Mutagenetix > Incidental Mutation

Incidental Mutation 'R1908:Smg1'

210057

Institutional Source

Beutler Lab

Gene Symbol

Smg1

Ensembl Gene

ENSMUSG00000030655

Gene Name

SMG1 nonsense mediated mRNA decay associated PI3K related kinase

Synonyms

5430435M13Rik, SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans), 2610207I05Rik, C130002K18Rik

MMRRC Submission

039927-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R1908 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

117730531-117842893 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

A to G at 117753422 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032891]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000032891
AA Change: V2675A

SMART Domains

Protein: ENSMUSP00000032891
Gene: ENSMUSG00000030655
AA Change: V2675A

Domain	Start	End	E-Value	Type
low complexity region	42	55	N/A	INTRINSIC
SCOP:d1gw5a_	147	621	7e-7	SMART
Pfam:SMG1	629	1240	9.8e-249	PFAM
low complexity region	1540	1551	N/A	INTRINSIC
SCOP:d1gw5a_	1680	1942	8e-3	SMART
low complexity region	2125	2141	N/A	INTRINSIC
PI3Kc	2149	2493	7.93e-50	SMART
low complexity region	2759	2770	N/A	INTRINSIC
low complexity region	3425	3442	N/A	INTRINSIC
FATC	3626	3658	8.66e-12	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000083940

Predicted Effect

probably benign
Transcript: ENSMUST00000179331

SMART Domains

Protein: ENSMUSP00000137592
Gene: ENSMUSG00000030655

Domain	Start	End	E-Value	Type
low complexity region	18	31	N/A	INTRINSIC
SCOP:d1gw5a_	71	545	1e-6	SMART
low complexity region	602	612	N/A	INTRINSIC
low complexity region	631	646	N/A	INTRINSIC
low complexity region	698	718	N/A	INTRINSIC
low complexity region	898	915	N/A	INTRINSIC
low complexity region	1135	1147	N/A	INTRINSIC
low complexity region	1464	1475	N/A	INTRINSIC
low complexity region	2049	2065	N/A	INTRINSIC
PI3Kc	2073	2417	7.93e-50	SMART
low complexity region	2683	2694	N/A	INTRINSIC
low complexity region	3349	3366	N/A	INTRINSIC
FATC	3550	3582	8.66e-12	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000208025

Coding Region Coverage

1x: 97.3%
3x: 96.8%
10x: 95.4%
20x: 93.0%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit early embryonic lethality. Mice heteroygous for a gene trap allele exhibit abnormal tooth development, chronic inflammation, increased body weight, increased incidence of tumor formation and premature death. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 83 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca8b	C	A	11: 109,847,924 (GRCm39)	L852F	possibly damaging	Het
Abcc6	T	C	7: 45,669,558 (GRCm39)		probably null	Het
Alg11	T	G	8: 22,555,584 (GRCm39)	C240G	probably damaging	Het
Aox1	A	G	1: 58,141,783 (GRCm39)	I1190V	probably damaging	Het
Apc2	T	G	10: 80,150,678 (GRCm39)	S1911A	probably benign	Het
Arfgef3	T	C	10: 18,528,511 (GRCm39)	D292G	possibly damaging	Het
Arhgef4	C	A	1: 34,763,340 (GRCm39)	S865R	probably benign	Het
Ass1	T	A	2: 31,383,160 (GRCm39)	Y190*	probably null	Het
B4galnt3	A	T	6: 120,187,051 (GRCm39)		probably null	Het
Btnl10	C	A	11: 58,811,367 (GRCm39)	P230Q	possibly damaging	Het
C3	A	G	17: 57,516,489 (GRCm39)	Y1348H	probably damaging	Het
Ccdc198	G	T	14: 49,464,032 (GRCm39)	D292E	probably damaging	Het
Cebpz	A	T	17: 79,242,336 (GRCm39)	Y439*	probably null	Het
Cic	C	A	7: 24,986,265 (GRCm39)	T1229K	probably damaging	Het
Clip4	T	C	17: 72,144,744 (GRCm39)	S524P	probably damaging	Het
Col6a3	A	C	1: 90,739,421 (GRCm39)	I269R	probably damaging	Het
Dbh	C	T	2: 27,071,506 (GRCm39)	T533I	possibly damaging	Het
Dcaf17	A	T	2: 70,890,713 (GRCm39)	R83*	probably null	Het
Dennd2b	G	A	7: 109,124,533 (GRCm39)	Q686*	probably null	Het
Dnah1	A	G	14: 30,984,515 (GRCm39)	L3923P	probably damaging	Het
Dnah7a	A	T	1: 53,670,721 (GRCm39)	D510E	probably benign	Het
Dock6	A	G	9: 21,752,925 (GRCm39)	F296S	probably damaging	Het
Eif4enif1	T	C	11: 3,177,455 (GRCm39)	S341P	probably damaging	Het
Epb41l1	G	T	2: 156,352,737 (GRCm39)	G461V	possibly damaging	Het
Epg5	T	A	18: 78,002,247 (GRCm39)	D555E	probably benign	Het
Fes	T	C	7: 80,036,609 (GRCm39)	R113G	probably damaging	Het
Garre1	T	A	7: 33,957,461 (GRCm39)	I59L	probably benign	Het
Gm10684	A	G	9: 45,021,511 (GRCm39)		probably benign	Het
Gm12185	T	C	11: 48,806,231 (GRCm39)	E320G	probably benign	Het
Gm14412	G	T	2: 177,007,269 (GRCm39)	H209N	probably damaging	Het
Gm14412	A	C	2: 177,007,630 (GRCm39)	S88R	probably benign	Het
Grhl1	T	A	12: 24,658,555 (GRCm39)	L400Q	probably damaging	Het
Havcr1	T	A	11: 46,664,511 (GRCm39)	Y216*	probably null	Het
Hephl1	A	C	9: 14,985,420 (GRCm39)	Y745*	probably null	Het
Hmcn2	T	G	2: 31,301,922 (GRCm39)		probably null	Het
Hs3st6	A	G	17: 24,977,110 (GRCm39)	K197E	possibly damaging	Het
Ifi214	C	T	1: 173,357,077 (GRCm39)	V9I	probably benign	Het
Jakmip2	T	C	18: 43,700,209 (GRCm39)	T450A	probably benign	Het
Lrp4	T	A	2: 91,328,753 (GRCm39)	V1551D	possibly damaging	Het
Macf1	A	T	4: 123,351,634 (GRCm39)	H1634Q	possibly damaging	Het
Mcpt8	T	A	14: 56,321,291 (GRCm39)	I58F	probably benign	Het
Mga	T	A	2: 119,757,075 (GRCm39)	H1018Q	possibly damaging	Het
Myo10	T	A	15: 25,801,308 (GRCm39)	V1499E	probably damaging	Het
Myom2	G	T	8: 15,131,023 (GRCm39)	D320Y	probably damaging	Het
Or11g7	T	A	14: 50,691,295 (GRCm39)	M262K	probably damaging	Het
Or13a27	T	C	7: 139,925,378 (GRCm39)	I175V	probably benign	Het
Or2r11	C	T	6: 42,437,360 (GRCm39)	V198M	probably benign	Het
Or2t26	A	C	11: 49,039,101 (GRCm39)	N6H	possibly damaging	Het
Or4c115	G	A	2: 88,927,888 (GRCm39)	P128S	probably damaging	Het
Or5d47	A	T	2: 87,804,403 (GRCm39)	V202D	possibly damaging	Het
Pabpc4	G	T	4: 123,182,861 (GRCm39)	R166L	possibly damaging	Het
Pcdhb8	A	G	18: 37,489,015 (GRCm39)	E231G	possibly damaging	Het
Pomgnt2	A	T	9: 121,811,257 (GRCm39)	I508N	possibly damaging	Het
Ppp2r5e	C	G	12: 75,516,341 (GRCm39)	A239P	probably damaging	Het
Prdm15	G	T	16: 97,638,885 (GRCm39)	D58E	probably benign	Het
Rgl2	A	G	17: 34,151,122 (GRCm39)	T117A	probably benign	Het
Rp1	A	G	1: 4,418,943 (GRCm39)	I723T	probably damaging	Het
Serpina3g	A	G	12: 104,207,536 (GRCm39)	E233G	probably damaging	Het
Skint6	T	A	4: 112,749,187 (GRCm39)	S798C	probably benign	Het
Slc35f1	T	C	10: 52,898,000 (GRCm39)	L137P	possibly damaging	Het
Slc6a20a	T	C	9: 123,485,373 (GRCm39)	N246S	probably damaging	Het
Slc7a2	T	C	8: 41,369,534 (GRCm39)	L663S	probably benign	Het
Slco1a4	A	G	6: 141,761,173 (GRCm39)		probably null	Het
Slit2	A	G	5: 48,439,330 (GRCm39)	T41A	probably damaging	Het
Smc2	T	C	4: 52,450,863 (GRCm39)	I227T	probably damaging	Het
Ssu2	A	T	6: 112,361,388 (GRCm39)	L23M	probably benign	Het
Syne2	A	G	12: 76,141,053 (GRCm39)		probably null	Het
Tekt1	T	C	11: 72,242,761 (GRCm39)	T249A	probably benign	Het
Tfr2	T	C	5: 137,569,954 (GRCm39)	V120A	probably benign	Het
Thsd7b	C	T	1: 129,605,846 (GRCm39)	P529L	probably damaging	Het
Tll1	C	T	8: 64,478,141 (GRCm39)	D871N	probably damaging	Het
Tlr11	A	C	14: 50,598,664 (GRCm39)	I217L	probably benign	Het
Tmem87b	T	A	2: 128,673,479 (GRCm39)	V241D	probably damaging	Het
Tshz2	T	A	2: 169,727,465 (GRCm39)	I218N	possibly damaging	Het
Vmn1r18	A	T	6: 57,367,026 (GRCm39)	I176N	possibly damaging	Het
Vmn2r68	T	A	7: 84,883,260 (GRCm39)	H164L	probably benign	Het
Vmn2r74	T	C	7: 85,601,650 (GRCm39)	T663A	probably benign	Het
Vmn2r8	T	C	5: 108,945,436 (GRCm39)	T724A	probably benign	Het
Wdr11	T	C	7: 129,206,954 (GRCm39)	V289A	possibly damaging	Het
Zfp62	T	A	11: 49,107,047 (GRCm39)	D379E	probably damaging	Het
Zfp78	C	T	7: 6,381,897 (GRCm39)	P316S	probably damaging	Het
Zfyve27	T	G	19: 42,159,987 (GRCm39)	M1R	probably null	Het
Zkscan8	G	A	13: 21,709,325 (GRCm39)	P191L	probably damaging	Het

Other mutations in Smg1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00272:Smg1	APN	7	117,797,494 (GRCm39)	utr 3 prime	probably benign
IGL00481:Smg1	APN	7	117,810,017 (GRCm39)	missense	possibly damaging	0.67
IGL00503:Smg1	APN	7	117,784,706 (GRCm39)	utr 3 prime	probably benign
IGL00927:Smg1	APN	7	117,739,855 (GRCm39)	missense	probably damaging	1.00
IGL01333:Smg1	APN	7	117,762,601 (GRCm39)	splice site	probably benign
IGL01344:Smg1	APN	7	117,790,059 (GRCm39)	utr 3 prime	probably benign
IGL01397:Smg1	APN	7	117,762,444 (GRCm39)	utr 3 prime	probably benign
IGL01403:Smg1	APN	7	117,757,355 (GRCm39)	utr 3 prime	probably benign
IGL01573:Smg1	APN	7	117,767,185 (GRCm39)	utr 3 prime	probably benign
IGL01872:Smg1	APN	7	117,748,167 (GRCm39)	utr 3 prime	probably benign
IGL02010:Smg1	APN	7	117,785,369 (GRCm39)	utr 3 prime	probably benign
IGL02158:Smg1	APN	7	117,812,169 (GRCm39)	missense	possibly damaging	0.77
IGL02268:Smg1	APN	7	117,781,764 (GRCm39)	missense	probably benign	0.19
IGL02314:Smg1	APN	7	117,753,932 (GRCm39)	utr 3 prime	probably benign
IGL02552:Smg1	APN	7	117,795,117 (GRCm39)	utr 3 prime	probably benign
IGL02577:Smg1	APN	7	117,802,345 (GRCm39)	missense	probably damaging	0.99
IGL02859:Smg1	APN	7	117,748,156 (GRCm39)	utr 3 prime	probably benign
IGL02890:Smg1	APN	7	117,784,724 (GRCm39)	utr 3 prime	probably benign
IGL02892:Smg1	APN	7	117,767,178 (GRCm39)	utr 3 prime	probably benign
IGL03119:Smg1	APN	7	117,794,336 (GRCm39)	utr 3 prime	probably benign
IGL03123:Smg1	APN	7	117,756,404 (GRCm39)	utr 3 prime	probably benign
IGL03128:Smg1	APN	7	117,802,282 (GRCm39)	missense	probably benign	0.03
IGL03184:Smg1	APN	7	117,779,603 (GRCm39)	missense	possibly damaging	0.86
PIT4508001:Smg1	UTSW	7	117,784,764 (GRCm39)	missense	unknown
R0010:Smg1	UTSW	7	117,771,082 (GRCm39)	utr 3 prime	probably benign
R0010:Smg1	UTSW	7	117,771,082 (GRCm39)	utr 3 prime	probably benign
R0025:Smg1	UTSW	7	117,811,666 (GRCm39)	missense	possibly damaging	0.92
R0025:Smg1	UTSW	7	117,811,666 (GRCm39)	missense	possibly damaging	0.92
R0098:Smg1	UTSW	7	117,744,690 (GRCm39)	missense	probably benign	0.02
R0139:Smg1	UTSW	7	117,751,898 (GRCm39)	critical splice donor site	probably null
R0371:Smg1	UTSW	7	117,767,523 (GRCm39)	utr 3 prime	probably benign
R0415:Smg1	UTSW	7	117,781,691 (GRCm39)	missense	probably benign	0.34
R0416:Smg1	UTSW	7	117,783,684 (GRCm39)	splice site	probably benign
R0423:Smg1	UTSW	7	117,776,103 (GRCm39)	missense	possibly damaging	0.53
R0600:Smg1	UTSW	7	117,759,606 (GRCm39)	utr 3 prime	probably benign
R0626:Smg1	UTSW	7	117,781,606 (GRCm39)	missense	possibly damaging	0.82
R0627:Smg1	UTSW	7	117,767,084 (GRCm39)	utr 3 prime	probably benign
R0727:Smg1	UTSW	7	117,765,645 (GRCm39)	utr 3 prime	probably benign
R0729:Smg1	UTSW	7	117,745,512 (GRCm39)	utr 3 prime	probably benign
R0841:Smg1	UTSW	7	117,742,524 (GRCm39)	missense	possibly damaging	0.96
R1114:Smg1	UTSW	7	117,759,013 (GRCm39)	utr 3 prime	probably benign
R1256:Smg1	UTSW	7	117,802,310 (GRCm39)	missense	probably damaging	1.00
R1298:Smg1	UTSW	7	117,767,434 (GRCm39)	utr 3 prime	probably benign
R1370:Smg1	UTSW	7	117,758,975 (GRCm39)	utr 3 prime	probably benign
R1591:Smg1	UTSW	7	117,756,142 (GRCm39)	utr 3 prime	probably benign
R1736:Smg1	UTSW	7	117,765,190 (GRCm39)	splice site	probably null
R1755:Smg1	UTSW	7	117,802,287 (GRCm39)	nonsense	probably null
R1765:Smg1	UTSW	7	117,738,938 (GRCm39)	missense	probably benign	0.03
R1789:Smg1	UTSW	7	117,745,021 (GRCm39)	missense	possibly damaging	0.73
R1845:Smg1	UTSW	7	117,753,845 (GRCm39)	utr 3 prime	probably benign
R1909:Smg1	UTSW	7	117,753,422 (GRCm39)	utr 3 prime	probably benign
R1942:Smg1	UTSW	7	117,757,326 (GRCm39)	utr 3 prime	probably benign
R2064:Smg1	UTSW	7	117,756,090 (GRCm39)	utr 3 prime	probably benign
R2072:Smg1	UTSW	7	117,762,389 (GRCm39)	utr 3 prime	probably benign
R2154:Smg1	UTSW	7	117,757,299 (GRCm39)	utr 3 prime	probably benign
R2895:Smg1	UTSW	7	117,788,366 (GRCm39)	utr 3 prime	probably benign
R2915:Smg1	UTSW	7	117,810,102 (GRCm39)	splice site	probably benign
R3416:Smg1	UTSW	7	117,748,076 (GRCm39)	utr 3 prime	probably benign
R3417:Smg1	UTSW	7	117,748,076 (GRCm39)	utr 3 prime	probably benign
R3873:Smg1	UTSW	7	117,753,885 (GRCm39)	utr 3 prime	probably benign
R4082:Smg1	UTSW	7	117,759,469 (GRCm39)	utr 3 prime	probably benign
R4230:Smg1	UTSW	7	117,747,956 (GRCm39)	critical splice donor site	probably null
R4304:Smg1	UTSW	7	117,738,741 (GRCm39)	missense	probably benign	0.03
R4549:Smg1	UTSW	7	117,758,906 (GRCm39)	utr 3 prime	probably benign
R4571:Smg1	UTSW	7	117,738,688 (GRCm39)	missense	possibly damaging	0.72
R4638:Smg1	UTSW	7	117,795,149 (GRCm39)	utr 3 prime	probably benign
R4642:Smg1	UTSW	7	117,753,487 (GRCm39)	utr 3 prime	probably benign
R4656:Smg1	UTSW	7	117,812,174 (GRCm39)	missense	probably benign	0.00
R4754:Smg1	UTSW	7	117,755,954 (GRCm39)	utr 3 prime	probably benign
R4798:Smg1	UTSW	7	117,779,697 (GRCm39)	missense	probably benign	0.32
R4906:Smg1	UTSW	7	117,751,631 (GRCm39)	utr 3 prime	probably benign
R4978:Smg1	UTSW	7	117,753,470 (GRCm39)	utr 3 prime	probably benign
R4989:Smg1	UTSW	7	117,807,274 (GRCm39)	missense	probably benign
R4989:Smg1	UTSW	7	117,757,323 (GRCm39)	utr 3 prime	probably benign
R5026:Smg1	UTSW	7	117,792,768 (GRCm39)	utr 3 prime	probably benign
R5124:Smg1	UTSW	7	117,812,235 (GRCm39)	missense	probably benign	0.00
R5318:Smg1	UTSW	7	117,759,427 (GRCm39)	utr 3 prime	probably benign
R5356:Smg1	UTSW	7	117,794,356 (GRCm39)	utr 3 prime	probably benign
R5404:Smg1	UTSW	7	117,806,131 (GRCm39)	missense	probably damaging	1.00
R5423:Smg1	UTSW	7	117,745,294 (GRCm39)	missense	possibly damaging	0.70
R5441:Smg1	UTSW	7	117,794,304 (GRCm39)	utr 3 prime	probably benign
R5490:Smg1	UTSW	7	117,738,659 (GRCm39)	missense	possibly damaging	0.86
R5541:Smg1	UTSW	7	117,756,386 (GRCm39)	utr 3 prime	probably benign
R5564:Smg1	UTSW	7	117,789,042 (GRCm39)	utr 3 prime	probably benign
R5580:Smg1	UTSW	7	117,748,125 (GRCm39)	utr 3 prime	probably benign
R5600:Smg1	UTSW	7	117,767,107 (GRCm39)	utr 3 prime	probably benign
R5628:Smg1	UTSW	7	117,753,924 (GRCm39)	utr 3 prime	probably benign
R5646:Smg1	UTSW	7	117,811,782 (GRCm39)	missense	probably benign	0.42
R5656:Smg1	UTSW	7	117,753,887 (GRCm39)	utr 3 prime	probably benign
R5660:Smg1	UTSW	7	117,742,570 (GRCm39)	missense	probably benign	0.33
R5706:Smg1	UTSW	7	117,744,813 (GRCm39)	missense	possibly damaging	0.86
R5786:Smg1	UTSW	7	117,812,120 (GRCm39)	missense	probably benign	0.12
R5890:Smg1	UTSW	7	117,789,809 (GRCm39)	utr 3 prime	probably benign
R5912:Smg1	UTSW	7	117,753,809 (GRCm39)	utr 3 prime	probably benign
R5977:Smg1	UTSW	7	117,740,580 (GRCm39)	utr 3 prime	probably benign
R5993:Smg1	UTSW	7	117,739,732 (GRCm39)	missense	probably benign	0.33
R6161:Smg1	UTSW	7	117,762,553 (GRCm39)	utr 3 prime	probably benign
R6187:Smg1	UTSW	7	117,788,386 (GRCm39)	utr 3 prime	probably benign
R6264:Smg1	UTSW	7	117,765,310 (GRCm39)	utr 3 prime	probably benign
R6331:Smg1	UTSW	7	117,753,500 (GRCm39)	utr 3 prime	probably benign
R6561:Smg1	UTSW	7	117,765,300 (GRCm39)	utr 3 prime	probably benign
R6571:Smg1	UTSW	7	117,783,737 (GRCm39)	utr 3 prime	probably benign
R6736:Smg1	UTSW	7	117,756,389 (GRCm39)	utr 3 prime	probably benign
R6752:Smg1	UTSW	7	117,762,539 (GRCm39)	utr 3 prime	probably benign
R6777:Smg1	UTSW	7	117,788,340 (GRCm39)	utr 3 prime	probably benign
R6788:Smg1	UTSW	7	117,783,794 (GRCm39)	utr 3 prime	probably benign
R6883:Smg1	UTSW	7	117,767,403 (GRCm39)	utr 3 prime	probably benign
R6991:Smg1	UTSW	7	117,767,091 (GRCm39)	utr 3 prime	probably benign
R7056:Smg1	UTSW	7	117,745,623 (GRCm39)	splice site	probably benign
R7058:Smg1	UTSW	7	117,797,502 (GRCm39)	utr 3 prime	probably benign
R7100:Smg1	UTSW	7	117,783,743 (GRCm39)	missense	unknown
R7133:Smg1	UTSW	7	117,752,131 (GRCm39)	missense	unknown
R7221:Smg1	UTSW	7	117,782,020 (GRCm39)	missense	possibly damaging	0.86
R7229:Smg1	UTSW	7	117,776,178 (GRCm39)	missense	probably benign	0.03
R7293:Smg1	UTSW	7	117,765,322 (GRCm39)	missense	unknown
R7361:Smg1	UTSW	7	117,784,200 (GRCm39)	missense	unknown
R7438:Smg1	UTSW	7	117,795,116 (GRCm39)	missense	unknown
R7686:Smg1	UTSW	7	117,767,081 (GRCm39)	missense	unknown
R7798:Smg1	UTSW	7	117,771,162 (GRCm39)	missense	possibly damaging	0.73
R7908:Smg1	UTSW	7	117,785,357 (GRCm39)	missense	unknown
R7923:Smg1	UTSW	7	117,742,545 (GRCm39)	missense	possibly damaging	0.96
R7978:Smg1	UTSW	7	117,792,878 (GRCm39)	missense	unknown
R7997:Smg1	UTSW	7	117,772,365 (GRCm39)	missense	unknown
R7997:Smg1	UTSW	7	117,772,364 (GRCm39)	missense	unknown
R8025:Smg1	UTSW	7	117,806,212 (GRCm39)	nonsense	probably null
R8056:Smg1	UTSW	7	117,759,589 (GRCm39)	missense	unknown
R8061:Smg1	UTSW	7	117,751,610 (GRCm39)	missense	unknown
R8095:Smg1	UTSW	7	117,772,285 (GRCm39)	missense	unknown
R8198:Smg1	UTSW	7	117,744,829 (GRCm39)	missense	probably benign	0.03
R8399:Smg1	UTSW	7	117,789,794 (GRCm39)	missense	unknown
R8445:Smg1	UTSW	7	117,736,200 (GRCm39)	missense	possibly damaging	0.72
R8519:Smg1	UTSW	7	117,770,982 (GRCm39)	utr 3 prime	probably benign
R8817:Smg1	UTSW	7	117,758,887 (GRCm39)	missense	unknown
R8832:Smg1	UTSW	7	117,739,006 (GRCm39)	missense	probably benign	0.33
R8855:Smg1	UTSW	7	117,806,122 (GRCm39)	missense	unknown
R8866:Smg1	UTSW	7	117,806,122 (GRCm39)	missense	unknown
R8946:Smg1	UTSW	7	117,751,900 (GRCm39)	missense	probably null
R8954:Smg1	UTSW	7	117,806,215 (GRCm39)	missense	probably damaging	1.00
R8967:Smg1	UTSW	7	117,765,739 (GRCm39)	missense	unknown
R9072:Smg1	UTSW	7	117,783,032 (GRCm39)	missense	unknown
R9090:Smg1	UTSW	7	117,811,786 (GRCm39)	missense	unknown
R9156:Smg1	UTSW	7	117,753,884 (GRCm39)	missense	unknown
R9198:Smg1	UTSW	7	117,795,179 (GRCm39)	missense	unknown
R9240:Smg1	UTSW	7	117,739,031 (GRCm39)	missense	probably benign	0.18
R9271:Smg1	UTSW	7	117,811,786 (GRCm39)	missense	unknown
R9289:Smg1	UTSW	7	117,744,639 (GRCm39)	missense	possibly damaging	0.53
R9378:Smg1	UTSW	7	117,777,998 (GRCm39)	nonsense	probably null
R9396:Smg1	UTSW	7	117,807,303 (GRCm39)	missense	unknown
R9469:Smg1	UTSW	7	117,739,774 (GRCm39)	missense	possibly damaging	0.72
R9539:Smg1	UTSW	7	117,744,976 (GRCm39)	missense	probably benign	0.03
R9549:Smg1	UTSW	7	117,795,254 (GRCm39)	missense	unknown
R9563:Smg1	UTSW	7	117,812,208 (GRCm39)	missense	unknown
R9564:Smg1	UTSW	7	117,812,208 (GRCm39)	missense	unknown
R9597:Smg1	UTSW	7	117,812,270 (GRCm39)	missense	unknown
R9643:Smg1	UTSW	7	117,755,933 (GRCm39)	missense	unknown
R9703:Smg1	UTSW	7	117,739,744 (GRCm39)	missense	possibly damaging	0.73
R9730:Smg1	UTSW	7	117,783,004 (GRCm39)	missense	unknown
Z1088:Smg1	UTSW	7	117,777,622 (GRCm39)	missense	possibly damaging	0.96
Z1088:Smg1	UTSW	7	117,767,884 (GRCm39)	nonsense	probably null
Z1088:Smg1	UTSW	7	117,753,858 (GRCm39)	utr 3 prime	probably benign
Z1176:Smg1	UTSW	7	117,806,130 (GRCm39)	missense	unknown
Z1176:Smg1	UTSW	7	117,806,110 (GRCm39)	missense	unknown
Z1177:Smg1	UTSW	7	117,812,256 (GRCm39)	missense	unknown
Z1177:Smg1	UTSW	7	117,767,831 (GRCm39)	missense	probably null

Predicted Primers

PCR Primer
(F):5'- AGGTACTTCACTGAAATTTCATCTG -3'
(R):5'- CAGCCAGTGTGAGCAGCTAG -3'

Sequencing Primer
(F):5'- CCAGATTGCCTGCCTGTAAAGATG -3'
(R):5'- GAGGGGGAAGTTGGCGCTC -3'

Posted On

2014-06-30