Incidental Mutation 'R1854:Anapc1'
| ID |
205887 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
039878-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1854 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 128517810 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 278
(E278G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105962
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
[ENSMUST00000110333]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000014499
AA Change: E278G
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: E278G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000110333
AA Change: E278G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000105962
Gene: ENSMUSG00000014355
AA Change: E278G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Apc1
|
149 |
227 |
1.7e-22 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134485
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310061N02Rik |
C |
T |
16: 88,504,668 (GRCm39) |
R43K |
possibly damaging |
Het |
| Acp1 |
A |
G |
12: 30,947,804 (GRCm39) |
I78T |
possibly damaging |
Het |
| Afap1l1 |
G |
T |
18: 61,876,365 (GRCm39) |
D417E |
probably benign |
Het |
| Agap2 |
G |
A |
10: 126,916,385 (GRCm39) |
V299I |
unknown |
Het |
| Ahnak |
C |
T |
19: 8,991,196 (GRCm39) |
A4160V |
possibly damaging |
Het |
| Atad2 |
G |
A |
15: 57,960,685 (GRCm39) |
P971L |
possibly damaging |
Het |
| Atg2a |
A |
G |
19: 6,302,461 (GRCm39) |
E928G |
probably benign |
Het |
| Atp2b2 |
A |
C |
6: 113,819,244 (GRCm39) |
N16K |
probably damaging |
Het |
| Atp6ap1l |
T |
C |
13: 91,031,707 (GRCm39) |
E325G |
probably damaging |
Het |
| Bfsp2 |
C |
T |
9: 103,327,030 (GRCm39) |
G236S |
probably benign |
Het |
| Ccar1 |
A |
T |
10: 62,600,296 (GRCm39) |
I545N |
probably damaging |
Het |
| Ccser2 |
A |
G |
14: 36,640,548 (GRCm39) |
C11R |
possibly damaging |
Het |
| Cdc42bpg |
A |
T |
19: 6,370,837 (GRCm39) |
H1310L |
possibly damaging |
Het |
| Ces1h |
T |
C |
8: 94,085,450 (GRCm39) |
K339E |
probably benign |
Het |
| Cfap91 |
T |
C |
16: 38,144,659 (GRCm39) |
|
probably null |
Het |
| Cit |
A |
G |
5: 116,011,960 (GRCm39) |
Y189C |
probably damaging |
Het |
| Cnih3 |
C |
A |
1: 181,282,186 (GRCm39) |
S140* |
probably null |
Het |
| Cntrl |
A |
G |
2: 35,012,696 (GRCm39) |
D278G |
probably damaging |
Het |
| Col24a1 |
G |
A |
3: 145,164,895 (GRCm39) |
G1033D |
probably damaging |
Het |
| Col6a1 |
T |
G |
10: 76,557,783 (GRCm39) |
Y151S |
probably damaging |
Het |
| Col6a2 |
T |
A |
10: 76,450,646 (GRCm39) |
Q95L |
probably damaging |
Het |
| Cpd |
G |
T |
11: 76,677,164 (GRCm39) |
P1185Q |
probably damaging |
Het |
| Cycs |
T |
A |
6: 50,542,309 (GRCm39) |
I76F |
possibly damaging |
Het |
| Cyp4f16 |
T |
A |
17: 32,756,073 (GRCm39) |
I34N |
probably damaging |
Het |
| Ddx1 |
A |
C |
12: 13,279,332 (GRCm39) |
S436A |
probably benign |
Het |
| Defa30 |
A |
G |
8: 21,625,500 (GRCm39) |
Y88C |
probably damaging |
Het |
| Dhx30 |
G |
A |
9: 109,917,740 (GRCm39) |
L317F |
probably damaging |
Het |
| Dll3 |
C |
A |
7: 27,995,835 (GRCm39) |
G322V |
probably damaging |
Het |
| Dnah10 |
G |
A |
5: 124,881,753 (GRCm39) |
D2843N |
probably damaging |
Het |
| Dnaja3 |
C |
T |
16: 4,515,133 (GRCm39) |
T266I |
probably damaging |
Het |
| Dpp9 |
T |
C |
17: 56,509,885 (GRCm39) |
I314V |
probably benign |
Het |
| E030025P04Rik |
A |
G |
11: 109,034,744 (GRCm39) |
V48A |
unknown |
Het |
| Enpp2 |
C |
T |
15: 54,709,219 (GRCm39) |
E803K |
probably damaging |
Het |
| Eri3 |
G |
A |
4: 117,506,562 (GRCm39) |
G297D |
probably benign |
Het |
| Esp34 |
A |
G |
17: 38,870,424 (GRCm39) |
E38G |
possibly damaging |
Het |
| Fabp3 |
C |
T |
4: 130,206,180 (GRCm39) |
T57I |
probably benign |
Het |
| Frzb |
A |
G |
2: 80,276,724 (GRCm39) |
V154A |
possibly damaging |
Het |
| Fsip2 |
G |
T |
2: 82,823,601 (GRCm39) |
A6445S |
possibly damaging |
Het |
| Gm11938 |
G |
A |
11: 99,493,843 (GRCm39) |
T84I |
possibly damaging |
Het |
| Gm4787 |
T |
A |
12: 81,425,108 (GRCm39) |
H350L |
probably damaging |
Het |
| Gpa33 |
A |
G |
1: 165,992,759 (GRCm39) |
I291V |
probably benign |
Het |
| Gpr158 |
A |
G |
2: 21,373,935 (GRCm39) |
Y290C |
probably damaging |
Het |
| Gpsm1 |
G |
T |
2: 26,234,725 (GRCm39) |
G84W |
probably damaging |
Het |
| Hormad1 |
A |
G |
3: 95,487,317 (GRCm39) |
N267S |
probably benign |
Het |
| Htr2a |
A |
T |
14: 74,943,193 (GRCm39) |
I258F |
probably damaging |
Het |
| Htra4 |
T |
C |
8: 25,523,597 (GRCm39) |
T323A |
probably damaging |
Het |
| Ift140 |
T |
A |
17: 25,254,813 (GRCm39) |
F162Y |
probably benign |
Het |
| Islr2 |
T |
C |
9: 58,107,099 (GRCm39) |
T54A |
probably damaging |
Het |
| Kcna4 |
T |
G |
2: 107,126,829 (GRCm39) |
V521G |
probably damaging |
Het |
| Kdr |
C |
T |
5: 76,113,565 (GRCm39) |
G768S |
possibly damaging |
Het |
| Kif6 |
G |
T |
17: 50,208,799 (GRCm39) |
A740S |
probably benign |
Het |
| Lad1 |
T |
A |
1: 135,755,468 (GRCm39) |
V248E |
probably damaging |
Het |
| Lamb1 |
T |
G |
12: 31,368,271 (GRCm39) |
C1134G |
probably damaging |
Het |
| Lamc1 |
A |
G |
1: 153,125,618 (GRCm39) |
Y552H |
probably damaging |
Het |
| Mctp1 |
A |
T |
13: 76,973,860 (GRCm39) |
T706S |
probably damaging |
Het |
| Med12l |
A |
G |
3: 59,168,193 (GRCm39) |
Y1541C |
probably damaging |
Het |
| Mnx1 |
C |
T |
5: 29,682,780 (GRCm39) |
S165N |
unknown |
Het |
| Morn3 |
A |
T |
5: 123,184,692 (GRCm39) |
|
probably null |
Het |
| Nalcn |
C |
T |
14: 123,697,824 (GRCm39) |
R484Q |
probably damaging |
Het |
| Nr4a1 |
T |
C |
15: 101,169,645 (GRCm39) |
I305T |
probably benign |
Het |
| Or1j11 |
C |
T |
2: 36,311,886 (GRCm39) |
H159Y |
probably damaging |
Het |
| Or2z2 |
G |
A |
11: 58,346,257 (GRCm39) |
R173W |
probably damaging |
Het |
| Pabir2 |
T |
A |
X: 52,342,933 (GRCm39) |
Q201H |
probably benign |
Het |
| Pcdhb5 |
T |
C |
18: 37,455,393 (GRCm39) |
V591A |
possibly damaging |
Het |
| Pdia3 |
T |
C |
2: 121,262,144 (GRCm39) |
I205T |
probably benign |
Het |
| Pdia4 |
A |
T |
6: 47,790,161 (GRCm39) |
D26E |
unknown |
Het |
| Phactr3 |
C |
A |
2: 177,924,940 (GRCm39) |
L292M |
probably damaging |
Het |
| Phf21b |
T |
A |
15: 84,738,963 (GRCm39) |
I21F |
probably benign |
Het |
| Pign |
A |
G |
1: 105,482,223 (GRCm39) |
V791A |
probably damaging |
Het |
| Pitpna |
A |
G |
11: 75,499,929 (GRCm39) |
|
probably null |
Het |
| Piwil1 |
G |
T |
5: 128,824,903 (GRCm39) |
E534* |
probably null |
Het |
| Plcz1 |
T |
A |
6: 139,938,775 (GRCm39) |
I526F |
probably benign |
Het |
| Pms2 |
A |
T |
5: 143,862,714 (GRCm39) |
K607I |
probably benign |
Het |
| Pnn |
T |
A |
12: 59,118,399 (GRCm39) |
N327K |
probably damaging |
Het |
| Pogz |
C |
T |
3: 94,786,160 (GRCm39) |
T863I |
probably benign |
Het |
| Polq |
C |
T |
16: 36,882,471 (GRCm39) |
T1545I |
probably benign |
Het |
| Psd4 |
G |
A |
2: 24,287,468 (GRCm39) |
E467K |
probably benign |
Het |
| Pstpip2 |
T |
A |
18: 77,959,499 (GRCm39) |
L198Q |
probably damaging |
Het |
| Pzp |
T |
C |
6: 128,479,188 (GRCm39) |
Y655C |
probably damaging |
Het |
| Qrsl1 |
C |
T |
10: 43,770,541 (GRCm39) |
G117E |
probably damaging |
Het |
| Rad54b |
G |
A |
4: 11,601,669 (GRCm39) |
C408Y |
probably damaging |
Het |
| Ralb |
T |
A |
1: 119,403,797 (GRCm39) |
Q110L |
possibly damaging |
Het |
| Rrm2 |
A |
G |
12: 24,763,151 (GRCm39) |
K218E |
probably damaging |
Het |
| Siglece |
A |
G |
7: 43,309,360 (GRCm39) |
F66S |
probably benign |
Het |
| Slc17a8 |
A |
T |
10: 89,442,627 (GRCm39) |
C69S |
unknown |
Het |
| Slc1a6 |
T |
A |
10: 78,648,758 (GRCm39) |
V493E |
probably damaging |
Het |
| Slc38a11 |
A |
T |
2: 65,193,860 (GRCm39) |
|
probably null |
Het |
| Smarcal1 |
G |
A |
1: 72,625,258 (GRCm39) |
G135D |
possibly damaging |
Het |
| Snrnp70 |
T |
A |
7: 45,026,644 (GRCm39) |
R242* |
probably null |
Het |
| St3gal5 |
T |
C |
6: 72,109,077 (GRCm39) |
L55P |
probably damaging |
Het |
| Sulf1 |
A |
G |
1: 12,908,661 (GRCm39) |
N558S |
probably benign |
Het |
| Supt6 |
T |
C |
11: 78,123,366 (GRCm39) |
I104V |
possibly damaging |
Het |
| Tas2r113 |
T |
A |
6: 132,870,292 (GRCm39) |
Y107N |
probably damaging |
Het |
| Tcf7 |
A |
G |
11: 52,147,891 (GRCm39) |
V187A |
probably benign |
Het |
| Tdrd9 |
G |
A |
12: 112,011,246 (GRCm39) |
G1152R |
probably damaging |
Het |
| Tfpi |
A |
G |
2: 84,288,451 (GRCm39) |
Y9H |
probably benign |
Het |
| Tnk2 |
G |
A |
16: 32,498,960 (GRCm39) |
V758I |
probably damaging |
Het |
| Trim72 |
A |
G |
7: 127,608,254 (GRCm39) |
I251V |
probably benign |
Het |
| Trip12 |
T |
A |
1: 84,705,866 (GRCm39) |
N655Y |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,581,773 (GRCm39) |
V23040A |
probably damaging |
Het |
| Tulp2 |
T |
A |
7: 45,167,367 (GRCm39) |
N188K |
probably damaging |
Het |
| Ube2c |
C |
T |
2: 164,613,282 (GRCm39) |
H67Y |
probably damaging |
Het |
| Unc80 |
C |
A |
1: 66,670,573 (GRCm39) |
P1899T |
possibly damaging |
Het |
| Usp34 |
C |
T |
11: 23,376,153 (GRCm39) |
A1879V |
probably benign |
Het |
| Vmn2r118 |
G |
A |
17: 55,918,556 (GRCm39) |
S112L |
possibly damaging |
Het |
| Wdfy3 |
A |
T |
5: 102,036,052 (GRCm39) |
V2122E |
probably benign |
Het |
| Zcchc4 |
A |
G |
5: 52,973,168 (GRCm39) |
Y344C |
probably damaging |
Het |
| Zdbf2 |
GAAAAA |
GAAAAAA |
1: 63,344,701 (GRCm39) |
|
probably null |
Het |
| Zdhhc25 |
A |
T |
15: 88,484,689 (GRCm39) |
H8L |
probably benign |
Het |
| Zfp455 |
A |
T |
13: 67,355,881 (GRCm39) |
H383L |
probably damaging |
Het |
| Zfp663 |
A |
G |
2: 165,195,211 (GRCm39) |
I336T |
probably benign |
Het |
| Zfp738 |
T |
A |
13: 67,818,476 (GRCm39) |
H505L |
probably damaging |
Het |
| Zfp84 |
T |
G |
7: 29,474,796 (GRCm39) |
F23V |
possibly damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4960:Anapc1
|
UTSW |
2 |
128,526,514 (GRCm39) |
missense |
probably benign |
0.23 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGACATCCACCTTAGAGCCG -3'
(R):5'- AACCCTGAACACTTGCACTGAG -3'
Sequencing Primer
(F):5'- CTTAGAGCCGCCATGTTGGAAATG -3'
(R):5'- CACTGAGCACTTTGAGATCAGTTGAG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation