Incidental Mutation 'R1861:Nwd2'
| ID |
203899 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nwd2
|
| Ensembl Gene |
ENSMUSG00000090061 |
| Gene Name |
NACHT and WD repeat domain containing 2 |
| Synonyms |
3110047P20Rik, B830017A01Rik |
| MMRRC Submission |
039884-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R1861 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
63806446-63967889 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 63962197 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 594
(S594P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000124712
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000159584]
[ENSMUST00000162166]
|
| AlphaFold |
Q6P5U7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000159584
AA Change: S594P
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000124712
Gene: ENSMUSG00000090061
AA Change: S594P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4062
|
42 |
145 |
1.5e-8 |
PFAM |
|
Blast:AAA
|
408 |
691 |
3e-29 |
BLAST |
|
WD40
|
939 |
995 |
1.06e2 |
SMART |
|
WD40
|
998 |
1037 |
8.96e-2 |
SMART |
|
Blast:WD40
|
1091 |
1126 |
9e-19 |
BLAST |
|
Blast:WD40
|
1129 |
1170 |
1e-17 |
BLAST |
|
Blast:WD40
|
1220 |
1260 |
3e-16 |
BLAST |
|
WD40
|
1263 |
1302 |
3.4e-2 |
SMART |
|
WD40
|
1347 |
1385 |
2.65e1 |
SMART |
|
WD40
|
1386 |
1425 |
1.58e2 |
SMART |
|
Blast:WD40
|
1466 |
1507 |
3e-19 |
BLAST |
|
Blast:WD40
|
1606 |
1644 |
4e-18 |
BLAST |
|
Blast:KR
|
1686 |
1730 |
2e-16 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162166
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162757
|
| Meta Mutation Damage Score |
0.3352 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 92.0%
|
| Validation Efficiency |
97% (117/121) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930579C12Rik |
C |
A |
9: 89,034,884 (GRCm39) |
|
noncoding transcript |
Het |
| Abra |
C |
A |
15: 41,732,430 (GRCm39) |
R212L |
probably damaging |
Het |
| Actr1a |
T |
C |
19: 46,372,714 (GRCm39) |
E87G |
probably damaging |
Het |
| Adam26a |
A |
G |
8: 44,022,578 (GRCm39) |
V304A |
possibly damaging |
Het |
| Alg2 |
T |
A |
4: 47,471,670 (GRCm39) |
K379N |
probably benign |
Het |
| Alk |
G |
T |
17: 72,181,933 (GRCm39) |
|
probably benign |
Het |
| Aopep |
A |
G |
13: 63,163,597 (GRCm39) |
Y206C |
probably damaging |
Het |
| Arhgef17 |
A |
G |
7: 100,531,475 (GRCm39) |
Y331H |
probably damaging |
Het |
| Art3 |
A |
G |
5: 92,560,094 (GRCm39) |
|
probably benign |
Het |
| Asap1 |
G |
A |
15: 64,007,647 (GRCm39) |
|
probably benign |
Het |
| Atad2 |
A |
T |
15: 57,960,114 (GRCm39) |
|
probably null |
Het |
| Atp8b5 |
G |
A |
4: 43,372,906 (GRCm39) |
R1150H |
probably damaging |
Het |
| Bltp2 |
C |
T |
11: 78,178,755 (GRCm39) |
|
probably benign |
Het |
| Brdt |
T |
C |
5: 107,507,324 (GRCm39) |
S575P |
probably benign |
Het |
| Capn3 |
T |
A |
2: 120,316,963 (GRCm39) |
|
probably benign |
Het |
| Casd1 |
T |
A |
6: 4,640,951 (GRCm39) |
Y691N |
probably damaging |
Het |
| Ccdc127 |
T |
G |
13: 74,505,098 (GRCm39) |
H215Q |
possibly damaging |
Het |
| Cenpe |
T |
C |
3: 134,974,740 (GRCm39) |
L2300P |
probably damaging |
Het |
| Clasp1 |
T |
C |
1: 118,498,661 (GRCm39) |
F898L |
possibly damaging |
Het |
| Clcn1 |
C |
A |
6: 42,290,925 (GRCm39) |
P933Q |
possibly damaging |
Het |
| Cntn3 |
T |
A |
6: 102,222,032 (GRCm39) |
N489I |
probably benign |
Het |
| Col16a1 |
T |
C |
4: 129,955,517 (GRCm39) |
|
probably benign |
Het |
| Col24a1 |
G |
A |
3: 145,243,022 (GRCm39) |
|
probably null |
Het |
| Col8a2 |
C |
T |
4: 126,205,417 (GRCm39) |
|
probably benign |
Het |
| Cpd |
T |
C |
11: 76,675,208 (GRCm39) |
|
probably benign |
Het |
| Csmd3 |
A |
T |
15: 47,522,588 (GRCm39) |
C2694S |
probably damaging |
Het |
| Cyp2c40 |
T |
C |
19: 39,775,319 (GRCm39) |
Y311C |
probably benign |
Het |
| Dennd5b |
T |
A |
6: 148,969,760 (GRCm39) |
N231I |
probably damaging |
Het |
| Dgkh |
T |
A |
14: 78,816,232 (GRCm39) |
H936L |
probably benign |
Het |
| Dmtf1 |
T |
C |
5: 9,170,347 (GRCm39) |
|
probably null |
Het |
| Dnai2 |
T |
C |
11: 114,643,777 (GRCm39) |
V481A |
possibly damaging |
Het |
| Dnai3 |
T |
C |
3: 145,788,801 (GRCm39) |
Y260C |
probably damaging |
Het |
| Dpyd |
T |
G |
3: 118,710,780 (GRCm39) |
V396G |
probably damaging |
Het |
| Elmo3 |
A |
G |
8: 106,035,213 (GRCm39) |
D448G |
probably damaging |
Het |
| Emsy |
A |
T |
7: 98,290,822 (GRCm39) |
V100E |
probably damaging |
Het |
| Erbb2 |
T |
C |
11: 98,303,563 (GRCm39) |
|
probably null |
Het |
| Faah |
T |
C |
4: 115,865,432 (GRCm39) |
K85R |
probably benign |
Het |
| Fam149a |
A |
T |
8: 45,792,399 (GRCm39) |
Y686* |
probably null |
Het |
| Fat4 |
T |
C |
3: 39,064,633 (GRCm39) |
V4863A |
probably benign |
Het |
| Fbxl8 |
A |
G |
8: 105,995,561 (GRCm39) |
T358A |
probably damaging |
Het |
| Fcgbpl1 |
A |
G |
7: 27,854,157 (GRCm39) |
Y1707C |
probably damaging |
Het |
| Fgfr3 |
A |
G |
5: 33,887,090 (GRCm39) |
T165A |
probably damaging |
Het |
| Fnbp1l |
A |
T |
3: 122,354,581 (GRCm39) |
H180Q |
probably damaging |
Het |
| Gm8180 |
T |
A |
14: 44,021,196 (GRCm39) |
H4L |
probably benign |
Het |
| Gon4l |
T |
C |
3: 88,802,794 (GRCm39) |
V1135A |
probably damaging |
Het |
| Gstcd |
G |
T |
3: 132,688,868 (GRCm39) |
N627K |
probably damaging |
Het |
| Gtf2a1l |
G |
A |
17: 89,022,382 (GRCm39) |
V458I |
probably damaging |
Het |
| Gtf3c3 |
T |
C |
1: 54,477,997 (GRCm39) |
E26G |
possibly damaging |
Het |
| Hrct1 |
A |
T |
4: 43,727,404 (GRCm39) |
T15S |
probably benign |
Het |
| Ift122 |
C |
A |
6: 115,868,889 (GRCm39) |
R459S |
probably damaging |
Het |
| Irf1 |
T |
A |
11: 53,665,183 (GRCm39) |
C187S |
possibly damaging |
Het |
| Kcnh7 |
A |
G |
2: 62,607,736 (GRCm39) |
V615A |
probably damaging |
Het |
| Kif1c |
T |
C |
11: 70,594,168 (GRCm39) |
S61P |
probably damaging |
Het |
| Mamdc2 |
T |
C |
19: 23,336,517 (GRCm39) |
T331A |
probably damaging |
Het |
| Mark2 |
T |
C |
19: 7,268,128 (GRCm39) |
D25G |
possibly damaging |
Het |
| Me2 |
T |
C |
18: 73,918,785 (GRCm39) |
D432G |
probably benign |
Het |
| Mfap3 |
T |
C |
11: 57,419,032 (GRCm39) |
V64A |
probably benign |
Het |
| Nadk2 |
T |
A |
15: 9,108,399 (GRCm39) |
M416K |
probably benign |
Het |
| Ndufs1 |
C |
T |
1: 63,186,576 (GRCm39) |
G631D |
probably benign |
Het |
| Nomo1 |
G |
A |
7: 45,727,525 (GRCm39) |
V1055I |
probably benign |
Het |
| Nuggc |
T |
A |
14: 65,879,450 (GRCm39) |
|
probably benign |
Het |
| Or13c3 |
T |
A |
4: 52,856,373 (GRCm39) |
I47L |
probably benign |
Het |
| Or4a27 |
T |
G |
2: 88,559,674 (GRCm39) |
I90L |
probably damaging |
Het |
| Or4b1b |
C |
A |
2: 90,112,502 (GRCm39) |
C139F |
probably damaging |
Het |
| Or5b113 |
T |
A |
19: 13,342,705 (GRCm39) |
S238T |
possibly damaging |
Het |
| Or6p1 |
T |
C |
1: 174,258,657 (GRCm39) |
I221T |
probably damaging |
Het |
| Or8c10 |
C |
T |
9: 38,278,902 (GRCm39) |
S10L |
probably benign |
Het |
| Pakap |
A |
G |
4: 57,709,468 (GRCm39) |
I138V |
probably damaging |
Het |
| Pcyt2 |
G |
A |
11: 120,501,968 (GRCm39) |
P332S |
probably benign |
Het |
| Phaf1 |
A |
G |
8: 105,966,703 (GRCm39) |
E150G |
probably null |
Het |
| Phf14 |
A |
T |
6: 11,987,610 (GRCm39) |
M630L |
probably benign |
Het |
| Piezo1 |
T |
C |
8: 123,222,489 (GRCm39) |
N919S |
possibly damaging |
Het |
| Pif1 |
A |
T |
9: 65,496,735 (GRCm39) |
I283F |
probably damaging |
Het |
| Pknox2 |
G |
A |
9: 36,834,957 (GRCm39) |
H171Y |
probably damaging |
Het |
| Pramel17 |
A |
T |
4: 101,694,135 (GRCm39) |
D249E |
probably benign |
Het |
| Prkg2 |
T |
A |
5: 99,095,275 (GRCm39) |
D632V |
probably damaging |
Het |
| Prr29 |
G |
A |
11: 106,266,264 (GRCm39) |
A6T |
probably damaging |
Het |
| Rims1 |
T |
A |
1: 22,635,639 (GRCm39) |
Y114F |
probably damaging |
Het |
| Ryr1 |
A |
T |
7: 28,708,977 (GRCm39) |
D4796E |
unknown |
Het |
| Scnn1b |
G |
A |
7: 121,513,484 (GRCm39) |
C399Y |
probably damaging |
Het |
| Scp2 |
T |
C |
4: 107,948,518 (GRCm39) |
Y153C |
probably damaging |
Het |
| Sema3d |
A |
G |
5: 12,547,570 (GRCm39) |
K164R |
probably benign |
Het |
| Siglecf |
A |
G |
7: 43,001,648 (GRCm39) |
T153A |
probably benign |
Het |
| Siglecf |
A |
G |
7: 43,004,967 (GRCm39) |
N399S |
probably benign |
Het |
| Skint2 |
T |
C |
4: 112,504,315 (GRCm39) |
|
probably benign |
Het |
| Slc22a8 |
G |
A |
19: 8,583,503 (GRCm39) |
R236H |
probably damaging |
Het |
| Slc25a40 |
T |
A |
5: 8,492,431 (GRCm39) |
|
probably null |
Het |
| Slc26a5 |
T |
C |
5: 22,021,956 (GRCm39) |
D490G |
possibly damaging |
Het |
| Slc26a7 |
G |
T |
4: 14,522,873 (GRCm39) |
D482E |
probably benign |
Het |
| Smarca2 |
A |
T |
19: 26,601,284 (GRCm39) |
M77L |
probably benign |
Het |
| Sos2 |
A |
G |
12: 69,664,137 (GRCm39) |
L449P |
probably damaging |
Het |
| Spaca1 |
A |
G |
4: 34,044,206 (GRCm39) |
V96A |
probably damaging |
Het |
| Spata31d1b |
T |
A |
13: 59,865,150 (GRCm39) |
I766N |
possibly damaging |
Het |
| Specc1l |
T |
C |
10: 75,145,693 (GRCm39) |
Y1113H |
probably damaging |
Het |
| Speg |
A |
G |
1: 75,365,649 (GRCm39) |
R677G |
probably damaging |
Het |
| Taf5l |
A |
T |
8: 124,724,729 (GRCm39) |
D363E |
probably damaging |
Het |
| Tex56 |
A |
T |
13: 35,116,490 (GRCm39) |
I80F |
possibly damaging |
Het |
| Tmem208 |
A |
G |
8: 106,061,438 (GRCm39) |
K155E |
possibly damaging |
Het |
| Tppp2 |
A |
C |
14: 52,158,062 (GRCm39) |
N169T |
probably benign |
Het |
| Trrap |
T |
A |
5: 144,752,727 (GRCm39) |
|
probably null |
Het |
| Ttll6 |
T |
A |
11: 96,029,700 (GRCm39) |
Y204* |
probably null |
Het |
| Ttn |
A |
T |
2: 76,602,992 (GRCm39) |
I18410K |
probably benign |
Het |
| V1rd19 |
T |
A |
7: 23,703,149 (GRCm39) |
V205D |
probably damaging |
Het |
| Vdac3 |
A |
T |
8: 23,070,515 (GRCm39) |
I132K |
possibly damaging |
Het |
| Vmn2r95 |
T |
G |
17: 18,672,530 (GRCm39) |
C756G |
probably damaging |
Het |
| Zc3h15 |
A |
G |
2: 83,494,334 (GRCm39) |
T421A |
unknown |
Het |
| Zc3hc1 |
T |
C |
6: 30,374,837 (GRCm39) |
T235A |
probably benign |
Het |
| Zcchc14 |
A |
G |
8: 122,335,990 (GRCm39) |
|
probably benign |
Het |
| Zfp318 |
T |
A |
17: 46,722,366 (GRCm39) |
N1456K |
possibly damaging |
Het |
| Zfp606 |
A |
G |
7: 12,214,858 (GRCm39) |
|
probably benign |
Het |
| Zfp811 |
T |
A |
17: 33,016,399 (GRCm39) |
H546L |
probably damaging |
Het |
| Zfp94 |
A |
T |
7: 24,008,541 (GRCm39) |
Y33N |
probably damaging |
Het |
| Zfyve9 |
G |
T |
4: 108,539,492 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Nwd2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00325:Nwd2
|
APN |
5 |
63,962,818 (GRCm39) |
missense |
probably benign |
|
|
IGL01111:Nwd2
|
APN |
5 |
63,964,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01152:Nwd2
|
APN |
5 |
63,963,872 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01307:Nwd2
|
APN |
5 |
63,965,626 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01449:Nwd2
|
APN |
5 |
63,962,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01624:Nwd2
|
APN |
5 |
63,964,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01997:Nwd2
|
APN |
5 |
63,961,938 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02007:Nwd2
|
APN |
5 |
63,962,042 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02143:Nwd2
|
APN |
5 |
63,948,996 (GRCm39) |
splice site |
probably null |
|
|
IGL02184:Nwd2
|
APN |
5 |
63,963,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02379:Nwd2
|
APN |
5 |
63,962,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02489:Nwd2
|
APN |
5 |
63,962,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02580:Nwd2
|
APN |
5 |
63,965,512 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02682:Nwd2
|
APN |
5 |
63,962,020 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02891:Nwd2
|
APN |
5 |
63,882,570 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03135:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Nwd2
|
APN |
5 |
63,963,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0113:Nwd2
|
UTSW |
5 |
63,965,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0172:Nwd2
|
UTSW |
5 |
63,963,712 (GRCm39) |
missense |
probably benign |
0.44 |
|
R0196:Nwd2
|
UTSW |
5 |
63,963,694 (GRCm39) |
missense |
probably benign |
0.37 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0239:Nwd2
|
UTSW |
5 |
63,957,467 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0309:Nwd2
|
UTSW |
5 |
63,964,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Nwd2
|
UTSW |
5 |
63,962,341 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0335:Nwd2
|
UTSW |
5 |
63,962,116 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0384:Nwd2
|
UTSW |
5 |
63,963,025 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0496:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0497:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0498:Nwd2
|
UTSW |
5 |
63,963,686 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0505:Nwd2
|
UTSW |
5 |
63,962,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Nwd2
|
UTSW |
5 |
63,948,928 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0762:Nwd2
|
UTSW |
5 |
63,957,757 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0835:Nwd2
|
UTSW |
5 |
63,957,473 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0926:Nwd2
|
UTSW |
5 |
63,965,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0948:Nwd2
|
UTSW |
5 |
63,964,655 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1015:Nwd2
|
UTSW |
5 |
63,964,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1086:Nwd2
|
UTSW |
5 |
63,963,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1186:Nwd2
|
UTSW |
5 |
63,807,367 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1305:Nwd2
|
UTSW |
5 |
63,902,540 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1542:Nwd2
|
UTSW |
5 |
63,964,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1548:Nwd2
|
UTSW |
5 |
63,957,525 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Nwd2
|
UTSW |
5 |
63,957,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1636:Nwd2
|
UTSW |
5 |
63,964,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1658:Nwd2
|
UTSW |
5 |
63,964,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Nwd2
|
UTSW |
5 |
63,965,614 (GRCm39) |
missense |
probably benign |
|
|
R1800:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1813:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1889:Nwd2
|
UTSW |
5 |
63,965,009 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1896:Nwd2
|
UTSW |
5 |
63,962,753 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Nwd2
|
UTSW |
5 |
63,963,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1922:Nwd2
|
UTSW |
5 |
63,951,585 (GRCm39) |
missense |
probably benign |
|
|
R2258:Nwd2
|
UTSW |
5 |
63,962,499 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2292:Nwd2
|
UTSW |
5 |
63,962,917 (GRCm39) |
missense |
probably benign |
0.15 |
|
R2504:Nwd2
|
UTSW |
5 |
63,961,717 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2869:Nwd2
|
UTSW |
5 |
63,957,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2958:Nwd2
|
UTSW |
5 |
63,963,325 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3034:Nwd2
|
UTSW |
5 |
63,957,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3422:Nwd2
|
UTSW |
5 |
63,882,536 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3423:Nwd2
|
UTSW |
5 |
63,957,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3439:Nwd2
|
UTSW |
5 |
63,961,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4193:Nwd2
|
UTSW |
5 |
63,964,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4254:Nwd2
|
UTSW |
5 |
63,963,889 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R4384:Nwd2
|
UTSW |
5 |
63,963,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4707:Nwd2
|
UTSW |
5 |
63,951,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4713:Nwd2
|
UTSW |
5 |
63,961,803 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4735:Nwd2
|
UTSW |
5 |
63,965,594 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4744:Nwd2
|
UTSW |
5 |
63,964,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4795:Nwd2
|
UTSW |
5 |
63,962,776 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4835:Nwd2
|
UTSW |
5 |
63,965,189 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4839:Nwd2
|
UTSW |
5 |
63,962,893 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4896:Nwd2
|
UTSW |
5 |
63,962,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5017:Nwd2
|
UTSW |
5 |
63,807,484 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R5170:Nwd2
|
UTSW |
5 |
63,963,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5312:Nwd2
|
UTSW |
5 |
63,963,415 (GRCm39) |
nonsense |
probably null |
|
|
R5330:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5331:Nwd2
|
UTSW |
5 |
63,963,859 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5419:Nwd2
|
UTSW |
5 |
63,965,051 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5434:Nwd2
|
UTSW |
5 |
63,964,991 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5445:Nwd2
|
UTSW |
5 |
63,962,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Nwd2
|
UTSW |
5 |
63,882,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5788:Nwd2
|
UTSW |
5 |
63,965,114 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5907:Nwd2
|
UTSW |
5 |
63,963,326 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5959:Nwd2
|
UTSW |
5 |
63,965,413 (GRCm39) |
missense |
probably benign |
0.32 |
|
R6002:Nwd2
|
UTSW |
5 |
63,962,143 (GRCm39) |
missense |
probably benign |
|
|
R6027:Nwd2
|
UTSW |
5 |
63,965,563 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6082:Nwd2
|
UTSW |
5 |
63,962,374 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6163:Nwd2
|
UTSW |
5 |
63,963,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6172:Nwd2
|
UTSW |
5 |
63,964,249 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6334:Nwd2
|
UTSW |
5 |
63,957,596 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6447:Nwd2
|
UTSW |
5 |
63,964,898 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6649:Nwd2
|
UTSW |
5 |
63,882,527 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6855:Nwd2
|
UTSW |
5 |
63,961,794 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7034:Nwd2
|
UTSW |
5 |
63,962,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7168:Nwd2
|
UTSW |
5 |
63,964,837 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7326:Nwd2
|
UTSW |
5 |
63,957,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7561:Nwd2
|
UTSW |
5 |
63,964,434 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Nwd2
|
UTSW |
5 |
63,964,736 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7580:Nwd2
|
UTSW |
5 |
63,965,624 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7723:Nwd2
|
UTSW |
5 |
63,965,347 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7769:Nwd2
|
UTSW |
5 |
63,961,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8293:Nwd2
|
UTSW |
5 |
63,962,663 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8517:Nwd2
|
UTSW |
5 |
63,948,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8792:Nwd2
|
UTSW |
5 |
63,963,047 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8888:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8895:Nwd2
|
UTSW |
5 |
63,963,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8901:Nwd2
|
UTSW |
5 |
63,963,685 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Nwd2
|
UTSW |
5 |
63,963,440 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8920:Nwd2
|
UTSW |
5 |
63,948,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9052:Nwd2
|
UTSW |
5 |
63,961,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Nwd2
|
UTSW |
5 |
63,961,747 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9368:Nwd2
|
UTSW |
5 |
63,962,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9377:Nwd2
|
UTSW |
5 |
63,957,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9430:Nwd2
|
UTSW |
5 |
63,964,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Nwd2
|
UTSW |
5 |
63,964,568 (GRCm39) |
nonsense |
probably null |
|
|
R9661:Nwd2
|
UTSW |
5 |
63,957,780 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9736:Nwd2
|
UTSW |
5 |
63,951,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9795:Nwd2
|
UTSW |
5 |
63,964,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF020:Nwd2
|
UTSW |
5 |
63,963,066 (GRCm39) |
nonsense |
probably null |
|
|
X0023:Nwd2
|
UTSW |
5 |
63,964,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,963,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Nwd2
|
UTSW |
5 |
63,882,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nwd2
|
UTSW |
5 |
63,964,669 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Nwd2
|
UTSW |
5 |
63,962,327 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGTTTGTGCGGATCATCCTC -3'
(R):5'- CCATTTTGGCCATGGTGATG -3'
Sequencing Primer
(F):5'- GCGGATCATCCTCTCCACACTG -3'
(R):5'- TGGAGACCAGTTTCTGACCAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation