Incidental Mutation 'R1843:Lrriq1'
| ID |
207450 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Lrriq1
|
| Ensembl Gene |
ENSMUSG00000019892 |
| Gene Name |
leucine-rich repeats and IQ motif containing 1 |
| Synonyms |
LOC380658, 4930503E15Rik, Gm1557 |
| MMRRC Submission |
039868-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.097)
|
| Stock # |
R1843 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
103046031-103236322 bp(-) (GRCm38) |
| Type of Mutation |
splice site (3 bp from exon) |
| DNA Base Change (assembly) |
T to A
at 103227173 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131419
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020043]
[ENSMUST00000123364]
[ENSMUST00000166240]
|
| AlphaFold |
Q0P5X1 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000020043
|
| SMART Domains |
Protein: ENSMUSP00000020043
Gene: ENSMUSG00000019892
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
1e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000123364
|
| SMART Domains |
Protein: ENSMUSP00000119783
Gene: ENSMUSG00000019892
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
Blast:IQ
|
290 |
312 |
6e-6 |
BLAST |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000166240
|
| SMART Domains |
Protein: ENSMUSP00000131419
Gene: ENSMUSG00000019892
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
11 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
35 |
48 |
N/A |
INTRINSIC |
|
coiled coil region
|
183 |
286 |
N/A |
INTRINSIC |
|
IQ
|
290 |
312 |
9.78e1 |
SMART |
|
coiled coil region
|
314 |
390 |
N/A |
INTRINSIC |
|
low complexity region
|
550 |
559 |
N/A |
INTRINSIC |
|
LRR
|
873 |
894 |
2.14e1 |
SMART |
|
LRR
|
895 |
917 |
4.45e1 |
SMART |
|
LRR
|
984 |
1005 |
2.03e2 |
SMART |
|
LRR
|
1029 |
1052 |
3.65e0 |
SMART |
|
low complexity region
|
1244 |
1258 |
N/A |
INTRINSIC |
|
IQ
|
1279 |
1301 |
5.61e1 |
SMART |
|
IQ
|
1339 |
1361 |
6.7e-3 |
SMART |
|
low complexity region
|
1369 |
1394 |
N/A |
INTRINSIC |
|
low complexity region
|
1502 |
1518 |
N/A |
INTRINSIC |
|
low complexity region
|
1528 |
1543 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
C |
T |
8: 105,708,974 (GRCm38) |
T88M |
probably damaging |
Het |
| 9130011E15Rik |
A |
C |
19: 45,975,252 (GRCm38) |
S42R |
probably benign |
Het |
| 9430038I01Rik |
A |
G |
7: 137,377,066 (GRCm38) |
|
probably benign |
Het |
| Adgra3 |
A |
C |
5: 49,961,492 (GRCm38) |
S905A |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,544,533 (GRCm38) |
Y1618H |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,673,314 (GRCm38) |
T26A |
probably benign |
Het |
| Ankrd13d |
T |
C |
19: 4,271,595 (GRCm38) |
K360E |
probably damaging |
Het |
| Anks1b |
T |
A |
10: 90,512,889 (GRCm38) |
|
probably null |
Het |
| Apob |
T |
C |
12: 8,007,602 (GRCm38) |
F2028S |
possibly damaging |
Het |
| Arap3 |
G |
A |
18: 37,975,583 (GRCm38) |
R1265W |
probably damaging |
Het |
| Arhgef37 |
A |
G |
18: 61,518,050 (GRCm38) |
Y135H |
probably damaging |
Het |
| Atp1a1 |
T |
C |
3: 101,582,017 (GRCm38) |
T760A |
probably benign |
Het |
| Cdc42bpb |
T |
A |
12: 111,322,821 (GRCm38) |
M497L |
probably benign |
Het |
| Ces5a |
C |
T |
8: 93,514,231 (GRCm38) |
V413M |
probably damaging |
Het |
| Chd5 |
A |
T |
4: 152,385,806 (GRCm38) |
Y1903F |
probably damaging |
Het |
| Chd9 |
T |
A |
8: 91,010,794 (GRCm38) |
N1500K |
probably benign |
Het |
| Chmp7 |
G |
T |
14: 69,719,799 (GRCm38) |
D303E |
probably benign |
Het |
| Chrnb4 |
A |
T |
9: 55,034,818 (GRCm38) |
Y391N |
possibly damaging |
Het |
| Crtc1 |
T |
C |
8: 70,388,152 (GRCm38) |
T475A |
probably benign |
Het |
| Cyp2c69 |
A |
G |
19: 39,877,528 (GRCm38) |
I207T |
probably benign |
Het |
| Dcp1a |
A |
G |
14: 30,518,983 (GRCm38) |
E250G |
probably damaging |
Het |
| Ddx20 |
T |
C |
3: 105,679,082 (GRCm38) |
Q649R |
probably benign |
Het |
| Defb12 |
T |
A |
8: 19,112,738 (GRCm38) |
K59N |
probably damaging |
Het |
| Dpy19l3 |
A |
T |
7: 35,729,760 (GRCm38) |
I85N |
probably damaging |
Het |
| Duox2 |
C |
T |
2: 122,292,258 (GRCm38) |
|
probably null |
Het |
| E430018J23Rik |
A |
C |
7: 127,391,488 (GRCm38) |
D442E |
probably benign |
Het |
| Ebi3 |
T |
A |
17: 55,956,679 (GRCm38) |
Y197N |
probably damaging |
Het |
| Emc1 |
G |
A |
4: 139,375,512 (GRCm38) |
R994Q |
probably benign |
Het |
| Ercc6 |
G |
T |
14: 32,546,820 (GRCm38) |
M530I |
probably damaging |
Het |
| Evl |
T |
A |
12: 108,652,996 (GRCm38) |
D70E |
probably damaging |
Het |
| Fam35a |
A |
G |
14: 34,267,803 (GRCm38) |
I382T |
probably benign |
Het |
| Fbln2 |
A |
G |
6: 91,265,775 (GRCm38) |
N819S |
probably damaging |
Het |
| Foxk2 |
A |
G |
11: 121,285,537 (GRCm38) |
I170V |
probably benign |
Het |
| Gfm1 |
T |
C |
3: 67,435,610 (GRCm38) |
V159A |
probably damaging |
Het |
| Gm10837 |
A |
G |
14: 122,490,765 (GRCm38) |
T18A |
unknown |
Het |
| Gm12887 |
A |
T |
4: 121,622,030 (GRCm38) |
V25E |
probably damaging |
Het |
| Hectd4 |
A |
G |
5: 121,297,180 (GRCm38) |
H985R |
possibly damaging |
Het |
| Hsfy2 |
A |
G |
1: 56,636,632 (GRCm38) |
Y249H |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,545,567 (GRCm38) |
V2639A |
probably damaging |
Het |
| Igf2r |
A |
G |
17: 12,704,270 (GRCm38) |
|
probably null |
Het |
| Invs |
T |
A |
4: 48,422,035 (GRCm38) |
I889N |
probably damaging |
Het |
| Kcnq1 |
A |
T |
7: 143,183,120 (GRCm38) |
M209L |
probably benign |
Het |
| Klra7 |
A |
G |
6: 130,229,994 (GRCm38) |
I48T |
possibly damaging |
Het |
| Krt26 |
CTAGTA |
CTA |
11: 99,333,526 (GRCm38) |
|
probably benign |
Het |
| Lrif1 |
T |
A |
3: 106,732,811 (GRCm38) |
V404D |
probably damaging |
Het |
| Lypd6 |
T |
A |
2: 50,188,762 (GRCm38) |
I90N |
possibly damaging |
Het |
| Mbp |
A |
G |
18: 82,584,122 (GRCm38) |
D174G |
probably damaging |
Het |
| Megf9 |
G |
T |
4: 70,534,785 (GRCm38) |
P13Q |
probably damaging |
Het |
| Myo15b |
A |
T |
11: 115,869,586 (GRCm38) |
T1155S |
probably benign |
Het |
| Nlrp6 |
T |
A |
7: 140,923,093 (GRCm38) |
C371S |
probably damaging |
Het |
| Nosip |
T |
A |
7: 45,077,309 (GRCm38) |
|
probably null |
Het |
| Nox3 |
G |
T |
17: 3,669,878 (GRCm38) |
P344H |
probably damaging |
Het |
| Nup210l |
T |
C |
3: 90,172,086 (GRCm38) |
V959A |
probably damaging |
Het |
| Olfr1360 |
C |
A |
13: 21,674,672 (GRCm38) |
V91L |
probably benign |
Het |
| Olfr1475 |
A |
G |
19: 13,479,931 (GRCm38) |
I89T |
probably benign |
Het |
| Olfr175-ps1 |
T |
A |
16: 58,824,077 (GRCm38) |
I211F |
probably damaging |
Het |
| Olfr267 |
T |
C |
4: 58,785,384 (GRCm38) |
I113V |
probably benign |
Het |
| Olfr959 |
A |
G |
9: 39,572,735 (GRCm38) |
Y175H |
possibly damaging |
Het |
| Osbpl3 |
A |
C |
6: 50,370,143 (GRCm38) |
S25A |
probably damaging |
Het |
| Otog |
G |
A |
7: 46,246,283 (GRCm38) |
C107Y |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,784,491 (GRCm38) |
R260C |
probably damaging |
Het |
| Pbrm1 |
A |
T |
14: 31,038,957 (GRCm38) |
I224F |
probably damaging |
Het |
| Pcdh1 |
T |
A |
18: 38,192,225 (GRCm38) |
|
probably null |
Het |
| Pcnx |
T |
C |
12: 81,980,935 (GRCm38) |
L1585P |
probably damaging |
Het |
| Pde4c |
C |
T |
8: 70,747,950 (GRCm38) |
H362Y |
probably damaging |
Het |
| Pdlim2 |
C |
T |
14: 70,164,779 (GRCm38) |
R296H |
probably damaging |
Het |
| Pgm2 |
A |
T |
4: 99,961,478 (GRCm38) |
Q90L |
probably damaging |
Het |
| Phlpp1 |
A |
G |
1: 106,343,505 (GRCm38) |
H814R |
probably benign |
Het |
| Pknox2 |
A |
T |
9: 36,954,831 (GRCm38) |
M5K |
possibly damaging |
Het |
| Pole |
G |
A |
5: 110,330,835 (GRCm38) |
|
probably null |
Het |
| Polr1b |
A |
G |
2: 129,102,966 (GRCm38) |
I61V |
probably benign |
Het |
| Prelp |
T |
C |
1: 133,914,757 (GRCm38) |
K217E |
probably damaging |
Het |
| Prkce |
C |
T |
17: 86,475,546 (GRCm38) |
Q202* |
probably null |
Het |
| Psmd2 |
T |
G |
16: 20,656,582 (GRCm38) |
M370R |
probably benign |
Het |
| Rimklb |
A |
T |
6: 122,464,009 (GRCm38) |
H68Q |
probably damaging |
Het |
| Rnasel |
A |
G |
1: 153,754,674 (GRCm38) |
D312G |
possibly damaging |
Het |
| Rxrg |
A |
T |
1: 167,598,752 (GRCm38) |
M1L |
probably benign |
Het |
| Scrn1 |
A |
G |
6: 54,522,841 (GRCm38) |
F220L |
possibly damaging |
Het |
| Scyl3 |
A |
G |
1: 163,950,675 (GRCm38) |
S461G |
probably benign |
Het |
| Serpina1c |
T |
A |
12: 103,895,023 (GRCm38) |
T411S |
probably benign |
Het |
| Serpinb6d |
C |
T |
13: 33,671,381 (GRCm38) |
P346L |
probably benign |
Het |
| Slc9a3r2 |
C |
T |
17: 24,641,719 (GRCm38) |
S150N |
possibly damaging |
Het |
| Spg21 |
G |
T |
9: 65,465,336 (GRCm38) |
V17F |
probably damaging |
Het |
| Spink5 |
A |
T |
18: 43,999,891 (GRCm38) |
M525L |
probably benign |
Het |
| Sun2 |
T |
C |
15: 79,737,563 (GRCm38) |
T155A |
probably benign |
Het |
| Tchh |
T |
A |
3: 93,446,780 (GRCm38) |
F1176I |
unknown |
Het |
| Tex15 |
T |
A |
8: 33,576,654 (GRCm38) |
D2037E |
probably benign |
Het |
| Tfdp2 |
T |
C |
9: 96,317,804 (GRCm38) |
C392R |
possibly damaging |
Het |
| Tmem30c |
T |
C |
16: 57,276,780 (GRCm38) |
N139S |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,113,133 (GRCm38) |
|
probably null |
Het |
| Trim66 |
T |
C |
7: 109,475,839 (GRCm38) |
E405G |
probably damaging |
Het |
| Trpc4 |
T |
A |
3: 54,279,994 (GRCm38) |
F456I |
probably benign |
Het |
| Tspo2 |
T |
C |
17: 48,448,790 (GRCm38) |
D108G |
possibly damaging |
Het |
| Tyk2 |
A |
T |
9: 21,121,554 (GRCm38) |
C304* |
probably null |
Het |
| Vgll4 |
A |
T |
6: 114,862,795 (GRCm38) |
S185T |
probably benign |
Het |
| Vmn2r94 |
A |
C |
17: 18,244,470 (GRCm38) |
S519R |
probably benign |
Het |
| Vmn2r96 |
T |
G |
17: 18,597,921 (GRCm38) |
S587A |
probably benign |
Het |
| Vps4b |
C |
A |
1: 106,778,982 (GRCm38) |
A287S |
possibly damaging |
Het |
| Yeats2 |
C |
T |
16: 20,229,564 (GRCm38) |
P1332S |
probably benign |
Het |
| Zfp462 |
T |
G |
4: 55,010,010 (GRCm38) |
S659A |
possibly damaging |
Het |
| Zfp507 |
C |
T |
7: 35,793,725 (GRCm38) |
R631Q |
probably damaging |
Het |
| Zswim5 |
G |
T |
4: 116,877,699 (GRCm38) |
E80D |
unknown |
Het |
|
| Other mutations in Lrriq1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00988:Lrriq1
|
APN |
10 |
103,161,896 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01523:Lrriq1
|
APN |
10 |
103,218,116 (GRCm38) |
nonsense |
probably null |
|
|
IGL01637:Lrriq1
|
APN |
10 |
103,215,628 (GRCm38) |
missense |
probably benign |
|
|
IGL02019:Lrriq1
|
APN |
10 |
103,178,800 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL02153:Lrriq1
|
APN |
10 |
103,170,479 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02341:Lrriq1
|
APN |
10 |
103,224,941 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02343:Lrriq1
|
APN |
10 |
103,234,163 (GRCm38) |
splice site |
probably benign |
|
|
IGL02408:Lrriq1
|
APN |
10 |
103,146,281 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL02431:Lrriq1
|
APN |
10 |
103,200,639 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02540:Lrriq1
|
APN |
10 |
103,215,019 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL02558:Lrriq1
|
APN |
10 |
103,146,283 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02613:Lrriq1
|
APN |
10 |
103,144,548 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02642:Lrriq1
|
APN |
10 |
103,221,461 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
IGL03027:Lrriq1
|
APN |
10 |
103,227,196 (GRCm38) |
missense |
probably benign |
0.35 |
|
PIT4362001:Lrriq1
|
UTSW |
10 |
103,071,194 (GRCm38) |
missense |
probably benign |
0.26 |
|
R0050:Lrriq1
|
UTSW |
10 |
103,068,931 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0050:Lrriq1
|
UTSW |
10 |
103,068,931 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0068:Lrriq1
|
UTSW |
10 |
103,063,418 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0068:Lrriq1
|
UTSW |
10 |
103,063,418 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0124:Lrriq1
|
UTSW |
10 |
103,170,420 (GRCm38) |
critical splice donor site |
probably null |
|
|
R0244:Lrriq1
|
UTSW |
10 |
103,215,773 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0323:Lrriq1
|
UTSW |
10 |
103,221,289 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R0515:Lrriq1
|
UTSW |
10 |
103,068,968 (GRCm38) |
splice site |
probably null |
|
|
R0522:Lrriq1
|
UTSW |
10 |
103,161,777 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0701:Lrriq1
|
UTSW |
10 |
103,234,044 (GRCm38) |
missense |
probably benign |
|
|
R1220:Lrriq1
|
UTSW |
10 |
103,071,129 (GRCm38) |
missense |
probably benign |
0.05 |
|
R1261:Lrriq1
|
UTSW |
10 |
103,234,137 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R1262:Lrriq1
|
UTSW |
10 |
103,234,137 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R1451:Lrriq1
|
UTSW |
10 |
103,202,515 (GRCm38) |
splice site |
probably benign |
|
|
R1642:Lrriq1
|
UTSW |
10 |
103,214,456 (GRCm38) |
missense |
probably benign |
0.13 |
|
R1643:Lrriq1
|
UTSW |
10 |
103,214,824 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1647:Lrriq1
|
UTSW |
10 |
103,170,648 (GRCm38) |
nonsense |
probably null |
|
|
R1830:Lrriq1
|
UTSW |
10 |
103,161,759 (GRCm38) |
missense |
probably benign |
|
|
R2128:Lrriq1
|
UTSW |
10 |
103,214,857 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2129:Lrriq1
|
UTSW |
10 |
103,214,857 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2199:Lrriq1
|
UTSW |
10 |
103,068,913 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2354:Lrriq1
|
UTSW |
10 |
103,189,987 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2495:Lrriq1
|
UTSW |
10 |
103,202,381 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R2897:Lrriq1
|
UTSW |
10 |
103,227,250 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2898:Lrriq1
|
UTSW |
10 |
103,227,250 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2922:Lrriq1
|
UTSW |
10 |
103,214,675 (GRCm38) |
missense |
probably benign |
0.00 |
|
R2939:Lrriq1
|
UTSW |
10 |
103,144,889 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R2965:Lrriq1
|
UTSW |
10 |
103,214,900 (GRCm38) |
missense |
probably benign |
0.07 |
|
R2966:Lrriq1
|
UTSW |
10 |
103,214,900 (GRCm38) |
missense |
probably benign |
0.07 |
|
R3081:Lrriq1
|
UTSW |
10 |
103,144,889 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R3115:Lrriq1
|
UTSW |
10 |
103,170,433 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3745:Lrriq1
|
UTSW |
10 |
103,170,856 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R3813:Lrriq1
|
UTSW |
10 |
103,216,111 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3814:Lrriq1
|
UTSW |
10 |
103,216,111 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3885:Lrriq1
|
UTSW |
10 |
103,216,106 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4378:Lrriq1
|
UTSW |
10 |
103,202,364 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4632:Lrriq1
|
UTSW |
10 |
103,221,427 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4633:Lrriq1
|
UTSW |
10 |
103,200,563 (GRCm38) |
nonsense |
probably null |
|
|
R4663:Lrriq1
|
UTSW |
10 |
103,063,412 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R4702:Lrriq1
|
UTSW |
10 |
103,215,749 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4793:Lrriq1
|
UTSW |
10 |
103,170,466 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4801:Lrriq1
|
UTSW |
10 |
103,221,318 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4802:Lrriq1
|
UTSW |
10 |
103,221,318 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4815:Lrriq1
|
UTSW |
10 |
103,144,878 (GRCm38) |
missense |
probably benign |
0.10 |
|
R4872:Lrriq1
|
UTSW |
10 |
103,178,788 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R4877:Lrriq1
|
UTSW |
10 |
103,234,038 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R4894:Lrriq1
|
UTSW |
10 |
103,161,752 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R4990:Lrriq1
|
UTSW |
10 |
103,200,559 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4991:Lrriq1
|
UTSW |
10 |
103,200,559 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5011:Lrriq1
|
UTSW |
10 |
103,189,923 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5013:Lrriq1
|
UTSW |
10 |
103,189,923 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5122:Lrriq1
|
UTSW |
10 |
103,187,453 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5282:Lrriq1
|
UTSW |
10 |
103,215,345 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5311:Lrriq1
|
UTSW |
10 |
103,214,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5567:Lrriq1
|
UTSW |
10 |
103,170,596 (GRCm38) |
missense |
possibly damaging |
0.56 |
|
R5643:Lrriq1
|
UTSW |
10 |
103,215,440 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5683:Lrriq1
|
UTSW |
10 |
103,173,375 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5916:Lrriq1
|
UTSW |
10 |
103,221,382 (GRCm38) |
nonsense |
probably null |
|
|
R6008:Lrriq1
|
UTSW |
10 |
103,170,464 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6022:Lrriq1
|
UTSW |
10 |
103,215,534 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6224:Lrriq1
|
UTSW |
10 |
103,215,757 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6254:Lrriq1
|
UTSW |
10 |
103,215,451 (GRCm38) |
missense |
probably benign |
0.15 |
|
R6311:Lrriq1
|
UTSW |
10 |
103,173,393 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6460:Lrriq1
|
UTSW |
10 |
103,200,698 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6502:Lrriq1
|
UTSW |
10 |
103,227,184 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6637:Lrriq1
|
UTSW |
10 |
103,221,432 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6719:Lrriq1
|
UTSW |
10 |
103,071,116 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6736:Lrriq1
|
UTSW |
10 |
103,181,889 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6928:Lrriq1
|
UTSW |
10 |
103,214,939 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R6991:Lrriq1
|
UTSW |
10 |
103,187,458 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7174:Lrriq1
|
UTSW |
10 |
103,224,965 (GRCm38) |
missense |
probably benign |
|
|
R7241:Lrriq1
|
UTSW |
10 |
103,215,973 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7248:Lrriq1
|
UTSW |
10 |
103,223,750 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R7287:Lrriq1
|
UTSW |
10 |
103,216,016 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7402:Lrriq1
|
UTSW |
10 |
103,221,324 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R7439:Lrriq1
|
UTSW |
10 |
103,214,519 (GRCm38) |
missense |
probably benign |
0.21 |
|
R7585:Lrriq1
|
UTSW |
10 |
103,214,946 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R7611:Lrriq1
|
UTSW |
10 |
103,200,571 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R7634:Lrriq1
|
UTSW |
10 |
103,200,601 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7767:Lrriq1
|
UTSW |
10 |
103,215,954 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7809:Lrriq1
|
UTSW |
10 |
103,215,817 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7910:Lrriq1
|
UTSW |
10 |
103,215,194 (GRCm38) |
nonsense |
probably null |
|
|
R8131:Lrriq1
|
UTSW |
10 |
103,215,711 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8156:Lrriq1
|
UTSW |
10 |
103,156,335 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8211:Lrriq1
|
UTSW |
10 |
103,170,547 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8304:Lrriq1
|
UTSW |
10 |
103,234,068 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Lrriq1
|
UTSW |
10 |
103,215,053 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8500:Lrriq1
|
UTSW |
10 |
103,046,155 (GRCm38) |
missense |
|
|
|
R9013:Lrriq1
|
UTSW |
10 |
103,215,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9099:Lrriq1
|
UTSW |
10 |
103,216,003 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9155:Lrriq1
|
UTSW |
10 |
103,214,779 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9320:Lrriq1
|
UTSW |
10 |
103,221,283 (GRCm38) |
missense |
probably benign |
|
|
R9384:Lrriq1
|
UTSW |
10 |
103,170,597 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9469:Lrriq1
|
UTSW |
10 |
103,214,900 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9585:Lrriq1
|
UTSW |
10 |
103,215,389 (GRCm38) |
missense |
probably benign |
|
|
R9706:Lrriq1
|
UTSW |
10 |
103,046,041 (GRCm38) |
missense |
|
|
|
R9780:Lrriq1
|
UTSW |
10 |
103,189,963 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0026:Lrriq1
|
UTSW |
10 |
103,215,704 (GRCm38) |
nonsense |
probably null |
|
|
Z1088:Lrriq1
|
UTSW |
10 |
103,202,446 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,234,085 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,202,360 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1176:Lrriq1
|
UTSW |
10 |
103,202,359 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCATACTGACACTGACTCTG -3'
(R):5'- GGGCACTTTTACCTATTTACACAG -3'
Sequencing Primer
(F):5'- ATACTGACACTGACTCTGTGTTTTC -3'
(R):5'- GACTGCAATACTTGACATATGACC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation