Mutagenetix > Incidental Mutation

Incidental Mutation 'R1794:Hmcn1'

202013

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

LOC240793, EG545370

MMRRC Submission

039824-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1794 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

150562524-150993435 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 150627152 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Isoleucine at position 3908 (T3908I)

Ref Sequence

ENSEMBL: ENSMUSP00000121500 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000074783
AA Change: T3908I

PolyPhen 2 Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: T3908I

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably damaging
Transcript: ENSMUST00000137197
AA Change: T3908I

PolyPhen 2 Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: T3908I

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177239

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177268

Coding Region Coverage

1x: 97.4%
3x: 96.7%
10x: 94.8%
20x: 91.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700014D04Rik	T	C	13: 59,742,620 (GRCm38)	E44G	probably benign	Het
Anxa7	A	G	14: 20,471,467 (GRCm38)	Y54H	unknown	Het
Arhgef3	A	G	14: 27,397,605 (GRCm38)	T331A	probably benign	Het
Arhgef40	G	T	14: 51,989,930 (GRCm38)	C477F	possibly damaging	Het
Arsi	G	A	18: 60,916,651 (GRCm38)	G202E	probably benign	Het
Atp13a5	C	A	16: 29,321,709 (GRCm38)	R343L	probably damaging	Het
Brdt	ACAGCAGCAGCAGCAGC	ACAGCAGCAGCAGC	5: 107,359,853 (GRCm38)		probably benign	Het
Btbd2	G	T	10: 80,643,913 (GRCm38)	D426E	probably damaging	Het
Cabin1	A	C	10: 75,725,745 (GRCm38)	I974R	possibly damaging	Het
Cacna1i	G	A	15: 80,389,122 (GRCm38)	V1670M	probably damaging	Het
Cc2d2a	C	A	5: 43,688,252 (GRCm38)	Q288K	probably damaging	Het
Ccl20	T	A	1: 83,117,829 (GRCm38)	I37K	possibly damaging	Het
Cdcp1	T	C	9: 123,215,831 (GRCm38)	T27A	probably benign	Het
Cdcp1	A	G	9: 123,190,094 (GRCm38)	V40A	probably benign	Het
Cdh4	C	T	2: 179,886,842 (GRCm38)	T581I	probably damaging	Het
Cgn	A	G	3: 94,762,557 (GRCm38)		probably null	Het
Col7a1	G	A	9: 108,965,928 (GRCm38)	G1493D	unknown	Het
Creb3	A	G	4: 43,563,302 (GRCm38)	E133G	probably benign	Het
Dchs1	T	C	7: 105,771,720 (GRCm38)	T498A	probably benign	Het
Dis3l	A	C	9: 64,317,776 (GRCm38)	V413G	possibly damaging	Het
Dnah6	T	C	6: 73,024,958 (GRCm38)	E3865G	probably damaging	Het
Fam219b	A	G	9: 57,539,281 (GRCm38)	Y139C	probably damaging	Het
Fat3	A	T	9: 15,997,136 (GRCm38)	Y2523*	probably null	Het
Fat3	A	T	9: 15,997,138 (GRCm38)	Y2523N	probably benign	Het
Fmnl1	T	C	11: 103,197,147 (GRCm38)	S40P	probably benign	Het
Gm17727	T	A	9: 35,777,122 (GRCm38)	I56F	probably benign	Het
Gm4792	T	C	10: 94,298,490 (GRCm38)	D6G	unknown	Het
Hhat	G	T	1: 192,693,906 (GRCm38)	Y306*	probably null	Het
Hsph1	A	T	5: 149,630,773 (GRCm38)	N79K	probably damaging	Het
Ikbke	T	A	1: 131,259,218 (GRCm38)	Y579F	probably damaging	Het
Jak2	A	G	19: 29,299,557 (GRCm38)	D838G	probably benign	Het
Klhdc7b	T	C	15: 89,387,020 (GRCm38)	S702P	probably benign	Het
Lingo3	C	A	10: 80,835,598 (GRCm38)	R166L	probably benign	Het
Lins1	T	C	7: 66,711,909 (GRCm38)	F436S	probably damaging	Het
Lman1	T	C	18: 65,991,684 (GRCm38)	D328G	probably benign	Het
Lox	A	G	18: 52,528,307 (GRCm38)	C232R	probably damaging	Het
Lrrc59	T	C	11: 94,638,595 (GRCm38)	V165A	probably benign	Het
Map9	A	G	3: 82,380,221 (GRCm38)	D50G	probably damaging	Het
March1	T	A	8: 66,386,942 (GRCm38)	Y126N	possibly damaging	Het
Mcf2l	T	C	8: 12,915,982 (GRCm38)	F3L	probably benign	Het
Mslnl	G	A	17: 25,742,934 (GRCm38)	V128M	probably damaging	Het
Nin	G	A	12: 70,043,795 (GRCm38)	Q949*	probably null	Het
Nlgn3	A	G	X: 101,320,033 (GRCm38)	H636R	probably benign	Het
Notch2	A	G	3: 98,099,547 (GRCm38)	D411G	possibly damaging	Het
Olfr1263	A	G	2: 90,015,020 (GRCm38)	Y30C	probably damaging	Het
Olfr1449	G	C	19: 12,934,968 (GRCm38)	A77P	probably damaging	Het
Plekha7	A	G	7: 116,140,681 (GRCm38)	V579A	probably damaging	Het
Prrc2c	T	C	1: 162,705,959 (GRCm38)		probably benign	Het
Rab7b	T	C	1: 131,697,068 (GRCm38)		probably null	Het
Reg3b	G	T	6: 78,372,214 (GRCm38)		probably null	Het
Rgs20	A	G	1: 4,910,572 (GRCm38)	Y177H	probably damaging	Het
Ripk3	G	T	14: 55,785,329 (GRCm38)	N379K	probably benign	Het
Rnf220	G	T	4: 117,307,568 (GRCm38)	Q7K	probably benign	Het
Ros1	T	A	10: 52,124,103 (GRCm38)	K1109*	probably null	Het
Slc22a7	T	G	17: 46,433,153 (GRCm38)	R460S	probably damaging	Het
Slc4a2	A	G	5: 24,439,328 (GRCm38)	M975V	probably damaging	Het
Slc4a3	A	T	1: 75,557,308 (GRCm38)	I1100F	probably damaging	Het
Smco1	A	G	16: 32,274,132 (GRCm38)	E207G	probably benign	Het
Snrnp200	A	G	2: 127,216,736 (GRCm38)	E369G	probably benign	Het
Tcf4	T	A	18: 69,657,853 (GRCm38)	M178K	probably benign	Het
Tex2	T	C	11: 106,567,902 (GRCm38)		probably benign	Het
Tjp1	A	T	7: 65,323,129 (GRCm38)	I521N	probably damaging	Het
Tmem203	A	G	2: 25,255,994 (GRCm38)	T109A	probably benign	Het
Tmem50b	T	C	16: 91,578,029 (GRCm38)	I126V	probably benign	Het
Ugcg	C	T	4: 59,207,798 (GRCm38)	P46S	probably benign	Het
Ush2a	T	C	1: 188,862,809 (GRCm38)	F3813L	probably benign	Het
Vmn1r203	C	T	13: 22,524,351 (GRCm38)	R101W	probably damaging	Het
Vmn2r79	G	A	7: 87,001,413 (GRCm38)	V136I	probably benign	Het
Wdr38	A	G	2: 39,000,729 (GRCm38)	Y205C	probably damaging	Het
Zfp248	A	G	6: 118,429,303 (GRCm38)	F442L	probably damaging	Het
Znrf4	A	G	17: 56,511,599 (GRCm38)	I236T	probably damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,677,278 (GRCm38)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,638,999 (GRCm38)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,806,366 (GRCm38)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,664,936 (GRCm38)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,656,734 (GRCm38)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,630,340 (GRCm38)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,610,713 (GRCm38)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,605,006 (GRCm38)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,582,301 (GRCm38)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,638,869 (GRCm38)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,627,033 (GRCm38)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,632,552 (GRCm38)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,622,924 (GRCm38)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,745,001 (GRCm38)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,719,240 (GRCm38)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,593,097 (GRCm38)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,859,239 (GRCm38)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,605,072 (GRCm38)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,609,631 (GRCm38)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,598,397 (GRCm38)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,627,413 (GRCm38)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,672,032 (GRCm38)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,580,233 (GRCm38)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,737,299 (GRCm38)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,583,280 (GRCm38)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,744,960 (GRCm38)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,672,038 (GRCm38)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,615,300 (GRCm38)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,690,601 (GRCm38)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,742,260 (GRCm38)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,667,887 (GRCm38)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,732,892 (GRCm38)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,603,871 (GRCm38)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,615,298 (GRCm38)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,704,181 (GRCm38)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,630,728 (GRCm38)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,722,607 (GRCm38)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,563,598 (GRCm38)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,806,401 (GRCm38)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,664,915 (GRCm38)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,802,897 (GRCm38)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,722,424 (GRCm38)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,993,023 (GRCm38)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,809,726 (GRCm38)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,697,493 (GRCm38)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,744,995 (GRCm38)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,619,009 (GRCm38)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,604,903 (GRCm38)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,656,694 (GRCm38)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,646,832 (GRCm38)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,563,828 (GRCm38)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,675,974 (GRCm38)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,577,278 (GRCm38)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,657,207 (GRCm38)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,697,522 (GRCm38)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,671,917 (GRCm38)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,808,539 (GRCm38)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,802,909 (GRCm38)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,743,667 (GRCm38)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,770,352 (GRCm38)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,772,510 (GRCm38)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,598,424 (GRCm38)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,630,231 (GRCm38)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,732,910 (GRCm38)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,701,969 (GRCm38)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,663,872 (GRCm38)	missense	probably damaging	1.00
Backbone	UTSW	1	150,622,994 (GRCm38)	missense	probably benign	0.09
Cambrian	UTSW	1	150,732,846 (GRCm38)	missense	probably damaging	1.00
chordate	UTSW	1	150,587,015 (GRCm38)	missense	probably benign	0.00
Justamere	UTSW	1	150,588,257 (GRCm38)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,675,540 (GRCm38)	missense	probably benign	0.00
notochord	UTSW	1	150,770,293 (GRCm38)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,732,946 (GRCm38)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,738,658 (GRCm38)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,720,689 (GRCm38)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,808,737 (GRCm38)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,669,487 (GRCm38)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,808,676 (GRCm38)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,652,551 (GRCm38)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,677,406 (GRCm38)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,587,015 (GRCm38)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,808,647 (GRCm38)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,677,324 (GRCm38)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,663,879 (GRCm38)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,603,811 (GRCm38)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,798,814 (GRCm38)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,715,822 (GRCm38)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,732,792 (GRCm38)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,859,252 (GRCm38)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,876,419 (GRCm38)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,742,341 (GRCm38)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,719,117 (GRCm38)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,650,017 (GRCm38)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,609,801 (GRCm38)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,657,376 (GRCm38)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,594,016 (GRCm38)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,798,719 (GRCm38)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,819,410 (GRCm38)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,808,787 (GRCm38)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,753,665 (GRCm38)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,650,073 (GRCm38)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,577,377 (GRCm38)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,618,928 (GRCm38)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,618,928 (GRCm38)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,679,607 (GRCm38)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,749,026 (GRCm38)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,753,654 (GRCm38)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,748,191 (GRCm38)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,586,468 (GRCm38)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,680,715 (GRCm38)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,646,794 (GRCm38)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,652,506 (GRCm38)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,609,700 (GRCm38)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,689,590 (GRCm38)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,772,552 (GRCm38)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,669,421 (GRCm38)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,773,803 (GRCm38)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,734,532 (GRCm38)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,657,241 (GRCm38)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,745,027 (GRCm38)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,669,558 (GRCm38)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,630,333 (GRCm38)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,565,369 (GRCm38)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,675,984 (GRCm38)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,859,186 (GRCm38)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,586,468 (GRCm38)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,599,030 (GRCm38)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,563,568 (GRCm38)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,749,083 (GRCm38)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,598,285 (GRCm38)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,721,664 (GRCm38)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,657,193 (GRCm38)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,603,812 (GRCm38)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,720,695 (GRCm38)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,638,900 (GRCm38)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,577,295 (GRCm38)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,819,500 (GRCm38)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,819,500 (GRCm38)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,657,451 (GRCm38)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,992,855 (GRCm38)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,604,882 (GRCm38)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,649,676 (GRCm38)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,677,376 (GRCm38)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,675,991 (GRCm38)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,738,613 (GRCm38)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,677,334 (GRCm38)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,577,323 (GRCm38)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,633,659 (GRCm38)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,715,815 (GRCm38)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,599,010 (GRCm38)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,624,598 (GRCm38)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,704,226 (GRCm38)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,652,678 (GRCm38)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,622,934 (GRCm38)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,565,384 (GRCm38)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,860,341 (GRCm38)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,599,032 (GRCm38)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,615,221 (GRCm38)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,686,867 (GRCm38)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,773,820 (GRCm38)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,743,647 (GRCm38)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,652,575 (GRCm38)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,630,652 (GRCm38)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,563,599 (GRCm38)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,563,599 (GRCm38)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,738,716 (GRCm38)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,802,873 (GRCm38)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,749,035 (GRCm38)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,605,102 (GRCm38)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,605,102 (GRCm38)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,689,518 (GRCm38)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,745,025 (GRCm38)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,802,824 (GRCm38)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,622,994 (GRCm38)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,586,418 (GRCm38)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,649,577 (GRCm38)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,586,965 (GRCm38)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,635,195 (GRCm38)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,690,610 (GRCm38)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,573,569 (GRCm38)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,722,453 (GRCm38)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,722,369 (GRCm38)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,772,502 (GRCm38)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,703,216 (GRCm38)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,658,508 (GRCm38)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,595,999 (GRCm38)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,657,459 (GRCm38)	missense	probably null
R4493:Hmcn1	UTSW	1	150,701,899 (GRCm38)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,633,666 (GRCm38)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,563,780 (GRCm38)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,734,487 (GRCm38)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,738,645 (GRCm38)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,595,894 (GRCm38)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,675,511 (GRCm38)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,624,550 (GRCm38)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,619,065 (GRCm38)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,772,571 (GRCm38)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,694,833 (GRCm38)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,689,595 (GRCm38)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,577,612 (GRCm38)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,753,611 (GRCm38)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,753,611 (GRCm38)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,593,085 (GRCm38)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,677,379 (GRCm38)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,722,535 (GRCm38)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,876,360 (GRCm38)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,657,470 (GRCm38)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,819,449 (GRCm38)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,680,688 (GRCm38)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,588,257 (GRCm38)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,737,256 (GRCm38)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,610,669 (GRCm38)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,656,741 (GRCm38)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,646,701 (GRCm38)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,595,861 (GRCm38)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,679,514 (GRCm38)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,582,296 (GRCm38)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,755,372 (GRCm38)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,623,244 (GRCm38)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,701,972 (GRCm38)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,675,540 (GRCm38)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,609,825 (GRCm38)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,743,788 (GRCm38)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,755,291 (GRCm38)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,737,506 (GRCm38)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,577,539 (GRCm38)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,656,567 (GRCm38)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,658,562 (GRCm38)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,609,778 (GRCm38)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,690,600 (GRCm38)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,609,666 (GRCm38)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,694,849 (GRCm38)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,758,474 (GRCm38)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,808,697 (GRCm38)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,573,554 (GRCm38)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,694,878 (GRCm38)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,674,347 (GRCm38)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,649,607 (GRCm38)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,737,524 (GRCm38)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,993,023 (GRCm38)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,630,327 (GRCm38)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,598,897 (GRCm38)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,577,296 (GRCm38)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,657,222 (GRCm38)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,563,817 (GRCm38)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,704,173 (GRCm38)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,802,895 (GRCm38)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,632,437 (GRCm38)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,663,909 (GRCm38)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,770,330 (GRCm38)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,755,294 (GRCm38)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,755,293 (GRCm38)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,631,227 (GRCm38)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,618,936 (GRCm38)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,732,846 (GRCm38)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,722,424 (GRCm38)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,565,425 (GRCm38)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,646,784 (GRCm38)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,615,438 (GRCm38)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,630,728 (GRCm38)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,738,681 (GRCm38)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,697,419 (GRCm38)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,697,476 (GRCm38)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,744,960 (GRCm38)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,703,216 (GRCm38)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,992,919 (GRCm38)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,664,784 (GRCm38)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,677,302 (GRCm38)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,583,278 (GRCm38)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,697,566 (GRCm38)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,615,438 (GRCm38)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,595,118 (GRCm38)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,723,257 (GRCm38)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,743,796 (GRCm38)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,758,306 (GRCm38)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,745,033 (GRCm38)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,704,175 (GRCm38)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,734,518 (GRCm38)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,770,293 (GRCm38)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,993,051 (GRCm38)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,599,653 (GRCm38)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,773,890 (GRCm38)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,604,102 (GRCm38)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,860,367 (GRCm38)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,604,246 (GRCm38)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,700,541 (GRCm38)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,577,210 (GRCm38)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,663,873 (GRCm38)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,686,854 (GRCm38)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,748,993 (GRCm38)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,753,699 (GRCm38)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,649,580 (GRCm38)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,638,876 (GRCm38)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,722,643 (GRCm38)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,715,823 (GRCm38)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,582,337 (GRCm38)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,683,715 (GRCm38)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,733,129 (GRCm38)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,732,946 (GRCm38)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,603,814 (GRCm38)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,638,866 (GRCm38)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,683,745 (GRCm38)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,667,889 (GRCm38)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,806,445 (GRCm38)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,618,846 (GRCm38)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,563,631 (GRCm38)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,646,670 (GRCm38)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,674,430 (GRCm38)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,720,759 (GRCm38)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,630,266 (GRCm38)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,563,604 (GRCm38)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,580,267 (GRCm38)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,677,234 (GRCm38)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,622,967 (GRCm38)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,656,573 (GRCm38)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,686,780 (GRCm38)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,604,874 (GRCm38)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,655,835 (GRCm38)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,657,134 (GRCm38)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,565,329 (GRCm38)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,646,709 (GRCm38)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,667,880 (GRCm38)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,722,445 (GRCm38)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,756,592 (GRCm38)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,770,279 (GRCm38)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,806,421 (GRCm38)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,744,971 (GRCm38)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,657,470 (GRCm38)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,593,189 (GRCm38)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,664,892 (GRCm38)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,609,775 (GRCm38)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,650,084 (GRCm38)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,655,855 (GRCm38)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,664,878 (GRCm38)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,598,311 (GRCm38)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,649,992 (GRCm38)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,656,505 (GRCm38)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,749,090 (GRCm38)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,859,206 (GRCm38)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,753,660 (GRCm38)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,604,954 (GRCm38)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,646,658 (GRCm38)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,722,514 (GRCm38)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,577,477 (GRCm38)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,594,010 (GRCm38)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,819,366 (GRCm38)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,859,254 (GRCm38)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,738,764 (GRCm38)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,738,734 (GRCm38)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,758,391 (GRCm38)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,694,920 (GRCm38)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,603,800 (GRCm38)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,580,239 (GRCm38)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,573,551 (GRCm38)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,676,038 (GRCm38)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,755,257 (GRCm38)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,633,620 (GRCm38)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,680,662 (GRCm38)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,664,885 (GRCm38)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,715,718 (GRCm38)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,734,497 (GRCm38)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,655,819 (GRCm38)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,671,975 (GRCm38)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,638,908 (GRCm38)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,649,972 (GRCm38)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,773,779 (GRCm38)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,755,044 (GRCm38)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,817,119 (GRCm38)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,689,569 (GRCm38)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,756,558 (GRCm38)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,657,118 (GRCm38)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,697,580 (GRCm38)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,598,390 (GRCm38)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,646,592 (GRCm38)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,630,341 (GRCm38)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,624,586 (GRCm38)	nonsense	probably null
R9182:Hmcn1	UTSW	1	150,612,654 (GRCm38)	missense	probably damaging	1.00
R9204:Hmcn1	UTSW	1	150,734,511 (GRCm38)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,719,093 (GRCm38)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,597,989 (GRCm38)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,756,558 (GRCm38)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,630,295 (GRCm38)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,646,592 (GRCm38)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,669,436 (GRCm38)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,630,302 (GRCm38)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,723,497 (GRCm38)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,630,720 (GRCm38)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,586,376 (GRCm38)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,734,530 (GRCm38)	missense	probably benign	0.06
R9496:Hmcn1	UTSW	1	150,704,220 (GRCm38)	missense	probably benign	0.00
R9501:Hmcn1	UTSW	1	150,595,239 (GRCm38)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,586,376 (GRCm38)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,669,424 (GRCm38)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,622,909 (GRCm38)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,599,552 (GRCm38)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,679,595 (GRCm38)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,808,722 (GRCm38)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,630,303 (GRCm38)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,743,741 (GRCm38)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,737,605 (GRCm38)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,609,627 (GRCm38)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,798,815 (GRCm38)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,748,190 (GRCm38)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,756,588 (GRCm38)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,992,874 (GRCm38)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,722,629 (GRCm38)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,652,582 (GRCm38)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,732,938 (GRCm38)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,808,640 (GRCm38)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,624,561 (GRCm38)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,635,146 (GRCm38)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,700,530 (GRCm38)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,860,376 (GRCm38)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,663,901 (GRCm38)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,648,937 (GRCm38)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,663,917 (GRCm38)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,655,921 (GRCm38)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,586,445 (GRCm38)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- AACTACTCCAGTCAGTGAGAGTG -3'
(R):5'- ACTGTCCAAGGTAGAACAAGCC -3'

Sequencing Primer
(F):5'- TCCAGTCAGTGAGAGTGCAGTC -3'
(R):5'- TGAGGGACACACAATGCTGTCC -3'

Posted On

2014-06-23