Incidental Mutation 'R1843:Myo15b'
| ID |
207455 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo15b
|
| Ensembl Gene |
ENSMUSG00000034427 |
| Gene Name |
myosin XVB |
| Synonyms |
LOC217328, LOC380737, E330039G21Rik |
| MMRRC Submission |
039868-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.069)
|
| Stock # |
R1843 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
115749232-115783429 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 115760412 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 1155
(T1155S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091439
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093911]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093911
AA Change: T1155S
PolyPhen 2
Score 0.036 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000091439
Gene: ENSMUSG00000034427
AA Change: T1155S
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
1 |
640 |
2.4e-134 |
SMART |
|
IQ
|
660 |
682 |
1.03e1 |
SMART |
|
Pfam:MyTH4
|
837 |
945 |
2.1e-23 |
PFAM |
|
low complexity region
|
1050 |
1068 |
N/A |
INTRINSIC |
|
low complexity region
|
1136 |
1170 |
N/A |
INTRINSIC |
|
low complexity region
|
1207 |
1246 |
N/A |
INTRINSIC |
|
low complexity region
|
1302 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1454 |
1468 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1509 |
N/A |
INTRINSIC |
|
SH3
|
1735 |
1792 |
1.15e-7 |
SMART |
|
Pfam:MyTH4
|
1928 |
2029 |
8.3e-25 |
PFAM |
|
B41
|
2032 |
2235 |
6.99e-4 |
SMART |
|
low complexity region
|
2243 |
2253 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
C |
T |
8: 106,435,606 (GRCm39) |
T88M |
probably damaging |
Het |
| 9430038I01Rik |
A |
G |
7: 136,978,795 (GRCm39) |
|
probably benign |
Het |
| Adgra3 |
A |
C |
5: 50,118,834 (GRCm39) |
S905A |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,692,652 (GRCm39) |
Y1618H |
probably damaging |
Het |
| Anapc15-ps |
T |
C |
10: 95,509,176 (GRCm39) |
T26A |
probably benign |
Het |
| Ankrd13d |
T |
C |
19: 4,321,623 (GRCm39) |
K360E |
probably damaging |
Het |
| Anks1b |
T |
A |
10: 90,348,751 (GRCm39) |
|
probably null |
Het |
| Apob |
T |
C |
12: 8,057,602 (GRCm39) |
F2028S |
possibly damaging |
Het |
| Arap3 |
G |
A |
18: 38,108,636 (GRCm39) |
R1265W |
probably damaging |
Het |
| Arhgef37 |
A |
G |
18: 61,651,121 (GRCm39) |
Y135H |
probably damaging |
Het |
| Armh3 |
A |
C |
19: 45,963,691 (GRCm39) |
S42R |
probably benign |
Het |
| Atp1a1 |
T |
C |
3: 101,489,333 (GRCm39) |
T760A |
probably benign |
Het |
| Cdc42bpb |
T |
A |
12: 111,289,255 (GRCm39) |
M497L |
probably benign |
Het |
| Ces5a |
C |
T |
8: 94,240,859 (GRCm39) |
V413M |
probably damaging |
Het |
| Chd5 |
A |
T |
4: 152,470,263 (GRCm39) |
Y1903F |
probably damaging |
Het |
| Chd9 |
T |
A |
8: 91,737,422 (GRCm39) |
N1500K |
probably benign |
Het |
| Chmp7 |
G |
T |
14: 69,957,248 (GRCm39) |
D303E |
probably benign |
Het |
| Chrnb4 |
A |
T |
9: 54,942,102 (GRCm39) |
Y391N |
possibly damaging |
Het |
| Crtc1 |
T |
C |
8: 70,840,802 (GRCm39) |
T475A |
probably benign |
Het |
| Cyp2c69 |
A |
G |
19: 39,865,972 (GRCm39) |
I207T |
probably benign |
Het |
| Dcp1a |
A |
G |
14: 30,240,940 (GRCm39) |
E250G |
probably damaging |
Het |
| Ddx20 |
T |
C |
3: 105,586,398 (GRCm39) |
Q649R |
probably benign |
Het |
| Defb12 |
T |
A |
8: 19,162,754 (GRCm39) |
K59N |
probably damaging |
Het |
| Dpy19l3 |
A |
T |
7: 35,429,185 (GRCm39) |
I85N |
probably damaging |
Het |
| Duox2 |
C |
T |
2: 122,122,739 (GRCm39) |
|
probably null |
Het |
| Ebi3 |
T |
A |
17: 56,263,679 (GRCm39) |
Y197N |
probably damaging |
Het |
| Emc1 |
G |
A |
4: 139,102,823 (GRCm39) |
R994Q |
probably benign |
Het |
| Ercc6 |
G |
T |
14: 32,268,777 (GRCm39) |
M530I |
probably damaging |
Het |
| Evl |
T |
A |
12: 108,619,255 (GRCm39) |
D70E |
probably damaging |
Het |
| Fbln2 |
A |
G |
6: 91,242,757 (GRCm39) |
N819S |
probably damaging |
Het |
| Foxk2 |
A |
G |
11: 121,176,363 (GRCm39) |
I170V |
probably benign |
Het |
| Gfm1 |
T |
C |
3: 67,342,943 (GRCm39) |
V159A |
probably damaging |
Het |
| Gm10837 |
A |
G |
14: 122,728,177 (GRCm39) |
T18A |
unknown |
Het |
| Gm12887 |
A |
T |
4: 121,479,227 (GRCm39) |
V25E |
probably damaging |
Het |
| Hectd4 |
A |
G |
5: 121,435,243 (GRCm39) |
H985R |
possibly damaging |
Het |
| Hsfy2 |
A |
G |
1: 56,675,791 (GRCm39) |
Y249H |
possibly damaging |
Het |
| Hspg2 |
T |
C |
4: 137,272,878 (GRCm39) |
V2639A |
probably damaging |
Het |
| Igf2r |
A |
G |
17: 12,923,157 (GRCm39) |
|
probably null |
Het |
| Invs |
T |
A |
4: 48,422,035 (GRCm39) |
I889N |
probably damaging |
Het |
| Kcnq1 |
A |
T |
7: 142,736,857 (GRCm39) |
M209L |
probably benign |
Het |
| Klra7 |
A |
G |
6: 130,206,957 (GRCm39) |
I48T |
possibly damaging |
Het |
| Krt26 |
CTAGTA |
CTA |
11: 99,224,352 (GRCm39) |
|
probably benign |
Het |
| Lrif1 |
T |
A |
3: 106,640,127 (GRCm39) |
V404D |
probably damaging |
Het |
| Lrriq1 |
T |
A |
10: 103,063,034 (GRCm39) |
|
probably null |
Het |
| Lypd6 |
T |
A |
2: 50,078,774 (GRCm39) |
I90N |
possibly damaging |
Het |
| Mbp |
A |
G |
18: 82,602,247 (GRCm39) |
D174G |
probably damaging |
Het |
| Megf9 |
G |
T |
4: 70,453,022 (GRCm39) |
P13Q |
probably damaging |
Het |
| Nherf2 |
C |
T |
17: 24,860,693 (GRCm39) |
S150N |
possibly damaging |
Het |
| Nlrp6 |
T |
A |
7: 140,503,006 (GRCm39) |
C371S |
probably damaging |
Het |
| Nosip |
T |
A |
7: 44,726,733 (GRCm39) |
|
probably null |
Het |
| Nox3 |
G |
T |
17: 3,720,153 (GRCm39) |
P344H |
probably damaging |
Het |
| Nup210l |
T |
C |
3: 90,079,393 (GRCm39) |
V959A |
probably damaging |
Het |
| Or10d1 |
A |
G |
9: 39,484,031 (GRCm39) |
Y175H |
possibly damaging |
Het |
| Or2b2b |
C |
A |
13: 21,858,842 (GRCm39) |
V91L |
probably benign |
Het |
| Or2k2 |
T |
C |
4: 58,785,384 (GRCm39) |
I113V |
probably benign |
Het |
| Or5b119 |
A |
G |
19: 13,457,295 (GRCm39) |
I89T |
probably benign |
Het |
| Or5k8 |
T |
A |
16: 58,644,440 (GRCm39) |
I211F |
probably damaging |
Het |
| Osbpl3 |
A |
C |
6: 50,347,123 (GRCm39) |
S25A |
probably damaging |
Het |
| Otog |
G |
A |
7: 45,895,707 (GRCm39) |
C107Y |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,511,802 (GRCm39) |
R260C |
probably damaging |
Het |
| Pbrm1 |
A |
T |
14: 30,760,914 (GRCm39) |
I224F |
probably damaging |
Het |
| Pcdh1 |
T |
A |
18: 38,325,278 (GRCm39) |
|
probably null |
Het |
| Pcnx1 |
T |
C |
12: 82,027,709 (GRCm39) |
L1585P |
probably damaging |
Het |
| Pde4c |
C |
T |
8: 71,200,599 (GRCm39) |
H362Y |
probably damaging |
Het |
| Pdlim2 |
C |
T |
14: 70,402,228 (GRCm39) |
R296H |
probably damaging |
Het |
| Pgm1 |
A |
T |
4: 99,818,675 (GRCm39) |
Q90L |
probably damaging |
Het |
| Phlpp1 |
A |
G |
1: 106,271,235 (GRCm39) |
H814R |
probably benign |
Het |
| Pknox2 |
A |
T |
9: 36,866,127 (GRCm39) |
M5K |
possibly damaging |
Het |
| Pole |
G |
A |
5: 110,478,701 (GRCm39) |
|
probably null |
Het |
| Polr1b |
A |
G |
2: 128,944,886 (GRCm39) |
I61V |
probably benign |
Het |
| Prelp |
T |
C |
1: 133,842,495 (GRCm39) |
K217E |
probably damaging |
Het |
| Prkce |
C |
T |
17: 86,782,974 (GRCm39) |
Q202* |
probably null |
Het |
| Psmd2 |
T |
G |
16: 20,475,332 (GRCm39) |
M370R |
probably benign |
Het |
| Rimklb |
A |
T |
6: 122,440,968 (GRCm39) |
H68Q |
probably damaging |
Het |
| Rnasel |
A |
G |
1: 153,630,420 (GRCm39) |
D312G |
possibly damaging |
Het |
| Rxrg |
A |
T |
1: 167,426,321 (GRCm39) |
M1L |
probably benign |
Het |
| Scrn1 |
A |
G |
6: 54,499,826 (GRCm39) |
F220L |
possibly damaging |
Het |
| Scyl3 |
A |
G |
1: 163,778,244 (GRCm39) |
S461G |
probably benign |
Het |
| Serpina1c |
T |
A |
12: 103,861,282 (GRCm39) |
T411S |
probably benign |
Het |
| Serpinb6d |
C |
T |
13: 33,855,364 (GRCm39) |
P346L |
probably benign |
Het |
| Shld2 |
A |
G |
14: 33,989,760 (GRCm39) |
I382T |
probably benign |
Het |
| Spg21 |
G |
T |
9: 65,372,618 (GRCm39) |
V17F |
probably damaging |
Het |
| Spink5 |
A |
T |
18: 44,132,958 (GRCm39) |
M525L |
probably benign |
Het |
| Sun2 |
T |
C |
15: 79,621,764 (GRCm39) |
T155A |
probably benign |
Het |
| Tchh |
T |
A |
3: 93,354,087 (GRCm39) |
F1176I |
unknown |
Het |
| Tex15 |
T |
A |
8: 34,066,682 (GRCm39) |
D2037E |
probably benign |
Het |
| Tfdp2 |
T |
C |
9: 96,199,857 (GRCm39) |
C392R |
possibly damaging |
Het |
| Tmem30c |
T |
C |
16: 57,097,143 (GRCm39) |
N139S |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,021,568 (GRCm39) |
|
probably null |
Het |
| Trim66 |
T |
C |
7: 109,075,046 (GRCm39) |
E405G |
probably damaging |
Het |
| Trpc4 |
T |
A |
3: 54,187,415 (GRCm39) |
F456I |
probably benign |
Het |
| Tspo2 |
T |
C |
17: 48,755,818 (GRCm39) |
D108G |
possibly damaging |
Het |
| Tyk2 |
A |
T |
9: 21,032,850 (GRCm39) |
C304* |
probably null |
Het |
| Vgll4 |
A |
T |
6: 114,839,756 (GRCm39) |
S185T |
probably benign |
Het |
| Vmn2r94 |
A |
C |
17: 18,464,732 (GRCm39) |
S519R |
probably benign |
Het |
| Vmn2r96 |
T |
G |
17: 18,818,183 (GRCm39) |
S587A |
probably benign |
Het |
| Vps4b |
C |
A |
1: 106,706,712 (GRCm39) |
A287S |
possibly damaging |
Het |
| Yeats2 |
C |
T |
16: 20,048,314 (GRCm39) |
P1332S |
probably benign |
Het |
| Zfp462 |
T |
G |
4: 55,010,010 (GRCm39) |
S659A |
possibly damaging |
Het |
| Zfp507 |
C |
T |
7: 35,493,150 (GRCm39) |
R631Q |
probably damaging |
Het |
| Zfp764l1 |
A |
C |
7: 126,990,660 (GRCm39) |
D442E |
probably benign |
Het |
| Zswim5 |
G |
T |
4: 116,734,896 (GRCm39) |
E80D |
unknown |
Het |
|
| Other mutations in Myo15b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00556:Myo15b
|
APN |
11 |
115,782,742 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL01409:Myo15b
|
APN |
11 |
115,760,330 (GRCm39) |
nonsense |
probably null |
|
|
IGL01539:Myo15b
|
APN |
11 |
115,754,299 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01895:Myo15b
|
APN |
11 |
115,774,324 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02254:Myo15b
|
APN |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02343:Myo15b
|
APN |
11 |
115,764,226 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02349:Myo15b
|
APN |
11 |
115,753,931 (GRCm39) |
splice site |
probably benign |
|
|
IGL02368:Myo15b
|
APN |
11 |
115,767,828 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02576:Myo15b
|
APN |
11 |
115,780,879 (GRCm39) |
missense |
probably null |
0.97 |
|
IGL02650:Myo15b
|
APN |
11 |
115,777,337 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02661:Myo15b
|
APN |
11 |
115,774,895 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02716:Myo15b
|
APN |
11 |
115,774,535 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02733:Myo15b
|
APN |
11 |
115,775,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02951:Myo15b
|
APN |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03017:Myo15b
|
APN |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03029:Myo15b
|
APN |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
ANU74:Myo15b
|
UTSW |
11 |
115,769,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0092:Myo15b
|
UTSW |
11 |
115,753,812 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0255:Myo15b
|
UTSW |
11 |
115,777,109 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0325:Myo15b
|
UTSW |
11 |
115,775,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0614:Myo15b
|
UTSW |
11 |
115,773,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0652:Myo15b
|
UTSW |
11 |
115,755,468 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0711:Myo15b
|
UTSW |
11 |
115,774,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0815:Myo15b
|
UTSW |
11 |
115,757,162 (GRCm39) |
splice site |
probably benign |
|
|
R0961:Myo15b
|
UTSW |
11 |
115,773,280 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1066:Myo15b
|
UTSW |
11 |
115,770,577 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1221:Myo15b
|
UTSW |
11 |
115,777,546 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1240:Myo15b
|
UTSW |
11 |
115,771,327 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1275:Myo15b
|
UTSW |
11 |
115,774,318 (GRCm39) |
small deletion |
probably benign |
|
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1313:Myo15b
|
UTSW |
11 |
115,775,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1317:Myo15b
|
UTSW |
11 |
115,774,460 (GRCm39) |
missense |
probably null |
0.14 |
|
R1491:Myo15b
|
UTSW |
11 |
115,777,683 (GRCm39) |
splice site |
probably null |
|
|
R1552:Myo15b
|
UTSW |
11 |
115,757,461 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1731:Myo15b
|
UTSW |
11 |
115,782,386 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1800:Myo15b
|
UTSW |
11 |
115,771,335 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1894:Myo15b
|
UTSW |
11 |
115,777,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1917:Myo15b
|
UTSW |
11 |
115,773,080 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1934:Myo15b
|
UTSW |
11 |
115,754,310 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1939:Myo15b
|
UTSW |
11 |
115,778,529 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1945:Myo15b
|
UTSW |
11 |
115,769,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1986:Myo15b
|
UTSW |
11 |
115,773,701 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2130:Myo15b
|
UTSW |
11 |
115,762,469 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2138:Myo15b
|
UTSW |
11 |
115,774,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2176:Myo15b
|
UTSW |
11 |
115,757,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2415:Myo15b
|
UTSW |
11 |
115,770,390 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2483:Myo15b
|
UTSW |
11 |
115,755,565 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3620:Myo15b
|
UTSW |
11 |
115,762,013 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3716:Myo15b
|
UTSW |
11 |
115,754,239 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4013:Myo15b
|
UTSW |
11 |
115,762,282 (GRCm39) |
nonsense |
probably null |
|
|
R4021:Myo15b
|
UTSW |
11 |
115,764,331 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4119:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4120:Myo15b
|
UTSW |
11 |
115,764,318 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4499:Myo15b
|
UTSW |
11 |
115,781,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4653:Myo15b
|
UTSW |
11 |
115,770,813 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4655:Myo15b
|
UTSW |
11 |
115,781,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Myo15b
|
UTSW |
11 |
115,752,761 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R4702:Myo15b
|
UTSW |
11 |
115,774,834 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4777:Myo15b
|
UTSW |
11 |
115,770,478 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4833:Myo15b
|
UTSW |
11 |
115,778,428 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5083:Myo15b
|
UTSW |
11 |
115,757,482 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5121:Myo15b
|
UTSW |
11 |
115,776,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5146:Myo15b
|
UTSW |
11 |
115,782,024 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5535:Myo15b
|
UTSW |
11 |
115,772,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5647:Myo15b
|
UTSW |
11 |
115,762,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5849:Myo15b
|
UTSW |
11 |
115,772,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5882:Myo15b
|
UTSW |
11 |
115,760,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5956:Myo15b
|
UTSW |
11 |
115,764,583 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6273:Myo15b
|
UTSW |
11 |
115,753,625 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R6302:Myo15b
|
UTSW |
11 |
115,777,065 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6318:Myo15b
|
UTSW |
11 |
115,781,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6462:Myo15b
|
UTSW |
11 |
115,750,268 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6792:Myo15b
|
UTSW |
11 |
115,775,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6963:Myo15b
|
UTSW |
11 |
115,781,540 (GRCm39) |
splice site |
probably null |
|
|
R7015:Myo15b
|
UTSW |
11 |
115,762,670 (GRCm39) |
missense |
|
|
|
R7020:Myo15b
|
UTSW |
11 |
115,757,493 (GRCm39) |
nonsense |
probably null |
|
|
R7096:Myo15b
|
UTSW |
11 |
115,782,324 (GRCm39) |
splice site |
probably null |
|
|
R7219:Myo15b
|
UTSW |
11 |
115,767,921 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7400:Myo15b
|
UTSW |
11 |
115,750,939 (GRCm39) |
missense |
|
|
|
R7413:Myo15b
|
UTSW |
11 |
115,768,970 (GRCm39) |
missense |
|
|
|
R7483:Myo15b
|
UTSW |
11 |
115,749,570 (GRCm39) |
missense |
|
|
|
R7523:Myo15b
|
UTSW |
11 |
115,781,684 (GRCm39) |
missense |
unknown |
|
|
R7737:Myo15b
|
UTSW |
11 |
115,778,749 (GRCm39) |
missense |
unknown |
|
|
R7784:Myo15b
|
UTSW |
11 |
115,752,166 (GRCm39) |
missense |
|
|
|
R7842:Myo15b
|
UTSW |
11 |
115,762,321 (GRCm39) |
missense |
|
|
|
R7921:Myo15b
|
UTSW |
11 |
115,778,004 (GRCm39) |
nonsense |
probably null |
|
|
R8065:Myo15b
|
UTSW |
11 |
115,778,769 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8183:Myo15b
|
UTSW |
11 |
115,773,843 (GRCm39) |
splice site |
probably null |
|
|
R8193:Myo15b
|
UTSW |
11 |
115,775,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8237:Myo15b
|
UTSW |
11 |
115,767,827 (GRCm39) |
missense |
|
|
|
R8430:Myo15b
|
UTSW |
11 |
115,773,049 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8482:Myo15b
|
UTSW |
11 |
115,774,083 (GRCm39) |
nonsense |
probably null |
|
|
R8515:Myo15b
|
UTSW |
11 |
115,749,610 (GRCm39) |
missense |
|
|
|
R8798:Myo15b
|
UTSW |
11 |
115,754,232 (GRCm39) |
missense |
|
|
|
R8937:Myo15b
|
UTSW |
11 |
115,773,127 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8975:Myo15b
|
UTSW |
11 |
115,781,780 (GRCm39) |
missense |
unknown |
|
|
R9045:Myo15b
|
UTSW |
11 |
115,783,178 (GRCm39) |
makesense |
probably null |
|
|
R9117:Myo15b
|
UTSW |
11 |
115,778,743 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9185:Myo15b
|
UTSW |
11 |
115,771,255 (GRCm39) |
missense |
unknown |
|
|
R9226:Myo15b
|
UTSW |
11 |
115,750,924 (GRCm39) |
missense |
|
|
|
R9302:Myo15b
|
UTSW |
11 |
115,776,238 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9318:Myo15b
|
UTSW |
11 |
115,775,965 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9336:Myo15b
|
UTSW |
11 |
115,771,064 (GRCm39) |
missense |
|
|
|
R9337:Myo15b
|
UTSW |
11 |
115,749,861 (GRCm39) |
missense |
|
|
|
R9338:Myo15b
|
UTSW |
11 |
115,762,238 (GRCm39) |
missense |
|
|
|
R9498:Myo15b
|
UTSW |
11 |
115,770,784 (GRCm39) |
missense |
|
|
|
R9500:Myo15b
|
UTSW |
11 |
115,777,466 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9602:Myo15b
|
UTSW |
11 |
115,769,269 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9642:Myo15b
|
UTSW |
11 |
115,772,335 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
X0020:Myo15b
|
UTSW |
11 |
115,762,625 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,778,751 (GRCm39) |
missense |
unknown |
|
|
Z1176:Myo15b
|
UTSW |
11 |
115,774,278 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCGGTCTTCAGGAAGGAAC -3'
(R):5'- GGCTCAGTGGTTAAGAGAGC -3'
Sequencing Primer
(F):5'- TCTTCAGGAAGGAACGGGGTG -3'
(R):5'- TAAGACACCTGCTGCTGAGTCTG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation