Mutagenetix > Incidental Mutation

Incidental Mutation 'R1908:Rp1'

210013

Institutional Source

Beutler Lab

Gene Symbol

Rp1

Ensembl Gene

ENSMUSG00000025900

Gene Name

retinitis pigmentosa 1 (human)

Synonyms

Dcdc3, mG145, Orp1, oxygen-regulated protein 1, Rp1h

MMRRC Submission

039927-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.106) question?

Stock #

R1908 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

3999557-4409241 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 4348720 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 723 (I723T)

Ref Sequence

ENSEMBL: ENSMUSP00000027032 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000027032] [ENSMUST00000194992] [ENSMUST00000208660]

AlphaFold

P56716

Predicted Effect

probably damaging
Transcript: ENSMUST00000027032
AA Change: I723T

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000027032
Gene: ENSMUSG00000025900
AA Change: I723T

Domain	Start	End	E-Value	Type
DCX	30	117	4.37e-39	SMART
low complexity region	120	133	N/A	INTRINSIC
DCX	152	236	7.17e-35	SMART
low complexity region	343	354	N/A	INTRINSIC
low complexity region	403	414	N/A	INTRINSIC
low complexity region	462	473	N/A	INTRINSIC
low complexity region	646	661	N/A	INTRINSIC
low complexity region	1113	1123	N/A	INTRINSIC
low complexity region	1396	1412	N/A	INTRINSIC
low complexity region	1434	1444	N/A	INTRINSIC
low complexity region	1648	1661	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000194992

SMART Domains

Protein: ENSMUSP00000142146
Gene: ENSMUSG00000025900

Domain	Start	End	E-Value	Type
DCX	40	127	4.37e-39	SMART
low complexity region	130	143	N/A	INTRINSIC
DCX	162	246	7.17e-35	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000208660

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000208793

Coding Region Coverage

1x: 97.3%
3x: 96.8%
10x: 95.4%
20x: 93.0%

Validation Efficiency

MGI Phenotype

FUNCTION: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Two transcript variants encoding distinct isoforms are resulted from alternative promoters and alternative splicing. [provided by RefSeq, Sep 2010]
PHENOTYPE: Mice homozygous for disruptions in this gene experience progressive degeneration in photoreceptors but are otherwise phenotypically normal. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8b	C	A	11: 109,957,098 (GRCm38)	L852F	possibly damaging	Het
Abcc6	T	C	7: 46,020,134 (GRCm38)		probably null	Het
Alg11	T	G	8: 22,065,568 (GRCm38)	C240G	probably damaging	Het
Aox1	A	G	1: 58,102,624 (GRCm38)	I1190V	probably damaging	Het
Apc2	T	G	10: 80,314,844 (GRCm38)	S1911A	probably benign	Het
Arfgef3	T	C	10: 18,652,763 (GRCm38)	D292G	possibly damaging	Het
Arhgef4	C	A	1: 34,724,259 (GRCm38)	S865R	probably benign	Het
Ass1	T	A	2: 31,493,148 (GRCm38)	Y190*	probably null	Het
B4galnt3	A	T	6: 120,210,090 (GRCm38)		probably null	Het
Btnl10	C	A	11: 58,920,541 (GRCm38)	P230Q	possibly damaging	Het
C3	A	G	17: 57,209,489 (GRCm38)	Y1348H	probably damaging	Het
Ccdc198	G	T	14: 49,226,575 (GRCm38)	D292E	probably damaging	Het
Cebpz	A	T	17: 78,934,907 (GRCm38)	Y439*	probably null	Het
Cic	C	A	7: 25,286,840 (GRCm38)	T1229K	probably damaging	Het
Clip4	T	C	17: 71,837,749 (GRCm38)	S524P	probably damaging	Het
Col6a3	A	C	1: 90,811,699 (GRCm38)	I269R	probably damaging	Het
Dbh	C	T	2: 27,181,494 (GRCm38)	T533I	possibly damaging	Het
Dcaf17	A	T	2: 71,060,369 (GRCm38)	R83*	probably null	Het
Dnah1	A	G	14: 31,262,558 (GRCm38)	L3923P	probably damaging	Het
Dnah7a	A	T	1: 53,631,562 (GRCm38)	D510E	probably benign	Het
Dock6	A	G	9: 21,841,629 (GRCm38)	F296S	probably damaging	Het
Eif4enif1	T	C	11: 3,227,455 (GRCm38)	S341P	probably damaging	Het
Epb41l1	G	T	2: 156,510,817 (GRCm38)	G461V	possibly damaging	Het
Epg5	T	A	18: 77,959,032 (GRCm38)	D555E	probably benign	Het
Fes	T	C	7: 80,386,861 (GRCm38)	R113G	probably damaging	Het
Garre1	T	A	7: 34,258,036 (GRCm38)	I59L	probably benign	Het
Gm10684	A	G	9: 45,110,213 (GRCm38)		probably benign	Het
Gm12185	T	C	11: 48,915,404 (GRCm38)	E320G	probably benign	Het
Gm14412	A	C	2: 177,315,837 (GRCm38)	S88R	probably benign	Het
Gm14412	G	T	2: 177,315,476 (GRCm38)	H209N	probably damaging	Het
Grhl1	T	A	12: 24,608,556 (GRCm38)	L400Q	probably damaging	Het
Havcr1	T	A	11: 46,773,684 (GRCm38)	Y216*	probably null	Het
Hephl1	A	C	9: 15,074,124 (GRCm38)	Y745*	probably null	Het
Hmcn2	T	G	2: 31,411,910 (GRCm38)		probably null	Het
Hs3st6	A	G	17: 24,758,136 (GRCm38)	K197E	possibly damaging	Het
Ifi214	C	T	1: 173,529,511 (GRCm38)	V9I	probably benign	Het
Jakmip2	T	C	18: 43,567,144 (GRCm38)	T450A	probably benign	Het
Lrp4	T	A	2: 91,498,408 (GRCm38)	V1551D	possibly damaging	Het
Macf1	A	T	4: 123,457,841 (GRCm38)	H1634Q	possibly damaging	Het
Mcpt8	T	A	14: 56,083,834 (GRCm38)	I58F	probably benign	Het
Mga	T	A	2: 119,926,594 (GRCm38)	H1018Q	possibly damaging	Het
Myo10	T	A	15: 25,801,222 (GRCm38)	V1499E	probably damaging	Het
Myom2	G	T	8: 15,081,023 (GRCm38)	D320Y	probably damaging	Het
Or11g7	T	A	14: 50,453,838 (GRCm38)	M262K	probably damaging	Het
Or13a27	T	C	7: 140,345,465 (GRCm38)	I175V	probably benign	Het
Or2r11	C	T	6: 42,460,426 (GRCm38)	V198M	probably benign	Het
Or2t26	A	C	11: 49,148,274 (GRCm38)	N6H	possibly damaging	Het
Or4c115	G	A	2: 89,097,544 (GRCm38)	P128S	probably damaging	Het
Or5d47	A	T	2: 87,974,059 (GRCm38)	V202D	possibly damaging	Het
Pabpc4	G	T	4: 123,289,068 (GRCm38)	R166L	possibly damaging	Het
Pcdhb8	A	G	18: 37,355,962 (GRCm38)	E231G	possibly damaging	Het
Pomgnt2	A	T	9: 121,982,191 (GRCm38)	I508N	possibly damaging	Het
Ppp2r5e	C	G	12: 75,469,567 (GRCm38)	A239P	probably damaging	Het
Prdm15	G	T	16: 97,837,685 (GRCm38)	D58E	probably benign	Het
Rgl2	A	G	17: 33,932,148 (GRCm38)	T117A	probably benign	Het
Serpina3g	A	G	12: 104,241,277 (GRCm38)	E233G	probably damaging	Het
Skint6	T	A	4: 112,891,990 (GRCm38)	S798C	probably benign	Het
Slc35f1	T	C	10: 53,021,904 (GRCm38)	L137P	possibly damaging	Het
Slc6a20a	T	C	9: 123,656,308 (GRCm38)	N246S	probably damaging	Het
Slc7a2	T	C	8: 40,916,497 (GRCm38)	L663S	probably benign	Het
Slco1a4	A	G	6: 141,815,447 (GRCm38)		probably null	Het
Slit2	A	G	5: 48,281,988 (GRCm38)	T41A	probably damaging	Het
Smc2	T	C	4: 52,450,863 (GRCm38)	I227T	probably damaging	Het
Smg1	A	G	7: 118,154,199 (GRCm38)		probably benign	Het
Ssu2	A	T	6: 112,384,427 (GRCm38)	L23M	probably benign	Het
St5	G	A	7: 109,525,326 (GRCm38)	Q686*	probably null	Het
Syne2	A	G	12: 76,094,279 (GRCm38)		probably null	Het
Tekt1	T	C	11: 72,351,935 (GRCm38)	T249A	probably benign	Het
Tfr2	T	C	5: 137,571,692 (GRCm38)	V120A	probably benign	Het
Thsd7b	C	T	1: 129,678,109 (GRCm38)	P529L	probably damaging	Het
Tll1	C	T	8: 64,025,107 (GRCm38)	D871N	probably damaging	Het
Tlr11	A	C	14: 50,361,207 (GRCm38)	I217L	probably benign	Het
Tmem87b	T	A	2: 128,831,559 (GRCm38)	V241D	probably damaging	Het
Tshz2	T	A	2: 169,885,545 (GRCm38)	I218N	possibly damaging	Het
Vmn1r18	A	T	6: 57,390,041 (GRCm38)	I176N	possibly damaging	Het
Vmn2r68	T	A	7: 85,234,052 (GRCm38)	H164L	probably benign	Het
Vmn2r74	T	C	7: 85,952,442 (GRCm38)	T663A	probably benign	Het
Vmn2r8	T	C	5: 108,797,570 (GRCm38)	T724A	probably benign	Het
Wdr11	T	C	7: 129,605,230 (GRCm38)	V289A	possibly damaging	Het
Zfp62	T	A	11: 49,216,220 (GRCm38)	D379E	probably damaging	Het
Zfp78	C	T	7: 6,378,898 (GRCm38)	P316S	probably damaging	Het
Zfyve27	T	G	19: 42,171,548 (GRCm38)	M1R	probably null	Het
Zkscan8	G	A	13: 21,525,155 (GRCm38)	P191L	probably damaging	Het

Other mutations in Rp1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00323:Rp1	APN	1	4,346,746 (GRCm38)	missense	probably damaging	0.98
IGL00593:Rp1	APN	1	4,345,403 (GRCm38)	missense	possibly damaging	0.70
IGL00956:Rp1	APN	1	4,352,212 (GRCm38)	missense	probably damaging	1.00
IGL01070:Rp1	APN	1	4,345,238 (GRCm38)	missense	probably damaging	1.00
IGL01531:Rp1	APN	1	4,348,945 (GRCm38)	missense	probably benign	0.00
IGL01668:Rp1	APN	1	4,345,718 (GRCm38)	missense	probably damaging	1.00
IGL01907:Rp1	APN	1	4,348,507 (GRCm38)	missense	possibly damaging	0.56
IGL02055:Rp1	APN	1	4,352,522 (GRCm38)	missense	probably damaging	1.00
IGL02071:Rp1	APN	1	4,345,310 (GRCm38)	missense	possibly damaging	0.46
IGL02128:Rp1	APN	1	4,347,385 (GRCm38)	missense	probably damaging	0.99
IGL02244:Rp1	APN	1	4,348,780 (GRCm38)	missense	probably benign	0.00
IGL02381:Rp1	APN	1	4,352,390 (GRCm38)	missense	probably benign	0.01
IGL02499:Rp1	APN	1	4,349,048 (GRCm38)	missense	probably benign	0.17
IGL02619:Rp1	APN	1	4,348,450 (GRCm38)	missense	possibly damaging	0.73
IGL02832:Rp1	APN	1	4,349,713 (GRCm38)	missense	probably benign	0.03
IGL02861:Rp1	APN	1	4,346,152 (GRCm38)	nonsense	probably null
IGL03288:Rp1	APN	1	4,349,524 (GRCm38)	missense	possibly damaging	0.88
IGL03290:Rp1	APN	1	4,350,041 (GRCm38)	missense	probably damaging	1.00
IGL03303:Rp1	APN	1	4,344,817 (GRCm38)	missense	probably damaging	1.00
R0041:Rp1	UTSW	1	4,344,628 (GRCm38)	missense	probably benign	0.36
R0111:Rp1	UTSW	1	4,344,760 (GRCm38)	missense	probably damaging	1.00
R0363:Rp1	UTSW	1	4,347,718 (GRCm38)	missense	probably damaging	1.00
R0440:Rp1	UTSW	1	4,345,640 (GRCm38)	missense	probably damaging	1.00
R0442:Rp1	UTSW	1	4,346,747 (GRCm38)	missense	probably benign	0.09
R0528:Rp1	UTSW	1	4,344,865 (GRCm38)	missense	possibly damaging	0.82
R0586:Rp1	UTSW	1	4,347,837 (GRCm38)	missense	possibly damaging	0.76
R0639:Rp1	UTSW	1	4,346,498 (GRCm38)	missense	probably benign	0.00
R0856:Rp1	UTSW	1	4,344,655 (GRCm38)	missense	probably benign	0.05
R0908:Rp1	UTSW	1	4,344,655 (GRCm38)	missense	probably benign	0.05
R0968:Rp1	UTSW	1	4,345,352 (GRCm38)	missense	probably benign	0.00
R1099:Rp1	UTSW	1	4,352,290 (GRCm38)	missense	possibly damaging	0.45
R1242:Rp1	UTSW	1	4,344,962 (GRCm38)	missense	probably benign	0.03
R1301:Rp1	UTSW	1	4,345,936 (GRCm38)	missense	possibly damaging	0.56
R1327:Rp1	UTSW	1	4,347,970 (GRCm38)	missense	probably benign	0.01
R1403:Rp1	UTSW	1	4,346,297 (GRCm38)	missense	possibly damaging	0.73
R1403:Rp1	UTSW	1	4,346,297 (GRCm38)	missense	possibly damaging	0.73
R1406:Rp1	UTSW	1	4,351,921 (GRCm38)	missense	possibly damaging	0.88
R1406:Rp1	UTSW	1	4,351,921 (GRCm38)	missense	possibly damaging	0.88
R1440:Rp1	UTSW	1	4,347,396 (GRCm38)	missense	probably damaging	1.00
R1509:Rp1	UTSW	1	4,348,537 (GRCm38)	missense	probably benign	0.20
R1509:Rp1	UTSW	1	4,347,694 (GRCm38)	missense	probably damaging	0.98
R1538:Rp1	UTSW	1	4,345,676 (GRCm38)	missense	probably damaging	1.00
R1609:Rp1	UTSW	1	4,349,201 (GRCm38)	missense	probably damaging	1.00
R1666:Rp1	UTSW	1	4,349,863 (GRCm38)	missense	probably damaging	1.00
R1703:Rp1	UTSW	1	4,345,169 (GRCm38)	missense	probably damaging	1.00
R1782:Rp1	UTSW	1	4,349,089 (GRCm38)	missense	probably benign	0.00
R1799:Rp1	UTSW	1	4,348,832 (GRCm38)	missense	possibly damaging	0.94
R1848:Rp1	UTSW	1	4,347,232 (GRCm38)	missense	possibly damaging	0.76
R1919:Rp1	UTSW	1	4,352,671 (GRCm38)	missense	probably damaging	0.99
R2087:Rp1	UTSW	1	4,348,352 (GRCm38)	missense	probably damaging	1.00
R2211:Rp1	UTSW	1	4,348,139 (GRCm38)	missense	probably damaging	0.96
R2278:Rp1	UTSW	1	4,348,027 (GRCm38)	missense	possibly damaging	0.51
R2287:Rp1	UTSW	1	4,345,959 (GRCm38)	nonsense	probably null
R2316:Rp1	UTSW	1	4,345,640 (GRCm38)	missense	probably damaging	1.00
R2346:Rp1	UTSW	1	4,348,013 (GRCm38)	missense	probably damaging	1.00
R2878:Rp1	UTSW	1	4,348,139 (GRCm38)	missense	probably damaging	1.00
R3023:Rp1	UTSW	1	4,352,675 (GRCm38)	missense	probably damaging	1.00
R3025:Rp1	UTSW	1	4,352,675 (GRCm38)	missense	probably damaging	1.00
R3716:Rp1	UTSW	1	4,349,765 (GRCm38)	missense	probably benign	0.38
R3814:Rp1	UTSW	1	4,349,708 (GRCm38)	missense	probably benign
R3929:Rp1	UTSW	1	4,352,645 (GRCm38)	missense	probably damaging	1.00
R4064:Rp1	UTSW	1	4,345,400 (GRCm38)	missense	probably benign	0.08
R4426:Rp1	UTSW	1	4,347,924 (GRCm38)	missense	probably benign	0.13
R4557:Rp1	UTSW	1	4,344,663 (GRCm38)	missense	possibly damaging	0.61
R4764:Rp1	UTSW	1	4,345,878 (GRCm38)	missense	probably damaging	0.96
R4845:Rp1	UTSW	1	4,349,228 (GRCm38)	missense	probably benign	0.02
R4850:Rp1	UTSW	1	4,348,675 (GRCm38)	missense	probably damaging	1.00
R4857:Rp1	UTSW	1	4,352,317 (GRCm38)	missense	probably damaging	1.00
R4857:Rp1	UTSW	1	4,352,316 (GRCm38)	missense	probably damaging	0.99
R5159:Rp1	UTSW	1	4,346,203 (GRCm38)	missense	possibly damaging	0.73
R5226:Rp1	UTSW	1	4,348,033 (GRCm38)	missense	probably benign	0.01
R5327:Rp1	UTSW	1	4,349,360 (GRCm38)	splice site	probably null
R5352:Rp1	UTSW	1	4,347,098 (GRCm38)	missense	probably benign	0.00
R5504:Rp1	UTSW	1	4,349,890 (GRCm38)	missense	probably damaging	1.00
R5527:Rp1	UTSW	1	4,346,393 (GRCm38)	missense	possibly damaging	0.75
R5529:Rp1	UTSW	1	4,345,832 (GRCm38)	missense	probably benign	0.42
R5569:Rp1	UTSW	1	4,345,237 (GRCm38)	missense	probably damaging	1.00
R5622:Rp1	UTSW	1	4,347,837 (GRCm38)	missense	possibly damaging	0.76
R5970:Rp1	UTSW	1	4,348,462 (GRCm38)	missense	probably benign	0.05
R5992:Rp1	UTSW	1	4,148,703 (GRCm38)	missense	unknown
R6004:Rp1	UTSW	1	4,197,585 (GRCm38)	missense	unknown
R6018:Rp1	UTSW	1	4,352,836 (GRCm38)	missense	possibly damaging	0.83
R6074:Rp1	UTSW	1	4,345,379 (GRCm38)	missense	probably benign	0.02
R6127:Rp1	UTSW	1	4,349,311 (GRCm38)	missense	possibly damaging	0.80
R6187:Rp1	UTSW	1	4,349,869 (GRCm38)	missense	probably damaging	1.00
R6301:Rp1	UTSW	1	4,347,254 (GRCm38)	missense	probably benign	0.04
R6317:Rp1	UTSW	1	4,041,989 (GRCm38)	missense	unknown
R6405:Rp1	UTSW	1	4,345,771 (GRCm38)	missense	probably damaging	1.00
R6445:Rp1	UTSW	1	4,226,617 (GRCm38)	missense	unknown
R6466:Rp1	UTSW	1	4,347,886 (GRCm38)	missense	probably benign	0.01
R6501:Rp1	UTSW	1	4,311,280 (GRCm38)	intron	probably benign
R6547:Rp1	UTSW	1	4,170,305 (GRCm38)	missense	unknown
R6604:Rp1	UTSW	1	4,019,128 (GRCm38)	missense	unknown
R6700:Rp1	UTSW	1	4,349,896 (GRCm38)	missense	probably damaging	1.00
R6706:Rp1	UTSW	1	4,142,664 (GRCm38)	missense	unknown
R6831:Rp1	UTSW	1	4,349,864 (GRCm38)	splice site	probably null
R6918:Rp1	UTSW	1	3,999,608 (GRCm38)	missense	unknown
R6973:Rp1	UTSW	1	4,351,994 (GRCm38)	nonsense	probably null
R6981:Rp1	UTSW	1	4,345,655 (GRCm38)	missense	probably benign	0.06
R7009:Rp1	UTSW	1	4,042,068 (GRCm38)	missense	unknown
R7078:Rp1	UTSW	1	4,206,791 (GRCm38)	missense	unknown
R7112:Rp1	UTSW	1	4,349,018 (GRCm38)	missense	probably benign	0.43
R7135:Rp1	UTSW	1	4,348,168 (GRCm38)	missense	possibly damaging	0.83
R7165:Rp1	UTSW	1	4,349,917 (GRCm38)	missense	probably damaging	0.99
R7199:Rp1	UTSW	1	4,347,290 (GRCm38)	missense	possibly damaging	0.73
R7232:Rp1	UTSW	1	4,228,601 (GRCm38)	missense	unknown
R7367:Rp1	UTSW	1	4,347,998 (GRCm38)	missense	probably benign	0.42
R7484:Rp1	UTSW	1	4,345,481 (GRCm38)	missense	probably benign	0.10
R7500:Rp1	UTSW	1	4,311,278 (GRCm38)	missense	unknown
R7569:Rp1	UTSW	1	4,284,840 (GRCm38)	missense	unknown
R7642:Rp1	UTSW	1	4,147,831 (GRCm38)	missense	unknown
R7693:Rp1	UTSW	1	4,347,403 (GRCm38)	missense	probably damaging	1.00
R7742:Rp1	UTSW	1	4,170,234 (GRCm38)	missense	unknown
R7759:Rp1	UTSW	1	4,344,884 (GRCm38)	missense	probably benign
R7784:Rp1	UTSW	1	4,142,658 (GRCm38)	missense	unknown
R7816:Rp1	UTSW	1	4,347,703 (GRCm38)	missense	probably damaging	0.98
R7866:Rp1	UTSW	1	4,347,701 (GRCm38)	missense	probably benign	0.02
R8215:Rp1	UTSW	1	4,245,095 (GRCm38)	missense	unknown
R8281:Rp1	UTSW	1	4,347,916 (GRCm38)	missense	probably damaging	1.00
R8294:Rp1	UTSW	1	4,345,997 (GRCm38)	missense	probably benign	0.09
R8309:Rp1	UTSW	1	4,347,089 (GRCm38)	missense	probably benign	0.00
R8311:Rp1	UTSW	1	4,348,349 (GRCm38)	missense	probably benign	0.11
R8500:Rp1	UTSW	1	4,346,590 (GRCm38)	missense	possibly damaging	0.91
R8559:Rp1	UTSW	1	4,349,561 (GRCm38)	missense	probably damaging	1.00
R8672:Rp1	UTSW	1	4,348,784 (GRCm38)	missense	possibly damaging	0.55
R8688:Rp1	UTSW	1	4,346,405 (GRCm38)	missense	probably benign	0.01
R8792:Rp1	UTSW	1	4,024,868 (GRCm38)	missense	unknown
R8859:Rp1	UTSW	1	4,349,960 (GRCm38)	missense	probably benign	0.07
R8945:Rp1	UTSW	1	4,349,594 (GRCm38)	missense	probably benign	0.42
R8959:Rp1	UTSW	1	4,349,427 (GRCm38)	intron	probably benign
R8979:Rp1	UTSW	1	4,148,714 (GRCm38)	missense	unknown
R9126:Rp1	UTSW	1	4,346,913 (GRCm38)	missense	probably damaging	0.99
R9156:Rp1	UTSW	1	4,163,938 (GRCm38)	missense	unknown
R9160:Rp1	UTSW	1	4,346,497 (GRCm38)	missense	probably benign	0.00
R9221:Rp1	UTSW	1	4,245,043 (GRCm38)	missense	unknown
R9263:Rp1	UTSW	1	4,348,937 (GRCm38)	missense	probably benign	0.02
R9263:Rp1	UTSW	1	4,348,452 (GRCm38)	missense	probably benign	0.25
R9302:Rp1	UTSW	1	4,346,566 (GRCm38)	missense	probably damaging	1.00
R9318:Rp1	UTSW	1	4,348,265 (GRCm38)	missense	probably benign	0.09
R9414:Rp1	UTSW	1	4,243,618 (GRCm38)	missense	unknown
R9474:Rp1	UTSW	1	4,092,615 (GRCm38)	critical splice donor site	probably null
R9478:Rp1	UTSW	1	4,347,322 (GRCm38)	missense	probably benign	0.06
R9529:Rp1	UTSW	1	4,346,224 (GRCm38)	missense	probably benign
R9572:Rp1	UTSW	1	4,348,439 (GRCm38)	missense	probably benign
R9673:Rp1	UTSW	1	4,267,569 (GRCm38)	missense	unknown
R9709:Rp1	UTSW	1	4,042,032 (GRCm38)	missense	unknown
R9716:Rp1	UTSW	1	4,142,610 (GRCm38)	critical splice donor site	probably null
RF003:Rp1	UTSW	1	4,344,694 (GRCm38)	missense	probably damaging	0.99
V1662:Rp1	UTSW	1	4,349,560 (GRCm38)	missense	probably damaging	1.00
X0012:Rp1	UTSW	1	4,347,695 (GRCm38)	missense	probably damaging	0.96

Predicted Primers

PCR Primer
(F):5'- ACAGAGTTTCGAGTCACTATGGAG -3'
(R):5'- ATCTCAGCAGCGAATGATAACTTCC -3'

Sequencing Primer
(F):5'- CAATCTTTCGTGGCCTTG -3'
(R):5'- AGCGAATGATAACTTCCAATGATAAG -3'

Posted On

2014-06-30