Incidental Mutation 'R1843:Anks1b'
| ID |
207448 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anks1b
|
| Ensembl Gene |
ENSMUSG00000058589 |
| Gene Name |
ankyrin repeat and sterile alpha motif domain containing 1B |
| Synonyms |
C030032C09Rik, AIDA-1b, LOC380650, Gm10937, E530015N03Rik |
| MMRRC Submission |
039868-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1843 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
89873509-90973300 bp(+) (GRCm38) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to A
at 90512889 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000138539
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099368]
[ENSMUST00000099368]
[ENSMUST00000182907]
[ENSMUST00000182936]
[ENSMUST00000183156]
[ENSMUST00000183156]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000099368
|
| SMART Domains |
Protein: ENSMUSP00000096968
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
931 |
4.44e-1 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000099368
|
| SMART Domains |
Protein: ENSMUSP00000096968
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
931 |
4.44e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182907
|
| SMART Domains |
Protein: ENSMUSP00000138614
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
45 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182936
|
| SMART Domains |
Protein: ENSMUSP00000138209
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
5.03e2 |
SMART |
|
low complexity region
|
464 |
479 |
N/A |
INTRINSIC |
|
low complexity region
|
517 |
543 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183156
|
| SMART Domains |
Protein: ENSMUSP00000138539
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
948 |
5.66e-17 |
SMART |
|
low complexity region
|
968 |
983 |
N/A |
INTRINSIC |
|
PTB
|
1056 |
1194 |
2.94e-38 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000183156
|
| SMART Domains |
Protein: ENSMUSP00000138539
Gene: ENSMUSG00000058589
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
21 |
46 |
N/A |
INTRINSIC |
|
ANK
|
58 |
87 |
1.88e-5 |
SMART |
|
ANK
|
91 |
123 |
3.13e-2 |
SMART |
|
ANK
|
127 |
156 |
6.92e-4 |
SMART |
|
ANK
|
160 |
189 |
3.08e-1 |
SMART |
|
ANK
|
193 |
222 |
1.43e-5 |
SMART |
|
ANK
|
225 |
254 |
4.75e-2 |
SMART |
|
low complexity region
|
498 |
513 |
N/A |
INTRINSIC |
|
low complexity region
|
551 |
577 |
N/A |
INTRINSIC |
|
low complexity region
|
659 |
670 |
N/A |
INTRINSIC |
|
SAM
|
806 |
875 |
2.06e-19 |
SMART |
|
SAM
|
880 |
948 |
5.66e-17 |
SMART |
|
low complexity region
|
968 |
983 |
N/A |
INTRINSIC |
|
PTB
|
1056 |
1194 |
2.94e-38 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a conditional allele activated in neurons alters hippocampal synaptic transmission. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
C |
T |
8: 105,708,974 (GRCm38) |
T88M |
probably damaging |
Het |
| 9130011E15Rik |
A |
C |
19: 45,975,252 (GRCm38) |
S42R |
probably benign |
Het |
| 9430038I01Rik |
A |
G |
7: 137,377,066 (GRCm38) |
|
probably benign |
Het |
| Adgra3 |
A |
C |
5: 49,961,492 (GRCm38) |
S905A |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,544,533 (GRCm38) |
Y1618H |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,673,314 (GRCm38) |
T26A |
probably benign |
Het |
| Ankrd13d |
T |
C |
19: 4,271,595 (GRCm38) |
K360E |
probably damaging |
Het |
| Apob |
T |
C |
12: 8,007,602 (GRCm38) |
F2028S |
possibly damaging |
Het |
| Arap3 |
G |
A |
18: 37,975,583 (GRCm38) |
R1265W |
probably damaging |
Het |
| Arhgef37 |
A |
G |
18: 61,518,050 (GRCm38) |
Y135H |
probably damaging |
Het |
| Atp1a1 |
T |
C |
3: 101,582,017 (GRCm38) |
T760A |
probably benign |
Het |
| Cdc42bpb |
T |
A |
12: 111,322,821 (GRCm38) |
M497L |
probably benign |
Het |
| Ces5a |
C |
T |
8: 93,514,231 (GRCm38) |
V413M |
probably damaging |
Het |
| Chd5 |
A |
T |
4: 152,385,806 (GRCm38) |
Y1903F |
probably damaging |
Het |
| Chd9 |
T |
A |
8: 91,010,794 (GRCm38) |
N1500K |
probably benign |
Het |
| Chmp7 |
G |
T |
14: 69,719,799 (GRCm38) |
D303E |
probably benign |
Het |
| Chrnb4 |
A |
T |
9: 55,034,818 (GRCm38) |
Y391N |
possibly damaging |
Het |
| Crtc1 |
T |
C |
8: 70,388,152 (GRCm38) |
T475A |
probably benign |
Het |
| Cyp2c69 |
A |
G |
19: 39,877,528 (GRCm38) |
I207T |
probably benign |
Het |
| Dcp1a |
A |
G |
14: 30,518,983 (GRCm38) |
E250G |
probably damaging |
Het |
| Ddx20 |
T |
C |
3: 105,679,082 (GRCm38) |
Q649R |
probably benign |
Het |
| Defb12 |
T |
A |
8: 19,112,738 (GRCm38) |
K59N |
probably damaging |
Het |
| Dpy19l3 |
A |
T |
7: 35,729,760 (GRCm38) |
I85N |
probably damaging |
Het |
| Duox2 |
C |
T |
2: 122,292,258 (GRCm38) |
|
probably null |
Het |
| E430018J23Rik |
A |
C |
7: 127,391,488 (GRCm38) |
D442E |
probably benign |
Het |
| Ebi3 |
T |
A |
17: 55,956,679 (GRCm38) |
Y197N |
probably damaging |
Het |
| Emc1 |
G |
A |
4: 139,375,512 (GRCm38) |
R994Q |
probably benign |
Het |
| Ercc6 |
G |
T |
14: 32,546,820 (GRCm38) |
M530I |
probably damaging |
Het |
| Evl |
T |
A |
12: 108,652,996 (GRCm38) |
D70E |
probably damaging |
Het |
| Fam35a |
A |
G |
14: 34,267,803 (GRCm38) |
I382T |
probably benign |
Het |
| Fbln2 |
A |
G |
6: 91,265,775 (GRCm38) |
N819S |
probably damaging |
Het |
| Foxk2 |
A |
G |
11: 121,285,537 (GRCm38) |
I170V |
probably benign |
Het |
| Gfm1 |
T |
C |
3: 67,435,610 (GRCm38) |
V159A |
probably damaging |
Het |
| Gm10837 |
A |
G |
14: 122,490,765 (GRCm38) |
T18A |
unknown |
Het |
| Gm12887 |
A |
T |
4: 121,622,030 (GRCm38) |
V25E |
probably damaging |
Het |
| Hectd4 |
A |
G |
5: 121,297,180 (GRCm38) |
H985R |
possibly damaging |
Het |
| Hsfy2 |
A |
G |
1: 56,636,632 (GRCm38) |
Y249H |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,545,567 (GRCm38) |
V2639A |
probably damaging |
Het |
| Igf2r |
A |
G |
17: 12,704,270 (GRCm38) |
|
probably null |
Het |
| Invs |
T |
A |
4: 48,422,035 (GRCm38) |
I889N |
probably damaging |
Het |
| Kcnq1 |
A |
T |
7: 143,183,120 (GRCm38) |
M209L |
probably benign |
Het |
| Klra7 |
A |
G |
6: 130,229,994 (GRCm38) |
I48T |
possibly damaging |
Het |
| Krt26 |
CTAGTA |
CTA |
11: 99,333,526 (GRCm38) |
|
probably benign |
Het |
| Lrif1 |
T |
A |
3: 106,732,811 (GRCm38) |
V404D |
probably damaging |
Het |
| Lrriq1 |
T |
A |
10: 103,227,173 (GRCm38) |
|
probably null |
Het |
| Lypd6 |
T |
A |
2: 50,188,762 (GRCm38) |
I90N |
possibly damaging |
Het |
| Mbp |
A |
G |
18: 82,584,122 (GRCm38) |
D174G |
probably damaging |
Het |
| Megf9 |
G |
T |
4: 70,534,785 (GRCm38) |
P13Q |
probably damaging |
Het |
| Myo15b |
A |
T |
11: 115,869,586 (GRCm38) |
T1155S |
probably benign |
Het |
| Nlrp6 |
T |
A |
7: 140,923,093 (GRCm38) |
C371S |
probably damaging |
Het |
| Nosip |
T |
A |
7: 45,077,309 (GRCm38) |
|
probably null |
Het |
| Nox3 |
G |
T |
17: 3,669,878 (GRCm38) |
P344H |
probably damaging |
Het |
| Nup210l |
T |
C |
3: 90,172,086 (GRCm38) |
V959A |
probably damaging |
Het |
| Olfr1360 |
C |
A |
13: 21,674,672 (GRCm38) |
V91L |
probably benign |
Het |
| Olfr1475 |
A |
G |
19: 13,479,931 (GRCm38) |
I89T |
probably benign |
Het |
| Olfr175-ps1 |
T |
A |
16: 58,824,077 (GRCm38) |
I211F |
probably damaging |
Het |
| Olfr267 |
T |
C |
4: 58,785,384 (GRCm38) |
I113V |
probably benign |
Het |
| Olfr959 |
A |
G |
9: 39,572,735 (GRCm38) |
Y175H |
possibly damaging |
Het |
| Osbpl3 |
A |
C |
6: 50,370,143 (GRCm38) |
S25A |
probably damaging |
Het |
| Otog |
G |
A |
7: 46,246,283 (GRCm38) |
C107Y |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,784,491 (GRCm38) |
R260C |
probably damaging |
Het |
| Pbrm1 |
A |
T |
14: 31,038,957 (GRCm38) |
I224F |
probably damaging |
Het |
| Pcdh1 |
T |
A |
18: 38,192,225 (GRCm38) |
|
probably null |
Het |
| Pcnx |
T |
C |
12: 81,980,935 (GRCm38) |
L1585P |
probably damaging |
Het |
| Pde4c |
C |
T |
8: 70,747,950 (GRCm38) |
H362Y |
probably damaging |
Het |
| Pdlim2 |
C |
T |
14: 70,164,779 (GRCm38) |
R296H |
probably damaging |
Het |
| Pgm2 |
A |
T |
4: 99,961,478 (GRCm38) |
Q90L |
probably damaging |
Het |
| Phlpp1 |
A |
G |
1: 106,343,505 (GRCm38) |
H814R |
probably benign |
Het |
| Pknox2 |
A |
T |
9: 36,954,831 (GRCm38) |
M5K |
possibly damaging |
Het |
| Pole |
G |
A |
5: 110,330,835 (GRCm38) |
|
probably null |
Het |
| Polr1b |
A |
G |
2: 129,102,966 (GRCm38) |
I61V |
probably benign |
Het |
| Prelp |
T |
C |
1: 133,914,757 (GRCm38) |
K217E |
probably damaging |
Het |
| Prkce |
C |
T |
17: 86,475,546 (GRCm38) |
Q202* |
probably null |
Het |
| Psmd2 |
T |
G |
16: 20,656,582 (GRCm38) |
M370R |
probably benign |
Het |
| Rimklb |
A |
T |
6: 122,464,009 (GRCm38) |
H68Q |
probably damaging |
Het |
| Rnasel |
A |
G |
1: 153,754,674 (GRCm38) |
D312G |
possibly damaging |
Het |
| Rxrg |
A |
T |
1: 167,598,752 (GRCm38) |
M1L |
probably benign |
Het |
| Scrn1 |
A |
G |
6: 54,522,841 (GRCm38) |
F220L |
possibly damaging |
Het |
| Scyl3 |
A |
G |
1: 163,950,675 (GRCm38) |
S461G |
probably benign |
Het |
| Serpina1c |
T |
A |
12: 103,895,023 (GRCm38) |
T411S |
probably benign |
Het |
| Serpinb6d |
C |
T |
13: 33,671,381 (GRCm38) |
P346L |
probably benign |
Het |
| Slc9a3r2 |
C |
T |
17: 24,641,719 (GRCm38) |
S150N |
possibly damaging |
Het |
| Spg21 |
G |
T |
9: 65,465,336 (GRCm38) |
V17F |
probably damaging |
Het |
| Spink5 |
A |
T |
18: 43,999,891 (GRCm38) |
M525L |
probably benign |
Het |
| Sun2 |
T |
C |
15: 79,737,563 (GRCm38) |
T155A |
probably benign |
Het |
| Tchh |
T |
A |
3: 93,446,780 (GRCm38) |
F1176I |
unknown |
Het |
| Tex15 |
T |
A |
8: 33,576,654 (GRCm38) |
D2037E |
probably benign |
Het |
| Tfdp2 |
T |
C |
9: 96,317,804 (GRCm38) |
C392R |
possibly damaging |
Het |
| Tmem30c |
T |
C |
16: 57,276,780 (GRCm38) |
N139S |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,113,133 (GRCm38) |
|
probably null |
Het |
| Trim66 |
T |
C |
7: 109,475,839 (GRCm38) |
E405G |
probably damaging |
Het |
| Trpc4 |
T |
A |
3: 54,279,994 (GRCm38) |
F456I |
probably benign |
Het |
| Tspo2 |
T |
C |
17: 48,448,790 (GRCm38) |
D108G |
possibly damaging |
Het |
| Tyk2 |
A |
T |
9: 21,121,554 (GRCm38) |
C304* |
probably null |
Het |
| Vgll4 |
A |
T |
6: 114,862,795 (GRCm38) |
S185T |
probably benign |
Het |
| Vmn2r94 |
A |
C |
17: 18,244,470 (GRCm38) |
S519R |
probably benign |
Het |
| Vmn2r96 |
T |
G |
17: 18,597,921 (GRCm38) |
S587A |
probably benign |
Het |
| Vps4b |
C |
A |
1: 106,778,982 (GRCm38) |
A287S |
possibly damaging |
Het |
| Yeats2 |
C |
T |
16: 20,229,564 (GRCm38) |
P1332S |
probably benign |
Het |
| Zfp462 |
T |
G |
4: 55,010,010 (GRCm38) |
S659A |
possibly damaging |
Het |
| Zfp507 |
C |
T |
7: 35,793,725 (GRCm38) |
R631Q |
probably damaging |
Het |
| Zswim5 |
G |
T |
4: 116,877,699 (GRCm38) |
E80D |
unknown |
Het |
|
| Other mutations in Anks1b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01669:Anks1b
|
APN |
10 |
90,897,238 (GRCm38) |
splice site |
probably benign |
|
|
IGL01890:Anks1b
|
APN |
10 |
90,644,527 (GRCm38) |
missense |
probably benign |
0.15 |
|
IGL01966:Anks1b
|
APN |
10 |
90,895,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02176:Anks1b
|
APN |
10 |
90,042,668 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02205:Anks1b
|
APN |
10 |
90,071,094 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02465:Anks1b
|
APN |
10 |
90,163,265 (GRCm38) |
nonsense |
probably null |
|
|
IGL02534:Anks1b
|
APN |
10 |
90,895,117 (GRCm38) |
missense |
probably benign |
0.45 |
|
IGL02554:Anks1b
|
APN |
10 |
90,921,378 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02820:Anks1b
|
APN |
10 |
90,077,059 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03164:Anks1b
|
APN |
10 |
90,042,692 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0096:Anks1b
|
UTSW |
10 |
90,074,062 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R0482:Anks1b
|
UTSW |
10 |
90,359,195 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0542:Anks1b
|
UTSW |
10 |
90,073,967 (GRCm38) |
splice site |
probably benign |
|
|
R0848:Anks1b
|
UTSW |
10 |
90,071,125 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1056:Anks1b
|
UTSW |
10 |
90,921,429 (GRCm38) |
splice site |
probably null |
|
|
R1398:Anks1b
|
UTSW |
10 |
90,050,029 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1446:Anks1b
|
UTSW |
10 |
90,511,073 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1548:Anks1b
|
UTSW |
10 |
90,049,985 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R1551:Anks1b
|
UTSW |
10 |
90,076,981 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1607:Anks1b
|
UTSW |
10 |
90,042,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1667:Anks1b
|
UTSW |
10 |
90,511,184 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1701:Anks1b
|
UTSW |
10 |
90,049,954 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1899:Anks1b
|
UTSW |
10 |
90,260,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1957:Anks1b
|
UTSW |
10 |
90,049,930 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2036:Anks1b
|
UTSW |
10 |
90,969,853 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2279:Anks1b
|
UTSW |
10 |
90,050,096 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2280:Anks1b
|
UTSW |
10 |
90,966,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2937:Anks1b
|
UTSW |
10 |
90,077,066 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3739:Anks1b
|
UTSW |
10 |
90,033,216 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4061:Anks1b
|
UTSW |
10 |
90,307,622 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R4459:Anks1b
|
UTSW |
10 |
90,510,844 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4479:Anks1b
|
UTSW |
10 |
90,049,892 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4510:Anks1b
|
UTSW |
10 |
90,510,790 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4511:Anks1b
|
UTSW |
10 |
90,510,790 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4780:Anks1b
|
UTSW |
10 |
89,873,732 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4785:Anks1b
|
UTSW |
10 |
90,914,750 (GRCm38) |
missense |
probably null |
0.88 |
|
R4790:Anks1b
|
UTSW |
10 |
90,163,275 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5012:Anks1b
|
UTSW |
10 |
90,359,137 (GRCm38) |
missense |
probably benign |
0.06 |
|
R5400:Anks1b
|
UTSW |
10 |
90,512,824 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5586:Anks1b
|
UTSW |
10 |
90,077,064 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5687:Anks1b
|
UTSW |
10 |
90,914,711 (GRCm38) |
missense |
probably benign |
0.03 |
|
R5899:Anks1b
|
UTSW |
10 |
90,923,517 (GRCm38) |
splice site |
probably null |
|
|
R5917:Anks1b
|
UTSW |
10 |
90,576,941 (GRCm38) |
intron |
probably benign |
|
|
R5999:Anks1b
|
UTSW |
10 |
90,359,048 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6080:Anks1b
|
UTSW |
10 |
90,966,349 (GRCm38) |
nonsense |
probably null |
|
|
R6216:Anks1b
|
UTSW |
10 |
90,260,756 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6265:Anks1b
|
UTSW |
10 |
90,941,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6298:Anks1b
|
UTSW |
10 |
90,680,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6337:Anks1b
|
UTSW |
10 |
90,921,296 (GRCm38) |
missense |
probably benign |
0.27 |
|
R6522:Anks1b
|
UTSW |
10 |
90,897,327 (GRCm38) |
intron |
probably benign |
|
|
R6843:Anks1b
|
UTSW |
10 |
90,948,598 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6852:Anks1b
|
UTSW |
10 |
90,260,654 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6933:Anks1b
|
UTSW |
10 |
90,069,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7114:Anks1b
|
UTSW |
10 |
90,307,698 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7211:Anks1b
|
UTSW |
10 |
90,511,070 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7241:Anks1b
|
UTSW |
10 |
90,512,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7264:Anks1b
|
UTSW |
10 |
90,512,870 (GRCm38) |
missense |
probably benign |
0.08 |
|
R7325:Anks1b
|
UTSW |
10 |
90,941,432 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7392:Anks1b
|
UTSW |
10 |
90,680,786 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R7578:Anks1b
|
UTSW |
10 |
90,049,927 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7604:Anks1b
|
UTSW |
10 |
90,260,846 (GRCm38) |
splice site |
probably null |
|
|
R7633:Anks1b
|
UTSW |
10 |
90,948,584 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7881:Anks1b
|
UTSW |
10 |
90,967,018 (GRCm38) |
missense |
probably benign |
0.07 |
|
R7910:Anks1b
|
UTSW |
10 |
90,680,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7941:Anks1b
|
UTSW |
10 |
90,577,155 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8045:Anks1b
|
UTSW |
10 |
90,680,860 (GRCm38) |
missense |
probably benign |
|
|
R8146:Anks1b
|
UTSW |
10 |
90,307,698 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8176:Anks1b
|
UTSW |
10 |
90,069,491 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8535:Anks1b
|
UTSW |
10 |
90,948,631 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8681:Anks1b
|
UTSW |
10 |
90,050,006 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9300:Anks1b
|
UTSW |
10 |
90,577,104 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R9469:Anks1b
|
UTSW |
10 |
90,897,343 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R9541:Anks1b
|
UTSW |
10 |
90,577,085 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9550:Anks1b
|
UTSW |
10 |
90,576,498 (GRCm38) |
start codon destroyed |
probably null |
|
|
R9653:Anks1b
|
UTSW |
10 |
90,510,662 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF004:Anks1b
|
UTSW |
10 |
90,033,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF008:Anks1b
|
UTSW |
10 |
90,033,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF017:Anks1b
|
UTSW |
10 |
90,033,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF018:Anks1b
|
UTSW |
10 |
90,033,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF023:Anks1b
|
UTSW |
10 |
90,033,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0064:Anks1b
|
UTSW |
10 |
90,512,845 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGTGGTAGTAGCACCAAG -3'
(R):5'- CTGACATCATAAAAGAGCAACGTGG -3'
Sequencing Primer
(F):5'- TGTGGTAGTAGCACCAAGAATATATG -3'
(R):5'- GTGGGGAAAAATTCTCAATTTGCCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation