Incidental Mutation 'R1843:Zfp462'
| ID |
207403 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp462
|
| Ensembl Gene |
ENSMUSG00000060206 |
| Gene Name |
zinc finger protein 462 |
| Synonyms |
Zfpip, 9430078C22Rik, Gt4-2 |
| MMRRC Submission |
039868-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.831)
|
| Stock # |
R1843 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
54945048-55083563 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 55010010 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Alanine
at position 659
(S659A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000095677
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030131]
[ENSMUST00000079605]
[ENSMUST00000098070]
[ENSMUST00000133895]
|
| AlphaFold |
B1AWL2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000030131
|
| SMART Domains |
Protein: ENSMUSP00000030131
Gene: ENSMUSG00000060206
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
35 |
58 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
106 |
129 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
153 |
176 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
210 |
233 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
311 |
334 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
356 |
379 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
418 |
441 |
5.34e-1 |
SMART |
|
low complexity region
|
450 |
463 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
524 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
538 |
561 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
608 |
631 |
6.4e0 |
SMART |
|
low complexity region
|
655 |
676 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
687 |
711 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
733 |
755 |
1.08e-1 |
SMART |
|
low complexity region
|
757 |
771 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
809 |
831 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
892 |
914 |
3.11e-2 |
SMART |
|
ZnF_C2H2
|
926 |
948 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
955 |
978 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
984 |
1007 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
1092 |
1115 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
1121 |
1144 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
1155 |
1177 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
1201 |
1223 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
1229 |
1252 |
2.02e-1 |
SMART |
|
low complexity region
|
1273 |
1296 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1315 |
1337 |
2.2e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000079605
|
| SMART Domains |
Protein: ENSMUSP00000078555
Gene: ENSMUSG00000060206
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
35 |
58 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
106 |
129 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
153 |
176 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
210 |
233 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
311 |
334 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
356 |
379 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
418 |
441 |
5.34e-1 |
SMART |
|
low complexity region
|
450 |
463 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
501 |
524 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
538 |
561 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
608 |
631 |
6.4e0 |
SMART |
|
low complexity region
|
655 |
676 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
687 |
711 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
733 |
755 |
1.08e-1 |
SMART |
|
low complexity region
|
757 |
771 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
809 |
831 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
893 |
915 |
3.11e-2 |
SMART |
|
ZnF_C2H2
|
927 |
949 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
956 |
979 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
985 |
1008 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
1093 |
1116 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
1122 |
1145 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
1156 |
1178 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
1202 |
1224 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
1230 |
1253 |
2.02e-1 |
SMART |
|
low complexity region
|
1274 |
1297 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1316 |
1338 |
2.2e-2 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000098070
AA Change: S659A
PolyPhen 2
Score 0.875 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000095677
Gene: ENSMUSG00000060206
AA Change: S659A
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
27 |
5.81e-2 |
SMART |
|
low complexity region
|
81 |
94 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
108 |
131 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
162 |
185 |
4.65e-1 |
SMART |
|
low complexity region
|
194 |
215 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
243 |
266 |
4.98e-1 |
SMART |
|
low complexity region
|
332 |
343 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
440 |
463 |
1.01e-1 |
SMART |
|
ZnF_C2H2
|
471 |
493 |
2.86e-1 |
SMART |
|
low complexity region
|
503 |
515 |
N/A |
INTRINSIC |
|
low complexity region
|
536 |
592 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
593 |
616 |
2.53e-2 |
SMART |
|
low complexity region
|
707 |
736 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
835 |
858 |
5.62e0 |
SMART |
|
ZnF_C2H2
|
878 |
900 |
2.14e0 |
SMART |
|
ZnF_C2H2
|
917 |
940 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
1023 |
1046 |
5.72e-1 |
SMART |
|
low complexity region
|
1092 |
1100 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1107 |
1130 |
4.23e0 |
SMART |
|
ZnF_C2H2
|
1183 |
1206 |
4.81e0 |
SMART |
|
ZnF_C2H2
|
1254 |
1277 |
6.67e-2 |
SMART |
|
ZnF_C2H2
|
1301 |
1324 |
3.47e0 |
SMART |
|
ZnF_C2H2
|
1358 |
1381 |
7.29e0 |
SMART |
|
ZnF_C2H2
|
1459 |
1482 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
1504 |
1527 |
6.57e0 |
SMART |
|
ZnF_C2H2
|
1566 |
1589 |
5.34e-1 |
SMART |
|
low complexity region
|
1598 |
1611 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1649 |
1672 |
8.22e-2 |
SMART |
|
ZnF_C2H2
|
1686 |
1709 |
5.34e0 |
SMART |
|
ZnF_C2H2
|
1756 |
1779 |
6.4e0 |
SMART |
|
low complexity region
|
1803 |
1824 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1835 |
1859 |
3.05e1 |
SMART |
|
ZnF_C2H2
|
1881 |
1903 |
1.08e-1 |
SMART |
|
low complexity region
|
1905 |
1919 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1957 |
1979 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
2014 |
2036 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
2043 |
2066 |
4.98e-1 |
SMART |
|
ZnF_C2H2
|
2072 |
2095 |
5.5e-3 |
SMART |
|
ZnF_C2H2
|
2180 |
2203 |
7.05e-1 |
SMART |
|
ZnF_C2H2
|
2209 |
2232 |
5.48e0 |
SMART |
|
ZnF_C2H2
|
2243 |
2265 |
6.13e-1 |
SMART |
|
ZnF_C2H2
|
2289 |
2311 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
2317 |
2340 |
2.02e-1 |
SMART |
|
low complexity region
|
2361 |
2384 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
2403 |
2425 |
2.2e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000133895
|
| SMART Domains |
Protein: ENSMUSP00000122775
Gene: ENSMUSG00000060206
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
27 |
5.81e-2 |
SMART |
|
low complexity region
|
81 |
93 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
C |
T |
8: 105,708,974 (GRCm38) |
T88M |
probably damaging |
Het |
| 9130011E15Rik |
A |
C |
19: 45,975,252 (GRCm38) |
S42R |
probably benign |
Het |
| 9430038I01Rik |
A |
G |
7: 137,377,066 (GRCm38) |
|
probably benign |
Het |
| Adgra3 |
A |
C |
5: 49,961,492 (GRCm38) |
S905A |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,544,533 (GRCm38) |
Y1618H |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,673,314 (GRCm38) |
T26A |
probably benign |
Het |
| Ankrd13d |
T |
C |
19: 4,271,595 (GRCm38) |
K360E |
probably damaging |
Het |
| Anks1b |
T |
A |
10: 90,512,889 (GRCm38) |
|
probably null |
Het |
| Apob |
T |
C |
12: 8,007,602 (GRCm38) |
F2028S |
possibly damaging |
Het |
| Arap3 |
G |
A |
18: 37,975,583 (GRCm38) |
R1265W |
probably damaging |
Het |
| Arhgef37 |
A |
G |
18: 61,518,050 (GRCm38) |
Y135H |
probably damaging |
Het |
| Atp1a1 |
T |
C |
3: 101,582,017 (GRCm38) |
T760A |
probably benign |
Het |
| Cdc42bpb |
T |
A |
12: 111,322,821 (GRCm38) |
M497L |
probably benign |
Het |
| Ces5a |
C |
T |
8: 93,514,231 (GRCm38) |
V413M |
probably damaging |
Het |
| Chd5 |
A |
T |
4: 152,385,806 (GRCm38) |
Y1903F |
probably damaging |
Het |
| Chd9 |
T |
A |
8: 91,010,794 (GRCm38) |
N1500K |
probably benign |
Het |
| Chmp7 |
G |
T |
14: 69,719,799 (GRCm38) |
D303E |
probably benign |
Het |
| Chrnb4 |
A |
T |
9: 55,034,818 (GRCm38) |
Y391N |
possibly damaging |
Het |
| Crtc1 |
T |
C |
8: 70,388,152 (GRCm38) |
T475A |
probably benign |
Het |
| Cyp2c69 |
A |
G |
19: 39,877,528 (GRCm38) |
I207T |
probably benign |
Het |
| Dcp1a |
A |
G |
14: 30,518,983 (GRCm38) |
E250G |
probably damaging |
Het |
| Ddx20 |
T |
C |
3: 105,679,082 (GRCm38) |
Q649R |
probably benign |
Het |
| Defb12 |
T |
A |
8: 19,112,738 (GRCm38) |
K59N |
probably damaging |
Het |
| Dpy19l3 |
A |
T |
7: 35,729,760 (GRCm38) |
I85N |
probably damaging |
Het |
| Duox2 |
C |
T |
2: 122,292,258 (GRCm38) |
|
probably null |
Het |
| E430018J23Rik |
A |
C |
7: 127,391,488 (GRCm38) |
D442E |
probably benign |
Het |
| Ebi3 |
T |
A |
17: 55,956,679 (GRCm38) |
Y197N |
probably damaging |
Het |
| Emc1 |
G |
A |
4: 139,375,512 (GRCm38) |
R994Q |
probably benign |
Het |
| Ercc6 |
G |
T |
14: 32,546,820 (GRCm38) |
M530I |
probably damaging |
Het |
| Evl |
T |
A |
12: 108,652,996 (GRCm38) |
D70E |
probably damaging |
Het |
| Fam35a |
A |
G |
14: 34,267,803 (GRCm38) |
I382T |
probably benign |
Het |
| Fbln2 |
A |
G |
6: 91,265,775 (GRCm38) |
N819S |
probably damaging |
Het |
| Foxk2 |
A |
G |
11: 121,285,537 (GRCm38) |
I170V |
probably benign |
Het |
| Gfm1 |
T |
C |
3: 67,435,610 (GRCm38) |
V159A |
probably damaging |
Het |
| Gm10837 |
A |
G |
14: 122,490,765 (GRCm38) |
T18A |
unknown |
Het |
| Gm12887 |
A |
T |
4: 121,622,030 (GRCm38) |
V25E |
probably damaging |
Het |
| Hectd4 |
A |
G |
5: 121,297,180 (GRCm38) |
H985R |
possibly damaging |
Het |
| Hsfy2 |
A |
G |
1: 56,636,632 (GRCm38) |
Y249H |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,545,567 (GRCm38) |
V2639A |
probably damaging |
Het |
| Igf2r |
A |
G |
17: 12,704,270 (GRCm38) |
|
probably null |
Het |
| Invs |
T |
A |
4: 48,422,035 (GRCm38) |
I889N |
probably damaging |
Het |
| Kcnq1 |
A |
T |
7: 143,183,120 (GRCm38) |
M209L |
probably benign |
Het |
| Klra7 |
A |
G |
6: 130,229,994 (GRCm38) |
I48T |
possibly damaging |
Het |
| Krt26 |
CTAGTA |
CTA |
11: 99,333,526 (GRCm38) |
|
probably benign |
Het |
| Lrif1 |
T |
A |
3: 106,732,811 (GRCm38) |
V404D |
probably damaging |
Het |
| Lrriq1 |
T |
A |
10: 103,227,173 (GRCm38) |
|
probably null |
Het |
| Lypd6 |
T |
A |
2: 50,188,762 (GRCm38) |
I90N |
possibly damaging |
Het |
| Mbp |
A |
G |
18: 82,584,122 (GRCm38) |
D174G |
probably damaging |
Het |
| Megf9 |
G |
T |
4: 70,534,785 (GRCm38) |
P13Q |
probably damaging |
Het |
| Myo15b |
A |
T |
11: 115,869,586 (GRCm38) |
T1155S |
probably benign |
Het |
| Nlrp6 |
T |
A |
7: 140,923,093 (GRCm38) |
C371S |
probably damaging |
Het |
| Nosip |
T |
A |
7: 45,077,309 (GRCm38) |
|
probably null |
Het |
| Nox3 |
G |
T |
17: 3,669,878 (GRCm38) |
P344H |
probably damaging |
Het |
| Nup210l |
T |
C |
3: 90,172,086 (GRCm38) |
V959A |
probably damaging |
Het |
| Olfr1360 |
C |
A |
13: 21,674,672 (GRCm38) |
V91L |
probably benign |
Het |
| Olfr1475 |
A |
G |
19: 13,479,931 (GRCm38) |
I89T |
probably benign |
Het |
| Olfr175-ps1 |
T |
A |
16: 58,824,077 (GRCm38) |
I211F |
probably damaging |
Het |
| Olfr267 |
T |
C |
4: 58,785,384 (GRCm38) |
I113V |
probably benign |
Het |
| Olfr959 |
A |
G |
9: 39,572,735 (GRCm38) |
Y175H |
possibly damaging |
Het |
| Osbpl3 |
A |
C |
6: 50,370,143 (GRCm38) |
S25A |
probably damaging |
Het |
| Otog |
G |
A |
7: 46,246,283 (GRCm38) |
C107Y |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,784,491 (GRCm38) |
R260C |
probably damaging |
Het |
| Pbrm1 |
A |
T |
14: 31,038,957 (GRCm38) |
I224F |
probably damaging |
Het |
| Pcdh1 |
T |
A |
18: 38,192,225 (GRCm38) |
|
probably null |
Het |
| Pcnx |
T |
C |
12: 81,980,935 (GRCm38) |
L1585P |
probably damaging |
Het |
| Pde4c |
C |
T |
8: 70,747,950 (GRCm38) |
H362Y |
probably damaging |
Het |
| Pdlim2 |
C |
T |
14: 70,164,779 (GRCm38) |
R296H |
probably damaging |
Het |
| Pgm2 |
A |
T |
4: 99,961,478 (GRCm38) |
Q90L |
probably damaging |
Het |
| Phlpp1 |
A |
G |
1: 106,343,505 (GRCm38) |
H814R |
probably benign |
Het |
| Pknox2 |
A |
T |
9: 36,954,831 (GRCm38) |
M5K |
possibly damaging |
Het |
| Pole |
G |
A |
5: 110,330,835 (GRCm38) |
|
probably null |
Het |
| Polr1b |
A |
G |
2: 129,102,966 (GRCm38) |
I61V |
probably benign |
Het |
| Prelp |
T |
C |
1: 133,914,757 (GRCm38) |
K217E |
probably damaging |
Het |
| Prkce |
C |
T |
17: 86,475,546 (GRCm38) |
Q202* |
probably null |
Het |
| Psmd2 |
T |
G |
16: 20,656,582 (GRCm38) |
M370R |
probably benign |
Het |
| Rimklb |
A |
T |
6: 122,464,009 (GRCm38) |
H68Q |
probably damaging |
Het |
| Rnasel |
A |
G |
1: 153,754,674 (GRCm38) |
D312G |
possibly damaging |
Het |
| Rxrg |
A |
T |
1: 167,598,752 (GRCm38) |
M1L |
probably benign |
Het |
| Scrn1 |
A |
G |
6: 54,522,841 (GRCm38) |
F220L |
possibly damaging |
Het |
| Scyl3 |
A |
G |
1: 163,950,675 (GRCm38) |
S461G |
probably benign |
Het |
| Serpina1c |
T |
A |
12: 103,895,023 (GRCm38) |
T411S |
probably benign |
Het |
| Serpinb6d |
C |
T |
13: 33,671,381 (GRCm38) |
P346L |
probably benign |
Het |
| Slc9a3r2 |
C |
T |
17: 24,641,719 (GRCm38) |
S150N |
possibly damaging |
Het |
| Spg21 |
G |
T |
9: 65,465,336 (GRCm38) |
V17F |
probably damaging |
Het |
| Spink5 |
A |
T |
18: 43,999,891 (GRCm38) |
M525L |
probably benign |
Het |
| Sun2 |
T |
C |
15: 79,737,563 (GRCm38) |
T155A |
probably benign |
Het |
| Tchh |
T |
A |
3: 93,446,780 (GRCm38) |
F1176I |
unknown |
Het |
| Tex15 |
T |
A |
8: 33,576,654 (GRCm38) |
D2037E |
probably benign |
Het |
| Tfdp2 |
T |
C |
9: 96,317,804 (GRCm38) |
C392R |
possibly damaging |
Het |
| Tmem30c |
T |
C |
16: 57,276,780 (GRCm38) |
N139S |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,113,133 (GRCm38) |
|
probably null |
Het |
| Trim66 |
T |
C |
7: 109,475,839 (GRCm38) |
E405G |
probably damaging |
Het |
| Trpc4 |
T |
A |
3: 54,279,994 (GRCm38) |
F456I |
probably benign |
Het |
| Tspo2 |
T |
C |
17: 48,448,790 (GRCm38) |
D108G |
possibly damaging |
Het |
| Tyk2 |
A |
T |
9: 21,121,554 (GRCm38) |
C304* |
probably null |
Het |
| Vgll4 |
A |
T |
6: 114,862,795 (GRCm38) |
S185T |
probably benign |
Het |
| Vmn2r94 |
A |
C |
17: 18,244,470 (GRCm38) |
S519R |
probably benign |
Het |
| Vmn2r96 |
T |
G |
17: 18,597,921 (GRCm38) |
S587A |
probably benign |
Het |
| Vps4b |
C |
A |
1: 106,778,982 (GRCm38) |
A287S |
possibly damaging |
Het |
| Yeats2 |
C |
T |
16: 20,229,564 (GRCm38) |
P1332S |
probably benign |
Het |
| Zfp507 |
C |
T |
7: 35,793,725 (GRCm38) |
R631Q |
probably damaging |
Het |
| Zswim5 |
G |
T |
4: 116,877,699 (GRCm38) |
E80D |
unknown |
Het |
|
| Other mutations in Zfp462 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00162:Zfp462
|
APN |
4 |
55,011,483 (GRCm38) |
splice site |
probably null |
|
|
IGL00421:Zfp462
|
APN |
4 |
55,023,576 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL00899:Zfp462
|
APN |
4 |
55,007,732 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01549:Zfp462
|
APN |
4 |
55,013,181 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01627:Zfp462
|
APN |
4 |
55,008,912 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL01715:Zfp462
|
APN |
4 |
55,008,586 (GRCm38) |
missense |
probably benign |
0.20 |
|
IGL01862:Zfp462
|
APN |
4 |
55,023,441 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01878:Zfp462
|
APN |
4 |
55,010,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01913:Zfp462
|
APN |
4 |
55,012,138 (GRCm38) |
missense |
probably benign |
0.04 |
|
IGL02029:Zfp462
|
APN |
4 |
55,079,395 (GRCm38) |
splice site |
probably benign |
|
|
IGL02338:Zfp462
|
APN |
4 |
55,010,292 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
IGL02552:Zfp462
|
APN |
4 |
55,010,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02623:Zfp462
|
APN |
4 |
55,012,986 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02750:Zfp462
|
APN |
4 |
55,060,236 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL02815:Zfp462
|
APN |
4 |
55,051,303 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03204:Zfp462
|
APN |
4 |
55,080,785 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
FR4304:Zfp462
|
UTSW |
4 |
55,009,758 (GRCm38) |
unclassified |
probably benign |
|
|
FR4304:Zfp462
|
UTSW |
4 |
55,009,757 (GRCm38) |
unclassified |
probably benign |
|
|
FR4737:Zfp462
|
UTSW |
4 |
55,009,760 (GRCm38) |
unclassified |
probably benign |
|
|
FR4737:Zfp462
|
UTSW |
4 |
55,009,758 (GRCm38) |
unclassified |
probably benign |
|
|
FR4976:Zfp462
|
UTSW |
4 |
55,009,761 (GRCm38) |
unclassified |
probably benign |
|
|
FR4976:Zfp462
|
UTSW |
4 |
55,009,760 (GRCm38) |
unclassified |
probably benign |
|
|
P0035:Zfp462
|
UTSW |
4 |
55,009,086 (GRCm38) |
missense |
probably benign |
|
|
R0052:Zfp462
|
UTSW |
4 |
55,011,762 (GRCm38) |
missense |
probably benign |
0.03 |
|
R0143:Zfp462
|
UTSW |
4 |
55,023,402 (GRCm38) |
splice site |
probably benign |
|
|
R0145:Zfp462
|
UTSW |
4 |
55,010,529 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0315:Zfp462
|
UTSW |
4 |
55,079,314 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0349:Zfp462
|
UTSW |
4 |
55,008,768 (GRCm38) |
missense |
probably benign |
|
|
R0359:Zfp462
|
UTSW |
4 |
55,013,689 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0413:Zfp462
|
UTSW |
4 |
55,010,534 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0554:Zfp462
|
UTSW |
4 |
55,013,689 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0616:Zfp462
|
UTSW |
4 |
55,011,951 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0631:Zfp462
|
UTSW |
4 |
55,007,563 (GRCm38) |
start codon destroyed |
possibly damaging |
0.60 |
|
R1086:Zfp462
|
UTSW |
4 |
55,013,000 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1499:Zfp462
|
UTSW |
4 |
55,060,046 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1509:Zfp462
|
UTSW |
4 |
55,007,667 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1526:Zfp462
|
UTSW |
4 |
55,009,002 (GRCm38) |
missense |
probably benign |
|
|
R1541:Zfp462
|
UTSW |
4 |
55,008,928 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R1691:Zfp462
|
UTSW |
4 |
55,013,489 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R2086:Zfp462
|
UTSW |
4 |
55,010,830 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2109:Zfp462
|
UTSW |
4 |
55,008,496 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2148:Zfp462
|
UTSW |
4 |
55,013,670 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2179:Zfp462
|
UTSW |
4 |
55,009,524 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R2325:Zfp462
|
UTSW |
4 |
55,013,712 (GRCm38) |
missense |
probably benign |
|
|
R2352:Zfp462
|
UTSW |
4 |
55,008,313 (GRCm38) |
missense |
probably null |
|
|
R2566:Zfp462
|
UTSW |
4 |
55,008,522 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3879:Zfp462
|
UTSW |
4 |
55,060,095 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3969:Zfp462
|
UTSW |
4 |
55,012,402 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4273:Zfp462
|
UTSW |
4 |
55,008,411 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4413:Zfp462
|
UTSW |
4 |
55,012,672 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4510:Zfp462
|
UTSW |
4 |
55,008,934 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4511:Zfp462
|
UTSW |
4 |
55,008,934 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4609:Zfp462
|
UTSW |
4 |
55,011,889 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4632:Zfp462
|
UTSW |
4 |
55,012,981 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4649:Zfp462
|
UTSW |
4 |
55,009,349 (GRCm38) |
missense |
probably benign |
|
|
R4682:Zfp462
|
UTSW |
4 |
55,011,376 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4696:Zfp462
|
UTSW |
4 |
55,008,612 (GRCm38) |
missense |
probably benign |
|
|
R4744:Zfp462
|
UTSW |
4 |
55,011,598 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4747:Zfp462
|
UTSW |
4 |
55,013,476 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4819:Zfp462
|
UTSW |
4 |
55,060,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4827:Zfp462
|
UTSW |
4 |
55,012,213 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4854:Zfp462
|
UTSW |
4 |
55,010,668 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4879:Zfp462
|
UTSW |
4 |
55,009,444 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4891:Zfp462
|
UTSW |
4 |
55,060,055 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4993:Zfp462
|
UTSW |
4 |
55,051,204 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R5118:Zfp462
|
UTSW |
4 |
55,010,667 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5171:Zfp462
|
UTSW |
4 |
55,016,986 (GRCm38) |
splice site |
probably null |
|
|
R5173:Zfp462
|
UTSW |
4 |
55,011,115 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5221:Zfp462
|
UTSW |
4 |
55,016,887 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R5268:Zfp462
|
UTSW |
4 |
55,012,299 (GRCm38) |
missense |
probably benign |
|
|
R5314:Zfp462
|
UTSW |
4 |
55,013,178 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5429:Zfp462
|
UTSW |
4 |
55,060,077 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5518:Zfp462
|
UTSW |
4 |
55,009,818 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5525:Zfp462
|
UTSW |
4 |
55,050,281 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R5620:Zfp462
|
UTSW |
4 |
55,013,464 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5775:Zfp462
|
UTSW |
4 |
55,010,590 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6126:Zfp462
|
UTSW |
4 |
55,023,573 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6280:Zfp462
|
UTSW |
4 |
55,010,253 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6325:Zfp462
|
UTSW |
4 |
55,080,680 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6542:Zfp462
|
UTSW |
4 |
55,023,433 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6612:Zfp462
|
UTSW |
4 |
55,012,324 (GRCm38) |
splice site |
probably null |
|
|
R6663:Zfp462
|
UTSW |
4 |
55,008,933 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R6872:Zfp462
|
UTSW |
4 |
55,012,326 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6889:Zfp462
|
UTSW |
4 |
55,007,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6896:Zfp462
|
UTSW |
4 |
55,009,544 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R6913:Zfp462
|
UTSW |
4 |
55,007,775 (GRCm38) |
missense |
probably benign |
0.25 |
|
R6988:Zfp462
|
UTSW |
4 |
55,080,716 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7131:Zfp462
|
UTSW |
4 |
55,009,380 (GRCm38) |
missense |
probably benign |
|
|
R7151:Zfp462
|
UTSW |
4 |
55,051,271 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7684:Zfp462
|
UTSW |
4 |
55,008,908 (GRCm38) |
missense |
probably benign |
|
|
R7741:Zfp462
|
UTSW |
4 |
55,008,637 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7750:Zfp462
|
UTSW |
4 |
55,016,958 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7812:Zfp462
|
UTSW |
4 |
55,008,509 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7863:Zfp462
|
UTSW |
4 |
55,007,747 (GRCm38) |
missense |
probably benign |
|
|
R7898:Zfp462
|
UTSW |
4 |
55,012,995 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7993:Zfp462
|
UTSW |
4 |
55,011,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7995:Zfp462
|
UTSW |
4 |
55,011,907 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8023:Zfp462
|
UTSW |
4 |
55,073,106 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8394:Zfp462
|
UTSW |
4 |
55,011,862 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8669:Zfp462
|
UTSW |
4 |
55,051,313 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8877:Zfp462
|
UTSW |
4 |
55,011,097 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8980:Zfp462
|
UTSW |
4 |
55,009,681 (GRCm38) |
unclassified |
probably benign |
|
|
R9023:Zfp462
|
UTSW |
4 |
55,007,563 (GRCm38) |
start codon destroyed |
probably null |
0.00 |
|
R9243:Zfp462
|
UTSW |
4 |
55,009,595 (GRCm38) |
nonsense |
probably null |
|
|
R9378:Zfp462
|
UTSW |
4 |
55,011,510 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9417:Zfp462
|
UTSW |
4 |
55,016,988 (GRCm38) |
missense |
probably benign |
0.26 |
|
R9476:Zfp462
|
UTSW |
4 |
55,080,735 (GRCm38) |
missense |
probably benign |
|
|
R9510:Zfp462
|
UTSW |
4 |
55,080,735 (GRCm38) |
missense |
probably benign |
|
|
R9610:Zfp462
|
UTSW |
4 |
55,009,545 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R9628:Zfp462
|
UTSW |
4 |
55,009,423 (GRCm38) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCTTACAAGTGCACCATGTGTAG -3'
(R):5'- AACCTCGATCTCGACTTCGTTG -3'
Sequencing Primer
(F):5'- GTTATTCCACCATGACTCTGAAAGGG -3'
(R):5'- CGATCTCGACTTCGTTGTCATC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation