Incidental Mutation 'R1800:Zfp318'
| ID |
203093 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp318
|
| Ensembl Gene |
ENSMUSG00000015597 |
| Gene Name |
zinc finger protein 318 |
| Synonyms |
2610034E08Rik, TZF, D530032D06Rik |
| MMRRC Submission |
039830-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1800 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
46694657-46731846 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 46722980 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1661
(V1661A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109109
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113481]
[ENSMUST00000138127]
[ENSMUST00000152472]
|
| AlphaFold |
Q99PP2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113481
AA Change: V1661A
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000109109
Gene: ENSMUSG00000015597
AA Change: V1661A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
916 |
995 |
2e-4 |
SMART |
|
low complexity region
|
1018 |
1055 |
N/A |
INTRINSIC |
|
ZnF_U1
|
1085 |
1119 |
5.99e-7 |
SMART |
|
ZnF_C2H2
|
1088 |
1112 |
4.5e1 |
SMART |
|
ZnF_U1
|
1155 |
1189 |
2.1e-11 |
SMART |
|
ZnF_C2H2
|
1158 |
1180 |
4.62e1 |
SMART |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1358 |
1371 |
N/A |
INTRINSIC |
|
low complexity region
|
1640 |
1651 |
N/A |
INTRINSIC |
|
Blast:HNHc
|
1660 |
1710 |
3e-17 |
BLAST |
|
low complexity region
|
2001 |
2013 |
N/A |
INTRINSIC |
|
low complexity region
|
2110 |
2121 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123733
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136017
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138127
|
| SMART Domains |
Protein: ENSMUSP00000116544
Gene: ENSMUSG00000015597
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
Blast:HOLI
|
854 |
1114 |
8e-19 |
BLAST |
|
SCOP:d1eq1a_
|
916 |
995 |
6e-5 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152472
|
| SMART Domains |
Protein: ENSMUSP00000116132
Gene: ENSMUSG00000015597
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
30 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.0%
- 20x: 91.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced male fertility and altered IgM and IgD levels. Null mutants displayed normal level of circulating B cells with decreased IgD and increased IgM levels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110002E22Rik |
A |
G |
3: 137,772,479 (GRCm39) |
K556R |
probably damaging |
Het |
| 4933406P04Rik |
A |
T |
10: 20,186,893 (GRCm39) |
|
probably benign |
Het |
| Acmsd |
C |
A |
1: 127,687,493 (GRCm39) |
Y258* |
probably null |
Het |
| Adgrf5 |
A |
T |
17: 43,761,973 (GRCm39) |
I1223F |
probably damaging |
Het |
| Afp |
C |
T |
5: 90,638,655 (GRCm39) |
P6S |
probably benign |
Het |
| Agap2 |
C |
A |
10: 126,927,540 (GRCm39) |
H1120Q |
probably damaging |
Het |
| Angpt1 |
A |
G |
15: 42,375,800 (GRCm39) |
V152A |
probably damaging |
Het |
| Ankrd1 |
A |
T |
19: 36,096,759 (GRCm39) |
F23I |
probably damaging |
Het |
| Armc12 |
T |
C |
17: 28,757,869 (GRCm39) |
S334P |
possibly damaging |
Het |
| Arnt2 |
C |
A |
7: 83,924,583 (GRCm39) |
D415Y |
probably damaging |
Het |
| Cacna1s |
G |
T |
1: 136,004,592 (GRCm39) |
V131L |
probably benign |
Het |
| Cacna2d2 |
T |
C |
9: 107,404,632 (GRCm39) |
V1141A |
possibly damaging |
Het |
| Cfap61 |
T |
C |
2: 145,884,542 (GRCm39) |
L580P |
probably damaging |
Het |
| Chga |
A |
T |
12: 102,522,164 (GRCm39) |
S23C |
probably damaging |
Het |
| Chrna5 |
A |
G |
9: 54,912,159 (GRCm39) |
T320A |
probably damaging |
Het |
| Col17a1 |
G |
T |
19: 47,639,301 (GRCm39) |
N1081K |
possibly damaging |
Het |
| Cox7b2 |
A |
T |
5: 71,600,406 (GRCm39) |
C51S |
possibly damaging |
Het |
| Cstdc3 |
T |
A |
16: 36,132,895 (GRCm39) |
D57E |
probably damaging |
Het |
| Cwc22 |
A |
T |
2: 77,759,797 (GRCm39) |
D83E |
possibly damaging |
Het |
| D130043K22Rik |
A |
C |
13: 25,067,877 (GRCm39) |
D871A |
probably damaging |
Het |
| Dab2 |
A |
T |
15: 6,464,948 (GRCm39) |
M361L |
probably benign |
Het |
| Dnah11 |
A |
C |
12: 117,880,523 (GRCm39) |
Y3866D |
probably damaging |
Het |
| Dnmbp |
A |
G |
19: 43,890,159 (GRCm39) |
I536T |
probably benign |
Het |
| Ehmt1 |
A |
T |
2: 24,774,302 (GRCm39) |
S43R |
probably damaging |
Het |
| Ercc5 |
T |
C |
1: 44,212,540 (GRCm39) |
L666P |
probably benign |
Het |
| F5 |
A |
G |
1: 164,010,403 (GRCm39) |
H378R |
probably damaging |
Het |
| Fat2 |
A |
T |
11: 55,174,718 (GRCm39) |
N1998K |
probably damaging |
Het |
| Fbxo28 |
T |
C |
1: 182,169,099 (GRCm39) |
D13G |
unknown |
Het |
| Fras1 |
T |
C |
5: 96,857,741 (GRCm39) |
S2012P |
probably benign |
Het |
| Gm5624 |
T |
A |
14: 44,799,302 (GRCm39) |
N41I |
probably damaging |
Het |
| Gm8104 |
A |
G |
14: 42,959,028 (GRCm39) |
I73V |
possibly damaging |
Het |
| Gpr141b |
T |
C |
13: 19,913,849 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr68 |
G |
A |
12: 100,845,167 (GRCm39) |
P126S |
probably damaging |
Het |
| Gucy1a2 |
A |
T |
9: 3,582,685 (GRCm39) |
T156S |
possibly damaging |
Het |
| Hacl1 |
T |
A |
14: 31,336,221 (GRCm39) |
Y429F |
probably damaging |
Het |
| Haus3 |
A |
C |
5: 34,320,916 (GRCm39) |
L510R |
probably damaging |
Het |
| Helq |
C |
T |
5: 100,921,990 (GRCm39) |
G738D |
probably benign |
Het |
| Hsd3b2 |
G |
C |
3: 98,619,553 (GRCm39) |
P131A |
probably damaging |
Het |
| Il22ra1 |
G |
T |
4: 135,475,471 (GRCm39) |
C247F |
probably benign |
Het |
| Ivl |
T |
C |
3: 92,479,891 (GRCm39) |
E58G |
unknown |
Het |
| Kcnk9 |
G |
T |
15: 72,417,948 (GRCm39) |
Q61K |
probably benign |
Het |
| Kremen1 |
CGGG |
CGGGGGG |
11: 5,151,791 (GRCm39) |
|
probably benign |
Het |
| Loxhd1 |
G |
T |
18: 77,490,198 (GRCm39) |
A1314S |
probably damaging |
Het |
| Lratd1 |
T |
C |
12: 14,200,226 (GRCm39) |
Y167C |
probably damaging |
Het |
| Lrba |
A |
G |
3: 86,259,175 (GRCm39) |
I1397V |
probably benign |
Het |
| Lrig3 |
T |
A |
10: 125,832,920 (GRCm39) |
|
probably null |
Het |
| Lrrc36 |
A |
G |
8: 106,176,397 (GRCm39) |
D378G |
probably damaging |
Het |
| Lrrc49 |
G |
A |
9: 60,505,474 (GRCm39) |
T527I |
probably damaging |
Het |
| Map4k4 |
C |
A |
1: 40,062,620 (GRCm39) |
T1195K |
probably damaging |
Het |
| Mrps33 |
G |
A |
6: 39,779,429 (GRCm39) |
R89C |
probably damaging |
Het |
| Mtor |
T |
C |
4: 148,547,349 (GRCm39) |
V444A |
probably benign |
Het |
| Myh2 |
A |
G |
11: 67,079,764 (GRCm39) |
E1046G |
probably damaging |
Het |
| Myo15b |
G |
T |
11: 115,771,335 (GRCm39) |
|
probably null |
Het |
| Myo5c |
T |
C |
9: 75,153,446 (GRCm39) |
Y111H |
probably damaging |
Het |
| Ncoa4-ps |
A |
T |
12: 119,225,506 (GRCm39) |
|
noncoding transcript |
Het |
| Ndufv2 |
G |
C |
17: 66,390,481 (GRCm39) |
T163R |
probably damaging |
Het |
| Nf1 |
A |
G |
11: 79,444,794 (GRCm39) |
N373S |
possibly damaging |
Het |
| Nwd2 |
A |
G |
5: 63,962,917 (GRCm39) |
M834V |
probably benign |
Het |
| Ogfod2 |
T |
C |
5: 124,253,019 (GRCm39) |
V343A |
probably damaging |
Het |
| Or11g2 |
C |
T |
14: 50,856,143 (GRCm39) |
L155F |
probably benign |
Het |
| Or11j4 |
C |
A |
14: 50,630,786 (GRCm39) |
S191* |
probably null |
Het |
| Or3a1b |
A |
T |
11: 74,012,234 (GRCm39) |
T40S |
probably benign |
Het |
| Or4c115 |
T |
A |
2: 88,928,050 (GRCm39) |
T74S |
probably benign |
Het |
| Or51ag1 |
T |
C |
7: 103,155,248 (GRCm39) |
I302V |
possibly damaging |
Het |
| Or52ab2 |
T |
A |
7: 102,969,621 (GRCm39) |
M1K |
probably null |
Het |
| Or8g34 |
A |
T |
9: 39,373,410 (GRCm39) |
I228F |
probably damaging |
Het |
| Parp1 |
T |
A |
1: 180,428,091 (GRCm39) |
|
probably null |
Het |
| Ppp3ca |
A |
T |
3: 136,640,792 (GRCm39) |
I448F |
probably damaging |
Het |
| Prss44 |
T |
C |
9: 110,646,272 (GRCm39) |
V333A |
probably damaging |
Het |
| Pxk |
C |
T |
14: 8,151,507 (GRCm38) |
R441* |
probably null |
Het |
| Rars1 |
A |
C |
11: 35,716,822 (GRCm39) |
D231E |
probably benign |
Het |
| Rfc1 |
T |
C |
5: 65,421,722 (GRCm39) |
Y1059C |
probably damaging |
Het |
| Rilpl1 |
T |
A |
5: 124,652,719 (GRCm39) |
I2F |
probably damaging |
Het |
| Sarm1 |
G |
T |
11: 78,381,820 (GRCm39) |
A221E |
possibly damaging |
Het |
| Serpina3f |
A |
G |
12: 104,183,665 (GRCm39) |
T176A |
probably damaging |
Het |
| Slc22a20 |
T |
C |
19: 6,035,695 (GRCm39) |
E131G |
probably benign |
Het |
| Slc26a11 |
T |
C |
11: 119,263,979 (GRCm39) |
V343A |
probably damaging |
Het |
| Slc2a4 |
A |
G |
11: 69,837,133 (GRCm39) |
I9T |
probably benign |
Het |
| Slc39a6 |
G |
T |
18: 24,718,259 (GRCm39) |
D599E |
probably damaging |
Het |
| Slc5a6 |
G |
T |
5: 31,198,020 (GRCm39) |
S285* |
probably null |
Het |
| Spata9 |
A |
G |
13: 76,125,760 (GRCm39) |
H81R |
probably benign |
Het |
| St7l |
A |
G |
3: 104,826,812 (GRCm39) |
E436G |
probably damaging |
Het |
| Tecrl |
A |
G |
5: 83,427,077 (GRCm39) |
I357T |
probably damaging |
Het |
| Thop1 |
C |
T |
10: 80,909,043 (GRCm39) |
R25C |
probably damaging |
Het |
| Tmprss12 |
A |
G |
15: 100,190,428 (GRCm39) |
E266G |
probably benign |
Het |
| Tpgs1 |
T |
A |
10: 79,511,344 (GRCm39) |
V162D |
possibly damaging |
Het |
| Trpa1 |
C |
T |
1: 14,944,648 (GRCm39) |
R1032Q |
probably benign |
Het |
| Tspan12 |
A |
G |
6: 21,795,699 (GRCm39) |
Y164H |
probably damaging |
Het |
| Ubr4 |
T |
C |
4: 139,135,274 (GRCm39) |
Y869H |
probably damaging |
Het |
| Vmn1r21 |
A |
G |
6: 57,820,799 (GRCm39) |
I215T |
probably benign |
Het |
| Zan |
A |
T |
5: 137,384,713 (GRCm39) |
S5104T |
unknown |
Het |
| Zfp365 |
C |
T |
10: 67,724,772 (GRCm39) |
R372K |
probably damaging |
Het |
|
| Other mutations in Zfp318 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00705:Zfp318
|
APN |
17 |
46,723,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00978:Zfp318
|
APN |
17 |
46,724,652 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01016:Zfp318
|
APN |
17 |
46,711,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01310:Zfp318
|
APN |
17 |
46,724,153 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01453:Zfp318
|
APN |
17 |
46,719,942 (GRCm39) |
splice site |
probably null |
|
|
IGL01887:Zfp318
|
APN |
17 |
46,710,094 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02025:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02026:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02070:Zfp318
|
APN |
17 |
46,707,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02182:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02187:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02188:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02189:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02190:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02191:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02192:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02203:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02224:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02230:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02232:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02233:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02234:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Zfp318
|
APN |
17 |
46,720,043 (GRCm39) |
nonsense |
probably null |
|
|
IGL02792:Zfp318
|
APN |
17 |
46,720,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02826:Zfp318
|
APN |
17 |
46,709,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Wonton
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
I0000:Zfp318
|
UTSW |
17 |
46,710,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0206:Zfp318
|
UTSW |
17 |
46,709,945 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0281:Zfp318
|
UTSW |
17 |
46,723,540 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0350:Zfp318
|
UTSW |
17 |
46,724,124 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0383:Zfp318
|
UTSW |
17 |
46,724,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0453:Zfp318
|
UTSW |
17 |
46,707,634 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1014:Zfp318
|
UTSW |
17 |
46,723,462 (GRCm39) |
nonsense |
probably null |
|
|
R1166:Zfp318
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1327:Zfp318
|
UTSW |
17 |
46,724,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1330:Zfp318
|
UTSW |
17 |
46,724,684 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1737:Zfp318
|
UTSW |
17 |
46,710,403 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1846:Zfp318
|
UTSW |
17 |
46,724,592 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1848:Zfp318
|
UTSW |
17 |
46,716,981 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1861:Zfp318
|
UTSW |
17 |
46,722,366 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1913:Zfp318
|
UTSW |
17 |
46,723,450 (GRCm39) |
unclassified |
probably benign |
|
|
R1913:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R2059:Zfp318
|
UTSW |
17 |
46,707,950 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2085:Zfp318
|
UTSW |
17 |
46,720,590 (GRCm39) |
splice site |
probably null |
|
|
R2122:Zfp318
|
UTSW |
17 |
46,724,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2339:Zfp318
|
UTSW |
17 |
46,710,389 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4526:Zfp318
|
UTSW |
17 |
46,723,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4564:Zfp318
|
UTSW |
17 |
46,723,741 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4689:Zfp318
|
UTSW |
17 |
46,710,560 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4795:Zfp318
|
UTSW |
17 |
46,722,988 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5256:Zfp318
|
UTSW |
17 |
46,722,995 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5317:Zfp318
|
UTSW |
17 |
46,723,463 (GRCm39) |
unclassified |
probably benign |
|
|
R5323:Zfp318
|
UTSW |
17 |
46,697,662 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5436:Zfp318
|
UTSW |
17 |
46,723,975 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5485:Zfp318
|
UTSW |
17 |
46,723,180 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5627:Zfp318
|
UTSW |
17 |
46,724,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5643:Zfp318
|
UTSW |
17 |
46,720,170 (GRCm39) |
intron |
probably benign |
|
|
R5782:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5783:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5820:Zfp318
|
UTSW |
17 |
46,723,699 (GRCm39) |
missense |
probably benign |
|
|
R5895:Zfp318
|
UTSW |
17 |
46,709,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R6385:Zfp318
|
UTSW |
17 |
46,721,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Zfp318
|
UTSW |
17 |
46,710,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Zfp318
|
UTSW |
17 |
46,710,431 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6666:Zfp318
|
UTSW |
17 |
46,720,140 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6812:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,464 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,459 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,460 (GRCm39) |
unclassified |
probably benign |
|
|
R6854:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6980:Zfp318
|
UTSW |
17 |
46,708,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6999:Zfp318
|
UTSW |
17 |
46,710,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,716,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,708,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7175:Zfp318
|
UTSW |
17 |
46,697,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7233:Zfp318
|
UTSW |
17 |
46,716,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7339:Zfp318
|
UTSW |
17 |
46,722,173 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7426:Zfp318
|
UTSW |
17 |
46,710,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7600:Zfp318
|
UTSW |
17 |
46,695,210 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7608:Zfp318
|
UTSW |
17 |
46,710,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7779:Zfp318
|
UTSW |
17 |
46,710,820 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8057:Zfp318
|
UTSW |
17 |
46,710,692 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8273:Zfp318
|
UTSW |
17 |
46,723,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8274:Zfp318
|
UTSW |
17 |
46,723,915 (GRCm39) |
missense |
probably benign |
|
|
R8695:Zfp318
|
UTSW |
17 |
46,723,576 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8822:Zfp318
|
UTSW |
17 |
46,723,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8851:Zfp318
|
UTSW |
17 |
46,710,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Zfp318
|
UTSW |
17 |
46,722,699 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8953:Zfp318
|
UTSW |
17 |
46,731,356 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9031:Zfp318
|
UTSW |
17 |
46,723,433 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9327:Zfp318
|
UTSW |
17 |
46,721,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9329:Zfp318
|
UTSW |
17 |
46,722,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Zfp318
|
UTSW |
17 |
46,721,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9633:Zfp318
|
UTSW |
17 |
46,710,421 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9662:Zfp318
|
UTSW |
17 |
46,724,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9728:Zfp318
|
UTSW |
17 |
46,707,713 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9755:Zfp318
|
UTSW |
17 |
46,722,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Zfp318
|
UTSW |
17 |
46,721,564 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
X0054:Zfp318
|
UTSW |
17 |
46,723,535 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
X0065:Zfp318
|
UTSW |
17 |
46,721,915 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Zfp318
|
UTSW |
17 |
46,716,904 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTCGTGCTTAGCCACAGCC -3'
(R):5'- CAAAGTGTCTGTCTTTGGGGAAAC -3'
Sequencing Primer
(F):5'- GCCAATGCTAAGGACCTGTATG -3'
(R):5'- CTTTGGGGAAACTATTTCATAAGGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation