Incidental Mutation 'R1846:N4bp2'
| ID |
207718 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
N4bp2
|
| Ensembl Gene |
ENSMUSG00000037795 |
| Gene Name |
NEDD4 binding protein 2 |
| Synonyms |
B3bp, LOC333789, LOC386488 |
| MMRRC Submission |
039871-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.140)
|
| Stock # |
R1846 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
65763521-65830108 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 65808519 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Phenylalanine to Leucine
at position 1304
(F1304L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144278
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087264]
[ENSMUST00000201489]
[ENSMUST00000201615]
|
| AlphaFold |
F8VQG7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000087264
AA Change: F1304L
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000084519
Gene: ENSMUSG00000037795
AA Change: F1304L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.1e-15 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113738
AA Change: F1304L
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000109367
Gene: ENSMUSG00000037795
AA Change: F1304L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200843
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201489
AA Change: F1304L
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000143807
Gene: ENSMUSG00000037795
AA Change: F1304L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201615
AA Change: F1304L
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000144278
Gene: ENSMUSG00000037795
AA Change: F1304L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.2e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
8e-10 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202411
|
| Meta Mutation Damage Score |
0.2094 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.6%
|
| Validation Efficiency |
99% (75/76) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
|
| Allele List at MGI |
All alleles(9) : Targeted, other(2) Gene trapped(7)
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700011H14Rik |
G |
T |
14: 49,235,963 (GRCm38) |
L102I |
probably damaging |
Het |
| 2900092C05Rik |
G |
A |
7: 12,512,882 (GRCm38) |
R63Q |
probably benign |
Het |
| Adamts20 |
A |
T |
15: 94,345,990 (GRCm38) |
C619S |
probably damaging |
Het |
| Alx1 |
T |
C |
10: 103,025,304 (GRCm38) |
D121G |
possibly damaging |
Het |
| Anks3 |
A |
C |
16: 4,953,884 (GRCm38) |
M215R |
probably benign |
Het |
| Anxa4 |
T |
A |
6: 86,741,911 (GRCm38) |
|
probably null |
Het |
| Arhgef25 |
A |
G |
10: 127,185,864 (GRCm38) |
V222A |
probably damaging |
Het |
| Bglap2 |
A |
G |
3: 88,378,625 (GRCm38) |
|
probably benign |
Het |
| Cars2 |
A |
G |
8: 11,514,674 (GRCm38) |
V22A |
probably benign |
Het |
| Cenpe |
T |
A |
3: 135,239,845 (GRCm38) |
I1040N |
probably damaging |
Het |
| Cep170 |
C |
T |
1: 176,755,769 (GRCm38) |
D1015N |
probably damaging |
Het |
| Chia1 |
T |
A |
3: 106,130,865 (GRCm38) |
I359N |
probably damaging |
Het |
| Crot |
A |
T |
5: 8,988,248 (GRCm38) |
V93E |
probably benign |
Het |
| Dab1 |
C |
T |
4: 104,731,751 (GRCm38) |
A524V |
probably benign |
Het |
| Dnmbp |
T |
C |
19: 43,902,747 (GRCm38) |
I194V |
probably damaging |
Het |
| Dock4 |
T |
A |
12: 40,733,268 (GRCm38) |
C734S |
probably benign |
Het |
| Eif4e3 |
T |
C |
6: 99,640,701 (GRCm38) |
S70G |
probably benign |
Het |
| Entpd3 |
G |
A |
9: 120,558,375 (GRCm38) |
D213N |
probably benign |
Het |
| Ern2 |
T |
G |
7: 122,176,536 (GRCm38) |
Y445S |
probably benign |
Het |
| Fasn |
A |
G |
11: 120,813,307 (GRCm38) |
S1429P |
probably benign |
Het |
| Fat4 |
A |
G |
3: 38,982,383 (GRCm38) |
I3395V |
probably benign |
Het |
| Fbln2 |
C |
A |
6: 91,256,417 (GRCm38) |
Q628K |
possibly damaging |
Het |
| Fbxo28 |
T |
C |
1: 182,326,280 (GRCm38) |
N164D |
probably benign |
Het |
| Fez1 |
T |
C |
9: 36,867,767 (GRCm38) |
S247P |
probably damaging |
Het |
| Gars |
A |
G |
6: 55,063,168 (GRCm38) |
D360G |
probably benign |
Het |
| Gcfc2 |
A |
T |
6: 81,956,892 (GRCm38) |
Q710L |
probably damaging |
Het |
| Ggt5 |
A |
G |
10: 75,610,542 (GRCm38) |
|
probably null |
Het |
| Glp1r |
A |
G |
17: 30,929,935 (GRCm38) |
|
probably null |
Het |
| Hspa14 |
T |
C |
2: 3,491,660 (GRCm38) |
D356G |
possibly damaging |
Het |
| Htt |
T |
A |
5: 34,848,944 (GRCm38) |
I1399N |
probably damaging |
Het |
| Kmt2e |
G |
A |
5: 23,499,486 (GRCm38) |
|
probably benign |
Het |
| Krt36 |
C |
A |
11: 100,105,548 (GRCm38) |
G17C |
probably damaging |
Het |
| Lama2 |
T |
C |
10: 27,212,096 (GRCm38) |
E895G |
probably damaging |
Het |
| Lamb2 |
G |
A |
9: 108,487,387 (GRCm38) |
R1142H |
probably benign |
Het |
| Lhcgr |
C |
T |
17: 88,765,147 (GRCm38) |
|
probably null |
Het |
| Lpin2 |
A |
G |
17: 71,225,069 (GRCm38) |
T140A |
probably benign |
Het |
| Metap1 |
A |
G |
3: 138,480,682 (GRCm38) |
|
probably benign |
Het |
| Mpeg1 |
T |
C |
19: 12,463,122 (GRCm38) |
V648A |
probably benign |
Het |
| Mroh2a |
A |
G |
1: 88,258,664 (GRCm38) |
S64G |
probably benign |
Het |
| Muc4 |
T |
A |
16: 32,752,369 (GRCm38) |
I749N |
probably benign |
Het |
| Nup85 |
A |
G |
11: 115,568,413 (GRCm38) |
E114G |
probably benign |
Het |
| Olfr1258 |
A |
G |
2: 89,930,666 (GRCm38) |
T286A |
possibly damaging |
Het |
| Olfr1415 |
A |
T |
1: 92,491,100 (GRCm38) |
Y218* |
probably null |
Het |
| Olfr448 |
A |
G |
6: 42,897,320 (GRCm38) |
S290G |
probably damaging |
Het |
| Pafah2 |
GCCCC |
GCCCCC |
4: 134,425,541 (GRCm38) |
|
probably null |
Het |
| Parp2 |
T |
A |
14: 50,815,386 (GRCm38) |
C145* |
probably null |
Het |
| Plpp6 |
T |
C |
19: 28,964,280 (GRCm38) |
S94P |
probably benign |
Het |
| Polr1a |
T |
C |
6: 71,976,188 (GRCm38) |
I1580T |
probably damaging |
Het |
| Polrmt |
A |
T |
10: 79,738,209 (GRCm38) |
V860E |
probably damaging |
Het |
| Ppp1r17 |
A |
G |
6: 56,022,427 (GRCm38) |
E15G |
possibly damaging |
Het |
| Prl7b1 |
A |
T |
13: 27,602,848 (GRCm38) |
W133R |
probably damaging |
Het |
| Ptk7 |
A |
G |
17: 46,576,490 (GRCm38) |
|
probably null |
Het |
| Rad23b |
C |
T |
4: 55,383,637 (GRCm38) |
Q290* |
probably null |
Het |
| Rorb |
C |
T |
19: 18,955,081 (GRCm38) |
E369K |
probably damaging |
Het |
| Rusc1 |
T |
C |
3: 89,092,145 (GRCm38) |
D110G |
probably damaging |
Het |
| Smg7 |
A |
G |
1: 152,848,850 (GRCm38) |
S527P |
probably damaging |
Het |
| Ssbp2 |
C |
T |
13: 91,664,149 (GRCm38) |
P105L |
probably damaging |
Het |
| Stt3a |
C |
T |
9: 36,763,385 (GRCm38) |
R34H |
probably damaging |
Het |
| Sufu |
T |
A |
19: 46,450,947 (GRCm38) |
I202N |
possibly damaging |
Het |
| Thsd7b |
G |
A |
1: 129,613,256 (GRCm38) |
R289Q |
probably damaging |
Het |
| Tph1 |
A |
T |
7: 46,660,439 (GRCm38) |
S130T |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,945,686 (GRCm38) |
S1671P |
probably damaging |
Het |
| Usp4 |
A |
G |
9: 108,372,736 (GRCm38) |
I441V |
probably benign |
Het |
| Vmn1r8 |
A |
G |
6: 57,036,428 (GRCm38) |
N155D |
probably benign |
Het |
| Vmn2r115 |
A |
C |
17: 23,359,383 (GRCm38) |
K610T |
probably damaging |
Het |
| Vmn2r62 |
G |
A |
7: 42,789,122 (GRCm38) |
P97S |
probably damaging |
Het |
| Zbtb40 |
T |
C |
4: 137,007,839 (GRCm38) |
D297G |
probably benign |
Het |
| Zfp174 |
C |
A |
16: 3,854,735 (GRCm38) |
Q383K |
probably benign |
Het |
| Zfp318 |
T |
A |
17: 46,413,666 (GRCm38) |
D2198E |
probably benign |
Het |
| Zfp628 |
C |
T |
7: 4,920,867 (GRCm38) |
P696L |
possibly damaging |
Het |
| Zgrf1 |
T |
A |
3: 127,615,463 (GRCm38) |
N1695K |
probably damaging |
Het |
|
| Other mutations in N4bp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:N4bp2
|
APN |
5 |
65,807,524 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL01503:N4bp2
|
APN |
5 |
65,803,547 (GRCm38) |
nonsense |
probably null |
0.00 |
|
IGL01621:N4bp2
|
APN |
5 |
65,790,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02109:N4bp2
|
APN |
5 |
65,798,134 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02286:N4bp2
|
APN |
5 |
65,803,552 (GRCm38) |
missense |
probably damaging |
1.00 |
|
1mM(1):N4bp2
|
UTSW |
5 |
65,807,677 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03046:N4bp2
|
UTSW |
5 |
65,790,960 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0164:N4bp2
|
UTSW |
5 |
65,803,573 (GRCm38) |
splice site |
probably benign |
|
|
R0285:N4bp2
|
UTSW |
5 |
65,806,559 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0366:N4bp2
|
UTSW |
5 |
65,806,396 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R0548:N4bp2
|
UTSW |
5 |
65,808,153 (GRCm38) |
missense |
probably benign |
0.39 |
|
R0551:N4bp2
|
UTSW |
5 |
65,820,341 (GRCm38) |
splice site |
probably null |
|
|
R0671:N4bp2
|
UTSW |
5 |
65,807,437 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1136:N4bp2
|
UTSW |
5 |
65,808,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1515:N4bp2
|
UTSW |
5 |
65,790,498 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1597:N4bp2
|
UTSW |
5 |
65,807,140 (GRCm38) |
missense |
probably benign |
0.45 |
|
R1628:N4bp2
|
UTSW |
5 |
65,803,572 (GRCm38) |
splice site |
probably null |
|
|
R1722:N4bp2
|
UTSW |
5 |
65,806,882 (GRCm38) |
missense |
probably benign |
0.08 |
|
R1735:N4bp2
|
UTSW |
5 |
65,808,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1745:N4bp2
|
UTSW |
5 |
65,790,822 (GRCm38) |
missense |
probably benign |
0.12 |
|
R1759:N4bp2
|
UTSW |
5 |
65,826,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1799:N4bp2
|
UTSW |
5 |
65,806,825 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R1872:N4bp2
|
UTSW |
5 |
65,794,518 (GRCm38) |
splice site |
probably benign |
|
|
R2042:N4bp2
|
UTSW |
5 |
65,826,621 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2082:N4bp2
|
UTSW |
5 |
65,807,565 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2101:N4bp2
|
UTSW |
5 |
65,790,881 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2147:N4bp2
|
UTSW |
5 |
65,809,200 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2251:N4bp2
|
UTSW |
5 |
65,806,728 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2507:N4bp2
|
UTSW |
5 |
65,790,061 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2508:N4bp2
|
UTSW |
5 |
65,790,061 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2919:N4bp2
|
UTSW |
5 |
65,807,098 (GRCm38) |
missense |
probably benign |
0.22 |
|
R3086:N4bp2
|
UTSW |
5 |
65,791,053 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4092:N4bp2
|
UTSW |
5 |
65,790,456 (GRCm38) |
missense |
probably benign |
0.02 |
|
R4177:N4bp2
|
UTSW |
5 |
65,798,170 (GRCm38) |
splice site |
probably null |
|
|
R4718:N4bp2
|
UTSW |
5 |
65,803,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4859:N4bp2
|
UTSW |
5 |
65,825,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4863:N4bp2
|
UTSW |
5 |
65,808,130 (GRCm38) |
missense |
probably benign |
0.22 |
|
R4915:N4bp2
|
UTSW |
5 |
65,803,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4949:N4bp2
|
UTSW |
5 |
65,821,799 (GRCm38) |
splice site |
probably null |
|
|
R4978:N4bp2
|
UTSW |
5 |
65,790,240 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5029:N4bp2
|
UTSW |
5 |
65,814,780 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5079:N4bp2
|
UTSW |
5 |
65,811,977 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5097:N4bp2
|
UTSW |
5 |
65,817,218 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5158:N4bp2
|
UTSW |
5 |
65,808,462 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5228:N4bp2
|
UTSW |
5 |
65,807,518 (GRCm38) |
missense |
probably benign |
|
|
R5322:N4bp2
|
UTSW |
5 |
65,790,457 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
R5554:N4bp2
|
UTSW |
5 |
65,808,114 (GRCm38) |
missense |
probably benign |
0.44 |
|
R5731:N4bp2
|
UTSW |
5 |
65,809,157 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5840:N4bp2
|
UTSW |
5 |
65,808,094 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6393:N4bp2
|
UTSW |
5 |
65,791,001 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R6767:N4bp2
|
UTSW |
5 |
65,817,187 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7103:N4bp2
|
UTSW |
5 |
65,806,846 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7112:N4bp2
|
UTSW |
5 |
65,790,707 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
R7171:N4bp2
|
UTSW |
5 |
65,808,022 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7177:N4bp2
|
UTSW |
5 |
65,807,548 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7240:N4bp2
|
UTSW |
5 |
65,794,545 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7353:N4bp2
|
UTSW |
5 |
65,806,371 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7450:N4bp2
|
UTSW |
5 |
65,825,300 (GRCm38) |
nonsense |
probably null |
|
|
R7560:N4bp2
|
UTSW |
5 |
65,791,115 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7698:N4bp2
|
UTSW |
5 |
65,808,157 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7743:N4bp2
|
UTSW |
5 |
65,808,459 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7871:N4bp2
|
UTSW |
5 |
65,807,103 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7981:N4bp2
|
UTSW |
5 |
65,812,142 (GRCm38) |
missense |
probably benign |
0.41 |
|
R8065:N4bp2
|
UTSW |
5 |
65,807,296 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8067:N4bp2
|
UTSW |
5 |
65,807,296 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8164:N4bp2
|
UTSW |
5 |
65,809,223 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8166:N4bp2
|
UTSW |
5 |
65,820,312 (GRCm38) |
missense |
probably benign |
0.39 |
|
R8331:N4bp2
|
UTSW |
5 |
65,807,600 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8559:N4bp2
|
UTSW |
5 |
65,825,285 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R8806:N4bp2
|
UTSW |
5 |
65,808,208 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R9287:N4bp2
|
UTSW |
5 |
65,803,512 (GRCm38) |
missense |
probably benign |
0.38 |
|
R9369:N4bp2
|
UTSW |
5 |
65,806,916 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9460:N4bp2
|
UTSW |
5 |
65,806,543 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9462:N4bp2
|
UTSW |
5 |
65,790,555 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9605:N4bp2
|
UTSW |
5 |
65,806,536 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9641:N4bp2
|
UTSW |
5 |
65,790,692 (GRCm38) |
missense |
probably benign |
0.15 |
|
Z1177:N4bp2
|
UTSW |
5 |
65,807,637 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTTACTGGCTCTTTGGAAGTAAAG -3'
(R):5'- TCCAGGAAAACTTGCAACATG -3'
Sequencing Primer
(F):5'- TGTGAAATTTGCAAACATGGAAG -3'
(R):5'- CCAGGAAAACTTGCAACATGTTCATG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation