Incidental Mutation 'R1839:Ppp1r12b'
| ID |
205563 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ppp1r12b
|
| Ensembl Gene |
ENSMUSG00000073557 |
| Gene Name |
protein phosphatase 1, regulatory subunit 12B |
| Synonyms |
1810037O03Rik, 9530009M10Rik |
| MMRRC Submission |
045015-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.265)
|
| Stock # |
R1839 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
134682396-134883680 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 134765719 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 667
(R667G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000047463
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045665]
[ENSMUST00000086444]
[ENSMUST00000168381]
|
| AlphaFold |
Q8BG95 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045665
AA Change: R667G
PolyPhen 2
Score 0.325 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000047463
Gene: ENSMUSG00000073557
AA Change: R667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
27 |
N/A |
INTRINSIC |
|
ANK
|
56 |
86 |
8.36e1 |
SMART |
|
ANK
|
90 |
119 |
5.32e-5 |
SMART |
|
ANK
|
123 |
152 |
1.08e-5 |
SMART |
|
ANK
|
216 |
245 |
1.51e-4 |
SMART |
|
ANK
|
249 |
278 |
3.85e-2 |
SMART |
|
low complexity region
|
351 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
423 |
N/A |
INTRINSIC |
|
low complexity region
|
465 |
477 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
539 |
576 |
2.45e-5 |
PROSPERO |
|
PDB:2KJY|A
|
608 |
663 |
3e-12 |
PDB |
|
internal_repeat_3
|
729 |
766 |
2.45e-5 |
PROSPERO |
|
low complexity region
|
790 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
840 |
864 |
N/A |
INTRINSIC |
|
coiled coil region
|
867 |
974 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000086444
AA Change: R667G
PolyPhen 2
Score 0.115 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000083633
Gene: ENSMUSG00000073557
AA Change: R667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
27 |
N/A |
INTRINSIC |
|
ANK
|
56 |
86 |
8.36e1 |
SMART |
|
ANK
|
90 |
119 |
5.32e-5 |
SMART |
|
ANK
|
123 |
152 |
1.08e-5 |
SMART |
|
ANK
|
216 |
245 |
1.51e-4 |
SMART |
|
ANK
|
249 |
278 |
3.85e-2 |
SMART |
|
low complexity region
|
351 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
423 |
N/A |
INTRINSIC |
|
low complexity region
|
465 |
477 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
539 |
576 |
1.9e-5 |
PROSPERO |
|
PDB:2KJY|A
|
608 |
663 |
3e-12 |
PDB |
|
internal_repeat_3
|
729 |
766 |
1.9e-5 |
PROSPERO |
|
low complexity region
|
790 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
840 |
864 |
N/A |
INTRINSIC |
|
Pfam:PRKG1_interact
|
875 |
982 |
4.6e-31 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132025
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146639
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156348
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168381
AA Change: R667G
PolyPhen 2
Score 0.115 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000131406
Gene: ENSMUSG00000073557
AA Change: R667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
27 |
N/A |
INTRINSIC |
|
ANK
|
56 |
86 |
8.36e1 |
SMART |
|
ANK
|
90 |
119 |
5.32e-5 |
SMART |
|
ANK
|
123 |
152 |
1.08e-5 |
SMART |
|
ANK
|
216 |
245 |
1.51e-4 |
SMART |
|
ANK
|
249 |
278 |
3.85e-2 |
SMART |
|
low complexity region
|
351 |
379 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
423 |
N/A |
INTRINSIC |
|
low complexity region
|
465 |
477 |
N/A |
INTRINSIC |
|
internal_repeat_3
|
539 |
576 |
1.9e-5 |
PROSPERO |
|
PDB:2KJY|A
|
608 |
663 |
3e-12 |
PDB |
|
internal_repeat_3
|
729 |
766 |
1.9e-5 |
PROSPERO |
|
low complexity region
|
790 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
840 |
864 |
N/A |
INTRINSIC |
|
coiled coil region
|
867 |
986 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000188123
|
| Meta Mutation Damage Score |
0.1001 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.7%
- 10x: 94.7%
- 20x: 90.6%
|
| Validation Efficiency |
98% (90/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700006A11Rik |
T |
C |
3: 124,203,369 (GRCm39) |
T403A |
probably damaging |
Het |
| Acat3 |
T |
A |
17: 13,147,493 (GRCm39) |
R175* |
probably null |
Het |
| Adam1b |
C |
A |
5: 121,639,104 (GRCm39) |
C647F |
probably damaging |
Het |
| Adam28 |
T |
C |
14: 68,876,659 (GRCm39) |
N197S |
possibly damaging |
Het |
| Adcy2 |
C |
T |
13: 68,837,380 (GRCm39) |
|
probably null |
Het |
| Adcy5 |
A |
T |
16: 35,069,310 (GRCm39) |
N426I |
probably damaging |
Het |
| Adgre1 |
T |
C |
17: 57,748,299 (GRCm39) |
S500P |
probably benign |
Het |
| Aloxe3 |
A |
G |
11: 69,020,911 (GRCm39) |
Y212C |
probably damaging |
Het |
| Ap3d1 |
A |
G |
10: 80,562,942 (GRCm39) |
S180P |
probably damaging |
Het |
| Arhgap20 |
C |
T |
9: 51,760,626 (GRCm39) |
R790W |
probably damaging |
Het |
| Atp8b4 |
C |
A |
2: 126,203,702 (GRCm39) |
A757S |
possibly damaging |
Het |
| Begain |
G |
A |
12: 109,001,249 (GRCm39) |
|
probably benign |
Het |
| Ccdc141 |
T |
C |
2: 76,842,009 (GRCm39) |
E1474G |
probably benign |
Het |
| Ccdc88b |
A |
G |
19: 6,831,477 (GRCm39) |
|
probably benign |
Het |
| Ccnk |
A |
G |
12: 108,161,333 (GRCm39) |
T195A |
probably damaging |
Het |
| Cd55b |
C |
A |
1: 130,341,842 (GRCm39) |
C265F |
probably damaging |
Het |
| Celsr3 |
A |
G |
9: 108,707,105 (GRCm39) |
H1196R |
probably benign |
Het |
| Cenpt |
T |
C |
8: 106,575,646 (GRCm39) |
S190G |
possibly damaging |
Het |
| Chd8 |
T |
C |
14: 52,442,340 (GRCm39) |
S2077G |
probably benign |
Het |
| Col6a5 |
G |
A |
9: 105,742,032 (GRCm39) |
H2296Y |
probably benign |
Het |
| Cxxc4 |
C |
A |
3: 133,946,414 (GRCm39) |
H332N |
probably damaging |
Het |
| Cyp24a1 |
T |
C |
2: 170,338,661 (GRCm39) |
I12V |
probably benign |
Het |
| Cyp3a57 |
T |
A |
5: 145,318,111 (GRCm39) |
L364Q |
probably damaging |
Het |
| Ddi2 |
T |
C |
4: 141,440,837 (GRCm39) |
I47V |
probably benign |
Het |
| Ddx5 |
A |
T |
11: 106,675,723 (GRCm39) |
D322E |
probably benign |
Het |
| Dhx40 |
A |
G |
11: 86,680,123 (GRCm39) |
C405R |
possibly damaging |
Het |
| Emc1 |
T |
C |
4: 139,087,796 (GRCm39) |
F100S |
probably damaging |
Het |
| Exoc2 |
T |
C |
13: 31,090,480 (GRCm39) |
|
probably benign |
Het |
| Gm10110 |
A |
T |
14: 90,135,272 (GRCm39) |
|
noncoding transcript |
Het |
| Gm17332 |
T |
C |
11: 31,132,386 (GRCm39) |
H26R |
possibly damaging |
Het |
| Gna12 |
T |
C |
5: 140,748,367 (GRCm39) |
N183S |
probably benign |
Het |
| Gpx6 |
A |
G |
13: 21,496,497 (GRCm39) |
N24D |
probably benign |
Het |
| Gsdma3 |
C |
T |
11: 98,520,684 (GRCm39) |
A105V |
probably benign |
Het |
| Hsd3b5 |
T |
C |
3: 98,527,044 (GRCm39) |
Y134C |
probably benign |
Het |
| Ifi213 |
T |
C |
1: 173,417,166 (GRCm39) |
I415M |
probably damaging |
Het |
| Ints9 |
C |
A |
14: 65,253,979 (GRCm39) |
P278T |
probably damaging |
Het |
| Krt79 |
C |
T |
15: 101,846,373 (GRCm39) |
E192K |
possibly damaging |
Het |
| Lrrk2 |
A |
G |
15: 91,567,337 (GRCm39) |
N132S |
probably benign |
Het |
| Ltn1 |
T |
A |
16: 87,213,152 (GRCm39) |
K470* |
probably null |
Het |
| Magi2 |
A |
T |
5: 20,670,825 (GRCm39) |
T163S |
probably damaging |
Het |
| Mcm9 |
A |
G |
10: 53,417,649 (GRCm39) |
M18T |
probably damaging |
Het |
| Med12l |
A |
G |
3: 58,975,740 (GRCm39) |
T212A |
probably benign |
Het |
| Mfhas1 |
T |
C |
8: 36,058,012 (GRCm39) |
L829P |
possibly damaging |
Het |
| Mgme1 |
T |
A |
2: 144,121,407 (GRCm39) |
C288S |
probably benign |
Het |
| Muc4 |
G |
C |
16: 32,753,919 (GRCm38) |
R1265P |
probably benign |
Het |
| Myh7 |
T |
C |
14: 55,210,637 (GRCm39) |
N1725S |
possibly damaging |
Het |
| Naa80 |
G |
A |
9: 107,460,216 (GRCm39) |
R37H |
possibly damaging |
Het |
| Nme4 |
A |
T |
17: 26,311,071 (GRCm39) |
W165R |
probably damaging |
Het |
| Nup205 |
T |
A |
6: 35,196,649 (GRCm39) |
D1128E |
probably benign |
Het |
| Or2t48 |
A |
T |
11: 58,420,199 (GRCm39) |
Y204* |
probably null |
Het |
| Or5ae2 |
T |
C |
7: 84,505,756 (GRCm39) |
Y60H |
probably damaging |
Het |
| Pcdh1 |
T |
C |
18: 38,332,538 (GRCm39) |
D155G |
possibly damaging |
Het |
| Pex12 |
A |
T |
11: 83,188,648 (GRCm39) |
S116T |
probably damaging |
Het |
| Plekhh1 |
C |
T |
12: 79,125,731 (GRCm39) |
|
probably benign |
Het |
| Plekhh3 |
A |
G |
11: 101,054,426 (GRCm39) |
|
probably benign |
Het |
| Pnpt1 |
T |
C |
11: 29,104,342 (GRCm39) |
M572T |
possibly damaging |
Het |
| Rbpms2 |
ACTGCTGCTGCTGCTGC |
ACTGCTGCTGCTGCTGCTGC |
9: 65,558,948 (GRCm39) |
|
probably benign |
Het |
| Rgs14 |
T |
C |
13: 55,530,651 (GRCm39) |
|
probably benign |
Het |
| Rhbdf2 |
A |
T |
11: 116,491,017 (GRCm39) |
V645E |
possibly damaging |
Het |
| Robo3 |
A |
G |
9: 37,333,623 (GRCm39) |
V696A |
probably benign |
Het |
| Sall1 |
A |
G |
8: 89,755,344 (GRCm39) |
F1212L |
possibly damaging |
Het |
| Sdc4 |
T |
C |
2: 164,270,932 (GRCm39) |
E109G |
probably benign |
Het |
| Serpind1 |
G |
T |
16: 17,160,856 (GRCm39) |
R462L |
probably damaging |
Het |
| Smad9 |
CTTT |
CTT |
3: 54,696,600 (GRCm39) |
|
probably benign |
Het |
| Sstr4 |
C |
A |
2: 148,237,453 (GRCm39) |
N21K |
probably benign |
Het |
| Tap1 |
C |
T |
17: 34,407,083 (GRCm39) |
A77V |
possibly damaging |
Het |
| Thap4 |
T |
C |
1: 93,678,009 (GRCm39) |
E259G |
probably benign |
Het |
| Thra |
A |
G |
11: 98,646,969 (GRCm39) |
N30S |
probably benign |
Het |
| Tmem207 |
A |
T |
16: 26,343,571 (GRCm39) |
V27E |
possibly damaging |
Het |
| Top3a |
A |
G |
11: 60,644,714 (GRCm39) |
V305A |
probably damaging |
Het |
| Trim59 |
A |
T |
3: 68,944,971 (GRCm39) |
I123K |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,691,839 (GRCm39) |
|
probably benign |
Het |
| Ubac1 |
T |
A |
2: 25,897,750 (GRCm39) |
E290V |
possibly damaging |
Het |
| Unc13b |
T |
C |
4: 43,258,308 (GRCm39) |
|
probably benign |
Het |
| Uri1 |
A |
T |
7: 37,666,814 (GRCm39) |
D206E |
probably benign |
Het |
| Utp4 |
A |
G |
8: 107,640,086 (GRCm39) |
H465R |
probably benign |
Het |
| Uvssa |
T |
C |
5: 33,547,096 (GRCm39) |
S221P |
probably benign |
Het |
| Vmn1r39 |
T |
C |
6: 66,782,217 (GRCm39) |
|
probably null |
Het |
| Vps39 |
A |
T |
2: 120,155,878 (GRCm39) |
L514H |
probably damaging |
Het |
| Vps72 |
G |
A |
3: 95,026,529 (GRCm39) |
R158Q |
possibly damaging |
Het |
| Wdr59 |
T |
C |
8: 112,211,972 (GRCm39) |
D366G |
probably benign |
Het |
| Zfp366 |
C |
A |
13: 99,365,000 (GRCm39) |
Q54K |
probably damaging |
Het |
| Zfp523 |
T |
A |
17: 28,413,967 (GRCm39) |
I34N |
probably damaging |
Het |
| Zfp974 |
G |
A |
7: 27,609,781 (GRCm39) |
P648L |
possibly damaging |
Het |
|
| Other mutations in Ppp1r12b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01358:Ppp1r12b
|
APN |
1 |
134,819,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01788:Ppp1r12b
|
APN |
1 |
134,821,245 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL01880:Ppp1r12b
|
APN |
1 |
134,814,159 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02109:Ppp1r12b
|
APN |
1 |
134,800,543 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02247:Ppp1r12b
|
APN |
1 |
134,763,721 (GRCm39) |
missense |
probably benign |
|
|
IGL02336:Ppp1r12b
|
APN |
1 |
134,814,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02903:Ppp1r12b
|
APN |
1 |
134,883,387 (GRCm39) |
missense |
probably benign |
|
|
IGL02963:Ppp1r12b
|
APN |
1 |
134,814,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03074:Ppp1r12b
|
APN |
1 |
134,763,758 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03302:Ppp1r12b
|
APN |
1 |
134,765,788 (GRCm39) |
splice site |
probably benign |
|
|
R0102:Ppp1r12b
|
UTSW |
1 |
134,763,637 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0102:Ppp1r12b
|
UTSW |
1 |
134,763,637 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0189:Ppp1r12b
|
UTSW |
1 |
134,793,514 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0556:Ppp1r12b
|
UTSW |
1 |
134,705,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Ppp1r12b
|
UTSW |
1 |
134,704,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0690:Ppp1r12b
|
UTSW |
1 |
134,803,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1354:Ppp1r12b
|
UTSW |
1 |
134,763,721 (GRCm39) |
missense |
probably benign |
0.42 |
|
R1676:Ppp1r12b
|
UTSW |
1 |
134,705,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1775:Ppp1r12b
|
UTSW |
1 |
134,821,086 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1946:Ppp1r12b
|
UTSW |
1 |
134,820,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Ppp1r12b
|
UTSW |
1 |
134,793,651 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1997:Ppp1r12b
|
UTSW |
1 |
134,774,093 (GRCm39) |
intron |
probably benign |
|
|
R3110:Ppp1r12b
|
UTSW |
1 |
134,800,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3112:Ppp1r12b
|
UTSW |
1 |
134,800,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3908:Ppp1r12b
|
UTSW |
1 |
134,770,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3912:Ppp1r12b
|
UTSW |
1 |
134,815,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3977:Ppp1r12b
|
UTSW |
1 |
134,693,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4243:Ppp1r12b
|
UTSW |
1 |
134,709,846 (GRCm39) |
intron |
probably benign |
|
|
R4835:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4836:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4843:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4854:Ppp1r12b
|
UTSW |
1 |
134,801,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4870:Ppp1r12b
|
UTSW |
1 |
134,876,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4881:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5024:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5054:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5055:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5056:Ppp1r12b
|
UTSW |
1 |
134,883,471 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5056:Ppp1r12b
|
UTSW |
1 |
134,762,130 (GRCm39) |
intron |
probably benign |
|
|
R5158:Ppp1r12b
|
UTSW |
1 |
134,814,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5599:Ppp1r12b
|
UTSW |
1 |
134,793,645 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5771:Ppp1r12b
|
UTSW |
1 |
134,701,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5775:Ppp1r12b
|
UTSW |
1 |
134,803,780 (GRCm39) |
missense |
probably benign |
|
|
R5872:Ppp1r12b
|
UTSW |
1 |
134,704,144 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5896:Ppp1r12b
|
UTSW |
1 |
134,693,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6060:Ppp1r12b
|
UTSW |
1 |
134,883,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6129:Ppp1r12b
|
UTSW |
1 |
134,819,990 (GRCm39) |
nonsense |
probably null |
|
|
R6369:Ppp1r12b
|
UTSW |
1 |
134,814,280 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6868:Ppp1r12b
|
UTSW |
1 |
134,814,176 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7681:Ppp1r12b
|
UTSW |
1 |
134,793,673 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7940:Ppp1r12b
|
UTSW |
1 |
134,803,793 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8057:Ppp1r12b
|
UTSW |
1 |
134,883,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ppp1r12b
|
UTSW |
1 |
134,803,807 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8134:Ppp1r12b
|
UTSW |
1 |
134,814,280 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8147:Ppp1r12b
|
UTSW |
1 |
134,801,680 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8224:Ppp1r12b
|
UTSW |
1 |
134,830,200 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8270:Ppp1r12b
|
UTSW |
1 |
134,803,886 (GRCm39) |
missense |
probably benign |
0.37 |
|
R8304:Ppp1r12b
|
UTSW |
1 |
134,824,101 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8803:Ppp1r12b
|
UTSW |
1 |
134,818,492 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R8826:Ppp1r12b
|
UTSW |
1 |
134,693,730 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8954:Ppp1r12b
|
UTSW |
1 |
134,762,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9081:Ppp1r12b
|
UTSW |
1 |
134,705,085 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9171:Ppp1r12b
|
UTSW |
1 |
134,801,725 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9223:Ppp1r12b
|
UTSW |
1 |
134,807,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9521:Ppp1r12b
|
UTSW |
1 |
134,705,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9609:Ppp1r12b
|
UTSW |
1 |
134,824,084 (GRCm39) |
nonsense |
probably null |
|
|
X0022:Ppp1r12b
|
UTSW |
1 |
134,763,611 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0027:Ppp1r12b
|
UTSW |
1 |
134,824,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1187:Ppp1r12b
|
UTSW |
1 |
134,883,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1189:Ppp1r12b
|
UTSW |
1 |
134,883,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1190:Ppp1r12b
|
UTSW |
1 |
134,883,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1192:Ppp1r12b
|
UTSW |
1 |
134,883,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCACTTCAAGGCAGGATAGC -3'
(R):5'- ATGTGTTGCTAGAAATGGCCTG -3'
Sequencing Primer
(F):5'- GCAGGATAGCATTTAAGTCACC -3'
(R):5'- CTAGAAATGGCCTGTTGGGAG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation