Mutagenetix > Incidental Mutation

Incidental Mutation 'R1829:Dnah12'

207151

Institutional Source

Beutler Lab

Gene Symbol

Dnah12

Ensembl Gene

ENSMUSG00000021879

Gene Name

dynein, axonemal, heavy chain 12

Synonyms

DHC3, Hdhc3, HL-19, Dnahc7l, 4921531P07Rik, LOC380889, DLP12, HL19, Dnahc12

MMRRC Submission

039856-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.196) question?

Stock #

R1829 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

26693274-26891703 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 26800075 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Lysine at position 1948 (N1948K)

Ref Sequence

ENSEMBL: ENSMUSP00000022433 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022433]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000022433
AA Change: N1948K

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000022433
Gene: ENSMUSG00000021879
AA Change: N1948K

Domain	Start	End	E-Value	Type
low complexity region	127	140	N/A	INTRINSIC
coiled coil region	588	666	N/A	INTRINSIC
Pfam:DHC_N2	676	1113	1.1e-147	PFAM
AAA	1268	1407	1.15e0	SMART
Pfam:AAA_5	1552	1695	1.5e-7	PFAM
Blast:AAA	1709	1827	2e-24	BLAST
Blast:AAA	1848	1898	1e-16	BLAST
AAA	1903	2051	5.42e-4	SMART
Pfam:AAA_8	2238	2316	2e-18	PFAM

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.1%
20x: 91.7%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 113 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aars1	A	T	8: 111,042,706 (GRCm38)	D287V	probably damaging	Het
Abca12	A	G	1: 71,295,029 (GRCm38)	C1105R	probably benign	Het
Abca8b	T	A	11: 109,942,341 (GRCm38)	N1178Y	probably damaging	Het
Abhd12	A	G	2: 150,843,398 (GRCm38)	L189P	probably damaging	Het
Acap2	G	T	16: 31,110,934 (GRCm38)	N435K	probably damaging	Het
Adam6b	G	T	12: 113,489,925 (GRCm38)	G121C	probably damaging	Het
Adgrb1	C	A	15: 74,580,586 (GRCm38)	C200*	probably null	Het
Agbl5	T	C	5: 30,903,064 (GRCm38)	S730P	possibly damaging	Het
Ahsg	G	A	16: 22,892,328 (GRCm38)		probably benign	Het
Aldh9a1	A	T	1: 167,361,854 (GRCm38)	K390N	probably benign	Het
Alpk2	T	A	18: 65,294,094 (GRCm38)	H1857L	possibly damaging	Het
Apip	T	A	2: 103,088,662 (GRCm38)	N102K	probably benign	Het
Asxl2	T	C	12: 3,457,125 (GRCm38)	S106P	probably damaging	Het
Atp2b2	G	T	6: 113,773,368 (GRCm38)	R677S	probably damaging	Het
Barhl1	A	C	2: 28,909,845 (GRCm38)	M256R	probably damaging	Het
Cacnb2	A	T	2: 14,985,964 (GRCm38)	Q619L	possibly damaging	Het
Ccdc137	C	T	11: 120,458,212 (GRCm38)	P23L	probably benign	Het
Cdh11	A	T	8: 102,634,641 (GRCm38)	N688K	possibly damaging	Het
Cdh18	C	T	15: 23,173,852 (GRCm38)	P51S	probably damaging	Het
Cdin1	G	T	2: 115,642,692 (GRCm38)	R101L	possibly damaging	Het
Cfhr1	A	T	1: 139,553,600 (GRCm38)	Y181N	probably damaging	Het
Chmp3	A	G	6: 71,560,939 (GRCm38)	D50G	probably benign	Het
Crem	T	C	18: 3,295,037 (GRCm38)		probably null	Het
Cyb561a3	G	A	19: 10,582,393 (GRCm38)	W27*	probably null	Het
Cyp2d12	C	A	15: 82,558,056 (GRCm38)	N297K	possibly damaging	Het
Dclk2	C	T	3: 86,805,639 (GRCm38)	R503Q	possibly damaging	Het
Dsp	T	G	13: 38,193,195 (GRCm38)	L1652R	probably damaging	Het
Dstyk	G	A	1: 132,449,595 (GRCm38)	S66N	probably benign	Het
Ehhadh	T	C	16: 21,762,178 (GRCm38)	E688G	probably damaging	Het
Emsy	G	T	7: 98,602,730 (GRCm38)	H688N	possibly damaging	Het
Emsy	T	A	7: 98,602,729 (GRCm38)	H688L	possibly damaging	Het
Endod1	A	G	9: 14,356,926 (GRCm38)	L421P	probably damaging	Het
Fam222b	C	T	11: 78,155,035 (GRCm38)	P346L	probably damaging	Het
Fam3c	G	A	6: 22,309,437 (GRCm38)	R182W	probably damaging	Het
Gck	T	C	11: 5,910,984 (GRCm38)	D29G	probably damaging	Het
Gm10320	C	A	13: 98,489,699 (GRCm38)	R59L	probably damaging	Het
Gm11127	G	T	17: 36,058,004 (GRCm38)	F61L	probably damaging	Het
Gm21798	C	T	15: 64,817,826 (GRCm38)		probably benign	Het
Gm9376	A	G	14: 118,267,545 (GRCm38)	T130A	possibly damaging	Het
Gpr153	T	A	4: 152,282,392 (GRCm38)	I334N	possibly damaging	Het
Greb1l	T	C	18: 10,509,314 (GRCm38)	L542P	probably damaging	Het
Hacl1	T	C	14: 31,640,534 (GRCm38)	E52G	probably benign	Het
Ice2	A	G	9: 69,407,353 (GRCm38)	Y128C	probably damaging	Het
Ikzf2	T	A	1: 69,542,287 (GRCm38)	I121L	probably benign	Het
Ipcef1	C	T	10: 6,919,900 (GRCm38)	A167T	probably benign	Het
Jakmip2	T	A	18: 43,582,080 (GRCm38)	D127V	possibly damaging	Het
Jph4	T	C	14: 55,114,911 (GRCm38)	T122A	probably damaging	Het
Kcns2	A	G	15: 34,838,803 (GRCm38)	E104G	probably damaging	Het
Lars2	A	C	9: 123,431,917 (GRCm38)	R384S	probably benign	Het
Lsmem1	G	T	12: 40,185,409 (GRCm38)	H3N	possibly damaging	Het
Lsmem1	T	A	12: 40,185,408 (GRCm38)	H3L	possibly damaging	Het
Ly6g2	T	G	15: 75,216,756 (GRCm38)		probably null	Het
Mfhas1	C	G	8: 35,590,248 (GRCm38)	R626G	probably benign	Het
Mfhas1	A	C	8: 35,590,068 (GRCm38)	S566R	probably benign	Het
Mgam	A	G	6: 40,666,892 (GRCm38)	T585A	probably damaging	Het
Mmp25	T	C	17: 23,640,023 (GRCm38)	K185E	probably benign	Het
Mtch1	T	C	17: 29,338,776 (GRCm38)	I243V	probably damaging	Het
Mtcp1	A	T	X: 75,411,665 (GRCm38)	Y25*	probably null	Het
Mybl2	A	G	2: 163,059,583 (GRCm38)	T35A	probably benign	Het
Myh11	T	C	16: 14,223,880 (GRCm38)	E736G	probably damaging	Het
Myh2	T	C	11: 67,176,559 (GRCm38)	I224T	probably damaging	Het
Mymx	T	C	17: 45,601,833 (GRCm38)		probably benign	Het
Nek10	A	G	14: 14,863,454 (GRCm38)		probably null	Het
Nsd1	A	T	13: 55,246,369 (GRCm38)	K697N	probably damaging	Het
Nynrin	A	G	14: 55,872,947 (GRCm38)	D1837G	possibly damaging	Het
Or14j4	G	A	17: 37,610,277 (GRCm38)	T158I	probably benign	Het
Or2ag2b	A	G	7: 106,819,007 (GRCm38)	H308R	probably benign	Het
Or52s1	A	T	7: 103,211,886 (GRCm38)	T9S	probably benign	Het
Or5p81	T	A	7: 108,667,644 (GRCm38)	I76N	probably benign	Het
Or6k4	T	A	1: 174,137,194 (GRCm38)	I150N	probably benign	Het
Pgap6	T	C	17: 26,122,220 (GRCm38)	Y766H	probably damaging	Het
Phf19	T	C	2: 34,911,769 (GRCm38)	T10A	probably benign	Het
Pkd1	A	T	17: 24,565,584 (GRCm38)	H368L	probably benign	Het
Plscr2	A	G	9: 92,290,755 (GRCm38)	R156G	probably damaging	Het
Ppp1r42	G	A	1: 10,000,086 (GRCm38)	R61C	probably benign	Het
Pptc7	T	G	5: 122,313,616 (GRCm38)	V45G	probably damaging	Het
Prlhr	G	A	19: 60,467,429 (GRCm38)	T233I	probably damaging	Het
Prr23a4	T	A	9: 98,903,393 (GRCm38)	I37N	possibly damaging	Het
Reps1	C	T	10: 18,107,714 (GRCm38)	T435I	probably damaging	Het
Ret	T	A	6: 118,153,951 (GRCm38)	T1084S	probably damaging	Het
Rgl2	T	A	17: 33,933,621 (GRCm38)	M402K	probably benign	Het
Rp2	A	G	X: 20,376,915 (GRCm38)	K43R	probably benign	Het
Rundc3b	A	T	5: 8,579,117 (GRCm38)	W95R	probably damaging	Het
Samd9l	T	C	6: 3,375,107 (GRCm38)	D718G	possibly damaging	Het
Scnn1b	G	A	7: 121,902,845 (GRCm38)	R242H	probably benign	Het
Smad4	G	T	18: 73,641,894 (GRCm38)	Q445K	probably benign	Het
Smchd1	G	T	17: 71,370,337 (GRCm38)	P1486T	probably damaging	Het
Snx25	G	T	8: 46,035,632 (GRCm38)	N895K	possibly damaging	Het
Sox2	A	G	3: 34,650,741 (GRCm38)	D109G	probably damaging	Het
Stfa2	A	T	16: 36,405,202 (GRCm38)	N38K	probably damaging	Het
Stfa2	C	A	16: 36,405,211 (GRCm38)	E35D	possibly damaging	Het
Stfa3	A	G	16: 36,450,661 (GRCm38)	L87P	probably damaging	Het
Strbp	T	C	2: 37,640,909 (GRCm38)	D111G	possibly damaging	Het
Supt20	C	A	3: 54,727,658 (GRCm38)		probably benign	Het
Svep1	A	G	4: 58,096,310 (GRCm38)	Y1437H	possibly damaging	Het
Tbx4	T	A	11: 85,911,920 (GRCm38)		probably null	Het
Tmem117	A	T	15: 95,094,551 (GRCm38)	N364I	probably damaging	Het
Trat1	T	C	16: 48,761,379 (GRCm38)	E45G	probably damaging	Het
Trpc2	G	A	7: 102,084,119 (GRCm38)	D92N	probably damaging	Het
Trpm1	G	A	7: 64,226,782 (GRCm38)	D528N	probably damaging	Het
Ttll9	A	G	2: 153,000,236 (GRCm38)	S337G	possibly damaging	Het
Utrn	A	T	10: 12,475,274 (GRCm38)	I355N	probably damaging	Het
Vangl1	A	G	3: 102,163,466 (GRCm38)	S385P	probably benign	Het
Vmn1r209	A	G	13: 22,806,239 (GRCm38)	S94P	possibly damaging	Het
Vmn2r28	T	A	7: 5,493,811 (GRCm38)	Q14L	probably benign	Het
Vps45	A	G	3: 96,047,245 (GRCm38)		probably null	Het
Wdr48	T	C	9: 119,904,330 (GRCm38)	V81A	probably benign	Het
Xpnpep2	A	G	X: 48,125,353 (GRCm38)	N476S	probably benign	Het
Zbtb41	A	T	1: 139,446,922 (GRCm38)	K707*	probably null	Het
Zfp442	A	C	2: 150,409,063 (GRCm38)	C306W	probably damaging	Het
Zfp811	T	C	17: 32,798,142 (GRCm38)	N307S	possibly damaging	Het
Zfp976	A	G	7: 42,616,311 (GRCm38)	W17R	probably damaging	Het
Zyg11b	T	C	4: 108,266,093 (GRCm38)	T226A	possibly damaging	Het

Other mutations in Dnah12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01412:Dnah12	APN	14	26,771,005 (GRCm38)	missense	probably damaging	1.00
IGL01602:Dnah12	APN	14	26,710,275 (GRCm38)	splice site	probably benign
IGL01681:Dnah12	APN	14	26,722,160 (GRCm38)	missense	probably benign
IGL02082:Dnah12	APN	14	26,707,162 (GRCm38)	missense	possibly damaging	0.79
IGL02140:Dnah12	APN	14	26,716,577 (GRCm38)	missense	probably benign	0.20
IGL02170:Dnah12	APN	14	26,773,112 (GRCm38)	missense	probably damaging	0.99
IGL02174:Dnah12	APN	14	26,706,917 (GRCm38)	missense	probably benign	0.00
IGL02367:Dnah12	APN	14	26,709,161 (GRCm38)	missense	probably benign	0.30
IGL02418:Dnah12	APN	14	26,773,722 (GRCm38)	missense	probably damaging	1.00
IGL03039:Dnah12	APN	14	26,724,512 (GRCm38)	missense	probably benign	0.02
IGL03066:Dnah12	APN	14	26,697,398 (GRCm38)	missense	probably benign	0.06
drippings	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
grueben	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
BB010:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
BB020:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
F5770:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
FR4304:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4340:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4342:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
FR4589:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
IGL03055:Dnah12	UTSW	14	26,872,740 (GRCm38)	missense	probably damaging	1.00
LCD18:Dnah12	UTSW	14	26,849,385 (GRCm38)	missense	probably damaging	1.00
R0003:Dnah12	UTSW	14	26,772,644 (GRCm38)	missense	probably damaging	1.00
R0110:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0302:Dnah12	UTSW	14	26,799,999 (GRCm38)	missense	probably damaging	1.00
R0355:Dnah12	UTSW	14	26,706,117 (GRCm38)	splice site	probably null
R0364:Dnah12	UTSW	14	26,724,473 (GRCm38)	missense	probably benign	0.10
R0469:Dnah12	UTSW	14	26,798,899 (GRCm38)	missense	probably damaging	1.00
R0558:Dnah12	UTSW	14	26,709,310 (GRCm38)	missense	probably benign	0.00
R0709:Dnah12	UTSW	14	26,884,265 (GRCm38)	splice site	probably benign
R0734:Dnah12	UTSW	14	26,800,013 (GRCm38)	missense	probably benign	0.00
R1273:Dnah12	UTSW	14	26,739,220 (GRCm38)	nonsense	probably null
R1496:Dnah12	UTSW	14	26,710,248 (GRCm38)	missense	probably benign
R1503:Dnah12	UTSW	14	26,773,692 (GRCm38)	missense	probably damaging	1.00
R1535:Dnah12	UTSW	14	26,816,322 (GRCm38)	missense	possibly damaging	0.91
R1608:Dnah12	UTSW	14	26,766,190 (GRCm38)	missense	probably damaging	1.00
R1682:Dnah12	UTSW	14	26,778,883 (GRCm38)	missense	possibly damaging	0.71
R1758:Dnah12	UTSW	14	26,766,114 (GRCm38)	missense	probably benign	0.02
R1826:Dnah12	UTSW	14	26,711,019 (GRCm38)	missense	probably benign	0.01
R1829:Dnah12	UTSW	14	26,773,023 (GRCm38)	missense	probably damaging	1.00
R1862:Dnah12	UTSW	14	26,709,257 (GRCm38)	missense	probably benign	0.30
R1862:Dnah12	UTSW	14	26,697,398 (GRCm38)	missense	probably benign	0.06
R1913:Dnah12	UTSW	14	26,792,264 (GRCm38)	splice site	probably null
R1933:Dnah12	UTSW	14	26,734,495 (GRCm38)	missense	probably damaging	0.98
R2006:Dnah12	UTSW	14	26,814,459 (GRCm38)	missense	possibly damaging	0.95
R2045:Dnah12	UTSW	14	26,781,528 (GRCm38)	missense	probably null	1.00
R2113:Dnah12	UTSW	14	26,766,141 (GRCm38)	missense	probably damaging	1.00
R2125:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2126:Dnah12	UTSW	14	26,724,458 (GRCm38)	nonsense	probably null
R2207:Dnah12	UTSW	14	26,781,787 (GRCm38)	missense	probably damaging	0.99
R2213:Dnah12	UTSW	14	26,739,330 (GRCm38)	missense	probably benign	0.06
R2511:Dnah12	UTSW	14	26,769,950 (GRCm38)	missense	possibly damaging	0.65
R2875:Dnah12	UTSW	14	26,876,950 (GRCm38)	missense	probably benign	0.05
R2875:Dnah12	UTSW	14	26,693,470 (GRCm38)	missense	probably benign	0.04
R3551:Dnah12	UTSW	14	26,770,972 (GRCm38)	missense	probably benign	0.01
R3713:Dnah12	UTSW	14	26,812,790 (GRCm38)	missense	probably benign
R3729:Dnah12	UTSW	14	26,706,065 (GRCm38)	missense	probably benign	0.02
R3799:Dnah12	UTSW	14	26,770,923 (GRCm38)	missense	probably damaging	1.00
R3846:Dnah12	UTSW	14	26,710,211 (GRCm38)	missense	probably benign	0.00
R3892:Dnah12	UTSW	14	26,856,616 (GRCm38)	missense	probably benign	0.03
R3921:Dnah12	UTSW	14	26,771,051 (GRCm38)	missense	probably damaging	1.00
R3940:Dnah12	UTSW	14	26,723,599 (GRCm38)	missense	probably benign
R4065:Dnah12	UTSW	14	26,770,448 (GRCm38)	missense	probably benign	0.02
R4113:Dnah12	UTSW	14	26,693,567 (GRCm38)	missense	probably damaging	0.98
R4249:Dnah12	UTSW	14	26,709,186 (GRCm38)	missense	possibly damaging	0.70
R4259:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4260:Dnah12	UTSW	14	26,798,926 (GRCm38)	missense	probably benign	0.01
R4348:Dnah12	UTSW	14	26,814,541 (GRCm38)	missense	possibly damaging	0.94
R4457:Dnah12	UTSW	14	26,815,507 (GRCm38)	missense	probably damaging	1.00
R4490:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4491:Dnah12	UTSW	14	26,734,603 (GRCm38)	missense	possibly damaging	0.67
R4494:Dnah12	UTSW	14	26,871,855 (GRCm38)	missense	probably damaging	0.99
R4523:Dnah12	UTSW	14	26,876,958 (GRCm38)	missense	possibly damaging	0.83
R4523:Dnah12	UTSW	14	26,770,022 (GRCm38)	missense	probably damaging	0.97
R4546:Dnah12	UTSW	14	26,773,014 (GRCm38)	missense	probably damaging	1.00
R4584:Dnah12	UTSW	14	26,772,594 (GRCm38)	missense	probably damaging	1.00
R4624:Dnah12	UTSW	14	26,735,758 (GRCm38)	missense	possibly damaging	0.82
R4689:Dnah12	UTSW	14	26,706,839 (GRCm38)	missense	probably benign	0.00
R4727:Dnah12	UTSW	14	26,872,317 (GRCm38)	missense	probably damaging	1.00
R4732:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4733:Dnah12	UTSW	14	26,781,784 (GRCm38)	missense	probably damaging	1.00
R4851:Dnah12	UTSW	14	26,716,629 (GRCm38)	nonsense	probably null
R4879:Dnah12	UTSW	14	26,718,046 (GRCm38)	critical splice donor site	probably null
R4893:Dnah12	UTSW	14	26,710,170 (GRCm38)	missense	possibly damaging	0.66
R4915:Dnah12	UTSW	14	26,734,570 (GRCm38)	missense	probably damaging	1.00
R4927:Dnah12	UTSW	14	26,861,805 (GRCm38)	nonsense	probably null
R4939:Dnah12	UTSW	14	26,891,524 (GRCm38)	missense	probably damaging	1.00
R4962:Dnah12	UTSW	14	26,716,700 (GRCm38)	missense	probably benign	0.00
R5011:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5013:Dnah12	UTSW	14	26,710,171 (GRCm38)	missense	probably benign	0.03
R5043:Dnah12	UTSW	14	26,884,190 (GRCm38)	missense	probably damaging	1.00
R5049:Dnah12	UTSW	14	26,735,697 (GRCm38)	missense	probably benign	0.09
R5122:Dnah12	UTSW	14	26,718,000 (GRCm38)	missense	probably benign	0.00
R5135:Dnah12	UTSW	14	26,770,477 (GRCm38)	missense	probably damaging	0.99
R5149:Dnah12	UTSW	14	26,850,926 (GRCm38)	nonsense	probably null
R5154:Dnah12	UTSW	14	26,849,363 (GRCm38)	missense	probably benign	0.12
R5206:Dnah12	UTSW	14	26,769,985 (GRCm38)	missense	probably damaging	1.00
R5307:Dnah12	UTSW	14	26,693,486 (GRCm38)	missense	possibly damaging	0.49
R5330:Dnah12	UTSW	14	26,773,830 (GRCm38)	missense	probably damaging	1.00
R5335:Dnah12	UTSW	14	26,879,738 (GRCm38)	missense	probably damaging	1.00
R5339:Dnah12	UTSW	14	26,814,537 (GRCm38)	missense	possibly damaging	0.83
R5354:Dnah12	UTSW	14	26,774,342 (GRCm38)	splice site	probably null
R5389:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R5434:Dnah12	UTSW	14	26,859,299 (GRCm38)	missense	probably damaging	1.00
R5466:Dnah12	UTSW	14	26,771,050 (GRCm38)	missense	probably damaging	1.00
R5655:Dnah12	UTSW	14	26,710,269 (GRCm38)	missense	probably benign	0.01
R5681:Dnah12	UTSW	14	26,815,495 (GRCm38)	missense	probably benign	0.32
R5824:Dnah12	UTSW	14	26,770,518 (GRCm38)	critical splice donor site	probably null
R5863:Dnah12	UTSW	14	26,854,921 (GRCm38)	missense	probably damaging	1.00
R5890:Dnah12	UTSW	14	26,706,884 (GRCm38)	missense	probably benign	0.09
R5912:Dnah12	UTSW	14	26,770,008 (GRCm38)	nonsense	probably null
R5916:Dnah12	UTSW	14	26,706,918 (GRCm38)	missense	possibly damaging	0.92
R5941:Dnah12	UTSW	14	26,706,867 (GRCm38)	missense	probably benign	0.00
R5987:Dnah12	UTSW	14	26,886,871 (GRCm38)	missense	possibly damaging	0.54
R5992:Dnah12	UTSW	14	26,697,341 (GRCm38)	missense	probably benign	0.04
R6132:Dnah12	UTSW	14	26,717,911 (GRCm38)	missense	probably damaging	1.00
R6136:Dnah12	UTSW	14	26,875,270 (GRCm38)	missense	probably damaging	0.99
R6158:Dnah12	UTSW	14	26,773,685 (GRCm38)	missense	possibly damaging	0.95
R6183:Dnah12	UTSW	14	26,861,769 (GRCm38)	missense	probably damaging	1.00
R6191:Dnah12	UTSW	14	26,710,257 (GRCm38)	missense	probably benign	0.03
R6235:Dnah12	UTSW	14	26,854,804 (GRCm38)	missense	probably damaging	1.00
R6277:Dnah12	UTSW	14	26,770,482 (GRCm38)	missense	probably damaging	1.00
R6332:Dnah12	UTSW	14	26,717,974 (GRCm38)	missense	probably damaging	0.99
R6334:Dnah12	UTSW	14	26,706,834 (GRCm38)	missense	possibly damaging	0.51
R6443:Dnah12	UTSW	14	26,878,051 (GRCm38)	missense	probably benign	0.06
R6480:Dnah12	UTSW	14	26,872,455 (GRCm38)	missense	probably damaging	1.00
R6530:Dnah12	UTSW	14	26,735,710 (GRCm38)	missense	probably damaging	1.00
R6678:Dnah12	UTSW	14	26,735,692 (GRCm38)	missense	probably damaging	1.00
R6709:Dnah12	UTSW	14	26,872,749 (GRCm38)	missense	probably damaging	1.00
R6724:Dnah12	UTSW	14	26,796,223 (GRCm38)	missense	probably benign	0.02
R6745:Dnah12	UTSW	14	26,707,228 (GRCm38)	missense	probably damaging	0.99
R6788:Dnah12	UTSW	14	26,801,513 (GRCm38)	missense	probably damaging	0.99
R6894:Dnah12	UTSW	14	26,735,749 (GRCm38)	missense	probably damaging	1.00
R6912:Dnah12	UTSW	14	26,878,079 (GRCm38)	missense	probably damaging	1.00
R6982:Dnah12	UTSW	14	26,799,076 (GRCm38)	splice site	probably null
R7001:Dnah12	UTSW	14	26,879,724 (GRCm38)	missense	probably damaging	0.99
R7002:Dnah12	UTSW	14	26,876,998 (GRCm38)	missense	probably damaging	1.00
R7017:Dnah12	UTSW	14	26,735,680 (GRCm38)	missense	probably benign
R7107:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7108:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7121:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7122:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7135:Dnah12	UTSW	14	26,801,413 (GRCm38)	missense	probably damaging	0.99
R7135:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7150:Dnah12	UTSW	14	26,861,732 (GRCm38)	missense	probably damaging	0.99
R7188:Dnah12	UTSW	14	26,814,413 (GRCm38)	missense	probably benign	0.04
R7201:Dnah12	UTSW	14	26,814,622 (GRCm38)	missense	probably benign	0.08
R7202:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7204:Dnah12	UTSW	14	26,781,485 (GRCm38)	missense	probably damaging	0.99
R7204:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7205:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7206:Dnah12	UTSW	14	26,778,912 (GRCm38)	critical splice donor site	probably null
R7219:Dnah12	UTSW	14	26,854,880 (GRCm38)	missense	probably damaging	0.99
R7337:Dnah12	UTSW	14	26,766,577 (GRCm38)	splice site	probably null
R7339:Dnah12	UTSW	14	26,872,320 (GRCm38)	missense	probably benign
R7363:Dnah12	UTSW	14	26,724,611 (GRCm38)	missense	probably benign
R7426:Dnah12	UTSW	14	26,724,626 (GRCm38)	missense	probably benign	0.01
R7472:Dnah12	UTSW	14	26,856,635 (GRCm38)	missense	probably benign	0.01
R7579:Dnah12	UTSW	14	26,770,503 (GRCm38)	missense	probably benign	0.05
R7655:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7656:Dnah12	UTSW	14	26,859,316 (GRCm38)	missense	probably benign	0.21
R7694:Dnah12	UTSW	14	26,781,380 (GRCm38)	missense	probably damaging	1.00
R7730:Dnah12	UTSW	14	26,785,933 (GRCm38)	missense	probably damaging	1.00
R7837:Dnah12	UTSW	14	26,796,219 (GRCm38)	missense	probably benign	0.01
R7855:Dnah12	UTSW	14	26,829,329 (GRCm38)	missense	probably benign	0.14
R7870:Dnah12	UTSW	14	26,856,529 (GRCm38)	missense	probably benign	0.00
R7920:Dnah12	UTSW	14	26,856,542 (GRCm38)	missense	possibly damaging	0.58
R7933:Dnah12	UTSW	14	26,766,115 (GRCm38)	missense	probably benign	0.00
R7956:Dnah12	UTSW	14	26,709,272 (GRCm38)	missense	probably damaging	0.96
R8192:Dnah12	UTSW	14	26,706,881 (GRCm38)	missense	probably benign
R8263:Dnah12	UTSW	14	26,891,464 (GRCm38)	missense	noncoding transcript
R8287:Dnah12	UTSW	14	26,812,603 (GRCm38)	missense	probably benign
R8336:Dnah12	UTSW	14	26,711,065 (GRCm38)	missense	probably benign	0.01
R8362:Dnah12	UTSW	14	26,854,831 (GRCm38)	missense	probably damaging	1.00
R8392:Dnah12	UTSW	14	26,885,912 (GRCm38)	missense	probably benign
R8458:Dnah12	UTSW	14	26,826,892 (GRCm38)	critical splice acceptor site	probably null
R8481:Dnah12	UTSW	14	26,853,796 (GRCm38)	missense	probably benign	0.02
R8551:Dnah12	UTSW	14	26,774,270 (GRCm38)	missense	probably damaging	0.97
R8669:Dnah12	UTSW	14	26,830,625 (GRCm38)	splice site	probably benign
R8698:Dnah12	UTSW	14	26,707,263 (GRCm38)	missense	probably benign	0.02
R8709:Dnah12	UTSW	14	26,693,602 (GRCm38)	missense	probably benign	0.00
R8778:Dnah12	UTSW	14	26,734,563 (GRCm38)	missense	probably benign	0.29
R9049:Dnah12	UTSW	14	26,722,120 (GRCm38)	missense	probably benign	0.00
R9087:Dnah12	UTSW	14	26,824,546 (GRCm38)	missense	probably damaging	1.00
R9099:Dnah12	UTSW	14	26,770,368 (GRCm38)	missense	probably benign	0.31
R9153:Dnah12	UTSW	14	26,814,612 (GRCm38)	missense	probably damaging	1.00
R9177:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9214:Dnah12	UTSW	14	26,723,905 (GRCm38)	missense	probably benign	0.02
R9268:Dnah12	UTSW	14	26,849,298 (GRCm38)	missense	possibly damaging	0.84
R9274:Dnah12	UTSW	14	26,815,417 (GRCm38)	missense	probably benign	0.00
R9293:Dnah12	UTSW	14	26,773,059 (GRCm38)	missense	probably benign
R9322:Dnah12	UTSW	14	26,770,977 (GRCm38)	missense	possibly damaging	0.75
R9353:Dnah12	UTSW	14	26,856,550 (GRCm38)	missense	probably damaging	1.00
R9506:Dnah12	UTSW	14	26,792,211 (GRCm38)	missense	probably benign	0.00
R9518:Dnah12	UTSW	14	26,773,756 (GRCm38)	missense	probably damaging	1.00
R9524:Dnah12	UTSW	14	26,850,537 (GRCm38)	missense	probably null	0.91
R9562:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9565:Dnah12	UTSW	14	26,875,324 (GRCm38)	missense	possibly damaging	0.58
R9573:Dnah12	UTSW	14	26,693,464 (GRCm38)	missense	probably benign
R9581:Dnah12	UTSW	14	26,770,028 (GRCm38)	missense	probably damaging	1.00
R9689:Dnah12	UTSW	14	26,868,914 (GRCm38)	missense	probably null	1.00
R9727:Dnah12	UTSW	14	26,801,553 (GRCm38)	nonsense	probably null
V7580:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
V7581:Dnah12	UTSW	14	26,773,093 (GRCm38)	missense	possibly damaging	0.95
X0018:Dnah12	UTSW	14	26,814,480 (GRCm38)	missense	probably damaging	1.00
X0027:Dnah12	UTSW	14	26,816,288 (GRCm38)	missense	probably damaging	1.00
X0065:Dnah12	UTSW	14	26,814,645 (GRCm38)	missense	possibly damaging	0.93
Z1177:Dnah12	UTSW	14	26,875,215 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GGGCTTTATTAGTCTTTCATGCAC -3'
(R):5'- TGAATATTCAATTATGCCCACCCAC -3'

Sequencing Primer
(F):5'- AAAATGCATTTGTACTTCCTTCCATC -3'
(R):5'- ACCACCCTTGTGTGCACAC -3'

Posted On

2014-06-23