Incidental Mutation 'R1883:Rasgrf2'
| ID |
209302 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rasgrf2
|
| Ensembl Gene |
ENSMUSG00000021708 |
| Gene Name |
RAS protein-specific guanine nucleotide-releasing factor 2 |
| Synonyms |
Grf2, 6330417G04Rik |
| MMRRC Submission |
039904-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.191)
|
| Stock # |
R1883 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
92028519-92268164 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 92117149 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 820
(V820A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096930
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099326]
|
| AlphaFold |
P70392 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099326
AA Change: V820A
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000096930
Gene: ENSMUSG00000021708
AA Change: V820A
| Domain | Start | End | E-Value | Type |
|---|
|
PH
|
23 |
135 |
1.29e-16 |
SMART |
|
IQ
|
204 |
226 |
1.3e0 |
SMART |
|
RhoGEF
|
247 |
428 |
2.2e-51 |
SMART |
|
RasGEFN
|
633 |
775 |
9.35e-15 |
SMART |
|
RasGEFN
|
786 |
923 |
6.04e-9 |
SMART |
|
RasGEF
|
949 |
1186 |
2.97e-112 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000142378
AA Change: V220A
|
| SMART Domains |
Protein: ENSMUSP00000115401
Gene: ENSMUSG00000021708
AA Change: V220A
| Domain | Start | End | E-Value | Type |
|---|
|
RasGEFN
|
33 |
175 |
9.35e-15 |
SMART |
|
Blast:RasGEFN
|
187 |
249 |
8e-29 |
BLAST |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000151408
AA Change: V219A
|
| SMART Domains |
Protein: ENSMUSP00000116892
Gene: ENSMUSG00000021708
AA Change: V219A
| Domain | Start | End | E-Value | Type |
|---|
|
RasGEFN
|
33 |
175 |
9.35e-15 |
SMART |
|
RasGEFN
|
186 |
323 |
6.04e-9 |
SMART |
|
RasGEF
|
349 |
586 |
2.97e-112 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit decreased Il2 and TNF-alpha production in stimulated T cells. Mice homozygous for mutations in both Rasgrf1 and Rasgrf2 exhibit no additional abnormalities than those observed in the Rasgrf1 mutant mice. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ano9 |
T |
C |
7: 140,682,244 (GRCm39) |
E677G |
probably benign |
Het |
| Auh |
G |
A |
13: 52,989,532 (GRCm39) |
P308L |
probably benign |
Het |
| Bhmt1b |
T |
C |
18: 87,774,669 (GRCm39) |
L64P |
probably damaging |
Het |
| Brs3 |
T |
C |
X: 56,092,449 (GRCm39) |
I311T |
probably benign |
Het |
| Capn9 |
A |
G |
8: 125,338,297 (GRCm39) |
K552R |
probably benign |
Het |
| Catsperg1 |
C |
T |
7: 28,881,661 (GRCm39) |
|
probably null |
Het |
| Cdc16 |
A |
G |
8: 13,825,738 (GRCm39) |
N449D |
probably damaging |
Het |
| Cdyl2 |
A |
T |
8: 117,321,902 (GRCm39) |
N208K |
probably damaging |
Het |
| Cnot4 |
C |
T |
6: 35,055,092 (GRCm39) |
V66I |
probably damaging |
Het |
| Cntn4 |
A |
G |
6: 106,656,353 (GRCm39) |
T885A |
probably benign |
Het |
| Col20a1 |
C |
T |
2: 180,634,703 (GRCm39) |
T131I |
possibly damaging |
Het |
| Crybg2 |
C |
A |
4: 133,801,594 (GRCm39) |
S918* |
probably null |
Het |
| Dact2 |
A |
T |
17: 14,418,085 (GRCm39) |
S207T |
possibly damaging |
Het |
| Dbnl |
G |
A |
11: 5,749,247 (GRCm39) |
G356E |
probably benign |
Het |
| Ddx18 |
C |
A |
1: 121,495,645 (GRCm39) |
|
probably benign |
Het |
| Dis3 |
A |
T |
14: 99,328,905 (GRCm39) |
H282Q |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,677,142 (GRCm39) |
D453G |
probably benign |
Het |
| Dst |
T |
C |
1: 34,228,389 (GRCm39) |
V1994A |
possibly damaging |
Het |
| Dusp8 |
C |
T |
7: 141,638,085 (GRCm39) |
|
probably null |
Het |
| Eipr1 |
A |
T |
12: 28,816,850 (GRCm39) |
H69L |
possibly damaging |
Het |
| Eml1 |
A |
G |
12: 108,429,911 (GRCm39) |
R65G |
probably damaging |
Het |
| Epha7 |
C |
T |
4: 28,950,362 (GRCm39) |
H722Y |
possibly damaging |
Het |
| Epyc |
A |
T |
10: 97,511,695 (GRCm39) |
K229N |
possibly damaging |
Het |
| Extl1 |
A |
G |
4: 134,091,917 (GRCm39) |
I312T |
probably benign |
Het |
| F13a1 |
G |
C |
13: 37,172,981 (GRCm39) |
A133G |
probably benign |
Het |
| Fam185a |
G |
T |
5: 21,630,242 (GRCm39) |
C26F |
possibly damaging |
Het |
| Fam186b |
T |
C |
15: 99,176,679 (GRCm39) |
N737S |
probably damaging |
Het |
| Fam78b |
A |
G |
1: 166,829,171 (GRCm39) |
I13V |
probably benign |
Het |
| Fat1 |
A |
T |
8: 45,504,184 (GRCm39) |
Q4559L |
probably benign |
Het |
| Fnip1 |
T |
C |
11: 54,406,373 (GRCm39) |
S1157P |
probably damaging |
Het |
| Foxj3 |
A |
C |
4: 119,467,226 (GRCm39) |
M190L |
probably benign |
Het |
| Heatr3 |
T |
C |
8: 88,871,221 (GRCm39) |
Y192H |
possibly damaging |
Het |
| Hexd |
T |
A |
11: 121,098,524 (GRCm39) |
S3T |
probably benign |
Het |
| Klf3 |
C |
T |
5: 64,980,224 (GRCm39) |
P5S |
probably damaging |
Het |
| Klf9 |
C |
T |
19: 23,142,101 (GRCm39) |
S187L |
probably damaging |
Het |
| Krt9 |
T |
C |
11: 100,079,523 (GRCm39) |
H623R |
unknown |
Het |
| Krtap2-4 |
G |
C |
11: 99,505,505 (GRCm39) |
|
probably benign |
Het |
| Lmtk3 |
T |
C |
7: 45,436,273 (GRCm39) |
Y84H |
probably damaging |
Het |
| Mroh3 |
G |
T |
1: 136,134,731 (GRCm39) |
A166D |
probably damaging |
Het |
| Musk |
C |
A |
4: 58,373,189 (GRCm39) |
P697T |
probably benign |
Het |
| Nek9 |
A |
G |
12: 85,379,330 (GRCm39) |
L192P |
probably damaging |
Het |
| Nipbl |
A |
C |
15: 8,356,616 (GRCm39) |
F1590C |
probably damaging |
Het |
| Nrk |
G |
T |
X: 137,907,922 (GRCm39) |
V1455F |
probably damaging |
Het |
| Nsun3 |
T |
C |
16: 62,555,656 (GRCm39) |
D290G |
probably damaging |
Het |
| Obscn |
T |
C |
11: 58,969,029 (GRCm39) |
T222A |
probably damaging |
Het |
| Or2a12 |
T |
C |
6: 42,904,764 (GRCm39) |
S200P |
probably damaging |
Het |
| Or51f1d |
T |
C |
7: 102,701,189 (GRCm39) |
I228T |
probably benign |
Het |
| Or6b9 |
T |
C |
7: 106,555,981 (GRCm39) |
H54R |
probably benign |
Het |
| Osbpl11 |
T |
G |
16: 33,034,723 (GRCm39) |
H237Q |
probably benign |
Het |
| Pde10a |
A |
T |
17: 9,197,776 (GRCm39) |
T671S |
possibly damaging |
Het |
| Pkd2 |
A |
T |
5: 104,631,094 (GRCm39) |
N506I |
probably damaging |
Het |
| Ppp3cb |
A |
G |
14: 20,573,913 (GRCm39) |
V274A |
possibly damaging |
Het |
| Prex1 |
T |
C |
2: 166,425,192 (GRCm39) |
D938G |
probably benign |
Het |
| Ptch1 |
G |
A |
13: 63,659,841 (GRCm39) |
Q1134* |
probably null |
Het |
| Rimbp2 |
C |
T |
5: 128,880,998 (GRCm39) |
V137M |
possibly damaging |
Het |
| Rpa1 |
A |
G |
11: 75,209,309 (GRCm39) |
V137A |
probably benign |
Het |
| Rps6ka1 |
A |
C |
4: 133,591,354 (GRCm39) |
I299S |
probably damaging |
Het |
| Scn3b |
A |
C |
9: 40,190,669 (GRCm39) |
|
probably null |
Het |
| Sdha |
A |
T |
13: 74,481,255 (GRCm39) |
I317N |
probably damaging |
Het |
| Serpina1d |
T |
A |
12: 103,732,037 (GRCm39) |
D274V |
possibly damaging |
Het |
| Sik3 |
C |
G |
9: 46,132,387 (GRCm39) |
H1276Q |
probably benign |
Het |
| Snx14 |
T |
A |
9: 88,284,314 (GRCm39) |
E451D |
probably benign |
Het |
| Spmip4 |
T |
C |
6: 50,551,433 (GRCm39) |
T339A |
probably benign |
Het |
| Swt1 |
T |
A |
1: 151,299,284 (GRCm39) |
K8* |
probably null |
Het |
| Tas1r3 |
G |
T |
4: 155,946,610 (GRCm39) |
P332T |
probably damaging |
Het |
| Tas2r126 |
A |
T |
6: 42,411,961 (GRCm39) |
T165S |
probably benign |
Het |
| Tecpr1 |
A |
G |
5: 144,143,347 (GRCm39) |
V676A |
probably benign |
Het |
| Tg |
A |
G |
15: 66,543,158 (GRCm39) |
E24G |
probably damaging |
Het |
| Tlr7 |
C |
T |
X: 166,089,468 (GRCm39) |
G673S |
probably benign |
Het |
| Tnxb |
T |
A |
17: 34,908,539 (GRCm39) |
D1520E |
probably benign |
Het |
| Trabd |
A |
G |
15: 88,966,184 (GRCm39) |
E47G |
probably damaging |
Het |
| Trim29 |
T |
A |
9: 43,222,702 (GRCm39) |
I177N |
probably damaging |
Het |
| Ubxn2a |
A |
T |
12: 4,944,563 (GRCm39) |
L53* |
probably null |
Het |
| Ulk2 |
A |
G |
11: 61,721,438 (GRCm39) |
L208P |
probably damaging |
Het |
| Unc80 |
G |
A |
1: 66,564,929 (GRCm39) |
C872Y |
possibly damaging |
Het |
| Vac14 |
A |
G |
8: 111,438,319 (GRCm39) |
H644R |
probably damaging |
Het |
| Vmn1r20 |
C |
A |
6: 57,409,306 (GRCm39) |
H211N |
probably benign |
Het |
| Vmn1r31 |
C |
T |
6: 58,449,029 (GRCm39) |
V279I |
probably damaging |
Het |
| Vmn2r18 |
G |
T |
5: 151,499,190 (GRCm39) |
Q425K |
probably benign |
Het |
| Vmn2r60 |
T |
C |
7: 41,786,094 (GRCm39) |
V299A |
probably damaging |
Het |
| Vps54 |
A |
T |
11: 21,262,967 (GRCm39) |
T685S |
possibly damaging |
Het |
| Vwa5b1 |
A |
G |
4: 138,302,700 (GRCm39) |
W932R |
probably damaging |
Het |
| Wdr53 |
A |
T |
16: 32,075,316 (GRCm39) |
I174F |
possibly damaging |
Het |
| Zfp157 |
A |
G |
5: 138,443,102 (GRCm39) |
D31G |
probably damaging |
Het |
| Zfp60 |
T |
C |
7: 27,449,435 (GRCm39) |
L701P |
probably benign |
Het |
| Zfp609 |
A |
T |
9: 65,702,040 (GRCm39) |
M204K |
probably benign |
Het |
| Zfp831 |
A |
G |
2: 174,545,870 (GRCm39) |
H1325R |
possibly damaging |
Het |
| Zfp995 |
A |
T |
17: 22,099,622 (GRCm39) |
I204N |
probably benign |
Het |
| Zp2 |
C |
T |
7: 119,732,624 (GRCm39) |
D641N |
probably benign |
Het |
|
| Other mutations in Rasgrf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01308:Rasgrf2
|
APN |
13 |
92,159,425 (GRCm39) |
splice site |
probably benign |
|
|
IGL01358:Rasgrf2
|
APN |
13 |
92,130,749 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL01666:Rasgrf2
|
APN |
13 |
92,174,718 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01930:Rasgrf2
|
APN |
13 |
92,130,857 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02230:Rasgrf2
|
APN |
13 |
92,136,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02630:Rasgrf2
|
APN |
13 |
92,267,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02690:Rasgrf2
|
APN |
13 |
92,167,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02943:Rasgrf2
|
APN |
13 |
92,131,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Rasgrf2
|
APN |
13 |
92,159,413 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03342:Rasgrf2
|
APN |
13 |
92,136,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03405:Rasgrf2
|
APN |
13 |
92,044,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0620:Rasgrf2
|
UTSW |
13 |
92,067,936 (GRCm39) |
splice site |
probably benign |
|
|
R0632:Rasgrf2
|
UTSW |
13 |
92,120,393 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0894:Rasgrf2
|
UTSW |
13 |
92,130,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1354:Rasgrf2
|
UTSW |
13 |
92,165,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1400:Rasgrf2
|
UTSW |
13 |
92,035,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1437:Rasgrf2
|
UTSW |
13 |
92,167,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1443:Rasgrf2
|
UTSW |
13 |
92,131,795 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1522:Rasgrf2
|
UTSW |
13 |
92,044,205 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1553:Rasgrf2
|
UTSW |
13 |
92,038,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1613:Rasgrf2
|
UTSW |
13 |
92,050,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1934:Rasgrf2
|
UTSW |
13 |
92,131,825 (GRCm39) |
splice site |
probably null |
|
|
R1990:Rasgrf2
|
UTSW |
13 |
92,172,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2037:Rasgrf2
|
UTSW |
13 |
92,050,748 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2043:Rasgrf2
|
UTSW |
13 |
92,167,351 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2135:Rasgrf2
|
UTSW |
13 |
92,120,374 (GRCm39) |
missense |
probably benign |
|
|
R2193:Rasgrf2
|
UTSW |
13 |
92,160,221 (GRCm39) |
splice site |
probably null |
|
|
R2406:Rasgrf2
|
UTSW |
13 |
92,120,359 (GRCm39) |
missense |
probably benign |
|
|
R3055:Rasgrf2
|
UTSW |
13 |
92,165,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3916:Rasgrf2
|
UTSW |
13 |
92,167,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3954:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3955:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3956:Rasgrf2
|
UTSW |
13 |
92,130,974 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4133:Rasgrf2
|
UTSW |
13 |
92,130,773 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R4177:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4178:Rasgrf2
|
UTSW |
13 |
92,038,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4357:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4358:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4359:Rasgrf2
|
UTSW |
13 |
92,038,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4440:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4441:Rasgrf2
|
UTSW |
13 |
92,131,797 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4564:Rasgrf2
|
UTSW |
13 |
92,033,773 (GRCm39) |
nonsense |
probably null |
|
|
R4576:Rasgrf2
|
UTSW |
13 |
92,044,529 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R4590:Rasgrf2
|
UTSW |
13 |
92,174,789 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4718:Rasgrf2
|
UTSW |
13 |
92,138,716 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4778:Rasgrf2
|
UTSW |
13 |
92,131,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4790:Rasgrf2
|
UTSW |
13 |
92,136,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4808:Rasgrf2
|
UTSW |
13 |
92,160,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Rasgrf2
|
UTSW |
13 |
92,044,155 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5286:Rasgrf2
|
UTSW |
13 |
92,267,941 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5902:Rasgrf2
|
UTSW |
13 |
92,068,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6180:Rasgrf2
|
UTSW |
13 |
92,165,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6264:Rasgrf2
|
UTSW |
13 |
92,167,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6369:Rasgrf2
|
UTSW |
13 |
92,267,954 (GRCm39) |
missense |
probably benign |
|
|
R6428:Rasgrf2
|
UTSW |
13 |
92,136,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6595:Rasgrf2
|
UTSW |
13 |
92,167,361 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6619:Rasgrf2
|
UTSW |
13 |
92,165,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6988:Rasgrf2
|
UTSW |
13 |
92,033,754 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7026:Rasgrf2
|
UTSW |
13 |
92,131,732 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Rasgrf2
|
UTSW |
13 |
92,130,952 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7045:Rasgrf2
|
UTSW |
13 |
92,159,100 (GRCm39) |
intron |
probably benign |
|
|
R7056:Rasgrf2
|
UTSW |
13 |
92,167,203 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7058:Rasgrf2
|
UTSW |
13 |
92,034,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7256:Rasgrf2
|
UTSW |
13 |
92,032,637 (GRCm39) |
nonsense |
probably null |
|
|
R7392:Rasgrf2
|
UTSW |
13 |
92,041,856 (GRCm39) |
missense |
|
|
|
R7469:Rasgrf2
|
UTSW |
13 |
92,165,530 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7618:Rasgrf2
|
UTSW |
13 |
92,136,085 (GRCm39) |
missense |
|
|
|
R7641:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7674:Rasgrf2
|
UTSW |
13 |
92,267,914 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7784:Rasgrf2
|
UTSW |
13 |
92,044,201 (GRCm39) |
missense |
|
|
|
R7962:Rasgrf2
|
UTSW |
13 |
92,167,300 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8056:Rasgrf2
|
UTSW |
13 |
92,167,321 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8218:Rasgrf2
|
UTSW |
13 |
92,130,796 (GRCm39) |
missense |
|
|
|
R8796:Rasgrf2
|
UTSW |
13 |
92,038,685 (GRCm39) |
missense |
|
|
|
R8913:Rasgrf2
|
UTSW |
13 |
92,159,034 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8971:Rasgrf2
|
UTSW |
13 |
92,158,225 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9020:Rasgrf2
|
UTSW |
13 |
92,165,146 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9487:Rasgrf2
|
UTSW |
13 |
92,267,759 (GRCm39) |
missense |
probably benign |
|
|
R9562:Rasgrf2
|
UTSW |
13 |
92,034,469 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9712:Rasgrf2
|
UTSW |
13 |
92,136,092 (GRCm39) |
missense |
|
|
|
R9766:Rasgrf2
|
UTSW |
13 |
92,160,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9800:Rasgrf2
|
UTSW |
13 |
92,267,860 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0013:Rasgrf2
|
UTSW |
13 |
92,167,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Rasgrf2
|
UTSW |
13 |
92,050,654 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,159,081 (GRCm39) |
missense |
unknown |
|
|
Z1177:Rasgrf2
|
UTSW |
13 |
92,131,632 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGATGCAGCTGGTGTCTCCTTA -3'
(R):5'- AAACCTATTTATCAGTGGAGGGACA -3'
Sequencing Primer
(F):5'- AGTGACATCATGCAGCGTTTAG -3'
(R):5'- GAGGGACATCTAATTTTTGGCTACAG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation