Incidental Mutation 'R1817:Plxnd1'
| ID |
204488 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnd1
|
| Ensembl Gene |
ENSMUSG00000030123 |
| Gene Name |
plexin D1 |
| Synonyms |
6230425C21Rik, b2b1863Clo, b2b553Clo |
| MMRRC Submission |
039845-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1817 (G1)
|
| Quality Score |
220 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
115931772-115971966 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 115957562 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 491
(T491A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000015511
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000015511]
|
| AlphaFold |
Q3UH93 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000015511
AA Change: T491A
PolyPhen 2
Score 0.828 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000015511
Gene: ENSMUSG00000030123
AA Change: T491A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
48 |
N/A |
INTRINSIC |
|
Sema
|
61 |
531 |
6.52e-90 |
SMART |
|
PSI
|
550 |
603 |
6.06e-12 |
SMART |
|
PSI
|
703 |
755 |
1.06e-2 |
SMART |
|
Blast:PSI
|
850 |
891 |
9e-20 |
BLAST |
|
IPT
|
892 |
981 |
4.43e-20 |
SMART |
|
IPT
|
982 |
1068 |
6.61e-19 |
SMART |
|
IPT
|
1070 |
1149 |
6.13e-14 |
SMART |
|
transmembrane domain
|
1271 |
1293 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1345 |
1888 |
5e-238 |
PFAM |
|
| Meta Mutation Damage Score |
0.8981 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 91.9%
|
| Validation Efficiency |
95% (90/95) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display neonatal lethality, thin-walled atria, and vascular abnormalities including abnormal branchial arch artery development, cardiac outflow tract abnormalities, and reduced vascular smooth muscle around some vessels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
A |
T |
11: 110,110,144 (GRCm39) |
S600T |
probably benign |
Het |
| Acly |
T |
A |
11: 100,386,717 (GRCm39) |
Q615L |
probably benign |
Het |
| Adgrf1 |
C |
A |
17: 43,620,924 (GRCm39) |
T387K |
probably benign |
Het |
| Afg3l1 |
G |
T |
8: 124,228,670 (GRCm39) |
K745N |
probably damaging |
Het |
| Armc8 |
T |
C |
9: 99,418,312 (GRCm39) |
T39A |
possibly damaging |
Het |
| Atm |
C |
A |
9: 53,403,533 (GRCm39) |
|
probably benign |
Het |
| Babam2 |
A |
G |
5: 32,214,890 (GRCm39) |
T324A |
probably damaging |
Het |
| Btd |
C |
A |
14: 31,384,246 (GRCm39) |
D77E |
possibly damaging |
Het |
| Cadm1 |
T |
A |
9: 47,740,668 (GRCm39) |
|
probably benign |
Het |
| Card11 |
A |
T |
5: 140,871,315 (GRCm39) |
D729E |
probably benign |
Het |
| Ccni |
G |
T |
5: 93,335,967 (GRCm39) |
T144K |
possibly damaging |
Het |
| Ceacam23 |
C |
T |
7: 17,607,255 (GRCm39) |
|
noncoding transcript |
Het |
| Cecr2 |
A |
G |
6: 120,708,228 (GRCm39) |
T77A |
probably damaging |
Het |
| Cgas |
A |
G |
9: 78,341,593 (GRCm39) |
|
probably null |
Het |
| Cpsf7 |
T |
C |
19: 10,512,803 (GRCm39) |
F296L |
possibly damaging |
Het |
| Cyfip1 |
C |
A |
7: 55,523,196 (GRCm39) |
N70K |
possibly damaging |
Het |
| Cyp4a12b |
A |
G |
4: 115,271,259 (GRCm39) |
|
probably benign |
Het |
| Ddx20 |
A |
T |
3: 105,585,896 (GRCm39) |
Y816* |
probably null |
Het |
| Ddx59 |
A |
G |
1: 136,360,245 (GRCm39) |
I420V |
probably damaging |
Het |
| Dgat1 |
T |
A |
15: 76,386,703 (GRCm39) |
M445L |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,246,546 (GRCm39) |
L628* |
probably null |
Het |
| Dnah7a |
A |
C |
1: 53,598,307 (GRCm39) |
D1409E |
probably benign |
Het |
| Dnmt1 |
T |
C |
9: 20,838,422 (GRCm39) |
T215A |
probably benign |
Het |
| Dsg4 |
C |
T |
18: 20,604,302 (GRCm39) |
T923M |
probably damaging |
Het |
| Enox1 |
A |
G |
14: 77,852,915 (GRCm39) |
I394V |
possibly damaging |
Het |
| Esrp2 |
A |
T |
8: 106,861,250 (GRCm39) |
M183K |
probably damaging |
Het |
| Fam171a1 |
C |
T |
2: 3,179,410 (GRCm39) |
P79S |
probably benign |
Het |
| Fga |
A |
G |
3: 82,939,082 (GRCm39) |
T486A |
probably benign |
Het |
| Fkbp10 |
G |
T |
11: 100,306,715 (GRCm39) |
A36S |
probably benign |
Het |
| Fnip1 |
A |
G |
11: 54,393,279 (GRCm39) |
T572A |
probably benign |
Het |
| Fxn |
A |
C |
19: 24,257,765 (GRCm39) |
|
probably null |
Het |
| Gaa |
C |
T |
11: 119,175,324 (GRCm39) |
Q901* |
probably null |
Het |
| Gabrg1 |
A |
G |
5: 70,911,594 (GRCm39) |
M344T |
probably benign |
Het |
| Galnt7 |
C |
T |
8: 57,991,212 (GRCm39) |
V433M |
probably damaging |
Het |
| Gin1 |
A |
G |
1: 97,712,951 (GRCm39) |
|
probably null |
Het |
| Hydin |
A |
C |
8: 111,259,459 (GRCm39) |
D2477A |
probably benign |
Het |
| Igsf6 |
T |
C |
7: 120,670,031 (GRCm39) |
Y37C |
probably damaging |
Het |
| Il18rap |
A |
G |
1: 40,570,687 (GRCm39) |
I210V |
probably benign |
Het |
| Kif3a |
T |
C |
11: 53,489,561 (GRCm39) |
Y138H |
probably damaging |
Het |
| Klra17 |
A |
G |
6: 129,845,681 (GRCm39) |
|
probably null |
Het |
| Lcorl |
A |
T |
5: 45,952,688 (GRCm39) |
I55N |
probably damaging |
Het |
| Lrrc49 |
A |
G |
9: 60,510,059 (GRCm39) |
S398P |
possibly damaging |
Het |
| Ltv1 |
A |
G |
10: 13,055,018 (GRCm39) |
L384S |
probably damaging |
Het |
| Mageb3 |
A |
T |
2: 121,784,918 (GRCm39) |
Y261* |
probably null |
Het |
| Mical3 |
T |
G |
6: 121,019,196 (GRCm39) |
T9P |
probably benign |
Het |
| Myrip |
C |
T |
9: 120,217,228 (GRCm39) |
S49L |
probably damaging |
Het |
| Nrap |
T |
C |
19: 56,372,487 (GRCm39) |
|
probably benign |
Het |
| Or2m12 |
T |
C |
16: 19,104,627 (GRCm39) |
N289D |
probably damaging |
Het |
| Or4k5 |
A |
G |
14: 50,385,728 (GRCm39) |
V201A |
probably benign |
Het |
| Otoa |
A |
T |
7: 120,759,753 (GRCm39) |
|
probably benign |
Het |
| Pals2 |
T |
G |
6: 50,140,411 (GRCm39) |
F144V |
probably benign |
Het |
| Parp11 |
T |
A |
6: 127,467,008 (GRCm39) |
I133N |
probably damaging |
Het |
| Pcnx1 |
A |
G |
12: 81,965,416 (GRCm39) |
T528A |
probably benign |
Het |
| Pde4c |
A |
G |
8: 71,179,638 (GRCm39) |
H63R |
probably benign |
Het |
| Pdpk1 |
T |
C |
17: 24,329,878 (GRCm39) |
K53E |
probably damaging |
Het |
| Pdzd7 |
A |
T |
19: 45,024,615 (GRCm39) |
M468K |
probably damaging |
Het |
| Perm1 |
C |
A |
4: 156,303,061 (GRCm39) |
P535Q |
possibly damaging |
Het |
| Pgap1 |
C |
A |
1: 54,575,128 (GRCm39) |
A265S |
probably benign |
Het |
| Pik3c2a |
A |
T |
7: 115,975,747 (GRCm39) |
|
probably null |
Het |
| Pms1 |
A |
T |
1: 53,246,128 (GRCm39) |
D470E |
probably benign |
Het |
| Prf1 |
C |
A |
10: 61,138,762 (GRCm39) |
T240N |
probably damaging |
Het |
| Prune2 |
A |
G |
19: 17,099,445 (GRCm39) |
T1650A |
probably benign |
Het |
| Ptprf |
A |
G |
4: 118,080,462 (GRCm39) |
L1264P |
probably benign |
Het |
| Ptprs |
A |
G |
17: 56,726,527 (GRCm39) |
S948P |
probably damaging |
Het |
| Rapgef1 |
T |
C |
2: 29,576,268 (GRCm39) |
V117A |
probably damaging |
Het |
| Rnf123 |
A |
G |
9: 107,940,125 (GRCm39) |
V756A |
probably benign |
Het |
| Sez6l2 |
A |
G |
7: 126,566,291 (GRCm39) |
E741G |
probably damaging |
Het |
| Shc3 |
A |
T |
13: 51,626,888 (GRCm39) |
I125K |
possibly damaging |
Het |
| Smr3a |
A |
T |
5: 88,155,917 (GRCm39) |
|
probably benign |
Het |
| Spef2 |
C |
T |
15: 9,584,194 (GRCm39) |
E1624K |
probably damaging |
Het |
| St6gal1 |
A |
T |
16: 23,140,083 (GRCm39) |
K85* |
probably null |
Het |
| Taf1b |
T |
G |
12: 24,597,121 (GRCm39) |
D353E |
possibly damaging |
Het |
| Tcp10b |
C |
T |
17: 13,286,590 (GRCm39) |
P180S |
possibly damaging |
Het |
| Tlr9 |
A |
T |
9: 106,102,142 (GRCm39) |
M478L |
probably benign |
Het |
| Tpr |
A |
T |
1: 150,295,654 (GRCm39) |
E892D |
probably damaging |
Het |
| Trio |
C |
T |
15: 27,742,581 (GRCm39) |
W22* |
probably null |
Het |
| Usp14 |
A |
G |
18: 10,024,673 (GRCm39) |
V8A |
probably damaging |
Het |
| Vmn2r19 |
A |
T |
6: 123,307,011 (GRCm39) |
K506N |
possibly damaging |
Het |
| Vmn2r45 |
T |
A |
7: 8,475,372 (GRCm39) |
N552I |
probably damaging |
Het |
| Vmn2r56 |
A |
T |
7: 12,449,542 (GRCm39) |
M232K |
probably benign |
Het |
| Vps13b |
T |
A |
15: 35,910,788 (GRCm39) |
F3517L |
possibly damaging |
Het |
| Yif1a |
C |
T |
19: 5,142,333 (GRCm39) |
R247* |
probably null |
Het |
| Zbtb5 |
A |
G |
4: 44,993,767 (GRCm39) |
V539A |
probably benign |
Het |
| Zfp180 |
G |
A |
7: 23,804,652 (GRCm39) |
R357Q |
probably damaging |
Het |
| Zfp536 |
A |
G |
7: 37,268,042 (GRCm39) |
L458P |
probably damaging |
Het |
| Zfp646 |
G |
A |
7: 127,482,292 (GRCm39) |
G1490S |
probably benign |
Het |
| Zfp970 |
C |
T |
2: 177,167,976 (GRCm39) |
H517Y |
probably damaging |
Het |
| Zranb3 |
A |
T |
1: 127,945,293 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Plxnd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00764:Plxnd1
|
APN |
6 |
115,944,933 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01099:Plxnd1
|
APN |
6 |
115,946,906 (GRCm39) |
missense |
probably benign |
|
|
IGL01323:Plxnd1
|
APN |
6 |
115,943,760 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01382:Plxnd1
|
APN |
6 |
115,937,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Plxnd1
|
APN |
6 |
115,936,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02244:Plxnd1
|
APN |
6 |
115,955,218 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02272:Plxnd1
|
APN |
6 |
115,970,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02293:Plxnd1
|
APN |
6 |
115,940,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02465:Plxnd1
|
APN |
6 |
115,932,703 (GRCm39) |
makesense |
probably null |
|
|
IGL02873:Plxnd1
|
APN |
6 |
115,936,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03209:Plxnd1
|
APN |
6 |
115,939,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Hiss
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
murmer
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
mutter
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
rattle
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0238:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0239:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0357:Plxnd1
|
UTSW |
6 |
115,946,421 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0646:Plxnd1
|
UTSW |
6 |
115,935,660 (GRCm39) |
splice site |
probably benign |
|
|
R0648:Plxnd1
|
UTSW |
6 |
115,970,962 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0718:Plxnd1
|
UTSW |
6 |
115,943,599 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1116:Plxnd1
|
UTSW |
6 |
115,943,966 (GRCm39) |
splice site |
probably null |
|
|
R1292:Plxnd1
|
UTSW |
6 |
115,939,644 (GRCm39) |
unclassified |
probably benign |
|
|
R1715:Plxnd1
|
UTSW |
6 |
115,945,642 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1760:Plxnd1
|
UTSW |
6 |
115,944,740 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1799:Plxnd1
|
UTSW |
6 |
115,971,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1848:Plxnd1
|
UTSW |
6 |
115,943,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1851:Plxnd1
|
UTSW |
6 |
115,940,875 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1865:Plxnd1
|
UTSW |
6 |
115,946,402 (GRCm39) |
splice site |
probably null |
|
|
R1875:Plxnd1
|
UTSW |
6 |
115,955,045 (GRCm39) |
splice site |
probably null |
|
|
R1899:Plxnd1
|
UTSW |
6 |
115,946,324 (GRCm39) |
missense |
probably benign |
|
|
R1913:Plxnd1
|
UTSW |
6 |
115,954,978 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1970:Plxnd1
|
UTSW |
6 |
115,939,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2007:Plxnd1
|
UTSW |
6 |
115,944,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2134:Plxnd1
|
UTSW |
6 |
115,934,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Plxnd1
|
UTSW |
6 |
115,939,725 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2230:Plxnd1
|
UTSW |
6 |
115,941,105 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2267:Plxnd1
|
UTSW |
6 |
115,939,704 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2427:Plxnd1
|
UTSW |
6 |
115,944,709 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4108:Plxnd1
|
UTSW |
6 |
115,936,276 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4233:Plxnd1
|
UTSW |
6 |
115,942,914 (GRCm39) |
missense |
probably benign |
0.30 |
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,056 (GRCm39) |
splice site |
probably null |
|
|
R4280:Plxnd1
|
UTSW |
6 |
115,933,055 (GRCm39) |
splice site |
probably benign |
|
|
R4346:Plxnd1
|
UTSW |
6 |
115,954,941 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4439:Plxnd1
|
UTSW |
6 |
115,970,937 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4572:Plxnd1
|
UTSW |
6 |
115,932,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4576:Plxnd1
|
UTSW |
6 |
115,945,005 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4599:Plxnd1
|
UTSW |
6 |
115,971,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4614:Plxnd1
|
UTSW |
6 |
115,949,486 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4700:Plxnd1
|
UTSW |
6 |
115,935,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4705:Plxnd1
|
UTSW |
6 |
115,935,581 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4806:Plxnd1
|
UTSW |
6 |
115,937,816 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Plxnd1
|
UTSW |
6 |
115,932,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4977:Plxnd1
|
UTSW |
6 |
115,971,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5069:Plxnd1
|
UTSW |
6 |
115,942,862 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5155:Plxnd1
|
UTSW |
6 |
115,935,949 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5460:Plxnd1
|
UTSW |
6 |
115,934,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5729:Plxnd1
|
UTSW |
6 |
115,942,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Plxnd1
|
UTSW |
6 |
115,945,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5992:Plxnd1
|
UTSW |
6 |
115,944,748 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6129:Plxnd1
|
UTSW |
6 |
115,955,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6254:Plxnd1
|
UTSW |
6 |
115,954,921 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6273:Plxnd1
|
UTSW |
6 |
115,955,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Plxnd1
|
UTSW |
6 |
115,953,697 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6732:Plxnd1
|
UTSW |
6 |
115,946,890 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6857:Plxnd1
|
UTSW |
6 |
115,970,724 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7243:Plxnd1
|
UTSW |
6 |
115,949,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7282:Plxnd1
|
UTSW |
6 |
115,937,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7632:Plxnd1
|
UTSW |
6 |
115,953,600 (GRCm39) |
missense |
probably benign |
|
|
R7699:Plxnd1
|
UTSW |
6 |
115,936,755 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7915:Plxnd1
|
UTSW |
6 |
115,943,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8090:Plxnd1
|
UTSW |
6 |
115,933,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8382:Plxnd1
|
UTSW |
6 |
115,949,433 (GRCm39) |
missense |
probably benign |
|
|
R8507:Plxnd1
|
UTSW |
6 |
115,943,866 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8539:Plxnd1
|
UTSW |
6 |
115,939,768 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8548:Plxnd1
|
UTSW |
6 |
115,934,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8963:Plxnd1
|
UTSW |
6 |
115,949,506 (GRCm39) |
nonsense |
probably null |
|
|
R9119:Plxnd1
|
UTSW |
6 |
115,932,832 (GRCm39) |
splice site |
probably benign |
|
|
R9177:Plxnd1
|
UTSW |
6 |
115,943,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9182:Plxnd1
|
UTSW |
6 |
115,970,746 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9185:Plxnd1
|
UTSW |
6 |
115,934,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9226:Plxnd1
|
UTSW |
6 |
115,934,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9433:Plxnd1
|
UTSW |
6 |
115,945,754 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9449:Plxnd1
|
UTSW |
6 |
115,932,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9451:Plxnd1
|
UTSW |
6 |
115,940,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R9599:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9627:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9644:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9672:Plxnd1
|
UTSW |
6 |
115,940,274 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
X0024:Plxnd1
|
UTSW |
6 |
115,940,271 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0026:Plxnd1
|
UTSW |
6 |
115,943,745 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
Z1088:Plxnd1
|
UTSW |
6 |
115,944,471 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTGCAAAGGTCAAGATGCG -3'
(R):5'- AGAGCTGAGTCTAACCTGCC -3'
Sequencing Primer
(F):5'- CCCAGGCTAGGAGATGCTG -3'
(R):5'- CTGTCTTCACAGCTGCAGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation