Incidental Mutation 'R1851:Dennd4a'
| ID |
208098 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN/MADD domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
039875-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.432)
|
| Stock # |
R1851 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
64811340-64919667 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 64862030 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 433
(T433A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000038890
AA Change: T433A
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: T433A
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000215025
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 94.9%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 5730507C01Rik |
A |
G |
12: 18,533,686 (GRCm38) |
E225G |
possibly damaging |
Het |
| Abcb7 |
T |
C |
X: 104,305,399 (GRCm38) |
M153V |
probably benign |
Het |
| Abi1 |
A |
T |
2: 22,950,264 (GRCm38) |
V329D |
possibly damaging |
Het |
| Ablim3 |
G |
A |
18: 61,849,395 (GRCm38) |
H160Y |
probably benign |
Het |
| Acox3 |
A |
T |
5: 35,609,062 (GRCm38) |
D624V |
possibly damaging |
Het |
| Adam6b |
A |
G |
12: 113,491,822 (GRCm38) |
D753G |
probably benign |
Het |
| Ago1 |
C |
A |
4: 126,439,995 (GRCm38) |
R771L |
probably benign |
Het |
| Aktip |
A |
G |
8: 91,125,877 (GRCm38) |
V217A |
possibly damaging |
Het |
| Ankk1 |
A |
C |
9: 49,415,850 (GRCm38) |
H676Q |
probably benign |
Het |
| Arl1 |
G |
C |
10: 88,733,546 (GRCm38) |
|
probably benign |
Het |
| Asxl3 |
T |
A |
18: 22,517,739 (GRCm38) |
D928E |
probably damaging |
Het |
| AW209491 |
T |
C |
13: 14,636,733 (GRCm38) |
V57A |
possibly damaging |
Het |
| B3galt4 |
G |
T |
17: 33,950,911 (GRCm38) |
Q118K |
probably benign |
Het |
| Ccdc187 |
A |
T |
2: 26,276,068 (GRCm38) |
M783K |
probably benign |
Het |
| Cdon |
T |
G |
9: 35,483,158 (GRCm38) |
M900R |
probably damaging |
Het |
| Ceacam5 |
G |
A |
7: 17,714,910 (GRCm38) |
W67* |
probably null |
Het |
| Chd5 |
A |
G |
4: 152,378,270 (GRCm38) |
S1356G |
probably damaging |
Het |
| Chil3 |
C |
T |
3: 106,148,801 (GRCm38) |
|
probably null |
Het |
| Chmp7 |
C |
T |
14: 69,719,450 (GRCm38) |
M336I |
probably benign |
Het |
| Cntn1 |
C |
T |
15: 92,305,140 (GRCm38) |
R768C |
probably damaging |
Het |
| Col6a3 |
T |
A |
1: 90,807,534 (GRCm38) |
I798F |
possibly damaging |
Het |
| Cpxcr1 |
T |
A |
X: 116,478,061 (GRCm38) |
L223* |
probably null |
Het |
| Cpz |
C |
A |
5: 35,502,558 (GRCm38) |
R581L |
possibly damaging |
Het |
| Cxcr2 |
A |
G |
1: 74,159,279 (GRCm38) |
I311V |
probably benign |
Het |
| Cym |
T |
A |
3: 107,218,714 (GRCm38) |
I78F |
probably benign |
Het |
| Defb8 |
A |
T |
8: 19,445,883 (GRCm38) |
S54T |
probably benign |
Het |
| Dhx29 |
A |
G |
13: 112,948,281 (GRCm38) |
T678A |
probably damaging |
Het |
| Dspp |
T |
C |
5: 104,174,085 (GRCm38) |
|
probably null |
Het |
| Enkur |
G |
T |
2: 21,189,177 (GRCm38) |
A195E |
probably benign |
Het |
| Ero1lb |
T |
A |
13: 12,604,403 (GRCm38) |
S429T |
possibly damaging |
Het |
| Fh1 |
A |
G |
1: 175,607,886 (GRCm38) |
S344P |
probably damaging |
Het |
| Flnc |
G |
T |
6: 29,443,479 (GRCm38) |
G553V |
probably damaging |
Het |
| Fmo1 |
A |
T |
1: 162,829,985 (GRCm38) |
L529* |
probably null |
Het |
| Frem1 |
C |
A |
4: 82,950,500 (GRCm38) |
V1415F |
probably damaging |
Het |
| Gatb |
T |
G |
3: 85,618,877 (GRCm38) |
L354R |
probably damaging |
Het |
| Gdpgp1 |
A |
T |
7: 80,238,601 (GRCm38) |
N127Y |
probably damaging |
Het |
| Gm11492 |
T |
A |
11: 87,568,915 (GRCm38) |
D496E |
probably damaging |
Het |
| Gm13084 |
T |
C |
4: 143,812,826 (GRCm38) |
I32M |
probably benign |
Het |
| Gm13212 |
T |
G |
4: 145,624,250 (GRCm38) |
|
probably benign |
Het |
| Gpat2 |
A |
G |
2: 127,434,819 (GRCm38) |
T648A |
possibly damaging |
Het |
| Grk6 |
C |
T |
13: 55,451,778 (GRCm38) |
R225* |
probably null |
Het |
| Hells |
A |
T |
19: 38,959,676 (GRCm38) |
Q682L |
probably null |
Het |
| Hspa5 |
T |
A |
2: 34,774,678 (GRCm38) |
N381K |
possibly damaging |
Het |
| Ighmbp2 |
T |
C |
19: 3,262,075 (GRCm38) |
N893S |
probably benign |
Het |
| Ipo11 |
A |
T |
13: 106,812,257 (GRCm38) |
V914E |
possibly damaging |
Het |
| Lars |
T |
C |
18: 42,212,608 (GRCm38) |
N1001S |
probably benign |
Het |
| Lats2 |
A |
G |
14: 57,697,455 (GRCm38) |
L606P |
probably damaging |
Het |
| Map4k1 |
T |
C |
7: 28,999,784 (GRCm38) |
Y521H |
probably benign |
Het |
| March11 |
T |
A |
15: 26,387,830 (GRCm38) |
V257E |
probably damaging |
Het |
| Med23 |
G |
A |
10: 24,910,870 (GRCm38) |
|
probably null |
Het |
| Meltf |
A |
G |
16: 31,896,577 (GRCm38) |
D696G |
probably benign |
Het |
| Ms4a7 |
T |
A |
19: 11,324,424 (GRCm38) |
M212L |
probably benign |
Het |
| Mx1 |
A |
T |
16: 97,448,203 (GRCm38) |
L608Q |
probably damaging |
Het |
| Myh1 |
T |
C |
11: 67,204,398 (GRCm38) |
Y195H |
probably damaging |
Het |
| Napb |
G |
T |
2: 148,706,989 (GRCm38) |
H110Q |
probably benign |
Het |
| Ngly1 |
C |
T |
14: 16,260,585 (GRCm38) |
P90S |
probably damaging |
Het |
| Nlrp1b |
T |
A |
11: 71,182,616 (GRCm38) |
I134L |
possibly damaging |
Het |
| Nup210 |
A |
G |
6: 91,016,054 (GRCm38) |
L1017P |
probably damaging |
Het |
| Nup85 |
T |
A |
11: 115,581,817 (GRCm38) |
I233N |
probably damaging |
Het |
| Obsl1 |
A |
G |
1: 75,492,893 (GRCm38) |
V965A |
probably damaging |
Het |
| Olfr1259 |
A |
C |
2: 89,943,814 (GRCm38) |
Y100* |
probably null |
Het |
| Olfr1310 |
T |
C |
2: 112,008,691 (GRCm38) |
D165G |
probably benign |
Het |
| Olfr787 |
T |
C |
10: 129,463,501 (GRCm38) |
L275P |
probably damaging |
Het |
| Pak1ip1 |
A |
G |
13: 41,011,232 (GRCm38) |
T264A |
possibly damaging |
Het |
| Pard6g |
C |
T |
18: 80,117,142 (GRCm38) |
R157C |
probably damaging |
Het |
| Pcdhb7 |
A |
T |
18: 37,342,578 (GRCm38) |
T256S |
possibly damaging |
Het |
| Phrf1 |
T |
C |
7: 141,240,918 (GRCm38) |
F153L |
probably damaging |
Het |
| Pigw |
A |
T |
11: 84,878,048 (GRCm38) |
F152I |
probably damaging |
Het |
| Pip4k2c |
A |
G |
10: 127,200,875 (GRCm38) |
S222P |
probably damaging |
Het |
| Pjvk |
A |
G |
2: 76,657,431 (GRCm38) |
|
probably null |
Het |
| Plxnd1 |
C |
T |
6: 115,963,914 (GRCm38) |
V1355M |
probably damaging |
Het |
| Prss22 |
G |
A |
17: 23,996,314 (GRCm38) |
P163S |
probably damaging |
Het |
| Prune2 |
A |
G |
19: 17,199,139 (GRCm38) |
I154V |
probably damaging |
Het |
| Rapgef6 |
T |
A |
11: 54,642,811 (GRCm38) |
D362E |
probably benign |
Het |
| Retreg2 |
A |
G |
1: 75,146,675 (GRCm38) |
K416E |
probably benign |
Het |
| Scn7a |
T |
C |
2: 66,680,291 (GRCm38) |
I1256V |
probably benign |
Het |
| Sema4d |
A |
G |
13: 51,711,222 (GRCm38) |
V362A |
possibly damaging |
Het |
| Slc25a34 |
G |
A |
4: 141,622,268 (GRCm38) |
T192I |
probably benign |
Het |
| Tacc3 |
G |
T |
5: 33,668,200 (GRCm38) |
V425L |
probably benign |
Het |
| Tfdp2 |
A |
T |
9: 96,297,709 (GRCm38) |
K125I |
probably damaging |
Het |
| Tjp2 |
C |
T |
19: 24,099,535 (GRCm38) |
R952Q |
possibly damaging |
Het |
| Tk2 |
G |
T |
8: 104,248,445 (GRCm38) |
S30* |
probably null |
Het |
| Tmem74 |
A |
T |
15: 43,867,163 (GRCm38) |
D161E |
probably benign |
Het |
| Tmprss9 |
G |
A |
10: 80,892,285 (GRCm38) |
V570M |
probably damaging |
Het |
| Tnk2 |
C |
A |
16: 32,679,462 (GRCm38) |
P26Q |
probably damaging |
Het |
| Tnpo2 |
T |
G |
8: 85,051,772 (GRCm38) |
V610G |
probably damaging |
Het |
| Trim37 |
T |
C |
11: 87,218,306 (GRCm38) |
F953S |
probably damaging |
Het |
| U2surp |
T |
A |
9: 95,482,097 (GRCm38) |
K589* |
probably null |
Het |
| Usp2 |
G |
A |
9: 44,075,966 (GRCm38) |
R187H |
probably benign |
Het |
| Vmn2r1 |
C |
T |
3: 64,101,505 (GRCm38) |
T535I |
probably benign |
Het |
| Wdr20rt |
T |
A |
12: 65,227,151 (GRCm38) |
S463T |
possibly damaging |
Het |
| Zbtb25 |
C |
A |
12: 76,349,714 (GRCm38) |
G245W |
probably damaging |
Het |
| Zc3h14 |
T |
A |
12: 98,760,354 (GRCm38) |
L27* |
probably null |
Het |
| Zfp2 |
T |
C |
11: 50,901,088 (GRCm38) |
K43E |
probably benign |
Het |
| Zfp654 |
A |
G |
16: 64,785,128 (GRCm38) |
Y904H |
probably benign |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,911,762 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,906,884 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,842,621 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,894,409 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,909,706 (GRCm38) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,842,561 (GRCm38) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,851,298 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,862,327 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,910,191 (GRCm38) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,897,353 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,862,414 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,871,874 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,888,526 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,888,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,896,715 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,893,294 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,852,445 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,862,391 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,851,383 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,911,675 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,910,004 (GRCm38) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,906,045 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,911,665 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,871,882 (GRCm38) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,859,358 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1870:Dennd4a
|
UTSW |
9 |
64,897,234 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,897,336 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,889,086 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,842,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,852,467 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,889,605 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,905,974 (GRCm38) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,889,337 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,852,417 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,906,081 (GRCm38) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,912,387 (GRCm38) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,888,993 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,872,028 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,852,575 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,862,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,911,892 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,910,123 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,894,407 (GRCm38) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,897,357 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,897,249 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,889,056 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4876:Dennd4a
|
UTSW |
9 |
64,896,590 (GRCm38) |
missense |
probably benign |
|
|
R4881:Dennd4a
|
UTSW |
9 |
64,838,844 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,906,003 (GRCm38) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,888,928 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,904,227 (GRCm38) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,851,209 (GRCm38) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,896,729 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,911,755 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,886,945 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,871,899 (GRCm38) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,852,420 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,886,965 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,852,489 (GRCm38) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,906,923 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,894,399 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,896,474 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,861,956 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,897,269 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,852,570 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,873,044 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,888,587 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,852,431 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,906,920 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,872,993 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,852,512 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,873,030 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,888,568 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,849,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,906,875 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,889,109 (GRCm38) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,838,974 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,886,879 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,912,390 (GRCm38) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,889,094 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,842,624 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,912,692 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,907,106 (GRCm38) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,893,358 (GRCm38) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,894,511 (GRCm38) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,897,320 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,872,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATATGCACAACCCTGCTCTCTTAG -3'
(R):5'- CGAAGCATAAGTTATCAGCATAGAC -3'
Sequencing Primer
(F):5'- CCCTGCTCTCTTAGATAATTAGGAG -3'
(R):5'- CTGCTTCAACAATGTATAAATCC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation