Incidental Mutation 'R1862:Ticrr'
| ID |
204028 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ticrr
|
| Ensembl Gene |
ENSMUSG00000046591 |
| Gene Name |
TOPBP1-interacting checkpoint and replication regulator |
| Synonyms |
5730590G19Rik |
| MMRRC Submission |
039885-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.947)
|
| Stock # |
R1862 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
79660196-79698148 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 79695207 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1607
(S1607P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041377
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035977]
[ENSMUST00000059836]
[ENSMUST00000178048]
[ENSMUST00000183846]
[ENSMUST00000184137]
[ENSMUST00000206591]
[ENSMUST00000206622]
|
| AlphaFold |
Q8BQ33 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000035977
AA Change: S1607P
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000041377
Gene: ENSMUSG00000046591
AA Change: S1607P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
23 |
31 |
N/A |
INTRINSIC |
|
Pfam:Treslin_N
|
211 |
1005 |
N/A |
PFAM |
|
low complexity region
|
1186 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1359 |
N/A |
INTRINSIC |
|
low complexity region
|
1472 |
1480 |
N/A |
INTRINSIC |
|
low complexity region
|
1496 |
1514 |
N/A |
INTRINSIC |
|
low complexity region
|
1630 |
1643 |
N/A |
INTRINSIC |
|
low complexity region
|
1694 |
1707 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000059836
|
| SMART Domains |
Protein: ENSMUSP00000061806
Gene: ENSMUSG00000050382
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
13 |
357 |
2.88e-143 |
SMART |
|
low complexity region
|
391 |
410 |
N/A |
INTRINSIC |
|
Blast:KISc
|
413 |
481 |
1e-19 |
BLAST |
|
Blast:KISc
|
482 |
518 |
3e-11 |
BLAST |
|
low complexity region
|
523 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
543 |
557 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
636 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
685 |
N/A |
INTRINSIC |
|
Blast:KISc
|
780 |
879 |
2e-15 |
BLAST |
|
low complexity region
|
927 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
993 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1061 |
N/A |
INTRINSIC |
|
coiled coil region
|
1113 |
1139 |
N/A |
INTRINSIC |
|
coiled coil region
|
1186 |
1205 |
N/A |
INTRINSIC |
|
low complexity region
|
1293 |
1304 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000178048
|
| SMART Domains |
Protein: ENSMUSP00000136993
Gene: ENSMUSG00000050382
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
13 |
357 |
2.88e-143 |
SMART |
|
low complexity region
|
391 |
410 |
N/A |
INTRINSIC |
|
Blast:KISc
|
413 |
481 |
1e-19 |
BLAST |
|
Blast:KISc
|
482 |
518 |
3e-11 |
BLAST |
|
low complexity region
|
523 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
543 |
557 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
636 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
685 |
N/A |
INTRINSIC |
|
Blast:KISc
|
780 |
879 |
2e-15 |
BLAST |
|
low complexity region
|
908 |
918 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
945 |
N/A |
INTRINSIC |
|
low complexity region
|
980 |
994 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1114 |
1140 |
N/A |
INTRINSIC |
|
coiled coil region
|
1187 |
1206 |
N/A |
INTRINSIC |
|
low complexity region
|
1294 |
1305 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000183846
|
| SMART Domains |
Protein: ENSMUSP00000139359
Gene: ENSMUSG00000050382
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
13 |
357 |
2.88e-143 |
SMART |
|
low complexity region
|
391 |
410 |
N/A |
INTRINSIC |
|
Blast:KISc
|
413 |
481 |
1e-19 |
BLAST |
|
Blast:KISc
|
482 |
518 |
3e-11 |
BLAST |
|
low complexity region
|
523 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
543 |
557 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
636 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
685 |
N/A |
INTRINSIC |
|
Blast:KISc
|
780 |
879 |
2e-15 |
BLAST |
|
low complexity region
|
908 |
918 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
945 |
N/A |
INTRINSIC |
|
low complexity region
|
980 |
994 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1062 |
N/A |
INTRINSIC |
|
coiled coil region
|
1114 |
1140 |
N/A |
INTRINSIC |
|
coiled coil region
|
1187 |
1206 |
N/A |
INTRINSIC |
|
low complexity region
|
1294 |
1305 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000184137
|
| SMART Domains |
Protein: ENSMUSP00000139224
Gene: ENSMUSG00000050382
| Domain | Start | End | E-Value | Type |
|---|
|
KISc
|
13 |
357 |
2.88e-143 |
SMART |
|
low complexity region
|
391 |
410 |
N/A |
INTRINSIC |
|
Blast:KISc
|
413 |
481 |
1e-19 |
BLAST |
|
Blast:KISc
|
482 |
518 |
3e-11 |
BLAST |
|
low complexity region
|
523 |
540 |
N/A |
INTRINSIC |
|
low complexity region
|
543 |
557 |
N/A |
INTRINSIC |
|
low complexity region
|
621 |
636 |
N/A |
INTRINSIC |
|
low complexity region
|
669 |
685 |
N/A |
INTRINSIC |
|
Blast:KISc
|
780 |
879 |
2e-15 |
BLAST |
|
low complexity region
|
927 |
944 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
993 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1061 |
N/A |
INTRINSIC |
|
coiled coil region
|
1113 |
1139 |
N/A |
INTRINSIC |
|
coiled coil region
|
1186 |
1205 |
N/A |
INTRINSIC |
|
low complexity region
|
1293 |
1304 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206591
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000206622
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 90.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
PHENOTYPE: Mice homozygous for an ENU-induced allele are mostly hairless, with only a light patch of hair around the face and tail. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acox2 |
T |
A |
14: 8,241,416 (GRCm38) |
E565D |
probably benign |
Het |
| Adam30 |
A |
T |
3: 98,162,113 (GRCm38) |
K421* |
probably null |
Het |
| Atp6v1b1 |
A |
G |
6: 83,749,852 (GRCm38) |
|
probably null |
Het |
| Cacna1a |
A |
T |
8: 84,415,930 (GRCm38) |
I96F |
possibly damaging |
Het |
| Card10 |
G |
A |
15: 78,780,514 (GRCm38) |
R747W |
probably damaging |
Het |
| Cdh8 |
T |
A |
8: 99,190,394 (GRCm38) |
D363V |
probably damaging |
Het |
| Cecr2 |
T |
C |
6: 120,757,941 (GRCm38) |
Y685H |
probably damaging |
Het |
| Cmklr1 |
T |
C |
5: 113,614,407 (GRCm38) |
T178A |
probably damaging |
Het |
| Col16a1 |
G |
A |
4: 130,092,782 (GRCm38) |
|
probably null |
Het |
| Col4a1 |
C |
T |
8: 11,226,439 (GRCm38) |
|
probably benign |
Het |
| Coro2a |
T |
A |
4: 46,548,797 (GRCm38) |
I166F |
possibly damaging |
Het |
| Cry2 |
T |
C |
2: 92,424,566 (GRCm38) |
H148R |
probably damaging |
Het |
| Crygd |
T |
C |
1: 65,061,974 (GRCm38) |
Y154C |
probably benign |
Het |
| Cubn |
T |
C |
2: 13,308,561 (GRCm38) |
Y3066C |
probably damaging |
Het |
| Defb15 |
C |
T |
8: 21,929,986 (GRCm38) |
E42K |
possibly damaging |
Het |
| Dnah12 |
A |
T |
14: 26,709,257 (GRCm38) |
Y340F |
probably benign |
Het |
| Dnah12 |
A |
G |
14: 26,697,398 (GRCm38) |
D147G |
probably benign |
Het |
| Dot1l |
G |
T |
10: 80,783,539 (GRCm38) |
R193L |
probably damaging |
Het |
| Dupd1 |
A |
G |
14: 21,686,689 (GRCm38) |
V115A |
probably benign |
Het |
| Esd |
A |
C |
14: 74,742,074 (GRCm38) |
Y119S |
probably damaging |
Het |
| Esp36 |
A |
G |
17: 38,419,439 (GRCm38) |
|
probably benign |
Het |
| Etfbkmt |
T |
A |
6: 149,144,151 (GRCm38) |
M1K |
probably null |
Het |
| Exph5 |
A |
G |
9: 53,376,248 (GRCm38) |
H1543R |
probably benign |
Het |
| Fam92a |
C |
T |
4: 12,155,717 (GRCm38) |
V306I |
possibly damaging |
Het |
| Fbxo16 |
A |
G |
14: 65,270,803 (GRCm38) |
T23A |
probably damaging |
Het |
| Gm11492 |
A |
G |
11: 87,567,235 (GRCm38) |
H145R |
possibly damaging |
Het |
| Gm6614 |
T |
C |
6: 142,003,423 (GRCm38) |
M76V |
possibly damaging |
Het |
| Gorasp2 |
C |
A |
2: 70,679,464 (GRCm38) |
H136Q |
probably damaging |
Het |
| Hdc |
T |
A |
2: 126,597,933 (GRCm38) |
I367F |
probably benign |
Het |
| Hmcn1 |
C |
T |
1: 150,638,900 (GRCm38) |
V3574M |
probably benign |
Het |
| Ilvbl |
A |
G |
10: 78,584,124 (GRCm38) |
D592G |
probably benign |
Het |
| Inmt |
G |
A |
6: 55,174,883 (GRCm38) |
A34V |
probably damaging |
Het |
| Ints9 |
A |
C |
14: 65,026,413 (GRCm38) |
H378P |
probably benign |
Het |
| Kcnh7 |
T |
A |
2: 62,787,754 (GRCm38) |
I464L |
possibly damaging |
Het |
| Kcnt2 |
T |
A |
1: 140,425,330 (GRCm38) |
V259D |
probably damaging |
Het |
| Lipo1 |
A |
G |
19: 33,784,692 (GRCm38) |
F135S |
probably damaging |
Het |
| Lrba |
T |
C |
3: 86,773,203 (GRCm38) |
|
probably null |
Het |
| Mapk1 |
T |
A |
16: 17,026,429 (GRCm38) |
S22T |
probably benign |
Het |
| Mbd3l2 |
T |
C |
9: 18,444,921 (GRCm38) |
S181P |
possibly damaging |
Het |
| Mgat5 |
C |
T |
1: 127,459,969 (GRCm38) |
P554L |
probably damaging |
Het |
| Mki67 |
T |
C |
7: 135,699,361 (GRCm38) |
T1315A |
probably benign |
Het |
| Mprip |
C |
T |
11: 59,758,221 (GRCm38) |
T917M |
possibly damaging |
Het |
| Mroh3 |
T |
A |
1: 136,185,988 (GRCm38) |
I688F |
probably benign |
Het |
| Myo1d |
A |
T |
11: 80,663,048 (GRCm38) |
Y536N |
probably damaging |
Het |
| Neb |
C |
T |
2: 52,162,187 (GRCm38) |
|
probably null |
Het |
| Noc2l |
A |
G |
4: 156,237,708 (GRCm38) |
R161G |
probably benign |
Het |
| Nup54 |
T |
A |
5: 92,419,567 (GRCm38) |
I375L |
possibly damaging |
Het |
| Nup93 |
T |
C |
8: 94,306,102 (GRCm38) |
F539L |
probably damaging |
Het |
| Olfr138 |
A |
G |
17: 38,275,344 (GRCm38) |
E191G |
probably damaging |
Het |
| Olfr417 |
T |
A |
1: 174,369,452 (GRCm38) |
H178Q |
probably damaging |
Het |
| Olfr480 |
A |
C |
7: 108,066,725 (GRCm38) |
Y24* |
probably null |
Het |
| Olfr874 |
T |
A |
9: 37,746,968 (GRCm38) |
M278K |
probably benign |
Het |
| Panx1 |
A |
T |
9: 15,007,428 (GRCm38) |
D378E |
probably damaging |
Het |
| Papss1 |
T |
A |
3: 131,583,184 (GRCm38) |
V170D |
possibly damaging |
Het |
| Pcnx |
T |
C |
12: 81,918,732 (GRCm38) |
S558P |
probably damaging |
Het |
| Pde3a |
G |
T |
6: 141,487,513 (GRCm38) |
A757S |
probably damaging |
Het |
| Pde3a |
T |
A |
6: 141,250,353 (GRCm38) |
I255N |
probably damaging |
Het |
| Pdzph1 |
A |
G |
17: 58,922,583 (GRCm38) |
Y1027H |
probably damaging |
Het |
| Pkhd1 |
G |
T |
1: 20,551,020 (GRCm38) |
R805S |
probably benign |
Het |
| Polr1a |
G |
A |
6: 71,909,203 (GRCm38) |
G14D |
probably damaging |
Het |
| Prg4 |
T |
A |
1: 150,460,669 (GRCm38) |
D60V |
probably damaging |
Het |
| Ptprc |
T |
C |
1: 138,112,227 (GRCm38) |
S311G |
probably benign |
Het |
| Rapgefl1 |
G |
A |
11: 98,842,209 (GRCm38) |
R205K |
probably benign |
Het |
| Rcan2 |
A |
T |
17: 44,037,089 (GRCm38) |
|
probably null |
Het |
| Rock1 |
A |
G |
18: 10,079,207 (GRCm38) |
I1087T |
probably damaging |
Het |
| Sectm1b |
A |
G |
11: 121,054,942 (GRCm38) |
I191T |
possibly damaging |
Het |
| Setd1b |
T |
C |
5: 123,147,613 (GRCm38) |
S241P |
unknown |
Het |
| Srpk2 |
T |
C |
5: 23,524,150 (GRCm38) |
K497R |
probably benign |
Het |
| Sspo |
T |
C |
6: 48,491,006 (GRCm38) |
S4296P |
probably damaging |
Het |
| Syne4 |
T |
C |
7: 30,316,883 (GRCm38) |
V168A |
probably benign |
Het |
| Tank |
T |
C |
2: 61,649,912 (GRCm38) |
F264S |
probably damaging |
Het |
| Trim30a |
A |
G |
7: 104,411,198 (GRCm38) |
V457A |
probably damaging |
Het |
| Trim43b |
T |
A |
9: 89,085,571 (GRCm38) |
K336N |
probably damaging |
Het |
| Trim47 |
T |
C |
11: 116,106,137 (GRCm38) |
Q598R |
probably damaging |
Het |
| Tspan12 |
T |
C |
6: 21,851,023 (GRCm38) |
N18S |
probably damaging |
Het |
| Ubap2 |
A |
G |
4: 41,221,607 (GRCm38) |
S231P |
probably benign |
Het |
| Vit |
A |
G |
17: 78,622,746 (GRCm38) |
D380G |
probably damaging |
Het |
| Vmn2r2 |
T |
C |
3: 64,134,521 (GRCm38) |
N258D |
possibly damaging |
Het |
| Vmn2r52 |
C |
T |
7: 10,173,406 (GRCm38) |
C131Y |
possibly damaging |
Het |
| Zadh2 |
T |
C |
18: 84,095,318 (GRCm38) |
V373A |
possibly damaging |
Het |
| Zfp58 |
A |
T |
13: 67,491,188 (GRCm38) |
F395I |
probably damaging |
Het |
| Zfp940 |
C |
A |
7: 29,845,010 (GRCm38) |
G491C |
probably damaging |
Het |
|
| Other mutations in Ticrr |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Ticrr
|
APN |
7 |
79,677,283 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00596:Ticrr
|
APN |
7 |
79,677,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01327:Ticrr
|
APN |
7 |
79,694,461 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01525:Ticrr
|
APN |
7 |
79,682,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01565:Ticrr
|
APN |
7 |
79,694,548 (GRCm38) |
missense |
probably benign |
|
|
IGL01936:Ticrr
|
APN |
7 |
79,694,549 (GRCm38) |
missense |
probably benign |
0.11 |
|
IGL02160:Ticrr
|
APN |
7 |
79,694,019 (GRCm38) |
missense |
probably benign |
0.29 |
|
IGL02246:Ticrr
|
APN |
7 |
79,675,328 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02487:Ticrr
|
APN |
7 |
79,683,021 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL02593:Ticrr
|
APN |
7 |
79,695,466 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02970:Ticrr
|
APN |
7 |
79,695,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
FR4304:Ticrr
|
UTSW |
7 |
79,694,311 (GRCm38) |
intron |
probably benign |
|
|
PIT4305001:Ticrr
|
UTSW |
7 |
79,679,023 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
PIT4791001:Ticrr
|
UTSW |
7 |
79,669,638 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0016:Ticrr
|
UTSW |
7 |
79,693,792 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0062:Ticrr
|
UTSW |
7 |
79,667,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0062:Ticrr
|
UTSW |
7 |
79,667,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0067:Ticrr
|
UTSW |
7 |
79,677,410 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0067:Ticrr
|
UTSW |
7 |
79,677,410 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0362:Ticrr
|
UTSW |
7 |
79,677,340 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0482:Ticrr
|
UTSW |
7 |
79,694,488 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0595:Ticrr
|
UTSW |
7 |
79,695,563 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R1118:Ticrr
|
UTSW |
7 |
79,693,953 (GRCm38) |
missense |
probably benign |
0.23 |
|
R1119:Ticrr
|
UTSW |
7 |
79,693,953 (GRCm38) |
missense |
probably benign |
0.23 |
|
R1572:Ticrr
|
UTSW |
7 |
79,681,824 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1658:Ticrr
|
UTSW |
7 |
79,695,549 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R1757:Ticrr
|
UTSW |
7 |
79,679,046 (GRCm38) |
nonsense |
probably null |
|
|
R1757:Ticrr
|
UTSW |
7 |
79,675,323 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1869:Ticrr
|
UTSW |
7 |
79,679,135 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Ticrr
|
UTSW |
7 |
79,675,394 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1966:Ticrr
|
UTSW |
7 |
79,694,735 (GRCm38) |
nonsense |
probably null |
|
|
R2006:Ticrr
|
UTSW |
7 |
79,694,073 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2178:Ticrr
|
UTSW |
7 |
79,665,685 (GRCm38) |
missense |
probably benign |
0.12 |
|
R3404:Ticrr
|
UTSW |
7 |
79,694,791 (GRCm38) |
missense |
probably benign |
0.06 |
|
R3405:Ticrr
|
UTSW |
7 |
79,694,791 (GRCm38) |
missense |
probably benign |
0.06 |
|
R3941:Ticrr
|
UTSW |
7 |
79,693,697 (GRCm38) |
intron |
probably benign |
|
|
R3950:Ticrr
|
UTSW |
7 |
79,682,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3951:Ticrr
|
UTSW |
7 |
79,682,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3952:Ticrr
|
UTSW |
7 |
79,682,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4967:Ticrr
|
UTSW |
7 |
79,660,410 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4972:Ticrr
|
UTSW |
7 |
79,669,668 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5259:Ticrr
|
UTSW |
7 |
79,694,723 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5272:Ticrr
|
UTSW |
7 |
79,669,605 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5374:Ticrr
|
UTSW |
7 |
79,690,942 (GRCm38) |
nonsense |
probably null |
|
|
R5480:Ticrr
|
UTSW |
7 |
79,660,809 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5568:Ticrr
|
UTSW |
7 |
79,695,296 (GRCm38) |
nonsense |
probably null |
|
|
R5568:Ticrr
|
UTSW |
7 |
79,689,967 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5588:Ticrr
|
UTSW |
7 |
79,679,105 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5698:Ticrr
|
UTSW |
7 |
79,679,133 (GRCm38) |
missense |
probably benign |
|
|
R5879:Ticrr
|
UTSW |
7 |
79,696,690 (GRCm38) |
missense |
probably benign |
0.12 |
|
R5980:Ticrr
|
UTSW |
7 |
79,660,955 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6128:Ticrr
|
UTSW |
7 |
79,693,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6277:Ticrr
|
UTSW |
7 |
79,694,696 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6335:Ticrr
|
UTSW |
7 |
79,694,283 (GRCm38) |
splice site |
probably null |
|
|
R6866:Ticrr
|
UTSW |
7 |
79,693,957 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6905:Ticrr
|
UTSW |
7 |
79,665,850 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6923:Ticrr
|
UTSW |
7 |
79,691,853 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6962:Ticrr
|
UTSW |
7 |
79,665,897 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R7232:Ticrr
|
UTSW |
7 |
79,693,742 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7285:Ticrr
|
UTSW |
7 |
79,660,862 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7385:Ticrr
|
UTSW |
7 |
79,691,849 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7426:Ticrr
|
UTSW |
7 |
79,693,986 (GRCm38) |
missense |
probably benign |
|
|
R7583:Ticrr
|
UTSW |
7 |
79,696,739 (GRCm38) |
nonsense |
probably null |
|
|
R7749:Ticrr
|
UTSW |
7 |
79,679,096 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7863:Ticrr
|
UTSW |
7 |
79,682,012 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7899:Ticrr
|
UTSW |
7 |
79,669,485 (GRCm38) |
missense |
probably benign |
0.23 |
|
R7935:Ticrr
|
UTSW |
7 |
79,681,836 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8005:Ticrr
|
UTSW |
7 |
79,694,048 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8080:Ticrr
|
UTSW |
7 |
79,684,264 (GRCm38) |
splice site |
probably null |
|
|
R8181:Ticrr
|
UTSW |
7 |
79,660,980 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8349:Ticrr
|
UTSW |
7 |
79,694,680 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8410:Ticrr
|
UTSW |
7 |
79,667,675 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8449:Ticrr
|
UTSW |
7 |
79,694,680 (GRCm38) |
missense |
probably benign |
0.27 |
|
R9073:Ticrr
|
UTSW |
7 |
79,667,931 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9090:Ticrr
|
UTSW |
7 |
79,660,856 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R9271:Ticrr
|
UTSW |
7 |
79,660,856 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R9287:Ticrr
|
UTSW |
7 |
79,693,768 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9368:Ticrr
|
UTSW |
7 |
79,680,987 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9469:Ticrr
|
UTSW |
7 |
79,694,763 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9502:Ticrr
|
UTSW |
7 |
79,693,849 (GRCm38) |
missense |
probably benign |
|
|
R9614:Ticrr
|
UTSW |
7 |
79,696,006 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9761:Ticrr
|
UTSW |
7 |
79,695,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9779:Ticrr
|
UTSW |
7 |
79,679,054 (GRCm38) |
missense |
probably benign |
0.37 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGAGATGCAAGCTTCTGG -3'
(R):5'- TCCAGCACTGCAATCCACTG -3'
Sequencing Primer
(F):5'- GAGATGCAAGCTTCTGGCCTTC -3'
(R):5'- ATAATTTCAGGAGTGGTCTTCCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation