Incidental Mutation 'R1909:Dip2c'
| ID |
210201 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| MMRRC Submission |
039928-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.589)
|
| Stock # |
R1909 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
9326564-9718964 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 9583386 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Serine
at position 123
(T123S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133806
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166299
AA Change: T123S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: T123S
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000169960
AA Change: T179S
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: T179S
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000174552
AA Change: T123S
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: T123S
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 93.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 112 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
A |
C |
11: 101,301,057 (GRCm39) |
|
probably null |
Het |
| Abcc5 |
A |
G |
16: 20,195,259 (GRCm39) |
|
probably null |
Het |
| Abcc6 |
T |
C |
7: 45,669,558 (GRCm39) |
|
probably null |
Het |
| Adam15 |
C |
A |
3: 89,252,637 (GRCm39) |
M317I |
probably benign |
Het |
| Ago3 |
T |
C |
4: 126,240,530 (GRCm39) |
T111A |
probably damaging |
Het |
| Amz1 |
G |
T |
5: 140,738,216 (GRCm39) |
S492I |
probably benign |
Het |
| Arid1a |
T |
C |
4: 133,421,072 (GRCm39) |
N911S |
unknown |
Het |
| Ascl2 |
C |
A |
7: 142,521,900 (GRCm39) |
A115S |
probably damaging |
Het |
| Ash1l |
T |
C |
3: 88,891,835 (GRCm39) |
V1238A |
probably benign |
Het |
| Asxl2 |
G |
T |
12: 3,524,577 (GRCm39) |
V202F |
probably damaging |
Het |
| Atp10a |
A |
T |
7: 58,478,460 (GRCm39) |
Q1501L |
probably benign |
Het |
| Avpr1a |
A |
T |
10: 122,288,113 (GRCm39) |
I374L |
probably benign |
Het |
| Bmal2 |
A |
T |
6: 146,712,308 (GRCm39) |
E111V |
probably benign |
Het |
| Bmx |
T |
C |
X: 163,022,411 (GRCm39) |
H157R |
probably benign |
Het |
| Camk4 |
T |
A |
18: 33,291,869 (GRCm39) |
|
probably null |
Het |
| Ccdc103 |
G |
A |
11: 102,773,392 (GRCm39) |
D5N |
probably benign |
Het |
| Ccdc186 |
A |
T |
19: 56,781,793 (GRCm39) |
N70K |
probably damaging |
Het |
| Cebpz |
A |
T |
17: 79,242,336 (GRCm39) |
Y439* |
probably null |
Het |
| Cfap206 |
A |
C |
4: 34,722,714 (GRCm39) |
S122R |
probably benign |
Het |
| Cnst |
T |
C |
1: 179,450,356 (GRCm39) |
S607P |
probably damaging |
Het |
| Col8a2 |
C |
A |
4: 126,205,926 (GRCm39) |
D645E |
possibly damaging |
Het |
| Cpsf4l |
A |
T |
11: 113,594,204 (GRCm39) |
|
probably null |
Het |
| Crim1 |
C |
T |
17: 78,620,556 (GRCm39) |
T332I |
probably benign |
Het |
| Csmd1 |
A |
T |
8: 15,956,116 (GRCm39) |
Y3364N |
probably damaging |
Het |
| D5Ertd579e |
A |
T |
5: 36,771,402 (GRCm39) |
S998T |
probably benign |
Het |
| Dab2ip |
C |
G |
2: 35,608,827 (GRCm39) |
A587G |
probably damaging |
Het |
| Dach1 |
C |
T |
14: 98,138,829 (GRCm39) |
G486D |
probably damaging |
Het |
| Ddx24 |
T |
C |
12: 103,376,241 (GRCm39) |
I752V |
probably damaging |
Het |
| Dennd2b |
G |
A |
7: 109,124,533 (GRCm39) |
Q686* |
probably null |
Het |
| Dhx33 |
A |
G |
11: 70,879,933 (GRCm39) |
V359A |
probably benign |
Het |
| Dync1h1 |
G |
A |
12: 110,629,063 (GRCm39) |
E4207K |
probably damaging |
Het |
| Eef1b2 |
G |
T |
1: 63,216,431 (GRCm39) |
D21Y |
probably damaging |
Het |
| Eif3b |
T |
C |
5: 140,418,692 (GRCm39) |
S462P |
probably damaging |
Het |
| Elmod2 |
G |
C |
8: 84,042,998 (GRCm39) |
R277G |
probably benign |
Het |
| Epg5 |
T |
A |
18: 78,002,247 (GRCm39) |
D555E |
probably benign |
Het |
| Ercc8 |
A |
T |
13: 108,312,100 (GRCm39) |
K172* |
probably null |
Het |
| Fat3 |
T |
C |
9: 15,909,411 (GRCm39) |
N2197S |
probably benign |
Het |
| Fbf1 |
A |
G |
11: 116,036,818 (GRCm39) |
V972A |
possibly damaging |
Het |
| Fcgbpl1 |
T |
C |
7: 27,843,773 (GRCm39) |
V887A |
possibly damaging |
Het |
| Fes |
T |
C |
7: 80,036,609 (GRCm39) |
R113G |
probably damaging |
Het |
| Fzd1 |
G |
T |
5: 4,807,481 (GRCm39) |
H34N |
probably benign |
Het |
| Galnt17 |
T |
A |
5: 131,140,676 (GRCm39) |
Y147F |
probably benign |
Het |
| Garre1 |
T |
A |
7: 33,957,461 (GRCm39) |
I59L |
probably benign |
Het |
| Gdf6 |
T |
C |
4: 9,859,971 (GRCm39) |
L351P |
probably damaging |
Het |
| Gm10277 |
TC |
T |
11: 77,676,828 (GRCm39) |
|
probably null |
Het |
| Gm2381 |
A |
T |
7: 42,469,352 (GRCm39) |
H257Q |
probably damaging |
Het |
| Hivep1 |
A |
T |
13: 42,309,122 (GRCm39) |
K454M |
probably benign |
Het |
| Hmmr |
T |
A |
11: 40,598,925 (GRCm39) |
E566D |
probably damaging |
Het |
| Hydin |
T |
G |
8: 111,314,404 (GRCm39) |
V4296G |
probably damaging |
Het |
| Il18r1 |
T |
A |
1: 40,514,074 (GRCm39) |
D93E |
probably damaging |
Het |
| Iqgap1 |
T |
C |
7: 80,393,576 (GRCm39) |
D667G |
probably benign |
Het |
| Lama3 |
T |
C |
18: 12,714,855 (GRCm39) |
I3278T |
probably benign |
Het |
| Lrp4 |
T |
A |
2: 91,328,753 (GRCm39) |
V1551D |
possibly damaging |
Het |
| Mdn1 |
CGGAGGAGGAGGAGGAG |
CGGAGGAGGAGGAG |
4: 32,760,839 (GRCm39) |
|
probably benign |
Het |
| Mga |
T |
A |
2: 119,757,075 (GRCm39) |
H1018Q |
possibly damaging |
Het |
| Ncoa7 |
A |
T |
10: 30,565,796 (GRCm39) |
M666K |
probably damaging |
Het |
| Ndnf |
T |
G |
6: 65,680,297 (GRCm39) |
V192G |
possibly damaging |
Het |
| Nr4a1 |
T |
A |
15: 101,172,108 (GRCm39) |
I594N |
probably damaging |
Het |
| Or13a27 |
T |
C |
7: 139,925,378 (GRCm39) |
I175V |
probably benign |
Het |
| Or2ag16 |
T |
C |
7: 106,352,202 (GRCm39) |
N131S |
probably benign |
Het |
| Or4k44 |
T |
A |
2: 111,368,359 (GRCm39) |
I92F |
probably damaging |
Het |
| Or51q1 |
G |
A |
7: 103,628,997 (GRCm39) |
W199* |
probably null |
Het |
| Or52z13 |
A |
G |
7: 103,246,550 (GRCm39) |
N9S |
probably benign |
Het |
| Paxbp1 |
T |
C |
16: 90,841,193 (GRCm39) |
|
probably benign |
Het |
| Pcdhb8 |
A |
G |
18: 37,489,015 (GRCm39) |
E231G |
possibly damaging |
Het |
| Pcsk5 |
A |
T |
19: 17,410,825 (GRCm39) |
Y1856N |
probably benign |
Het |
| Pde3a |
T |
C |
6: 141,195,965 (GRCm39) |
V217A |
probably benign |
Het |
| Phf11 |
A |
T |
14: 59,496,062 (GRCm39) |
S17R |
probably benign |
Het |
| Pira13 |
A |
T |
7: 3,825,918 (GRCm39) |
I317N |
probably benign |
Het |
| Pirb |
A |
T |
7: 3,717,587 (GRCm39) |
D674E |
probably benign |
Het |
| Pnisr |
T |
A |
4: 21,869,517 (GRCm39) |
M335K |
possibly damaging |
Het |
| Pnpla7 |
T |
A |
2: 24,887,300 (GRCm39) |
M48K |
possibly damaging |
Het |
| Pomgnt2 |
A |
T |
9: 121,811,257 (GRCm39) |
I508N |
possibly damaging |
Het |
| Ppp2r5e |
C |
G |
12: 75,516,341 (GRCm39) |
A239P |
probably damaging |
Het |
| Prkca |
A |
T |
11: 107,830,438 (GRCm39) |
D217E |
possibly damaging |
Het |
| Rac3 |
A |
C |
11: 120,614,163 (GRCm39) |
I142L |
probably benign |
Het |
| Ralgapb |
G |
T |
2: 158,286,595 (GRCm39) |
A347S |
probably damaging |
Het |
| Rbm43 |
G |
C |
2: 51,815,446 (GRCm39) |
S258R |
possibly damaging |
Het |
| Rnf182 |
T |
A |
13: 43,821,899 (GRCm39) |
V150E |
probably benign |
Het |
| Rsph10b |
T |
C |
5: 143,922,309 (GRCm39) |
F409L |
probably benign |
Het |
| Ryr2 |
A |
T |
13: 11,715,235 (GRCm39) |
L2778M |
probably damaging |
Het |
| Scn1a |
T |
C |
2: 66,161,696 (GRCm39) |
N284S |
possibly damaging |
Het |
| Scyl2 |
A |
T |
10: 89,476,767 (GRCm39) |
M786K |
probably benign |
Het |
| Sema4g |
C |
A |
19: 44,986,061 (GRCm39) |
R301S |
probably damaging |
Het |
| Senp6 |
A |
T |
9: 80,021,056 (GRCm39) |
E245D |
possibly damaging |
Het |
| Setx |
T |
C |
2: 29,053,021 (GRCm39) |
V2095A |
possibly damaging |
Het |
| Slc13a2 |
A |
T |
11: 78,290,968 (GRCm39) |
M412K |
possibly damaging |
Het |
| Slc25a4 |
T |
C |
8: 46,662,437 (GRCm39) |
N74D |
probably damaging |
Het |
| Slc28a1 |
T |
A |
7: 80,791,783 (GRCm39) |
F316L |
probably damaging |
Het |
| Slfn8 |
G |
A |
11: 82,894,447 (GRCm39) |
Q731* |
probably null |
Het |
| Slitrk4 |
A |
G |
X: 63,316,229 (GRCm39) |
I146T |
probably damaging |
Het |
| Smg1 |
A |
G |
7: 117,753,422 (GRCm39) |
|
probably benign |
Het |
| Smg8 |
G |
T |
11: 86,971,439 (GRCm39) |
Y777* |
probably null |
Het |
| Smyd1 |
T |
A |
6: 71,216,563 (GRCm39) |
K61N |
probably benign |
Het |
| Sod2 |
T |
C |
17: 13,234,056 (GRCm39) |
*223R |
probably null |
Het |
| Sp6 |
G |
T |
11: 96,912,334 (GRCm39) |
A16S |
probably benign |
Het |
| Spata31d1a |
A |
C |
13: 59,850,509 (GRCm39) |
Y540D |
probably damaging |
Het |
| Spatc1l |
A |
G |
10: 76,399,751 (GRCm39) |
D91G |
probably damaging |
Het |
| Spg7 |
A |
G |
8: 123,807,480 (GRCm39) |
T419A |
probably benign |
Het |
| St8sia4 |
A |
G |
1: 95,555,298 (GRCm39) |
I244T |
probably damaging |
Het |
| Tbl2 |
C |
T |
5: 135,181,845 (GRCm39) |
R27W |
probably damaging |
Het |
| Tmed4 |
G |
A |
11: 6,224,694 (GRCm39) |
P47L |
probably damaging |
Het |
| Tmsb10b |
T |
C |
7: 24,561,731 (GRCm39) |
I10T |
possibly damaging |
Het |
| Tmtc1 |
T |
C |
6: 148,345,546 (GRCm39) |
D51G |
possibly damaging |
Het |
| Ttc28 |
T |
C |
5: 111,431,920 (GRCm39) |
|
probably null |
Het |
| Unc13d |
A |
G |
11: 115,961,121 (GRCm39) |
F412S |
probably damaging |
Het |
| Unc45b |
A |
C |
11: 82,816,913 (GRCm39) |
K451T |
probably damaging |
Het |
| Vmn2r16 |
A |
G |
5: 109,511,853 (GRCm39) |
M687V |
probably benign |
Het |
| Vmn2r68 |
T |
A |
7: 84,883,260 (GRCm39) |
H164L |
probably benign |
Het |
| Vps51 |
A |
G |
19: 6,119,499 (GRCm39) |
V625A |
probably benign |
Het |
| Wapl |
T |
A |
14: 34,413,869 (GRCm39) |
W244R |
probably damaging |
Het |
| Wdr75 |
C |
T |
1: 45,862,563 (GRCm39) |
T794I |
probably benign |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,543,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,656,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,617,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,660,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,687,124 (GRCm39) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,603,303 (GRCm39) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,672,666 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,556,695 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,656,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,660,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,600,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,660,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,712,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,697,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,671,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,687,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,665,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,654,635 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,618,325 (GRCm39) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,613,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,603,495 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,618,699 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,684,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,543,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,603,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,601,902 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,715,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,709,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,625,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,671,985 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2013:Dip2c
|
UTSW |
13 |
9,617,882 (GRCm39) |
nonsense |
probably null |
|
|
R2022:Dip2c
|
UTSW |
13 |
9,601,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2517:Dip2c
|
UTSW |
13 |
9,659,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,651,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,654,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,601,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,664,401 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,659,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,660,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,621,098 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4739:Dip2c
|
UTSW |
13 |
9,583,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4812:Dip2c
|
UTSW |
13 |
9,687,166 (GRCm39) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,586,896 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,625,186 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,610,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4932:Dip2c
|
UTSW |
13 |
9,674,008 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4993:Dip2c
|
UTSW |
13 |
9,625,259 (GRCm39) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,601,863 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,672,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,618,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,556,712 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,673,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,583,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,697,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,673,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,625,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,704,624 (GRCm39) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,543,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,617,866 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,671,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,684,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,601,896 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,709,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,660,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,654,572 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,556,684 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,642,785 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7395:Dip2c
|
UTSW |
13 |
9,664,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7489:Dip2c
|
UTSW |
13 |
9,583,348 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,678,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,672,741 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,654,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7699:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,664,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,656,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,659,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,671,918 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,687,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,660,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,665,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,673,834 (GRCm39) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,625,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,625,503 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,625,182 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,673,989 (GRCm39) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,673,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,660,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,709,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,544,963 (GRCm39) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,544,875 (GRCm39) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,704,683 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,625,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,626,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAACGACTGCTTTCCTTTACC -3'
(R):5'- CATGTGCAAATGCTGTGATTG -3'
Sequencing Primer
(F):5'- TCTGAGCTTAGGTACAAAGTCC -3'
(R):5'- TGCAAATGCTGTGATTGAAAGCC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation