm6a	T	C	8: 55,054,832	M201T	probably benign	Het
Gpsm2	T	G	3: 108,700,909	D220A	probably benign	Het
Grip2	C	G	6: 91,783,642	V325L	probably benign	Het
Grk5	C	A	19: 61,076,762	A288D	probably damaging	Het
Herpud2	G	A	9: 25,110,657	A231V	possibly damaging	Het
Hmcn1	T	C	1: 150,749,083	S1024G	probably benign	Het
Hp1bp3	A	G	4: 138,230,509	D295G	probably damaging	Het
Igsf21	T	C	4: 140,034,392	H325R	probably damaging	Het
Ing2	T	A	8: 47,669,329	L61F	probably damaging	Het
Jak3	T	C	8: 71,685,946		probably benign	Het
Kcnn3	T	A	3: 89,609,405	C374S	probably benign	Het
Klk1b22	A	G	7: 44,116,351		probably benign	Het
Larp1	T	C	11: 58,049,938	M630T	possibly damaging	Het
Lhx5	T	A	5: 120,434,660	C115S	probably damaging	Het
Lmcd1	C	A	6: 112,328,751	T271K	probably benign	Het
Lpar1	G	A	4: 58,486,798	R158*	probably null	Het
Lyst	T	A	13: 13,647,083	C1347*	probably null	Het
Maats1	T	A	16: 38,321,419	N384Y	possibly damaging	Het
Map3k8	G	A	18: 4,332,389	Q441*	probably null	Het
Mboat1	T	C	13: 30,219,650	V144A	probably damaging	Het
Mcur1	C	T	13: 43,560,015	G38S	unknown	Het
Med13	T	A	11: 86,329,351	M276L	probably benign	Het
Mefv	A	G	16: 3,708,664	S699P	possibly damaging	Het
Mfsd4a	C	A	1: 132,059,339	A62S	probably damaging	Het
Mmp27	A	G	9: 7,571,458	M1V	probably null	Het
Myo1c	C	T	11: 75,657,589	T58I	probably damaging	Het
Myom3	A	T	4: 135,810,755	D1316V	probably benign	Het
Naa25	C	A	5: 121,420,593	R333S	probably damaging	Het
Naa25	T	A	5: 121,417,415	C235S	possibly damaging	Het
Nav3	G	A	10: 109,703,372	T2056I	probably benign	Het
Nol4	A	G	18: 22,769,821	Y378H	probably damaging	Het
Npat	G	A	9: 53,552,289	R124Q	probably damaging	Het
Npr3	T	A	15: 11,848,579	E434V	probably benign	Het
Nptx2	A	G	5: 144,548,320	T208A	probably benign	Het
Obscn	C	T	11: 59,077,780	V2798M	probably damaging	Het
Olfr1406	A	T	1: 173,184,409	H8Q	probably benign	Het
Olfr1484	C	T	19: 13,585,415	T37I	probably benign	Het
Olfr569	A	G	7: 102,888,043	Y37H	probably benign	Het
Padi1	G	A	4: 140,814,656	P652S	probably damaging	Het
Pcdh1	G	T	18: 38,198,885	P355Q	probably damaging	Het
Pck2	G	A	14: 55,543,965	R189H	possibly damaging	Het
Pcsk5	T	A	19: 17,454,750	K1500N	possibly damaging	Het
Phc3	A	T	3: 30,948,716	S218T	probably damaging	Het
Piezo2	T	A	18: 63,106,284	M510L	possibly damaging	Het
Ppp1r3a	A	T	6: 14,754,718	Y177N	probably damaging	Het
Psme2b	A	T	11: 48,945,534	D195E	probably damaging	Het
Ptprr	T	C	10: 116,252,922	V463A	probably damaging	Het
Pwwp2b	G	A	7: 139,256,365	R574Q	probably damaging	Het
Rap1gds1	T	A	3: 139,050,553	T14S	possibly damaging	Het
Rbm11	A	T	16: 75,600,797	K205M	probably damaging	Het
Rfx1	T	A	8: 84,066,421		probably benign	Het
Rnasel	C	A	1: 153,754,423	H228Q	probably damaging	Het
Sap130	T	A	18: 31,698,587	I710K	probably benign	Het
Slc27a4	C	A	2: 29,805,721	D89E	probably benign	Het
Spata31d1b	T	C	13: 59,715,965	V309A	probably benign	Het
Syt7	T	G	19: 10,443,990	Y420D	probably damaging	Het
Tanc2	A	G	11: 105,625,033		probably null	Het
Tbc1d10b	A	G	7: 127,203,758	S333P	possibly damaging	Het
Tenm2	G	A	11: 36,023,382	P2442S	probably damaging	Het
Timmdc1	A	G	16: 38,499,057	L245P	possibly damaging	Het
Tlr5	T	C	1: 182,972,447	F5L	probably benign	Het
Ttc25	C	A	11: 100,569,853		probably null	Het
Ttll4	T	A	1: 74,687,840	F784L	possibly damaging	Het
Tulp4	A	G	17: 6,139,112	T70A	possibly damaging	Het
Txndc17	T	A	11: 72,208,745	N81K	probably benign	Het
Ubr3	C	T	2: 70,000,551		probably benign	Het
Uri1	A	C	7: 37,981,691	V96G	probably damaging	Het
Uspl1	T	A	5: 149,213,436	I482N	probably damaging	Het
Vmn1r229	A	G	17: 20,814,712	N73S	possibly damaging	Het
Vwa7	G	T	17: 35,024,412	G689*	probably null	Het
Zfp114	T	A	7: 24,177,739		probably null	Het
Zfp618	A	G	4: 63,133,237	S659G	probably damaging	Het
Zfp872	A	G	9: 22,200,053	K275R	probably damaging	Het
Zzef1	C	T	11: 72,886,709	P1789S	probably damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,417,060 (GRCm38)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,236,025 (GRCm38)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,279,042 (GRCm38)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,276,421 (GRCm38)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,417,132 (GRCm38)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,256,841 (GRCm38)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,236,423 (GRCm38)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,276,645 (GRCm38)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,228,802 (GRCm38)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,254,477 (GRCm38)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,236,758 (GRCm38)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,276,396 (GRCm38)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,276,576 (GRCm38)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,235,476 (GRCm38)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,236,694 (GRCm38)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,279,198 (GRCm38)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,288,016 (GRCm38)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,299,639 (GRCm38)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,298,956 (GRCm38)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,276,903 (GRCm38)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,298,878 (GRCm38)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	48,646,418 (GRCm38)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,235,523 (GRCm38)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,235,346 (GRCm38)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,235,607 (GRCm38)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,293,657 (GRCm38)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,343,345 (GRCm38)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,342,659 (GRCm38)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	48,674,472 (GRCm38)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,236,720 (GRCm38)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,341,034 (GRCm38)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,236,912 (GRCm38)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,232,105 (GRCm38)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,228,975 (GRCm38)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,287,791 (GRCm38)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,341,160 (GRCm38)	splice site	probably benign
R0573:Tenm3	UTSW	8	48,674,399 (GRCm38)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,277,710 (GRCm38)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,276,156 (GRCm38)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,236,525 (GRCm38)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,236,594 (GRCm38)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,335,742 (GRCm38)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,298,965 (GRCm38)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,228,542 (GRCm38)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,235,582 (GRCm38)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,240,396 (GRCm38)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,287,893 (GRCm38)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,276,400 (GRCm38)	missense	probably benign
R1455:Tenm3	UTSW	8	48,279,048 (GRCm38)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,235,971 (GRCm38)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,310,625 (GRCm38)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,343,316 (GRCm38)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,287,822 (GRCm38)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,395,576 (GRCm38)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,228,981 (GRCm38)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,236,421 (GRCm38)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,228,993 (GRCm38)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,279,074 (GRCm38)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,417,119 (GRCm38)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,310,634 (GRCm38)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,232,104 (GRCm38)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,417,179 (GRCm38)	missense	probably benign	0.05
R1801:Tenm3	UTSW	8	48,276,256 (GRCm38)	missense	probably benign	0.39
R1863:Tenm3	UTSW	8	48,276,346 (GRCm38)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,310,761 (GRCm38)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,236,313 (GRCm38)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,228,591 (GRCm38)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,228,668 (GRCm38)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,342,256 (GRCm38)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,343,349 (GRCm38)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,417,006 (GRCm38)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,395,544 (GRCm38)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	48,674,550 (GRCm38)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,276,169 (GRCm38)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,342,337 (GRCm38)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,276,658 (GRCm38)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,287,953 (GRCm38)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,240,270 (GRCm38)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,228,555 (GRCm38)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,277,746 (GRCm38)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,349,223 (GRCm38)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,349,404 (GRCm38)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,395,658 (GRCm38)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,293,726 (GRCm38)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,235,970 (GRCm38)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,310,621 (GRCm38)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,235,821 (GRCm38)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,276,861 (GRCm38)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,300,971 (GRCm38)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,278,961 (GRCm38)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,229,137 (GRCm38)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,235,826 (GRCm38)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,342,308 (GRCm38)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,229,198 (GRCm38)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,236,855 (GRCm38)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,287,831 (GRCm38)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,236,355 (GRCm38)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,236,564 (GRCm38)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,367,377 (GRCm38)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,279,006 (GRCm38)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,236,764 (GRCm38)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,228,762 (GRCm38)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	48,646,498 (GRCm38)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	48,646,447 (GRCm38)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,228,508 (GRCm38)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,343,406 (GRCm38)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,395,573 (GRCm38)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,298,808 (GRCm38)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,254,622 (GRCm38)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,293,665 (GRCm38)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,417,059 (GRCm38)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,367,394 (GRCm38)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,276,849 (GRCm38)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,236,063 (GRCm38)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6516:Tenm3	UTSW	8	48,417,222 (GRCm38)	missense	probably benign
R6747:Tenm3	UTSW	8	48,343,243 (GRCm38)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	48,646,256 (GRCm38)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	48,674,493 (GRCm38)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,256,837 (GRCm38)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,276,738 (GRCm38)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	48,674,416 (GRCm38)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,240,479 (GRCm38)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,236,439 (GRCm38)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,240,444 (GRCm38)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	48,674,553 (GRCm38)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,292,236 (GRCm38)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,300,969 (GRCm38)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,235,935 (GRCm38)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,236,177 (GRCm38)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,236,183 (GRCm38)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,287,812 (GRCm38)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,276,600 (GRCm38)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,341,049 (GRCm38)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,335,727 (GRCm38)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	48,646,333 (GRCm38)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,236,465 (GRCm38)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,276,300 (GRCm38)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,229,111 (GRCm38)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,310,703 (GRCm38)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,367,422 (GRCm38)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,293,773 (GRCm38)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,287,848 (GRCm38)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,293,509 (GRCm38)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,287,872 (GRCm38)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,229,181 (GRCm38)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,342,633 (GRCm38)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,299,645 (GRCm38)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,349,356 (GRCm38)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,342,449 (GRCm38)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,310,724 (GRCm38)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8831:Tenm3	UTSW	8	48,276,382 (GRCm38)	missense
R8853:Tenm3	UTSW	8	48,342,347 (GRCm38)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,236,402 (GRCm38)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,235,602 (GRCm38)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,279,060 (GRCm38)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,235,348 (GRCm38)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,276,687 (GRCm38)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,342,653 (GRCm38)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,254,633 (GRCm38)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,292,151 (GRCm38)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,313,236 (GRCm38)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,335,513 (GRCm38)	missense	unknown
R9231:Tenm3	UTSW	8	48,236,196 (GRCm38)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,298,937 (GRCm38)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	48,555,900 (GRCm38)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,417,080 (GRCm38)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,299,655 (GRCm38)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	48,674,524 (GRCm38)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,313,257 (GRCm38)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,235,761 (GRCm38)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,236,211 (GRCm38)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,300,814 (GRCm38)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,335,561 (GRCm38)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,287,829 (GRCm38)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,236,477 (GRCm38)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,276,780 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TAAGAACGCGTGCGGATACC -3'
(R):5'- TGCTTTCGCTGACGTCATG -3'

Sequencing Primer
(F):5'- CGGATACCTTGTTCTACTAGAGCG -3'
(R):5'- TCGCTGACGTCATGCCAAC -3'

Posted On

2014-06-23