Incidental Mutation 'R1795:Atrn'
| ID |
202105 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
039825-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1795 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
130906495-131030333 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 130972288 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 718
(D718G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028781
AA Change: D718G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: D718G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 100 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931408C20Rik |
C |
A |
1: 26,682,989 (GRCm38) |
G1037* |
probably null |
Het |
| Abca8a |
A |
G |
11: 110,050,966 (GRCm38) |
I1159T |
probably benign |
Het |
| Abcc1 |
T |
C |
16: 14,465,137 (GRCm38) |
V1159A |
possibly damaging |
Het |
| Abcg5 |
A |
G |
17: 84,673,579 (GRCm38) |
I194T |
probably damaging |
Het |
| Abtb2 |
A |
G |
2: 103,567,024 (GRCm38) |
T100A |
probably benign |
Het |
| Adam4 |
C |
T |
12: 81,421,294 (GRCm38) |
M184I |
probably benign |
Het |
| Afap1l2 |
T |
C |
19: 56,928,409 (GRCm38) |
D155G |
probably damaging |
Het |
| Ahnak |
T |
C |
19: 9,002,438 (GRCm38) |
V362A |
possibly damaging |
Het |
| Ak7 |
C |
T |
12: 105,726,223 (GRCm38) |
R179* |
probably null |
Het |
| Akap8 |
C |
A |
17: 32,315,477 (GRCm38) |
G332C |
probably damaging |
Het |
| Akr1e1 |
T |
A |
13: 4,595,072 (GRCm38) |
Q204L |
probably damaging |
Het |
| Ankrd12 |
T |
C |
17: 65,986,227 (GRCm38) |
E737G |
possibly damaging |
Het |
| Bco2 |
A |
G |
9: 50,541,169 (GRCm38) |
S200P |
possibly damaging |
Het |
| C030005K15Rik |
A |
T |
10: 97,725,786 (GRCm38) |
S28T |
unknown |
Het |
| Cdc14a |
T |
A |
3: 116,298,473 (GRCm38) |
Q356L |
possibly damaging |
Het |
| Cdk5rap3 |
A |
G |
11: 96,908,828 (GRCm38) |
L387P |
probably damaging |
Het |
| Celsr1 |
A |
T |
15: 86,030,323 (GRCm38) |
S1150T |
probably damaging |
Het |
| Cntfr |
A |
G |
4: 41,670,841 (GRCm38) |
|
probably null |
Het |
| Cramp1l |
T |
C |
17: 24,964,910 (GRCm38) |
N1244D |
probably damaging |
Het |
| Csmd3 |
G |
T |
15: 47,857,920 (GRCm38) |
D1542E |
possibly damaging |
Het |
| Cyp4f17 |
A |
T |
17: 32,517,969 (GRCm38) |
I92F |
probably benign |
Het |
| Dhx30 |
A |
T |
9: 110,107,983 (GRCm38) |
|
probably null |
Het |
| Dlg1 |
T |
A |
16: 31,743,147 (GRCm38) |
H120Q |
probably benign |
Het |
| Dmgdh |
A |
T |
13: 93,706,699 (GRCm38) |
M348L |
probably benign |
Het |
| Dnmt3b |
G |
A |
2: 153,683,639 (GRCm38) |
E741K |
possibly damaging |
Het |
| Dock3 |
T |
G |
9: 107,025,335 (GRCm38) |
H292P |
probably damaging |
Het |
| Elmsan1 |
A |
G |
12: 84,158,974 (GRCm38) |
|
probably null |
Het |
| Ercc6 |
T |
A |
14: 32,517,028 (GRCm38) |
N24K |
probably benign |
Het |
| Esco2 |
T |
C |
14: 65,827,277 (GRCm38) |
Q338R |
probably benign |
Het |
| Etl4 |
T |
C |
2: 20,808,026 (GRCm38) |
|
probably null |
Het |
| Exoc7 |
A |
T |
11: 116,292,521 (GRCm38) |
I498N |
probably damaging |
Het |
| Fap |
G |
A |
2: 62,548,589 (GRCm38) |
S123L |
probably damaging |
Het |
| Foxn1 |
T |
C |
11: 78,371,225 (GRCm38) |
E106G |
probably benign |
Het |
| Fscb |
T |
A |
12: 64,474,401 (GRCm38) |
D97V |
probably damaging |
Het |
| Gabrg1 |
T |
C |
5: 70,782,253 (GRCm38) |
T174A |
possibly damaging |
Het |
| Gan |
C |
T |
8: 117,196,460 (GRCm38) |
A461V |
possibly damaging |
Het |
| Gbp2 |
T |
A |
3: 142,630,523 (GRCm38) |
D211E |
possibly damaging |
Het |
| Gm10271 |
A |
T |
10: 116,956,841 (GRCm38) |
Y47N |
unknown |
Het |
| Gm17333 |
G |
T |
16: 77,852,823 (GRCm38) |
|
noncoding transcript |
Het |
| Gm1758 |
T |
A |
16: 14,502,278 (GRCm38) |
|
noncoding transcript |
Het |
| Golga3 |
A |
G |
5: 110,207,627 (GRCm38) |
K989R |
possibly damaging |
Het |
| Gucy2g |
C |
A |
19: 55,199,541 (GRCm38) |
V1041F |
probably damaging |
Het |
| Guk1 |
A |
T |
11: 59,186,813 (GRCm38) |
F25I |
probably benign |
Het |
| H2al1o |
C |
T |
X: 9,572,090 (GRCm38) |
E87K |
possibly damaging |
Het |
| Hemgn |
C |
A |
4: 46,395,958 (GRCm38) |
C426F |
probably damaging |
Het |
| Hps3 |
A |
G |
3: 20,012,695 (GRCm38) |
|
probably null |
Het |
| Il2rb |
A |
T |
15: 78,483,987 (GRCm38) |
D287E |
probably damaging |
Het |
| Ino80 |
A |
T |
2: 119,406,859 (GRCm38) |
V1123D |
probably damaging |
Het |
| Kdm2b |
A |
G |
5: 122,984,460 (GRCm38) |
|
probably null |
Het |
| Kif21a |
A |
T |
15: 90,972,727 (GRCm38) |
|
probably null |
Het |
| Klhl33 |
A |
T |
14: 50,892,126 (GRCm38) |
N347K |
probably damaging |
Het |
| Krt2 |
A |
G |
15: 101,816,426 (GRCm38) |
F250L |
possibly damaging |
Het |
| Krt82 |
T |
A |
15: 101,543,384 (GRCm38) |
N332I |
possibly damaging |
Het |
| Lgi1 |
A |
G |
19: 38,306,183 (GRCm38) |
I444V |
probably benign |
Het |
| Lmod1 |
G |
A |
1: 135,325,124 (GRCm38) |
V39M |
probably damaging |
Het |
| Lonrf2 |
G |
A |
1: 38,813,276 (GRCm38) |
P165S |
probably benign |
Het |
| Mex3d |
T |
C |
10: 80,381,542 (GRCm38) |
T149A |
probably benign |
Het |
| Mlxipl |
A |
C |
5: 135,107,170 (GRCm38) |
D83A |
probably damaging |
Het |
| Mroh8 |
T |
A |
2: 157,269,551 (GRCm38) |
E161V |
probably benign |
Het |
| Mroh9 |
G |
A |
1: 163,056,778 (GRCm38) |
T397I |
probably damaging |
Het |
| Mtss1 |
T |
C |
15: 59,058,400 (GRCm38) |
D32G |
possibly damaging |
Het |
| Mus81 |
T |
C |
19: 5,483,476 (GRCm38) |
D495G |
probably benign |
Het |
| Neurod1 |
A |
C |
2: 79,454,329 (GRCm38) |
S237A |
probably benign |
Het |
| Npas1 |
G |
A |
7: 16,474,800 (GRCm38) |
R51C |
probably damaging |
Het |
| Olfr743 |
T |
C |
14: 50,533,702 (GRCm38) |
S97P |
possibly damaging |
Het |
| P2ry14 |
T |
C |
3: 59,115,853 (GRCm38) |
N62S |
probably damaging |
Het |
| Pcdh15 |
A |
G |
10: 74,624,255 (GRCm38) |
Y1308C |
probably damaging |
Het |
| Pcdhb14 |
A |
T |
18: 37,449,535 (GRCm38) |
M565L |
probably benign |
Het |
| Pde6a |
A |
G |
18: 61,257,212 (GRCm38) |
E502G |
probably damaging |
Het |
| Pde8b |
A |
G |
13: 95,042,019 (GRCm38) |
V566A |
probably benign |
Het |
| Phf11b |
G |
T |
14: 59,328,105 (GRCm38) |
Q108K |
probably benign |
Het |
| Pikfyve |
T |
C |
1: 65,252,557 (GRCm38) |
Y1312H |
probably damaging |
Het |
| Plcb3 |
T |
C |
19: 6,956,013 (GRCm38) |
|
probably benign |
Het |
| Plxna2 |
G |
A |
1: 194,806,303 (GRCm38) |
G1629D |
probably damaging |
Het |
| Plxnb1 |
T |
C |
9: 109,100,745 (GRCm38) |
V223A |
probably benign |
Het |
| Prkca |
A |
T |
11: 108,012,692 (GRCm38) |
Y285N |
possibly damaging |
Het |
| Prl2a1 |
A |
T |
13: 27,808,571 (GRCm38) |
N226I |
probably damaging |
Het |
| Pus7 |
A |
C |
5: 23,741,916 (GRCm38) |
M636R |
probably damaging |
Het |
| Samd9l |
G |
A |
6: 3,375,264 (GRCm38) |
Q666* |
probably null |
Het |
| Sema3d |
A |
G |
5: 12,584,887 (GRCm38) |
D640G |
probably benign |
Het |
| Slc6a15 |
A |
G |
10: 103,400,260 (GRCm38) |
I279V |
probably benign |
Het |
| Slk |
T |
C |
19: 47,620,534 (GRCm38) |
V642A |
possibly damaging |
Het |
| Spta1 |
T |
A |
1: 174,245,730 (GRCm38) |
M2305K |
probably damaging |
Het |
| Srrt |
T |
C |
5: 137,303,012 (GRCm38) |
|
probably benign |
Het |
| Stfa2l1 |
A |
T |
16: 36,156,858 (GRCm38) |
I8L |
probably benign |
Het |
| Tap1 |
T |
C |
17: 34,194,925 (GRCm38) |
L638P |
probably benign |
Het |
| Tbccd1 |
A |
T |
16: 22,822,245 (GRCm38) |
L461M |
probably benign |
Het |
| Tecta |
T |
C |
9: 42,378,049 (GRCm38) |
T407A |
probably benign |
Het |
| Tmbim7 |
T |
C |
5: 3,657,493 (GRCm38) |
|
probably null |
Het |
| Tnrc18 |
C |
A |
5: 142,815,114 (GRCm38) |
V30L |
probably benign |
Het |
| Tomm7 |
A |
G |
5: 23,844,027 (GRCm38) |
F16S |
probably damaging |
Het |
| Ugt2a2 |
A |
G |
5: 87,474,456 (GRCm38) |
S428P |
probably benign |
Het |
| Vmn1r189 |
T |
C |
13: 22,102,154 (GRCm38) |
E171G |
probably benign |
Het |
| Vmn1r61 |
T |
C |
7: 5,611,325 (GRCm38) |
|
probably benign |
Het |
| Vmn2r120 |
A |
T |
17: 57,525,038 (GRCm38) |
S250R |
probably benign |
Het |
| Vmn2r8 |
T |
C |
5: 108,803,106 (GRCm38) |
R158G |
probably benign |
Het |
| Vmn2r98 |
A |
T |
17: 19,066,440 (GRCm38) |
Y400F |
probably damaging |
Het |
| Vps13c |
C |
A |
9: 67,893,985 (GRCm38) |
Y582* |
probably null |
Het |
| Zfp518a |
T |
A |
19: 40,915,556 (GRCm38) |
F1310I |
probably benign |
Het |
| Zswim1 |
A |
G |
2: 164,825,400 (GRCm38) |
I191V |
probably benign |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,958,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,995,048 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,947,636 (GRCm38) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
131,002,795 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,935,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,958,089 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
131,002,754 (GRCm38) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
131,020,977 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,972,282 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,947,734 (GRCm38) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,970,144 (GRCm38) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,957,920 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,906,859 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,999,165 (GRCm38) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,986,826 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,980,134 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,906,856 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,995,085 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,970,227 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,957,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,999,161 (GRCm38) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
131,021,007 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,957,914 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,957,080 (GRCm38) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,935,624 (GRCm38) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,982,772 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,995,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,995,051 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,958,035 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,970,222 (GRCm38) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,935,588 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,957,996 (GRCm38) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,957,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,961,675 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
131,020,956 (GRCm38) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,994,207 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,964,930 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,994,228 (GRCm38) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,933,412 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,970,208 (GRCm38) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,960,468 (GRCm38) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,935,577 (GRCm38) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,935,577 (GRCm38) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,973,504 (GRCm38) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,982,042 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,999,130 (GRCm38) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,933,429 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
131,020,990 (GRCm38) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,995,047 (GRCm38) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,975,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,994,193 (GRCm38) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,970,124 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,999,130 (GRCm38) |
intron |
probably benign |
|
|
R5256:Atrn
|
UTSW |
2 |
130,946,019 (GRCm38) |
missense |
probably benign |
0.39 |
|
R5494:Atrn
|
UTSW |
2 |
131,023,075 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,970,016 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,906,544 (GRCm38) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,933,436 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
131,020,980 (GRCm38) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,946,091 (GRCm38) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,979,969 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
131,023,027 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,986,744 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,947,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,961,571 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,980,114 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,970,227 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,964,887 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,970,211 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,995,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,935,529 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
131,013,641 (GRCm38) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,975,988 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,960,549 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
131,023,000 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,935,584 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
131,004,574 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,906,878 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,906,601 (GRCm38) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,999,237 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,935,550 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,961,616 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,944,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,906,922 (GRCm38) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,958,139 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,973,399 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,946,193 (GRCm38) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,946,042 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTAACCTAAACATGGCACTGC -3'
(R):5'- TCCCTTCCTAAGAGAAAACCTGAG -3'
Sequencing Primer
(F):5'- GAGCTTTCCTACCTCAGA -3'
(R):5'- CTGAGCAACAGTAGAATTCAAATCG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation