Incidental Mutation 'R1853:Pds5a'
| ID |
208316 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pds5a
|
| Ensembl Gene |
ENSMUSG00000029202 |
| Gene Name |
PDS5 cohesin associated factor A |
| Synonyms |
9030416H16Rik, E230024D05Rik |
| MMRRC Submission |
039877-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1853 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
65763062-65855579 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 65781372 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1036
(V1036A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144171
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031104]
[ENSMUST00000201948]
[ENSMUST00000202648]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000031104
AA Change: V1036A
PolyPhen 2
Score 0.556 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000031104
Gene: ENSMUSG00000029202
AA Change: V1036A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
253 |
782 |
6e-30 |
SMART |
|
low complexity region
|
934 |
946 |
N/A |
INTRINSIC |
|
low complexity region
|
1174 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200766
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201420
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201770
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000201948
AA Change: V1036A
PolyPhen 2
Score 0.556 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000144171
Gene: ENSMUSG00000029202
AA Change: V1036A
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
253 |
782 |
6e-30 |
SMART |
|
low complexity region
|
934 |
946 |
N/A |
INTRINSIC |
|
low complexity region
|
1174 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201987
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202107
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202446
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202910
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000202648
|
| SMART Domains |
Protein: ENSMUSP00000144463
Gene: ENSMUSG00000029202
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
58 |
74 |
N/A |
INTRINSIC |
|
low complexity region
|
100 |
110 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality associated with respiratory distress, abnormal heart development, abnormal skeletal development, kidney agenesis, and delayed enteric nervous system development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acadvl |
T |
C |
11: 69,901,696 (GRCm39) |
K554E |
probably damaging |
Het |
| Acap2 |
C |
T |
16: 30,936,122 (GRCm39) |
E322K |
probably damaging |
Het |
| Adam32 |
T |
C |
8: 25,388,642 (GRCm39) |
Y354C |
probably benign |
Het |
| Agl |
A |
T |
3: 116,572,971 (GRCm39) |
Y789* |
probably null |
Het |
| Aida |
A |
G |
1: 183,087,380 (GRCm39) |
T68A |
probably benign |
Het |
| Aldh3b3 |
T |
A |
19: 4,015,822 (GRCm39) |
L264Q |
probably damaging |
Het |
| Anks6 |
T |
C |
4: 47,049,387 (GRCm39) |
T173A |
probably benign |
Het |
| Ankzf1 |
A |
G |
1: 75,174,772 (GRCm39) |
|
probably null |
Het |
| Apob |
A |
T |
12: 8,060,928 (GRCm39) |
K3137* |
probably null |
Het |
| Arhgef16 |
C |
T |
4: 154,375,563 (GRCm39) |
V144I |
probably benign |
Het |
| Arhgef2 |
A |
T |
3: 88,540,222 (GRCm39) |
T107S |
possibly damaging |
Het |
| Ark2c |
T |
A |
18: 77,550,671 (GRCm39) |
S279C |
possibly damaging |
Het |
| Atad2 |
G |
A |
15: 57,960,685 (GRCm39) |
P971L |
possibly damaging |
Het |
| Atp6ap1l |
T |
C |
13: 91,031,707 (GRCm39) |
E325G |
probably damaging |
Het |
| BC035947 |
T |
C |
1: 78,475,653 (GRCm39) |
N293S |
possibly damaging |
Het |
| Bhmt |
C |
T |
13: 93,761,843 (GRCm39) |
V147M |
probably damaging |
Het |
| Ccdc112 |
A |
T |
18: 46,418,767 (GRCm39) |
H447Q |
probably benign |
Het |
| Cd274 |
T |
A |
19: 29,357,882 (GRCm39) |
N191K |
probably damaging |
Het |
| Ckmt1 |
C |
T |
2: 121,191,131 (GRCm39) |
T181I |
probably damaging |
Het |
| Cnih3 |
C |
A |
1: 181,282,186 (GRCm39) |
S140* |
probably null |
Het |
| Col28a1 |
T |
G |
6: 8,014,574 (GRCm39) |
I944L |
probably benign |
Het |
| Cttnbp2 |
T |
C |
6: 18,408,601 (GRCm39) |
T1007A |
probably benign |
Het |
| Cux2 |
G |
T |
5: 122,007,184 (GRCm39) |
P826T |
possibly damaging |
Het |
| Cyren |
A |
G |
6: 34,852,494 (GRCm39) |
V67A |
probably damaging |
Het |
| Dap3 |
A |
T |
3: 88,838,233 (GRCm39) |
V86E |
probably damaging |
Het |
| Ddah1 |
A |
G |
3: 145,597,304 (GRCm39) |
I180M |
probably benign |
Het |
| Ddt |
T |
C |
10: 75,609,138 (GRCm39) |
E7G |
possibly damaging |
Het |
| Dhx57 |
A |
T |
17: 80,582,308 (GRCm39) |
Y432* |
probably null |
Het |
| Dpp9 |
T |
C |
17: 56,509,885 (GRCm39) |
I314V |
probably benign |
Het |
| Enpp2 |
C |
T |
15: 54,709,219 (GRCm39) |
E803K |
probably damaging |
Het |
| Ercc6 |
T |
A |
14: 32,298,773 (GRCm39) |
I1387N |
possibly damaging |
Het |
| Fancg |
T |
C |
4: 43,009,727 (GRCm39) |
E57G |
probably benign |
Het |
| Fcgbpl1 |
C |
T |
7: 27,854,971 (GRCm39) |
Q1866* |
probably null |
Het |
| Fkbp5 |
A |
T |
17: 28,648,281 (GRCm39) |
C103S |
possibly damaging |
Het |
| Gm14403 |
C |
A |
2: 177,200,932 (GRCm39) |
H293N |
probably damaging |
Het |
| Gm4353 |
G |
A |
7: 115,682,804 (GRCm39) |
P259L |
probably benign |
Het |
| Gm4787 |
T |
A |
12: 81,425,108 (GRCm39) |
H350L |
probably damaging |
Het |
| Hibch |
T |
C |
1: 52,940,494 (GRCm39) |
|
probably null |
Het |
| Impg2 |
T |
C |
16: 56,080,640 (GRCm39) |
S815P |
probably damaging |
Het |
| Ipo11 |
A |
T |
13: 106,997,395 (GRCm39) |
I688K |
probably benign |
Het |
| Kcnd3 |
A |
T |
3: 105,367,068 (GRCm39) |
T313S |
probably damaging |
Het |
| Kctd14 |
A |
T |
7: 97,102,631 (GRCm39) |
S38C |
possibly damaging |
Het |
| Kdm3b |
G |
T |
18: 34,966,446 (GRCm39) |
R1660L |
probably damaging |
Het |
| Kdr |
C |
T |
5: 76,113,565 (GRCm39) |
G768S |
possibly damaging |
Het |
| Klhl2 |
G |
A |
8: 65,275,658 (GRCm39) |
H82Y |
probably benign |
Het |
| Lama3 |
A |
T |
18: 12,646,762 (GRCm39) |
T1759S |
possibly damaging |
Het |
| Lamb1 |
T |
G |
12: 31,368,271 (GRCm39) |
C1134G |
probably damaging |
Het |
| Macf1 |
T |
C |
4: 123,406,513 (GRCm39) |
|
probably null |
Het |
| Mlph |
C |
T |
1: 90,873,389 (GRCm39) |
Q567* |
probably null |
Het |
| Mocos |
A |
C |
18: 24,829,026 (GRCm39) |
E777A |
probably damaging |
Het |
| Neil1 |
T |
A |
9: 57,051,999 (GRCm39) |
Q214L |
probably damaging |
Het |
| Nes |
A |
G |
3: 87,883,114 (GRCm39) |
T458A |
possibly damaging |
Het |
| Nlgn1 |
A |
T |
3: 26,187,671 (GRCm39) |
N71K |
possibly damaging |
Het |
| Nr4a1 |
T |
C |
15: 101,169,645 (GRCm39) |
I305T |
probably benign |
Het |
| Nup58 |
T |
C |
14: 60,481,996 (GRCm39) |
T123A |
possibly damaging |
Het |
| Oas1c |
A |
T |
5: 120,946,060 (GRCm39) |
V146E |
probably damaging |
Het |
| Oit3 |
C |
T |
10: 59,277,444 (GRCm39) |
|
probably null |
Het |
| Or12k8 |
A |
T |
2: 36,975,232 (GRCm39) |
F176Y |
probably damaging |
Het |
| Or4k15c |
A |
G |
14: 50,321,577 (GRCm39) |
L187P |
probably damaging |
Het |
| Osbp |
T |
C |
19: 11,951,255 (GRCm39) |
S267P |
possibly damaging |
Het |
| Pclo |
T |
A |
5: 14,726,698 (GRCm39) |
|
probably benign |
Het |
| Pde9a |
C |
T |
17: 31,674,094 (GRCm39) |
P60S |
probably damaging |
Het |
| Pdia3 |
T |
C |
2: 121,262,144 (GRCm39) |
I205T |
probably benign |
Het |
| Pdia4 |
A |
T |
6: 47,790,161 (GRCm39) |
D26E |
unknown |
Het |
| Pitx3 |
C |
T |
19: 46,125,912 (GRCm39) |
G4R |
probably benign |
Het |
| Pnn |
T |
A |
12: 59,118,399 (GRCm39) |
N327K |
probably damaging |
Het |
| Pole |
T |
G |
5: 110,454,719 (GRCm39) |
I984R |
possibly damaging |
Het |
| Psme2 |
T |
A |
14: 55,825,936 (GRCm39) |
I124F |
probably damaging |
Het |
| Pstpip2 |
T |
A |
18: 77,959,499 (GRCm39) |
L198Q |
probably damaging |
Het |
| Siglece |
A |
G |
7: 43,309,360 (GRCm39) |
F66S |
probably benign |
Het |
| Slc1a6 |
T |
A |
10: 78,648,758 (GRCm39) |
V493E |
probably damaging |
Het |
| Snd1 |
T |
A |
6: 28,545,563 (GRCm39) |
I373N |
probably damaging |
Het |
| Srrm2 |
A |
G |
17: 24,039,499 (GRCm39) |
T2144A |
probably damaging |
Het |
| Sst |
A |
G |
16: 23,709,403 (GRCm39) |
L31P |
probably damaging |
Het |
| Stab1 |
C |
T |
14: 30,862,420 (GRCm39) |
V2305M |
probably damaging |
Het |
| Stard9 |
T |
C |
2: 120,519,232 (GRCm39) |
I545T |
probably damaging |
Het |
| Tcaim |
T |
C |
9: 122,655,271 (GRCm39) |
W248R |
probably damaging |
Het |
| Tepsin |
A |
C |
11: 119,989,462 (GRCm39) |
F13C |
probably damaging |
Het |
| Terf1 |
T |
A |
1: 15,889,162 (GRCm39) |
L197* |
probably null |
Het |
| Tiam2 |
C |
T |
17: 3,465,410 (GRCm39) |
R380C |
probably damaging |
Het |
| Tmem63b |
G |
A |
17: 45,972,223 (GRCm39) |
H745Y |
possibly damaging |
Het |
| Trim40 |
A |
G |
17: 37,199,970 (GRCm39) |
L36P |
probably damaging |
Het |
| Trim72 |
A |
G |
7: 127,608,254 (GRCm39) |
I251V |
probably benign |
Het |
| Trio |
T |
C |
15: 27,756,622 (GRCm39) |
Y914C |
probably damaging |
Het |
| Vmn2r113 |
G |
A |
17: 23,164,501 (GRCm39) |
V135I |
probably benign |
Het |
| Vmn2r117 |
T |
A |
17: 23,696,429 (GRCm39) |
H326L |
probably damaging |
Het |
| Vmn2r28 |
A |
T |
7: 5,484,246 (GRCm39) |
C651* |
probably null |
Het |
| Xpnpep1 |
T |
C |
19: 52,994,641 (GRCm39) |
E329G |
probably benign |
Het |
| Xpo4 |
G |
A |
14: 57,823,364 (GRCm39) |
T1042M |
possibly damaging |
Het |
| Ypel1 |
A |
C |
16: 16,925,087 (GRCm39) |
D28E |
probably benign |
Het |
| Zdbf2 |
GAAAAA |
GAAAAAA |
1: 63,344,701 (GRCm39) |
|
probably null |
Het |
| Zfp51 |
A |
T |
17: 21,684,585 (GRCm39) |
H400L |
probably damaging |
Het |
| Zfp518b |
A |
T |
5: 38,830,750 (GRCm39) |
F418L |
probably benign |
Het |
| Zfp54 |
T |
A |
17: 21,654,404 (GRCm39) |
Y299* |
probably null |
Het |
| Zfp672 |
T |
C |
11: 58,207,790 (GRCm39) |
H177R |
probably benign |
Het |
| Zfp692 |
C |
A |
11: 58,200,805 (GRCm39) |
P229T |
possibly damaging |
Het |
| Zswim4 |
A |
T |
8: 84,950,829 (GRCm39) |
C533S |
probably damaging |
Het |
|
| Other mutations in Pds5a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00589:Pds5a
|
APN |
5 |
65,813,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00979:Pds5a
|
APN |
5 |
65,789,066 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01314:Pds5a
|
APN |
5 |
65,772,637 (GRCm39) |
missense |
probably benign |
|
|
IGL02449:Pds5a
|
APN |
5 |
65,776,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02539:Pds5a
|
APN |
5 |
65,823,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03395:Pds5a
|
APN |
5 |
65,809,792 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R0569:Pds5a
|
UTSW |
5 |
65,813,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0704:Pds5a
|
UTSW |
5 |
65,777,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1170:Pds5a
|
UTSW |
5 |
65,792,645 (GRCm39) |
splice site |
probably benign |
|
|
R1181:Pds5a
|
UTSW |
5 |
65,784,545 (GRCm39) |
splice site |
probably null |
|
|
R1193:Pds5a
|
UTSW |
5 |
65,795,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1537:Pds5a
|
UTSW |
5 |
65,804,464 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2016:Pds5a
|
UTSW |
5 |
65,805,350 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R2154:Pds5a
|
UTSW |
5 |
65,807,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2209:Pds5a
|
UTSW |
5 |
65,785,357 (GRCm39) |
nonsense |
probably null |
|
|
R2234:Pds5a
|
UTSW |
5 |
65,811,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2235:Pds5a
|
UTSW |
5 |
65,811,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2332:Pds5a
|
UTSW |
5 |
65,784,422 (GRCm39) |
splice site |
probably null |
|
|
R3114:Pds5a
|
UTSW |
5 |
65,776,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3417:Pds5a
|
UTSW |
5 |
65,795,235 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3820:Pds5a
|
UTSW |
5 |
65,811,419 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4152:Pds5a
|
UTSW |
5 |
65,823,514 (GRCm39) |
nonsense |
probably null |
|
|
R4159:Pds5a
|
UTSW |
5 |
65,821,839 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4160:Pds5a
|
UTSW |
5 |
65,821,839 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4161:Pds5a
|
UTSW |
5 |
65,821,839 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4230:Pds5a
|
UTSW |
5 |
65,787,329 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4491:Pds5a
|
UTSW |
5 |
65,792,780 (GRCm39) |
missense |
probably benign |
|
|
R4647:Pds5a
|
UTSW |
5 |
65,813,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4816:Pds5a
|
UTSW |
5 |
65,808,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4867:Pds5a
|
UTSW |
5 |
65,801,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5001:Pds5a
|
UTSW |
5 |
65,854,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5013:Pds5a
|
UTSW |
5 |
65,792,680 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5054:Pds5a
|
UTSW |
5 |
65,795,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5068:Pds5a
|
UTSW |
5 |
65,772,615 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5178:Pds5a
|
UTSW |
5 |
65,821,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5269:Pds5a
|
UTSW |
5 |
65,821,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5396:Pds5a
|
UTSW |
5 |
65,795,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5704:Pds5a
|
UTSW |
5 |
65,784,422 (GRCm39) |
splice site |
probably null |
|
|
R5940:Pds5a
|
UTSW |
5 |
65,801,328 (GRCm39) |
intron |
probably benign |
|
|
R6306:Pds5a
|
UTSW |
5 |
65,813,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6322:Pds5a
|
UTSW |
5 |
65,854,177 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6467:Pds5a
|
UTSW |
5 |
65,809,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6476:Pds5a
|
UTSW |
5 |
65,791,630 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6513:Pds5a
|
UTSW |
5 |
65,772,944 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7304:Pds5a
|
UTSW |
5 |
65,777,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7312:Pds5a
|
UTSW |
5 |
65,823,570 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7438:Pds5a
|
UTSW |
5 |
65,809,878 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7637:Pds5a
|
UTSW |
5 |
65,795,947 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7654:Pds5a
|
UTSW |
5 |
65,776,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7707:Pds5a
|
UTSW |
5 |
65,767,476 (GRCm39) |
missense |
unknown |
|
|
R7715:Pds5a
|
UTSW |
5 |
65,795,904 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7748:Pds5a
|
UTSW |
5 |
65,777,009 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7910:Pds5a
|
UTSW |
5 |
65,795,925 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8014:Pds5a
|
UTSW |
5 |
65,785,082 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R8023:Pds5a
|
UTSW |
5 |
65,795,241 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Pds5a
|
UTSW |
5 |
65,809,741 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8190:Pds5a
|
UTSW |
5 |
65,781,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8406:Pds5a
|
UTSW |
5 |
65,803,681 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9074:Pds5a
|
UTSW |
5 |
65,804,479 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9222:Pds5a
|
UTSW |
5 |
65,805,281 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9390:Pds5a
|
UTSW |
5 |
65,823,600 (GRCm39) |
missense |
probably benign |
0.39 |
|
R9404:Pds5a
|
UTSW |
5 |
65,776,307 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9479:Pds5a
|
UTSW |
5 |
65,792,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9493:Pds5a
|
UTSW |
5 |
65,792,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9596:Pds5a
|
UTSW |
5 |
65,772,830 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9681:Pds5a
|
UTSW |
5 |
65,808,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9688:Pds5a
|
UTSW |
5 |
65,812,196 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9792:Pds5a
|
UTSW |
5 |
65,795,989 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Pds5a
|
UTSW |
5 |
65,776,329 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Pds5a
|
UTSW |
5 |
65,817,070 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
Z1177:Pds5a
|
UTSW |
5 |
65,808,555 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTATGATATACTTGTGGAGGAAAAGC -3'
(R):5'- TGTAAATCATTCTGGGAACTGGAC -3'
Sequencing Primer
(F):5'- AAAAGCGCGGGTTGGTGTATTC -3'
(R):5'- CACAATGAGCCAGCTTGTGTTAC -3'
|
| Posted On |
2014-06-23 |
Incidental Mutation