Mutagenetix > Incidental Mutation

Incidental Mutation 'R1824:Magi1'

206667

Institutional Source

Beutler Lab

Gene Symbol

Magi1

Ensembl Gene

ENSMUSG00000045095

Gene Name

membrane associated guanylate kinase, WW and PDZ domain containing 1

Synonyms

Baiap1, Gukmi1, AIP3, BAP1, WWP3

MMRRC Submission

039852-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.593) question?

Stock #

R1824 (G1)

Quality Score

130

Status

Not validated

Chromosome

Chromosomal Location

93652436-94260898 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 93676620 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 913 (V913A)

Ref Sequence

ENSEMBL: ENSMUSP00000144881 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000055224] [ENSMUST00000089317] [ENSMUST00000093769] [ENSMUST00000203519] [ENSMUST00000203688] [ENSMUST00000204347] [ENSMUST00000204532]

AlphaFold

Q6RHR9

Predicted Effect

probably benign
Transcript: ENSMUST00000055224
AA Change: V872A

PolyPhen 2 Score 0.250 (Sensitivity: 0.91; Specificity: 0.88)

SMART Domains

Protein: ENSMUSP00000062085
Gene: ENSMUSG00000045095
AA Change: V872A

Domain	Start	End	E-Value	Type
PDZ	26	105	8.04e-5	SMART
GuKc	111	295	2.55e-49	SMART
WW	301	333	9.65e-11	SMART
WW	348	380	2.88e-9	SMART
low complexity region	390	402	N/A	INTRINSIC
low complexity region	410	428	N/A	INTRINSIC
PDZ	460	536	3.71e-18	SMART
PDZ	631	703	4.68e-15	SMART
low complexity region	707	714	N/A	INTRINSIC
low complexity region	720	733	N/A	INTRINSIC
PDZ	800	876	4.64e-19	SMART
low complexity region	920	942	N/A	INTRINSIC
PDB:1UEW\|A	945	977	2e-6	PDB
PDZ	1043	1117	1.26e-20	SMART
low complexity region	1152	1164	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000089317
AA Change: V913A

PolyPhen 2 Score 0.870 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000086730
Gene: ENSMUSG00000045095
AA Change: V913A

Domain	Start	End	E-Value	Type
PDZ	26	105	4e-7	SMART
GuKc	111	295	1.3e-51	SMART
WW	301	333	5.8e-13	SMART
WW	360	392	1.7e-11	SMART
low complexity region	402	414	N/A	INTRINSIC
low complexity region	422	440	N/A	INTRINSIC
PDZ	472	548	1.9e-20	SMART
PDZ	643	715	2.3e-17	SMART
low complexity region	733	746	N/A	INTRINSIC
PDZ	841	917	2.4e-21	SMART
low complexity region	961	983	N/A	INTRINSIC
PDZ	999	1074	6.1e-25	SMART
PDZ	1140	1214	6.1e-23	SMART
low complexity region	1347	1357	N/A	INTRINSIC
low complexity region	1366	1423	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000093769
AA Change: V685A

PolyPhen 2 Score 0.883 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000091283
Gene: ENSMUSG00000045095
AA Change: V685A

Domain	Start	End	E-Value	Type
low complexity region	10	15	N/A	INTRINSIC
WW	74	106	9.65e-11	SMART
WW	133	165	2.88e-9	SMART
low complexity region	175	187	N/A	INTRINSIC
low complexity region	195	213	N/A	INTRINSIC
PDZ	245	321	3.71e-18	SMART
PDZ	416	488	4.68e-15	SMART
low complexity region	492	499	N/A	INTRINSIC
low complexity region	505	518	N/A	INTRINSIC
PDZ	613	689	4.64e-19	SMART
low complexity region	733	755	N/A	INTRINSIC
PDZ	771	858	2.3e-23	SMART
PDZ	924	998	1.26e-20	SMART
low complexity region	1131	1141	N/A	INTRINSIC
low complexity region	1150	1207	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000203519
AA Change: V884A

PolyPhen 2 Score 0.638 (Sensitivity: 0.87; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000145244
Gene: ENSMUSG00000045095
AA Change: V884A

Domain	Start	End	E-Value	Type
PDZ	26	105	8.04e-5	SMART
GuKc	111	295	2.55e-49	SMART
WW	301	333	9.65e-11	SMART
WW	360	392	2.88e-9	SMART
low complexity region	402	414	N/A	INTRINSIC
low complexity region	422	440	N/A	INTRINSIC
PDZ	472	548	3.71e-18	SMART
PDZ	643	715	4.68e-15	SMART
low complexity region	719	726	N/A	INTRINSIC
low complexity region	732	745	N/A	INTRINSIC
PDZ	812	888	4.64e-19	SMART
low complexity region	932	954	N/A	INTRINSIC
PDB:1UEW\|A	957	989	2e-6	PDB
PDZ	1055	1115	1.13e-8	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000203688
AA Change: V686A

PolyPhen 2 Score 0.487 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000145515
Gene: ENSMUSG00000045095
AA Change: V686A

Domain	Start	End	E-Value	Type
Pfam:MAGI_u1	1	34	2.9e-17	PFAM
WW	74	106	9.65e-11	SMART
WW	133	165	2.88e-9	SMART
low complexity region	175	187	N/A	INTRINSIC
low complexity region	195	213	N/A	INTRINSIC
PDZ	245	321	3.71e-18	SMART
PDZ	416	488	4.68e-15	SMART
low complexity region	506	519	N/A	INTRINSIC
PDZ	614	690	4.64e-19	SMART
low complexity region	734	756	N/A	INTRINSIC
PDZ	772	858	1.74e-23	SMART
PDZ	924	998	1.26e-20	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000204347
AA Change: V913A

PolyPhen 2 Score 0.941 (Sensitivity: 0.80; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000144881
Gene: ENSMUSG00000045095
AA Change: V913A

Domain	Start	End	E-Value	Type
PDZ	26	105	4e-7	SMART
GuKc	111	295	1.3e-51	SMART
WW	301	333	5.8e-13	SMART
WW	360	392	1.7e-11	SMART
low complexity region	402	414	N/A	INTRINSIC
low complexity region	422	440	N/A	INTRINSIC
PDZ	472	548	1.9e-20	SMART
PDZ	643	715	2.3e-17	SMART
low complexity region	733	746	N/A	INTRINSIC
PDZ	841	917	2.4e-21	SMART
low complexity region	961	983	N/A	INTRINSIC
PDZ	999	1086	1.1e-25	SMART
PDZ	1152	1226	6.1e-23	SMART
low complexity region	1261	1273	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000204532

SMART Domains

Protein: ENSMUSP00000144769
Gene: ENSMUSG00000045095

Domain	Start	End	E-Value	Type
Pfam:MAGI_u1	1	34	1.8e-14	PFAM
WW	74	106	5.8e-13	SMART
WW	133	165	1.7e-11	SMART
low complexity region	175	187	N/A	INTRINSIC
low complexity region	195	213	N/A	INTRINSIC
PDZ	245	321	1.9e-20	SMART
PDZ	416	488	7.3e-17	SMART

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.2%
20x: 92.2%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(165) : Targeted(2) Gene trapped(163)

Other mutations in this stock

Total: 103 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930533K18Rik	T	C	10: 70,708,086 (GRCm39)		noncoding transcript	Het
Aadacl2fm1	C	A	3: 59,840,001 (GRCm39)	Y24*	probably null	Het
Abl1	T	A	2: 31,690,656 (GRCm39)	M706K	probably benign	Het
Abtb1	T	C	6: 88,813,536 (GRCm39)	T401A	probably benign	Het
Acd	A	G	8: 106,427,122 (GRCm39)	L96P	probably damaging	Het
Arsi	T	A	18: 61,045,369 (GRCm39)	W20R	probably damaging	Het
Arsi	G	A	18: 61,049,723 (GRCm39)	G202E	probably benign	Het
Asic3	C	T	5: 24,618,749 (GRCm39)	Q14*	probably null	Het
Asxl3	T	A	18: 22,655,125 (GRCm39)	I1045N	probably damaging	Het
Atr	T	C	9: 95,818,474 (GRCm39)	I2149T	probably damaging	Het
Begain	A	G	12: 108,999,025 (GRCm39)		probably null	Het
Brca2	C	T	5: 150,460,387 (GRCm39)	T554I	possibly damaging	Het
Brd10	T	C	19: 29,693,814 (GRCm39)	N1960S	probably damaging	Het
C1s2	C	T	6: 124,612,641 (GRCm39)	V11I	probably benign	Het
Cacna1i	T	C	15: 80,260,990 (GRCm39)	F1333L	possibly damaging	Het
Camsap2	T	C	1: 136,201,521 (GRCm39)	T662A	possibly damaging	Het
Cep164	C	T	9: 45,690,226 (GRCm39)	V1367M	probably damaging	Het
Cfap46	C	A	7: 139,219,518 (GRCm39)	A1316S	probably benign	Het
Cic	T	C	7: 24,987,691 (GRCm39)	S553P	probably damaging	Het
Cilk1	T	A	9: 78,065,144 (GRCm39)	D351E	probably benign	Het
Clcn2	C	T	16: 20,534,712 (GRCm39)	A12T	probably benign	Het
Clip2	A	G	5: 134,532,081 (GRCm39)	Y540H	probably benign	Het
Coil	A	G	11: 88,872,923 (GRCm39)	N428S	possibly damaging	Het
Cpxm1	A	C	2: 130,237,617 (GRCm39)	V196G	probably damaging	Het
Cr2	A	G	1: 194,839,624 (GRCm39)	V601A	probably damaging	Het
Cyp3a25	T	A	5: 145,921,763 (GRCm39)	K390N	probably damaging	Het
Dclre1a	T	C	19: 56,535,150 (GRCm39)		probably null	Het
Dennd4a	G	C	9: 64,766,640 (GRCm39)		probably null	Het
Dlg5	T	C	14: 24,199,512 (GRCm39)	H1464R	probably benign	Het
Dmac2	T	G	7: 25,324,217 (GRCm39)	M225R	probably damaging	Het
Dnah8	T	C	17: 30,950,154 (GRCm39)	V1991A	possibly damaging	Het
Dscam	A	C	16: 96,626,781 (GRCm39)	V376G	probably benign	Het
Dync1li1	A	G	9: 114,538,252 (GRCm39)	D203G	probably benign	Het
Eva1c	A	G	16: 90,663,331 (GRCm39)	T22A	probably benign	Het
Fam110b	A	G	4: 5,799,029 (GRCm39)	D149G	probably benign	Het
Fras1	A	T	5: 96,918,547 (GRCm39)	I3528F	probably damaging	Het
Fsip1	T	C	2: 118,063,389 (GRCm39)	D360G	probably damaging	Het
Galnt14	T	C	17: 74,016,934 (GRCm39)	T41A	probably benign	Het
Gdf3	T	A	6: 122,586,921 (GRCm39)	Q2L	probably benign	Het
Glrp1	A	G	1: 88,437,511 (GRCm39)		probably null	Het
Gm3336	C	G	8: 71,173,066 (GRCm39)		probably null	Het
Gm8674	C	T	13: 50,054,844 (GRCm39)		noncoding transcript	Het
Gnat1	A	G	9: 107,553,774 (GRCm39)	Y226H	probably damaging	Het
Grk5	T	C	19: 61,078,410 (GRCm39)	V489A	probably damaging	Het
H1f8	A	G	6: 115,925,719 (GRCm39)	Y1C	probably null	Het
Igfbpl1	C	A	4: 45,826,406 (GRCm39)	A130S	probably benign	Het
Impdh1	T	A	6: 29,205,087 (GRCm39)	D261V	probably benign	Het
Itgal	T	A	7: 126,913,232 (GRCm39)	S610T	probably damaging	Het
Jcad	A	G	18: 4,649,293 (GRCm39)	T55A	probably benign	Het
Jup	G	A	11: 100,264,963 (GRCm39)	R663*	probably null	Het
Kalrn	C	T	16: 34,114,585 (GRCm39)	G556D	probably damaging	Het
Krt81	T	C	15: 101,358,020 (GRCm39)	E411G	probably damaging	Het
Lcat	T	C	8: 106,666,520 (GRCm39)	E334G	probably damaging	Het
Lhcgr	T	C	17: 89,057,585 (GRCm39)	E302G	probably benign	Het
Mrpl19	A	T	6: 81,941,060 (GRCm39)		probably null	Het
Muc4	G	T	16: 32,576,307 (GRCm39)		probably benign	Het
Mycbp2	A	G	14: 103,489,945 (GRCm39)	V953A	possibly damaging	Het
Myo3a	G	A	2: 22,401,054 (GRCm39)	V600I	probably benign	Het
Ndufv3	G	A	17: 31,750,219 (GRCm39)	R467Q	probably damaging	Het
Ngef	A	G	1: 87,430,986 (GRCm39)		probably null	Het
Nisch	A	T	14: 30,898,389 (GRCm39)		probably benign	Het
Nlrp4c	G	A	7: 6,069,955 (GRCm39)		probably null	Het
Nup153	A	T	13: 46,867,223 (GRCm39)	S154T	probably damaging	Het
Obscn	A	G	11: 58,885,658 (GRCm39)		probably benign	Het
Or2t1	T	A	14: 14,328,774 (GRCm38)	L221Q	probably damaging	Het
Or4a74	G	T	2: 89,439,693 (GRCm39)	P251H	probably damaging	Het
Or6c219	T	C	10: 129,781,206 (GRCm39)	M242V	possibly damaging	Het
Otogl	T	C	10: 107,615,692 (GRCm39)	N1869S	probably benign	Het
Phf24	G	T	4: 42,934,661 (GRCm39)	C136F	probably damaging	Het
Phldb2	A	T	16: 45,646,374 (GRCm39)	V65E	probably benign	Het
Pkhd1	C	A	1: 20,417,681 (GRCm39)	G2490V	probably damaging	Het
Prl8a8	A	T	13: 27,692,433 (GRCm39)	M186K	probably damaging	Het
Qars1	T	C	9: 108,391,809 (GRCm39)	V70A	probably damaging	Het
Rac1	C	T	5: 143,502,980 (GRCm39)	V14I	probably benign	Het
Rapgef5	T	A	12: 117,652,419 (GRCm39)		probably null	Het
Slc16a12	G	A	19: 34,648,278 (GRCm39)	T405M	possibly damaging	Het
Slc17a6	A	G	7: 51,311,294 (GRCm39)	Y336C	probably damaging	Het
Slc30a9	T	C	5: 67,505,395 (GRCm39)	L441P	probably damaging	Het
Slc45a2	T	C	15: 11,022,172 (GRCm39)	S305P	probably damaging	Het
Sod3	G	T	5: 52,525,504 (GRCm39)	V68L	probably benign	Het
Sp1	T	G	15: 102,339,438 (GRCm39)	S773A	possibly damaging	Het
Spen	C	A	4: 141,200,096 (GRCm39)	G2821C	probably damaging	Het
Tagap1	A	G	17: 7,223,425 (GRCm39)	S424P	probably benign	Het
Tbc1d22a	T	C	15: 86,119,770 (GRCm39)	V22A	possibly damaging	Het
Tfec	C	T	6: 16,840,467 (GRCm39)		probably null	Het
Thsd7a	A	T	6: 12,409,041 (GRCm39)		probably null	Het
Tnfsf15	C	A	4: 63,651,588 (GRCm39)	G112V	probably benign	Het
Tnfsf9	A	G	17: 57,412,738 (GRCm39)	T103A	probably benign	Het
Tnxb	C	T	17: 34,911,307 (GRCm39)	R1537*	probably null	Het
Tpra1	A	G	6: 88,888,805 (GRCm39)	N329S	probably benign	Het
Ttc12	A	G	9: 49,368,184 (GRCm39)	F281S	probably damaging	Het
Unc79	A	G	12: 103,025,579 (GRCm39)	N322S	probably damaging	Het
Unk	G	T	11: 115,921,268 (GRCm39)		probably benign	Het
Usp4	G	T	9: 108,225,207 (GRCm39)	G31W	probably damaging	Het
Vcan	G	T	13: 89,853,331 (GRCm39)	A543D	possibly damaging	Het
Vil1	A	C	1: 74,457,606 (GRCm39)	I80L	probably benign	Het
Vmn2r27	C	T	6: 124,208,593 (GRCm39)	G51S	probably benign	Het
Vpreb1a	A	G	16: 16,686,935 (GRCm39)		probably null	Het
Zbtb6	C	T	2: 37,319,829 (GRCm39)	C33Y	probably damaging	Het
Zfp330	A	T	8: 83,492,644 (GRCm39)	C189*	probably null	Het
Zfp942	T	A	17: 22,147,522 (GRCm39)	H369L	probably damaging	Het
Zfp943	T	A	17: 22,211,361 (GRCm39)	I149K	probably benign	Het
Zfyve19	G	A	2: 119,042,016 (GRCm39)	V162M	probably benign	Het

Other mutations in Magi1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01376:Magi1	APN	6	94,260,074 (GRCm39)	missense	possibly damaging	0.86
IGL01457:Magi1	APN	6	93,724,205 (GRCm39)	missense	probably damaging	0.99
IGL01642:Magi1	APN	6	93,663,605 (GRCm39)	missense	possibly damaging	0.69
IGL01724:Magi1	APN	6	93,769,381 (GRCm39)	splice site	probably null
IGL01967:Magi1	APN	6	93,685,115 (GRCm39)	missense	probably damaging	1.00
IGL01984:Magi1	APN	6	93,685,155 (GRCm39)	missense	probably damaging	1.00
IGL02074:Magi1	APN	6	93,722,579 (GRCm39)	missense	probably damaging	1.00
IGL02098:Magi1	APN	6	93,655,768 (GRCm39)	missense	probably damaging	1.00
IGL02225:Magi1	APN	6	93,671,007 (GRCm39)	missense	probably damaging	1.00
IGL02522:Magi1	APN	6	93,655,617 (GRCm39)	missense	possibly damaging	0.89
IGL02659:Magi1	APN	6	93,762,591 (GRCm39)	missense	possibly damaging	0.68
IGL02900:Magi1	APN	6	93,663,854 (GRCm39)	missense	probably damaging	1.00
P0007:Magi1	UTSW	6	93,722,969 (GRCm39)	missense	probably damaging	1.00
R0149:Magi1	UTSW	6	93,724,226 (GRCm39)	missense	probably damaging	1.00
R0512:Magi1	UTSW	6	93,671,045 (GRCm39)	missense	probably damaging	1.00
R1487:Magi1	UTSW	6	93,685,060 (GRCm39)	missense	probably benign	0.00
R1497:Magi1	UTSW	6	93,724,310 (GRCm39)	missense	probably damaging	1.00
R1502:Magi1	UTSW	6	93,671,151 (GRCm39)	missense	probably damaging	1.00
R2042:Magi1	UTSW	6	93,732,026 (GRCm39)	missense	probably benign
R2132:Magi1	UTSW	6	93,674,255 (GRCm39)	missense	probably damaging	0.99
R2331:Magi1	UTSW	6	93,662,543 (GRCm39)	missense	probably damaging	1.00
R2418:Magi1	UTSW	6	93,722,891 (GRCm39)	missense	probably damaging	1.00
R3076:Magi1	UTSW	6	93,734,668 (GRCm39)	missense	possibly damaging	0.63
R3551:Magi1	UTSW	6	93,676,610 (GRCm39)	missense	probably damaging	0.98
R4005:Magi1	UTSW	6	93,678,299 (GRCm39)	missense	probably damaging	1.00
R4455:Magi1	UTSW	6	93,762,438 (GRCm39)	missense	probably damaging	1.00
R4670:Magi1	UTSW	6	93,663,624 (GRCm39)	splice site	probably null
R4671:Magi1	UTSW	6	93,657,768 (GRCm39)	critical splice donor site	probably null
R4839:Magi1	UTSW	6	93,671,177 (GRCm39)	missense	probably damaging	1.00
R5132:Magi1	UTSW	6	93,660,072 (GRCm39)	critical splice acceptor site	probably null
R5147:Magi1	UTSW	6	93,724,248 (GRCm39)	missense	probably damaging	1.00
R5525:Magi1	UTSW	6	93,769,354 (GRCm39)	missense	possibly damaging	0.95
R5724:Magi1	UTSW	6	93,722,682 (GRCm39)	missense	probably damaging	1.00
R5724:Magi1	UTSW	6	93,657,852 (GRCm39)	missense	probably benign	0.03
R5846:Magi1	UTSW	6	93,662,584 (GRCm39)	missense	probably damaging	1.00
R5896:Magi1	UTSW	6	93,685,180 (GRCm39)	missense	probably damaging	1.00
R5912:Magi1	UTSW	6	93,685,126 (GRCm39)	missense	possibly damaging	0.95
R6112:Magi1	UTSW	6	93,722,571 (GRCm39)	missense	probably damaging	1.00
R6115:Magi1	UTSW	6	93,685,051 (GRCm39)	missense	possibly damaging	0.64
R6351:Magi1	UTSW	6	93,920,210 (GRCm39)	missense	possibly damaging	0.82
R6355:Magi1	UTSW	6	94,260,177 (GRCm39)	missense	probably benign	0.06
R6457:Magi1	UTSW	6	93,676,620 (GRCm39)	missense	probably damaging	1.00
R6464:Magi1	UTSW	6	93,676,770 (GRCm39)	missense	probably damaging	1.00
R6613:Magi1	UTSW	6	93,722,654 (GRCm39)	missense	probably damaging	1.00
R6661:Magi1	UTSW	6	93,920,289 (GRCm39)	missense	probably benign	0.08
R6755:Magi1	UTSW	6	93,685,158 (GRCm39)	missense	probably damaging	1.00
R6909:Magi1	UTSW	6	93,674,301 (GRCm39)	missense	probably damaging	1.00
R7180:Magi1	UTSW	6	93,792,731 (GRCm39)	missense	probably benign	0.10
R7224:Magi1	UTSW	6	93,660,070 (GRCm39)	missense	probably benign	0.34
R7447:Magi1	UTSW	6	93,722,562 (GRCm39)	missense	possibly damaging	0.63
R7517:Magi1	UTSW	6	93,685,189 (GRCm39)	missense	probably damaging	0.99
R7537:Magi1	UTSW	6	93,685,091 (GRCm39)	nonsense	probably null
R7549:Magi1	UTSW	6	93,685,095 (GRCm39)	missense	probably benign	0.19
R7566:Magi1	UTSW	6	93,655,308 (GRCm39)	missense	probably benign	0.03
R7805:Magi1	UTSW	6	93,659,927 (GRCm39)	missense	probably benign
R8022:Magi1	UTSW	6	93,674,346 (GRCm39)	missense	probably damaging	1.00
R8290:Magi1	UTSW	6	94,260,066 (GRCm39)	missense	probably damaging	1.00
R8519:Magi1	UTSW	6	93,681,330 (GRCm39)	missense	possibly damaging	0.83
R8762:Magi1	UTSW	6	93,792,789 (GRCm39)	nonsense	probably null
R8894:Magi1	UTSW	6	93,663,586 (GRCm39)	missense	probably benign	0.12
R8974:Magi1	UTSW	6	93,674,223 (GRCm39)	missense	probably damaging	1.00
R9225:Magi1	UTSW	6	93,762,511 (GRCm39)	missense	possibly damaging	0.64
R9277:Magi1	UTSW	6	93,920,234 (GRCm39)	missense	possibly damaging	0.48
R9300:Magi1	UTSW	6	93,724,209 (GRCm39)	missense	probably damaging	1.00
R9393:Magi1	UTSW	6	93,659,890 (GRCm39)	missense	probably benign	0.27
R9402:Magi1	UTSW	6	94,260,278 (GRCm39)	missense	probably benign	0.00
R9432:Magi1	UTSW	6	93,660,058 (GRCm39)	missense	probably damaging	1.00
R9567:Magi1	UTSW	6	93,659,931 (GRCm39)	critical splice donor site	probably null
R9567:Magi1	UTSW	6	93,655,431 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ACATCTGAATGACAGCAGGG -3'
(R):5'- CATGGGCCATCAGTCTTGATAG -3'

Sequencing Primer
(F):5'- GCTGGCGAGAAACAAACCATCTG -3'
(R):5'- GGGCCATCAGTCTTGATAGTAAACC -3'

Posted On

2014-06-23