Incidental Mutation 'R1883:Cntn4'
| ID |
209254 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cntn4
|
| Ensembl Gene |
ENSMUSG00000064293 |
| Gene Name |
contactin 4 |
| Synonyms |
BIG-2A, Axcam |
| MMRRC Submission |
039904-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.318)
|
| Stock # |
R1883 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
105654621-106676271 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 106656353 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 885
(T885A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108889
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089208]
[ENSMUST00000113264]
|
| AlphaFold |
Q69Z26 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089208
AA Change: T885A
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000086616
Gene: ENSMUSG00000064293
AA Change: T885A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
IGc2
|
41 |
107 |
2.32e-8 |
SMART |
|
IG
|
129 |
215 |
3.4e-6 |
SMART |
|
IGc2
|
238 |
302 |
8.76e-18 |
SMART |
|
IGc2
|
328 |
391 |
2.91e-14 |
SMART |
|
IGc2
|
420 |
484 |
1.58e-10 |
SMART |
|
IG
|
504 |
594 |
9.55e-10 |
SMART |
|
FN3
|
597 |
683 |
1.54e-11 |
SMART |
|
FN3
|
700 |
786 |
8.39e0 |
SMART |
|
FN3
|
801 |
886 |
1.33e-6 |
SMART |
|
FN3
|
901 |
981 |
9.85e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113264
AA Change: T885A
PolyPhen 2
Score 0.009 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000108889
Gene: ENSMUSG00000064293
AA Change: T885A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
18 |
N/A |
INTRINSIC |
|
IGc2
|
41 |
107 |
2.32e-8 |
SMART |
|
IG
|
129 |
215 |
3.4e-6 |
SMART |
|
IGc2
|
238 |
302 |
8.76e-18 |
SMART |
|
IGc2
|
328 |
391 |
2.91e-14 |
SMART |
|
IGc2
|
420 |
484 |
1.58e-10 |
SMART |
|
IG
|
504 |
594 |
9.55e-10 |
SMART |
|
FN3
|
597 |
683 |
1.54e-11 |
SMART |
|
FN3
|
700 |
786 |
8.39e0 |
SMART |
|
FN3
|
801 |
886 |
1.33e-6 |
SMART |
|
FN3
|
901 |
981 |
9.85e-1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123596
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132395
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204621
|
| Meta Mutation Damage Score |
0.0617 |
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the contactin family of immunoglobulins. Contactins are axon-associated cell adhesion molecules that function in neuronal network formation and plasticity. The encoded protein is a glycosylphosphatidylinositol-anchored neuronal membrane protein that may play a role in the formation of axon connections in the developing nervous system. Deletion or mutation of this gene may play a role in 3p deletion syndrome and autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit aberrant projection of olfactory axons to multiple glomeruli in the olfactory bulb. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ano9 |
T |
C |
7: 140,682,244 (GRCm39) |
E677G |
probably benign |
Het |
| Auh |
G |
A |
13: 52,989,532 (GRCm39) |
P308L |
probably benign |
Het |
| Bhmt1b |
T |
C |
18: 87,774,669 (GRCm39) |
L64P |
probably damaging |
Het |
| Brs3 |
T |
C |
X: 56,092,449 (GRCm39) |
I311T |
probably benign |
Het |
| Capn9 |
A |
G |
8: 125,338,297 (GRCm39) |
K552R |
probably benign |
Het |
| Catsperg1 |
C |
T |
7: 28,881,661 (GRCm39) |
|
probably null |
Het |
| Cdc16 |
A |
G |
8: 13,825,738 (GRCm39) |
N449D |
probably damaging |
Het |
| Cdyl2 |
A |
T |
8: 117,321,902 (GRCm39) |
N208K |
probably damaging |
Het |
| Cnot4 |
C |
T |
6: 35,055,092 (GRCm39) |
V66I |
probably damaging |
Het |
| Col20a1 |
C |
T |
2: 180,634,703 (GRCm39) |
T131I |
possibly damaging |
Het |
| Crybg2 |
C |
A |
4: 133,801,594 (GRCm39) |
S918* |
probably null |
Het |
| Dact2 |
A |
T |
17: 14,418,085 (GRCm39) |
S207T |
possibly damaging |
Het |
| Dbnl |
G |
A |
11: 5,749,247 (GRCm39) |
G356E |
probably benign |
Het |
| Ddx18 |
C |
A |
1: 121,495,645 (GRCm39) |
|
probably benign |
Het |
| Dis3 |
A |
T |
14: 99,328,905 (GRCm39) |
H282Q |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,677,142 (GRCm39) |
D453G |
probably benign |
Het |
| Dst |
T |
C |
1: 34,228,389 (GRCm39) |
V1994A |
possibly damaging |
Het |
| Dusp8 |
C |
T |
7: 141,638,085 (GRCm39) |
|
probably null |
Het |
| Eipr1 |
A |
T |
12: 28,816,850 (GRCm39) |
H69L |
possibly damaging |
Het |
| Eml1 |
A |
G |
12: 108,429,911 (GRCm39) |
R65G |
probably damaging |
Het |
| Epha7 |
C |
T |
4: 28,950,362 (GRCm39) |
H722Y |
possibly damaging |
Het |
| Epyc |
A |
T |
10: 97,511,695 (GRCm39) |
K229N |
possibly damaging |
Het |
| Extl1 |
A |
G |
4: 134,091,917 (GRCm39) |
I312T |
probably benign |
Het |
| F13a1 |
G |
C |
13: 37,172,981 (GRCm39) |
A133G |
probably benign |
Het |
| Fam185a |
G |
T |
5: 21,630,242 (GRCm39) |
C26F |
possibly damaging |
Het |
| Fam186b |
T |
C |
15: 99,176,679 (GRCm39) |
N737S |
probably damaging |
Het |
| Fam78b |
A |
G |
1: 166,829,171 (GRCm39) |
I13V |
probably benign |
Het |
| Fat1 |
A |
T |
8: 45,504,184 (GRCm39) |
Q4559L |
probably benign |
Het |
| Fnip1 |
T |
C |
11: 54,406,373 (GRCm39) |
S1157P |
probably damaging |
Het |
| Foxj3 |
A |
C |
4: 119,467,226 (GRCm39) |
M190L |
probably benign |
Het |
| Heatr3 |
T |
C |
8: 88,871,221 (GRCm39) |
Y192H |
possibly damaging |
Het |
| Hexd |
T |
A |
11: 121,098,524 (GRCm39) |
S3T |
probably benign |
Het |
| Klf3 |
C |
T |
5: 64,980,224 (GRCm39) |
P5S |
probably damaging |
Het |
| Klf9 |
C |
T |
19: 23,142,101 (GRCm39) |
S187L |
probably damaging |
Het |
| Krt9 |
T |
C |
11: 100,079,523 (GRCm39) |
H623R |
unknown |
Het |
| Krtap2-4 |
G |
C |
11: 99,505,505 (GRCm39) |
|
probably benign |
Het |
| Lmtk3 |
T |
C |
7: 45,436,273 (GRCm39) |
Y84H |
probably damaging |
Het |
| Mroh3 |
G |
T |
1: 136,134,731 (GRCm39) |
A166D |
probably damaging |
Het |
| Musk |
C |
A |
4: 58,373,189 (GRCm39) |
P697T |
probably benign |
Het |
| Nek9 |
A |
G |
12: 85,379,330 (GRCm39) |
L192P |
probably damaging |
Het |
| Nipbl |
A |
C |
15: 8,356,616 (GRCm39) |
F1590C |
probably damaging |
Het |
| Nrk |
G |
T |
X: 137,907,922 (GRCm39) |
V1455F |
probably damaging |
Het |
| Nsun3 |
T |
C |
16: 62,555,656 (GRCm39) |
D290G |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,969,029 (GRCm39) |
T222A |
probably damaging |
Het |
| Or2a12 |
T |
C |
6: 42,904,764 (GRCm39) |
S200P |
probably damaging |
Het |
| Or51f1d |
T |
C |
7: 102,701,189 (GRCm39) |
I228T |
probably benign |
Het |
| Or6b9 |
T |
C |
7: 106,555,981 (GRCm39) |
H54R |
probably benign |
Het |
| Osbpl11 |
T |
G |
16: 33,034,723 (GRCm39) |
H237Q |
probably benign |
Het |
| Pde10a |
A |
T |
17: 9,197,776 (GRCm39) |
T671S |
possibly damaging |
Het |
| Pkd2 |
A |
T |
5: 104,631,094 (GRCm39) |
N506I |
probably damaging |
Het |
| Ppp3cb |
A |
G |
14: 20,573,913 (GRCm39) |
V274A |
possibly damaging |
Het |
| Prex1 |
T |
C |
2: 166,425,192 (GRCm39) |
D938G |
probably benign |
Het |
| Ptch1 |
G |
A |
13: 63,659,841 (GRCm39) |
Q1134* |
probably null |
Het |
| Rasgrf2 |
A |
G |
13: 92,117,149 (GRCm39) |
V820A |
probably benign |
Het |
| Rimbp2 |
C |
T |
5: 128,880,998 (GRCm39) |
V137M |
possibly damaging |
Het |
| Rpa1 |
A |
G |
11: 75,209,309 (GRCm39) |
V137A |
probably benign |
Het |
| Rps6ka1 |
A |
C |
4: 133,591,354 (GRCm39) |
I299S |
probably damaging |
Het |
| Scn3b |
A |
C |
9: 40,190,669 (GRCm39) |
|
probably null |
Het |
| Sdha |
A |
T |
13: 74,481,255 (GRCm39) |
I317N |
probably damaging |
Het |
| Serpina1d |
T |
A |
12: 103,732,037 (GRCm39) |
D274V |
possibly damaging |
Het |
| Sik3 |
C |
G |
9: 46,132,387 (GRCm39) |
H1276Q |
probably benign |
Het |
| Snx14 |
T |
A |
9: 88,284,314 (GRCm39) |
E451D |
probably benign |
Het |
| Spmip4 |
T |
C |
6: 50,551,433 (GRCm39) |
T339A |
probably benign |
Het |
| Swt1 |
T |
A |
1: 151,299,284 (GRCm39) |
K8* |
probably null |
Het |
| Tas1r3 |
G |
T |
4: 155,946,610 (GRCm39) |
P332T |
probably damaging |
Het |
| Tas2r126 |
A |
T |
6: 42,411,961 (GRCm39) |
T165S |
probably benign |
Het |
| Tecpr1 |
A |
G |
5: 144,143,347 (GRCm39) |
V676A |
probably benign |
Het |
| Tg |
A |
G |
15: 66,543,158 (GRCm39) |
E24G |
probably damaging |
Het |
| Tlr7 |
C |
T |
X: 166,089,468 (GRCm39) |
G673S |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,908,539 (GRCm39) |
D1520E |
probably benign |
Het |
| Trabd |
A |
G |
15: 88,966,184 (GRCm39) |
E47G |
probably damaging |
Het |
| Trim29 |
T |
A |
9: 43,222,702 (GRCm39) |
I177N |
probably damaging |
Het |
| Ubxn2a |
A |
T |
12: 4,944,563 (GRCm39) |
L53* |
probably null |
Het |
| Ulk2 |
A |
G |
11: 61,721,438 (GRCm39) |
L208P |
probably damaging |
Het |
| Unc80 |
G |
A |
1: 66,564,929 (GRCm39) |
C872Y |
possibly damaging |
Het |
| Vac14 |
A |
G |
8: 111,438,319 (GRCm39) |
H644R |
probably damaging |
Het |
| Vmn1r20 |
C |
A |
6: 57,409,306 (GRCm39) |
H211N |
probably benign |
Het |
| Vmn1r31 |
C |
T |
6: 58,449,029 (GRCm39) |
V279I |
probably damaging |
Het |
| Vmn2r18 |
G |
T |
5: 151,499,190 (GRCm39) |
Q425K |
probably benign |
Het |
| Vmn2r60 |
T |
C |
7: 41,786,094 (GRCm39) |
V299A |
probably damaging |
Het |
| Vps54 |
A |
T |
11: 21,262,967 (GRCm39) |
T685S |
possibly damaging |
Het |
| Vwa5b1 |
A |
G |
4: 138,302,700 (GRCm39) |
W932R |
probably damaging |
Het |
| Wdr53 |
A |
T |
16: 32,075,316 (GRCm39) |
I174F |
possibly damaging |
Het |
| Zfp157 |
A |
G |
5: 138,443,102 (GRCm39) |
D31G |
probably damaging |
Het |
| Zfp60 |
T |
C |
7: 27,449,435 (GRCm39) |
L701P |
probably benign |
Het |
| Zfp609 |
A |
T |
9: 65,702,040 (GRCm39) |
M204K |
probably benign |
Het |
| Zfp831 |
A |
G |
2: 174,545,870 (GRCm39) |
H1325R |
possibly damaging |
Het |
| Zfp995 |
A |
T |
17: 22,099,622 (GRCm39) |
I204N |
probably benign |
Het |
| Zp2 |
C |
T |
7: 119,732,624 (GRCm39) |
D641N |
probably benign |
Het |
|
| Other mutations in Cntn4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Cntn4
|
APN |
6 |
106,483,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00725:Cntn4
|
APN |
6 |
106,639,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Cntn4
|
APN |
6 |
106,595,239 (GRCm39) |
splice site |
probably benign |
|
|
IGL01432:Cntn4
|
APN |
6 |
106,655,295 (GRCm39) |
splice site |
probably benign |
|
|
IGL01585:Cntn4
|
APN |
6 |
106,595,289 (GRCm39) |
nonsense |
probably null |
|
|
IGL01710:Cntn4
|
APN |
6 |
106,527,392 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL01870:Cntn4
|
APN |
6 |
106,466,676 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01933:Cntn4
|
APN |
6 |
106,671,345 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01937:Cntn4
|
APN |
6 |
106,414,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01945:Cntn4
|
APN |
6 |
106,414,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02007:Cntn4
|
APN |
6 |
106,632,490 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02506:Cntn4
|
APN |
6 |
106,595,349 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL02561:Cntn4
|
APN |
6 |
106,500,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03080:Cntn4
|
APN |
6 |
106,632,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03338:Cntn4
|
APN |
6 |
106,632,550 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03097:Cntn4
|
UTSW |
6 |
106,330,673 (GRCm39) |
missense |
probably benign |
0.10 |
|
LCD18:Cntn4
|
UTSW |
6 |
106,530,901 (GRCm39) |
intron |
probably benign |
|
|
R0083:Cntn4
|
UTSW |
6 |
106,502,330 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0098:Cntn4
|
UTSW |
6 |
106,595,385 (GRCm39) |
splice site |
probably benign |
|
|
R0501:Cntn4
|
UTSW |
6 |
106,595,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0626:Cntn4
|
UTSW |
6 |
106,639,539 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0633:Cntn4
|
UTSW |
6 |
106,656,209 (GRCm39) |
splice site |
probably null |
|
|
R0730:Cntn4
|
UTSW |
6 |
106,527,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0849:Cntn4
|
UTSW |
6 |
106,644,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0883:Cntn4
|
UTSW |
6 |
106,644,501 (GRCm39) |
splice site |
probably benign |
|
|
R0926:Cntn4
|
UTSW |
6 |
106,632,542 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1199:Cntn4
|
UTSW |
6 |
106,330,558 (GRCm39) |
splice site |
probably benign |
|
|
R1293:Cntn4
|
UTSW |
6 |
106,330,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1296:Cntn4
|
UTSW |
6 |
106,486,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1344:Cntn4
|
UTSW |
6 |
106,321,831 (GRCm39) |
splice site |
probably null |
|
|
R1418:Cntn4
|
UTSW |
6 |
106,321,831 (GRCm39) |
splice site |
probably null |
|
|
R1660:Cntn4
|
UTSW |
6 |
106,656,258 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1751:Cntn4
|
UTSW |
6 |
106,595,371 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1884:Cntn4
|
UTSW |
6 |
106,656,353 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1899:Cntn4
|
UTSW |
6 |
106,652,774 (GRCm39) |
missense |
probably benign |
0.21 |
|
R1906:Cntn4
|
UTSW |
6 |
106,330,607 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2048:Cntn4
|
UTSW |
6 |
106,414,825 (GRCm39) |
splice site |
probably benign |
|
|
R2113:Cntn4
|
UTSW |
6 |
106,466,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Cntn4
|
UTSW |
6 |
106,414,925 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3277:Cntn4
|
UTSW |
6 |
106,414,925 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3944:Cntn4
|
UTSW |
6 |
106,595,375 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4401:Cntn4
|
UTSW |
6 |
106,466,625 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4540:Cntn4
|
UTSW |
6 |
106,652,709 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4688:Cntn4
|
UTSW |
6 |
106,414,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Cntn4
|
UTSW |
6 |
106,502,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4810:Cntn4
|
UTSW |
6 |
106,632,572 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4816:Cntn4
|
UTSW |
6 |
106,527,458 (GRCm39) |
missense |
probably benign |
|
|
R4873:Cntn4
|
UTSW |
6 |
106,414,874 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4875:Cntn4
|
UTSW |
6 |
106,414,874 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R4953:Cntn4
|
UTSW |
6 |
106,502,379 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5288:Cntn4
|
UTSW |
6 |
106,158,765 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5336:Cntn4
|
UTSW |
6 |
106,639,595 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5386:Cntn4
|
UTSW |
6 |
106,158,765 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5477:Cntn4
|
UTSW |
6 |
106,650,911 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5514:Cntn4
|
UTSW |
6 |
106,649,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Cntn4
|
UTSW |
6 |
106,656,397 (GRCm39) |
splice site |
silent |
|
|
R6334:Cntn4
|
UTSW |
6 |
106,321,747 (GRCm39) |
missense |
probably benign |
|
|
R6334:Cntn4
|
UTSW |
6 |
106,483,153 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6904:Cntn4
|
UTSW |
6 |
106,674,544 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6985:Cntn4
|
UTSW |
6 |
106,656,378 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7246:Cntn4
|
UTSW |
6 |
106,483,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7282:Cntn4
|
UTSW |
6 |
106,502,421 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7585:Cntn4
|
UTSW |
6 |
106,466,572 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Cntn4
|
UTSW |
6 |
106,656,856 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7781:Cntn4
|
UTSW |
6 |
106,500,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7882:Cntn4
|
UTSW |
6 |
106,330,684 (GRCm39) |
missense |
probably benign |
|
|
R8081:Cntn4
|
UTSW |
6 |
106,651,568 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8105:Cntn4
|
UTSW |
6 |
106,330,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8221:Cntn4
|
UTSW |
6 |
106,486,471 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8910:Cntn4
|
UTSW |
6 |
106,632,497 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8911:Cntn4
|
UTSW |
6 |
106,330,743 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8916:Cntn4
|
UTSW |
6 |
106,652,915 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9249:Cntn4
|
UTSW |
6 |
106,466,722 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9376:Cntn4
|
UTSW |
6 |
106,639,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9616:Cntn4
|
UTSW |
6 |
106,674,525 (GRCm39) |
nonsense |
probably null |
|
|
R9767:Cntn4
|
UTSW |
6 |
106,655,395 (GRCm39) |
missense |
probably benign |
0.40 |
|
Z1176:Cntn4
|
UTSW |
6 |
106,500,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Cntn4
|
UTSW |
6 |
106,486,425 (GRCm39) |
missense |
probably benign |
0.28 |
|
Z1177:Cntn4
|
UTSW |
6 |
106,639,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cntn4
|
UTSW |
6 |
106,527,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCTCCCCAGTGGATATAATTTCC -3'
(R):5'- TGGCATGCTATTCTGAAAGGTTC -3'
Sequencing Primer
(F):5'- CCCCAGTGGATATAATTTCCAAGGTC -3'
(R):5'- GGTTCAGTTAAAATGCTAAGGTGC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation