Mutagenetix > Incidental Mutation

Incidental Mutation 'R1804:Fcgbp'

203380

Institutional Source

Beutler Lab

Gene Symbol

Fcgbp

Ensembl Gene

ENSMUSG00000047730

Gene Name

Fc fragment of IgG binding protein

Synonyms

A430096B05Rik

MMRRC Submission

039834-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1804 (G1)

Quality Score

132

Status

Validated

Chromosome

Chromosomal Location

27770661-27820287 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 27785564 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Arginine at position 334 (C334R)

Ref Sequence

ENSEMBL: ENSMUSP00000114271 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000076648] [ENSMUST00000138392]

AlphaFold

E9Q0B5

Predicted Effect

probably benign
Transcript: ENSMUST00000076648
AA Change: C334R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000075945
Gene: ENSMUSG00000047730
AA Change: C334R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	1.2e-12	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	6.85e-35	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	4.7e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.7e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	5e-12	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000138392
AA Change: C334R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000114271
Gene: ENSMUSG00000047730
AA Change: C334R

Domain	Start	End	E-Value	Type
signal peptide	1	26	N/A	INTRINSIC
FOLN	27	49	2.3e-4	SMART
VWD	46	211	5.26e-45	SMART
low complexity region	226	237	N/A	INTRINSIC
C8	251	326	1.17e-34	SMART
Pfam:TIL	329	383	8.4e-13	PFAM
VWC	385	431	2.34e-1	SMART
FOLN	418	441	3.48e1	SMART
VWD	438	603	7.99e-36	SMART
C8	642	717	1.4e-32	SMART
Pfam:TIL	720	773	3.3e-14	PFAM
VWC	775	829	9.42e-1	SMART
VWD	824	990	7.86e-44	SMART
C8	1034	1109	1.66e-34	SMART
Pfam:TIL	1112	1165	6.9e-13	PFAM
VWC	1167	1225	9.8e-3	SMART
FOLN	1198	1220	9.55e-1	SMART
FOLN	1224	1246	2.41e0	SMART
VWD	1243	1411	6.59e-37	SMART
C8	1451	1527	5.6e-32	SMART
low complexity region	1541	1551	N/A	INTRINSIC
EGF_like	1558	1581	6.15e1	SMART
VWC	1589	1682	1.6e-2	SMART
VWD	1640	1807	5.15e-39	SMART
C8	1839	1914	4.62e-33	SMART
EGF_like	1942	1965	4.46e1	SMART
VWC	1972	2064	1.92e-1	SMART
VWD	2024	2180	6.34e-39	SMART
low complexity region	2201	2214	N/A	INTRINSIC
C8	2221	2296	3.7e-32	SMART
Pfam:TIL	2299	2352	1e-11	PFAM
VWC	2354	2413	8.29e-1	SMART
FOLN	2385	2407	4.96e1	SMART
VWD	2404	2566	1.89e-5	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000140004

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 97.4%
3x: 96.7%
10x: 94.5%
20x: 89.8%

Validation Efficiency

96% (77/80)

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700056E22Rik	A	G	1: 183,765,400 (GRCm39)	Y220H	probably benign	Het
4930579C12Rik	T	C	9: 89,034,113 (GRCm39)		noncoding transcript	Het
Abcc8	T	C	7: 45,769,903 (GRCm39)	S871G	probably benign	Het
Acly	T	C	11: 100,406,731 (GRCm39)	Y288C	probably damaging	Het
Adgrb1	T	A	15: 74,401,389 (GRCm39)	D128E	probably damaging	Het
Alms1	C	T	6: 85,598,257 (GRCm39)	Q1497*	probably null	Het
Bltp2	A	G	11: 78,164,295 (GRCm39)	H1165R	probably damaging	Het
Cacna1c	G	A	6: 118,664,007 (GRCm39)	T688M	probably damaging	Het
Ccdc7a	A	T	8: 129,715,247 (GRCm39)	L279*	probably null	Het
Cep135	A	G	5: 76,784,779 (GRCm39)	E958G	probably benign	Het
Clec4n	G	T	6: 123,206,981 (GRCm39)	V2L	possibly damaging	Het
Col28a1	C	T	6: 8,164,612 (GRCm39)		probably null	Het
Dcaf5	A	G	12: 80,386,603 (GRCm39)	S508P	probably benign	Het
Dlgap2	C	A	8: 14,777,809 (GRCm39)	N351K	possibly damaging	Het
Dnah8	T	A	17: 30,927,381 (GRCm39)	Y1346N	probably benign	Het
Dqx1	T	C	6: 83,037,303 (GRCm39)	V322A	probably damaging	Het
Ebf3	A	C	7: 136,802,250 (GRCm39)	L412V	possibly damaging	Het
Epha5	T	C	5: 84,479,674 (GRCm39)	N110S	probably benign	Het
Glp1r	T	A	17: 31,149,687 (GRCm39)		probably null	Het
Gm4952	G	T	19: 12,595,784 (GRCm39)	R58L	probably damaging	Het
Gm7579	G	A	7: 141,765,675 (GRCm39)	C27Y	unknown	Het
Golm1	T	A	13: 59,790,203 (GRCm39)		probably null	Het
Gucy2g	T	A	19: 55,198,741 (GRCm39)	I801F	probably benign	Het
H2-D1	T	C	17: 35,482,528 (GRCm39)	Y83H	probably damaging	Het
Homez	A	T	14: 55,094,598 (GRCm39)	I19N	probably damaging	Het
Hoxa5	T	C	6: 52,179,628 (GRCm39)	K249R	probably damaging	Het
Hsd17b4	A	T	18: 50,311,051 (GRCm39)	N550Y	probably damaging	Het
Ipo4	A	T	14: 55,866,913 (GRCm39)	N668K	probably damaging	Het
Kcnh8	GAGACCAACGAGCAGCTGATGCTTCAGA	GAGA	17: 53,032,934 (GRCm39)	74	probably benign	Het
Klb	A	G	5: 65,537,196 (GRCm39)	D842G	probably damaging	Het
Minar1	T	A	9: 89,485,152 (GRCm39)	M82L	possibly damaging	Het
Mmp21	G	T	7: 133,280,611 (GRCm39)	P120T	probably benign	Het
Mroh7	T	A	4: 106,551,589 (GRCm39)	I918F	possibly damaging	Het
Muc5b	A	G	7: 141,417,517 (GRCm39)	T3488A	possibly damaging	Het
Npc1	C	T	18: 12,356,145 (GRCm39)	C42Y	probably damaging	Het
Ogdh	A	G	11: 6,288,565 (GRCm39)	Y214C	probably damaging	Het
Or2q1	G	A	6: 42,795,155 (GRCm39)	C250Y	possibly damaging	Het
Or4k15c	A	T	14: 50,321,359 (GRCm39)	W260R	probably damaging	Het
Or4k35	T	C	2: 111,100,275 (GRCm39)	M146V	probably benign	Het
Or5al1	G	T	2: 85,990,417 (GRCm39)	T99N	probably benign	Het
Or8d23	A	G	9: 38,841,946 (GRCm39)	T160A	possibly damaging	Het
Phtf1	A	G	3: 103,894,883 (GRCm39)		probably benign	Het
Plb1	A	G	5: 32,511,041 (GRCm39)	N1302S	possibly damaging	Het
Prex2	A	G	1: 11,202,566 (GRCm39)	K492E	probably damaging	Het
Prkaa1	A	G	15: 5,208,259 (GRCm39)	D509G	probably benign	Het
Rims2	C	T	15: 39,300,439 (GRCm39)	Q57*	probably null	Het
Rnf40	T	C	7: 127,195,120 (GRCm39)	V411A	possibly damaging	Het
Rraga	A	G	4: 86,494,681 (GRCm39)	I176V	probably damaging	Het
Rrm2	T	C	12: 24,758,611 (GRCm39)	I51T	probably benign	Het
Serpina3a	T	A	12: 104,084,675 (GRCm39)		probably benign	Het
Skint7	T	C	4: 111,839,209 (GRCm39)	W168R	probably damaging	Het
Slc27a4	A	G	2: 29,701,279 (GRCm39)	M357V	probably benign	Het
Slc4a3	A	G	1: 75,528,361 (GRCm39)	H452R	probably damaging	Het
Smc1b	A	T	15: 85,011,991 (GRCm39)	I127K	possibly damaging	Het
Snap91	T	A	9: 86,665,470 (GRCm39)	M383L	probably benign	Het
Taf6l	A	T	19: 8,750,998 (GRCm39)	L52Q	probably damaging	Het
Tas1r3	G	A	4: 155,944,927 (GRCm39)	R765C	probably damaging	Het
Tas2r124	A	G	6: 132,732,488 (GRCm39)	I266V	probably benign	Het
Tesk2	T	C	4: 116,657,818 (GRCm39)		probably benign	Het
Tmem131l	T	G	3: 83,817,786 (GRCm39)	Q1237P	possibly damaging	Het
Tmem67	A	G	4: 12,045,789 (GRCm39)		probably null	Het
Tnfaip8	T	A	18: 50,223,728 (GRCm39)	C179S	probably damaging	Het
Ush2a	G	A	1: 188,365,926 (GRCm39)		probably null	Het
Vps13b	A	T	15: 35,917,283 (GRCm39)	E3709V	probably damaging	Het
Wdr7	A	T	18: 63,998,511 (GRCm39)	S1153C	probably damaging	Het
Zc2hc1b	A	C	10: 13,047,012 (GRCm39)		probably benign	Het
Zfp438	A	G	18: 5,213,689 (GRCm39)	I423T	probably damaging	Het
Zfp592	C	A	7: 80,673,443 (GRCm39)	P136T	probably damaging	Het
Zfp783	T	A	6: 47,922,819 (GRCm39)		noncoding transcript	Het
Zfp804b	A	T	5: 6,821,756 (GRCm39)	S400T	possibly damaging	Het

Other mutations in Fcgbp

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00309:Fcgbp	APN	7	27,784,555 (GRCm39)	missense	probably damaging	1.00
IGL00331:Fcgbp	APN	7	27,800,966 (GRCm39)	splice site	probably benign
IGL00335:Fcgbp	APN	7	27,785,560 (GRCm39)	missense	possibly damaging	0.90
IGL00470:Fcgbp	APN	7	27,774,511 (GRCm39)	nonsense	probably null
IGL00491:Fcgbp	APN	7	27,792,827 (GRCm39)	missense	probably damaging	1.00
IGL00498:Fcgbp	APN	7	27,791,222 (GRCm39)	missense	probably damaging	1.00
IGL01296:Fcgbp	APN	7	27,789,072 (GRCm39)	missense	probably benign	0.15
IGL01582:Fcgbp	APN	7	27,793,067 (GRCm39)	missense	probably benign	0.19
IGL01929:Fcgbp	APN	7	27,803,388 (GRCm39)	missense	probably damaging	1.00
IGL02024:Fcgbp	APN	7	27,805,799 (GRCm39)	missense	probably damaging	1.00
IGL02027:Fcgbp	APN	7	27,774,629 (GRCm39)	missense	probably damaging	1.00
IGL02140:Fcgbp	APN	7	27,791,379 (GRCm39)	missense	probably damaging	1.00
IGL02162:Fcgbp	APN	7	27,774,660 (GRCm39)	missense	probably damaging	1.00
IGL02345:Fcgbp	APN	7	27,771,068 (GRCm39)	splice site	probably benign
IGL02377:Fcgbp	APN	7	27,806,395 (GRCm39)	missense	possibly damaging	0.67
IGL02389:Fcgbp	APN	7	27,774,596 (GRCm39)	missense	probably damaging	1.00
IGL02423:Fcgbp	APN	7	27,789,378 (GRCm39)	missense	probably benign	0.02
IGL02523:Fcgbp	APN	7	27,804,157 (GRCm39)	missense	possibly damaging	0.89
IGL02561:Fcgbp	APN	7	27,800,599 (GRCm39)	intron	probably benign
IGL02631:Fcgbp	APN	7	27,784,723 (GRCm39)	missense	probably damaging	1.00
IGL02716:Fcgbp	APN	7	27,800,859 (GRCm39)	missense	probably damaging	0.98
IGL02836:Fcgbp	APN	7	27,816,783 (GRCm39)	missense	possibly damaging	0.91
IGL02957:Fcgbp	APN	7	27,791,272 (GRCm39)	nonsense	probably null
IGL02971:Fcgbp	APN	7	27,800,898 (GRCm39)	missense	probably damaging	1.00
IGL03284:Fcgbp	APN	7	27,784,857 (GRCm39)	missense	possibly damaging	0.93
IGL03379:Fcgbp	APN	7	27,789,342 (GRCm39)	missense	possibly damaging	0.76
bilge	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R6548_fcgbp_365	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
swill	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
G1citation:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
IGL02796:Fcgbp	UTSW	7	27,800,576 (GRCm39)	intron	probably benign
PIT4486001:Fcgbp	UTSW	7	27,774,698 (GRCm39)	missense	possibly damaging	0.52
R0277:Fcgbp	UTSW	7	27,784,918 (GRCm39)	critical splice donor site	probably null
R0387:Fcgbp	UTSW	7	27,790,879 (GRCm39)	splice site	probably benign
R0586:Fcgbp	UTSW	7	27,789,138 (GRCm39)	missense	probably damaging	1.00
R0981:Fcgbp	UTSW	7	27,784,535 (GRCm39)	nonsense	probably null
R0987:Fcgbp	UTSW	7	27,793,599 (GRCm39)	missense	probably damaging	1.00
R1240:Fcgbp	UTSW	7	27,819,950 (GRCm39)	missense	probably damaging	1.00
R1394:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1395:Fcgbp	UTSW	7	27,792,804 (GRCm39)	missense	probably damaging	0.98
R1438:Fcgbp	UTSW	7	27,803,158 (GRCm39)	nonsense	probably null
R1474:Fcgbp	UTSW	7	27,791,273 (GRCm39)	missense	probably benign	0.00
R1521:Fcgbp	UTSW	7	27,774,585 (GRCm39)	missense	probably benign	0.00
R1740:Fcgbp	UTSW	7	27,800,674 (GRCm39)	missense	possibly damaging	0.87
R1750:Fcgbp	UTSW	7	27,792,868 (GRCm39)	nonsense	probably null
R1772:Fcgbp	UTSW	7	27,804,600 (GRCm39)	missense	possibly damaging	0.90
R1808:Fcgbp	UTSW	7	27,784,515 (GRCm39)	missense	probably benign	0.04
R1819:Fcgbp	UTSW	7	27,784,708 (GRCm39)	missense	probably benign	0.00
R1934:Fcgbp	UTSW	7	27,806,518 (GRCm39)	missense	probably damaging	1.00
R1972:Fcgbp	UTSW	7	27,793,617 (GRCm39)	missense	probably benign	0.11
R2051:Fcgbp	UTSW	7	27,819,785 (GRCm39)	missense	probably damaging	0.97
R2072:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2074:Fcgbp	UTSW	7	27,819,814 (GRCm39)	missense	probably damaging	0.98
R2124:Fcgbp	UTSW	7	27,791,444 (GRCm39)	missense	probably benign	0.03
R2155:Fcgbp	UTSW	7	27,806,628 (GRCm39)	missense	probably benign	0.00
R3015:Fcgbp	UTSW	7	27,774,838 (GRCm39)	splice site	probably benign
R3037:Fcgbp	UTSW	7	27,802,127 (GRCm39)	missense	possibly damaging	0.62
R3151:Fcgbp	UTSW	7	27,816,665 (GRCm39)	missense	probably damaging	1.00
R3176:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3177:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3276:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3277:Fcgbp	UTSW	7	27,791,086 (GRCm39)	missense	probably damaging	0.99
R3623:Fcgbp	UTSW	7	27,800,701 (GRCm39)	missense	probably damaging	1.00
R3730:Fcgbp	UTSW	7	27,784,882 (GRCm39)	missense	possibly damaging	0.82
R3935:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R3936:Fcgbp	UTSW	7	27,774,824 (GRCm39)	missense	probably benign	0.00
R4041:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	probably benign	0.01
R4056:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4057:Fcgbp	UTSW	7	27,803,541 (GRCm39)	missense	probably benign	0.09
R4705:Fcgbp	UTSW	7	27,806,721 (GRCm39)	missense	probably benign	0.44
R4708:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4710:Fcgbp	UTSW	7	27,794,386 (GRCm39)	missense	probably benign	0.00
R4779:Fcgbp	UTSW	7	27,794,362 (GRCm39)	missense	probably damaging	1.00
R4820:Fcgbp	UTSW	7	27,813,383 (GRCm39)	missense	probably damaging	1.00
R4863:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.33
R4926:Fcgbp	UTSW	7	27,785,660 (GRCm39)	missense	probably damaging	0.99
R4947:Fcgbp	UTSW	7	27,789,237 (GRCm39)	missense	probably benign	0.00
R4979:Fcgbp	UTSW	7	27,816,995 (GRCm39)	missense	probably benign	0.06
R5002:Fcgbp	UTSW	7	27,785,528 (GRCm39)	splice site	probably null
R5219:Fcgbp	UTSW	7	27,803,510 (GRCm39)	missense	probably damaging	1.00
R5241:Fcgbp	UTSW	7	27,784,624 (GRCm39)	missense	probably damaging	1.00
R5301:Fcgbp	UTSW	7	27,793,099 (GRCm39)	missense	possibly damaging	0.93
R5306:Fcgbp	UTSW	7	27,791,243 (GRCm39)	missense	probably damaging	1.00
R5335:Fcgbp	UTSW	7	27,789,159 (GRCm39)	missense	probably damaging	1.00
R5399:Fcgbp	UTSW	7	27,804,480 (GRCm39)	missense	probably benign	0.05
R5418:Fcgbp	UTSW	7	27,784,738 (GRCm39)	missense	probably damaging	1.00
R5527:Fcgbp	UTSW	7	27,793,060 (GRCm39)	missense	probably benign
R5583:Fcgbp	UTSW	7	27,791,004 (GRCm39)	missense	probably damaging	1.00
R5698:Fcgbp	UTSW	7	27,791,447 (GRCm39)	missense	possibly damaging	0.95
R5780:Fcgbp	UTSW	7	27,784,643 (GRCm39)	missense	probably benign	0.02
R5813:Fcgbp	UTSW	7	27,800,919 (GRCm39)	missense	possibly damaging	0.64
R5910:Fcgbp	UTSW	7	27,784,928 (GRCm39)	splice site	probably benign
R5936:Fcgbp	UTSW	7	27,786,117 (GRCm39)	missense	probably damaging	0.98
R5992:Fcgbp	UTSW	7	27,819,959 (GRCm39)	missense	probably benign	0.05
R6091:Fcgbp	UTSW	7	27,804,390 (GRCm39)	missense	possibly damaging	0.90
R6372:Fcgbp	UTSW	7	27,806,433 (GRCm39)	missense	probably damaging	1.00
R6488:Fcgbp	UTSW	7	27,792,963 (GRCm39)	missense	probably damaging	0.96
R6548:Fcgbp	UTSW	7	27,791,343 (GRCm39)	missense	probably benign	0.00
R6553:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6585:Fcgbp	UTSW	7	27,813,404 (GRCm39)	missense	possibly damaging	0.79
R6695:Fcgbp	UTSW	7	27,785,695 (GRCm39)	nonsense	probably null
R6711:Fcgbp	UTSW	7	27,789,098 (GRCm39)	missense	probably damaging	0.99
R6803:Fcgbp	UTSW	7	27,802,637 (GRCm39)	missense	probably benign	0.00
R6822:Fcgbp	UTSW	7	27,806,781 (GRCm39)	missense	probably damaging	1.00
R6907:Fcgbp	UTSW	7	27,784,443 (GRCm39)	missense	probably damaging	1.00
R6912:Fcgbp	UTSW	7	27,789,129 (GRCm39)	missense	probably benign	0.15
R6924:Fcgbp	UTSW	7	27,793,248 (GRCm39)	missense	probably benign
R6943:Fcgbp	UTSW	7	27,791,477 (GRCm39)	missense	probably benign	0.22
R7060:Fcgbp	UTSW	7	27,791,358 (GRCm39)	missense	probably benign	0.20
R7103:Fcgbp	UTSW	7	27,784,387 (GRCm39)	missense	probably benign	0.00
R7208:Fcgbp	UTSW	7	27,803,446 (GRCm39)	missense	probably benign	0.01
R7291:Fcgbp	UTSW	7	27,800,817 (GRCm39)	missense	probably benign	0.00
R7301:Fcgbp	UTSW	7	27,792,861 (GRCm39)	missense	possibly damaging	0.65
R7404:Fcgbp	UTSW	7	27,800,932 (GRCm39)	missense	probably damaging	1.00
R7426:Fcgbp	UTSW	7	27,785,949 (GRCm39)	missense	probably benign	0.00
R7459:Fcgbp	UTSW	7	27,806,710 (GRCm39)	missense	possibly damaging	0.65
R7475:Fcgbp	UTSW	7	27,802,401 (GRCm39)	missense	probably damaging	0.99
R7505:Fcgbp	UTSW	7	27,789,099 (GRCm39)	missense	probably damaging	0.97
R7517:Fcgbp	UTSW	7	27,784,794 (GRCm39)	missense	probably damaging	1.00
R7519:Fcgbp	UTSW	7	27,785,724 (GRCm39)	missense	probably damaging	1.00
R7524:Fcgbp	UTSW	7	27,802,391 (GRCm39)	missense	probably damaging	1.00
R7649:Fcgbp	UTSW	7	27,790,928 (GRCm39)	missense	possibly damaging	0.88
R7782:Fcgbp	UTSW	7	27,784,460 (GRCm39)	nonsense	probably null
R7820:Fcgbp	UTSW	7	27,819,784 (GRCm39)	missense	probably benign	0.01
R7831:Fcgbp	UTSW	7	27,806,404 (GRCm39)	missense	probably damaging	0.98
R7835:Fcgbp	UTSW	7	27,816,632 (GRCm39)	missense	possibly damaging	0.64
R7947:Fcgbp	UTSW	7	27,803,595 (GRCm39)	critical splice donor site	probably null
R8086:Fcgbp	UTSW	7	27,813,389 (GRCm39)	missense	probably damaging	1.00
R8137:Fcgbp	UTSW	7	27,804,496 (GRCm39)	missense	probably damaging	1.00
R8154:Fcgbp	UTSW	7	27,784,507 (GRCm39)	missense	probably benign	0.00
R8169:Fcgbp	UTSW	7	27,784,919 (GRCm39)	critical splice donor site	probably null
R8176:Fcgbp	UTSW	7	27,791,174 (GRCm39)	missense	possibly damaging	0.88
R8193:Fcgbp	UTSW	7	27,804,276 (GRCm39)	missense	probably damaging	1.00
R8313:Fcgbp	UTSW	7	27,785,769 (GRCm39)	missense	probably benign	0.00
R8350:Fcgbp	UTSW	7	27,793,614 (GRCm39)	missense	probably benign	0.02
R8382:Fcgbp	UTSW	7	27,816,762 (GRCm39)	missense	probably benign	0.00
R8393:Fcgbp	UTSW	7	27,806,815 (GRCm39)	missense	probably benign	0.18
R8438:Fcgbp	UTSW	7	27,789,231 (GRCm39)	missense	probably benign	0.25
R8489:Fcgbp	UTSW	7	27,804,435 (GRCm39)	missense	possibly damaging	0.94
R8495:Fcgbp	UTSW	7	27,785,978 (GRCm39)	missense	probably damaging	1.00
R8707:Fcgbp	UTSW	7	27,819,920 (GRCm39)	missense	probably benign	0.01
R8736:Fcgbp	UTSW	7	27,805,621 (GRCm39)	missense	probably benign	0.05
R8816:Fcgbp	UTSW	7	27,784,412 (GRCm39)	missense	probably benign	0.09
R8905:Fcgbp	UTSW	7	27,785,934 (GRCm39)	missense	probably damaging	1.00
R9031:Fcgbp	UTSW	7	27,790,908 (GRCm39)	missense	possibly damaging	0.89
R9063:Fcgbp	UTSW	7	27,791,277 (GRCm39)	missense	probably damaging	1.00
R9180:Fcgbp	UTSW	7	27,803,198 (GRCm39)	nonsense	probably null
R9262:Fcgbp	UTSW	7	27,819,952 (GRCm39)	missense	probably damaging	1.00
R9439:Fcgbp	UTSW	7	27,803,436 (GRCm39)	missense	possibly damaging	0.60
R9526:Fcgbp	UTSW	7	27,790,937 (GRCm39)	missense	probably damaging	1.00
R9603:Fcgbp	UTSW	7	27,802,563 (GRCm39)	missense	probably damaging	1.00
R9635:Fcgbp	UTSW	7	27,800,832 (GRCm39)	missense	probably benign	0.40
R9703:Fcgbp	UTSW	7	27,806,400 (GRCm39)	missense	probably damaging	0.98
R9711:Fcgbp	UTSW	7	27,793,000 (GRCm39)	missense	probably benign	0.00
R9733:Fcgbp	UTSW	7	27,803,012 (GRCm39)	missense	probably damaging	1.00
RF002:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
X0028:Fcgbp	UTSW	7	27,803,445 (GRCm39)	missense	possibly damaging	0.48
Z1186:Fcgbp	UTSW	7	27,791,072 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,789,180 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,785,616 (GRCm39)	missense	probably benign
Z1186:Fcgbp	UTSW	7	27,803,309 (GRCm39)	missense	probably benign	0.09
Z1186:Fcgbp	UTSW	7	27,792,770 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- AGATTCTGCAAGGGCTTGGAAG -3'
(R):5'- TCAAACACTTCCTGACCCGG -3'

Sequencing Primer
(F):5'- GTGAAAGTCTCAGGATTTGCCCAC -3'
(R):5'- TGAGACAGGCACACAATC -3'

Posted On

2014-06-23