Incidental Mutation 'R1818:Ephb2'
| ID |
204583 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ephb2
|
| Ensembl Gene |
ENSMUSG00000028664 |
| Gene Name |
Eph receptor B2 |
| Synonyms |
eteck, Cek5, Qek5, Sek3, Hek5, Drt, Prkm5, Nuk, Erk, Tyro5 |
| MMRRC Submission |
039846-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.740)
|
| Stock # |
R1818 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
136374850-136563299 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 136382647 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 984
(S984P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101472
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000059287]
[ENSMUST00000105845]
[ENSMUST00000105846]
|
| AlphaFold |
P54763 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000059287
AA Change: S984P
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000058135
Gene: ENSMUSG00000028664
AA Change: S984P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
EPH_lbd
|
20 |
197 |
7.37e-130 |
SMART |
|
Pfam:GCC2_GCC3
|
261 |
304 |
8.1e-10 |
PFAM |
|
FN3
|
325 |
417 |
1.75e-6 |
SMART |
|
FN3
|
436 |
518 |
1.23e-10 |
SMART |
|
Pfam:EphA2_TM
|
545 |
619 |
6e-25 |
PFAM |
|
TyrKc
|
622 |
881 |
1.34e-138 |
SMART |
|
SAM
|
911 |
978 |
1.18e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105845
AA Change: S983P
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| SMART Domains |
Protein: ENSMUSP00000101471
Gene: ENSMUSG00000028664
AA Change: S983P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
EPH_lbd
|
20 |
197 |
7.37e-130 |
SMART |
|
Pfam:GCC2_GCC3
|
259 |
305 |
2.2e-10 |
PFAM |
|
FN3
|
325 |
417 |
1.75e-6 |
SMART |
|
FN3
|
436 |
517 |
1.41e-10 |
SMART |
|
Pfam:EphA2_TM
|
543 |
618 |
2.1e-30 |
PFAM |
|
TyrKc
|
621 |
880 |
1.34e-138 |
SMART |
|
SAM
|
910 |
977 |
1.18e-23 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000105846
AA Change: S984P
PolyPhen 2
Score 0.017 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000101472
Gene: ENSMUSG00000028664
AA Change: S984P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
EPH_lbd
|
20 |
197 |
7.37e-130 |
SMART |
|
Pfam:GCC2_GCC3
|
259 |
305 |
2.2e-10 |
PFAM |
|
FN3
|
325 |
417 |
1.75e-6 |
SMART |
|
FN3
|
436 |
517 |
1.41e-10 |
SMART |
|
Pfam:EphA2_TM
|
543 |
619 |
1e-30 |
PFAM |
|
TyrKc
|
622 |
881 |
1.34e-138 |
SMART |
|
SAM
|
911 |
978 |
1.18e-23 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151502
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.6%
- 10x: 94.5%
- 20x: 90.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors consist of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. The encoded receptor preferentially binds membrane-bound ephrin-B ligands and is involved in nervous system and vascular development. This gene is used as a marker of intestinal stem cells. Homozygous knockout mice for this gene exhibit impaired axon guidance and vestibular function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
PHENOTYPE: Mice homozygous for a null allele exhibit abnormal axon guidance, circling, head bobbing, and hyperactivity. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aass |
T |
A |
6: 23,075,857 (GRCm39) |
|
probably null |
Het |
| Adam6b |
T |
A |
12: 113,454,876 (GRCm39) |
N564K |
probably benign |
Het |
| Ahi1 |
A |
G |
10: 20,864,461 (GRCm39) |
Y731C |
probably damaging |
Het |
| Ankk1 |
A |
G |
9: 49,331,725 (GRCm39) |
Y190H |
probably benign |
Het |
| Ankmy1 |
T |
A |
1: 92,814,553 (GRCm39) |
D318V |
probably benign |
Het |
| Ankrd33b |
G |
A |
15: 31,367,267 (GRCm39) |
A91V |
probably damaging |
Het |
| Ap3b1 |
A |
G |
13: 94,608,212 (GRCm39) |
N561S |
possibly damaging |
Het |
| Apob |
A |
G |
12: 8,056,834 (GRCm39) |
N1739S |
probably damaging |
Het |
| Apob |
A |
G |
12: 8,063,064 (GRCm39) |
T236A |
possibly damaging |
Het |
| Birc6 |
G |
A |
17: 74,956,844 (GRCm39) |
A3593T |
probably damaging |
Het |
| Bnc2 |
A |
G |
4: 84,210,111 (GRCm39) |
F778L |
possibly damaging |
Het |
| Capn2 |
T |
A |
1: 182,300,162 (GRCm39) |
K609N |
probably benign |
Het |
| Car9 |
G |
T |
4: 43,512,439 (GRCm39) |
|
probably null |
Het |
| Card11 |
A |
T |
5: 140,871,315 (GRCm39) |
D729E |
probably benign |
Het |
| Ccl20 |
A |
G |
1: 83,095,529 (GRCm39) |
Y30C |
probably damaging |
Het |
| Cd209a |
G |
A |
8: 3,795,576 (GRCm39) |
T106I |
probably damaging |
Het |
| Cebpz |
A |
G |
17: 79,242,805 (GRCm39) |
L283P |
probably damaging |
Het |
| Cecr2 |
A |
G |
6: 120,708,228 (GRCm39) |
T77A |
probably damaging |
Het |
| Clec4e |
T |
A |
6: 123,262,452 (GRCm39) |
D155V |
possibly damaging |
Het |
| Col25a1 |
G |
A |
3: 130,379,386 (GRCm39) |
|
probably null |
Het |
| Cyp2j11 |
A |
T |
4: 96,185,976 (GRCm39) |
V403D |
probably damaging |
Het |
| Cyp4v3 |
G |
A |
8: 45,768,673 (GRCm39) |
R296C |
possibly damaging |
Het |
| Ddx59 |
A |
G |
1: 136,360,245 (GRCm39) |
I420V |
probably damaging |
Het |
| Denr |
T |
A |
5: 124,055,283 (GRCm39) |
D49E |
probably benign |
Het |
| Dnaaf3 |
A |
T |
7: 4,526,568 (GRCm39) |
|
probably null |
Het |
| Dnaaf3 |
G |
T |
7: 4,526,569 (GRCm39) |
L503M |
probably benign |
Het |
| Dnah7a |
A |
C |
1: 53,598,307 (GRCm39) |
D1409E |
probably benign |
Het |
| Dnai4 |
A |
G |
4: 102,929,854 (GRCm39) |
V56A |
possibly damaging |
Het |
| Efcab3 |
T |
A |
11: 104,612,333 (GRCm39) |
L652Q |
probably benign |
Het |
| Ehd4 |
C |
T |
2: 119,932,885 (GRCm39) |
W180* |
probably null |
Het |
| Eva1a |
T |
C |
6: 82,048,125 (GRCm39) |
M1T |
probably null |
Het |
| Fam90a1a |
C |
G |
8: 22,453,787 (GRCm39) |
P381A |
possibly damaging |
Het |
| Fam90a1a |
C |
A |
8: 22,453,788 (GRCm39) |
P381Q |
probably damaging |
Het |
| Flnc |
T |
C |
6: 29,457,447 (GRCm39) |
Y2382H |
probably damaging |
Het |
| Flrt1 |
A |
T |
19: 7,072,711 (GRCm39) |
L612Q |
probably damaging |
Het |
| Fubp1 |
T |
A |
3: 151,927,806 (GRCm39) |
N419K |
probably damaging |
Het |
| Gin1 |
A |
G |
1: 97,712,951 (GRCm39) |
|
probably null |
Het |
| Gm4847 |
T |
A |
1: 166,465,788 (GRCm39) |
H267L |
probably damaging |
Het |
| Golga4 |
T |
G |
9: 118,402,055 (GRCm39) |
V91G |
probably damaging |
Het |
| Hip1r |
T |
C |
5: 124,134,018 (GRCm39) |
|
probably null |
Het |
| Ice2 |
A |
G |
9: 69,339,383 (GRCm39) |
S967G |
probably benign |
Het |
| Il18rap |
A |
G |
1: 40,570,687 (GRCm39) |
I210V |
probably benign |
Het |
| Impdh2 |
T |
G |
9: 108,440,411 (GRCm39) |
|
probably null |
Het |
| Inmt |
C |
A |
6: 55,150,404 (GRCm39) |
V78F |
possibly damaging |
Het |
| Inpp5e |
T |
C |
2: 26,287,886 (GRCm39) |
S637G |
probably benign |
Het |
| Kansl1 |
T |
C |
11: 104,233,283 (GRCm39) |
H748R |
possibly damaging |
Het |
| Kif28 |
T |
C |
1: 179,533,319 (GRCm39) |
K541E |
possibly damaging |
Het |
| Kifc1 |
G |
A |
17: 34,103,685 (GRCm39) |
R195C |
probably benign |
Het |
| Kifc2 |
T |
C |
15: 76,550,281 (GRCm39) |
V480A |
probably damaging |
Het |
| Lrrc74a |
T |
C |
12: 86,784,484 (GRCm39) |
Y71H |
probably damaging |
Het |
| Ly75 |
T |
G |
2: 60,142,121 (GRCm39) |
T1330P |
probably damaging |
Het |
| Macf1 |
A |
G |
4: 123,270,210 (GRCm39) |
V6647A |
probably damaging |
Het |
| Mgat1 |
T |
C |
11: 49,152,111 (GRCm39) |
I198T |
possibly damaging |
Het |
| Morc3 |
A |
G |
16: 93,652,398 (GRCm39) |
Y367C |
probably damaging |
Het |
| Mtfr1 |
A |
G |
3: 19,269,837 (GRCm39) |
T162A |
probably damaging |
Het |
| Myrip |
C |
T |
9: 120,217,228 (GRCm39) |
S49L |
probably damaging |
Het |
| Nup153 |
A |
T |
13: 46,835,113 (GRCm39) |
N1397K |
possibly damaging |
Het |
| Or5h26 |
T |
C |
16: 58,988,243 (GRCm39) |
K88E |
probably benign |
Het |
| Or6x1 |
T |
C |
9: 40,098,558 (GRCm39) |
V49A |
probably benign |
Het |
| Or8b36 |
T |
C |
9: 37,937,803 (GRCm39) |
S234P |
probably damaging |
Het |
| Or8g21 |
T |
C |
9: 38,905,902 (GRCm39) |
I276M |
possibly damaging |
Het |
| Pabpc2 |
G |
T |
18: 39,907,163 (GRCm39) |
V143L |
probably damaging |
Het |
| Pals2 |
T |
G |
6: 50,140,411 (GRCm39) |
F144V |
probably benign |
Het |
| Panx3 |
T |
C |
9: 37,575,322 (GRCm39) |
K180R |
probably benign |
Het |
| Patj |
G |
A |
4: 98,511,885 (GRCm39) |
V144M |
possibly damaging |
Het |
| Pde1c |
T |
A |
6: 56,103,877 (GRCm39) |
K651* |
probably null |
Het |
| Pde4c |
A |
G |
8: 71,179,638 (GRCm39) |
H63R |
probably benign |
Het |
| Pdha2 |
T |
A |
3: 140,916,960 (GRCm39) |
K183* |
probably null |
Het |
| Pkd1l3 |
T |
A |
8: 110,375,038 (GRCm39) |
C1504S |
probably benign |
Het |
| Plbd2 |
A |
T |
5: 120,625,574 (GRCm39) |
|
probably null |
Het |
| Poteg |
G |
A |
8: 27,940,195 (GRCm39) |
W121* |
probably null |
Het |
| Prf1 |
C |
A |
10: 61,138,762 (GRCm39) |
T240N |
probably damaging |
Het |
| Ptprf |
A |
G |
4: 118,067,068 (GRCm39) |
Y1883H |
probably damaging |
Het |
| Puf60 |
T |
C |
15: 75,943,323 (GRCm39) |
T322A |
possibly damaging |
Het |
| Rev3l |
A |
G |
10: 39,704,420 (GRCm39) |
I281M |
probably benign |
Het |
| Rufy1 |
T |
C |
11: 50,305,399 (GRCm39) |
I305V |
probably benign |
Het |
| Shisa9 |
A |
C |
16: 12,085,426 (GRCm39) |
Q329P |
probably damaging |
Het |
| Siglech |
G |
A |
7: 55,418,332 (GRCm39) |
R100Q |
probably damaging |
Het |
| Slc13a5 |
T |
A |
11: 72,144,169 (GRCm39) |
Y303F |
probably benign |
Het |
| Snx6 |
C |
T |
12: 54,830,259 (GRCm39) |
V67I |
possibly damaging |
Het |
| Spef2 |
C |
T |
15: 9,584,194 (GRCm39) |
E1624K |
probably damaging |
Het |
| Tecpr2 |
A |
G |
12: 110,892,888 (GRCm39) |
Y310C |
probably damaging |
Het |
| Top1 |
T |
A |
2: 160,557,643 (GRCm39) |
L575Q |
probably damaging |
Het |
| Usp16 |
C |
T |
16: 87,276,020 (GRCm39) |
R452* |
probably null |
Het |
| Utrn |
A |
G |
10: 12,585,708 (GRCm39) |
|
probably null |
Het |
| Vps13b |
G |
A |
15: 35,877,723 (GRCm39) |
G2899E |
probably benign |
Het |
| Wipi2 |
T |
A |
5: 142,643,963 (GRCm39) |
L115Q |
probably damaging |
Het |
| Zbtb7c |
A |
C |
18: 76,270,596 (GRCm39) |
E228A |
probably damaging |
Het |
| Zfp26 |
T |
C |
9: 20,353,487 (GRCm39) |
T101A |
probably benign |
Het |
| Zfp593 |
A |
T |
4: 133,972,394 (GRCm39) |
|
probably null |
Het |
| Zfp646 |
G |
A |
7: 127,482,292 (GRCm39) |
G1490S |
probably benign |
Het |
| Zfp948 |
G |
A |
17: 21,805,069 (GRCm39) |
V20M |
probably damaging |
Het |
| Zranb3 |
A |
T |
1: 127,945,293 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Ephb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00336:Ephb2
|
APN |
4 |
136,384,795 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00963:Ephb2
|
APN |
4 |
136,386,262 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01111:Ephb2
|
APN |
4 |
136,384,721 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01462:Ephb2
|
APN |
4 |
136,498,681 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL01863:Ephb2
|
APN |
4 |
136,387,088 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02149:Ephb2
|
APN |
4 |
136,421,225 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02232:Ephb2
|
APN |
4 |
136,384,762 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02269:Ephb2
|
APN |
4 |
136,498,360 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02828:Ephb2
|
APN |
4 |
136,498,461 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL03109:Ephb2
|
APN |
4 |
136,498,855 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03284:Ephb2
|
APN |
4 |
136,388,827 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Zimbalist
|
UTSW |
4 |
136,387,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB006:Ephb2
|
UTSW |
4 |
136,388,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB016:Ephb2
|
UTSW |
4 |
136,388,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4453001:Ephb2
|
UTSW |
4 |
136,388,121 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0004:Ephb2
|
UTSW |
4 |
136,384,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0121:Ephb2
|
UTSW |
4 |
136,498,368 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0539:Ephb2
|
UTSW |
4 |
136,383,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Ephb2
|
UTSW |
4 |
136,400,676 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0988:Ephb2
|
UTSW |
4 |
136,387,019 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R1471:Ephb2
|
UTSW |
4 |
136,386,262 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1473:Ephb2
|
UTSW |
4 |
136,421,369 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1546:Ephb2
|
UTSW |
4 |
136,498,320 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1639:Ephb2
|
UTSW |
4 |
136,421,216 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1725:Ephb2
|
UTSW |
4 |
136,387,089 (GRCm39) |
nonsense |
probably null |
|
|
R1779:Ephb2
|
UTSW |
4 |
136,421,136 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R2099:Ephb2
|
UTSW |
4 |
136,388,066 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2916:Ephb2
|
UTSW |
4 |
136,411,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3885:Ephb2
|
UTSW |
4 |
136,498,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4572:Ephb2
|
UTSW |
4 |
136,383,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4709:Ephb2
|
UTSW |
4 |
136,423,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4893:Ephb2
|
UTSW |
4 |
136,387,064 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4981:Ephb2
|
UTSW |
4 |
136,423,321 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4992:Ephb2
|
UTSW |
4 |
136,388,150 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5004:Ephb2
|
UTSW |
4 |
136,387,010 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5307:Ephb2
|
UTSW |
4 |
136,421,098 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5370:Ephb2
|
UTSW |
4 |
136,498,881 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5561:Ephb2
|
UTSW |
4 |
136,388,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5643:Ephb2
|
UTSW |
4 |
136,498,923 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5826:Ephb2
|
UTSW |
4 |
136,388,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5858:Ephb2
|
UTSW |
4 |
136,399,756 (GRCm39) |
missense |
probably benign |
|
|
R5867:Ephb2
|
UTSW |
4 |
136,402,733 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5990:Ephb2
|
UTSW |
4 |
136,423,366 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6000:Ephb2
|
UTSW |
4 |
136,411,341 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6156:Ephb2
|
UTSW |
4 |
136,388,816 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6413:Ephb2
|
UTSW |
4 |
136,498,433 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6577:Ephb2
|
UTSW |
4 |
136,384,861 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6633:Ephb2
|
UTSW |
4 |
136,411,307 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6720:Ephb2
|
UTSW |
4 |
136,384,813 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6795:Ephb2
|
UTSW |
4 |
136,400,646 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7235:Ephb2
|
UTSW |
4 |
136,421,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7260:Ephb2
|
UTSW |
4 |
136,498,885 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7328:Ephb2
|
UTSW |
4 |
136,386,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7404:Ephb2
|
UTSW |
4 |
136,498,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7466:Ephb2
|
UTSW |
4 |
136,386,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7524:Ephb2
|
UTSW |
4 |
136,387,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7605:Ephb2
|
UTSW |
4 |
136,498,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7611:Ephb2
|
UTSW |
4 |
136,388,212 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7777:Ephb2
|
UTSW |
4 |
136,498,947 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7889:Ephb2
|
UTSW |
4 |
136,498,353 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7929:Ephb2
|
UTSW |
4 |
136,388,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8191:Ephb2
|
UTSW |
4 |
136,386,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8370:Ephb2
|
UTSW |
4 |
136,383,302 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8444:Ephb2
|
UTSW |
4 |
136,388,711 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Ephb2
|
UTSW |
4 |
136,498,368 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8988:Ephb2
|
UTSW |
4 |
136,402,769 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9410:Ephb2
|
UTSW |
4 |
136,386,948 (GRCm39) |
missense |
probably null |
1.00 |
|
R9722:Ephb2
|
UTSW |
4 |
136,384,768 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCCTTTGACTTGCATGGGC -3'
(R):5'- TTTGACACCCAATGCCCATC -3'
Sequencing Primer
(F):5'- CCTTTGACTTGCATGGGCTCTTG -3'
(R):5'- TCTCCCAAAGGGACATTC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation