Mutagenetix > Incidental Mutation

Incidental Mutation 'R1848:Vps13c'

207915

Institutional Source

Beutler Lab

Gene Symbol

Vps13c

Ensembl Gene

ENSMUSG00000035284

Gene Name

vacuolar protein sorting 13C

Synonyms

C230055H22Rik

MMRRC Submission

039873-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1848 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

67747678-67902920 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 67843622 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Alanine at position 1968 (T1968A)

Ref Sequence

ENSEMBL: ENSMUSP00000077040 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077879]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000077879
AA Change: T1968A

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000077040
Gene: ENSMUSG00000035284
AA Change: T1968A

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	3	117	1.3e-39	PFAM
low complexity region	151	165	N/A	INTRINSIC
Pfam:VPS13	182	414	7.9e-70	PFAM
coiled coil region	422	443	N/A	INTRINSIC
low complexity region	479	490	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	611	832	7.8e-71	PFAM
low complexity region	867	885	N/A	INTRINSIC
low complexity region	1020	1036	N/A	INTRINSIC
low complexity region	1112	1123	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1172	1369	2.1e-14	PFAM
low complexity region	1552	1573	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1685	1883	2.8e-13	PFAM
Blast:INB	2128	2403	2e-48	BLAST
Pfam:SHR-BD	2759	3013	9.9e-32	PFAM
Pfam:VPS13_C	3317	3495	5.7e-65	PFAM
Pfam:ATG_C	3498	3588	7.9e-12	PFAM

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.2%
20x: 92.2%

Validation Efficiency

98% (120/123)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]

Allele List at MGI

All alleles(13) : Targeted, other(2) Gene trapped(11)

Other mutations in this stock

Total: 120 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933402J07Rik	C	A	8: 88,295,121 (GRCm39)	Y86*	probably null	Het
Aadac	A	G	3: 59,947,118 (GRCm39)	E272G	probably damaging	Het
Abcc8	A	T	7: 45,816,326 (GRCm39)	D271E	probably benign	Het
Acan	T	C	7: 78,748,783 (GRCm39)	F1185L	probably benign	Het
Adam1a	A	T	5: 121,657,683 (GRCm39)	C537S	probably damaging	Het
Ago2	A	G	15: 72,995,814 (GRCm39)	V395A	probably benign	Het
Alox15	A	G	11: 70,241,578 (GRCm39)	V101A	probably damaging	Het
Ankra2	T	C	13: 98,407,632 (GRCm39)	I194T	probably damaging	Het
Apobec4	C	A	1: 152,631,981 (GRCm39)	P3H	probably damaging	Het
Arid3b	G	T	9: 57,703,960 (GRCm39)	Y329*	probably null	Het
Atm	A	T	9: 53,379,312 (GRCm39)	S1993T	probably benign	Het
Bpgm	T	G	6: 34,464,669 (GRCm39)	S129A	probably benign	Het
Brat1	A	G	5: 140,704,264 (GRCm39)	D839G	possibly damaging	Het
Ccdc15	A	T	9: 37,253,866 (GRCm39)	S128T	probably benign	Het
Cd300lg	A	T	11: 101,937,032 (GRCm39)		probably benign	Het
Cdc34b	C	A	11: 94,633,303 (GRCm39)	Q168K	probably damaging	Het
Celsr2	A	T	3: 108,308,626 (GRCm39)	V1767E	probably benign	Het
Cep350	T	C	1: 155,829,397 (GRCm39)	D169G	probably benign	Het
Col7a1	A	T	9: 108,798,633 (GRCm39)	D1762V	possibly damaging	Het
Coro7	A	G	16: 4,448,298 (GRCm39)	L724P	probably damaging	Het
Crb1	T	A	1: 139,164,750 (GRCm39)	I1125F	probably damaging	Het
Ctif	T	A	18: 75,653,012 (GRCm39)	D415V	probably damaging	Het
Dab1	C	T	4: 104,588,948 (GRCm39)	A524V	probably benign	Het
Dhrs2	A	G	14: 55,478,298 (GRCm39)	D237G	probably benign	Het
Dhx9	T	C	1: 153,341,499 (GRCm39)	Q582R	probably damaging	Het
Dnajc1	C	T	2: 18,224,524 (GRCm39)	R443Q	probably damaging	Het
Dnm2	C	T	9: 21,416,977 (GRCm39)	R837W	possibly damaging	Het
Dpf2	C	A	19: 5,956,643 (GRCm39)	Q70H	probably damaging	Het
Dqx1	T	A	6: 83,043,088 (GRCm39)	D608E	probably damaging	Het
Dync2h1	T	A	9: 7,049,166 (GRCm39)	T3245S	probably benign	Het
Ect2l	A	G	10: 18,075,781 (GRCm39)	L35P	probably damaging	Het
Efcab5	A	T	11: 76,994,132 (GRCm39)	L1285Q	probably damaging	Het
Eif4g1	G	C	16: 20,500,617 (GRCm39)	R697P	probably damaging	Het
Emsy	T	A	7: 98,250,028 (GRCm39)	E753V	probably damaging	Het
Entpd3	A	G	9: 120,387,485 (GRCm39)	I227M	probably damaging	Het
Epn1	T	A	7: 5,092,997 (GRCm39)	V103E	probably damaging	Het
Esrra	T	C	19: 6,889,378 (GRCm39)	D337G	probably benign	Het
Fam83e	A	T	7: 45,378,193 (GRCm39)	K406*	probably null	Het
Fam83e	A	T	7: 45,378,194 (GRCm39)	K406M	possibly damaging	Het
Fat2	A	G	11: 55,202,384 (GRCm39)	I230T	probably damaging	Het
Fbxl16	A	G	17: 26,035,420 (GRCm39)	I6V	probably benign	Het
Fgf23	T	C	6: 127,050,156 (GRCm39)	I55T	probably damaging	Het
Fibcd1	T	A	2: 31,711,561 (GRCm39)	D288V	probably damaging	Het
Flnb	T	C	14: 7,892,113 (GRCm38)	I594T	probably damaging	Het
Gabbr2	T	C	4: 46,739,823 (GRCm39)	E449G	probably benign	Het
Gbf1	T	G	19: 46,260,476 (GRCm39)	S1130A	possibly damaging	Het
Gipc3	T	C	10: 81,177,099 (GRCm39)	E157G	probably damaging	Het
Glra3	G	T	8: 56,393,942 (GRCm39)	A18S	probably benign	Het
Gm6625	A	C	8: 89,873,462 (GRCm39)		noncoding transcript	Het
Gpx4	A	G	10: 79,891,870 (GRCm39)		probably benign	Het
Grb10	A	G	11: 11,896,029 (GRCm39)	F264L	possibly damaging	Het
Grik3	T	C	4: 125,587,931 (GRCm39)	Y684H	probably damaging	Het
Gstp1	C	T	19: 4,086,795 (GRCm39)		probably benign	Het
H2bc27	A	T	11: 58,839,928 (GRCm39)	I55F	possibly damaging	Het
Haus8	G	A	8: 71,708,767 (GRCm39)		probably benign	Het
Hip1	G	A	5: 135,463,995 (GRCm39)		probably null	Het
Hspbap1	T	A	16: 35,639,134 (GRCm39)		probably null	Het
Htr2b	T	A	1: 86,027,151 (GRCm39)	I452F	possibly damaging	Het
Hydin	T	A	8: 111,296,440 (GRCm39)	H3656Q	probably benign	Het
Klb	T	A	5: 65,506,180 (GRCm39)	D142E	probably benign	Het
Lamb3	A	T	1: 193,016,924 (GRCm39)	T777S	possibly damaging	Het
Lins1	C	A	7: 66,364,070 (GRCm39)	T650K	probably damaging	Het
Loxhd1	A	G	18: 77,369,667 (GRCm39)	K5R	possibly damaging	Het
Lpp	G	A	16: 24,580,405 (GRCm39)	M40I	probably damaging	Het
Mia2	A	T	12: 59,217,037 (GRCm39)		probably benign	Het
Miip	A	C	4: 147,947,549 (GRCm39)	F204V	probably damaging	Het
Mmp21	T	C	7: 133,278,882 (GRCm39)	R323G	probably benign	Het
Mta3	T	A	17: 84,062,980 (GRCm39)		probably benign	Het
Myh1	A	G	11: 67,104,456 (GRCm39)	K1004R	probably benign	Het
Myh14	T	A	7: 44,281,853 (GRCm39)	I810F	probably damaging	Het
Nbas	A	C	12: 13,463,598 (GRCm39)	D1295A	probably damaging	Het
Niban3	T	C	8: 72,056,413 (GRCm39)	M371T	possibly damaging	Het
Npr2	T	G	4: 43,632,384 (GRCm39)	V67G	probably benign	Het
Oas1f	C	A	5: 120,993,492 (GRCm39)	Q235K	probably damaging	Het
Or12d17	T	A	17: 37,777,938 (GRCm39)	S280R	probably damaging	Het
Or13a27	T	A	7: 139,925,900 (GRCm39)	M1L	probably benign	Het
Or1p1	G	T	11: 74,180,039 (GRCm39)	C189F	probably damaging	Het
Or52ae9	T	C	7: 103,390,381 (GRCm39)	N22S	probably benign	Het
Or7e166	C	T	9: 19,624,386 (GRCm39)	H88Y	probably benign	Het
Pafah2	GCCCC	GCCCCC	4: 134,152,852 (GRCm39)		probably null	Het
Pde1b	A	G	15: 103,433,767 (GRCm39)		probably null	Het
Pdilt	T	C	7: 119,088,607 (GRCm39)	T465A	probably benign	Het
Plxnd1	T	C	6: 115,943,507 (GRCm39)	H1233R	probably damaging	Het
Ppm1b	T	A	17: 85,301,552 (GRCm39)	M144K	probably benign	Het
Prkdc	T	C	16: 15,625,922 (GRCm39)	L3316S	probably benign	Het
Prm2	T	A	16: 10,609,455 (GRCm39)		probably benign	Het
Prmt7	T	C	8: 106,963,640 (GRCm39)	V240A	probably benign	Het
Prx	C	A	7: 27,218,313 (GRCm39)	A938E	possibly damaging	Het
Rbm7	A	G	9: 48,402,194 (GRCm39)	V131A	probably benign	Het
Ric1	T	A	19: 29,578,213 (GRCm39)		probably null	Het
Rnf150	A	T	8: 83,590,639 (GRCm39)	M1L	possibly damaging	Het
Rnf20	C	T	4: 49,644,628 (GRCm39)	R298W	probably damaging	Het
Rp1	T	A	1: 4,417,455 (GRCm39)	Y1219F	possibly damaging	Het
Scn7a	A	G	2: 66,514,357 (GRCm39)		probably null	Het
Sdad1	A	G	5: 92,440,510 (GRCm39)		probably null	Het
Septin9	T	C	11: 117,243,909 (GRCm39)		probably benign	Het
Serinc3	T	C	2: 163,487,409 (GRCm39)		probably benign	Het
Shc3	C	T	13: 51,615,424 (GRCm39)	G178R	probably damaging	Het
Slc4a10	A	T	2: 62,146,950 (GRCm39)	K1090M	probably damaging	Het
Slco1a1	T	C	6: 141,868,837 (GRCm39)	I376V	probably benign	Het
Slmap	A	T	14: 26,143,729 (GRCm39)	F719L	probably benign	Het
Smgc	A	G	15: 91,743,956 (GRCm39)	N573D	possibly damaging	Het
Spx	G	A	6: 142,359,805 (GRCm39)		probably null	Het
Srrt	C	G	5: 137,295,207 (GRCm39)	E308Q	probably damaging	Het
Tas2r130	T	A	6: 131,607,560 (GRCm39)	R78S	probably benign	Het
Tchhl1	A	G	3: 93,378,408 (GRCm39)	R371G	probably damaging	Het
Teddm2	C	T	1: 153,726,194 (GRCm39)	A174T	probably benign	Het
Tktl2	G	A	8: 66,964,999 (GRCm39)	V186M	probably damaging	Het
Trim33	T	C	3: 103,231,956 (GRCm39)		probably benign	Het
Tspan31	A	G	10: 126,905,327 (GRCm39)	V40A	probably damaging	Het
Uevld	A	G	7: 46,594,975 (GRCm39)		probably benign	Het
Vcl	G	T	14: 21,059,063 (GRCm39)	A560S	probably benign	Het
Vmn2r24	T	A	6: 123,793,183 (GRCm39)	C837S	probably damaging	Het
Vmn2r57	C	T	7: 41,077,531 (GRCm39)	V212M	probably damaging	Het
Vtn	A	G	11: 78,391,393 (GRCm39)	R269G	probably damaging	Het
Wdcp	G	A	12: 4,900,245 (GRCm39)	V34I	possibly damaging	Het
Zc3h14	A	G	12: 98,719,091 (GRCm39)	D152G	possibly damaging	Het
Zfp189	C	T	4: 49,529,266 (GRCm39)	P123L	probably benign	Het
Zfp318	T	C	17: 46,716,981 (GRCm39)	S1038P	possibly damaging	Het
Zfp873	A	G	10: 81,896,406 (GRCm39)	D416G	probably benign	Het

Other mutations in Vps13c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Vps13c	APN	9	67,853,281 (GRCm39)	missense	probably benign	0.20
IGL00336:Vps13c	APN	9	67,853,224 (GRCm39)	missense	probably benign	0.01
IGL00418:Vps13c	APN	9	67,783,544 (GRCm39)	missense	probably damaging	1.00
IGL00481:Vps13c	APN	9	67,768,147 (GRCm39)	missense	probably damaging	1.00
IGL00491:Vps13c	APN	9	67,800,418 (GRCm39)	missense	probably damaging	1.00
IGL00558:Vps13c	APN	9	67,845,139 (GRCm39)	missense	possibly damaging	0.52
IGL00811:Vps13c	APN	9	67,855,463 (GRCm39)	missense	probably damaging	0.99
IGL01011:Vps13c	APN	9	67,834,237 (GRCm39)	missense	probably damaging	0.98
IGL01094:Vps13c	APN	9	67,793,566 (GRCm39)	missense	probably damaging	1.00
IGL01330:Vps13c	APN	9	67,871,390 (GRCm39)	missense	probably damaging	1.00
IGL01402:Vps13c	APN	9	67,820,486 (GRCm39)	critical splice acceptor site	probably null
IGL01404:Vps13c	APN	9	67,820,486 (GRCm39)	critical splice acceptor site	probably null
IGL01470:Vps13c	APN	9	67,820,209 (GRCm39)	splice site	probably benign
IGL01615:Vps13c	APN	9	67,863,063 (GRCm39)	missense	probably benign	0.01
IGL01694:Vps13c	APN	9	67,802,631 (GRCm39)	missense	probably damaging	1.00
IGL01752:Vps13c	APN	9	67,855,510 (GRCm39)	missense	probably damaging	1.00
IGL01810:Vps13c	APN	9	67,863,062 (GRCm39)	missense	probably benign
IGL01954:Vps13c	APN	9	67,876,580 (GRCm39)	missense	probably damaging	0.98
IGL01978:Vps13c	APN	9	67,837,925 (GRCm39)	missense	probably benign	0.03
IGL01998:Vps13c	APN	9	67,862,350 (GRCm39)	splice site	probably null
IGL02201:Vps13c	APN	9	67,874,418 (GRCm39)	missense	probably damaging	1.00
IGL02205:Vps13c	APN	9	67,790,736 (GRCm39)	missense	probably damaging	1.00
IGL02303:Vps13c	APN	9	67,852,763 (GRCm39)	splice site	probably benign
IGL02322:Vps13c	APN	9	67,845,183 (GRCm39)	missense	probably benign	0.02
IGL02456:Vps13c	APN	9	67,860,258 (GRCm39)	missense	probably damaging	1.00
IGL02474:Vps13c	APN	9	67,845,158 (GRCm39)	missense	probably benign	0.00
IGL02547:Vps13c	APN	9	67,815,301 (GRCm39)	missense	possibly damaging	0.83
IGL02640:Vps13c	APN	9	67,793,530 (GRCm39)	splice site	probably benign
IGL02673:Vps13c	APN	9	67,785,380 (GRCm39)	missense	probably damaging	1.00
IGL02721:Vps13c	APN	9	67,871,431 (GRCm39)	splice site	probably benign
IGL02834:Vps13c	APN	9	67,845,137 (GRCm39)	missense	probably benign
IGL02838:Vps13c	APN	9	67,883,133 (GRCm39)	missense	probably damaging	1.00
IGL03136:Vps13c	APN	9	67,857,592 (GRCm39)	missense	probably damaging	1.00
IGL03137:Vps13c	APN	9	67,797,662 (GRCm39)	missense	probably damaging	1.00
IGL03214:Vps13c	APN	9	67,804,477 (GRCm39)	missense	probably null	0.81
IGL03240:Vps13c	APN	9	67,862,329 (GRCm39)	missense	probably benign
IGL03303:Vps13c	APN	9	67,841,786 (GRCm39)	missense	probably benign	0.27
IGL03336:Vps13c	APN	9	67,858,924 (GRCm39)	missense	possibly damaging	0.76
IGL03366:Vps13c	APN	9	67,853,308 (GRCm39)	missense	probably benign	0.00
Derivative	UTSW	9	67,837,904 (GRCm39)	missense	possibly damaging	0.79
diversion	UTSW	9	67,817,515 (GRCm39)	missense	possibly damaging	0.93
introversion	UTSW	9	67,851,328 (GRCm39)	missense	probably damaging	0.98
Inversion	UTSW	9	67,810,121 (GRCm39)	critical splice acceptor site	probably null
subversion	UTSW	9	67,815,334 (GRCm39)	missense	probably damaging	1.00
Transversion	UTSW	9	67,841,783 (GRCm39)	missense	probably damaging	0.98
3-1:Vps13c	UTSW	9	67,843,655 (GRCm39)	missense	probably benign	0.00
IGL02991:Vps13c	UTSW	9	67,821,159 (GRCm39)	missense	probably damaging	1.00
PIT4802001:Vps13c	UTSW	9	67,845,068 (GRCm39)	missense	probably damaging	1.00
R0008:Vps13c	UTSW	9	67,826,544 (GRCm39)	missense	probably benign
R0206:Vps13c	UTSW	9	67,846,444 (GRCm39)	splice site	probably benign
R0288:Vps13c	UTSW	9	67,834,648 (GRCm39)	missense	probably damaging	0.99
R0324:Vps13c	UTSW	9	67,871,591 (GRCm39)	missense	possibly damaging	0.95
R0347:Vps13c	UTSW	9	67,817,515 (GRCm39)	missense	possibly damaging	0.93
R0374:Vps13c	UTSW	9	67,793,528 (GRCm39)	splice site	probably benign
R0388:Vps13c	UTSW	9	67,830,197 (GRCm39)	splice site	probably benign
R0409:Vps13c	UTSW	9	67,858,926 (GRCm39)	missense	probably benign	0.00
R0440:Vps13c	UTSW	9	67,880,143 (GRCm39)	missense	probably damaging	1.00
R0513:Vps13c	UTSW	9	67,838,017 (GRCm39)	missense	probably benign	0.02
R0520:Vps13c	UTSW	9	67,853,133 (GRCm39)	missense	possibly damaging	0.88
R0569:Vps13c	UTSW	9	67,881,001 (GRCm39)	missense	probably damaging	0.98
R0601:Vps13c	UTSW	9	67,834,754 (GRCm39)	missense	probably benign	0.12
R0659:Vps13c	UTSW	9	67,828,217 (GRCm39)	missense	probably benign	0.11
R0667:Vps13c	UTSW	9	67,858,855 (GRCm39)	nonsense	probably null
R0670:Vps13c	UTSW	9	67,833,139 (GRCm39)	missense	probably benign	0.35
R0698:Vps13c	UTSW	9	67,797,005 (GRCm39)	missense	probably benign	0.45
R0729:Vps13c	UTSW	9	67,868,931 (GRCm39)	missense	probably damaging	1.00
R0781:Vps13c	UTSW	9	67,879,285 (GRCm39)	missense	probably damaging	1.00
R0811:Vps13c	UTSW	9	67,841,758 (GRCm39)	missense	probably benign	0.06
R0812:Vps13c	UTSW	9	67,841,758 (GRCm39)	missense	probably benign	0.06
R0839:Vps13c	UTSW	9	67,806,020 (GRCm39)	missense	probably benign
R1373:Vps13c	UTSW	9	67,834,793 (GRCm39)	missense	probably damaging	0.99
R1396:Vps13c	UTSW	9	67,862,304 (GRCm39)	missense	probably benign	0.00
R1499:Vps13c	UTSW	9	67,864,787 (GRCm39)	missense	probably benign	0.00
R1556:Vps13c	UTSW	9	67,837,993 (GRCm39)	missense	probably damaging	0.98
R1560:Vps13c	UTSW	9	67,843,745 (GRCm39)	critical splice donor site	probably null
R1584:Vps13c	UTSW	9	67,800,394 (GRCm39)	missense	possibly damaging	0.74
R1654:Vps13c	UTSW	9	67,858,969 (GRCm39)	missense	probably damaging	1.00
R1674:Vps13c	UTSW	9	67,760,985 (GRCm39)	nonsense	probably null
R1676:Vps13c	UTSW	9	67,834,244 (GRCm39)	missense	probably benign	0.20
R1695:Vps13c	UTSW	9	67,879,357 (GRCm39)	nonsense	probably null
R1710:Vps13c	UTSW	9	67,818,811 (GRCm39)	missense	probably benign	0.00
R1769:Vps13c	UTSW	9	67,873,003 (GRCm39)	missense	probably benign	0.00
R1775:Vps13c	UTSW	9	67,788,729 (GRCm39)	missense	probably damaging	1.00
R1795:Vps13c	UTSW	9	67,801,267 (GRCm39)	nonsense	probably null
R1799:Vps13c	UTSW	9	67,851,399 (GRCm39)	missense	probably damaging	0.98
R1835:Vps13c	UTSW	9	67,900,295 (GRCm39)	missense	probably benign	0.08
R1903:Vps13c	UTSW	9	67,801,334 (GRCm39)	missense	probably damaging	1.00
R1944:Vps13c	UTSW	9	67,793,558 (GRCm39)	missense	probably damaging	1.00
R1945:Vps13c	UTSW	9	67,793,558 (GRCm39)	missense	probably damaging	1.00
R1951:Vps13c	UTSW	9	67,881,041 (GRCm39)	critical splice donor site	probably null
R1993:Vps13c	UTSW	9	67,883,138 (GRCm39)	missense	probably damaging	1.00
R2023:Vps13c	UTSW	9	67,843,567 (GRCm39)	splice site	probably benign
R2059:Vps13c	UTSW	9	67,768,115 (GRCm39)	missense	probably damaging	1.00
R2086:Vps13c	UTSW	9	67,857,571 (GRCm39)	missense	probably benign	0.29
R2120:Vps13c	UTSW	9	67,826,616 (GRCm39)	missense	possibly damaging	0.92
R2249:Vps13c	UTSW	9	67,895,335 (GRCm39)	critical splice donor site	probably null
R2257:Vps13c	UTSW	9	67,860,228 (GRCm39)	missense	possibly damaging	0.87
R2258:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2259:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2260:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2265:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2266:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2269:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2278:Vps13c	UTSW	9	67,846,354 (GRCm39)	missense	probably benign
R2306:Vps13c	UTSW	9	67,895,275 (GRCm39)	missense	probably damaging	0.99
R2327:Vps13c	UTSW	9	67,821,102 (GRCm39)	missense	probably damaging	0.98
R2349:Vps13c	UTSW	9	67,864,808 (GRCm39)	missense	possibly damaging	0.89
R2483:Vps13c	UTSW	9	67,883,189 (GRCm39)	critical splice donor site	probably null
R3031:Vps13c	UTSW	9	67,831,052 (GRCm39)	missense	probably benign	0.00
R3623:Vps13c	UTSW	9	67,883,189 (GRCm39)	critical splice donor site	probably null
R3870:Vps13c	UTSW	9	67,792,008 (GRCm39)	missense	probably benign	0.00
R4173:Vps13c	UTSW	9	67,843,595 (GRCm39)	missense	probably benign	0.00
R4445:Vps13c	UTSW	9	67,889,777 (GRCm39)	splice site	probably null
R4491:Vps13c	UTSW	9	67,817,475 (GRCm39)	missense	probably benign
R4505:Vps13c	UTSW	9	67,846,316 (GRCm39)	missense	probably benign	0.02
R4574:Vps13c	UTSW	9	67,858,965 (GRCm39)	missense	probably damaging	1.00
R4691:Vps13c	UTSW	9	67,860,217 (GRCm39)	missense	possibly damaging	0.95
R4766:Vps13c	UTSW	9	67,785,506 (GRCm39)	splice site	probably null
R4771:Vps13c	UTSW	9	67,836,821 (GRCm39)	missense	probably benign
R4801:Vps13c	UTSW	9	67,871,564 (GRCm39)	missense	probably damaging	1.00
R4802:Vps13c	UTSW	9	67,871,564 (GRCm39)	missense	probably damaging	1.00
R4962:Vps13c	UTSW	9	67,781,173 (GRCm39)	missense	probably damaging	1.00
R4995:Vps13c	UTSW	9	67,826,603 (GRCm39)	missense	probably benign	0.00
R5010:Vps13c	UTSW	9	67,823,661 (GRCm39)	missense	probably benign	0.19
R5183:Vps13c	UTSW	9	67,815,334 (GRCm39)	missense	probably damaging	1.00
R5226:Vps13c	UTSW	9	67,852,835 (GRCm39)	missense	probably benign	0.17
R5297:Vps13c	UTSW	9	67,785,413 (GRCm39)	missense	probably damaging	1.00
R5456:Vps13c	UTSW	9	67,834,729 (GRCm39)	missense	possibly damaging	0.53
R5494:Vps13c	UTSW	9	67,855,428 (GRCm39)	missense	probably benign	0.00
R5521:Vps13c	UTSW	9	67,858,721 (GRCm39)	missense	probably benign	0.08
R5524:Vps13c	UTSW	9	67,864,838 (GRCm39)	missense	probably damaging	1.00
R5685:Vps13c	UTSW	9	67,870,455 (GRCm39)	missense	possibly damaging	0.64
R5731:Vps13c	UTSW	9	67,802,661 (GRCm39)	missense	probably damaging	1.00
R5812:Vps13c	UTSW	9	67,889,777 (GRCm39)	splice site	probably benign
R5867:Vps13c	UTSW	9	67,889,904 (GRCm39)	splice site	probably null
R5893:Vps13c	UTSW	9	67,810,121 (GRCm39)	critical splice acceptor site	probably null
R5902:Vps13c	UTSW	9	67,841,729 (GRCm39)	missense	probably benign	0.00
R5957:Vps13c	UTSW	9	67,862,253 (GRCm39)	missense	probably damaging	1.00
R6076:Vps13c	UTSW	9	67,818,884 (GRCm39)	missense	probably damaging	1.00
R6187:Vps13c	UTSW	9	67,822,939 (GRCm39)	missense	probably damaging	1.00
R6268:Vps13c	UTSW	9	67,858,731 (GRCm39)	missense	probably benign	0.10
R6547:Vps13c	UTSW	9	67,880,647 (GRCm39)	missense	probably damaging	1.00
R6716:Vps13c	UTSW	9	67,858,749 (GRCm39)	missense	probably benign	0.00
R6837:Vps13c	UTSW	9	67,817,504 (GRCm39)	missense	probably benign
R6919:Vps13c	UTSW	9	67,834,734 (GRCm39)	missense	probably damaging	0.97
R7039:Vps13c	UTSW	9	67,845,045 (GRCm39)	missense	probably damaging	1.00
R7058:Vps13c	UTSW	9	67,831,110 (GRCm39)	missense	probably benign	0.39
R7082:Vps13c	UTSW	9	67,790,735 (GRCm39)	missense	probably damaging	1.00
R7195:Vps13c	UTSW	9	67,853,107 (GRCm39)	missense	possibly damaging	0.95
R7244:Vps13c	UTSW	9	67,797,086 (GRCm39)	missense	probably benign	0.00
R7300:Vps13c	UTSW	9	67,847,826 (GRCm39)	missense	probably benign	0.20
R7314:Vps13c	UTSW	9	67,850,622 (GRCm39)	splice site	probably null
R7352:Vps13c	UTSW	9	67,747,728 (GRCm39)	missense	possibly damaging	0.94
R7368:Vps13c	UTSW	9	67,821,355 (GRCm39)	missense	probably benign	0.23
R7411:Vps13c	UTSW	9	67,879,283 (GRCm39)	missense	probably damaging	0.98
R7497:Vps13c	UTSW	9	67,747,761 (GRCm39)	missense	probably damaging	1.00
R7516:Vps13c	UTSW	9	67,862,289 (GRCm39)	missense	possibly damaging	0.89
R7638:Vps13c	UTSW	9	67,852,791 (GRCm39)	missense	probably damaging	1.00
R7732:Vps13c	UTSW	9	67,847,798 (GRCm39)	missense	probably damaging	0.97
R7748:Vps13c	UTSW	9	67,870,371 (GRCm39)	missense	probably benign	0.03
R7779:Vps13c	UTSW	9	67,788,704 (GRCm39)	missense	probably damaging	1.00
R7788:Vps13c	UTSW	9	67,847,765 (GRCm39)	missense	probably benign	0.01
R7894:Vps13c	UTSW	9	67,834,265 (GRCm39)	missense	probably damaging	0.99
R8163:Vps13c	UTSW	9	67,857,720 (GRCm39)	missense	probably benign	0.08
R8165:Vps13c	UTSW	9	67,766,072 (GRCm39)	missense	probably benign	0.00
R8202:Vps13c	UTSW	9	67,851,328 (GRCm39)	missense	probably damaging	0.98
R8235:Vps13c	UTSW	9	67,863,063 (GRCm39)	missense	probably benign	0.01
R8235:Vps13c	UTSW	9	67,834,678 (GRCm39)	missense	probably damaging	1.00
R8253:Vps13c	UTSW	9	67,850,770 (GRCm39)	nonsense	probably null
R8261:Vps13c	UTSW	9	67,862,262 (GRCm39)	missense	probably damaging	1.00
R8348:Vps13c	UTSW	9	67,786,385 (GRCm39)	missense	possibly damaging	0.79
R8547:Vps13c	UTSW	9	67,852,848 (GRCm39)	missense	probably damaging	1.00
R8734:Vps13c	UTSW	9	67,880,685 (GRCm39)	missense	probably damaging	1.00
R8806:Vps13c	UTSW	9	67,853,110 (GRCm39)	missense	probably damaging	1.00
R8807:Vps13c	UTSW	9	67,766,122 (GRCm39)	missense	probably damaging	0.99
R8813:Vps13c	UTSW	9	67,778,566 (GRCm39)	missense	probably damaging	1.00
R8883:Vps13c	UTSW	9	67,855,479 (GRCm39)	missense	probably benign	0.10
R8885:Vps13c	UTSW	9	67,850,736 (GRCm39)	missense	probably benign
R8899:Vps13c	UTSW	9	67,841,783 (GRCm39)	missense	probably damaging	0.98
R8970:Vps13c	UTSW	9	67,852,803 (GRCm39)	missense	probably benign	0.11
R9007:Vps13c	UTSW	9	67,845,006 (GRCm39)	missense	probably benign	0.00
R9026:Vps13c	UTSW	9	67,861,863 (GRCm39)	missense	probably damaging	1.00
R9029:Vps13c	UTSW	9	67,855,429 (GRCm39)	missense	probably damaging	0.98
R9057:Vps13c	UTSW	9	67,828,209 (GRCm39)	missense	probably benign	0.00
R9105:Vps13c	UTSW	9	67,778,081 (GRCm39)	intron	probably benign
R9130:Vps13c	UTSW	9	67,836,805 (GRCm39)	missense	probably damaging	1.00
R9286:Vps13c	UTSW	9	67,880,203 (GRCm39)	missense	probably benign	0.00
R9338:Vps13c	UTSW	9	67,858,977 (GRCm39)	missense	probably damaging	1.00
R9432:Vps13c	UTSW	9	67,830,137 (GRCm39)	missense	probably benign	0.02
R9460:Vps13c	UTSW	9	67,837,904 (GRCm39)	missense	possibly damaging	0.79
R9464:Vps13c	UTSW	9	67,858,674 (GRCm39)	missense	probably damaging	1.00
R9561:Vps13c	UTSW	9	67,872,794 (GRCm39)	missense	probably damaging	1.00
R9609:Vps13c	UTSW	9	67,841,831 (GRCm39)	missense	probably damaging	1.00
R9622:Vps13c	UTSW	9	67,856,715 (GRCm39)	missense	probably damaging	1.00
R9665:Vps13c	UTSW	9	67,863,025 (GRCm39)	nonsense	probably null
R9731:Vps13c	UTSW	9	67,826,526 (GRCm39)	missense	probably benign
R9763:Vps13c	UTSW	9	67,818,860 (GRCm39)	missense	probably benign	0.00
R9774:Vps13c	UTSW	9	67,791,873 (GRCm39)	missense	possibly damaging	0.85
R9798:Vps13c	UTSW	9	67,826,646 (GRCm39)	missense	probably damaging	1.00
U24488:Vps13c	UTSW	9	67,813,198 (GRCm39)	missense	probably benign	0.13
X0021:Vps13c	UTSW	9	67,845,063 (GRCm39)	missense	probably damaging	0.99
X0058:Vps13c	UTSW	9	67,834,701 (GRCm39)	missense	probably damaging	1.00
X0065:Vps13c	UTSW	9	67,781,145 (GRCm39)	missense	probably damaging	1.00
Z1088:Vps13c	UTSW	9	67,821,257 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- TCTGCACTTAGAGACTTCGTG -3'
(R):5'- TTGTGAGACTATGGCCAAAGG -3'

Sequencing Primer
(F):5'- CTGCACTTAGAGACTTCGTGAGTTG -3'
(R):5'- AAGGCTAGACTCTTCTGAGGATCC -3'

Posted On

2014-06-23