Incidental Mutation 'R1829:Greb1l'
| ID |
207187 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Greb1l
|
| Ensembl Gene |
ENSMUSG00000042942 |
| Gene Name |
growth regulation by estrogen in breast cancer-like |
| Synonyms |
mKIAA4095, AK220484 |
| MMRRC Submission |
039856-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1829 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
10325177-10562940 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 10509314 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 542
(L542P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049003
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048977]
[ENSMUST00000172532]
[ENSMUST00000172680]
|
| AlphaFold |
B9EJV3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000048977
AA Change: L542P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000049003
Gene: ENSMUSG00000042942
AA Change: L542P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:GREB1
|
1 |
1172 |
N/A |
PFAM |
|
Pfam:GREB1
|
1154 |
1913 |
N/A |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172532
|
| SMART Domains |
Protein: ENSMUSP00000134090
Gene: ENSMUSG00000042942
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
83 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
301 |
N/A |
INTRINSIC |
|
low complexity region
|
606 |
617 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172680
|
| SMART Domains |
Protein: ENSMUSP00000134314
Gene: ENSMUSG00000042942
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
116 |
129 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000174553
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 91.7%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(5) : Targeted, other(2) Gene trapped(3) |
| Other mutations in this stock |
Total: 114 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aars1 |
A |
T |
8: 111,769,338 (GRCm39) |
D287V |
probably damaging |
Het |
| Abca12 |
A |
G |
1: 71,334,188 (GRCm39) |
C1105R |
probably benign |
Het |
| Abca8b |
T |
A |
11: 109,833,167 (GRCm39) |
N1178Y |
probably damaging |
Het |
| Abhd12 |
A |
G |
2: 150,685,318 (GRCm39) |
L189P |
probably damaging |
Het |
| Acap2 |
G |
T |
16: 30,929,752 (GRCm39) |
N435K |
probably damaging |
Het |
| Adam6b |
G |
T |
12: 113,453,545 (GRCm39) |
G121C |
probably damaging |
Het |
| Adgrb1 |
C |
A |
15: 74,452,435 (GRCm39) |
C200* |
probably null |
Het |
| Agbl5 |
T |
C |
5: 31,060,408 (GRCm39) |
S730P |
possibly damaging |
Het |
| Ahsg |
G |
A |
16: 22,711,078 (GRCm39) |
|
probably benign |
Het |
| Aldh9a1 |
A |
T |
1: 167,189,423 (GRCm39) |
K390N |
probably benign |
Het |
| Alpk2 |
T |
A |
18: 65,427,165 (GRCm39) |
H1857L |
possibly damaging |
Het |
| Apip |
T |
A |
2: 102,919,007 (GRCm39) |
N102K |
probably benign |
Het |
| Asxl2 |
T |
C |
12: 3,507,125 (GRCm39) |
S106P |
probably damaging |
Het |
| Atp2b2 |
G |
T |
6: 113,750,329 (GRCm39) |
R677S |
probably damaging |
Het |
| Barhl1 |
A |
C |
2: 28,799,857 (GRCm39) |
M256R |
probably damaging |
Het |
| Cacnb2 |
A |
T |
2: 14,990,775 (GRCm39) |
Q619L |
possibly damaging |
Het |
| Ccdc137 |
C |
T |
11: 120,349,038 (GRCm39) |
P23L |
probably benign |
Het |
| Cdh11 |
A |
T |
8: 103,361,273 (GRCm39) |
N688K |
possibly damaging |
Het |
| Cdh18 |
C |
T |
15: 23,173,938 (GRCm39) |
P51S |
probably damaging |
Het |
| Cdin1 |
G |
T |
2: 115,473,173 (GRCm39) |
R101L |
possibly damaging |
Het |
| Cfhr1 |
A |
T |
1: 139,481,338 (GRCm39) |
Y181N |
probably damaging |
Het |
| Chmp3 |
A |
G |
6: 71,537,923 (GRCm39) |
D50G |
probably benign |
Het |
| Crem |
T |
C |
18: 3,295,037 (GRCm39) |
|
probably null |
Het |
| Cyb561a3 |
G |
A |
19: 10,559,757 (GRCm39) |
W27* |
probably null |
Het |
| Cyp2d12 |
C |
A |
15: 82,442,257 (GRCm39) |
N297K |
possibly damaging |
Het |
| Dclk2 |
C |
T |
3: 86,712,946 (GRCm39) |
R503Q |
possibly damaging |
Het |
| Dnah12 |
T |
A |
14: 26,522,032 (GRCm39) |
N1948K |
probably damaging |
Het |
| Dnah12 |
T |
C |
14: 26,494,980 (GRCm39) |
L1346P |
probably damaging |
Het |
| Dsp |
T |
G |
13: 38,377,171 (GRCm39) |
L1652R |
probably damaging |
Het |
| Dstyk |
G |
A |
1: 132,377,333 (GRCm39) |
S66N |
probably benign |
Het |
| Ehhadh |
T |
C |
16: 21,580,928 (GRCm39) |
E688G |
probably damaging |
Het |
| Emsy |
G |
T |
7: 98,251,937 (GRCm39) |
H688N |
possibly damaging |
Het |
| Emsy |
T |
A |
7: 98,251,936 (GRCm39) |
H688L |
possibly damaging |
Het |
| Endod1 |
A |
G |
9: 14,268,222 (GRCm39) |
L421P |
probably damaging |
Het |
| Fam222b |
C |
T |
11: 78,045,861 (GRCm39) |
P346L |
probably damaging |
Het |
| Fam3c |
G |
A |
6: 22,309,436 (GRCm39) |
R182W |
probably damaging |
Het |
| Gck |
T |
C |
11: 5,860,984 (GRCm39) |
D29G |
probably damaging |
Het |
| Gm10320 |
C |
A |
13: 98,626,207 (GRCm39) |
R59L |
probably damaging |
Het |
| Gm21798 |
C |
T |
15: 64,689,675 (GRCm39) |
|
probably benign |
Het |
| Gm9376 |
A |
G |
14: 118,504,957 (GRCm39) |
T130A |
possibly damaging |
Het |
| Gpr153 |
T |
A |
4: 152,366,849 (GRCm39) |
I334N |
possibly damaging |
Het |
| H2-T15 |
G |
T |
17: 36,368,896 (GRCm39) |
F61L |
probably damaging |
Het |
| Hacl1 |
T |
C |
14: 31,362,491 (GRCm39) |
E52G |
probably benign |
Het |
| Ice2 |
A |
G |
9: 69,314,635 (GRCm39) |
Y128C |
probably damaging |
Het |
| Ikzf2 |
T |
A |
1: 69,581,446 (GRCm39) |
I121L |
probably benign |
Het |
| Ipcef1 |
C |
T |
10: 6,869,900 (GRCm39) |
A167T |
probably benign |
Het |
| Jakmip2 |
T |
A |
18: 43,715,145 (GRCm39) |
D127V |
possibly damaging |
Het |
| Jph4 |
T |
C |
14: 55,352,368 (GRCm39) |
T122A |
probably damaging |
Het |
| Kcns2 |
A |
G |
15: 34,838,949 (GRCm39) |
E104G |
probably damaging |
Het |
| Lars2 |
A |
C |
9: 123,260,982 (GRCm39) |
R384S |
probably benign |
Het |
| Lsmem1 |
T |
A |
12: 40,235,407 (GRCm39) |
H3L |
possibly damaging |
Het |
| Lsmem1 |
G |
T |
12: 40,235,408 (GRCm39) |
H3N |
possibly damaging |
Het |
| Ly6g2 |
T |
G |
15: 75,088,605 (GRCm39) |
|
probably null |
Het |
| Mfhas1 |
A |
C |
8: 36,057,222 (GRCm39) |
S566R |
probably benign |
Het |
| Mfhas1 |
C |
G |
8: 36,057,402 (GRCm39) |
R626G |
probably benign |
Het |
| Mgam |
A |
G |
6: 40,643,826 (GRCm39) |
T585A |
probably damaging |
Het |
| Mmp25 |
T |
C |
17: 23,858,997 (GRCm39) |
K185E |
probably benign |
Het |
| Mtch1 |
T |
C |
17: 29,557,750 (GRCm39) |
I243V |
probably damaging |
Het |
| Mtcp1 |
A |
T |
X: 74,455,271 (GRCm39) |
Y25* |
probably null |
Het |
| Mybl2 |
A |
G |
2: 162,901,503 (GRCm39) |
T35A |
probably benign |
Het |
| Myh11 |
T |
C |
16: 14,041,744 (GRCm39) |
E736G |
probably damaging |
Het |
| Myh2 |
T |
C |
11: 67,067,385 (GRCm39) |
I224T |
probably damaging |
Het |
| Mymx |
T |
C |
17: 45,912,759 (GRCm39) |
|
probably benign |
Het |
| Nek10 |
A |
G |
14: 14,863,454 (GRCm38) |
|
probably null |
Het |
| Nsd1 |
A |
T |
13: 55,394,182 (GRCm39) |
K697N |
probably damaging |
Het |
| Nynrin |
A |
G |
14: 56,110,404 (GRCm39) |
D1837G |
possibly damaging |
Het |
| Or14j4 |
G |
A |
17: 37,921,168 (GRCm39) |
T158I |
probably benign |
Het |
| Or2ag2b |
A |
G |
7: 106,418,214 (GRCm39) |
H308R |
probably benign |
Het |
| Or52s1 |
A |
T |
7: 102,861,093 (GRCm39) |
T9S |
probably benign |
Het |
| Or5p81 |
T |
A |
7: 108,266,851 (GRCm39) |
I76N |
probably benign |
Het |
| Or6k4 |
T |
A |
1: 173,964,760 (GRCm39) |
I150N |
probably benign |
Het |
| Pgap6 |
T |
C |
17: 26,341,194 (GRCm39) |
Y766H |
probably damaging |
Het |
| Phf19 |
T |
C |
2: 34,801,781 (GRCm39) |
T10A |
probably benign |
Het |
| Pkd1 |
A |
T |
17: 24,784,558 (GRCm39) |
H368L |
probably benign |
Het |
| Plscr2 |
A |
G |
9: 92,172,808 (GRCm39) |
R156G |
probably damaging |
Het |
| Ppp1r42 |
G |
A |
1: 10,070,311 (GRCm39) |
R61C |
probably benign |
Het |
| Pptc7 |
T |
G |
5: 122,451,679 (GRCm39) |
V45G |
probably damaging |
Het |
| Prlhr |
G |
A |
19: 60,455,867 (GRCm39) |
T233I |
probably damaging |
Het |
| Prr23a4 |
T |
A |
9: 98,785,446 (GRCm39) |
I37N |
possibly damaging |
Het |
| Reps1 |
C |
T |
10: 17,983,462 (GRCm39) |
T435I |
probably damaging |
Het |
| Ret |
T |
A |
6: 118,130,912 (GRCm39) |
T1084S |
probably damaging |
Het |
| Rgl2 |
T |
A |
17: 34,152,595 (GRCm39) |
M402K |
probably benign |
Het |
| Rp2 |
A |
G |
X: 20,243,154 (GRCm39) |
K43R |
probably benign |
Het |
| Rundc3b |
A |
T |
5: 8,629,117 (GRCm39) |
W95R |
probably damaging |
Het |
| Samd9l |
T |
C |
6: 3,375,107 (GRCm39) |
D718G |
possibly damaging |
Het |
| Scnn1b |
G |
A |
7: 121,502,068 (GRCm39) |
R242H |
probably benign |
Het |
| Smad4 |
G |
T |
18: 73,774,965 (GRCm39) |
Q445K |
probably benign |
Het |
| Smchd1 |
G |
T |
17: 71,677,332 (GRCm39) |
P1486T |
probably damaging |
Het |
| Snx25 |
G |
T |
8: 46,488,669 (GRCm39) |
N895K |
possibly damaging |
Het |
| Sox2 |
A |
G |
3: 34,704,890 (GRCm39) |
D109G |
probably damaging |
Het |
| Stfa2 |
A |
T |
16: 36,225,564 (GRCm39) |
N38K |
probably damaging |
Het |
| Stfa2 |
C |
A |
16: 36,225,573 (GRCm39) |
E35D |
possibly damaging |
Het |
| Stfa3 |
A |
G |
16: 36,271,023 (GRCm39) |
L87P |
probably damaging |
Het |
| Strbp |
T |
C |
2: 37,530,921 (GRCm39) |
D111G |
possibly damaging |
Het |
| Supt20 |
C |
A |
3: 54,635,079 (GRCm39) |
|
probably benign |
Het |
| Svep1 |
A |
G |
4: 58,096,310 (GRCm39) |
Y1437H |
possibly damaging |
Het |
| Tbx4 |
T |
A |
11: 85,802,746 (GRCm39) |
|
probably null |
Het |
| Tmem117 |
A |
T |
15: 94,992,432 (GRCm39) |
N364I |
probably damaging |
Het |
| Trat1 |
T |
C |
16: 48,581,742 (GRCm39) |
E45G |
probably damaging |
Het |
| Trpc2 |
G |
A |
7: 101,733,326 (GRCm39) |
D92N |
probably damaging |
Het |
| Trpm1 |
G |
A |
7: 63,876,530 (GRCm39) |
D528N |
probably damaging |
Het |
| Ttll9 |
A |
G |
2: 152,842,156 (GRCm39) |
S337G |
possibly damaging |
Het |
| Utrn |
A |
T |
10: 12,351,018 (GRCm39) |
I355N |
probably damaging |
Het |
| Vangl1 |
A |
G |
3: 102,070,782 (GRCm39) |
S385P |
probably benign |
Het |
| Vmn1r209 |
A |
G |
13: 22,990,409 (GRCm39) |
S94P |
possibly damaging |
Het |
| Vmn2r28 |
T |
A |
7: 5,496,810 (GRCm39) |
Q14L |
probably benign |
Het |
| Vps45 |
A |
G |
3: 95,954,557 (GRCm39) |
|
probably null |
Het |
| Wdr48 |
T |
C |
9: 119,733,396 (GRCm39) |
V81A |
probably benign |
Het |
| Xpnpep2 |
A |
G |
X: 47,214,230 (GRCm39) |
N476S |
probably benign |
Het |
| Zbtb41 |
A |
T |
1: 139,374,660 (GRCm39) |
K707* |
probably null |
Het |
| Zfp442 |
A |
C |
2: 150,250,983 (GRCm39) |
C306W |
probably damaging |
Het |
| Zfp811 |
T |
C |
17: 33,017,116 (GRCm39) |
N307S |
possibly damaging |
Het |
| Zfp976 |
A |
G |
7: 42,265,735 (GRCm39) |
W17R |
probably damaging |
Het |
| Zyg11b |
T |
C |
4: 108,123,290 (GRCm39) |
T226A |
possibly damaging |
Het |
|
| Other mutations in Greb1l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00485:Greb1l
|
APN |
18 |
10,555,962 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01554:Greb1l
|
APN |
18 |
10,522,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01563:Greb1l
|
APN |
18 |
10,469,399 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01944:Greb1l
|
APN |
18 |
10,557,280 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02110:Greb1l
|
APN |
18 |
10,515,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02249:Greb1l
|
APN |
18 |
10,532,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02318:Greb1l
|
APN |
18 |
10,469,388 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02340:Greb1l
|
APN |
18 |
10,515,200 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02516:Greb1l
|
APN |
18 |
10,537,064 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02566:Greb1l
|
APN |
18 |
10,503,299 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02583:Greb1l
|
APN |
18 |
10,542,362 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02838:Greb1l
|
APN |
18 |
10,560,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
A4554:Greb1l
|
UTSW |
18 |
10,532,862 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,032 (GRCm39) |
missense |
probably benign |
0.08 |
|
PIT4453001:Greb1l
|
UTSW |
18 |
10,533,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0099:Greb1l
|
UTSW |
18 |
10,509,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0226:Greb1l
|
UTSW |
18 |
10,522,076 (GRCm39) |
intron |
probably benign |
|
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Greb1l
|
UTSW |
18 |
10,560,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0239:Greb1l
|
UTSW |
18 |
10,458,567 (GRCm39) |
splice site |
probably benign |
|
|
R0316:Greb1l
|
UTSW |
18 |
10,547,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0369:Greb1l
|
UTSW |
18 |
10,469,375 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0394:Greb1l
|
UTSW |
18 |
10,523,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0478:Greb1l
|
UTSW |
18 |
10,509,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0555:Greb1l
|
UTSW |
18 |
10,458,781 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Greb1l
|
UTSW |
18 |
10,474,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1282:Greb1l
|
UTSW |
18 |
10,547,289 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1574:Greb1l
|
UTSW |
18 |
10,554,997 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1607:Greb1l
|
UTSW |
18 |
10,529,703 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1666:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1666:Greb1l
|
UTSW |
18 |
10,501,080 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1720:Greb1l
|
UTSW |
18 |
10,553,848 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1808:Greb1l
|
UTSW |
18 |
10,542,143 (GRCm39) |
missense |
probably benign |
|
|
R1897:Greb1l
|
UTSW |
18 |
10,498,992 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1967:Greb1l
|
UTSW |
18 |
10,501,049 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2025:Greb1l
|
UTSW |
18 |
10,515,221 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2086:Greb1l
|
UTSW |
18 |
10,523,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2125:Greb1l
|
UTSW |
18 |
10,511,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2139:Greb1l
|
UTSW |
18 |
10,555,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2255:Greb1l
|
UTSW |
18 |
10,554,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2256:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2257:Greb1l
|
UTSW |
18 |
10,503,307 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2880:Greb1l
|
UTSW |
18 |
10,547,288 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3623:Greb1l
|
UTSW |
18 |
10,542,380 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3778:Greb1l
|
UTSW |
18 |
10,469,444 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3975:Greb1l
|
UTSW |
18 |
10,522,247 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4038:Greb1l
|
UTSW |
18 |
10,515,209 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4062:Greb1l
|
UTSW |
18 |
10,522,150 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4134:Greb1l
|
UTSW |
18 |
10,529,708 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4342:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4409:Greb1l
|
UTSW |
18 |
10,503,182 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R4600:Greb1l
|
UTSW |
18 |
10,553,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4618:Greb1l
|
UTSW |
18 |
10,498,965 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4683:Greb1l
|
UTSW |
18 |
10,529,563 (GRCm39) |
splice site |
probably null |
|
|
R4686:Greb1l
|
UTSW |
18 |
10,522,112 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4707:Greb1l
|
UTSW |
18 |
10,532,922 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4780:Greb1l
|
UTSW |
18 |
10,541,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4819:Greb1l
|
UTSW |
18 |
10,458,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4925:Greb1l
|
UTSW |
18 |
10,547,447 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R4960:Greb1l
|
UTSW |
18 |
10,547,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5150:Greb1l
|
UTSW |
18 |
10,555,950 (GRCm39) |
frame shift |
probably null |
|
|
R5154:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5269:Greb1l
|
UTSW |
18 |
10,511,409 (GRCm39) |
missense |
probably benign |
|
|
R5290:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5310:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5328:Greb1l
|
UTSW |
18 |
10,553,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5337:Greb1l
|
UTSW |
18 |
10,509,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5393:Greb1l
|
UTSW |
18 |
10,458,312 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5402:Greb1l
|
UTSW |
18 |
10,537,169 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5718:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5719:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5720:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5721:Greb1l
|
UTSW |
18 |
10,542,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5902:Greb1l
|
UTSW |
18 |
10,538,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5993:Greb1l
|
UTSW |
18 |
10,544,455 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6035:Greb1l
|
UTSW |
18 |
10,501,025 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6045:Greb1l
|
UTSW |
18 |
10,547,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Greb1l
|
UTSW |
18 |
10,557,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6297:Greb1l
|
UTSW |
18 |
10,469,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Greb1l
|
UTSW |
18 |
10,501,076 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6552:Greb1l
|
UTSW |
18 |
10,541,814 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6572:Greb1l
|
UTSW |
18 |
10,522,131 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6575:Greb1l
|
UTSW |
18 |
10,547,347 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6922:Greb1l
|
UTSW |
18 |
10,547,482 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6957:Greb1l
|
UTSW |
18 |
10,558,786 (GRCm39) |
missense |
probably benign |
0.23 |
|
R6962:Greb1l
|
UTSW |
18 |
10,547,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7012:Greb1l
|
UTSW |
18 |
10,529,707 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7179:Greb1l
|
UTSW |
18 |
10,544,576 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7251:Greb1l
|
UTSW |
18 |
10,515,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7275:Greb1l
|
UTSW |
18 |
10,544,561 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7301:Greb1l
|
UTSW |
18 |
10,544,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7307:Greb1l
|
UTSW |
18 |
10,538,142 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7455:Greb1l
|
UTSW |
18 |
10,554,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7832:Greb1l
|
UTSW |
18 |
10,542,056 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7934:Greb1l
|
UTSW |
18 |
10,474,371 (GRCm39) |
nonsense |
probably null |
|
|
R8137:Greb1l
|
UTSW |
18 |
10,474,357 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8138:Greb1l
|
UTSW |
18 |
10,533,060 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8208:Greb1l
|
UTSW |
18 |
10,510,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8227:Greb1l
|
UTSW |
18 |
10,515,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8312:Greb1l
|
UTSW |
18 |
10,511,587 (GRCm39) |
intron |
probably benign |
|
|
R8331:Greb1l
|
UTSW |
18 |
10,458,706 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8364:Greb1l
|
UTSW |
18 |
10,529,687 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8389:Greb1l
|
UTSW |
18 |
10,529,613 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8695:Greb1l
|
UTSW |
18 |
10,544,450 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8795:Greb1l
|
UTSW |
18 |
10,553,739 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8836:Greb1l
|
UTSW |
18 |
10,509,257 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8862:Greb1l
|
UTSW |
18 |
10,555,042 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8872:Greb1l
|
UTSW |
18 |
10,529,684 (GRCm39) |
missense |
probably benign |
0.18 |
|
R8874:Greb1l
|
UTSW |
18 |
10,544,896 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8886:Greb1l
|
UTSW |
18 |
10,553,843 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8921:Greb1l
|
UTSW |
18 |
10,541,825 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8997:Greb1l
|
UTSW |
18 |
10,510,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Greb1l
|
UTSW |
18 |
10,541,675 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9018:Greb1l
|
UTSW |
18 |
10,542,004 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9074:Greb1l
|
UTSW |
18 |
10,558,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9074:Greb1l
|
UTSW |
18 |
10,532,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9117:Greb1l
|
UTSW |
18 |
10,542,422 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9189:Greb1l
|
UTSW |
18 |
10,499,983 (GRCm39) |
missense |
probably benign |
|
|
R9332:Greb1l
|
UTSW |
18 |
10,532,796 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9367:Greb1l
|
UTSW |
18 |
10,522,130 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9497:Greb1l
|
UTSW |
18 |
10,458,600 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9796:Greb1l
|
UTSW |
18 |
10,538,233 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
Z1176:Greb1l
|
UTSW |
18 |
10,515,305 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATCATGCTGACTGCTATGC -3'
(R):5'- AGAGCGTAATTACATGGATGCTG -3'
Sequencing Primer
(F):5'- CAGGAGTTTTCTGTGAGAGAGC -3'
(R):5'- CATGGATGCTGGAAATATCAATTGC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation