Incidental Mutation 'R1831:Megf6'
| ID |
207310 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Megf6
|
| Ensembl Gene |
ENSMUSG00000057751 |
| Gene Name |
multiple EGF-like-domains 6 |
| Synonyms |
2600001P17Rik, Egfl3 |
| MMRRC Submission |
039858-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1831 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
154255187-154360170 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 154355134 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Methionine
at position 1483
(T1483M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000030897
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030897]
[ENSMUST00000152159]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030897
AA Change: T1483M
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000030897
Gene: ENSMUSG00000057751
AA Change: T1483M
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
EGF_CA
|
122 |
162 |
1.54e-6 |
SMART |
|
EGF_CA
|
163 |
203 |
2.08e-12 |
SMART |
|
EGF
|
207 |
245 |
5.4e-2 |
SMART |
|
EGF
|
249 |
286 |
2.39e-3 |
SMART |
|
EGF_CA
|
287 |
327 |
4.96e-10 |
SMART |
|
EGF
|
336 |
373 |
1.64e-1 |
SMART |
|
EGF
|
377 |
413 |
1.99e1 |
SMART |
|
EGF_CA
|
414 |
454 |
7.4e-9 |
SMART |
|
EGF
|
521 |
554 |
4.26e0 |
SMART |
|
EGF_Lam
|
570 |
609 |
1.19e-3 |
SMART |
|
EGF_like
|
613 |
652 |
5.29e-1 |
SMART |
|
EGF
|
642 |
685 |
2.2e1 |
SMART |
|
EGF_Lam
|
656 |
697 |
1.04e-3 |
SMART |
|
EGF
|
687 |
730 |
1.59e1 |
SMART |
|
EGF_like
|
701 |
742 |
2.27e0 |
SMART |
|
EGF_Lam
|
746 |
784 |
1.33e-1 |
SMART |
|
EGF
|
783 |
816 |
2.85e-1 |
SMART |
|
EGF_Lam
|
832 |
871 |
3.88e-3 |
SMART |
|
EGF_Lam
|
875 |
915 |
3.25e-5 |
SMART |
|
EGF
|
914 |
946 |
4.7e-2 |
SMART |
|
EGF_like
|
962 |
1001 |
1.69e-1 |
SMART |
|
EGF
|
1000 |
1032 |
7.02e-1 |
SMART |
|
EGF_Lam
|
1048 |
1087 |
3.1e-2 |
SMART |
|
EGF
|
1077 |
1118 |
7.53e-1 |
SMART |
|
EGF_like
|
1091 |
1130 |
5.59e-1 |
SMART |
|
EGF
|
1129 |
1161 |
5.04e-2 |
SMART |
|
EGF_Lam
|
1177 |
1216 |
2.94e-3 |
SMART |
|
EGF
|
1206 |
1248 |
1.87e1 |
SMART |
|
EGF_Lam
|
1220 |
1260 |
3.1e-2 |
SMART |
|
EGF
|
1259 |
1291 |
1.73e0 |
SMART |
|
EGF
|
1302 |
1334 |
6.55e-1 |
SMART |
|
EGF
|
1345 |
1377 |
4.39e-2 |
SMART |
|
EGF_Lam
|
1393 |
1432 |
7.64e-2 |
SMART |
|
EGF_Lam
|
1436 |
1475 |
2.64e-5 |
SMART |
|
EGF_like
|
1465 |
1506 |
4.2e1 |
SMART |
|
EGF_Lam
|
1479 |
1518 |
1.19e-3 |
SMART |
|
EGF
|
1517 |
1549 |
1.84e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127088
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128700
|
| SMART Domains |
Protein: ENSMUSP00000117277
Gene: ENSMUSG00000057751
| Domain | Start | End | E-Value | Type |
|---|
|
EGF_Lam
|
3 |
42 |
3.1e-2 |
SMART |
|
EGF
|
32 |
73 |
7.53e-1 |
SMART |
|
EGF_like
|
46 |
85 |
8.92e-1 |
SMART |
|
EGF
|
84 |
116 |
7.13e-2 |
SMART |
|
EGF
|
127 |
159 |
1.73e0 |
SMART |
|
EGF
|
170 |
202 |
6.55e-1 |
SMART |
|
EGF
|
213 |
245 |
4.39e-2 |
SMART |
|
EGF_Lam
|
261 |
300 |
7.64e-2 |
SMART |
|
EGF
|
299 |
331 |
1.51e0 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000138945
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142110
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152159
|
| SMART Domains |
Protein: ENSMUSP00000121641
Gene: ENSMUSG00000057751
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
EGF_CA
|
55 |
95 |
2.08e-12 |
SMART |
|
EGF
|
99 |
137 |
5.4e-2 |
SMART |
|
EGF
|
141 |
178 |
2.39e-3 |
SMART |
|
EGF_CA
|
179 |
219 |
4.96e-10 |
SMART |
|
EGF
|
228 |
265 |
1.64e-1 |
SMART |
|
EGF
|
269 |
305 |
1.99e1 |
SMART |
|
EGF_CA
|
306 |
346 |
7.4e-9 |
SMART |
|
EGF
|
413 |
446 |
4.26e0 |
SMART |
|
EGF_Lam
|
462 |
501 |
1.19e-3 |
SMART |
|
EGF_like
|
505 |
544 |
5.29e-1 |
SMART |
|
EGF
|
534 |
577 |
2.2e1 |
SMART |
|
EGF_Lam
|
548 |
589 |
1.04e-3 |
SMART |
|
EGF
|
579 |
622 |
1.59e1 |
SMART |
|
EGF_like
|
593 |
634 |
2.27e0 |
SMART |
|
EGF_Lam
|
638 |
676 |
1.33e-1 |
SMART |
|
EGF
|
675 |
708 |
2.85e-1 |
SMART |
|
EGF_Lam
|
724 |
763 |
3.88e-3 |
SMART |
|
EGF_Lam
|
767 |
807 |
3.25e-5 |
SMART |
|
EGF
|
806 |
838 |
4.7e-2 |
SMART |
|
EGF_Lam
|
854 |
893 |
2.56e-3 |
SMART |
|
EGF
|
892 |
924 |
2.02e-1 |
SMART |
|
EGF
|
935 |
967 |
7.13e-2 |
SMART |
|
EGF
|
978 |
1010 |
1.73e0 |
SMART |
|
EGF
|
1021 |
1053 |
6.55e-1 |
SMART |
|
EGF
|
1064 |
1096 |
4.39e-2 |
SMART |
|
EGF
|
1107 |
1139 |
4.97e-1 |
SMART |
|
EGF
|
1159 |
1191 |
1.84e1 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700109H08Rik |
A |
G |
5: 3,627,255 (GRCm39) |
D77G |
probably damaging |
Het |
| Adam1b |
A |
G |
5: 121,641,000 (GRCm39) |
I15T |
possibly damaging |
Het |
| Arfgef1 |
G |
C |
1: 10,275,115 (GRCm39) |
I312M |
probably benign |
Het |
| Capn8 |
G |
A |
1: 182,438,666 (GRCm39) |
|
probably null |
Het |
| Carmil1 |
A |
T |
13: 24,348,862 (GRCm39) |
V15E |
probably benign |
Het |
| Ccdc42 |
T |
A |
11: 68,481,805 (GRCm39) |
M133K |
probably benign |
Het |
| Cd5 |
T |
C |
19: 10,696,933 (GRCm39) |
D485G |
probably damaging |
Het |
| Cdhr18 |
A |
G |
14: 13,899,619 (GRCm38) |
I101T |
probably damaging |
Het |
| Cep104 |
T |
A |
4: 154,087,003 (GRCm39) |
V842E |
probably benign |
Het |
| Cep162 |
T |
A |
9: 87,088,985 (GRCm39) |
I966L |
probably damaging |
Het |
| Cklf |
T |
C |
8: 104,977,687 (GRCm39) |
F13S |
probably damaging |
Het |
| Csf2rb |
C |
T |
15: 78,232,453 (GRCm39) |
P587S |
probably benign |
Het |
| Cyp21a1 |
A |
T |
17: 35,023,009 (GRCm39) |
|
probably benign |
Het |
| Cyp26a1 |
A |
T |
19: 37,689,071 (GRCm39) |
L335F |
probably damaging |
Het |
| Dcst1 |
A |
G |
3: 89,260,057 (GRCm39) |
F596L |
probably damaging |
Het |
| Dennd6a |
T |
A |
14: 26,328,109 (GRCm39) |
L44H |
probably damaging |
Het |
| Dnah6 |
G |
A |
6: 73,158,780 (GRCm39) |
R608C |
possibly damaging |
Het |
| Dnajb5 |
A |
T |
4: 42,957,333 (GRCm39) |
T311S |
probably benign |
Het |
| Dthd1 |
A |
G |
5: 62,984,572 (GRCm39) |
T426A |
probably benign |
Het |
| Dync1h1 |
A |
G |
12: 110,580,493 (GRCm39) |
K118R |
probably damaging |
Het |
| Efemp1 |
A |
T |
11: 28,871,442 (GRCm39) |
D347V |
possibly damaging |
Het |
| Ephb4 |
T |
A |
5: 137,352,677 (GRCm39) |
Y87N |
probably damaging |
Het |
| Ern1 |
A |
T |
11: 106,290,668 (GRCm39) |
|
probably null |
Het |
| Fam184a |
A |
T |
10: 53,523,180 (GRCm39) |
D164E |
probably damaging |
Het |
| Fkbp10 |
A |
G |
11: 100,314,045 (GRCm39) |
E351G |
probably damaging |
Het |
| Fmn2 |
A |
G |
1: 174,437,511 (GRCm39) |
S1161G |
probably benign |
Het |
| Frem1 |
A |
G |
4: 82,939,074 (GRCm39) |
S3P |
possibly damaging |
Het |
| Gpr3 |
C |
T |
4: 132,938,454 (GRCm39) |
A73T |
possibly damaging |
Het |
| Gprc6a |
T |
C |
10: 51,491,902 (GRCm39) |
T616A |
probably benign |
Het |
| Gtf3c2 |
G |
T |
5: 31,325,713 (GRCm39) |
Q452K |
probably damaging |
Het |
| H2-Q7 |
C |
A |
17: 35,658,675 (GRCm39) |
S104R |
probably benign |
Het |
| Hacd2 |
T |
C |
16: 34,922,434 (GRCm39) |
Y208H |
probably damaging |
Het |
| Hid1 |
C |
T |
11: 115,239,729 (GRCm39) |
G734R |
probably damaging |
Het |
| Ifi207 |
A |
G |
1: 173,559,992 (GRCm39) |
I160T |
unknown |
Het |
| Itga11 |
T |
A |
9: 62,689,300 (GRCm39) |
L1155Q |
probably damaging |
Het |
| Kmt2d |
A |
G |
15: 98,753,224 (GRCm39) |
S157P |
probably damaging |
Het |
| Lamb3 |
A |
G |
1: 193,017,187 (GRCm39) |
T793A |
probably damaging |
Het |
| Lonrf2 |
G |
A |
1: 38,852,357 (GRCm39) |
P165S |
probably benign |
Het |
| Lrrc66 |
G |
A |
5: 73,764,769 (GRCm39) |
S758L |
possibly damaging |
Het |
| Ltn1 |
C |
T |
16: 87,197,034 (GRCm39) |
S1213N |
possibly damaging |
Het |
| Meak7 |
T |
C |
8: 120,497,992 (GRCm39) |
M171V |
probably null |
Het |
| Med1 |
T |
C |
11: 98,047,437 (GRCm39) |
|
probably benign |
Het |
| Micall2 |
A |
G |
5: 139,702,508 (GRCm39) |
V245A |
probably benign |
Het |
| Mipep |
T |
G |
14: 61,109,512 (GRCm39) |
Y630D |
probably damaging |
Het |
| Ndst3 |
T |
A |
3: 123,395,127 (GRCm39) |
H501L |
probably benign |
Het |
| Nek10 |
A |
T |
14: 14,842,789 (GRCm38) |
M165L |
probably benign |
Het |
| Nmbr |
C |
A |
10: 14,642,609 (GRCm39) |
T56K |
probably benign |
Het |
| Nxpe2 |
T |
A |
9: 48,237,452 (GRCm39) |
M268L |
probably benign |
Het |
| Oasl2 |
A |
G |
5: 115,039,367 (GRCm39) |
Y185C |
probably benign |
Het |
| Ogdhl |
T |
A |
14: 32,059,484 (GRCm39) |
V377E |
probably damaging |
Het |
| Or11g1 |
T |
A |
14: 50,651,658 (GRCm39) |
|
probably null |
Het |
| Or14j4 |
G |
A |
17: 37,920,730 (GRCm39) |
S304L |
possibly damaging |
Het |
| Ovgp1 |
A |
G |
3: 105,892,384 (GRCm39) |
R346G |
probably benign |
Het |
| Parp14 |
T |
A |
16: 35,678,958 (GRCm39) |
N337Y |
possibly damaging |
Het |
| Pask |
A |
C |
1: 93,248,491 (GRCm39) |
|
probably null |
Het |
| Pax3 |
G |
T |
1: 78,108,977 (GRCm39) |
T227K |
probably damaging |
Het |
| Pik3r6 |
T |
A |
11: 68,434,860 (GRCm39) |
M594K |
probably benign |
Het |
| Pms1 |
A |
G |
1: 53,246,370 (GRCm39) |
F390L |
probably benign |
Het |
| Polg |
G |
A |
7: 79,109,518 (GRCm39) |
T433I |
probably benign |
Het |
| Prex1 |
T |
C |
2: 166,427,021 (GRCm39) |
Y898C |
probably damaging |
Het |
| Ranbp2 |
T |
A |
10: 58,315,044 (GRCm39) |
C1921* |
probably null |
Het |
| Rif1 |
T |
A |
2: 51,968,507 (GRCm39) |
L230* |
probably null |
Het |
| Rnf148 |
A |
G |
6: 23,654,772 (GRCm39) |
F75L |
probably damaging |
Het |
| Rps18-ps6 |
A |
G |
13: 97,897,053 (GRCm39) |
V15A |
probably benign |
Het |
| Sclt1 |
A |
G |
3: 41,681,546 (GRCm39) |
V91A |
probably damaging |
Het |
| Sirt1 |
T |
C |
10: 63,156,425 (GRCm39) |
D735G |
probably benign |
Het |
| Spag5 |
T |
A |
11: 78,205,082 (GRCm39) |
N622K |
probably benign |
Het |
| Sspo |
T |
G |
6: 48,466,720 (GRCm39) |
C3935W |
probably damaging |
Het |
| Strbp |
A |
G |
2: 37,515,277 (GRCm39) |
S250P |
possibly damaging |
Het |
| Tgfbr2 |
T |
C |
9: 115,919,604 (GRCm39) |
T541A |
possibly damaging |
Het |
| Thada |
A |
C |
17: 84,538,542 (GRCm39) |
S1489A |
probably damaging |
Het |
| Tiam1 |
A |
T |
16: 89,657,182 (GRCm39) |
S685T |
probably benign |
Het |
| Tpsb2 |
T |
A |
17: 25,585,494 (GRCm39) |
|
probably null |
Het |
| Trip4 |
C |
A |
9: 65,765,622 (GRCm39) |
G359V |
probably damaging |
Het |
| Tsr1 |
T |
C |
11: 74,791,182 (GRCm39) |
F254L |
probably benign |
Het |
| Vmn1r120 |
T |
C |
7: 20,787,556 (GRCm39) |
K52E |
probably benign |
Het |
| Vmn1r29 |
C |
A |
6: 58,284,692 (GRCm39) |
Y137* |
probably null |
Het |
| Vmn2r52 |
T |
C |
7: 9,893,415 (GRCm39) |
K575E |
probably damaging |
Het |
| Wdr95 |
A |
G |
5: 149,475,891 (GRCm39) |
Y63C |
probably damaging |
Het |
|
| Other mutations in Megf6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01122:Megf6
|
APN |
4 |
154,338,264 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Megf6
|
APN |
4 |
154,337,020 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01512:Megf6
|
APN |
4 |
154,347,040 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01824:Megf6
|
APN |
4 |
154,336,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02172:Megf6
|
APN |
4 |
154,355,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02727:Megf6
|
APN |
4 |
154,337,606 (GRCm39) |
splice site |
probably null |
|
|
IGL02966:Megf6
|
APN |
4 |
154,338,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Didactic
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0118:Megf6
|
UTSW |
4 |
154,339,098 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0220:Megf6
|
UTSW |
4 |
154,342,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Megf6
|
UTSW |
4 |
154,339,092 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0383:Megf6
|
UTSW |
4 |
154,349,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0417:Megf6
|
UTSW |
4 |
154,352,424 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0526:Megf6
|
UTSW |
4 |
154,343,398 (GRCm39) |
missense |
probably benign |
|
|
R0528:Megf6
|
UTSW |
4 |
154,343,630 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0928:Megf6
|
UTSW |
4 |
154,261,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1311:Megf6
|
UTSW |
4 |
154,348,239 (GRCm39) |
splice site |
probably null |
|
|
R1458:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1470:Megf6
|
UTSW |
4 |
154,336,876 (GRCm39) |
splice site |
probably benign |
|
|
R1476:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1479:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1624:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1626:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1638:Megf6
|
UTSW |
4 |
154,346,967 (GRCm39) |
splice site |
probably benign |
|
|
R1777:Megf6
|
UTSW |
4 |
154,355,147 (GRCm39) |
nonsense |
probably null |
|
|
R1944:Megf6
|
UTSW |
4 |
154,340,523 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1984:Megf6
|
UTSW |
4 |
154,352,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Megf6
|
UTSW |
4 |
154,261,578 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2448:Megf6
|
UTSW |
4 |
154,351,102 (GRCm39) |
splice site |
probably null |
|
|
R2880:Megf6
|
UTSW |
4 |
154,337,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4032:Megf6
|
UTSW |
4 |
154,261,550 (GRCm39) |
nonsense |
probably null |
|
|
R4058:Megf6
|
UTSW |
4 |
154,326,989 (GRCm39) |
splice site |
probably benign |
|
|
R4672:Megf6
|
UTSW |
4 |
154,333,909 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4688:Megf6
|
UTSW |
4 |
154,338,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4752:Megf6
|
UTSW |
4 |
154,336,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:Megf6
|
UTSW |
4 |
154,338,738 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4909:Megf6
|
UTSW |
4 |
154,349,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4942:Megf6
|
UTSW |
4 |
154,338,277 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4981:Megf6
|
UTSW |
4 |
154,351,907 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4990:Megf6
|
UTSW |
4 |
154,351,683 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5001:Megf6
|
UTSW |
4 |
154,352,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5189:Megf6
|
UTSW |
4 |
154,336,980 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5210:Megf6
|
UTSW |
4 |
154,354,273 (GRCm39) |
intron |
probably benign |
|
|
R5220:Megf6
|
UTSW |
4 |
154,338,295 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5250:Megf6
|
UTSW |
4 |
154,340,467 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5697:Megf6
|
UTSW |
4 |
154,342,686 (GRCm39) |
missense |
probably null |
0.15 |
|
R5808:Megf6
|
UTSW |
4 |
154,352,119 (GRCm39) |
missense |
probably benign |
|
|
R5916:Megf6
|
UTSW |
4 |
154,333,882 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6054:Megf6
|
UTSW |
4 |
154,347,636 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6075:Megf6
|
UTSW |
4 |
154,347,056 (GRCm39) |
nonsense |
probably null |
|
|
R6515:Megf6
|
UTSW |
4 |
154,343,376 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6599:Megf6
|
UTSW |
4 |
154,342,544 (GRCm39) |
splice site |
probably null |
|
|
R6811:Megf6
|
UTSW |
4 |
154,336,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6925:Megf6
|
UTSW |
4 |
154,339,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7023:Megf6
|
UTSW |
4 |
154,338,602 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7117:Megf6
|
UTSW |
4 |
154,343,379 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7163:Megf6
|
UTSW |
4 |
154,351,898 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7345:Megf6
|
UTSW |
4 |
154,351,772 (GRCm39) |
missense |
probably benign |
|
|
R7580:Megf6
|
UTSW |
4 |
154,355,201 (GRCm39) |
nonsense |
probably null |
|
|
R7649:Megf6
|
UTSW |
4 |
154,349,542 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7702:Megf6
|
UTSW |
4 |
154,354,927 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8010:Megf6
|
UTSW |
4 |
154,354,964 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8175:Megf6
|
UTSW |
4 |
154,353,076 (GRCm39) |
nonsense |
probably null |
|
|
R8231:Megf6
|
UTSW |
4 |
154,336,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8436:Megf6
|
UTSW |
4 |
154,349,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8460:Megf6
|
UTSW |
4 |
154,350,634 (GRCm39) |
nonsense |
probably null |
|
|
R8738:Megf6
|
UTSW |
4 |
154,352,436 (GRCm39) |
missense |
probably benign |
|
|
R8854:Megf6
|
UTSW |
4 |
154,352,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Megf6
|
UTSW |
4 |
154,326,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9098:Megf6
|
UTSW |
4 |
154,354,160 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9147:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9148:Megf6
|
UTSW |
4 |
154,339,130 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9161:Megf6
|
UTSW |
4 |
154,352,172 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9355:Megf6
|
UTSW |
4 |
154,338,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9386:Megf6
|
UTSW |
4 |
154,340,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9404:Megf6
|
UTSW |
4 |
154,348,225 (GRCm39) |
missense |
|
|
|
R9469:Megf6
|
UTSW |
4 |
154,335,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9472:Megf6
|
UTSW |
4 |
154,333,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9777:Megf6
|
UTSW |
4 |
154,343,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Megf6
|
UTSW |
4 |
154,322,283 (GRCm39) |
missense |
probably benign |
0.12 |
|
Z1177:Megf6
|
UTSW |
4 |
154,354,198 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,204 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Megf6
|
UTSW |
4 |
154,352,139 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Megf6
|
UTSW |
4 |
154,352,138 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
Z1177:Megf6
|
UTSW |
4 |
154,335,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTGCGAGTGTCAACAGGGC -3'
(R):5'- AGCTCCGATGGATGTCTATGC -3'
Sequencing Primer
(F):5'- TGTGACCCTGTCAGTGGC -3'
(R):5'- GCACAGTGCCTAGTCTGAG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation