Incidental Mutation 'R1848:Nbas'
| ID |
207936 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nbas
|
| Ensembl Gene |
ENSMUSG00000020576 |
| Gene Name |
neuroblastoma amplified sequence |
| Synonyms |
4933425L03Rik |
| MMRRC Submission |
039873-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1848 (G1)
|
| Quality Score |
209 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
13319134-13633812 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to C
at 13463598 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Alanine
at position 1295
(D1295A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036082
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042953]
|
| AlphaFold |
E9Q411 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000042953
AA Change: D1295A
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000036082
Gene: ENSMUSG00000020576
AA Change: D1295A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nbas_N
|
89 |
370 |
4.7e-171 |
PFAM |
|
low complexity region
|
463 |
475 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
667 |
N/A |
INTRINSIC |
|
Pfam:Sec39
|
725 |
1375 |
3.8e-34 |
PFAM |
|
low complexity region
|
1392 |
1404 |
N/A |
INTRINSIC |
|
low complexity region
|
1549 |
1566 |
N/A |
INTRINSIC |
|
low complexity region
|
2226 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2285 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.7888 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.2%
|
| Validation Efficiency |
98% (120/123) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]
|
| Allele List at MGI |
All alleles(10) : Targeted, other(2) Gene trapped(8)
|
| Other mutations in this stock |
Total: 120 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933402J07Rik |
C |
A |
8: 88,295,121 (GRCm39) |
Y86* |
probably null |
Het |
| Aadac |
A |
G |
3: 59,947,118 (GRCm39) |
E272G |
probably damaging |
Het |
| Abcc8 |
A |
T |
7: 45,816,326 (GRCm39) |
D271E |
probably benign |
Het |
| Acan |
T |
C |
7: 78,748,783 (GRCm39) |
F1185L |
probably benign |
Het |
| Adam1a |
A |
T |
5: 121,657,683 (GRCm39) |
C537S |
probably damaging |
Het |
| Ago2 |
A |
G |
15: 72,995,814 (GRCm39) |
V395A |
probably benign |
Het |
| Alox15 |
A |
G |
11: 70,241,578 (GRCm39) |
V101A |
probably damaging |
Het |
| Ankra2 |
T |
C |
13: 98,407,632 (GRCm39) |
I194T |
probably damaging |
Het |
| Apobec4 |
C |
A |
1: 152,631,981 (GRCm39) |
P3H |
probably damaging |
Het |
| Arid3b |
G |
T |
9: 57,703,960 (GRCm39) |
Y329* |
probably null |
Het |
| Atm |
A |
T |
9: 53,379,312 (GRCm39) |
S1993T |
probably benign |
Het |
| Bpgm |
T |
G |
6: 34,464,669 (GRCm39) |
S129A |
probably benign |
Het |
| Brat1 |
A |
G |
5: 140,704,264 (GRCm39) |
D839G |
possibly damaging |
Het |
| Ccdc15 |
A |
T |
9: 37,253,866 (GRCm39) |
S128T |
probably benign |
Het |
| Cd300lg |
A |
T |
11: 101,937,032 (GRCm39) |
|
probably benign |
Het |
| Cdc34b |
C |
A |
11: 94,633,303 (GRCm39) |
Q168K |
probably damaging |
Het |
| Celsr2 |
A |
T |
3: 108,308,626 (GRCm39) |
V1767E |
probably benign |
Het |
| Cep350 |
T |
C |
1: 155,829,397 (GRCm39) |
D169G |
probably benign |
Het |
| Col7a1 |
A |
T |
9: 108,798,633 (GRCm39) |
D1762V |
possibly damaging |
Het |
| Coro7 |
A |
G |
16: 4,448,298 (GRCm39) |
L724P |
probably damaging |
Het |
| Crb1 |
T |
A |
1: 139,164,750 (GRCm39) |
I1125F |
probably damaging |
Het |
| Ctif |
T |
A |
18: 75,653,012 (GRCm39) |
D415V |
probably damaging |
Het |
| Dab1 |
C |
T |
4: 104,588,948 (GRCm39) |
A524V |
probably benign |
Het |
| Dhrs2 |
A |
G |
14: 55,478,298 (GRCm39) |
D237G |
probably benign |
Het |
| Dhx9 |
T |
C |
1: 153,341,499 (GRCm39) |
Q582R |
probably damaging |
Het |
| Dnajc1 |
C |
T |
2: 18,224,524 (GRCm39) |
R443Q |
probably damaging |
Het |
| Dnm2 |
C |
T |
9: 21,416,977 (GRCm39) |
R837W |
possibly damaging |
Het |
| Dpf2 |
C |
A |
19: 5,956,643 (GRCm39) |
Q70H |
probably damaging |
Het |
| Dqx1 |
T |
A |
6: 83,043,088 (GRCm39) |
D608E |
probably damaging |
Het |
| Dync2h1 |
T |
A |
9: 7,049,166 (GRCm39) |
T3245S |
probably benign |
Het |
| Ect2l |
A |
G |
10: 18,075,781 (GRCm39) |
L35P |
probably damaging |
Het |
| Efcab5 |
A |
T |
11: 76,994,132 (GRCm39) |
L1285Q |
probably damaging |
Het |
| Eif4g1 |
G |
C |
16: 20,500,617 (GRCm39) |
R697P |
probably damaging |
Het |
| Emsy |
T |
A |
7: 98,250,028 (GRCm39) |
E753V |
probably damaging |
Het |
| Entpd3 |
A |
G |
9: 120,387,485 (GRCm39) |
I227M |
probably damaging |
Het |
| Epn1 |
T |
A |
7: 5,092,997 (GRCm39) |
V103E |
probably damaging |
Het |
| Esrra |
T |
C |
19: 6,889,378 (GRCm39) |
D337G |
probably benign |
Het |
| Fam83e |
A |
T |
7: 45,378,193 (GRCm39) |
K406* |
probably null |
Het |
| Fam83e |
A |
T |
7: 45,378,194 (GRCm39) |
K406M |
possibly damaging |
Het |
| Fat2 |
A |
G |
11: 55,202,384 (GRCm39) |
I230T |
probably damaging |
Het |
| Fbxl16 |
A |
G |
17: 26,035,420 (GRCm39) |
I6V |
probably benign |
Het |
| Fgf23 |
T |
C |
6: 127,050,156 (GRCm39) |
I55T |
probably damaging |
Het |
| Fibcd1 |
T |
A |
2: 31,711,561 (GRCm39) |
D288V |
probably damaging |
Het |
| Flnb |
T |
C |
14: 7,892,113 (GRCm38) |
I594T |
probably damaging |
Het |
| Gabbr2 |
T |
C |
4: 46,739,823 (GRCm39) |
E449G |
probably benign |
Het |
| Gbf1 |
T |
G |
19: 46,260,476 (GRCm39) |
S1130A |
possibly damaging |
Het |
| Gipc3 |
T |
C |
10: 81,177,099 (GRCm39) |
E157G |
probably damaging |
Het |
| Glra3 |
G |
T |
8: 56,393,942 (GRCm39) |
A18S |
probably benign |
Het |
| Gm6625 |
A |
C |
8: 89,873,462 (GRCm39) |
|
noncoding transcript |
Het |
| Gpx4 |
A |
G |
10: 79,891,870 (GRCm39) |
|
probably benign |
Het |
| Grb10 |
A |
G |
11: 11,896,029 (GRCm39) |
F264L |
possibly damaging |
Het |
| Grik3 |
T |
C |
4: 125,587,931 (GRCm39) |
Y684H |
probably damaging |
Het |
| Gstp1 |
C |
T |
19: 4,086,795 (GRCm39) |
|
probably benign |
Het |
| H2bc27 |
A |
T |
11: 58,839,928 (GRCm39) |
I55F |
possibly damaging |
Het |
| Haus8 |
G |
A |
8: 71,708,767 (GRCm39) |
|
probably benign |
Het |
| Hip1 |
G |
A |
5: 135,463,995 (GRCm39) |
|
probably null |
Het |
| Hspbap1 |
T |
A |
16: 35,639,134 (GRCm39) |
|
probably null |
Het |
| Htr2b |
T |
A |
1: 86,027,151 (GRCm39) |
I452F |
possibly damaging |
Het |
| Hydin |
T |
A |
8: 111,296,440 (GRCm39) |
H3656Q |
probably benign |
Het |
| Klb |
T |
A |
5: 65,506,180 (GRCm39) |
D142E |
probably benign |
Het |
| Lamb3 |
A |
T |
1: 193,016,924 (GRCm39) |
T777S |
possibly damaging |
Het |
| Lins1 |
C |
A |
7: 66,364,070 (GRCm39) |
T650K |
probably damaging |
Het |
| Loxhd1 |
A |
G |
18: 77,369,667 (GRCm39) |
K5R |
possibly damaging |
Het |
| Lpp |
G |
A |
16: 24,580,405 (GRCm39) |
M40I |
probably damaging |
Het |
| Mia2 |
A |
T |
12: 59,217,037 (GRCm39) |
|
probably benign |
Het |
| Miip |
A |
C |
4: 147,947,549 (GRCm39) |
F204V |
probably damaging |
Het |
| Mmp21 |
T |
C |
7: 133,278,882 (GRCm39) |
R323G |
probably benign |
Het |
| Mta3 |
T |
A |
17: 84,062,980 (GRCm39) |
|
probably benign |
Het |
| Myh1 |
A |
G |
11: 67,104,456 (GRCm39) |
K1004R |
probably benign |
Het |
| Myh14 |
T |
A |
7: 44,281,853 (GRCm39) |
I810F |
probably damaging |
Het |
| Niban3 |
T |
C |
8: 72,056,413 (GRCm39) |
M371T |
possibly damaging |
Het |
| Npr2 |
T |
G |
4: 43,632,384 (GRCm39) |
V67G |
probably benign |
Het |
| Oas1f |
C |
A |
5: 120,993,492 (GRCm39) |
Q235K |
probably damaging |
Het |
| Or12d17 |
T |
A |
17: 37,777,938 (GRCm39) |
S280R |
probably damaging |
Het |
| Or13a27 |
T |
A |
7: 139,925,900 (GRCm39) |
M1L |
probably benign |
Het |
| Or1p1 |
G |
T |
11: 74,180,039 (GRCm39) |
C189F |
probably damaging |
Het |
| Or52ae9 |
T |
C |
7: 103,390,381 (GRCm39) |
N22S |
probably benign |
Het |
| Or7e166 |
C |
T |
9: 19,624,386 (GRCm39) |
H88Y |
probably benign |
Het |
| Pafah2 |
GCCCC |
GCCCCC |
4: 134,152,852 (GRCm39) |
|
probably null |
Het |
| Pde1b |
A |
G |
15: 103,433,767 (GRCm39) |
|
probably null |
Het |
| Pdilt |
T |
C |
7: 119,088,607 (GRCm39) |
T465A |
probably benign |
Het |
| Plxnd1 |
T |
C |
6: 115,943,507 (GRCm39) |
H1233R |
probably damaging |
Het |
| Ppm1b |
T |
A |
17: 85,301,552 (GRCm39) |
M144K |
probably benign |
Het |
| Prkdc |
T |
C |
16: 15,625,922 (GRCm39) |
L3316S |
probably benign |
Het |
| Prm2 |
T |
A |
16: 10,609,455 (GRCm39) |
|
probably benign |
Het |
| Prmt7 |
T |
C |
8: 106,963,640 (GRCm39) |
V240A |
probably benign |
Het |
| Prx |
C |
A |
7: 27,218,313 (GRCm39) |
A938E |
possibly damaging |
Het |
| Rbm7 |
A |
G |
9: 48,402,194 (GRCm39) |
V131A |
probably benign |
Het |
| Ric1 |
T |
A |
19: 29,578,213 (GRCm39) |
|
probably null |
Het |
| Rnf150 |
A |
T |
8: 83,590,639 (GRCm39) |
M1L |
possibly damaging |
Het |
| Rnf20 |
C |
T |
4: 49,644,628 (GRCm39) |
R298W |
probably damaging |
Het |
| Rp1 |
T |
A |
1: 4,417,455 (GRCm39) |
Y1219F |
possibly damaging |
Het |
| Scn7a |
A |
G |
2: 66,514,357 (GRCm39) |
|
probably null |
Het |
| Sdad1 |
A |
G |
5: 92,440,510 (GRCm39) |
|
probably null |
Het |
| Septin9 |
T |
C |
11: 117,243,909 (GRCm39) |
|
probably benign |
Het |
| Serinc3 |
T |
C |
2: 163,487,409 (GRCm39) |
|
probably benign |
Het |
| Shc3 |
C |
T |
13: 51,615,424 (GRCm39) |
G178R |
probably damaging |
Het |
| Slc4a10 |
A |
T |
2: 62,146,950 (GRCm39) |
K1090M |
probably damaging |
Het |
| Slco1a1 |
T |
C |
6: 141,868,837 (GRCm39) |
I376V |
probably benign |
Het |
| Slmap |
A |
T |
14: 26,143,729 (GRCm39) |
F719L |
probably benign |
Het |
| Smgc |
A |
G |
15: 91,743,956 (GRCm39) |
N573D |
possibly damaging |
Het |
| Spx |
G |
A |
6: 142,359,805 (GRCm39) |
|
probably null |
Het |
| Srrt |
C |
G |
5: 137,295,207 (GRCm39) |
E308Q |
probably damaging |
Het |
| Tas2r130 |
T |
A |
6: 131,607,560 (GRCm39) |
R78S |
probably benign |
Het |
| Tchhl1 |
A |
G |
3: 93,378,408 (GRCm39) |
R371G |
probably damaging |
Het |
| Teddm2 |
C |
T |
1: 153,726,194 (GRCm39) |
A174T |
probably benign |
Het |
| Tktl2 |
G |
A |
8: 66,964,999 (GRCm39) |
V186M |
probably damaging |
Het |
| Trim33 |
T |
C |
3: 103,231,956 (GRCm39) |
|
probably benign |
Het |
| Tspan31 |
A |
G |
10: 126,905,327 (GRCm39) |
V40A |
probably damaging |
Het |
| Uevld |
A |
G |
7: 46,594,975 (GRCm39) |
|
probably benign |
Het |
| Vcl |
G |
T |
14: 21,059,063 (GRCm39) |
A560S |
probably benign |
Het |
| Vmn2r24 |
T |
A |
6: 123,793,183 (GRCm39) |
C837S |
probably damaging |
Het |
| Vmn2r57 |
C |
T |
7: 41,077,531 (GRCm39) |
V212M |
probably damaging |
Het |
| Vps13c |
A |
G |
9: 67,843,622 (GRCm39) |
T1968A |
probably benign |
Het |
| Vtn |
A |
G |
11: 78,391,393 (GRCm39) |
R269G |
probably damaging |
Het |
| Wdcp |
G |
A |
12: 4,900,245 (GRCm39) |
V34I |
possibly damaging |
Het |
| Zc3h14 |
A |
G |
12: 98,719,091 (GRCm39) |
D152G |
possibly damaging |
Het |
| Zfp189 |
C |
T |
4: 49,529,266 (GRCm39) |
P123L |
probably benign |
Het |
| Zfp318 |
T |
C |
17: 46,716,981 (GRCm39) |
S1038P |
possibly damaging |
Het |
| Zfp873 |
A |
G |
10: 81,896,406 (GRCm39) |
D416G |
probably benign |
Het |
|
| Other mutations in Nbas |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Nbas
|
APN |
12 |
13,503,076 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL00712:Nbas
|
APN |
12 |
13,412,626 (GRCm39) |
splice site |
probably benign |
|
|
IGL00808:Nbas
|
APN |
12 |
13,616,121 (GRCm39) |
splice site |
probably benign |
|
|
IGL00915:Nbas
|
APN |
12 |
13,424,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL00923:Nbas
|
APN |
12 |
13,386,285 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01152:Nbas
|
APN |
12 |
13,410,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Nbas
|
APN |
12 |
13,533,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Nbas
|
APN |
12 |
13,429,650 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01799:Nbas
|
APN |
12 |
13,374,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL01812:Nbas
|
APN |
12 |
13,503,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01934:Nbas
|
APN |
12 |
13,339,880 (GRCm39) |
splice site |
probably benign |
|
|
IGL02093:Nbas
|
APN |
12 |
13,610,963 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02115:Nbas
|
APN |
12 |
13,367,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL02175:Nbas
|
APN |
12 |
13,616,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02268:Nbas
|
APN |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02483:Nbas
|
APN |
12 |
13,374,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02539:Nbas
|
APN |
12 |
13,322,704 (GRCm39) |
splice site |
probably benign |
|
|
IGL02557:Nbas
|
APN |
12 |
13,411,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Nbas
|
APN |
12 |
13,360,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Nbas
|
APN |
12 |
13,412,542 (GRCm39) |
missense |
probably benign |
|
|
IGL03131:Nbas
|
APN |
12 |
13,329,417 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03214:Nbas
|
APN |
12 |
13,381,111 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Nbas
|
APN |
12 |
13,374,349 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03368:Nbas
|
APN |
12 |
13,378,452 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03372:Nbas
|
APN |
12 |
13,584,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03391:Nbas
|
APN |
12 |
13,533,750 (GRCm39) |
missense |
probably benign |
0.28 |
|
medvedev
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
oligarchs
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
putin
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):Nbas
|
UTSW |
12 |
13,338,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Nbas
|
UTSW |
12 |
13,440,958 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0076:Nbas
|
UTSW |
12 |
13,374,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Nbas
|
UTSW |
12 |
13,323,877 (GRCm39) |
splice site |
probably benign |
|
|
R0371:Nbas
|
UTSW |
12 |
13,381,096 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0449:Nbas
|
UTSW |
12 |
13,569,109 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0791:Nbas
|
UTSW |
12 |
13,532,634 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0931:Nbas
|
UTSW |
12 |
13,381,115 (GRCm39) |
splice site |
probably benign |
|
|
R1236:Nbas
|
UTSW |
12 |
13,319,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1371:Nbas
|
UTSW |
12 |
13,532,379 (GRCm39) |
splice site |
probably benign |
|
|
R1567:Nbas
|
UTSW |
12 |
13,335,279 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1587:Nbas
|
UTSW |
12 |
13,608,686 (GRCm39) |
missense |
probably benign |
|
|
R1719:Nbas
|
UTSW |
12 |
13,610,978 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1747:Nbas
|
UTSW |
12 |
13,385,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1777:Nbas
|
UTSW |
12 |
13,563,563 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1856:Nbas
|
UTSW |
12 |
13,524,230 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1891:Nbas
|
UTSW |
12 |
13,440,973 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1911:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R1912:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R2006:Nbas
|
UTSW |
12 |
13,464,742 (GRCm39) |
splice site |
probably null |
|
|
R2054:Nbas
|
UTSW |
12 |
13,524,207 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2065:Nbas
|
UTSW |
12 |
13,616,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2089:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2156:Nbas
|
UTSW |
12 |
13,491,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2164:Nbas
|
UTSW |
12 |
13,380,647 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R2339:Nbas
|
UTSW |
12 |
13,412,593 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2398:Nbas
|
UTSW |
12 |
13,482,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3806:Nbas
|
UTSW |
12 |
13,532,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Nbas
|
UTSW |
12 |
13,329,415 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4019:Nbas
|
UTSW |
12 |
13,532,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4083:Nbas
|
UTSW |
12 |
13,524,192 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4201:Nbas
|
UTSW |
12 |
13,424,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4231:Nbas
|
UTSW |
12 |
13,443,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4552:Nbas
|
UTSW |
12 |
13,385,938 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4560:Nbas
|
UTSW |
12 |
13,633,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4728:Nbas
|
UTSW |
12 |
13,338,740 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4752:Nbas
|
UTSW |
12 |
13,532,538 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4832:Nbas
|
UTSW |
12 |
13,533,740 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4874:Nbas
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4988:Nbas
|
UTSW |
12 |
13,458,266 (GRCm39) |
missense |
probably benign |
0.45 |
|
R5020:Nbas
|
UTSW |
12 |
13,424,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5079:Nbas
|
UTSW |
12 |
13,424,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5129:Nbas
|
UTSW |
12 |
13,440,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5239:Nbas
|
UTSW |
12 |
13,491,519 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5299:Nbas
|
UTSW |
12 |
13,491,926 (GRCm39) |
nonsense |
probably null |
|
|
R5351:Nbas
|
UTSW |
12 |
13,610,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5389:Nbas
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5436:Nbas
|
UTSW |
12 |
13,424,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5654:Nbas
|
UTSW |
12 |
13,633,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Nbas
|
UTSW |
12 |
13,386,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5842:Nbas
|
UTSW |
12 |
13,319,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5959:Nbas
|
UTSW |
12 |
13,338,802 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5982:Nbas
|
UTSW |
12 |
13,443,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6238:Nbas
|
UTSW |
12 |
13,532,596 (GRCm39) |
missense |
probably benign |
|
|
R6270:Nbas
|
UTSW |
12 |
13,374,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6363:Nbas
|
UTSW |
12 |
13,532,577 (GRCm39) |
missense |
probably benign |
|
|
R6424:Nbas
|
UTSW |
12 |
13,465,734 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6458:Nbas
|
UTSW |
12 |
13,338,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Nbas
|
UTSW |
12 |
13,455,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6654:Nbas
|
UTSW |
12 |
13,533,875 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Nbas
|
UTSW |
12 |
13,335,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Nbas
|
UTSW |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7197:Nbas
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7378:Nbas
|
UTSW |
12 |
13,324,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7393:Nbas
|
UTSW |
12 |
13,443,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7425:Nbas
|
UTSW |
12 |
13,519,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7446:Nbas
|
UTSW |
12 |
13,443,499 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7481:Nbas
|
UTSW |
12 |
13,406,960 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7535:Nbas
|
UTSW |
12 |
13,329,390 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7626:Nbas
|
UTSW |
12 |
13,608,661 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7678:Nbas
|
UTSW |
12 |
13,465,662 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7912:Nbas
|
UTSW |
12 |
13,455,458 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7964:Nbas
|
UTSW |
12 |
13,406,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8193:Nbas
|
UTSW |
12 |
13,483,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8325:Nbas
|
UTSW |
12 |
13,338,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8405:Nbas
|
UTSW |
12 |
13,329,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8437:Nbas
|
UTSW |
12 |
13,616,251 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8559:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8684:Nbas
|
UTSW |
12 |
13,386,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Nbas
|
UTSW |
12 |
13,402,875 (GRCm39) |
splice site |
probably benign |
|
|
R8921:Nbas
|
UTSW |
12 |
13,463,590 (GRCm39) |
missense |
probably benign |
|
|
R8956:Nbas
|
UTSW |
12 |
13,482,923 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9083:Nbas
|
UTSW |
12 |
13,385,856 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9172:Nbas
|
UTSW |
12 |
13,424,751 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9430:Nbas
|
UTSW |
12 |
13,371,654 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9627:Nbas
|
UTSW |
12 |
13,350,203 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9649:Nbas
|
UTSW |
12 |
13,633,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF013:Nbas
|
UTSW |
12 |
13,329,409 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
T0722:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Nbas
|
UTSW |
12 |
13,533,877 (GRCm39) |
missense |
probably benign |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATCTCTTCCAAGTCCTGGGG -3'
(R):5'- AGAGATAAACTATAGCACCTGAGTC -3'
Sequencing Primer
(F):5'- GGGGATTTCCATGCATAAAAAGTAG -3'
(R):5'- TACACGCTTGCTACTAACAAAATG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation