Mutagenetix > Incidental Mutation

Incidental Mutation 'R1801:Tenm3'

203141

Institutional Source

Beutler Lab

Gene Symbol

Tenm3

Ensembl Gene

ENSMUSG00000031561

Gene Name

teneurin transmembrane protein 3

Synonyms

Odz3, Ten-m3, 2610100B16Rik

MMRRC Submission

039831-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.472) question?

Stock #

R1801 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

48680717-49296986 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to A at 48729291 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Leucine at position 1572 (V1572L)

Ref Sequence

ENSEMBL: ENSMUSP00000033965 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000033965] [ENSMUST00000190840]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000033965
AA Change: V1572L

PolyPhen 2 Score 0.394 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000033965
Gene: ENSMUSG00000031561
AA Change: V1572L

Domain	Start	End	E-Value	Type
Pfam:Ten_N	11	177	6.9e-91	PFAM
Pfam:Ten_N	171	308	1e-72	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2631	2708	1.5e-34	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000145344

Predicted Effect

probably benign
Transcript: ENSMUST00000190840
AA Change: V1556L

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000140141
Gene: ENSMUSG00000031561
AA Change: V1556L

Domain	Start	End	E-Value	Type
Pfam:Ten_N	10	182	7.6e-77	PFAM
Pfam:Ten_N	168	308	6.6e-50	PFAM
transmembrane domain	309	331	N/A	INTRINSIC
EGF	517	545	2.32e-1	SMART
EGF_like	548	576	4.11e1	SMART
EGF	581	610	1.69e1	SMART
EGF	613	642	1.35e-2	SMART
EGF	647	677	6.11e-1	SMART
EGF	680	708	7.95e0	SMART
EGF	711	739	1.28e1	SMART
EGF	751	783	1.64e-1	SMART
PDB:1RWL\|A	1276	1511	9e-6	PDB
low complexity region	2593	2602	N/A	INTRINSIC
Pfam:Tox-GHH	2630	2708	3.2e-35	PFAM

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.1%
20x: 91.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large transmembrane protein that may be involved in the regulation of neuronal development. Mutation in this gene causes microphthalmia. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null mutation display abnormal ipsilateral retinal ganglion cell projections and impaired performance in visually mediated behavioral tasks. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 73 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610008E11Rik	T	C	10: 78,903,230 (GRCm39)	E362G	probably damaging	Het
Abcc5	T	C	16: 20,157,637 (GRCm39)	M1307V	probably benign	Het
Adam34l	A	T	8: 44,078,954 (GRCm39)	C423*	probably null	Het
Adamts9	A	G	6: 92,840,357 (GRCm39)	V1142A	probably benign	Het
Ano10	T	C	9: 122,082,096 (GRCm39)	N525S	probably damaging	Het
Bpifa2	T	C	2: 153,853,424 (GRCm39)		probably null	Het
C7	C	T	15: 5,041,503 (GRCm39)	V468I	possibly damaging	Het
Carf	A	T	1: 60,180,664 (GRCm39)	H362L	possibly damaging	Het
Ccdc171	A	C	4: 83,465,132 (GRCm39)	I37L	probably benign	Het
Ccdc182	T	C	11: 88,185,016 (GRCm39)	L32P	possibly damaging	Het
Celsr3	A	T	9: 108,711,825 (GRCm39)	D1678V	possibly damaging	Het
Col7a1	A	T	9: 108,790,065 (GRCm39)	Y920F	unknown	Het
Cpsf3	T	C	12: 21,363,791 (GRCm39)	V627A	probably benign	Het
D7Ertd443e	A	G	7: 133,871,941 (GRCm39)	M640T	probably damaging	Het
Ddi2	T	C	4: 141,411,283 (GRCm39)	D543G	probably damaging	Het
Dnah9	T	C	11: 65,846,123 (GRCm39)	N2972D	probably damaging	Het
Dnajc18	T	C	18: 35,813,857 (GRCm39)	D304G	probably damaging	Het
Epg5	T	C	18: 78,026,705 (GRCm39)	V1232A	possibly damaging	Het
Ezr	T	C	17: 7,009,771 (GRCm39)	T358A	possibly damaging	Het
Filip1	A	G	9: 79,723,128 (GRCm39)	S1164P	probably damaging	Het
Gmip	T	C	8: 70,267,127 (GRCm39)	V341A	probably benign	Het
Gnb3	A	C	6: 124,812,599 (GRCm39)	F286V	probably benign	Het
Gpatch2	T	A	1: 186,958,028 (GRCm39)	S128T	probably benign	Het
Gpr87	T	C	3: 59,086,813 (GRCm39)	R231G	possibly damaging	Het
Hip1r	G	A	5: 124,136,871 (GRCm39)	R613Q	probably benign	Het
Hsd3b7	T	C	7: 127,402,206 (GRCm39)	Y284H	possibly damaging	Het
Il1rap	A	T	16: 26,517,625 (GRCm39)	D275V	probably damaging	Het
Il4	G	T	11: 53,509,365 (GRCm39)	H23Q	possibly damaging	Het
Kit	A	G	5: 75,809,053 (GRCm39)	Y749C	probably damaging	Het
Klb	A	G	5: 65,506,578 (GRCm39)	K275R	probably null	Het
Klhl12	G	T	1: 134,416,808 (GRCm39)	R510L	probably damaging	Het
Lrrc8b	A	G	5: 105,628,689 (GRCm39)	Y345C	probably damaging	Het
Med15	T	C	16: 17,498,599 (GRCm39)	T98A	possibly damaging	Het
Mmp1a	T	A	9: 7,475,391 (GRCm39)	Y387N	probably damaging	Het
Myrf	C	A	19: 10,191,555 (GRCm39)	V928L	probably benign	Het
Nr1d1	T	C	11: 98,662,325 (GRCm39)	K134E	probably damaging	Het
Nrxn3	A	T	12: 90,250,356 (GRCm39)	D305V	probably damaging	Het
Obscn	A	C	11: 58,889,147 (GRCm39)	S7542A	unknown	Het
Or4a27	T	A	2: 88,559,608 (GRCm39)	I112F	probably damaging	Het
Pak4	G	A	7: 28,264,615 (GRCm39)	R96C	probably damaging	Het
Pde6b	A	T	5: 108,575,713 (GRCm39)	D691V	possibly damaging	Het
Pdss2	A	G	10: 43,221,601 (GRCm39)	E171G	probably benign	Het
Pdzd2	C	T	15: 12,387,740 (GRCm39)	V873I	possibly damaging	Het
Plb1	A	T	5: 32,450,587 (GRCm39)	D376V	probably damaging	Het
Plekhg1	T	C	10: 3,913,904 (GRCm39)	Y1209H	probably damaging	Het
Prickle2	A	G	6: 92,393,885 (GRCm39)	C263R	probably damaging	Het
Psma2	A	T	13: 14,798,190 (GRCm39)	Y104F	probably benign	Het
Ptger4	T	A	15: 5,272,281 (GRCm39)	M113L	possibly damaging	Het
Rgs10	T	G	7: 128,006,201 (GRCm39)	D17A	possibly damaging	Het
Rpap3	A	G	15: 97,592,090 (GRCm39)	S189P	possibly damaging	Het
Rsbn1	T	C	3: 103,822,188 (GRCm39)	L102P	probably damaging	Het
Ryr2	T	C	13: 11,610,167 (GRCm39)	S655G	probably benign	Het
Samd4b	A	T	7: 28,106,756 (GRCm39)		probably null	Het
Sema4a	C	T	3: 88,344,056 (GRCm39)	D732N	probably benign	Het
Sh3bp5l	A	G	11: 58,237,177 (GRCm39)	D378G	probably benign	Het
Sh3gl3	C	T	7: 81,933,327 (GRCm39)	T230I	possibly damaging	Het
Slc28a2b	C	T	2: 122,352,133 (GRCm39)	R324C	possibly damaging	Het
Slc5a1	A	T	5: 33,304,297 (GRCm39)	Q299L	probably damaging	Het
Ssc5d	C	A	7: 4,939,606 (GRCm39)	H681N	probably benign	Het
Sugp2	T	C	8: 70,689,360 (GRCm39)	S10P	possibly damaging	Het
Supt5	A	G	7: 28,016,639 (GRCm39)		probably null	Het
Syna	A	G	5: 134,588,943 (GRCm39)	V2A	probably benign	Het
Tcp1	T	A	17: 13,141,089 (GRCm39)	Y299*	probably null	Het
Tent4b	T	G	8: 88,977,416 (GRCm39)	V406G	probably benign	Het
Trp53rka	A	G	2: 165,333,533 (GRCm39)	S119P	probably damaging	Het
Ubr4	T	A	4: 139,179,874 (GRCm39)		probably null	Het
Uchl4	T	A	9: 64,142,757 (GRCm39)	D79E	probably benign	Het
Vmn2r17	C	A	5: 109,576,344 (GRCm39)	T405K	probably damaging	Het
Xpnpep1	A	G	19: 52,998,564 (GRCm39)	L228P	probably damaging	Het
Xrcc4	T	G	13: 90,140,698 (GRCm39)	E170D	probably damaging	Het
Zfp945	T	C	17: 23,070,736 (GRCm39)	T388A	probably damaging	Het
Zfp947	G	A	17: 22,365,443 (GRCm39)	A77V	probably benign	Het
Zkscan5	G	A	5: 145,157,015 (GRCm39)	G433R	probably damaging	Het

Other mutations in Tenm3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Tenm3	APN	8	48,870,095 (GRCm39)	missense	probably damaging	1.00
IGL00538:Tenm3	APN	8	48,689,060 (GRCm39)	missense	probably damaging	1.00
IGL00719:Tenm3	APN	8	48,732,077 (GRCm39)	missense	probably benign	0.39
IGL00720:Tenm3	APN	8	48,729,456 (GRCm39)	missense	probably damaging	0.98
IGL00870:Tenm3	APN	8	48,870,167 (GRCm39)	missense	probably benign	0.00
IGL00976:Tenm3	APN	8	48,709,876 (GRCm39)	missense	probably benign	0.14
IGL01469:Tenm3	APN	8	48,689,458 (GRCm39)	missense	probably damaging	1.00
IGL01508:Tenm3	APN	8	48,729,680 (GRCm39)	missense	probably benign	0.09
IGL01590:Tenm3	APN	8	48,681,837 (GRCm39)	missense	probably damaging	1.00
IGL01610:Tenm3	APN	8	48,707,512 (GRCm39)	missense	probably damaging	1.00
IGL01874:Tenm3	APN	8	48,689,793 (GRCm39)	nonsense	probably null
IGL01892:Tenm3	APN	8	48,729,431 (GRCm39)	missense	probably benign	0.09
IGL02098:Tenm3	APN	8	48,729,611 (GRCm39)	missense	possibly damaging	0.94
IGL02382:Tenm3	APN	8	48,688,511 (GRCm39)	missense	probably damaging	1.00
IGL02397:Tenm3	APN	8	48,689,729 (GRCm39)	missense	possibly damaging	0.94
IGL02475:Tenm3	APN	8	48,732,233 (GRCm39)	splice site	probably benign
IGL02502:Tenm3	APN	8	48,741,051 (GRCm39)	missense	probably damaging	1.00
IGL02508:Tenm3	APN	8	48,752,674 (GRCm39)	missense	probably benign	0.30
IGL02543:Tenm3	APN	8	48,751,991 (GRCm39)	missense	probably damaging	1.00
IGL02723:Tenm3	APN	8	48,729,938 (GRCm39)	missense	probably benign	0.02
IGL03037:Tenm3	APN	8	48,751,913 (GRCm39)	missense	possibly damaging	0.90
IGL03160:Tenm3	APN	8	49,099,453 (GRCm39)	missense	probably benign	0.05
IGL03268:Tenm3	APN	8	48,688,558 (GRCm39)	missense	probably damaging	1.00
IGL02988:Tenm3	UTSW	8	48,688,381 (GRCm39)	missense	probably damaging	0.99
PIT4431001:Tenm3	UTSW	8	48,688,642 (GRCm39)	missense	probably damaging	1.00
PIT4504001:Tenm3	UTSW	8	48,746,692 (GRCm39)	missense	probably damaging	1.00
R0079:Tenm3	UTSW	8	48,796,380 (GRCm39)	missense	possibly damaging	0.90
R0121:Tenm3	UTSW	8	48,795,694 (GRCm39)	missense	probably damaging	0.99
R0123:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0134:Tenm3	UTSW	8	49,127,507 (GRCm39)	missense	probably damaging	1.00
R0147:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0148:Tenm3	UTSW	8	48,689,755 (GRCm39)	missense	probably damaging	1.00
R0309:Tenm3	UTSW	8	48,794,069 (GRCm39)	missense	probably damaging	1.00
R0322:Tenm3	UTSW	8	48,689,947 (GRCm39)	splice site	probably benign
R0335:Tenm3	UTSW	8	48,685,140 (GRCm39)	missense	probably damaging	1.00
R0355:Tenm3	UTSW	8	48,682,010 (GRCm39)	missense	probably damaging	1.00
R0411:Tenm3	UTSW	8	48,740,826 (GRCm39)	missense	possibly damaging	0.61
R0505:Tenm3	UTSW	8	48,794,195 (GRCm39)	splice site	probably benign
R0573:Tenm3	UTSW	8	49,127,434 (GRCm39)	splice site	probably benign
R0599:Tenm3	UTSW	8	48,730,745 (GRCm39)	missense	probably damaging	1.00
R0616:Tenm3	UTSW	8	48,729,191 (GRCm39)	missense	possibly damaging	0.76
R0637:Tenm3	UTSW	8	48,689,560 (GRCm39)	missense	probably damaging	1.00
R0726:Tenm3	UTSW	8	48,689,629 (GRCm39)	missense	probably damaging	1.00
R0840:Tenm3	UTSW	8	48,788,777 (GRCm39)	missense	probably damaging	0.99
R0981:Tenm3	UTSW	8	48,752,000 (GRCm39)	missense	probably damaging	1.00
R1006:Tenm3	UTSW	8	48,681,577 (GRCm39)	missense	probably damaging	1.00
R1199:Tenm3	UTSW	8	48,688,617 (GRCm39)	missense	probably damaging	0.99
R1223:Tenm3	UTSW	8	48,693,431 (GRCm39)	missense	possibly damaging	0.72
R1240:Tenm3	UTSW	8	48,740,928 (GRCm39)	missense	possibly damaging	0.74
R1394:Tenm3	UTSW	8	48,729,435 (GRCm39)	missense	probably benign
R1455:Tenm3	UTSW	8	48,732,083 (GRCm39)	missense	possibly damaging	0.87
R1459:Tenm3	UTSW	8	48,689,006 (GRCm39)	missense	probably damaging	1.00
R1473:Tenm3	UTSW	8	48,763,660 (GRCm39)	missense	probably damaging	1.00
R1501:Tenm3	UTSW	8	48,796,351 (GRCm39)	missense	probably damaging	0.99
R1507:Tenm3	UTSW	8	48,740,857 (GRCm39)	missense	probably benign	0.01
R1522:Tenm3	UTSW	8	48,848,611 (GRCm39)	missense	probably damaging	1.00
R1524:Tenm3	UTSW	8	48,682,016 (GRCm39)	missense	possibly damaging	0.92
R1553:Tenm3	UTSW	8	48,689,456 (GRCm39)	missense	probably damaging	1.00
R1572:Tenm3	UTSW	8	48,682,028 (GRCm39)	missense	possibly damaging	0.94
R1583:Tenm3	UTSW	8	48,732,109 (GRCm39)	missense	probably benign	0.09
R1676:Tenm3	UTSW	8	48,870,154 (GRCm39)	missense	possibly damaging	0.83
R1732:Tenm3	UTSW	8	48,763,669 (GRCm39)	missense	probably damaging	1.00
R1768:Tenm3	UTSW	8	48,685,139 (GRCm39)	missense	probably damaging	1.00
R1777:Tenm3	UTSW	8	48,870,214 (GRCm39)	missense	probably benign	0.05
R1793:Tenm3	UTSW	8	49,127,579 (GRCm39)	missense	probably damaging	0.98
R1863:Tenm3	UTSW	8	48,729,381 (GRCm39)	missense	probably benign	0.20
R1898:Tenm3	UTSW	8	48,763,796 (GRCm39)	missense	probably damaging	1.00
R1971:Tenm3	UTSW	8	48,689,348 (GRCm39)	missense	probably damaging	1.00
R1972:Tenm3	UTSW	8	48,681,626 (GRCm39)	missense	probably damaging	1.00
R1996:Tenm3	UTSW	8	48,681,703 (GRCm39)	missense	probably damaging	1.00
R2061:Tenm3	UTSW	8	48,795,291 (GRCm39)	critical splice donor site	probably null
R2109:Tenm3	UTSW	8	48,796,384 (GRCm39)	missense	possibly damaging	0.94
R2124:Tenm3	UTSW	8	48,870,041 (GRCm39)	critical splice donor site	probably null
R2190:Tenm3	UTSW	8	48,848,579 (GRCm39)	missense	probably damaging	1.00
R2204:Tenm3	UTSW	8	49,127,585 (GRCm39)	missense	probably benign	0.17
R2233:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2234:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2235:Tenm3	UTSW	8	48,729,204 (GRCm39)	missense	probably benign	0.04
R2237:Tenm3	UTSW	8	48,795,372 (GRCm39)	missense	probably damaging	1.00
R2418:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2419:Tenm3	UTSW	8	48,729,693 (GRCm39)	missense	possibly damaging	0.87
R2435:Tenm3	UTSW	8	48,740,988 (GRCm39)	missense	probably damaging	1.00
R2483:Tenm3	UTSW	8	48,693,305 (GRCm39)	missense	probably damaging	0.99
R3406:Tenm3	UTSW	8	48,681,590 (GRCm39)	missense	probably damaging	1.00
R3724:Tenm3	UTSW	8	48,730,781 (GRCm39)	missense	probably damaging	0.97
R4009:Tenm3	UTSW	8	48,802,258 (GRCm39)	missense	probably damaging	1.00
R4210:Tenm3	UTSW	8	48,802,439 (GRCm39)	missense	probably damaging	1.00
R4293:Tenm3	UTSW	8	48,848,693 (GRCm39)	missense	probably damaging	1.00
R4656:Tenm3	UTSW	8	48,746,761 (GRCm39)	missense	probably damaging	1.00
R4663:Tenm3	UTSW	8	48,689,005 (GRCm39)	missense	probably damaging	1.00
R4835:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R4851:Tenm3	UTSW	8	48,763,656 (GRCm39)	critical splice donor site	probably null
R4867:Tenm3	UTSW	8	48,688,856 (GRCm39)	missense	probably damaging	1.00
R4892:Tenm3	UTSW	8	48,729,896 (GRCm39)	missense	probably damaging	0.99
R4895:Tenm3	UTSW	8	48,754,006 (GRCm39)	missense	probably damaging	1.00
R4962:Tenm3	UTSW	8	48,731,996 (GRCm39)	nonsense	probably null
R4995:Tenm3	UTSW	8	48,682,172 (GRCm39)	missense	possibly damaging	0.87
R4996:Tenm3	UTSW	8	48,688,861 (GRCm39)	missense	probably damaging	0.97
R5091:Tenm3	UTSW	8	48,795,343 (GRCm39)	missense	probably benign	0.14
R5228:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5253:Tenm3	UTSW	8	48,682,233 (GRCm39)	missense	possibly damaging	0.92
R5260:Tenm3	UTSW	8	48,689,890 (GRCm39)	missense	probably damaging	1.00
R5363:Tenm3	UTSW	8	48,740,866 (GRCm39)	missense	possibly damaging	0.55
R5414:Tenm3	UTSW	8	48,689,390 (GRCm39)	missense	probably damaging	1.00
R5427:Tenm3	UTSW	8	48,689,599 (GRCm39)	missense	probably damaging	1.00
R5431:Tenm3	UTSW	8	48,820,412 (GRCm39)	nonsense	probably null
R5566:Tenm3	UTSW	8	48,732,041 (GRCm39)	missense	probably damaging	1.00
R5579:Tenm3	UTSW	8	48,689,799 (GRCm39)	missense	probably damaging	1.00
R5656:Tenm3	UTSW	8	48,681,797 (GRCm39)	missense	probably damaging	1.00
R5931:Tenm3	UTSW	8	49,099,533 (GRCm39)	missense	probably benign	0.00
R5959:Tenm3	UTSW	8	49,099,482 (GRCm39)	nonsense	probably null
R5965:Tenm3	UTSW	8	48,681,543 (GRCm39)	nonsense	probably null
R6062:Tenm3	UTSW	8	48,796,441 (GRCm39)	missense	possibly damaging	0.46
R6151:Tenm3	UTSW	8	48,848,608 (GRCm39)	missense	probably damaging	1.00
R6157:Tenm3	UTSW	8	48,751,843 (GRCm39)	missense	probably damaging	0.96
R6167:Tenm3	UTSW	8	48,707,657 (GRCm39)	missense	possibly damaging	0.46
R6217:Tenm3	UTSW	8	48,746,700 (GRCm39)	missense	probably damaging	0.99
R6233:Tenm3	UTSW	8	48,870,094 (GRCm39)	missense	probably damaging	1.00
R6270:Tenm3	UTSW	8	48,820,429 (GRCm39)	missense	probably damaging	0.98
R6329:Tenm3	UTSW	8	48,729,884 (GRCm39)	missense	probably damaging	0.99
R6466:Tenm3	UTSW	8	48,689,098 (GRCm39)	missense	probably damaging	0.97
R6515:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6516:Tenm3	UTSW	8	48,870,257 (GRCm39)	missense	probably benign
R6747:Tenm3	UTSW	8	48,796,278 (GRCm39)	missense	probably damaging	1.00
R6782:Tenm3	UTSW	8	49,099,291 (GRCm39)	critical splice donor site	probably null
R6788:Tenm3	UTSW	8	49,127,528 (GRCm39)	missense	probably damaging	1.00
R6823:Tenm3	UTSW	8	48,709,872 (GRCm39)	missense	probably damaging	0.99
R6846:Tenm3	UTSW	8	48,729,773 (GRCm39)	missense	probably benign	0.39
R6913:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R6941:Tenm3	UTSW	8	49,127,451 (GRCm39)	missense	probably damaging	0.99
R6950:Tenm3	UTSW	8	48,693,514 (GRCm39)	nonsense	probably null
R6968:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6970:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R6993:Tenm3	UTSW	8	48,689,474 (GRCm39)	missense	probably damaging	1.00
R7003:Tenm3	UTSW	8	48,693,479 (GRCm39)	missense	probably damaging	1.00
R7125:Tenm3	UTSW	8	49,127,588 (GRCm39)	missense	probably benign	0.00
R7140:Tenm3	UTSW	8	48,745,271 (GRCm39)	missense	probably damaging	1.00
R7222:Tenm3	UTSW	8	48,754,004 (GRCm39)	missense	probably damaging	1.00
R7232:Tenm3	UTSW	8	48,688,970 (GRCm39)	missense	probably damaging	1.00
R7336:Tenm3	UTSW	8	48,689,212 (GRCm39)	missense	possibly damaging	0.93
R7417:Tenm3	UTSW	8	48,689,218 (GRCm39)	missense	probably damaging	1.00
R7526:Tenm3	UTSW	8	48,740,847 (GRCm39)	missense	probably damaging	0.96
R7527:Tenm3	UTSW	8	48,729,635 (GRCm39)	missense	possibly damaging	0.60
R7616:Tenm3	UTSW	8	48,794,084 (GRCm39)	missense	possibly damaging	0.56
R7662:Tenm3	UTSW	8	48,788,762 (GRCm39)	missense	probably benign	0.27
R7734:Tenm3	UTSW	8	49,099,368 (GRCm39)	missense	probably damaging	1.00
R7802:Tenm3	UTSW	8	48,689,500 (GRCm39)	missense	probably damaging	1.00
R7812:Tenm3	UTSW	8	48,729,335 (GRCm39)	missense	probably benign	0.01
R7843:Tenm3	UTSW	8	48,682,146 (GRCm39)	nonsense	probably null
R7951:Tenm3	UTSW	8	48,763,738 (GRCm39)	missense	possibly damaging	0.86
R8293:Tenm3	UTSW	8	48,820,457 (GRCm39)	missense	possibly damaging	0.91
R8336:Tenm3	UTSW	8	48,746,808 (GRCm39)	missense	probably damaging	1.00
R8351:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8387:Tenm3	UTSW	8	48,740,883 (GRCm39)	missense	probably damaging	0.98
R8414:Tenm3	UTSW	8	48,746,544 (GRCm39)	missense	probably damaging	1.00
R8451:Tenm3	UTSW	8	48,740,907 (GRCm39)	missense	probably damaging	0.96
R8465:Tenm3	UTSW	8	48,682,216 (GRCm39)	missense	probably damaging	1.00
R8528:Tenm3	UTSW	8	48,795,668 (GRCm39)	missense	probably damaging	1.00
R8717:Tenm3	UTSW	8	48,752,680 (GRCm39)	missense	possibly damaging	0.77
R8734:Tenm3	UTSW	8	48,802,391 (GRCm39)	missense	probably benign	0.16
R8781:Tenm3	UTSW	8	48,795,484 (GRCm39)	frame shift	probably null
R8820:Tenm3	UTSW	8	48,763,759 (GRCm39)	missense	probably damaging	0.96
R8821:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8831:Tenm3	UTSW	8	48,729,417 (GRCm39)	missense
R8853:Tenm3	UTSW	8	48,795,382 (GRCm39)	missense	probably damaging	1.00
R8900:Tenm3	UTSW	8	48,689,437 (GRCm39)	missense	probably damaging	1.00
R8931:Tenm3	UTSW	8	48,688,637 (GRCm39)	missense	probably damaging	1.00
R8933:Tenm3	UTSW	8	48,732,095 (GRCm39)	missense	possibly damaging	0.53
R8989:Tenm3	UTSW	8	48,688,383 (GRCm39)	nonsense	probably null
R8998:Tenm3	UTSW	8	48,729,722 (GRCm39)	missense	probably damaging	1.00
R9008:Tenm3	UTSW	8	48,795,688 (GRCm39)	missense	probably damaging	0.98
R9017:Tenm3	UTSW	8	48,707,668 (GRCm39)	missense	probably damaging	0.99
R9101:Tenm3	UTSW	8	48,745,186 (GRCm39)	missense	probably damaging	1.00
R9108:Tenm3	UTSW	8	48,766,271 (GRCm39)	critical splice donor site	probably null
R9142:Tenm3	UTSW	8	48,788,548 (GRCm39)	missense	unknown
R9231:Tenm3	UTSW	8	48,689,231 (GRCm39)	missense	probably damaging	1.00
R9309:Tenm3	UTSW	8	48,751,972 (GRCm39)	missense	probably damaging	0.99
R9310:Tenm3	UTSW	8	49,008,935 (GRCm39)	unclassified	probably benign
R9336:Tenm3	UTSW	8	48,870,115 (GRCm39)	missense	probably damaging	1.00
R9373:Tenm3	UTSW	8	48,752,690 (GRCm39)	missense	probably damaging	1.00
R9393:Tenm3	UTSW	8	49,127,559 (GRCm39)	missense	probably damaging	0.99
R9509:Tenm3	UTSW	8	48,766,292 (GRCm39)	nonsense	probably null
R9575:Tenm3	UTSW	8	48,688,796 (GRCm39)	missense	possibly damaging	0.94
R9698:Tenm3	UTSW	8	48,689,246 (GRCm39)	missense	probably damaging	1.00
R9722:Tenm3	UTSW	8	48,753,849 (GRCm39)	missense	probably benign	0.00
R9788:Tenm3	UTSW	8	48,788,596 (GRCm39)	missense	probably benign	0.02
X0010:Tenm3	UTSW	8	48,740,864 (GRCm39)	missense	probably damaging	0.98
X0025:Tenm3	UTSW	8	48,689,512 (GRCm39)	missense	probably damaging	1.00
Z1177:Tenm3	UTSW	8	48,729,815 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- AAAGCCCACTGTTGCCATGG -3'
(R):5'- CACTCTGTACATTGCAGATCTGGG -3'

Sequencing Primer
(F):5'- CCACTGTTGCCATGGTAAGTAAAC -3'
(R):5'- AATATCAGGATCCGGGCCGTTTC -3'

Posted On

2014-06-23