Incidental Mutation 'R1851:Chd5'
| ID |
208073 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd5
|
| Ensembl Gene |
ENSMUSG00000005045 |
| Gene Name |
chromodomain helicase DNA binding protein 5 |
| Synonyms |
B230399N07Rik, 4930532L22Rik |
| MMRRC Submission |
039875-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1851 (G1)
|
| Quality Score |
195 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
152423108-152474651 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 152462727 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Glycine
at position 1356
(S1356G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132600
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000005175]
[ENSMUST00000030775]
[ENSMUST00000164662]
|
| AlphaFold |
A2A8L1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000005175
AA Change: S1393G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000005175
Gene: ENSMUSG00000005045
AA Change: S1393G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
46 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
Pfam:CHDNT
|
149 |
203 |
2e-32 |
PFAM |
|
low complexity region
|
209 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
256 |
273 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
323 |
333 |
N/A |
INTRINSIC |
|
PHD
|
347 |
390 |
1.09e-14 |
SMART |
|
RING
|
348 |
389 |
4.48e-1 |
SMART |
|
low complexity region
|
400 |
416 |
N/A |
INTRINSIC |
|
PHD
|
420 |
463 |
3.29e-14 |
SMART |
|
RING
|
421 |
462 |
4.15e0 |
SMART |
|
CHROMO
|
468 |
548 |
2.52e-13 |
SMART |
|
CHROMO
|
592 |
649 |
1.34e-8 |
SMART |
|
low complexity region
|
657 |
678 |
N/A |
INTRINSIC |
|
DEXDc
|
698 |
910 |
8.34e-33 |
SMART |
|
low complexity region
|
1023 |
1038 |
N/A |
INTRINSIC |
|
HELICc
|
1056 |
1140 |
4.02e-26 |
SMART |
|
DUF1087
|
1297 |
1361 |
2.78e-33 |
SMART |
|
DUF1086
|
1374 |
1533 |
5.11e-105 |
SMART |
|
low complexity region
|
1552 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1685 |
1701 |
N/A |
INTRINSIC |
|
Pfam:CHDCT2
|
1729 |
1901 |
1.7e-99 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000030775
AA Change: S1393G
PolyPhen 2
Score 0.972 (Sensitivity: 0.77; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000030775
Gene: ENSMUSG00000005045
AA Change: S1393G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
46 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
Pfam:CHDNT
|
150 |
203 |
9e-28 |
PFAM |
|
low complexity region
|
209 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
256 |
273 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
323 |
333 |
N/A |
INTRINSIC |
|
PHD
|
347 |
390 |
1.09e-14 |
SMART |
|
RING
|
348 |
389 |
4.48e-1 |
SMART |
|
low complexity region
|
400 |
416 |
N/A |
INTRINSIC |
|
PHD
|
420 |
463 |
3.29e-14 |
SMART |
|
RING
|
421 |
462 |
4.15e0 |
SMART |
|
CHROMO
|
468 |
548 |
2.52e-13 |
SMART |
|
CHROMO
|
592 |
649 |
1.34e-8 |
SMART |
|
low complexity region
|
657 |
678 |
N/A |
INTRINSIC |
|
DEXDc
|
698 |
910 |
8.34e-33 |
SMART |
|
low complexity region
|
1023 |
1038 |
N/A |
INTRINSIC |
|
HELICc
|
1056 |
1140 |
4.02e-26 |
SMART |
|
DUF1087
|
1297 |
1361 |
2.78e-33 |
SMART |
|
DUF1086
|
1374 |
1533 |
5.11e-105 |
SMART |
|
low complexity region
|
1552 |
1567 |
N/A |
INTRINSIC |
|
low complexity region
|
1685 |
1701 |
N/A |
INTRINSIC |
|
Pfam:CHDCT2
|
1730 |
1901 |
2.8e-93 |
PFAM |
|
low complexity region
|
1922 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124423
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000164662
AA Change: S1356G
PolyPhen 2
Score 0.972 (Sensitivity: 0.77; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000132600
Gene: ENSMUSG00000005045
AA Change: S1356G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
46 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
76 |
92 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
Pfam:CHDNT
|
149 |
203 |
1.9e-32 |
PFAM |
|
low complexity region
|
209 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
256 |
273 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
323 |
333 |
N/A |
INTRINSIC |
|
PHD
|
347 |
390 |
1.09e-14 |
SMART |
|
RING
|
348 |
389 |
4.48e-1 |
SMART |
|
low complexity region
|
400 |
416 |
N/A |
INTRINSIC |
|
PHD
|
420 |
463 |
3.29e-14 |
SMART |
|
RING
|
421 |
462 |
4.15e0 |
SMART |
|
CHROMO
|
468 |
548 |
2.52e-13 |
SMART |
|
CHROMO
|
592 |
649 |
1.34e-8 |
SMART |
|
low complexity region
|
657 |
678 |
N/A |
INTRINSIC |
|
DEXDc
|
698 |
910 |
8.34e-33 |
SMART |
|
low complexity region
|
1023 |
1038 |
N/A |
INTRINSIC |
|
HELICc
|
1056 |
1140 |
4.02e-26 |
SMART |
|
DUF1087
|
1260 |
1324 |
2.78e-33 |
SMART |
|
DUF1086
|
1337 |
1496 |
5.11e-105 |
SMART |
|
low complexity region
|
1515 |
1530 |
N/A |
INTRINSIC |
|
low complexity region
|
1648 |
1664 |
N/A |
INTRINSIC |
|
Pfam:CHDCT2
|
1692 |
1864 |
1.7e-99 |
PFAM |
|
low complexity region
|
1885 |
1899 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility with abnormal spermiogenesis and chromatin condensation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5730507C01Rik |
A |
G |
12: 18,583,687 (GRCm39) |
E225G |
possibly damaging |
Het |
| Abcb7 |
T |
C |
X: 103,349,005 (GRCm39) |
M153V |
probably benign |
Het |
| Abi1 |
A |
T |
2: 22,840,276 (GRCm39) |
V329D |
possibly damaging |
Het |
| Ablim3 |
G |
A |
18: 61,982,466 (GRCm39) |
H160Y |
probably benign |
Het |
| Acox3 |
A |
T |
5: 35,766,406 (GRCm39) |
D624V |
possibly damaging |
Het |
| Adam6b |
A |
G |
12: 113,455,442 (GRCm39) |
D753G |
probably benign |
Het |
| Ago1 |
C |
A |
4: 126,333,788 (GRCm39) |
R771L |
probably benign |
Het |
| Aktip |
A |
G |
8: 91,852,505 (GRCm39) |
V217A |
possibly damaging |
Het |
| Ankk1 |
A |
C |
9: 49,327,150 (GRCm39) |
H676Q |
probably benign |
Het |
| Arl1 |
G |
C |
10: 88,569,408 (GRCm39) |
|
probably benign |
Het |
| Asxl3 |
T |
A |
18: 22,650,796 (GRCm39) |
D928E |
probably damaging |
Het |
| AW209491 |
T |
C |
13: 14,811,318 (GRCm39) |
V57A |
possibly damaging |
Het |
| B3galt4 |
G |
T |
17: 34,169,885 (GRCm39) |
Q118K |
probably benign |
Het |
| Ccdc187 |
A |
T |
2: 26,166,080 (GRCm39) |
M783K |
probably benign |
Het |
| Cdon |
T |
G |
9: 35,394,454 (GRCm39) |
M900R |
probably damaging |
Het |
| Ceacam5 |
G |
A |
7: 17,448,835 (GRCm39) |
W67* |
probably null |
Het |
| Chil3 |
C |
T |
3: 106,056,117 (GRCm39) |
|
probably null |
Het |
| Chmp7 |
C |
T |
14: 69,956,899 (GRCm39) |
M336I |
probably benign |
Het |
| Cntn1 |
C |
T |
15: 92,203,021 (GRCm39) |
R768C |
probably damaging |
Het |
| Col6a3 |
T |
A |
1: 90,735,256 (GRCm39) |
I798F |
possibly damaging |
Het |
| Cpxcr1 |
T |
A |
X: 115,387,758 (GRCm39) |
L223* |
probably null |
Het |
| Cpz |
C |
A |
5: 35,659,902 (GRCm39) |
R581L |
possibly damaging |
Het |
| Cxcr2 |
A |
G |
1: 74,198,438 (GRCm39) |
I311V |
probably benign |
Het |
| Cym |
T |
A |
3: 107,126,030 (GRCm39) |
I78F |
probably benign |
Het |
| Defb8 |
A |
T |
8: 19,495,899 (GRCm39) |
S54T |
probably benign |
Het |
| Dennd4a |
A |
G |
9: 64,769,312 (GRCm39) |
T433A |
probably damaging |
Het |
| Dhx29 |
A |
G |
13: 113,084,815 (GRCm39) |
T678A |
probably damaging |
Het |
| Dspp |
T |
C |
5: 104,321,951 (GRCm39) |
|
probably null |
Het |
| Enkur |
G |
T |
2: 21,193,988 (GRCm39) |
A195E |
probably benign |
Het |
| Ero1b |
T |
A |
13: 12,619,292 (GRCm39) |
S429T |
possibly damaging |
Het |
| Fh1 |
A |
G |
1: 175,435,452 (GRCm39) |
S344P |
probably damaging |
Het |
| Flnc |
G |
T |
6: 29,443,478 (GRCm39) |
G553V |
probably damaging |
Het |
| Fmo1 |
A |
T |
1: 162,657,554 (GRCm39) |
L529* |
probably null |
Het |
| Frem1 |
C |
A |
4: 82,868,737 (GRCm39) |
V1415F |
probably damaging |
Het |
| Gatb |
T |
G |
3: 85,526,184 (GRCm39) |
L354R |
probably damaging |
Het |
| Gdpgp1 |
A |
T |
7: 79,888,349 (GRCm39) |
N127Y |
probably damaging |
Het |
| Gpat2 |
A |
G |
2: 127,276,739 (GRCm39) |
T648A |
possibly damaging |
Het |
| Grk6 |
C |
T |
13: 55,599,591 (GRCm39) |
R225* |
probably null |
Het |
| Hells |
A |
T |
19: 38,948,120 (GRCm39) |
Q682L |
probably null |
Het |
| Hspa5 |
T |
A |
2: 34,664,690 (GRCm39) |
N381K |
possibly damaging |
Het |
| Ighmbp2 |
T |
C |
19: 3,312,075 (GRCm39) |
N893S |
probably benign |
Het |
| Ipo11 |
A |
T |
13: 106,948,765 (GRCm39) |
V914E |
possibly damaging |
Het |
| Lars1 |
T |
C |
18: 42,345,673 (GRCm39) |
N1001S |
probably benign |
Het |
| Lats2 |
A |
G |
14: 57,934,912 (GRCm39) |
L606P |
probably damaging |
Het |
| Map4k1 |
T |
C |
7: 28,699,209 (GRCm39) |
Y521H |
probably benign |
Het |
| Marchf11 |
T |
A |
15: 26,387,916 (GRCm39) |
V257E |
probably damaging |
Het |
| Med23 |
G |
A |
10: 24,786,768 (GRCm39) |
|
probably null |
Het |
| Meltf |
A |
G |
16: 31,715,395 (GRCm39) |
D696G |
probably benign |
Het |
| Ms4a7 |
T |
A |
19: 11,301,788 (GRCm39) |
M212L |
probably benign |
Het |
| Mx1 |
A |
T |
16: 97,249,403 (GRCm39) |
L608Q |
probably damaging |
Het |
| Myh1 |
T |
C |
11: 67,095,224 (GRCm39) |
Y195H |
probably damaging |
Het |
| Napb |
G |
T |
2: 148,548,909 (GRCm39) |
H110Q |
probably benign |
Het |
| Ngly1 |
C |
T |
14: 16,260,585 (GRCm38) |
P90S |
probably damaging |
Het |
| Nlrp1b |
T |
A |
11: 71,073,442 (GRCm39) |
I134L |
possibly damaging |
Het |
| Nup210 |
A |
G |
6: 90,993,036 (GRCm39) |
L1017P |
probably damaging |
Het |
| Nup85 |
T |
A |
11: 115,472,643 (GRCm39) |
I233N |
probably damaging |
Het |
| Obsl1 |
A |
G |
1: 75,469,537 (GRCm39) |
V965A |
probably damaging |
Het |
| Or4c12 |
A |
C |
2: 89,774,158 (GRCm39) |
Y100* |
probably null |
Het |
| Or4f6 |
T |
C |
2: 111,839,036 (GRCm39) |
D165G |
probably benign |
Het |
| Or6c5c |
T |
C |
10: 129,299,370 (GRCm39) |
L275P |
probably damaging |
Het |
| Pak1ip1 |
A |
G |
13: 41,164,708 (GRCm39) |
T264A |
possibly damaging |
Het |
| Pard6g |
C |
T |
18: 80,160,357 (GRCm39) |
R157C |
probably damaging |
Het |
| Pcdhb7 |
A |
T |
18: 37,475,631 (GRCm39) |
T256S |
possibly damaging |
Het |
| Phrf1 |
T |
C |
7: 140,820,831 (GRCm39) |
F153L |
probably damaging |
Het |
| Pigw |
A |
T |
11: 84,768,874 (GRCm39) |
F152I |
probably damaging |
Het |
| Pip4k2c |
A |
G |
10: 127,036,744 (GRCm39) |
S222P |
probably damaging |
Het |
| Pjvk |
A |
G |
2: 76,487,775 (GRCm39) |
|
probably null |
Het |
| Plxnd1 |
C |
T |
6: 115,940,875 (GRCm39) |
V1355M |
probably damaging |
Het |
| Pramel26 |
T |
C |
4: 143,539,396 (GRCm39) |
I32M |
probably benign |
Het |
| Prss22 |
G |
A |
17: 24,215,288 (GRCm39) |
P163S |
probably damaging |
Het |
| Prune2 |
A |
G |
19: 17,176,503 (GRCm39) |
I154V |
probably damaging |
Het |
| Rapgef6 |
T |
A |
11: 54,533,637 (GRCm39) |
D362E |
probably benign |
Het |
| Retreg2 |
A |
G |
1: 75,123,319 (GRCm39) |
K416E |
probably benign |
Het |
| Scn7a |
T |
C |
2: 66,510,635 (GRCm39) |
I1256V |
probably benign |
Het |
| Sema4d |
A |
G |
13: 51,865,258 (GRCm39) |
V362A |
possibly damaging |
Het |
| Septin4 |
T |
A |
11: 87,459,741 (GRCm39) |
D496E |
probably damaging |
Het |
| Slc25a34 |
G |
A |
4: 141,349,579 (GRCm39) |
T192I |
probably benign |
Het |
| Tacc3 |
G |
T |
5: 33,825,544 (GRCm39) |
V425L |
probably benign |
Het |
| Tfdp2 |
A |
T |
9: 96,179,762 (GRCm39) |
K125I |
probably damaging |
Het |
| Tjp2 |
C |
T |
19: 24,076,899 (GRCm39) |
R952Q |
possibly damaging |
Het |
| Tk2 |
G |
T |
8: 104,975,077 (GRCm39) |
S30* |
probably null |
Het |
| Tmem74 |
A |
T |
15: 43,730,559 (GRCm39) |
D161E |
probably benign |
Het |
| Tmprss9 |
G |
A |
10: 80,728,119 (GRCm39) |
V570M |
probably damaging |
Het |
| Tnk2 |
C |
A |
16: 32,498,280 (GRCm39) |
P26Q |
probably damaging |
Het |
| Tnpo2 |
T |
G |
8: 85,778,401 (GRCm39) |
V610G |
probably damaging |
Het |
| Trim37 |
T |
C |
11: 87,109,132 (GRCm39) |
F953S |
probably damaging |
Het |
| U2surp |
T |
A |
9: 95,364,150 (GRCm39) |
K589* |
probably null |
Het |
| Usp2 |
G |
A |
9: 43,987,263 (GRCm39) |
R187H |
probably benign |
Het |
| Vmn2r1 |
C |
T |
3: 64,008,926 (GRCm39) |
T535I |
probably benign |
Het |
| Wdr20rt |
T |
A |
12: 65,273,925 (GRCm39) |
S463T |
possibly damaging |
Het |
| Zbtb25 |
C |
A |
12: 76,396,488 (GRCm39) |
G245W |
probably damaging |
Het |
| Zc3h14 |
T |
A |
12: 98,726,613 (GRCm39) |
L27* |
probably null |
Het |
| Zfp2 |
T |
C |
11: 50,791,915 (GRCm39) |
K43E |
probably benign |
Het |
| Zfp268 |
T |
G |
4: 145,350,820 (GRCm39) |
|
probably benign |
Het |
| Zfp654 |
A |
G |
16: 64,605,491 (GRCm39) |
Y904H |
probably benign |
Het |
|
| Other mutations in Chd5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00537:Chd5
|
APN |
4 |
152,445,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00886:Chd5
|
APN |
4 |
152,444,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00963:Chd5
|
APN |
4 |
152,467,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01399:Chd5
|
APN |
4 |
152,441,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01571:Chd5
|
APN |
4 |
152,468,572 (GRCm39) |
splice site |
probably benign |
|
|
IGL01606:Chd5
|
APN |
4 |
152,445,432 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01636:Chd5
|
APN |
4 |
152,469,110 (GRCm39) |
nonsense |
probably null |
|
|
IGL02009:Chd5
|
APN |
4 |
152,450,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02417:Chd5
|
APN |
4 |
152,451,751 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02504:Chd5
|
APN |
4 |
152,447,779 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02508:Chd5
|
APN |
4 |
152,447,481 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Chd5
|
APN |
4 |
152,456,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02608:Chd5
|
APN |
4 |
152,440,564 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02612:Chd5
|
APN |
4 |
152,445,033 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02658:Chd5
|
APN |
4 |
152,445,050 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02662:Chd5
|
APN |
4 |
152,456,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02676:Chd5
|
APN |
4 |
152,440,530 (GRCm39) |
splice site |
probably benign |
|
|
IGL02871:Chd5
|
APN |
4 |
152,461,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02942:Chd5
|
APN |
4 |
152,470,182 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02956:Chd5
|
APN |
4 |
152,464,413 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03286:Chd5
|
APN |
4 |
152,469,952 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03348:Chd5
|
APN |
4 |
152,461,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03398:Chd5
|
APN |
4 |
152,461,539 (GRCm39) |
missense |
probably damaging |
0.97 |
|
PIT1430001:Chd5
|
UTSW |
4 |
152,455,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4151001:Chd5
|
UTSW |
4 |
152,462,986 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0079:Chd5
|
UTSW |
4 |
152,470,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Chd5
|
UTSW |
4 |
152,450,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Chd5
|
UTSW |
4 |
152,450,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0379:Chd5
|
UTSW |
4 |
152,467,778 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0388:Chd5
|
UTSW |
4 |
152,456,101 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0675:Chd5
|
UTSW |
4 |
152,470,407 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0730:Chd5
|
UTSW |
4 |
152,432,441 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0799:Chd5
|
UTSW |
4 |
152,468,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0800:Chd5
|
UTSW |
4 |
152,440,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1276:Chd5
|
UTSW |
4 |
152,463,191 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1752:Chd5
|
UTSW |
4 |
152,459,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1753:Chd5
|
UTSW |
4 |
152,463,272 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Chd5
|
UTSW |
4 |
152,470,263 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1850:Chd5
|
UTSW |
4 |
152,454,990 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1859:Chd5
|
UTSW |
4 |
152,464,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1983:Chd5
|
UTSW |
4 |
152,469,123 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2404:Chd5
|
UTSW |
4 |
152,451,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2897:Chd5
|
UTSW |
4 |
152,456,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2898:Chd5
|
UTSW |
4 |
152,456,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3893:Chd5
|
UTSW |
4 |
152,445,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3938:Chd5
|
UTSW |
4 |
152,461,512 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4707:Chd5
|
UTSW |
4 |
152,445,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4754:Chd5
|
UTSW |
4 |
152,462,203 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4911:Chd5
|
UTSW |
4 |
152,445,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Chd5
|
UTSW |
4 |
152,450,886 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4926:Chd5
|
UTSW |
4 |
152,467,768 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5256:Chd5
|
UTSW |
4 |
152,456,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5524:Chd5
|
UTSW |
4 |
152,461,087 (GRCm39) |
missense |
probably benign |
|
|
R5552:Chd5
|
UTSW |
4 |
152,470,272 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5895:Chd5
|
UTSW |
4 |
152,464,389 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5945:Chd5
|
UTSW |
4 |
152,464,408 (GRCm39) |
missense |
probably benign |
|
|
R6007:Chd5
|
UTSW |
4 |
152,463,878 (GRCm39) |
missense |
probably null |
1.00 |
|
R6039:Chd5
|
UTSW |
4 |
152,438,078 (GRCm39) |
small deletion |
probably benign |
|
|
R6039:Chd5
|
UTSW |
4 |
152,438,078 (GRCm39) |
small deletion |
probably benign |
|
|
R6172:Chd5
|
UTSW |
4 |
152,463,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6173:Chd5
|
UTSW |
4 |
152,463,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6323:Chd5
|
UTSW |
4 |
152,451,791 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6331:Chd5
|
UTSW |
4 |
152,466,865 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6495:Chd5
|
UTSW |
4 |
152,451,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6528:Chd5
|
UTSW |
4 |
152,441,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6849:Chd5
|
UTSW |
4 |
152,462,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6854:Chd5
|
UTSW |
4 |
152,467,395 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6859:Chd5
|
UTSW |
4 |
152,462,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6999:Chd5
|
UTSW |
4 |
152,458,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7034:Chd5
|
UTSW |
4 |
152,445,398 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7110:Chd5
|
UTSW |
4 |
152,469,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7361:Chd5
|
UTSW |
4 |
152,447,745 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7397:Chd5
|
UTSW |
4 |
152,452,469 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7440:Chd5
|
UTSW |
4 |
152,469,108 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7489:Chd5
|
UTSW |
4 |
152,457,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7810:Chd5
|
UTSW |
4 |
152,443,032 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8057:Chd5
|
UTSW |
4 |
152,450,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8078:Chd5
|
UTSW |
4 |
152,445,448 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8092:Chd5
|
UTSW |
4 |
152,463,261 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8170:Chd5
|
UTSW |
4 |
152,461,040 (GRCm39) |
missense |
probably benign |
0.26 |
|
R8255:Chd5
|
UTSW |
4 |
152,463,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8348:Chd5
|
UTSW |
4 |
152,445,173 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8448:Chd5
|
UTSW |
4 |
152,445,173 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8478:Chd5
|
UTSW |
4 |
152,441,147 (GRCm39) |
nonsense |
probably null |
|
|
R8482:Chd5
|
UTSW |
4 |
152,441,147 (GRCm39) |
nonsense |
probably null |
|
|
R8670:Chd5
|
UTSW |
4 |
152,469,953 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8733:Chd5
|
UTSW |
4 |
152,463,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8743:Chd5
|
UTSW |
4 |
152,450,862 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8941:Chd5
|
UTSW |
4 |
152,463,305 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8961:Chd5
|
UTSW |
4 |
152,467,489 (GRCm39) |
splice site |
probably benign |
|
|
R9103:Chd5
|
UTSW |
4 |
152,461,444 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9160:Chd5
|
UTSW |
4 |
152,469,916 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9221:Chd5
|
UTSW |
4 |
152,456,122 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9399:Chd5
|
UTSW |
4 |
152,468,592 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9429:Chd5
|
UTSW |
4 |
152,447,364 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9635:Chd5
|
UTSW |
4 |
152,461,079 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9783:Chd5
|
UTSW |
4 |
152,458,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Chd5
|
UTSW |
4 |
152,462,936 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCATTGACTAGTCTGGGAGGTG -3'
(R):5'- TTAAGCTGCCTCCTGGATTG -3'
Sequencing Primer
(F):5'- ACTAGTCTGGGAGGTGGGGAG -3'
(R):5'- CTCCTAAAGCTCCCATGG -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation