Incidental Mutation 'R1833:Magi2'
| ID |
204935 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Magi2
|
| Ensembl Gene |
ENSMUSG00000040003 |
| Gene Name |
membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| Synonyms |
Acvrinp1, Magi-2, S-SCAM |
| MMRRC Submission |
039860-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1833 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
19432034-20909790 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 19432455 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Cysteine
at position 57
(G57C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142764
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000088516]
[ENSMUST00000197354]
[ENSMUST00000197443]
|
| AlphaFold |
Q9WVQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000088516
AA Change: G57C
PolyPhen 2
Score 0.069 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000085872
Gene: ENSMUSG00000040003
AA Change: G57C
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
5.26e-9 |
SMART |
|
GuKc
|
107 |
290 |
2.76e-45 |
SMART |
|
WW
|
302 |
334 |
7.43e-12 |
SMART |
|
WW
|
348 |
380 |
2.4e-6 |
SMART |
|
PDZ
|
433 |
509 |
3.51e-19 |
SMART |
|
PDZ
|
612 |
682 |
2.3e-14 |
SMART |
|
PDZ
|
785 |
861 |
4.04e-19 |
SMART |
|
low complexity region
|
893 |
907 |
N/A |
INTRINSIC |
|
PDZ
|
928 |
1009 |
5.05e-20 |
SMART |
|
low complexity region
|
1052 |
1063 |
N/A |
INTRINSIC |
|
PDZ
|
1147 |
1221 |
3.88e-21 |
SMART |
|
low complexity region
|
1257 |
1270 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180594
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000197354
AA Change: G57C
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000142576
Gene: ENSMUSG00000040003
AA Change: G57C
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
2.5e-11 |
SMART |
|
GuKc
|
107 |
290 |
1.4e-47 |
SMART |
|
WW
|
302 |
334 |
4.3e-14 |
SMART |
|
WW
|
348 |
380 |
1.4e-8 |
SMART |
|
PDZ
|
433 |
509 |
1.7e-21 |
SMART |
|
PDZ
|
612 |
682 |
1.1e-16 |
SMART |
|
PDZ
|
785 |
861 |
2e-21 |
SMART |
|
low complexity region
|
893 |
907 |
N/A |
INTRINSIC |
|
PDZ
|
928 |
1009 |
2.4e-22 |
SMART |
|
low complexity region
|
1052 |
1063 |
N/A |
INTRINSIC |
|
PDZ
|
1147 |
1221 |
1.9e-23 |
SMART |
|
low complexity region
|
1255 |
1269 |
N/A |
INTRINSIC |
|
low complexity region
|
1304 |
1319 |
N/A |
INTRINSIC |
|
low complexity region
|
1344 |
1363 |
N/A |
INTRINSIC |
|
low complexity region
|
1368 |
1384 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000197443
AA Change: G57C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142764
Gene: ENSMUSG00000040003
AA Change: G57C
| Domain | Start | End | E-Value | Type |
|---|
|
PDZ
|
26 |
101 |
2.5e-11 |
SMART |
|
GuKc
|
107 |
290 |
1.4e-47 |
SMART |
|
WW
|
302 |
334 |
4.3e-14 |
SMART |
|
WW
|
348 |
380 |
1.4e-8 |
SMART |
|
PDZ
|
433 |
509 |
1.7e-21 |
SMART |
|
PDZ
|
612 |
682 |
1.1e-16 |
SMART |
|
PDZ
|
771 |
847 |
2e-21 |
SMART |
|
low complexity region
|
879 |
893 |
N/A |
INTRINSIC |
|
PDZ
|
914 |
995 |
2.4e-22 |
SMART |
|
low complexity region
|
1038 |
1049 |
N/A |
INTRINSIC |
|
PDZ
|
1133 |
1207 |
1.9e-23 |
SMART |
|
low complexity region
|
1241 |
1255 |
N/A |
INTRINSIC |
|
low complexity region
|
1290 |
1305 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1354 |
1370 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197496
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199384
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200518
|
| Meta Mutation Damage Score |
0.4015 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.9%
|
| Validation Efficiency |
99% (83/84) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene interacts with atrophin-1. Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. This encoded protein is characterized by two WW domains, a guanylate kinase-like domain, and multiple PDZ domains. It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a null allele show neonatal death and hippocampal neurons with altered dendritic spine morphology. Homozygotes for a different null allele die neonatally due to anuria and podocyte anomalies. Mice lacking all three isoforms develop proteinuria, podocytopathy and die of renal failure. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700003H04Rik |
T |
A |
3: 124,350,509 (GRCm39) |
D143V |
unknown |
Het |
| 4930438A08Rik |
C |
T |
11: 58,179,214 (GRCm39) |
Q183* |
probably null |
Het |
| 9230009I02Rik |
A |
G |
11: 50,982,293 (GRCm39) |
|
noncoding transcript |
Het |
| Abhd12 |
T |
A |
2: 150,690,338 (GRCm39) |
D119V |
probably damaging |
Het |
| Adam1b |
A |
G |
5: 121,641,000 (GRCm39) |
I15T |
possibly damaging |
Het |
| Agtpbp1 |
A |
T |
13: 59,613,797 (GRCm39) |
|
probably null |
Het |
| Arfgef1 |
G |
C |
1: 10,275,115 (GRCm39) |
I312M |
probably benign |
Het |
| Arid4a |
C |
T |
12: 71,122,240 (GRCm39) |
L874F |
possibly damaging |
Het |
| Bcas3 |
G |
A |
11: 85,474,775 (GRCm39) |
V317I |
probably benign |
Het |
| Ccr1 |
T |
A |
9: 123,764,126 (GRCm39) |
I135F |
probably damaging |
Het |
| Ces2h |
A |
G |
8: 105,747,005 (GRCm39) |
E547G |
possibly damaging |
Het |
| Ces3b |
T |
A |
8: 105,812,271 (GRCm39) |
D173E |
probably damaging |
Het |
| Chd3 |
A |
G |
11: 69,244,949 (GRCm39) |
L1197S |
probably damaging |
Het |
| Cngb1 |
A |
G |
8: 95,968,983 (GRCm39) |
L1175P |
probably damaging |
Het |
| Cyp4f17 |
T |
C |
17: 32,743,184 (GRCm39) |
F286L |
probably benign |
Het |
| Dclre1a |
C |
T |
19: 56,529,932 (GRCm39) |
|
probably null |
Het |
| Dennd6a |
T |
A |
14: 26,328,109 (GRCm39) |
L44H |
probably damaging |
Het |
| Dhx16 |
A |
G |
17: 36,196,511 (GRCm39) |
T560A |
probably benign |
Het |
| Dusp12 |
T |
C |
1: 170,702,022 (GRCm39) |
M326V |
probably benign |
Het |
| Eif3k |
T |
C |
7: 28,670,852 (GRCm39) |
I180V |
probably benign |
Het |
| Erc1 |
A |
G |
6: 119,720,390 (GRCm39) |
I437T |
possibly damaging |
Het |
| Farp2 |
T |
A |
1: 93,504,086 (GRCm39) |
|
probably benign |
Het |
| Foxa3 |
A |
G |
7: 18,748,499 (GRCm39) |
L209P |
probably damaging |
Het |
| Garin2 |
G |
A |
12: 78,762,280 (GRCm39) |
|
probably benign |
Het |
| Gen1 |
A |
T |
12: 11,298,352 (GRCm39) |
|
probably benign |
Het |
| Gm10305 |
A |
G |
4: 99,161,363 (GRCm39) |
T91A |
unknown |
Het |
| Gm14412 |
T |
C |
2: 177,007,583 (GRCm39) |
D104G |
probably benign |
Het |
| Gm6900 |
T |
C |
7: 10,390,515 (GRCm39) |
|
noncoding transcript |
Het |
| Gpx1 |
A |
T |
9: 108,216,555 (GRCm39) |
Y15F |
possibly damaging |
Het |
| H2-M10.3 |
T |
C |
17: 36,678,387 (GRCm39) |
Y146C |
probably damaging |
Het |
| H2-Q7 |
C |
A |
17: 35,658,675 (GRCm39) |
S104R |
probably benign |
Het |
| Hephl1 |
T |
C |
9: 14,988,224 (GRCm39) |
Y628C |
probably damaging |
Het |
| Hspa5 |
T |
A |
2: 34,666,065 (GRCm39) |
Y636* |
probably null |
Het |
| Htt |
A |
G |
5: 35,063,092 (GRCm39) |
|
probably benign |
Het |
| Idh1 |
T |
C |
1: 65,200,273 (GRCm39) |
I364V |
probably benign |
Het |
| Itgae |
G |
T |
11: 73,007,988 (GRCm39) |
A423S |
possibly damaging |
Het |
| Kng2 |
T |
C |
16: 22,830,802 (GRCm39) |
N169S |
possibly damaging |
Het |
| Larp4b |
C |
T |
13: 9,201,235 (GRCm39) |
T369I |
possibly damaging |
Het |
| Lcor |
T |
C |
19: 41,573,387 (GRCm39) |
I714T |
probably benign |
Het |
| Lhfpl7 |
A |
G |
5: 113,382,435 (GRCm39) |
|
probably benign |
Het |
| Lonrf2 |
G |
A |
1: 38,852,357 (GRCm39) |
P165S |
probably benign |
Het |
| Mdn1 |
T |
A |
4: 32,720,761 (GRCm39) |
H2291Q |
probably damaging |
Het |
| Mgam |
T |
C |
6: 40,631,652 (GRCm39) |
|
probably null |
Het |
| Micall2 |
A |
G |
5: 139,702,508 (GRCm39) |
V245A |
probably benign |
Het |
| Mipep |
T |
G |
14: 61,109,512 (GRCm39) |
Y630D |
probably damaging |
Het |
| Msx2 |
A |
T |
13: 53,622,221 (GRCm39) |
M263K |
probably damaging |
Het |
| Nectin2 |
G |
T |
7: 19,451,633 (GRCm39) |
P467H |
probably damaging |
Het |
| Nek10 |
A |
T |
14: 14,842,789 (GRCm38) |
M165L |
probably benign |
Het |
| Nlrp4b |
A |
T |
7: 10,459,863 (GRCm39) |
M455L |
probably benign |
Het |
| Oaz3 |
TGGAGGCAGGAGCACGGGAGGCAGGAGCACGGGAGGCAG |
TGGAGGCAGGAGCACGGGAGGCAG |
3: 94,343,349 (GRCm39) |
|
probably benign |
Het |
| Or10ad1b |
T |
A |
15: 98,124,846 (GRCm39) |
I227F |
probably damaging |
Het |
| Or4c10 |
T |
A |
2: 89,760,645 (GRCm39) |
L164* |
probably null |
Het |
| Pcx |
T |
A |
19: 4,669,132 (GRCm39) |
V710E |
probably damaging |
Het |
| Pkn2 |
C |
T |
3: 142,527,408 (GRCm39) |
R347Q |
probably damaging |
Het |
| Pramel51 |
T |
C |
12: 88,145,218 (GRCm39) |
E44G |
possibly damaging |
Het |
| Qsox1 |
C |
T |
1: 155,666,791 (GRCm39) |
G233S |
probably benign |
Het |
| Rbl1 |
T |
A |
2: 157,037,475 (GRCm39) |
N224I |
probably damaging |
Het |
| Rspry1 |
A |
G |
8: 95,362,116 (GRCm39) |
T132A |
probably damaging |
Het |
| Sclt1 |
A |
G |
3: 41,681,546 (GRCm39) |
V91A |
probably damaging |
Het |
| Sema4f |
A |
T |
6: 82,895,540 (GRCm39) |
L331H |
probably benign |
Het |
| Sf3b3 |
T |
A |
8: 111,544,198 (GRCm39) |
Q814L |
probably benign |
Het |
| Slc19a2 |
T |
G |
1: 164,089,753 (GRCm39) |
Y190D |
probably damaging |
Het |
| Smarcc1 |
T |
A |
9: 109,982,879 (GRCm39) |
H204Q |
possibly damaging |
Het |
| Sox6 |
T |
C |
7: 115,376,328 (GRCm39) |
K135E |
probably damaging |
Het |
| Tecpr1 |
T |
C |
5: 144,145,426 (GRCm39) |
Q607R |
probably damaging |
Het |
| Tgfb1i1 |
A |
G |
7: 127,848,670 (GRCm39) |
|
probably benign |
Het |
| Tirap |
T |
G |
9: 35,099,999 (GRCm39) |
R228S |
probably benign |
Het |
| Trp53bp2 |
T |
A |
1: 182,256,581 (GRCm39) |
H50Q |
probably damaging |
Het |
| Try4 |
A |
G |
6: 41,280,365 (GRCm39) |
H63R |
probably damaging |
Het |
| Vmn2r25 |
G |
A |
6: 123,816,643 (GRCm39) |
P313S |
probably benign |
Het |
| Vps26a |
A |
C |
10: 62,294,825 (GRCm39) |
L250V |
probably benign |
Het |
| Vwf |
A |
G |
6: 125,619,000 (GRCm39) |
H1226R |
probably benign |
Het |
| Wdtc1 |
TCC |
TC |
4: 133,036,053 (GRCm39) |
|
probably benign |
Het |
| Zc3hav1l |
A |
T |
6: 38,274,881 (GRCm39) |
|
probably benign |
Het |
| Zfp119b |
T |
G |
17: 56,246,271 (GRCm39) |
H305P |
probably damaging |
Het |
| Zfp326 |
C |
T |
5: 106,039,035 (GRCm39) |
Q134* |
probably null |
Het |
| Zfp975 |
C |
T |
7: 42,311,263 (GRCm39) |
R450Q |
probably benign |
Het |
| Zfyve26 |
A |
T |
12: 79,333,032 (GRCm39) |
M313K |
probably benign |
Het |
| Zscan5b |
T |
C |
7: 6,241,965 (GRCm39) |
S395P |
possibly damaging |
Het |
|
| Other mutations in Magi2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00908:Magi2
|
APN |
5 |
20,596,299 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02120:Magi2
|
APN |
5 |
20,433,451 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02341:Magi2
|
APN |
5 |
20,671,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02411:Magi2
|
APN |
5 |
19,883,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02657:Magi2
|
APN |
5 |
19,432,581 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02976:Magi2
|
APN |
5 |
20,739,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03105:Magi2
|
APN |
5 |
20,748,616 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03246:Magi2
|
APN |
5 |
20,563,948 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03329:Magi2
|
APN |
5 |
20,671,126 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
LCD18:Magi2
|
UTSW |
5 |
20,159,509 (GRCm39) |
intron |
probably benign |
|
|
PIT4519001:Magi2
|
UTSW |
5 |
20,866,344 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Magi2
|
UTSW |
5 |
20,816,053 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0009:Magi2
|
UTSW |
5 |
20,816,053 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0352:Magi2
|
UTSW |
5 |
20,270,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0362:Magi2
|
UTSW |
5 |
19,432,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0496:Magi2
|
UTSW |
5 |
20,866,357 (GRCm39) |
splice site |
probably benign |
|
|
R1103:Magi2
|
UTSW |
5 |
20,816,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1435:Magi2
|
UTSW |
5 |
20,563,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1583:Magi2
|
UTSW |
5 |
19,432,330 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1616:Magi2
|
UTSW |
5 |
20,814,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1643:Magi2
|
UTSW |
5 |
20,910,504 (GRCm39) |
unclassified |
probably benign |
|
|
R1707:Magi2
|
UTSW |
5 |
20,420,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1837:Magi2
|
UTSW |
5 |
20,670,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1838:Magi2
|
UTSW |
5 |
20,670,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1839:Magi2
|
UTSW |
5 |
20,670,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Magi2
|
UTSW |
5 |
20,807,458 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2223:Magi2
|
UTSW |
5 |
20,670,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2496:Magi2
|
UTSW |
5 |
19,883,750 (GRCm39) |
missense |
probably benign |
0.42 |
|
R2504:Magi2
|
UTSW |
5 |
20,563,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2848:Magi2
|
UTSW |
5 |
20,807,459 (GRCm39) |
frame shift |
probably null |
|
|
R2879:Magi2
|
UTSW |
5 |
20,807,459 (GRCm39) |
frame shift |
probably null |
|
|
R2935:Magi2
|
UTSW |
5 |
20,807,459 (GRCm39) |
frame shift |
probably null |
|
|
R2936:Magi2
|
UTSW |
5 |
20,807,459 (GRCm39) |
frame shift |
probably null |
|
|
R3694:Magi2
|
UTSW |
5 |
20,807,459 (GRCm39) |
frame shift |
probably null |
|
|
R3783:Magi2
|
UTSW |
5 |
20,670,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3786:Magi2
|
UTSW |
5 |
20,670,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3787:Magi2
|
UTSW |
5 |
20,670,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3837:Magi2
|
UTSW |
5 |
20,420,466 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4151:Magi2
|
UTSW |
5 |
19,432,290 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4721:Magi2
|
UTSW |
5 |
20,739,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Magi2
|
UTSW |
5 |
20,739,444 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5012:Magi2
|
UTSW |
5 |
20,670,618 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5193:Magi2
|
UTSW |
5 |
20,563,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5298:Magi2
|
UTSW |
5 |
20,774,160 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5372:Magi2
|
UTSW |
5 |
20,907,108 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5580:Magi2
|
UTSW |
5 |
20,420,422 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5806:Magi2
|
UTSW |
5 |
20,856,202 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5924:Magi2
|
UTSW |
5 |
20,816,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5992:Magi2
|
UTSW |
5 |
19,432,289 (GRCm39) |
start codon destroyed |
probably null |
0.42 |
|
R6014:Magi2
|
UTSW |
5 |
20,816,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6073:Magi2
|
UTSW |
5 |
20,774,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6500:Magi2
|
UTSW |
5 |
20,807,345 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6664:Magi2
|
UTSW |
5 |
20,907,395 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7229:Magi2
|
UTSW |
5 |
20,670,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7344:Magi2
|
UTSW |
5 |
20,755,238 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7448:Magi2
|
UTSW |
5 |
20,563,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7605:Magi2
|
UTSW |
5 |
20,433,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7712:Magi2
|
UTSW |
5 |
20,755,280 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7808:Magi2
|
UTSW |
5 |
20,670,838 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7955:Magi2
|
UTSW |
5 |
20,594,070 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8134:Magi2
|
UTSW |
5 |
20,596,392 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8134:Magi2
|
UTSW |
5 |
20,596,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8253:Magi2
|
UTSW |
5 |
20,814,305 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8481:Magi2
|
UTSW |
5 |
20,594,152 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8553:Magi2
|
UTSW |
5 |
20,856,198 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8751:Magi2
|
UTSW |
5 |
20,739,462 (GRCm39) |
missense |
probably benign |
|
|
R8766:Magi2
|
UTSW |
5 |
20,400,123 (GRCm39) |
missense |
probably benign |
0.33 |
|
R8851:Magi2
|
UTSW |
5 |
20,270,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8876:Magi2
|
UTSW |
5 |
20,856,190 (GRCm39) |
nonsense |
probably null |
|
|
R9120:Magi2
|
UTSW |
5 |
20,733,305 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9335:Magi2
|
UTSW |
5 |
20,866,263 (GRCm39) |
missense |
|
|
|
R9367:Magi2
|
UTSW |
5 |
20,766,308 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9454:Magi2
|
UTSW |
5 |
20,671,176 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9474:Magi2
|
UTSW |
5 |
20,400,019 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9577:Magi2
|
UTSW |
5 |
20,814,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9673:Magi2
|
UTSW |
5 |
20,670,582 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9696:Magi2
|
UTSW |
5 |
20,670,864 (GRCm39) |
missense |
probably benign |
0.35 |
|
X0065:Magi2
|
UTSW |
5 |
20,774,176 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1176:Magi2
|
UTSW |
5 |
20,907,107 (GRCm39) |
missense |
probably benign |
0.32 |
|
Z1177:Magi2
|
UTSW |
5 |
20,907,410 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTCCCAAAGGACCCTCTGGAAC -3'
(R):5'- TGTTAATGCCATCCCCACGC -3'
Sequencing Primer
(F):5'- AGGCGACTCACCCTACTG -3'
(R):5'- TGCTTGACACACTTGAGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation