Incidental Mutation 'R1856:Igsf10'
| ID |
206092 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Igsf10
|
| Ensembl Gene |
ENSMUSG00000036334 |
| Gene Name |
immunoglobulin superfamily, member 10 |
| Synonyms |
Adlican2, CMF608, 6530405F15Rik |
| MMRRC Submission |
039880-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.279)
|
| Stock # |
R1856 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
59316735-59344394 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 59331272 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 496
(D496G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141391
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039419]
[ENSMUST00000193455]
[ENSMUST00000194546]
|
| AlphaFold |
Q3V1M1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039419
AA Change: D496G
PolyPhen 2
Score 0.633 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: D496G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000193455
AA Change: D496G
PolyPhen 2
Score 0.633 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: D496G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000194546
AA Change: D496G
PolyPhen 2
Score 0.633 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: D496G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.9%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 113 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
T |
G |
7: 120,278,181 (GRCm38) |
F1017L |
probably damaging |
Het |
| Abcb11 |
A |
C |
2: 69,245,923 (GRCm38) |
V1147G |
probably damaging |
Het |
| Abcc10 |
T |
A |
17: 46,306,603 (GRCm38) |
S1128C |
probably damaging |
Het |
| Adam6a |
G |
A |
12: 113,545,303 (GRCm38) |
C432Y |
probably damaging |
Het |
| Adamdec1 |
C |
T |
14: 68,570,948 (GRCm38) |
V318M |
probably damaging |
Het |
| Ahnak |
C |
A |
19: 9,002,048 (GRCm38) |
S232Y |
possibly damaging |
Het |
| Amt |
A |
C |
9: 108,297,162 (GRCm38) |
H42P |
probably damaging |
Het |
| Anapc1 |
A |
T |
2: 128,659,788 (GRCm38) |
L778Q |
probably damaging |
Het |
| Ankhd1 |
G |
A |
18: 36,644,527 (GRCm38) |
A1588T |
probably benign |
Het |
| Anln |
A |
T |
9: 22,353,331 (GRCm38) |
L881Q |
probably damaging |
Het |
| Appl1 |
A |
G |
14: 26,927,749 (GRCm38) |
S607P |
probably damaging |
Het |
| Arg2 |
G |
T |
12: 79,147,662 (GRCm38) |
V87L |
probably benign |
Het |
| Atp13a2 |
C |
T |
4: 141,004,012 (GRCm38) |
P869L |
probably benign |
Het |
| Atxn7l1 |
T |
A |
12: 33,358,770 (GRCm38) |
D310E |
probably damaging |
Het |
| Cd6 |
A |
T |
19: 10,798,602 (GRCm38) |
D164E |
probably damaging |
Het |
| Cdan1 |
C |
A |
2: 120,724,936 (GRCm38) |
V775L |
probably benign |
Het |
| Cep164 |
A |
T |
9: 45,775,758 (GRCm38) |
|
probably null |
Het |
| Cep41 |
A |
G |
6: 30,661,006 (GRCm38) |
S61P |
probably damaging |
Het |
| Clcn7 |
C |
A |
17: 25,160,471 (GRCm38) |
D764E |
probably damaging |
Het |
| Cog2 |
G |
A |
8: 124,551,403 (GRCm38) |
G703S |
possibly damaging |
Het |
| Cramp1l |
T |
C |
17: 24,968,978 (GRCm38) |
D1214G |
probably damaging |
Het |
| Cst7 |
G |
T |
2: 150,577,708 (GRCm38) |
C98F |
probably damaging |
Het |
| Ctc1 |
T |
A |
11: 69,034,658 (GRCm38) |
L1007Q |
probably damaging |
Het |
| Cyb5r4 |
G |
A |
9: 87,022,209 (GRCm38) |
A11T |
possibly damaging |
Het |
| Dcaf8 |
A |
G |
1: 172,175,553 (GRCm38) |
D306G |
probably damaging |
Het |
| Defb38 |
T |
A |
8: 19,023,576 (GRCm38) |
K27I |
probably benign |
Het |
| Disp3 |
T |
C |
4: 148,271,632 (GRCm38) |
E257G |
probably damaging |
Het |
| Dnajc6 |
T |
C |
4: 101,598,988 (GRCm38) |
S58P |
probably damaging |
Het |
| Dock10 |
A |
T |
1: 80,606,568 (GRCm38) |
D140E |
possibly damaging |
Het |
| Dopey1 |
T |
C |
9: 86,492,004 (GRCm38) |
V172A |
probably damaging |
Het |
| Dync1h1 |
G |
A |
12: 110,636,509 (GRCm38) |
E2195K |
probably benign |
Het |
| Eci3 |
C |
T |
13: 34,953,028 (GRCm38) |
A171T |
possibly damaging |
Het |
| Eml2 |
A |
G |
7: 19,194,061 (GRCm38) |
D284G |
probably damaging |
Het |
| Eml5 |
T |
C |
12: 98,810,584 (GRCm38) |
D1377G |
probably damaging |
Het |
| Fam186a |
T |
C |
15: 99,940,302 (GRCm38) |
E2687G |
possibly damaging |
Het |
| Fut9 |
A |
C |
4: 25,620,352 (GRCm38) |
L154R |
probably damaging |
Het |
| Gabrb2 |
A |
G |
11: 42,626,713 (GRCm38) |
N454S |
probably benign |
Het |
| Gm438 |
T |
A |
4: 144,777,883 (GRCm38) |
M233L |
probably benign |
Het |
| Gpr183 |
T |
A |
14: 121,954,741 (GRCm38) |
I123L |
probably benign |
Het |
| Gucy1b1 |
A |
T |
3: 82,058,352 (GRCm38) |
N62K |
probably benign |
Het |
| Hcrtr2 |
T |
C |
9: 76,259,785 (GRCm38) |
N90S |
probably damaging |
Het |
| Hectd1 |
A |
T |
12: 51,744,794 (GRCm38) |
L2556Q |
probably damaging |
Het |
| Hfm1 |
T |
A |
5: 106,847,676 (GRCm38) |
M1290L |
probably benign |
Het |
| Hgsnat |
A |
G |
8: 25,957,256 (GRCm38) |
W337R |
probably benign |
Het |
| Hmbox1 |
T |
C |
14: 64,828,648 (GRCm38) |
Y291C |
probably damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,721,664 (GRCm38) |
N1749S |
probably benign |
Het |
| Iqch |
C |
T |
9: 63,534,337 (GRCm38) |
|
probably null |
Het |
| Irf6 |
A |
G |
1: 193,167,535 (GRCm38) |
D255G |
probably benign |
Het |
| Kif9 |
G |
A |
9: 110,517,719 (GRCm38) |
G642R |
probably null |
Het |
| Klhl20 |
A |
G |
1: 161,106,742 (GRCm38) |
Y236H |
probably benign |
Het |
| Krt39 |
T |
A |
11: 99,519,088 (GRCm38) |
K208* |
probably null |
Het |
| Lama3 |
T |
A |
18: 12,537,781 (GRCm38) |
L808* |
probably null |
Het |
| Lrp5 |
C |
T |
19: 3,597,346 (GRCm38) |
A1299T |
probably benign |
Het |
| Lysmd4 |
A |
G |
7: 67,226,231 (GRCm38) |
Q214R |
probably benign |
Het |
| Macf1 |
T |
A |
4: 123,369,848 (GRCm38) |
E6960V |
probably damaging |
Het |
| Mcpt2 |
A |
G |
14: 56,043,699 (GRCm38) |
E120G |
probably benign |
Het |
| Mpeg1 |
A |
G |
19: 12,462,356 (GRCm38) |
T393A |
probably benign |
Het |
| Myh4 |
G |
A |
11: 67,255,682 (GRCm38) |
E1494K |
probably damaging |
Het |
| Nbas |
T |
G |
12: 13,474,229 (GRCm38) |
S1695R |
possibly damaging |
Het |
| Nlgn1 |
G |
T |
3: 25,440,037 (GRCm38) |
Y249* |
probably null |
Het |
| Ntn4 |
C |
T |
10: 93,707,353 (GRCm38) |
R314W |
probably damaging |
Het |
| Nup107 |
A |
G |
10: 117,750,906 (GRCm38) |
L910P |
probably damaging |
Het |
| Obscn |
T |
A |
11: 59,040,296 (GRCm38) |
D5838V |
probably damaging |
Het |
| Olfr1218 |
G |
A |
2: 89,054,859 (GRCm38) |
T189M |
possibly damaging |
Het |
| Olfr347 |
T |
C |
2: 36,734,345 (GRCm38) |
I8T |
probably benign |
Het |
| Olfr926 |
T |
C |
9: 38,877,596 (GRCm38) |
I140T |
possibly damaging |
Het |
| Olfr978 |
T |
C |
9: 39,994,359 (GRCm38) |
I183T |
probably benign |
Het |
| Otogl |
G |
T |
10: 107,854,264 (GRCm38) |
S915Y |
possibly damaging |
Het |
| P2rx7 |
T |
A |
5: 122,681,032 (GRCm38) |
C506S |
probably damaging |
Het |
| P4hb |
T |
C |
11: 120,563,218 (GRCm38) |
E350G |
probably benign |
Het |
| Papolg |
A |
T |
11: 23,867,379 (GRCm38) |
V606E |
probably benign |
Het |
| Pappa |
A |
T |
4: 65,340,743 (GRCm38) |
D1576V |
probably damaging |
Het |
| Pclo |
G |
T |
5: 14,778,552 (GRCm38) |
V1402F |
probably damaging |
Het |
| Pdcd11 |
A |
G |
19: 47,098,187 (GRCm38) |
T211A |
probably benign |
Het |
| Pdzd2 |
T |
C |
15: 12,373,855 (GRCm38) |
R2065G |
possibly damaging |
Het |
| Plcl2 |
T |
C |
17: 50,607,850 (GRCm38) |
V629A |
probably benign |
Het |
| Prkcsh |
G |
A |
9: 22,004,575 (GRCm38) |
V92I |
possibly damaging |
Het |
| Prpf19 |
G |
T |
19: 10,902,416 (GRCm38) |
V320F |
probably damaging |
Het |
| Ptpn3 |
T |
A |
4: 57,239,682 (GRCm38) |
I283F |
probably damaging |
Het |
| Rcc2 |
T |
A |
4: 140,720,604 (GRCm38) |
D480E |
probably benign |
Het |
| Rnf182 |
G |
A |
13: 43,668,042 (GRCm38) |
C23Y |
probably damaging |
Het |
| Rnf186 |
C |
T |
4: 138,967,362 (GRCm38) |
T71I |
probably benign |
Het |
| Scyl3 |
A |
G |
1: 163,933,696 (GRCm38) |
|
probably null |
Het |
| Slc12a6 |
G |
T |
2: 112,335,927 (GRCm38) |
|
probably null |
Het |
| Slc1a2 |
C |
A |
2: 102,777,567 (GRCm38) |
S520Y |
probably damaging |
Het |
| Slc35e2 |
T |
A |
4: 155,611,729 (GRCm38) |
L191Q |
probably damaging |
Het |
| Snrnp40 |
C |
G |
4: 130,378,043 (GRCm38) |
|
probably null |
Het |
| Snx33 |
T |
C |
9: 56,926,011 (GRCm38) |
H258R |
possibly damaging |
Het |
| Tecpr2 |
A |
T |
12: 110,933,064 (GRCm38) |
H622L |
probably benign |
Het |
| Thbs3 |
A |
T |
3: 89,226,406 (GRCm38) |
E888D |
probably damaging |
Het |
| Tlk2 |
T |
C |
11: 105,221,298 (GRCm38) |
L159P |
probably benign |
Het |
| Tmem70 |
A |
T |
1: 16,677,273 (GRCm38) |
T205S |
probably damaging |
Het |
| Trappc10 |
T |
A |
10: 78,196,451 (GRCm38) |
H1001L |
probably benign |
Het |
| Trim12a |
T |
C |
7: 104,300,857 (GRCm38) |
T292A |
probably benign |
Het |
| Trip11 |
G |
A |
12: 101,883,333 (GRCm38) |
R92* |
probably null |
Het |
| Trpa1 |
G |
A |
1: 14,899,388 (GRCm38) |
Q386* |
probably null |
Het |
| Trpc4 |
T |
A |
3: 54,279,989 (GRCm38) |
V454D |
probably damaging |
Het |
| Ttc36 |
A |
T |
9: 44,802,754 (GRCm38) |
D22E |
probably benign |
Het |
| Ttk |
A |
T |
9: 83,869,263 (GRCm38) |
I798F |
probably damaging |
Het |
| Ttn |
T |
C |
2: 76,743,633 (GRCm38) |
I17312V |
probably damaging |
Het |
| Txndc15 |
A |
T |
13: 55,718,062 (GRCm38) |
E113V |
possibly damaging |
Het |
| Ube2d4 |
T |
A |
15: 58,846,599 (GRCm38) |
|
noncoding transcript |
Het |
| Urb1 |
T |
A |
16: 90,761,695 (GRCm38) |
T1723S |
probably benign |
Het |
| Vmn1r65 |
A |
T |
7: 6,008,266 (GRCm38) |
V323D |
possibly damaging |
Het |
| Vmn2r54 |
A |
G |
7: 12,632,311 (GRCm38) |
M232T |
probably benign |
Het |
| Wdr59 |
A |
G |
8: 111,476,181 (GRCm38) |
S577P |
probably damaging |
Het |
| Wfikkn2 |
C |
T |
11: 94,238,123 (GRCm38) |
W397* |
probably null |
Het |
| Ypel1 |
T |
A |
16: 17,081,647 (GRCm38) |
|
probably null |
Het |
| Ythdf1 |
T |
A |
2: 180,910,970 (GRCm38) |
D484V |
probably damaging |
Het |
| Zdhhc17 |
A |
G |
10: 110,947,293 (GRCm38) |
|
probably null |
Het |
| Zfp472 |
A |
T |
17: 32,965,913 (GRCm38) |
H2L |
possibly damaging |
Het |
| Zfp953 |
A |
T |
13: 67,345,358 (GRCm38) |
M74K |
probably benign |
Het |
| Zmat4 |
C |
T |
8: 23,929,135 (GRCm38) |
T61M |
probably benign |
Het |
|
| Other mutations in Igsf10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00773:Igsf10
|
APN |
3 |
59,331,539 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL00790:Igsf10
|
APN |
3 |
59,319,517 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00916:Igsf10
|
APN |
3 |
59,331,127 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL00928:Igsf10
|
APN |
3 |
59,330,597 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01066:Igsf10
|
APN |
3 |
59,327,782 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01107:Igsf10
|
APN |
3 |
59,331,524 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01420:Igsf10
|
APN |
3 |
59,319,650 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL01533:Igsf10
|
APN |
3 |
59,319,230 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01537:Igsf10
|
APN |
3 |
59,330,031 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01676:Igsf10
|
APN |
3 |
59,329,335 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01676:Igsf10
|
APN |
3 |
59,326,011 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL01960:Igsf10
|
APN |
3 |
59,318,737 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02123:Igsf10
|
APN |
3 |
59,318,660 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02198:Igsf10
|
APN |
3 |
59,325,978 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02268:Igsf10
|
APN |
3 |
59,331,152 (GRCm38) |
nonsense |
probably null |
|
|
IGL02313:Igsf10
|
APN |
3 |
59,330,690 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02368:Igsf10
|
APN |
3 |
59,328,231 (GRCm38) |
missense |
probably benign |
|
|
IGL02494:Igsf10
|
APN |
3 |
59,328,006 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02549:Igsf10
|
APN |
3 |
59,329,241 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02616:Igsf10
|
APN |
3 |
59,318,606 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL02957:Igsf10
|
APN |
3 |
59,330,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03067:Igsf10
|
APN |
3 |
59,318,918 (GRCm38) |
missense |
probably benign |
0.25 |
|
IGL03104:Igsf10
|
APN |
3 |
59,319,484 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03124:Igsf10
|
APN |
3 |
59,319,665 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03212:Igsf10
|
APN |
3 |
59,328,165 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL03347:Igsf10
|
APN |
3 |
59,331,900 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL03357:Igsf10
|
APN |
3 |
59,336,211 (GRCm38) |
missense |
probably benign |
0.35 |
|
F6893:Igsf10
|
UTSW |
3 |
59,331,060 (GRCm38) |
missense |
probably damaging |
1.00 |
|
FR4449:Igsf10
|
UTSW |
3 |
59,319,110 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Igsf10
|
UTSW |
3 |
59,328,158 (GRCm38) |
missense |
probably benign |
0.06 |
|
PIT4402001:Igsf10
|
UTSW |
3 |
59,325,579 (GRCm38) |
missense |
probably benign |
0.00 |
|
PIT4810001:Igsf10
|
UTSW |
3 |
59,318,482 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0068:Igsf10
|
UTSW |
3 |
59,330,624 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0095:Igsf10
|
UTSW |
3 |
59,331,196 (GRCm38) |
nonsense |
probably null |
|
|
R0095:Igsf10
|
UTSW |
3 |
59,331,196 (GRCm38) |
nonsense |
probably null |
|
|
R0112:Igsf10
|
UTSW |
3 |
59,326,008 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0141:Igsf10
|
UTSW |
3 |
59,330,832 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0538:Igsf10
|
UTSW |
3 |
59,320,106 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0551:Igsf10
|
UTSW |
3 |
59,328,668 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0556:Igsf10
|
UTSW |
3 |
59,328,875 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0582:Igsf10
|
UTSW |
3 |
59,319,767 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0630:Igsf10
|
UTSW |
3 |
59,326,062 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0675:Igsf10
|
UTSW |
3 |
59,328,594 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0948:Igsf10
|
UTSW |
3 |
59,331,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1252:Igsf10
|
UTSW |
3 |
59,331,848 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1412:Igsf10
|
UTSW |
3 |
59,327,775 (GRCm38) |
splice site |
probably benign |
|
|
R1473:Igsf10
|
UTSW |
3 |
59,318,767 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1585:Igsf10
|
UTSW |
3 |
59,330,417 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1650:Igsf10
|
UTSW |
3 |
59,326,162 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1660:Igsf10
|
UTSW |
3 |
59,331,285 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1671:Igsf10
|
UTSW |
3 |
59,328,500 (GRCm38) |
nonsense |
probably null |
|
|
R1748:Igsf10
|
UTSW |
3 |
59,319,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Igsf10
|
UTSW |
3 |
59,329,196 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1912:Igsf10
|
UTSW |
3 |
59,329,572 (GRCm38) |
missense |
probably benign |
0.40 |
|
R2148:Igsf10
|
UTSW |
3 |
59,336,577 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R2155:Igsf10
|
UTSW |
3 |
59,331,680 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Igsf10
|
UTSW |
3 |
59,331,866 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2511:Igsf10
|
UTSW |
3 |
59,331,866 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2680:Igsf10
|
UTSW |
3 |
59,325,454 (GRCm38) |
missense |
probably benign |
0.14 |
|
R2913:Igsf10
|
UTSW |
3 |
59,331,736 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R2927:Igsf10
|
UTSW |
3 |
59,329,427 (GRCm38) |
missense |
probably benign |
|
|
R3547:Igsf10
|
UTSW |
3 |
59,336,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3547:Igsf10
|
UTSW |
3 |
59,330,541 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3548:Igsf10
|
UTSW |
3 |
59,336,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3620:Igsf10
|
UTSW |
3 |
59,336,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3732:Igsf10
|
UTSW |
3 |
59,325,714 (GRCm38) |
missense |
probably benign |
0.29 |
|
R3743:Igsf10
|
UTSW |
3 |
59,326,125 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R3973:Igsf10
|
UTSW |
3 |
59,331,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4005:Igsf10
|
UTSW |
3 |
59,328,560 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4184:Igsf10
|
UTSW |
3 |
59,319,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4302:Igsf10
|
UTSW |
3 |
59,318,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4404:Igsf10
|
UTSW |
3 |
59,329,551 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4575:Igsf10
|
UTSW |
3 |
59,330,100 (GRCm38) |
missense |
probably benign |
|
|
R4676:Igsf10
|
UTSW |
3 |
59,325,949 (GRCm38) |
missense |
probably benign |
0.23 |
|
R4700:Igsf10
|
UTSW |
3 |
59,320,330 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4765:Igsf10
|
UTSW |
3 |
59,329,705 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4986:Igsf10
|
UTSW |
3 |
59,328,606 (GRCm38) |
missense |
probably benign |
0.24 |
|
R5012:Igsf10
|
UTSW |
3 |
59,318,722 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5070:Igsf10
|
UTSW |
3 |
59,328,293 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5083:Igsf10
|
UTSW |
3 |
59,326,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5336:Igsf10
|
UTSW |
3 |
59,320,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5462:Igsf10
|
UTSW |
3 |
59,325,754 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5648:Igsf10
|
UTSW |
3 |
59,328,153 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5810:Igsf10
|
UTSW |
3 |
59,319,071 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5871:Igsf10
|
UTSW |
3 |
59,330,411 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R5880:Igsf10
|
UTSW |
3 |
59,330,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5935:Igsf10
|
UTSW |
3 |
59,328,157 (GRCm38) |
missense |
probably benign |
0.12 |
|
R5979:Igsf10
|
UTSW |
3 |
59,336,473 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6145:Igsf10
|
UTSW |
3 |
59,331,656 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R6222:Igsf10
|
UTSW |
3 |
59,318,915 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6224:Igsf10
|
UTSW |
3 |
59,325,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6264:Igsf10
|
UTSW |
3 |
59,328,507 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6283:Igsf10
|
UTSW |
3 |
59,319,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6336:Igsf10
|
UTSW |
3 |
59,330,339 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6490:Igsf10
|
UTSW |
3 |
59,329,571 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6785:Igsf10
|
UTSW |
3 |
59,319,244 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6873:Igsf10
|
UTSW |
3 |
59,328,444 (GRCm38) |
missense |
probably benign |
|
|
R6889:Igsf10
|
UTSW |
3 |
59,331,933 (GRCm38) |
missense |
probably benign |
|
|
R7024:Igsf10
|
UTSW |
3 |
59,331,701 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7056:Igsf10
|
UTSW |
3 |
59,331,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7128:Igsf10
|
UTSW |
3 |
59,328,905 (GRCm38) |
missense |
probably benign |
|
|
R7251:Igsf10
|
UTSW |
3 |
59,319,454 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7313:Igsf10
|
UTSW |
3 |
59,329,416 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7340:Igsf10
|
UTSW |
3 |
59,325,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7447:Igsf10
|
UTSW |
3 |
59,331,801 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7506:Igsf10
|
UTSW |
3 |
59,319,354 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7678:Igsf10
|
UTSW |
3 |
59,319,340 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7695:Igsf10
|
UTSW |
3 |
59,326,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7709:Igsf10
|
UTSW |
3 |
59,331,543 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7749:Igsf10
|
UTSW |
3 |
59,329,128 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R7808:Igsf10
|
UTSW |
3 |
59,328,068 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7850:Igsf10
|
UTSW |
3 |
59,319,632 (GRCm38) |
missense |
probably benign |
0.33 |
|
R7879:Igsf10
|
UTSW |
3 |
59,330,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7886:Igsf10
|
UTSW |
3 |
59,328,327 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7891:Igsf10
|
UTSW |
3 |
59,328,411 (GRCm38) |
nonsense |
probably null |
|
|
R7946:Igsf10
|
UTSW |
3 |
59,319,704 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R7948:Igsf10
|
UTSW |
3 |
59,331,858 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8004:Igsf10
|
UTSW |
3 |
59,329,709 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8096:Igsf10
|
UTSW |
3 |
59,328,959 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8141:Igsf10
|
UTSW |
3 |
59,330,528 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8183:Igsf10
|
UTSW |
3 |
59,330,615 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8203:Igsf10
|
UTSW |
3 |
59,328,833 (GRCm38) |
missense |
probably benign |
0.11 |
|
R8325:Igsf10
|
UTSW |
3 |
59,318,533 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8350:Igsf10
|
UTSW |
3 |
59,331,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8387:Igsf10
|
UTSW |
3 |
59,329,143 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8488:Igsf10
|
UTSW |
3 |
59,320,010 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8697:Igsf10
|
UTSW |
3 |
59,318,887 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8786:Igsf10
|
UTSW |
3 |
59,330,642 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8804:Igsf10
|
UTSW |
3 |
59,336,455 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8886:Igsf10
|
UTSW |
3 |
59,329,989 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8902:Igsf10
|
UTSW |
3 |
59,336,212 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8906:Igsf10
|
UTSW |
3 |
59,326,318 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8917:Igsf10
|
UTSW |
3 |
59,319,467 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R9051:Igsf10
|
UTSW |
3 |
59,329,247 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9178:Igsf10
|
UTSW |
3 |
59,326,059 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R9228:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9230:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9231:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9232:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9417:Igsf10
|
UTSW |
3 |
59,329,105 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9609:Igsf10
|
UTSW |
3 |
59,319,448 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9631:Igsf10
|
UTSW |
3 |
59,330,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9689:Igsf10
|
UTSW |
3 |
59,326,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9762:Igsf10
|
UTSW |
3 |
59,329,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9770:Igsf10
|
UTSW |
3 |
59,319,778 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9798:Igsf10
|
UTSW |
3 |
59,331,705 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Igsf10
|
UTSW |
3 |
59,329,938 (GRCm38) |
missense |
possibly damaging |
0.59 |
|
Z1177:Igsf10
|
UTSW |
3 |
59,329,605 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGGGCTCTACCACAGTTATCC -3'
(R):5'- CCTGCAGCTCAACAGAACTG -3'
Sequencing Primer
(F):5'- CAGCATCATTGGTGCTTATGC -3'
(R):5'- TGCTACCACACTTAGCACATTACAG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation