Incidental Mutation 'R1835:Heatr5b'
| ID |
205227 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Heatr5b
|
| Ensembl Gene |
ENSMUSG00000039414 |
| Gene Name |
HEAT repeat containing 5B |
| Synonyms |
2010013B10Rik, A230048G03Rik, D330050P16Rik |
| MMRRC Submission |
039862-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.633)
|
| Stock # |
R1835 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
78752906-78835381 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 78773563 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Glutamine
at position 1420
(L1420Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000094882
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000097281]
|
| AlphaFold |
Q8C547 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000097281
AA Change: L1420Q
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000094882
Gene: ENSMUSG00000039414
AA Change: L1420Q
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1qbkb_
|
46 |
491 |
4e-6 |
SMART |
|
SCOP:d1qbkb_
|
846 |
1338 |
2e-16 |
SMART |
|
low complexity region
|
1641 |
1650 |
N/A |
INTRINSIC |
|
low complexity region
|
2039 |
2057 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
T |
A |
2: 155,558,630 (GRCm38) |
Y530N |
probably damaging |
Het |
| Adam4 |
T |
C |
12: 81,419,559 (GRCm38) |
I763V |
probably benign |
Het |
| Aipl1 |
T |
G |
11: 72,030,499 (GRCm38) |
K190T |
possibly damaging |
Het |
| Alms1 |
T |
A |
6: 85,678,503 (GRCm38) |
S3344T |
possibly damaging |
Het |
| Alpi |
A |
G |
1: 87,099,414 (GRCm38) |
V381A |
possibly damaging |
Het |
| Ankfn1 |
A |
T |
11: 89,447,618 (GRCm38) |
S365R |
probably benign |
Het |
| Aox2 |
G |
A |
1: 58,308,991 (GRCm38) |
A623T |
probably benign |
Het |
| Apc |
T |
A |
18: 34,317,077 (GRCm38) |
L2308Q |
probably damaging |
Het |
| Atp9b |
C |
T |
18: 80,778,883 (GRCm38) |
V501I |
probably benign |
Het |
| Baz2b |
T |
C |
2: 59,901,819 (GRCm38) |
E1994G |
probably benign |
Het |
| Bltp2 |
G |
T |
11: 78,287,750 (GRCm38) |
V1993F |
probably damaging |
Het |
| Cacna1a |
T |
C |
8: 84,581,357 (GRCm38) |
|
probably null |
Het |
| Cacna1h |
C |
A |
17: 25,392,076 (GRCm38) |
V583L |
probably benign |
Het |
| Cd55 |
T |
C |
1: 130,447,609 (GRCm38) |
|
probably benign |
Het |
| Cep192 |
T |
A |
18: 67,804,424 (GRCm38) |
S75T |
possibly damaging |
Het |
| Cfap54 |
T |
A |
10: 92,962,375 (GRCm38) |
D1674V |
probably benign |
Het |
| Churc1 |
T |
C |
12: 76,773,297 (GRCm38) |
F27L |
possibly damaging |
Het |
| Coro1c |
A |
G |
5: 113,848,543 (GRCm38) |
I280T |
probably benign |
Het |
| Creb1 |
C |
T |
1: 64,550,950 (GRCm38) |
Q32* |
probably null |
Het |
| Cyp2b9 |
A |
G |
7: 26,200,783 (GRCm38) |
T339A |
probably benign |
Het |
| Dctn3 |
T |
C |
4: 41,720,813 (GRCm38) |
R51G |
probably damaging |
Het |
| Ddb1 |
T |
C |
19: 10,626,593 (GRCm38) |
V888A |
probably damaging |
Het |
| Disp1 |
A |
G |
1: 183,089,000 (GRCm38) |
Y619H |
probably damaging |
Het |
| Dnajc9 |
T |
C |
14: 20,388,334 (GRCm38) |
D96G |
possibly damaging |
Het |
| Eepd1 |
A |
G |
9: 25,482,868 (GRCm38) |
T143A |
possibly damaging |
Het |
| Eps8 |
T |
A |
6: 137,522,279 (GRCm38) |
K204* |
probably null |
Het |
| Ercc5 |
T |
A |
1: 44,180,875 (GRCm38) |
S1102R |
probably benign |
Het |
| Ergic2 |
T |
A |
6: 148,189,581 (GRCm38) |
Y211F |
possibly damaging |
Het |
| Fam135b |
G |
T |
15: 71,490,711 (GRCm38) |
L274M |
probably damaging |
Het |
| Fat3 |
G |
A |
9: 15,998,088 (GRCm38) |
T2206I |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 38,983,571 (GRCm38) |
I3791V |
probably benign |
Het |
| Gemin4 |
A |
G |
11: 76,213,296 (GRCm38) |
M213T |
possibly damaging |
Het |
| Gnai3 |
T |
C |
3: 108,118,407 (GRCm38) |
M119V |
probably benign |
Het |
| Herc2 |
G |
T |
7: 56,206,765 (GRCm38) |
G3918* |
probably null |
Het |
| Ints9 |
A |
G |
14: 65,032,256 (GRCm38) |
Y465C |
probably damaging |
Het |
| Ist1 |
A |
G |
8: 109,678,883 (GRCm38) |
V175A |
probably damaging |
Het |
| Kcnj12 |
T |
C |
11: 61,069,557 (GRCm38) |
L227P |
possibly damaging |
Het |
| Kcnq5 |
T |
C |
1: 21,466,387 (GRCm38) |
S416G |
probably benign |
Het |
| Kdm3a |
T |
A |
6: 71,613,956 (GRCm38) |
T295S |
probably benign |
Het |
| Kif1c |
T |
A |
11: 70,708,971 (GRCm38) |
M479K |
probably damaging |
Het |
| Kif20b |
T |
C |
19: 34,956,038 (GRCm38) |
L83P |
probably damaging |
Het |
| Kndc1 |
A |
G |
7: 139,927,711 (GRCm38) |
E1194G |
probably damaging |
Het |
| Llgl1 |
A |
G |
11: 60,704,730 (GRCm38) |
M81V |
probably benign |
Het |
| Map4k5 |
C |
A |
12: 69,824,662 (GRCm38) |
M495I |
probably damaging |
Het |
| Mest |
C |
T |
6: 30,742,791 (GRCm38) |
R146C |
probably benign |
Het |
| Mettl24 |
T |
A |
10: 40,737,816 (GRCm38) |
|
probably null |
Het |
| Mical1 |
T |
C |
10: 41,483,535 (GRCm38) |
S586P |
probably benign |
Het |
| Mrgpra3 |
G |
T |
7: 47,589,946 (GRCm38) |
Y77* |
probably null |
Het |
| Mss51 |
A |
T |
14: 20,483,178 (GRCm38) |
C408* |
probably null |
Het |
| Myh6 |
T |
C |
14: 54,957,401 (GRCm38) |
T666A |
probably benign |
Het |
| Myo10 |
T |
C |
15: 25,805,587 (GRCm38) |
C1685R |
possibly damaging |
Het |
| Naip5 |
A |
T |
13: 100,223,218 (GRCm38) |
Y503* |
probably null |
Het |
| Neil1 |
A |
C |
9: 57,146,604 (GRCm38) |
F144C |
probably damaging |
Het |
| Nipbl |
T |
A |
15: 8,343,517 (GRCm38) |
I1082F |
possibly damaging |
Het |
| Nkiras1 |
T |
C |
14: 18,276,732 (GRCm38) |
V7A |
probably damaging |
Het |
| Nt5el |
C |
A |
13: 105,082,194 (GRCm38) |
A12E |
unknown |
Het |
| Ntng2 |
G |
A |
2: 29,197,057 (GRCm38) |
Q384* |
probably null |
Het |
| Ocrl |
T |
A |
X: 47,962,116 (GRCm38) |
I74N |
probably damaging |
Het |
| Or10j27 |
A |
G |
1: 173,130,815 (GRCm38) |
V134A |
probably benign |
Het |
| Or13a22 |
A |
G |
7: 140,492,709 (GRCm38) |
S24G |
probably benign |
Het |
| Or14j8 |
C |
T |
17: 37,952,385 (GRCm38) |
G213E |
possibly damaging |
Het |
| Or1e22 |
A |
C |
11: 73,486,374 (GRCm38) |
V150G |
probably benign |
Het |
| Or2j3 |
A |
T |
17: 38,305,312 (GRCm38) |
S50T |
probably benign |
Het |
| Or2y1 |
A |
T |
11: 49,494,670 (GRCm38) |
I46F |
probably damaging |
Het |
| Patj |
A |
G |
4: 98,491,590 (GRCm38) |
D151G |
probably benign |
Het |
| Plpbp |
T |
C |
8: 27,049,231 (GRCm38) |
V126A |
probably damaging |
Het |
| Pold2 |
A |
G |
11: 5,873,454 (GRCm38) |
L325P |
possibly damaging |
Het |
| Ppp1r12c |
A |
C |
7: 4,483,651 (GRCm38) |
S480A |
probably damaging |
Het |
| Pum1 |
T |
C |
4: 130,701,048 (GRCm38) |
S124P |
possibly damaging |
Het |
| Pwp2 |
C |
G |
10: 78,179,091 (GRCm38) |
G353A |
probably damaging |
Het |
| Reln |
C |
A |
5: 21,979,002 (GRCm38) |
Q1666H |
probably damaging |
Het |
| Rnf19a |
T |
C |
15: 36,265,925 (GRCm38) |
I9V |
probably benign |
Het |
| Ryr2 |
T |
C |
13: 11,769,878 (GRCm38) |
H1063R |
probably benign |
Het |
| Samd14 |
C |
G |
11: 95,023,600 (GRCm38) |
D361E |
probably damaging |
Het |
| Samd15 |
A |
T |
12: 87,201,843 (GRCm38) |
N365I |
probably damaging |
Het |
| Sec16b |
A |
G |
1: 157,531,312 (GRCm38) |
H105R |
probably benign |
Het |
| Sez6 |
T |
C |
11: 77,953,503 (GRCm38) |
S51P |
probably benign |
Het |
| Sh3bp1 |
T |
A |
15: 78,905,150 (GRCm38) |
L236Q |
probably damaging |
Het |
| Sspo |
C |
T |
6: 48,457,340 (GRCm38) |
T991I |
probably damaging |
Het |
| Suco |
A |
T |
1: 161,859,500 (GRCm38) |
L97* |
probably null |
Het |
| Tab1 |
C |
A |
15: 80,148,296 (GRCm38) |
R35S |
probably benign |
Het |
| Tet3 |
C |
A |
6: 83,404,163 (GRCm38) |
S341I |
possibly damaging |
Het |
| Tlr1 |
A |
T |
5: 64,925,700 (GRCm38) |
D511E |
probably benign |
Het |
| Tmem132b |
A |
C |
5: 125,785,899 (GRCm38) |
D656A |
probably damaging |
Het |
| Tmtc4 |
T |
A |
14: 122,941,988 (GRCm38) |
|
probably null |
Het |
| Trmo |
T |
C |
4: 46,380,158 (GRCm38) |
T404A |
probably damaging |
Het |
| Trpm1 |
A |
G |
7: 64,230,268 (GRCm38) |
K790E |
probably damaging |
Het |
| Ulk4 |
C |
A |
9: 121,168,184 (GRCm38) |
R774M |
probably null |
Het |
| Ush2a |
C |
T |
1: 188,451,818 (GRCm38) |
L1440F |
probably benign |
Het |
| Usp16 |
A |
G |
16: 87,480,907 (GRCm38) |
K682E |
probably damaging |
Het |
| Virma |
T |
C |
4: 11,540,511 (GRCm38) |
S1471P |
probably benign |
Het |
| Vmn1r177 |
A |
T |
7: 23,865,686 (GRCm38) |
I255N |
probably damaging |
Het |
| Vmn2r61 |
A |
T |
7: 42,266,652 (GRCm38) |
R230* |
probably null |
Het |
| Vps13c |
T |
A |
9: 67,993,013 (GRCm38) |
F3671L |
probably benign |
Het |
| Washc5 |
T |
C |
15: 59,359,340 (GRCm38) |
N358S |
possibly damaging |
Het |
| Wdr72 |
A |
G |
9: 74,151,617 (GRCm38) |
K331E |
probably damaging |
Het |
| Zfp986 |
A |
T |
4: 145,899,235 (GRCm38) |
K155I |
probably benign |
Het |
|
| Other mutations in Heatr5b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00338:Heatr5b
|
APN |
17 |
78,803,434 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00418:Heatr5b
|
APN |
17 |
78,753,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00786:Heatr5b
|
APN |
17 |
78,824,634 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL00840:Heatr5b
|
APN |
17 |
78,765,437 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01362:Heatr5b
|
APN |
17 |
78,816,338 (GRCm38) |
splice site |
probably benign |
|
|
IGL01419:Heatr5b
|
APN |
17 |
78,796,510 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL01447:Heatr5b
|
APN |
17 |
78,829,597 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01591:Heatr5b
|
APN |
17 |
78,808,472 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL01743:Heatr5b
|
APN |
17 |
78,824,640 (GRCm38) |
nonsense |
probably null |
|
|
IGL01860:Heatr5b
|
APN |
17 |
78,808,480 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01862:Heatr5b
|
APN |
17 |
78,796,485 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
IGL01984:Heatr5b
|
APN |
17 |
78,796,497 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
IGL02045:Heatr5b
|
APN |
17 |
78,808,426 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02097:Heatr5b
|
APN |
17 |
78,817,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02168:Heatr5b
|
APN |
17 |
78,831,591 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02399:Heatr5b
|
APN |
17 |
78,827,967 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02540:Heatr5b
|
APN |
17 |
78,773,572 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02719:Heatr5b
|
APN |
17 |
78,815,540 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02824:Heatr5b
|
APN |
17 |
78,773,680 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02965:Heatr5b
|
APN |
17 |
78,753,073 (GRCm38) |
missense |
probably benign |
0.37 |
|
IGL03032:Heatr5b
|
APN |
17 |
78,760,499 (GRCm38) |
missense |
probably benign |
0.45 |
|
IGL03243:Heatr5b
|
APN |
17 |
78,763,080 (GRCm38) |
splice site |
probably benign |
|
|
IGL03259:Heatr5b
|
APN |
17 |
78,791,556 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03349:Heatr5b
|
APN |
17 |
78,755,320 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5470_heatr5b_501
|
UTSW |
17 |
78,821,579 (GRCm38) |
splice site |
probably null |
|
|
R0124:Heatr5b
|
UTSW |
17 |
78,826,217 (GRCm38) |
splice site |
probably benign |
|
|
R0285:Heatr5b
|
UTSW |
17 |
78,808,453 (GRCm38) |
missense |
probably benign |
0.05 |
|
R0335:Heatr5b
|
UTSW |
17 |
78,827,946 (GRCm38) |
missense |
probably benign |
0.15 |
|
R0412:Heatr5b
|
UTSW |
17 |
78,820,854 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0601:Heatr5b
|
UTSW |
17 |
78,768,545 (GRCm38) |
missense |
probably benign |
|
|
R0725:Heatr5b
|
UTSW |
17 |
78,796,396 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1178:Heatr5b
|
UTSW |
17 |
78,813,269 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1444:Heatr5b
|
UTSW |
17 |
78,755,427 (GRCm38) |
splice site |
probably benign |
|
|
R1444:Heatr5b
|
UTSW |
17 |
78,753,193 (GRCm38) |
missense |
probably benign |
0.17 |
|
R1453:Heatr5b
|
UTSW |
17 |
78,817,563 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1469:Heatr5b
|
UTSW |
17 |
78,808,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1469:Heatr5b
|
UTSW |
17 |
78,808,384 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1506:Heatr5b
|
UTSW |
17 |
78,753,147 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1819:Heatr5b
|
UTSW |
17 |
78,791,511 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1837:Heatr5b
|
UTSW |
17 |
78,820,751 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R1934:Heatr5b
|
UTSW |
17 |
78,795,918 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2014:Heatr5b
|
UTSW |
17 |
78,814,184 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2037:Heatr5b
|
UTSW |
17 |
78,829,505 (GRCm38) |
nonsense |
probably null |
|
|
R2154:Heatr5b
|
UTSW |
17 |
78,831,444 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2190:Heatr5b
|
UTSW |
17 |
78,801,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2191:Heatr5b
|
UTSW |
17 |
78,773,677 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2413:Heatr5b
|
UTSW |
17 |
78,756,861 (GRCm38) |
critical splice donor site |
probably null |
|
|
R3424:Heatr5b
|
UTSW |
17 |
78,768,404 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R3607:Heatr5b
|
UTSW |
17 |
78,834,217 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3759:Heatr5b
|
UTSW |
17 |
78,824,540 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R3761:Heatr5b
|
UTSW |
17 |
78,829,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4127:Heatr5b
|
UTSW |
17 |
78,753,174 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R4242:Heatr5b
|
UTSW |
17 |
78,756,922 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4345:Heatr5b
|
UTSW |
17 |
78,760,511 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4534:Heatr5b
|
UTSW |
17 |
78,810,596 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4623:Heatr5b
|
UTSW |
17 |
78,795,119 (GRCm38) |
missense |
possibly damaging |
0.52 |
|
R4654:Heatr5b
|
UTSW |
17 |
78,820,701 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R4939:Heatr5b
|
UTSW |
17 |
78,762,260 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4960:Heatr5b
|
UTSW |
17 |
78,831,584 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5037:Heatr5b
|
UTSW |
17 |
78,824,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5051:Heatr5b
|
UTSW |
17 |
78,795,274 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5153:Heatr5b
|
UTSW |
17 |
78,795,107 (GRCm38) |
nonsense |
probably null |
|
|
R5328:Heatr5b
|
UTSW |
17 |
78,826,362 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5346:Heatr5b
|
UTSW |
17 |
78,827,986 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5426:Heatr5b
|
UTSW |
17 |
78,773,713 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5470:Heatr5b
|
UTSW |
17 |
78,821,579 (GRCm38) |
splice site |
probably null |
|
|
R5472:Heatr5b
|
UTSW |
17 |
78,801,660 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5553:Heatr5b
|
UTSW |
17 |
78,753,351 (GRCm38) |
splice site |
probably null |
|
|
R5706:Heatr5b
|
UTSW |
17 |
78,766,875 (GRCm38) |
splice site |
probably null |
|
|
R5804:Heatr5b
|
UTSW |
17 |
78,831,522 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5978:Heatr5b
|
UTSW |
17 |
78,806,036 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6122:Heatr5b
|
UTSW |
17 |
78,813,173 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R6153:Heatr5b
|
UTSW |
17 |
78,831,441 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R6220:Heatr5b
|
UTSW |
17 |
78,773,677 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6221:Heatr5b
|
UTSW |
17 |
78,766,954 (GRCm38) |
missense |
probably benign |
0.05 |
|
R6255:Heatr5b
|
UTSW |
17 |
78,803,434 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6291:Heatr5b
|
UTSW |
17 |
78,762,097 (GRCm38) |
missense |
probably benign |
0.08 |
|
R6455:Heatr5b
|
UTSW |
17 |
78,753,073 (GRCm38) |
missense |
probably benign |
0.37 |
|
R6524:Heatr5b
|
UTSW |
17 |
78,814,106 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R6575:Heatr5b
|
UTSW |
17 |
78,762,989 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6899:Heatr5b
|
UTSW |
17 |
78,803,509 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7084:Heatr5b
|
UTSW |
17 |
78,810,563 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R7138:Heatr5b
|
UTSW |
17 |
78,827,988 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7148:Heatr5b
|
UTSW |
17 |
78,831,434 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7382:Heatr5b
|
UTSW |
17 |
78,803,507 (GRCm38) |
missense |
possibly damaging |
0.64 |
|
R7420:Heatr5b
|
UTSW |
17 |
78,808,480 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7436:Heatr5b
|
UTSW |
17 |
78,768,533 (GRCm38) |
missense |
probably benign |
|
|
R7519:Heatr5b
|
UTSW |
17 |
78,755,217 (GRCm38) |
missense |
probably benign |
|
|
R7606:Heatr5b
|
UTSW |
17 |
78,763,026 (GRCm38) |
missense |
probably benign |
|
|
R7673:Heatr5b
|
UTSW |
17 |
78,795,983 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R7782:Heatr5b
|
UTSW |
17 |
78,795,941 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7790:Heatr5b
|
UTSW |
17 |
78,818,823 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7922:Heatr5b
|
UTSW |
17 |
78,760,559 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8184:Heatr5b
|
UTSW |
17 |
78,814,233 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8222:Heatr5b
|
UTSW |
17 |
78,801,701 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8276:Heatr5b
|
UTSW |
17 |
78,791,539 (GRCm38) |
nonsense |
probably null |
|
|
R8324:Heatr5b
|
UTSW |
17 |
78,755,364 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R8430:Heatr5b
|
UTSW |
17 |
78,829,624 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8432:Heatr5b
|
UTSW |
17 |
78,803,501 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8672:Heatr5b
|
UTSW |
17 |
78,762,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8781:Heatr5b
|
UTSW |
17 |
78,795,309 (GRCm38) |
missense |
probably benign |
0.19 |
|
R8794:Heatr5b
|
UTSW |
17 |
78,815,586 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8808:Heatr5b
|
UTSW |
17 |
78,765,405 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R8850:Heatr5b
|
UTSW |
17 |
78,801,759 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8893:Heatr5b
|
UTSW |
17 |
78,761,995 (GRCm38) |
splice site |
probably benign |
|
|
R9010:Heatr5b
|
UTSW |
17 |
78,773,710 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9041:Heatr5b
|
UTSW |
17 |
78,796,432 (GRCm38) |
missense |
probably benign |
0.12 |
|
R9150:Heatr5b
|
UTSW |
17 |
78,796,019 (GRCm38) |
missense |
probably benign |
|
|
R9253:Heatr5b
|
UTSW |
17 |
78,827,994 (GRCm38) |
missense |
probably benign |
0.13 |
|
R9318:Heatr5b
|
UTSW |
17 |
78,765,402 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9448:Heatr5b
|
UTSW |
17 |
78,760,586 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9489:Heatr5b
|
UTSW |
17 |
78,753,250 (GRCm38) |
nonsense |
probably null |
|
|
R9649:Heatr5b
|
UTSW |
17 |
78,834,095 (GRCm38) |
critical splice donor site |
probably null |
|
|
X0022:Heatr5b
|
UTSW |
17 |
78,760,545 (GRCm38) |
missense |
probably benign |
0.38 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCCAGCAGTGAGTAAATGTGG -3'
(R):5'- ATATGAGGACAGCCATCCCG -3'
Sequencing Primer
(F):5'- CAGCAGTGAGTAAATGTGGACACC -3'
(R):5'- CAGTTGCTCTGTACACAGTAAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation