Mutagenetix > Incidental Mutation

Incidental Mutation 'R1835:Baz2b'

205138

Institutional Source

Beutler Lab

Gene Symbol

Baz2b

Ensembl Gene

ENSMUSG00000026987

Gene Name

bromodomain adjacent to zinc finger domain, 2B

Synonyms

D2Ertd794e, 5830435C13Rik

MMRRC Submission

039862-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.321) question?

Stock #

R1835 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

59899363-60209839 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 59901819 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 1994 (E1994G)

Ref Sequence

ENSEMBL: ENSMUSP00000108169 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000090925] [ENSMUST00000112550]

AlphaFold

A2AUY4

Predicted Effect

probably benign
Transcript: ENSMUST00000090925
AA Change: E1994G

PolyPhen 2 Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000088443
Gene: ENSMUSG00000026987
AA Change: E1994G

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	742	1e-12	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000112550
AA Change: E1994G

PolyPhen 2 Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000108169
Gene: ENSMUSG00000026987
AA Change: E1994G

Domain	Start	End	E-Value	Type
low complexity region	7	46	N/A	INTRINSIC
low complexity region	82	97	N/A	INTRINSIC
low complexity region	147	162	N/A	INTRINSIC
low complexity region	193	244	N/A	INTRINSIC
low complexity region	291	308	N/A	INTRINSIC
low complexity region	366	385	N/A	INTRINSIC
low complexity region	528	540	N/A	INTRINSIC
low complexity region	554	614	N/A	INTRINSIC
low complexity region	628	637	N/A	INTRINSIC
low complexity region	671	685	N/A	INTRINSIC
Pfam:MBD	690	741	3.4e-13	PFAM
low complexity region	759	774	N/A	INTRINSIC
coiled coil region	814	975	N/A	INTRINSIC
DDT	1004	1069	1.19e-20	SMART
low complexity region	1199	1212	N/A	INTRINSIC
low complexity region	1213	1247	N/A	INTRINSIC
coiled coil region	1251	1286	N/A	INTRINSIC
low complexity region	1320	1337	N/A	INTRINSIC
low complexity region	1503	1524	N/A	INTRINSIC
low complexity region	1569	1582	N/A	INTRINSIC
low complexity region	1585	1605	N/A	INTRINSIC
Pfam:WHIM3	1638	1676	5.1e-14	PFAM
Blast:BROMO	1802	1843	7e-18	BLAST
PHD	1888	1934	1.71e-12	SMART
low complexity region	1942	1964	N/A	INTRINSIC
low complexity region	1968	1980	N/A	INTRINSIC
BROMO	2013	2121	3.85e-41	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000130637

SMART Domains

Protein: ENSMUSP00000119690
Gene: ENSMUSG00000026987

Domain	Start	End	E-Value	Type
Pfam:WHIM3	2	37	1.8e-13	PFAM
low complexity region	162	173	N/A	INTRINSIC
PHD	214	253	2.05e-1	SMART

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 94.9%
20x: 91.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 97 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2610507B11Rik	G	T	11: 78,287,750 (GRCm38)	V1993F	probably damaging	Het
4933425L06Rik	C	A	13: 105,082,194 (GRCm38)	A12E	unknown	Het
Acss2	T	A	2: 155,558,630 (GRCm38)	Y530N	probably damaging	Het
Adam4	T	C	12: 81,419,559 (GRCm38)	I763V	probably benign	Het
Aipl1	T	G	11: 72,030,499 (GRCm38)	K190T	possibly damaging	Het
Alms1	T	A	6: 85,678,503 (GRCm38)	S3344T	possibly damaging	Het
Alpi	A	G	1: 87,099,414 (GRCm38)	V381A	possibly damaging	Het
Ankfn1	A	T	11: 89,447,618 (GRCm38)	S365R	probably benign	Het
Aox2	G	A	1: 58,308,991 (GRCm38)	A623T	probably benign	Het
Apc	T	A	18: 34,317,077 (GRCm38)	L2308Q	probably damaging	Het
Atp9b	C	T	18: 80,778,883 (GRCm38)	V501I	probably benign	Het
Cacna1a	T	C	8: 84,581,357 (GRCm38)		probably null	Het
Cacna1h	C	A	17: 25,392,076 (GRCm38)	V583L	probably benign	Het
Cd55	T	C	1: 130,447,609 (GRCm38)		probably benign	Het
Cep192	T	A	18: 67,804,424 (GRCm38)	S75T	possibly damaging	Het
Cfap54	T	A	10: 92,962,375 (GRCm38)	D1674V	probably benign	Het
Churc1	T	C	12: 76,773,297 (GRCm38)	F27L	possibly damaging	Het
Coro1c	A	G	5: 113,848,543 (GRCm38)	I280T	probably benign	Het
Creb1	C	T	1: 64,550,950 (GRCm38)	Q32*	probably null	Het
Cyp2b9	A	G	7: 26,200,783 (GRCm38)	T339A	probably benign	Het
Dctn3	T	C	4: 41,720,813 (GRCm38)	R51G	probably damaging	Het
Ddb1	T	C	19: 10,626,593 (GRCm38)	V888A	probably damaging	Het
Disp1	A	G	1: 183,089,000 (GRCm38)	Y619H	probably damaging	Het
Dnajc9	T	C	14: 20,388,334 (GRCm38)	D96G	possibly damaging	Het
Eepd1	A	G	9: 25,482,868 (GRCm38)	T143A	possibly damaging	Het
Eps8	T	A	6: 137,522,279 (GRCm38)	K204*	probably null	Het
Ercc5	T	A	1: 44,180,875 (GRCm38)	S1102R	probably benign	Het
Ergic2	T	A	6: 148,189,581 (GRCm38)	Y211F	possibly damaging	Het
Fam135b	G	T	15: 71,490,711 (GRCm38)	L274M	probably damaging	Het
Fat3	G	A	9: 15,998,088 (GRCm38)	T2206I	probably damaging	Het
Fat4	A	G	3: 38,983,571 (GRCm38)	I3791V	probably benign	Het
Gemin4	A	G	11: 76,213,296 (GRCm38)	M213T	possibly damaging	Het
Gnai3	T	C	3: 108,118,407 (GRCm38)	M119V	probably benign	Het
Heatr5b	A	T	17: 78,773,563 (GRCm38)	L1420Q	probably damaging	Het
Herc2	G	T	7: 56,206,765 (GRCm38)	G3918*	probably null	Het
Ints9	A	G	14: 65,032,256 (GRCm38)	Y465C	probably damaging	Het
Ist1	A	G	8: 109,678,883 (GRCm38)	V175A	probably damaging	Het
Kcnj12	T	C	11: 61,069,557 (GRCm38)	L227P	possibly damaging	Het
Kcnq5	T	C	1: 21,466,387 (GRCm38)	S416G	probably benign	Het
Kdm3a	T	A	6: 71,613,956 (GRCm38)	T295S	probably benign	Het
Kif1c	T	A	11: 70,708,971 (GRCm38)	M479K	probably damaging	Het
Kif20b	T	C	19: 34,956,038 (GRCm38)	L83P	probably damaging	Het
Kndc1	A	G	7: 139,927,711 (GRCm38)	E1194G	probably damaging	Het
Llgl1	A	G	11: 60,704,730 (GRCm38)	M81V	probably benign	Het
Map4k5	C	A	12: 69,824,662 (GRCm38)	M495I	probably damaging	Het
Mest	C	T	6: 30,742,791 (GRCm38)	R146C	probably benign	Het
Mettl24	T	A	10: 40,737,816 (GRCm38)		probably null	Het
Mical1	T	C	10: 41,483,535 (GRCm38)	S586P	probably benign	Het
Mrgpra3	G	T	7: 47,589,946 (GRCm38)	Y77*	probably null	Het
Mss51	A	T	14: 20,483,178 (GRCm38)	C408*	probably null	Het
Myh6	T	C	14: 54,957,401 (GRCm38)	T666A	probably benign	Het
Myo10	T	C	15: 25,805,587 (GRCm38)	C1685R	possibly damaging	Het
Naip5	A	T	13: 100,223,218 (GRCm38)	Y503*	probably null	Het
Neil1	A	C	9: 57,146,604 (GRCm38)	F144C	probably damaging	Het
Nipbl	T	A	15: 8,343,517 (GRCm38)	I1082F	possibly damaging	Het
Nkiras1	T	C	14: 18,276,732 (GRCm38)	V7A	probably damaging	Het
Ntng2	G	A	2: 29,197,057 (GRCm38)	Q384*	probably null	Het
Ocrl	T	A	X: 47,962,116 (GRCm38)	I74N	probably damaging	Het
Olfr137	A	T	17: 38,305,312 (GRCm38)	S50T	probably benign	Het
Olfr1385	A	T	11: 49,494,670 (GRCm38)	I46F	probably damaging	Het
Olfr1408	A	G	1: 173,130,815 (GRCm38)	V134A	probably benign	Het
Olfr381	A	C	11: 73,486,374 (GRCm38)	V150G	probably benign	Het
Olfr535	A	G	7: 140,492,709 (GRCm38)	S24G	probably benign	Het
Olfr761	C	T	17: 37,952,385 (GRCm38)	G213E	possibly damaging	Het
Patj	A	G	4: 98,491,590 (GRCm38)	D151G	probably benign	Het
Plpbp	T	C	8: 27,049,231 (GRCm38)	V126A	probably damaging	Het
Pold2	A	G	11: 5,873,454 (GRCm38)	L325P	possibly damaging	Het
Ppp1r12c	A	C	7: 4,483,651 (GRCm38)	S480A	probably damaging	Het
Pum1	T	C	4: 130,701,048 (GRCm38)	S124P	possibly damaging	Het
Pwp2	C	G	10: 78,179,091 (GRCm38)	G353A	probably damaging	Het
Reln	C	A	5: 21,979,002 (GRCm38)	Q1666H	probably damaging	Het
Rnf19a	T	C	15: 36,265,925 (GRCm38)	I9V	probably benign	Het
Ryr2	T	C	13: 11,769,878 (GRCm38)	H1063R	probably benign	Het
Samd14	C	G	11: 95,023,600 (GRCm38)	D361E	probably damaging	Het
Samd15	A	T	12: 87,201,843 (GRCm38)	N365I	probably damaging	Het
Sec16b	A	G	1: 157,531,312 (GRCm38)	H105R	probably benign	Het
Sez6	T	C	11: 77,953,503 (GRCm38)	S51P	probably benign	Het
Sh3bp1	T	A	15: 78,905,150 (GRCm38)	L236Q	probably damaging	Het
Sspo	C	T	6: 48,457,340 (GRCm38)	T991I	probably damaging	Het
Suco	A	T	1: 161,859,500 (GRCm38)	L97*	probably null	Het
Tab1	C	A	15: 80,148,296 (GRCm38)	R35S	probably benign	Het
Tet3	C	A	6: 83,404,163 (GRCm38)	S341I	possibly damaging	Het
Tlr1	A	T	5: 64,925,700 (GRCm38)	D511E	probably benign	Het
Tmem132b	A	C	5: 125,785,899 (GRCm38)	D656A	probably damaging	Het
Tmtc4	T	A	14: 122,941,988 (GRCm38)		probably null	Het
Trmo	T	C	4: 46,380,158 (GRCm38)	T404A	probably damaging	Het
Trpm1	A	G	7: 64,230,268 (GRCm38)	K790E	probably damaging	Het
Ulk4	C	A	9: 121,168,184 (GRCm38)	R774M	probably null	Het
Ush2a	C	T	1: 188,451,818 (GRCm38)	L1440F	probably benign	Het
Usp16	A	G	16: 87,480,907 (GRCm38)	K682E	probably damaging	Het
Virma	T	C	4: 11,540,511 (GRCm38)	S1471P	probably benign	Het
Vmn1r177	A	T	7: 23,865,686 (GRCm38)	I255N	probably damaging	Het
Vmn2r61	A	T	7: 42,266,652 (GRCm38)	R230*	probably null	Het
Vps13c	T	A	9: 67,993,013 (GRCm38)	F3671L	probably benign	Het
Washc5	T	C	15: 59,359,340 (GRCm38)	N358S	possibly damaging	Het
Wdr72	A	G	9: 74,151,617 (GRCm38)	K331E	probably damaging	Het
Zfp986	A	T	4: 145,899,235 (GRCm38)	K155I	probably benign	Het

Other mutations in Baz2b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00430:Baz2b	APN	2	59,912,795 (GRCm38)	missense	probably benign	0.02
IGL00476:Baz2b	APN	2	59,913,739 (GRCm38)	missense	probably benign	0.06
IGL00489:Baz2b	APN	2	59,957,675 (GRCm38)	nonsense	probably null
IGL00514:Baz2b	APN	2	59,962,477 (GRCm38)	missense	probably benign	0.11
IGL00678:Baz2b	APN	2	60,006,183 (GRCm38)	missense	unknown
IGL01348:Baz2b	APN	2	59,933,687 (GRCm38)	missense	possibly damaging	0.95
IGL01354:Baz2b	APN	2	59,968,889 (GRCm38)	missense	probably benign	0.18
IGL01924:Baz2b	APN	2	59,935,271 (GRCm38)	missense	probably damaging	1.00
IGL02125:Baz2b	APN	2	59,968,640 (GRCm38)	missense	probably benign	0.12
IGL02314:Baz2b	APN	2	59,962,227 (GRCm38)	missense	probably benign
IGL02370:Baz2b	APN	2	59,923,589 (GRCm38)	missense	possibly damaging	0.77
IGL02473:Baz2b	APN	2	59,960,063 (GRCm38)	missense	probably benign	0.40
IGL02499:Baz2b	APN	2	59,901,496 (GRCm38)	missense	possibly damaging	0.60
IGL02609:Baz2b	APN	2	59,917,369 (GRCm38)	missense	possibly damaging	0.77
IGL02705:Baz2b	APN	2	59,948,260 (GRCm38)	missense	possibly damaging	0.92
IGL02711:Baz2b	APN	2	59,917,505 (GRCm38)	unclassified	probably benign
IGL02716:Baz2b	APN	2	59,962,524 (GRCm38)	missense	possibly damaging	0.53
IGL02724:Baz2b	APN	2	59,977,374 (GRCm38)	missense	possibly damaging	0.70
IGL02750:Baz2b	APN	2	59,968,658 (GRCm38)	missense	possibly damaging	0.73
IGL02869:Baz2b	APN	2	59,977,528 (GRCm38)	missense	probably benign	0.00
IGL02886:Baz2b	APN	2	59,957,743 (GRCm38)	splice site	probably null
IGL02892:Baz2b	APN	2	59,900,736 (GRCm38)	missense	probably damaging	1.00
IGL03132:Baz2b	APN	2	59,907,753 (GRCm38)	splice site	probably benign
IGL03183:Baz2b	APN	2	59,903,296 (GRCm38)	missense	probably benign	0.10
IGL03197:Baz2b	APN	2	59,901,554 (GRCm38)	missense	possibly damaging	0.74
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0054:Baz2b	UTSW	2	59,932,166 (GRCm38)	missense	probably damaging	1.00
R0122:Baz2b	UTSW	2	59,913,619 (GRCm38)	splice site	probably null
R0136:Baz2b	UTSW	2	59,901,954 (GRCm38)	missense	probably benign	0.22
R0144:Baz2b	UTSW	2	59,907,495 (GRCm38)	missense	probably damaging	0.98
R0403:Baz2b	UTSW	2	59,969,377 (GRCm38)	missense	possibly damaging	0.70
R0498:Baz2b	UTSW	2	59,901,996 (GRCm38)	unclassified	probably benign
R0528:Baz2b	UTSW	2	59,936,739 (GRCm38)	missense	probably damaging	1.00
R1025:Baz2b	UTSW	2	59,962,482 (GRCm38)	missense	probably benign	0.06
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1470:Baz2b	UTSW	2	59,978,546 (GRCm38)	missense	possibly damaging	0.53
R1510:Baz2b	UTSW	2	59,922,209 (GRCm38)	missense	probably damaging	1.00
R1511:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R1514:Baz2b	UTSW	2	59,962,326 (GRCm38)	missense	probably benign	0.13
R1519:Baz2b	UTSW	2	59,948,254 (GRCm38)	missense	possibly damaging	0.50
R1523:Baz2b	UTSW	2	59,968,637 (GRCm38)	missense	possibly damaging	0.47
R1630:Baz2b	UTSW	2	60,006,130 (GRCm38)	missense	unknown
R1641:Baz2b	UTSW	2	59,912,890 (GRCm38)	missense	probably damaging	0.99
R1674:Baz2b	UTSW	2	59,912,992 (GRCm38)	missense	possibly damaging	0.53
R1778:Baz2b	UTSW	2	60,006,136 (GRCm38)	missense	unknown
R1826:Baz2b	UTSW	2	59,968,733 (GRCm38)	missense	probably benign	0.12
R1954:Baz2b	UTSW	2	59,968,743 (GRCm38)	missense	probably benign	0.12
R1981:Baz2b	UTSW	2	59,923,680 (GRCm38)	missense	possibly damaging	0.95
R2029:Baz2b	UTSW	2	59,912,723 (GRCm38)	unclassified	probably benign
R2567:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	possibly damaging	0.82
R2842:Baz2b	UTSW	2	59,913,004 (GRCm38)	missense	probably benign	0.27
R2848:Baz2b	UTSW	2	59,924,666 (GRCm38)	missense	possibly damaging	0.64
R3809:Baz2b	UTSW	2	59,968,896 (GRCm38)	missense	probably benign	0.12
R3935:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R3936:Baz2b	UTSW	2	59,912,761 (GRCm38)	missense	possibly damaging	0.81
R4072:Baz2b	UTSW	2	59,912,573 (GRCm38)	splice site	probably null
R4182:Baz2b	UTSW	2	60,098,457 (GRCm38)	intron	probably benign
R4255:Baz2b	UTSW	2	59,920,572 (GRCm38)	unclassified	probably benign
R4359:Baz2b	UTSW	2	59,901,613 (GRCm38)	missense	possibly damaging	0.87
R4716:Baz2b	UTSW	2	59,969,255 (GRCm38)	missense	probably benign	0.06
R4743:Baz2b	UTSW	2	59,913,911 (GRCm38)	missense	probably benign	0.01
R4772:Baz2b	UTSW	2	59,958,451 (GRCm38)	missense	probably damaging	0.96
R4858:Baz2b	UTSW	2	59,907,743 (GRCm38)	missense	probably benign
R4868:Baz2b	UTSW	2	59,924,882 (GRCm38)	missense	possibly damaging	0.65
R4872:Baz2b	UTSW	2	59,942,759 (GRCm38)	splice site	probably null
R4889:Baz2b	UTSW	2	59,936,726 (GRCm38)	missense	probably damaging	1.00
R4890:Baz2b	UTSW	2	59,926,039 (GRCm38)	missense	probably damaging	0.99
R4914:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4915:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R4918:Baz2b	UTSW	2	59,914,043 (GRCm38)	missense	possibly damaging	0.70
R5027:Baz2b	UTSW	2	60,098,644 (GRCm38)	intron	probably benign
R5031:Baz2b	UTSW	2	59,912,807 (GRCm38)	missense	probably benign	0.00
R5082:Baz2b	UTSW	2	59,901,491 (GRCm38)	nonsense	probably null
R5133:Baz2b	UTSW	2	59,962,024 (GRCm38)	missense	probably benign	0.12
R5276:Baz2b	UTSW	2	59,962,614 (GRCm38)	missense	probably benign	0.40
R5279:Baz2b	UTSW	2	59,932,152 (GRCm38)	missense	probably damaging	1.00
R5294:Baz2b	UTSW	2	59,978,602 (GRCm38)	missense	probably benign	0.11
R5447:Baz2b	UTSW	2	59,913,988 (GRCm38)	missense	probably damaging	0.99
R5903:Baz2b	UTSW	2	59,959,889 (GRCm38)	missense	probably damaging	0.99
R5910:Baz2b	UTSW	2	59,977,426 (GRCm38)	missense	possibly damaging	0.88
R6140:Baz2b	UTSW	2	59,912,527 (GRCm38)	missense	probably damaging	0.99
R6195:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6199:Baz2b	UTSW	2	59,978,675 (GRCm38)	missense	probably benign	0.00
R6208:Baz2b	UTSW	2	59,924,806 (GRCm38)	missense	probably damaging	1.00
R6233:Baz2b	UTSW	2	59,907,511 (GRCm38)	missense	possibly damaging	0.89
R6276:Baz2b	UTSW	2	59,948,223 (GRCm38)	missense	probably damaging	1.00
R6324:Baz2b	UTSW	2	59,906,948 (GRCm38)	missense	probably damaging	1.00
R6490:Baz2b	UTSW	2	59,901,729 (GRCm38)	missense	probably damaging	1.00
R6578:Baz2b	UTSW	2	59,969,279 (GRCm38)	missense	possibly damaging	0.47
R6720:Baz2b	UTSW	2	59,924,890 (GRCm38)	missense	probably damaging	1.00
R6760:Baz2b	UTSW	2	59,962,432 (GRCm38)	missense	probably benign	0.40
R6836:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R6859:Baz2b	UTSW	2	59,901,530 (GRCm38)	missense	probably benign	0.01
R6880:Baz2b	UTSW	2	59,912,939 (GRCm38)	missense	probably damaging	0.99
R6916:Baz2b	UTSW	2	59,968,776 (GRCm38)	missense	probably benign
R6978:Baz2b	UTSW	2	59,907,715 (GRCm38)	missense	possibly damaging	0.84
R7037:Baz2b	UTSW	2	59,933,670 (GRCm38)	critical splice donor site	probably null
R7112:Baz2b	UTSW	2	59,962,184 (GRCm38)	missense	possibly damaging	0.53
R7117:Baz2b	UTSW	2	59,912,497 (GRCm38)	missense
R7198:Baz2b	UTSW	2	59,962,206 (GRCm38)	missense	probably benign	0.00
R7270:Baz2b	UTSW	2	59,962,492 (GRCm38)	missense	possibly damaging	0.96
R7282:Baz2b	UTSW	2	59,920,437 (GRCm38)	missense	probably benign	0.17
R7464:Baz2b	UTSW	2	59,977,448 (GRCm38)	missense	possibly damaging	0.53
R7609:Baz2b	UTSW	2	59,962,473 (GRCm38)	missense	probably benign	0.40
R7703:Baz2b	UTSW	2	59,917,425 (GRCm38)	missense	probably damaging	1.00
R7850:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7851:Baz2b	UTSW	2	59,936,716 (GRCm38)	missense	probably damaging	0.98
R7988:Baz2b	UTSW	2	59,962,141 (GRCm38)	missense	possibly damaging	0.53
R8079:Baz2b	UTSW	2	59,900,768 (GRCm38)	missense	probably damaging	1.00
R8084:Baz2b	UTSW	2	59,962,236 (GRCm38)	missense	probably benign
R8343:Baz2b	UTSW	2	59,901,514 (GRCm38)	missense	probably damaging	1.00
R8348:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8438:Baz2b	UTSW	2	59,917,484 (GRCm38)	nonsense	probably null
R8448:Baz2b	UTSW	2	59,911,793 (GRCm38)	missense
R8511:Baz2b	UTSW	2	59,901,814 (GRCm38)	missense	probably benign
R8893:Baz2b	UTSW	2	59,924,805 (GRCm38)	missense	probably damaging	0.96
R8947:Baz2b	UTSW	2	59,948,239 (GRCm38)	missense	probably benign	0.06
R8998:Baz2b	UTSW	2	59,969,264 (GRCm38)	missense	probably benign	0.02
R9241:Baz2b	UTSW	2	59,913,649 (GRCm38)	missense	probably benign	0.01
R9245:Baz2b	UTSW	2	59,912,987 (GRCm38)	missense	probably benign
R9577:Baz2b	UTSW	2	59,978,687 (GRCm38)	missense	probably benign	0.06
R9581:Baz2b	UTSW	2	59,968,956 (GRCm38)	missense	probably benign
R9601:Baz2b	UTSW	2	59,901,503 (GRCm38)	missense	possibly damaging	0.66
R9613:Baz2b	UTSW	2	59,901,480 (GRCm38)	missense	probably benign	0.09
R9639:Baz2b	UTSW	2	59,901,484 (GRCm38)	missense	probably benign	0.01
X0011:Baz2b	UTSW	2	59,977,361 (GRCm38)	missense	possibly damaging	0.53
X0053:Baz2b	UTSW	2	59,900,675 (GRCm38)	missense	probably damaging	1.00
X0064:Baz2b	UTSW	2	59,969,282 (GRCm38)	missense	probably benign
Z1088:Baz2b	UTSW	2	59,960,015 (GRCm38)	missense	probably damaging	1.00
Z1177:Baz2b	UTSW	2	59,977,520 (GRCm38)	missense	probably benign	0.01
Z1188:Baz2b	UTSW	2	59,977,405 (GRCm38)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- TCGGTACCTAGACCTTGGAACG -3'
(R):5'- GCAGCCGCTTTCTTATACAC -3'

Sequencing Primer
(F):5'- TAGACCTTGGAACGGCCCAAAG -3'
(R):5'- CTTTTTAATTAAAGGCAAGCGGC -3'

Posted On

2014-06-23