Incidental Mutation 'R1824:Dennd4a'
| ID |
206685 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
039852-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R1824 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
critical splice donor site (1 bp from exon) |
| DNA Base Change (assembly) |
G to C
at 64859358 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000038890
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215025
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930533K18Rik |
T |
C |
10: 70,872,256 |
|
noncoding transcript |
Het |
| 9930021J03Rik |
T |
C |
19: 29,716,414 |
N1960S |
probably damaging |
Het |
| Abl1 |
T |
A |
2: 31,800,644 |
M706K |
probably benign |
Het |
| Abtb1 |
T |
C |
6: 88,836,554 |
T401A |
probably benign |
Het |
| Acd |
A |
G |
8: 105,700,490 |
L96P |
probably damaging |
Het |
| Arsi |
G |
A |
18: 60,916,651 |
G202E |
probably benign |
Het |
| Arsi |
T |
A |
18: 60,912,297 |
W20R |
probably damaging |
Het |
| Asic3 |
C |
T |
5: 24,413,751 |
Q14* |
probably null |
Het |
| Asxl3 |
T |
A |
18: 22,522,068 |
I1045N |
probably damaging |
Het |
| Atr |
T |
C |
9: 95,936,421 |
I2149T |
probably damaging |
Het |
| Begain |
A |
G |
12: 109,033,099 |
|
probably null |
Het |
| Brca2 |
C |
T |
5: 150,536,922 |
T554I |
possibly damaging |
Het |
| C130079G13Rik |
C |
A |
3: 59,932,580 |
Y24* |
probably null |
Het |
| C1s2 |
C |
T |
6: 124,635,682 |
V11I |
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,376,789 |
F1333L |
possibly damaging |
Het |
| Camsap2 |
T |
C |
1: 136,273,783 |
T662A |
possibly damaging |
Het |
| Cep164 |
C |
T |
9: 45,778,928 |
V1367M |
probably damaging |
Het |
| Cfap46 |
C |
A |
7: 139,639,602 |
A1316S |
probably benign |
Het |
| Cic |
T |
C |
7: 25,288,266 |
S553P |
probably damaging |
Het |
| Clcn2 |
C |
T |
16: 20,715,962 |
A12T |
probably benign |
Het |
| Clip2 |
A |
G |
5: 134,503,227 |
Y540H |
probably benign |
Het |
| Coil |
A |
G |
11: 88,982,097 |
N428S |
possibly damaging |
Het |
| Cpxm1 |
A |
C |
2: 130,395,697 |
V196G |
probably damaging |
Het |
| Cr2 |
A |
G |
1: 195,157,316 |
V601A |
probably damaging |
Het |
| Cyp3a25 |
T |
A |
5: 145,984,953 |
K390N |
probably damaging |
Het |
| Dclre1a |
T |
C |
19: 56,546,718 |
|
probably null |
Het |
| Dlg5 |
T |
C |
14: 24,149,444 |
H1464R |
probably benign |
Het |
| Dmac2 |
T |
G |
7: 25,624,792 |
M225R |
probably damaging |
Het |
| Dnah8 |
T |
C |
17: 30,731,180 |
V1991A |
possibly damaging |
Het |
| Dscam |
A |
C |
16: 96,825,581 |
V376G |
probably benign |
Het |
| Dync1li1 |
A |
G |
9: 114,709,184 |
D203G |
probably benign |
Het |
| Eva1c |
A |
G |
16: 90,866,443 |
T22A |
probably benign |
Het |
| Fam110b |
A |
G |
4: 5,799,029 |
D149G |
probably benign |
Het |
| Fras1 |
A |
T |
5: 96,770,688 |
I3528F |
probably damaging |
Het |
| Fsip1 |
T |
C |
2: 118,232,908 |
D360G |
probably damaging |
Het |
| Galnt14 |
T |
C |
17: 73,709,939 |
T41A |
probably benign |
Het |
| Gdf3 |
T |
A |
6: 122,609,962 |
Q2L |
probably benign |
Het |
| Glrp1 |
A |
G |
1: 88,509,789 |
|
probably null |
Het |
| Gm3336 |
C |
G |
8: 70,720,417 |
|
probably null |
Het |
| Gm8674 |
C |
T |
13: 49,900,808 |
|
noncoding transcript |
Het |
| Gnat1 |
A |
G |
9: 107,676,575 |
Y226H |
probably damaging |
Het |
| Grk5 |
T |
C |
19: 61,089,972 |
V489A |
probably damaging |
Het |
| H1foo |
A |
G |
6: 115,948,758 |
Y1C |
probably null |
Het |
| Ick |
T |
A |
9: 78,157,862 |
D351E |
probably benign |
Het |
| Igfbpl1 |
C |
A |
4: 45,826,406 |
A130S |
probably benign |
Het |
| Impdh1 |
T |
A |
6: 29,205,088 |
D261V |
probably benign |
Het |
| Itgal |
T |
A |
7: 127,314,060 |
S610T |
probably damaging |
Het |
| Jcad |
A |
G |
18: 4,649,293 |
T55A |
probably benign |
Het |
| Jup |
G |
A |
11: 100,374,137 |
R663* |
probably null |
Het |
| Kalrn |
C |
T |
16: 34,294,215 |
G556D |
probably damaging |
Het |
| Krt81 |
T |
C |
15: 101,460,139 |
E411G |
probably damaging |
Het |
| Lcat |
T |
C |
8: 105,939,888 |
E334G |
probably damaging |
Het |
| Lhcgr |
T |
C |
17: 88,750,157 |
E302G |
probably benign |
Het |
| Magi1 |
A |
G |
6: 93,699,639 |
V913A |
possibly damaging |
Het |
| Mrpl19 |
A |
T |
6: 81,964,079 |
|
probably null |
Het |
| Muc4 |
G |
T |
16: 32,755,933 |
|
probably benign |
Het |
| Mycbp2 |
A |
G |
14: 103,252,509 |
V953A |
possibly damaging |
Het |
| Myo3a |
G |
A |
2: 22,396,243 |
V600I |
probably benign |
Het |
| Ndufv3 |
G |
A |
17: 31,531,245 |
R467Q |
probably damaging |
Het |
| Ngef |
A |
G |
1: 87,503,264 |
|
probably null |
Het |
| Nisch |
A |
T |
14: 31,176,432 |
|
probably benign |
Het |
| Nlrp4c |
G |
A |
7: 6,066,956 |
|
probably null |
Het |
| Nup153 |
A |
T |
13: 46,713,747 |
S154T |
probably damaging |
Het |
| Obscn |
A |
G |
11: 58,994,832 |
|
probably benign |
Het |
| Olfr1247 |
G |
T |
2: 89,609,349 |
P251H |
probably damaging |
Het |
| Olfr31 |
T |
A |
14: 14,328,774 |
L221Q |
probably damaging |
Het |
| Olfr818 |
T |
C |
10: 129,945,337 |
M242V |
possibly damaging |
Het |
| Otogl |
T |
C |
10: 107,779,831 |
N1869S |
probably benign |
Het |
| Phf24 |
G |
T |
4: 42,934,661 |
C136F |
probably damaging |
Het |
| Phldb2 |
A |
T |
16: 45,826,011 |
V65E |
probably benign |
Het |
| Pkhd1 |
C |
A |
1: 20,347,457 |
G2490V |
probably damaging |
Het |
| Prl8a8 |
A |
T |
13: 27,508,450 |
M186K |
probably damaging |
Het |
| Qars |
T |
C |
9: 108,514,610 |
V70A |
probably damaging |
Het |
| Rac1 |
C |
T |
5: 143,517,225 |
V14I |
probably benign |
Het |
| Rapgef5 |
T |
A |
12: 117,688,684 |
|
probably null |
Het |
| Slc16a12 |
G |
A |
19: 34,670,878 |
T405M |
possibly damaging |
Het |
| Slc17a6 |
A |
G |
7: 51,661,546 |
Y336C |
probably damaging |
Het |
| Slc30a9 |
T |
C |
5: 67,348,052 |
L441P |
probably damaging |
Het |
| Slc45a2 |
T |
C |
15: 11,022,086 |
S305P |
probably damaging |
Het |
| Sod3 |
G |
T |
5: 52,368,162 |
V68L |
probably benign |
Het |
| Sp1 |
T |
G |
15: 102,431,003 |
S773A |
possibly damaging |
Het |
| Spen |
C |
A |
4: 141,472,785 |
G2821C |
probably damaging |
Het |
| Tagap1 |
A |
G |
17: 6,956,026 |
S424P |
probably benign |
Het |
| Tbc1d22a |
T |
C |
15: 86,235,569 |
V22A |
possibly damaging |
Het |
| Tfec |
C |
T |
6: 16,840,468 |
|
probably null |
Het |
| Thsd7a |
A |
T |
6: 12,409,042 |
|
probably null |
Het |
| Tnfsf15 |
C |
A |
4: 63,733,351 |
G112V |
probably benign |
Het |
| Tnfsf9 |
A |
G |
17: 57,105,738 |
T103A |
probably benign |
Het |
| Tnxb |
C |
T |
17: 34,692,333 |
R1537* |
probably null |
Het |
| Tpra1 |
A |
G |
6: 88,911,823 |
N329S |
probably benign |
Het |
| Ttc12 |
A |
G |
9: 49,456,884 |
F281S |
probably damaging |
Het |
| Unc79 |
A |
G |
12: 103,059,320 |
N322S |
probably damaging |
Het |
| Unk |
G |
T |
11: 116,030,442 |
|
probably benign |
Het |
| Usp4 |
G |
T |
9: 108,348,008 |
G31W |
probably damaging |
Het |
| Vcan |
G |
T |
13: 89,705,212 |
A543D |
possibly damaging |
Het |
| Vil1 |
A |
C |
1: 74,418,447 |
I80L |
probably benign |
Het |
| Vmn2r27 |
C |
T |
6: 124,231,634 |
G51S |
probably benign |
Het |
| Vpreb1 |
A |
G |
16: 16,869,071 |
|
probably null |
Het |
| Zbtb6 |
C |
T |
2: 37,429,817 |
C33Y |
probably damaging |
Het |
| Zfp330 |
A |
T |
8: 82,766,015 |
C189* |
probably null |
Het |
| Zfp942 |
T |
A |
17: 21,928,541 |
H369L |
probably damaging |
Het |
| Zfp943 |
T |
A |
17: 21,992,380 |
I149K |
probably benign |
Het |
| Zfyve19 |
G |
A |
2: 119,211,535 |
V162M |
probably benign |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1851:Dennd4a
|
UTSW |
9 |
64,862,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACAGTGTTACGCTGGCGAG -3'
(R):5'- AGTTCACACTGGACTTAGGGAAAC -3'
Sequencing Primer
(F):5'- TGGCGAGCTGGGAAACTTC -3'
(R):5'- GAGTGTCTAAGAATGCCCATTGCTC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation