Incidental Mutation 'R1840:Ddx60'
| ID |
205705 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| Synonyms |
|
| MMRRC Submission |
039866-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.145)
|
| Stock # |
R1840 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
61928087-62038244 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 61969553 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Asparagine
at position 608
(I608N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000070631
AA Change: I607N
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: I607N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000093485
AA Change: I608N
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: I608N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 118 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700029I15Rik |
T |
C |
2: 92,383,209 (GRCm38) |
S36P |
probably benign |
Het |
| 2510009E07Rik |
T |
A |
16: 21,653,486 (GRCm38) |
M85L |
probably benign |
Het |
| Aatk |
T |
G |
11: 120,013,732 (GRCm38) |
D206A |
probably damaging |
Het |
| Agap3 |
A |
G |
5: 24,500,231 (GRCm38) |
D719G |
probably damaging |
Het |
| Agrn |
G |
A |
4: 156,167,415 (GRCm38) |
R1797C |
probably damaging |
Het |
| Ascc3 |
T |
A |
10: 50,690,161 (GRCm38) |
M734K |
probably benign |
Het |
| Asph |
T |
A |
4: 9,601,340 (GRCm38) |
M136L |
possibly damaging |
Het |
| Atm |
A |
T |
9: 53,456,530 (GRCm38) |
V2431E |
probably damaging |
Het |
| Atp2b1 |
A |
G |
10: 99,022,929 (GRCm38) |
H1158R |
probably benign |
Het |
| Atxn7l1 |
A |
G |
12: 33,371,033 (GRCm38) |
|
probably null |
Het |
| BC024139 |
G |
T |
15: 76,120,642 (GRCm38) |
S611R |
probably benign |
Het |
| Becn1 |
C |
T |
11: 101,295,566 (GRCm38) |
G105S |
probably damaging |
Het |
| Bud13 |
A |
G |
9: 46,286,408 (GRCm38) |
E70G |
probably damaging |
Het |
| Cacul1 |
A |
T |
19: 60,534,250 (GRCm38) |
L282* |
probably null |
Het |
| Ccar1 |
T |
A |
10: 62,763,510 (GRCm38) |
K614M |
probably damaging |
Het |
| Cd96 |
T |
C |
16: 46,099,092 (GRCm38) |
T189A |
probably benign |
Het |
| Cdh5 |
C |
A |
8: 104,126,616 (GRCm38) |
Y189* |
probably null |
Het |
| Chka |
A |
G |
19: 3,886,460 (GRCm38) |
N284S |
probably benign |
Het |
| Cntn6 |
A |
T |
6: 104,774,480 (GRCm38) |
I366F |
probably damaging |
Het |
| Csmd3 |
C |
T |
15: 47,607,164 (GRCm38) |
G3372E |
probably damaging |
Het |
| Cyp4f16 |
T |
C |
17: 32,543,006 (GRCm38) |
|
probably null |
Het |
| Dcaf6 |
A |
G |
1: 165,399,748 (GRCm38) |
V270A |
probably damaging |
Het |
| Dnah9 |
A |
T |
11: 65,834,198 (GRCm38) |
C1849* |
probably null |
Het |
| Eci3 |
C |
A |
13: 34,960,041 (GRCm38) |
V34L |
probably benign |
Het |
| Epha1 |
C |
T |
6: 42,363,588 (GRCm38) |
R583H |
probably damaging |
Het |
| Erbin |
A |
T |
13: 103,834,947 (GRCm38) |
N720K |
probably benign |
Het |
| Eya1 |
T |
A |
1: 14,229,504 (GRCm38) |
R346* |
probably null |
Het |
| Fam189a1 |
C |
A |
7: 64,759,195 (GRCm38) |
V484L |
probably benign |
Het |
| Fhdc1 |
G |
A |
3: 84,445,821 (GRCm38) |
T699I |
possibly damaging |
Het |
| Flvcr2 |
T |
C |
12: 85,803,221 (GRCm38) |
V427A |
possibly damaging |
Het |
| Fzd9 |
T |
A |
5: 135,249,571 (GRCm38) |
T487S |
probably benign |
Het |
| Gas2l3 |
T |
C |
10: 89,422,251 (GRCm38) |
Y160C |
possibly damaging |
Het |
| Gm10264 |
T |
C |
12: 88,329,411 (GRCm38) |
V53A |
probably benign |
Het |
| Gm10269 |
T |
C |
18: 20,682,809 (GRCm38) |
K52R |
probably damaging |
Het |
| Gm16432 |
A |
G |
1: 178,003,015 (GRCm38) |
D30G |
possibly damaging |
Het |
| Gm8674 |
A |
T |
13: 49,901,765 (GRCm38) |
|
noncoding transcript |
Het |
| Gpr61 |
A |
G |
3: 108,150,481 (GRCm38) |
V288A |
possibly damaging |
Het |
| Gramd4 |
T |
C |
15: 86,130,192 (GRCm38) |
|
probably null |
Het |
| Gtpbp4 |
A |
G |
13: 8,979,464 (GRCm38) |
L403P |
probably benign |
Het |
| H6pd |
A |
T |
4: 149,982,050 (GRCm38) |
D626E |
possibly damaging |
Het |
| Herc6 |
T |
A |
6: 57,658,106 (GRCm38) |
L769* |
probably null |
Het |
| Hes5 |
A |
G |
4: 154,961,254 (GRCm38) |
K58R |
probably damaging |
Het |
| Heyl |
A |
G |
4: 123,241,390 (GRCm38) |
I59V |
probably damaging |
Het |
| Hpca |
A |
G |
4: 129,118,600 (GRCm38) |
F48L |
probably damaging |
Het |
| Ice1 |
C |
T |
13: 70,606,218 (GRCm38) |
R583Q |
probably benign |
Het |
| Ints2 |
C |
T |
11: 86,233,085 (GRCm38) |
G626R |
probably damaging |
Het |
| Kansl1l |
T |
A |
1: 66,778,032 (GRCm38) |
I390F |
probably damaging |
Het |
| Kat5 |
C |
T |
19: 5,609,238 (GRCm38) |
V95M |
possibly damaging |
Het |
| Kcnh4 |
T |
A |
11: 100,745,341 (GRCm38) |
I827F |
possibly damaging |
Het |
| Kif1b |
C |
T |
4: 149,188,132 (GRCm38) |
R138Q |
probably damaging |
Het |
| Kirrel |
C |
T |
3: 87,089,151 (GRCm38) |
M380I |
probably null |
Het |
| Lats1 |
T |
A |
10: 7,710,939 (GRCm38) |
L955* |
probably null |
Het |
| Ldlrad2 |
A |
C |
4: 137,572,184 (GRCm38) |
C110G |
possibly damaging |
Het |
| Lgi3 |
G |
A |
14: 70,534,776 (GRCm38) |
|
probably null |
Het |
| Lingo1 |
A |
G |
9: 56,620,558 (GRCm38) |
M249T |
probably benign |
Het |
| Lrig3 |
A |
T |
10: 126,013,389 (GRCm38) |
R993* |
probably null |
Het |
| Lsm14b |
T |
A |
2: 180,026,728 (GRCm38) |
I74N |
probably damaging |
Het |
| Lyplal1 |
T |
A |
1: 186,100,217 (GRCm38) |
I114F |
probably damaging |
Het |
| Mmp15 |
A |
G |
8: 95,365,420 (GRCm38) |
Y86C |
probably damaging |
Het |
| Myh2 |
A |
G |
11: 67,186,487 (GRCm38) |
E816G |
probably benign |
Het |
| Myo5c |
A |
G |
9: 75,249,735 (GRCm38) |
N151S |
probably damaging |
Het |
| Nckap1 |
T |
A |
2: 80,502,250 (GRCm38) |
E1082V |
possibly damaging |
Het |
| Nrg4 |
A |
C |
9: 55,282,606 (GRCm38) |
|
probably benign |
Het |
| Nrp2 |
T |
C |
1: 62,738,339 (GRCm38) |
L101P |
probably damaging |
Het |
| Olfr1180 |
T |
C |
2: 88,412,067 (GRCm38) |
D197G |
probably benign |
Het |
| Olfr126 |
A |
T |
17: 37,850,748 (GRCm38) |
D52V |
probably damaging |
Het |
| Olfr521 |
A |
T |
7: 99,767,596 (GRCm38) |
T145S |
probably benign |
Het |
| Olfr638 |
A |
G |
7: 104,004,117 (GRCm38) |
I281V |
probably benign |
Het |
| Olfr992 |
G |
A |
2: 85,400,168 (GRCm38) |
R122C |
probably benign |
Het |
| Parp14 |
T |
A |
16: 35,863,449 (GRCm38) |
E169V |
probably damaging |
Het |
| Pcolce2 |
G |
A |
9: 95,670,117 (GRCm38) |
R101H |
probably damaging |
Het |
| Pcolce2 |
A |
T |
9: 95,670,203 (GRCm38) |
N130Y |
probably benign |
Het |
| Plscr1 |
A |
T |
9: 92,258,074 (GRCm38) |
S5C |
unknown |
Het |
| Plxdc2 |
T |
C |
2: 16,669,856 (GRCm38) |
V338A |
probably benign |
Het |
| Psg23 |
T |
A |
7: 18,610,438 (GRCm38) |
N364I |
possibly damaging |
Het |
| Psmg4 |
A |
G |
13: 34,178,056 (GRCm38) |
E109G |
probably damaging |
Het |
| Ptk2 |
T |
C |
15: 73,210,884 (GRCm38) |
E908G |
probably damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,786,851 (GRCm38) |
R26H |
probably damaging |
Het |
| Ranbp2 |
T |
A |
10: 58,478,766 (GRCm38) |
N1769K |
probably benign |
Het |
| Rbm14 |
C |
T |
19: 4,801,795 (GRCm38) |
|
probably benign |
Het |
| Rgs7 |
A |
T |
1: 175,153,148 (GRCm38) |
D103E |
probably damaging |
Het |
| Rmnd5a |
G |
A |
6: 71,398,455 (GRCm38) |
L80F |
probably benign |
Het |
| Rock2 |
T |
A |
12: 16,928,989 (GRCm38) |
D93E |
probably benign |
Het |
| Rps6ka6 |
A |
G |
X: 111,420,932 (GRCm38) |
I246T |
possibly damaging |
Het |
| Rubcn |
T |
C |
16: 32,826,172 (GRCm38) |
M803V |
possibly damaging |
Het |
| Ryr3 |
T |
C |
2: 112,750,820 (GRCm38) |
Y2889C |
probably damaging |
Het |
| Sall2 |
T |
C |
14: 52,313,725 (GRCm38) |
N671S |
probably damaging |
Het |
| Selplg |
T |
C |
5: 113,819,844 (GRCm38) |
T134A |
possibly damaging |
Het |
| Sez6 |
C |
A |
11: 77,953,717 (GRCm38) |
T122N |
possibly damaging |
Het |
| Slc9b1 |
T |
A |
3: 135,357,468 (GRCm38) |
D4E |
unknown |
Het |
| Smim18 |
A |
G |
8: 33,742,348 (GRCm38) |
M81T |
probably benign |
Het |
| Snap91 |
A |
T |
9: 86,815,465 (GRCm38) |
H281Q |
probably damaging |
Het |
| Sparc |
C |
A |
11: 55,395,866 (GRCm38) |
C302F |
probably damaging |
Het |
| Spg11 |
A |
G |
2: 122,101,756 (GRCm38) |
L535P |
probably damaging |
Het |
| Spsb1 |
G |
A |
4: 149,906,631 (GRCm38) |
T160I |
probably damaging |
Het |
| Stra6 |
A |
G |
9: 58,140,530 (GRCm38) |
N128S |
probably benign |
Het |
| Strc |
T |
C |
2: 121,379,296 (GRCm38) |
E182G |
probably damaging |
Het |
| Sult2a6 |
A |
G |
7: 14,254,829 (GRCm38) |
M2T |
probably benign |
Het |
| Sv2c |
T |
C |
13: 95,981,844 (GRCm38) |
N499S |
probably benign |
Het |
| Szt2 |
A |
T |
4: 118,365,657 (GRCm38) |
|
probably benign |
Het |
| Tbx20 |
A |
T |
9: 24,725,676 (GRCm38) |
S372T |
probably benign |
Het |
| Tcp11l2 |
T |
A |
10: 84,604,599 (GRCm38) |
S289T |
probably damaging |
Het |
| Tdrd1 |
A |
G |
19: 56,842,312 (GRCm38) |
E259G |
probably damaging |
Het |
| Thsd7a |
T |
A |
6: 12,330,974 (GRCm38) |
I1390L |
probably benign |
Het |
| Tln2 |
G |
A |
9: 67,342,043 (GRCm38) |
R921W |
probably damaging |
Het |
| Tmem126a |
C |
A |
7: 90,452,884 (GRCm38) |
G36* |
probably null |
Het |
| Tmem245 |
C |
T |
4: 56,903,947 (GRCm38) |
V606I |
probably benign |
Het |
| Trpm6 |
A |
G |
19: 18,866,267 (GRCm38) |
D1665G |
probably benign |
Het |
| Ubac2 |
T |
G |
14: 121,994,262 (GRCm38) |
V200G |
probably benign |
Het |
| Ubr5 |
G |
A |
15: 37,980,917 (GRCm38) |
A2372V |
possibly damaging |
Het |
| Ugcg |
C |
T |
4: 59,219,517 (GRCm38) |
P285S |
probably damaging |
Het |
| Vmn1r9 |
T |
C |
6: 57,071,537 (GRCm38) |
V199A |
probably damaging |
Het |
| Vmn2r118 |
T |
A |
17: 55,610,406 (GRCm38) |
K369* |
probably null |
Het |
| Xpnpep3 |
G |
T |
15: 81,427,353 (GRCm38) |
A87S |
probably benign |
Het |
| Zc3h7a |
C |
T |
16: 11,161,026 (GRCm38) |
R95H |
probably damaging |
Het |
| Zdhhc11 |
A |
G |
13: 73,974,652 (GRCm38) |
N169S |
probably damaging |
Het |
| Zfp62 |
T |
A |
11: 49,216,388 (GRCm38) |
D435E |
probably damaging |
Het |
| Zfyve16 |
T |
C |
13: 92,511,525 (GRCm38) |
D1007G |
possibly damaging |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
61,958,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
61,987,431 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
61,969,583 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
61,942,514 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
61,982,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
61,963,740 (GRCm38) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
61,983,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,017,823 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,000,709 (GRCm38) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,017,247 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
61,975,832 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
61,958,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,024,951 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
61,942,436 (GRCm38) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
61,984,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
61,988,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
61,979,341 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
61,956,122 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
61,988,083 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,012,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
61,977,882 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
61,958,113 (GRCm38) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
61,972,254 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
61,942,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,033,493 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
61,983,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,017,749 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
61,994,541 (GRCm38) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
61,969,657 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,017,794 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
61,987,361 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
61,942,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
61,958,159 (GRCm38) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
61,974,176 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1964:Ddx60
|
UTSW |
8 |
61,948,869 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1970:Ddx60
|
UTSW |
8 |
61,972,206 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
61,940,645 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,017,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
61,956,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
61,958,063 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,037,091 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,012,436 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,037,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
61,956,144 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
61,972,220 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
61,994,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
61,948,978 (GRCm38) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
61,942,461 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
61,987,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,023,261 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,012,424 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
61,945,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
61,974,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
61,984,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,010,002 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
61,950,451 (GRCm38) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
61,958,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,000,578 (GRCm38) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
61,948,921 (GRCm38) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
61,948,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,012,388 (GRCm38) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
61,963,722 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
61,940,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,021,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,000,582 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,023,241 (GRCm38) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
61,945,940 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
61,950,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
61,983,905 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
61,998,681 (GRCm38) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
61,977,950 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
61,956,239 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
61,983,890 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,000,689 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,037,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
61,988,108 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
61,958,578 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
61,940,674 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
61,975,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
61,977,890 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,017,171 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,017,250 (GRCm38) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
61,977,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
61,998,769 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
61,942,635 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
61,974,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
61,956,243 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
61,974,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
61,958,606 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
61,945,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
61,940,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
61,994,519 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
61,974,134 (GRCm38) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
61,989,864 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,017,841 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
61,977,978 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,009,960 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
61,972,214 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,012,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,033,417 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
61,963,692 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,000,588 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCAGCAGGTCTTTATTTTCAC -3'
(R):5'- GGATTATGCACCACATACCTTCAG -3'
Sequencing Primer
(F):5'- AGCAGGTCTTTATTTTCACTGAGTTG -3'
(R):5'- ATACCTTCAGCCTGGCAATG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation