Incidental Mutation 'R0116:Abcc12'
| ID |
20806 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abcc12
|
| Ensembl Gene |
ENSMUSG00000036872 |
| Gene Name |
ATP-binding cassette, sub-family C member 12 |
| Synonyms |
MRP9, 4930467B22Rik |
| MMRRC Submission |
038402-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.061)
|
| Stock # |
R0116 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
8 |
| Chromosomal Location |
87231197-87307317 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 87261627 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Phenylalanine
at position 668
(S668F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114582
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080115]
[ENSMUST00000129898]
[ENSMUST00000131423]
[ENSMUST00000131806]
[ENSMUST00000152438]
[ENSMUST00000156610]
|
| AlphaFold |
Q80WJ6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080115
AA Change: S668F
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000079014
Gene: ENSMUSG00000036872
AA Change: S668F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
3.6e-19 |
PFAM |
|
AAA
|
506 |
679 |
3.33e-13 |
SMART |
|
low complexity region
|
739 |
752 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
791 |
1079 |
1.3e-26 |
PFAM |
|
AAA
|
1153 |
1346 |
1.07e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129898
AA Change: S668F
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000122577
Gene: ENSMUSG00000036872
AA Change: S668F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
1.2e-19 |
PFAM |
|
AAA
|
506 |
679 |
3.33e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131423
AA Change: S668F
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000122402
Gene: ENSMUSG00000036872
AA Change: S668F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
1.1e-21 |
PFAM |
|
AAA
|
506 |
679 |
3.33e-13 |
SMART |
|
low complexity region
|
739 |
752 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
792 |
1077 |
1.6e-34 |
PFAM |
|
AAA
|
1153 |
1346 |
1.07e-11 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131806
AA Change: S668F
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000116866
Gene: ENSMUSG00000036872
AA Change: S668F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
1.3e-19 |
PFAM |
|
AAA
|
506 |
679 |
3.33e-13 |
SMART |
|
low complexity region
|
739 |
752 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152438
AA Change: S668F
PolyPhen 2
Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)
|
| SMART Domains |
Protein: ENSMUSP00000114582
Gene: ENSMUSG00000036872
AA Change: S668F
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
1.2e-19 |
PFAM |
|
AAA
|
506 |
679 |
3.33e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156066
|
| SMART Domains |
Protein: ENSMUSP00000120282
Gene: ENSMUSG00000036872
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
38 |
N/A |
INTRINSIC |
|
Pfam:ABC_membrane
|
78 |
363 |
3.8e-35 |
PFAM |
|
Pfam:ABC_tran
|
430 |
508 |
5.7e-16 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156610
|
| SMART Domains |
Protein: ENSMUSP00000123578
Gene: ENSMUSG00000036872
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ABC_membrane
|
123 |
392 |
5.9e-20 |
PFAM |
|
AAA
|
506 |
661 |
1.07e-7 |
SMART |
|
| Meta Mutation Damage Score |
0.0628 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 94.2%
|
| Validation Efficiency |
94% (95/101) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931406C07Rik |
A |
T |
9: 15,202,066 (GRCm39) |
V152E |
probably damaging |
Het |
| Abca5 |
T |
G |
11: 110,167,331 (GRCm39) |
E1495A |
probably damaging |
Het |
| Adgrl4 |
A |
T |
3: 151,223,247 (GRCm39) |
T608S |
probably benign |
Het |
| Angel2 |
G |
A |
1: 190,673,187 (GRCm39) |
D255N |
probably benign |
Het |
| Apob |
T |
A |
12: 8,039,113 (GRCm39) |
|
probably benign |
Het |
| Arfgef2 |
A |
T |
2: 166,715,603 (GRCm39) |
R1349S |
probably damaging |
Het |
| Atp2b2 |
C |
T |
6: 113,770,656 (GRCm39) |
V418I |
probably damaging |
Het |
| Birc6 |
C |
A |
17: 74,930,741 (GRCm39) |
|
probably benign |
Het |
| Capn13 |
T |
A |
17: 73,658,519 (GRCm39) |
Y183F |
probably damaging |
Het |
| Cngb1 |
A |
G |
8: 95,987,266 (GRCm39) |
S352P |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,741,273 (GRCm39) |
S720P |
probably damaging |
Het |
| Cpa4 |
C |
T |
6: 30,579,657 (GRCm39) |
R155W |
probably damaging |
Het |
| Dapk1 |
A |
G |
13: 60,908,914 (GRCm39) |
I1176V |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,949,132 (GRCm39) |
E2959G |
probably benign |
Het |
| Dnah7b |
T |
A |
1: 46,252,520 (GRCm39) |
I1734N |
possibly damaging |
Het |
| Dnajb7 |
A |
G |
15: 81,291,555 (GRCm39) |
Y261H |
probably benign |
Het |
| Dock2 |
T |
C |
11: 34,579,392 (GRCm39) |
|
probably benign |
Het |
| Dyrk3 |
A |
T |
1: 131,057,576 (GRCm39) |
V199E |
probably damaging |
Het |
| F2r |
G |
T |
13: 95,740,994 (GRCm39) |
C180* |
probably null |
Het |
| F5 |
A |
G |
1: 164,012,483 (GRCm39) |
S466G |
probably benign |
Het |
| Fbn2 |
A |
T |
18: 58,235,445 (GRCm39) |
C677* |
probably null |
Het |
| Fbxo41 |
A |
G |
6: 85,454,890 (GRCm39) |
S673P |
probably damaging |
Het |
| Fhad1 |
G |
T |
4: 141,667,406 (GRCm39) |
H639N |
probably benign |
Het |
| Fmnl3 |
G |
C |
15: 99,220,619 (GRCm39) |
|
probably benign |
Het |
| Foxa2 |
A |
G |
2: 147,885,481 (GRCm39) |
S270P |
probably damaging |
Het |
| Fxyd7 |
C |
T |
7: 30,746,793 (GRCm39) |
|
probably null |
Het |
| Gm5225 |
A |
G |
17: 24,243,032 (GRCm39) |
D67G |
probably benign |
Het |
| Grik3 |
G |
A |
4: 125,564,349 (GRCm39) |
E444K |
probably benign |
Het |
| Gsdma2 |
A |
G |
11: 98,540,009 (GRCm39) |
K44E |
probably damaging |
Het |
| Haus1 |
T |
A |
18: 77,849,770 (GRCm39) |
K130* |
probably null |
Het |
| Heg1 |
A |
G |
16: 33,556,028 (GRCm39) |
|
probably benign |
Het |
| Hormad2 |
A |
G |
11: 4,362,206 (GRCm39) |
|
probably benign |
Het |
| Hsd17b3 |
G |
A |
13: 64,206,403 (GRCm39) |
R300C |
possibly damaging |
Het |
| Irf5 |
T |
C |
6: 29,536,108 (GRCm39) |
F374S |
probably damaging |
Het |
| Itch |
A |
G |
2: 155,059,903 (GRCm39) |
|
probably benign |
Het |
| Jade2 |
A |
T |
11: 51,722,136 (GRCm39) |
L139Q |
probably damaging |
Het |
| Kif5c |
G |
A |
2: 49,642,251 (GRCm39) |
|
probably benign |
Het |
| Lama1 |
T |
C |
17: 68,083,918 (GRCm39) |
Y1387H |
probably benign |
Het |
| Larp4b |
A |
G |
13: 9,220,724 (GRCm39) |
R658G |
probably damaging |
Het |
| Mcph1 |
C |
T |
8: 18,838,264 (GRCm39) |
L729F |
probably benign |
Het |
| Me1 |
A |
T |
9: 86,536,720 (GRCm39) |
N118K |
probably benign |
Het |
| Med13 |
A |
G |
11: 86,210,723 (GRCm39) |
L473S |
probably damaging |
Het |
| Mgam |
T |
A |
6: 40,635,921 (GRCm39) |
Y359N |
probably damaging |
Het |
| Morc2b |
A |
G |
17: 33,356,015 (GRCm39) |
S586P |
probably damaging |
Het |
| Mthfr |
A |
G |
4: 148,135,980 (GRCm39) |
D310G |
probably benign |
Het |
| Mtmr7 |
A |
T |
8: 41,034,447 (GRCm39) |
|
probably benign |
Het |
| Mtus1 |
A |
G |
8: 41,451,514 (GRCm39) |
|
probably benign |
Het |
| Mus81 |
G |
T |
19: 5,536,552 (GRCm39) |
A138D |
probably damaging |
Het |
| Myom2 |
A |
T |
8: 15,167,633 (GRCm39) |
I1073F |
probably damaging |
Het |
| Nhsl1 |
A |
T |
10: 18,400,990 (GRCm39) |
K739* |
probably null |
Het |
| Nlrp4d |
T |
A |
7: 10,108,818 (GRCm39) |
K762N |
probably benign |
Het |
| Nrap |
T |
C |
19: 56,343,978 (GRCm39) |
Y724C |
probably damaging |
Het |
| Ogn |
A |
T |
13: 49,774,514 (GRCm39) |
Y219F |
possibly damaging |
Het |
| Or6c212 |
T |
A |
10: 129,558,846 (GRCm39) |
D189V |
probably damaging |
Het |
| Or8b56 |
T |
C |
9: 38,739,860 (GRCm39) |
L291P |
probably damaging |
Het |
| Or8g30 |
A |
T |
9: 39,230,160 (GRCm39) |
I250N |
probably damaging |
Het |
| Padi2 |
T |
C |
4: 140,653,550 (GRCm39) |
V180A |
probably benign |
Het |
| Papss2 |
C |
T |
19: 32,615,768 (GRCm39) |
R167* |
probably null |
Het |
| Pcbp2 |
T |
C |
15: 102,382,670 (GRCm39) |
|
probably benign |
Het |
| Per1 |
T |
A |
11: 68,992,706 (GRCm39) |
|
probably benign |
Het |
| Pik3ca |
T |
C |
3: 32,514,094 (GRCm39) |
I860T |
probably damaging |
Het |
| Pkdrej |
G |
A |
15: 85,701,746 (GRCm39) |
Q1397* |
probably null |
Het |
| Plce1 |
T |
C |
19: 38,710,265 (GRCm39) |
V1133A |
probably benign |
Het |
| Pnma8a |
T |
G |
7: 16,694,625 (GRCm39) |
V160G |
probably damaging |
Het |
| Prss12 |
T |
C |
3: 123,276,423 (GRCm39) |
C351R |
probably damaging |
Het |
| Qprt |
A |
T |
7: 126,708,269 (GRCm39) |
L54Q |
probably damaging |
Het |
| Raf1 |
C |
T |
6: 115,603,344 (GRCm39) |
S165N |
probably damaging |
Het |
| Rere |
A |
G |
4: 150,701,433 (GRCm39) |
N1271S |
probably benign |
Het |
| Rnasel |
T |
A |
1: 153,630,258 (GRCm39) |
L258H |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,724,807 (GRCm39) |
D2502G |
probably damaging |
Het |
| Ryr3 |
G |
A |
2: 112,633,510 (GRCm39) |
S2081L |
probably damaging |
Het |
| Sc5d |
G |
T |
9: 42,171,155 (GRCm39) |
Y11* |
probably null |
Het |
| Slc25a29 |
A |
C |
12: 108,793,017 (GRCm39) |
L187R |
possibly damaging |
Het |
| Slc2a7 |
G |
A |
4: 150,252,721 (GRCm39) |
V454M |
probably benign |
Het |
| Slco1b2 |
A |
T |
6: 141,615,114 (GRCm39) |
T340S |
probably benign |
Het |
| Smarcc1 |
A |
G |
9: 109,976,172 (GRCm39) |
N153S |
possibly damaging |
Het |
| Snx1 |
C |
A |
9: 65,995,821 (GRCm39) |
E516* |
probably null |
Het |
| Sptlc2 |
T |
C |
12: 87,403,454 (GRCm39) |
D115G |
probably benign |
Het |
| Stard9 |
A |
G |
2: 120,464,736 (GRCm39) |
N67S |
probably damaging |
Het |
| Styxl2 |
A |
C |
1: 165,927,270 (GRCm39) |
S781A |
probably benign |
Het |
| Swap70 |
G |
A |
7: 109,872,489 (GRCm39) |
R368H |
probably benign |
Het |
| Tcaf3 |
T |
C |
6: 42,568,284 (GRCm39) |
K691E |
probably benign |
Het |
| Tmco4 |
T |
C |
4: 138,781,231 (GRCm39) |
F465S |
probably damaging |
Het |
| Tmem245 |
A |
G |
4: 56,926,213 (GRCm39) |
S290P |
probably benign |
Het |
| Top2a |
T |
C |
11: 98,894,416 (GRCm39) |
T972A |
probably benign |
Het |
| Tpr |
T |
A |
1: 150,285,898 (GRCm39) |
S527R |
probably damaging |
Het |
| Traf2 |
T |
C |
2: 25,409,621 (GRCm39) |
D443G |
probably damaging |
Het |
| Trim40 |
A |
T |
17: 37,194,039 (GRCm39) |
|
probably null |
Het |
| Trim42 |
A |
T |
9: 97,245,456 (GRCm39) |
I448N |
possibly damaging |
Het |
| Ttll9 |
G |
A |
2: 152,825,054 (GRCm39) |
V78M |
probably damaging |
Het |
| Vav1 |
C |
T |
17: 57,603,039 (GRCm39) |
L88F |
probably damaging |
Het |
| Vps13b |
A |
G |
15: 35,423,301 (GRCm39) |
D207G |
probably damaging |
Het |
| Wdsub1 |
A |
G |
2: 59,707,009 (GRCm39) |
|
probably null |
Het |
| Zfp799 |
A |
G |
17: 33,040,009 (GRCm39) |
W85R |
possibly damaging |
Het |
| Zfp839 |
A |
T |
12: 110,825,203 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Abcc12 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01362:Abcc12
|
APN |
8 |
87,261,322 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL01504:Abcc12
|
APN |
8 |
87,284,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01593:Abcc12
|
APN |
8 |
87,284,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02164:Abcc12
|
APN |
8 |
87,254,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02173:Abcc12
|
APN |
8 |
87,293,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02175:Abcc12
|
APN |
8 |
87,261,642 (GRCm39) |
splice site |
probably null |
|
|
IGL02405:Abcc12
|
APN |
8 |
87,284,782 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02620:Abcc12
|
APN |
8 |
87,231,943 (GRCm39) |
splice site |
probably null |
|
|
IGL02635:Abcc12
|
APN |
8 |
87,236,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03241:Abcc12
|
APN |
8 |
87,236,436 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
PIT4544001:Abcc12
|
UTSW |
8 |
87,231,875 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R0023:Abcc12
|
UTSW |
8 |
87,264,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0023:Abcc12
|
UTSW |
8 |
87,264,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Abcc12
|
UTSW |
8 |
87,258,197 (GRCm39) |
missense |
probably benign |
|
|
R0131:Abcc12
|
UTSW |
8 |
87,258,197 (GRCm39) |
missense |
probably benign |
|
|
R0132:Abcc12
|
UTSW |
8 |
87,258,197 (GRCm39) |
missense |
probably benign |
|
|
R0308:Abcc12
|
UTSW |
8 |
87,284,381 (GRCm39) |
splice site |
probably benign |
|
|
R0589:Abcc12
|
UTSW |
8 |
87,287,101 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1451:Abcc12
|
UTSW |
8 |
87,284,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1564:Abcc12
|
UTSW |
8 |
87,244,115 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1740:Abcc12
|
UTSW |
8 |
87,236,400 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1740:Abcc12
|
UTSW |
8 |
87,232,126 (GRCm39) |
nonsense |
probably null |
|
|
R1970:Abcc12
|
UTSW |
8 |
87,253,910 (GRCm39) |
missense |
probably benign |
0.27 |
|
R2017:Abcc12
|
UTSW |
8 |
87,290,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2026:Abcc12
|
UTSW |
8 |
87,284,862 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2402:Abcc12
|
UTSW |
8 |
87,235,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3085:Abcc12
|
UTSW |
8 |
87,270,536 (GRCm39) |
splice site |
probably benign |
|
|
R3115:Abcc12
|
UTSW |
8 |
87,266,653 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3176:Abcc12
|
UTSW |
8 |
87,233,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3276:Abcc12
|
UTSW |
8 |
87,233,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3847:Abcc12
|
UTSW |
8 |
87,280,020 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3911:Abcc12
|
UTSW |
8 |
87,255,048 (GRCm39) |
splice site |
probably benign |
|
|
R4031:Abcc12
|
UTSW |
8 |
87,244,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4297:Abcc12
|
UTSW |
8 |
87,258,154 (GRCm39) |
splice site |
probably null |
|
|
R4298:Abcc12
|
UTSW |
8 |
87,258,154 (GRCm39) |
splice site |
probably null |
|
|
R4299:Abcc12
|
UTSW |
8 |
87,258,154 (GRCm39) |
splice site |
probably null |
|
|
R4688:Abcc12
|
UTSW |
8 |
87,275,323 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4810:Abcc12
|
UTSW |
8 |
87,287,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:Abcc12
|
UTSW |
8 |
87,265,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4892:Abcc12
|
UTSW |
8 |
87,236,431 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5288:Abcc12
|
UTSW |
8 |
87,293,168 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5303:Abcc12
|
UTSW |
8 |
87,236,415 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5332:Abcc12
|
UTSW |
8 |
87,251,459 (GRCm39) |
splice site |
probably null |
|
|
R5386:Abcc12
|
UTSW |
8 |
87,244,118 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5457:Abcc12
|
UTSW |
8 |
87,236,473 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5900:Abcc12
|
UTSW |
8 |
87,293,149 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6035:Abcc12
|
UTSW |
8 |
87,244,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6035:Abcc12
|
UTSW |
8 |
87,244,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6291:Abcc12
|
UTSW |
8 |
87,293,173 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6518:Abcc12
|
UTSW |
8 |
87,235,718 (GRCm39) |
|
|
|
|
R6677:Abcc12
|
UTSW |
8 |
87,261,381 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7258:Abcc12
|
UTSW |
8 |
87,287,486 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7411:Abcc12
|
UTSW |
8 |
87,287,479 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7619:Abcc12
|
UTSW |
8 |
87,293,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7808:Abcc12
|
UTSW |
8 |
87,234,568 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7828:Abcc12
|
UTSW |
8 |
87,254,904 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7834:Abcc12
|
UTSW |
8 |
87,284,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7834:Abcc12
|
UTSW |
8 |
87,258,179 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7939:Abcc12
|
UTSW |
8 |
87,275,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7989:Abcc12
|
UTSW |
8 |
87,232,108 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8290:Abcc12
|
UTSW |
8 |
87,238,911 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8681:Abcc12
|
UTSW |
8 |
87,231,908 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R8795:Abcc12
|
UTSW |
8 |
87,258,213 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8811:Abcc12
|
UTSW |
8 |
87,280,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8939:Abcc12
|
UTSW |
8 |
87,243,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8940:Abcc12
|
UTSW |
8 |
87,287,440 (GRCm39) |
missense |
probably benign |
0.45 |
|
R9711:Abcc12
|
UTSW |
8 |
87,275,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Abcc12
|
UTSW |
8 |
87,279,920 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Abcc12
|
UTSW |
8 |
87,286,908 (GRCm39) |
splice site |
probably null |
|
|
Z1176:Abcc12
|
UTSW |
8 |
87,277,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Abcc12
|
UTSW |
8 |
87,254,013 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGGCGGGACTCTTAATCCCAC -3'
(R):5'- TTCCAAACCTTGGCCTCCACAATAG -3'
Sequencing Primer
(F):5'- ACTCACCAGGCAGGTGTG -3'
(R):5'- cagacaattttgctcatcacaac -3'
|
| Posted On |
2013-04-11 |
Incidental Mutation