Incidental Mutation 'R1912:Igsf10'
| ID |
210355 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Igsf10
|
| Ensembl Gene |
ENSMUSG00000036334 |
| Gene Name |
immunoglobulin superfamily, member 10 |
| Synonyms |
Adlican2, CMF608, 6530405F15Rik |
| MMRRC Submission |
039930-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.279)
|
| Stock # |
R1912 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
59316735-59344394 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 59329572 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Proline
at position 1063
(T1063P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000141391
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039419]
[ENSMUST00000193455]
[ENSMUST00000194546]
|
| AlphaFold |
Q3V1M1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000039419
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000037246
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193455
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000141971
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194546
AA Change: T1063P
PolyPhen 2
Score 0.403 (Sensitivity: 0.89; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000141391
Gene: ENSMUSG00000036334
AA Change: T1063P
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
LRRNT
|
28 |
61 |
3.24e-4 |
SMART |
|
LRR
|
57 |
79 |
9.24e1 |
SMART |
|
LRR
|
80 |
103 |
2.02e-1 |
SMART |
|
LRR
|
104 |
127 |
7.16e0 |
SMART |
|
LRR_TYP
|
128 |
151 |
1.2e-3 |
SMART |
|
LRR
|
152 |
175 |
1.25e-1 |
SMART |
|
LRR
|
188 |
207 |
2.33e2 |
SMART |
|
LRRCT
|
219 |
280 |
4.19e-4 |
SMART |
|
IGc2
|
488 |
558 |
2.34e-4 |
SMART |
|
IGc2
|
586 |
652 |
7.88e-11 |
SMART |
|
low complexity region
|
917 |
930 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1263 |
N/A |
INTRINSIC |
|
low complexity region
|
1311 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1449 |
1465 |
N/A |
INTRINSIC |
|
IGc2
|
1632 |
1701 |
7.69e-14 |
SMART |
|
IGc2
|
1729 |
1798 |
5.07e-14 |
SMART |
|
IGc2
|
1826 |
1895 |
2.19e-9 |
SMART |
|
IGc2
|
1925 |
1994 |
4.59e-12 |
SMART |
|
IGc2
|
2022 |
2097 |
1.33e-8 |
SMART |
|
IGc2
|
2125 |
2191 |
2.96e-15 |
SMART |
|
IGc2
|
2223 |
2291 |
2.03e-4 |
SMART |
|
IGc2
|
2321 |
2389 |
9.99e-13 |
SMART |
|
IGc2
|
2416 |
2484 |
3.03e-12 |
SMART |
|
IGc2
|
2512 |
2583 |
7.76e-10 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.3%
- 3x: 96.8%
- 10x: 95.3%
- 20x: 92.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 122 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700015F17Rik |
C |
A |
5: 5,452,019 (GRCm38) |
W144C |
probably benign |
Het |
| 2810474O19Rik |
T |
A |
6: 149,328,844 (GRCm38) |
D1129E |
possibly damaging |
Het |
| 2900092C05Rik |
A |
G |
7: 12,554,655 (GRCm38) |
M132V |
probably benign |
Het |
| 4921524L21Rik |
T |
A |
18: 6,620,205 (GRCm38) |
I45N |
possibly damaging |
Het |
| 9230113P08Rik |
A |
T |
9: 35,908,619 (GRCm38) |
T23S |
probably benign |
Het |
| Abcb6 |
A |
G |
1: 75,179,955 (GRCm38) |
V55A |
probably benign |
Het |
| Adam28 |
A |
T |
14: 68,644,331 (GRCm38) |
D105E |
probably benign |
Het |
| Ahnak |
T |
C |
19: 9,017,881 (GRCm38) |
S5510P |
probably damaging |
Het |
| Aldh3b1 |
T |
G |
19: 3,921,187 (GRCm38) |
D159A |
probably damaging |
Het |
| Alx1 |
A |
G |
10: 103,025,361 (GRCm38) |
L102P |
probably damaging |
Het |
| Ankrd50 |
C |
T |
3: 38,456,776 (GRCm38) |
V481I |
probably benign |
Het |
| Aox4 |
G |
T |
1: 58,264,402 (GRCm38) |
G1200W |
probably damaging |
Het |
| Arhgap45 |
A |
C |
10: 80,020,690 (GRCm38) |
D24A |
probably benign |
Het |
| Arhgef16 |
A |
T |
4: 154,280,323 (GRCm38) |
|
probably null |
Het |
| Asic4 |
A |
T |
1: 75,469,232 (GRCm38) |
Y235F |
possibly damaging |
Het |
| Asph |
T |
C |
4: 9,453,335 (GRCm38) |
E646G |
probably damaging |
Het |
| Atg4d |
A |
G |
9: 21,272,639 (GRCm38) |
D350G |
probably damaging |
Het |
| Auts2 |
T |
C |
5: 131,443,574 (GRCm38) |
T347A |
probably damaging |
Het |
| Bsnd |
A |
T |
4: 106,488,030 (GRCm38) |
L73* |
probably null |
Het |
| Cachd1 |
A |
T |
4: 100,953,169 (GRCm38) |
S323C |
probably damaging |
Het |
| Cacna1e |
A |
G |
1: 154,436,449 (GRCm38) |
I1290T |
probably damaging |
Het |
| Cdh8 |
T |
A |
8: 99,098,870 (GRCm38) |
N498Y |
probably damaging |
Het |
| Cdkn3 |
A |
G |
14: 46,769,834 (GRCm38) |
|
probably null |
Het |
| Celf2 |
A |
T |
2: 6,615,753 (GRCm38) |
M40K |
probably damaging |
Het |
| Cfap57 |
A |
C |
4: 118,615,010 (GRCm38) |
S57R |
probably damaging |
Het |
| Cfh |
A |
G |
1: 140,136,141 (GRCm38) |
|
probably null |
Het |
| Chdh |
A |
G |
14: 30,032,788 (GRCm38) |
S252G |
probably benign |
Het |
| Col8a1 |
T |
A |
16: 57,627,924 (GRCm38) |
I408F |
unknown |
Het |
| Corin |
C |
T |
5: 72,358,403 (GRCm38) |
C303Y |
probably damaging |
Het |
| Crlf2 |
C |
T |
5: 109,557,141 (GRCm38) |
C66Y |
possibly damaging |
Het |
| Csmd1 |
C |
T |
8: 16,233,998 (GRCm38) |
|
probably null |
Het |
| Cyp4f16 |
T |
C |
17: 32,545,044 (GRCm38) |
V270A |
probably damaging |
Het |
| Defa29 |
T |
A |
8: 21,326,012 (GRCm38) |
H113L |
possibly damaging |
Het |
| Dhx35 |
A |
T |
2: 158,842,307 (GRCm38) |
N501Y |
probably damaging |
Het |
| Dst |
A |
G |
1: 34,291,850 (GRCm38) |
R4690G |
probably damaging |
Het |
| Elac2 |
T |
A |
11: 64,994,263 (GRCm38) |
D439E |
probably benign |
Het |
| Ercc6 |
A |
G |
14: 32,576,803 (GRCm38) |
R1383G |
probably damaging |
Het |
| Fam69b |
A |
G |
2: 26,632,704 (GRCm38) |
E55G |
probably damaging |
Het |
| Fat3 |
T |
A |
9: 15,969,988 (GRCm38) |
Y3196F |
probably damaging |
Het |
| Fbxw13 |
A |
T |
9: 109,181,543 (GRCm38) |
D342E |
probably benign |
Het |
| Fmod |
A |
G |
1: 134,040,720 (GRCm38) |
N166S |
possibly damaging |
Het |
| Folh1 |
A |
G |
7: 86,762,967 (GRCm38) |
S199P |
possibly damaging |
Het |
| Fv1 |
A |
G |
4: 147,869,778 (GRCm38) |
N267S |
possibly damaging |
Het |
| Fyn |
T |
C |
10: 39,526,832 (GRCm38) |
V200A |
possibly damaging |
Het |
| Ggnbp2 |
T |
C |
11: 84,862,296 (GRCm38) |
N39S |
probably benign |
Het |
| Gm10509 |
A |
T |
17: 21,690,924 (GRCm38) |
I53F |
possibly damaging |
Het |
| Gpr139 |
A |
T |
7: 119,144,879 (GRCm38) |
I161N |
possibly damaging |
Het |
| Grhl2 |
C |
T |
15: 37,358,407 (GRCm38) |
T148I |
probably damaging |
Het |
| Hmcn1 |
C |
A |
1: 150,604,882 (GRCm38) |
M4514I |
probably benign |
Het |
| Itgav |
A |
G |
2: 83,795,486 (GRCm38) |
Y792C |
possibly damaging |
Het |
| Itgb2l |
T |
C |
16: 96,426,935 (GRCm38) |
Q456R |
probably benign |
Het |
| Jph4 |
G |
A |
14: 55,108,361 (GRCm38) |
A613V |
probably benign |
Het |
| Kcna2 |
A |
G |
3: 107,105,401 (GRCm38) |
T433A |
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,492,395 (GRCm38) |
K97R |
probably benign |
Het |
| Krba1 |
C |
A |
6: 48,415,765 (GRCm38) |
A871E |
probably benign |
Het |
| Loxhd1 |
T |
C |
18: 77,340,137 (GRCm38) |
F468L |
probably benign |
Het |
| Lpin1 |
A |
G |
12: 16,546,727 (GRCm38) |
V713A |
probably damaging |
Het |
| Ltbp2 |
T |
A |
12: 84,785,863 (GRCm38) |
I67F |
probably damaging |
Het |
| Mdc1 |
G |
A |
17: 35,844,538 (GRCm38) |
R35H |
probably benign |
Het |
| Mdc1 |
A |
G |
17: 35,850,811 (GRCm38) |
D872G |
probably benign |
Het |
| Mgam |
C |
T |
6: 40,764,185 (GRCm38) |
Q959* |
probably null |
Het |
| Mttp |
T |
A |
3: 138,116,027 (GRCm38) |
T260S |
probably benign |
Het |
| Naalad2 |
A |
T |
9: 18,376,535 (GRCm38) |
D266E |
probably benign |
Het |
| Nans |
T |
A |
4: 46,500,162 (GRCm38) |
L182H |
probably damaging |
Het |
| Nbas |
T |
A |
12: 13,566,144 (GRCm38) |
C2228S |
probably benign |
Het |
| Nfix |
A |
T |
8: 84,721,677 (GRCm38) |
V407E |
probably damaging |
Het |
| Nktr |
T |
A |
9: 121,750,240 (GRCm38) |
|
probably benign |
Het |
| Nlrp10 |
G |
A |
7: 108,925,395 (GRCm38) |
R293* |
probably null |
Het |
| Nrxn3 |
T |
C |
12: 88,795,342 (GRCm38) |
F53S |
probably damaging |
Het |
| Olfr1126 |
T |
C |
2: 87,457,383 (GRCm38) |
S73P |
probably damaging |
Het |
| Olfr212 |
A |
G |
6: 116,515,989 (GRCm38) |
T71A |
probably benign |
Het |
| Olfr380 |
A |
T |
11: 73,453,994 (GRCm38) |
F73I |
probably damaging |
Het |
| Olfr402 |
T |
C |
11: 74,155,885 (GRCm38) |
C244R |
probably damaging |
Het |
| Olfr452 |
T |
C |
6: 42,790,477 (GRCm38) |
I146T |
probably benign |
Het |
| Olfr493 |
A |
G |
7: 108,346,807 (GRCm38) |
L58P |
probably damaging |
Het |
| Olfr749 |
G |
A |
14: 50,736,778 (GRCm38) |
P128L |
probably damaging |
Het |
| Olfr994 |
T |
A |
2: 85,430,260 (GRCm38) |
N190Y |
probably damaging |
Het |
| Oxld1 |
A |
G |
11: 120,456,906 (GRCm38) |
V155A |
probably damaging |
Het |
| Pamr1 |
T |
A |
2: 102,642,300 (GRCm38) |
F648Y |
probably damaging |
Het |
| Parg |
T |
C |
14: 32,210,540 (GRCm38) |
W446R |
probably damaging |
Het |
| Phf3 |
A |
T |
1: 30,804,345 (GRCm38) |
H1844Q |
probably damaging |
Het |
| Phf7 |
T |
C |
14: 31,240,324 (GRCm38) |
I175V |
possibly damaging |
Het |
| Pibf1 |
G |
A |
14: 99,187,809 (GRCm38) |
|
probably null |
Het |
| Plcxd1 |
A |
G |
5: 110,103,442 (GRCm38) |
I295V |
probably benign |
Het |
| Pole2 |
A |
C |
12: 69,209,990 (GRCm38) |
Y254D |
probably damaging |
Het |
| Ppm1e |
T |
A |
11: 87,244,370 (GRCm38) |
I225F |
probably benign |
Het |
| Rem1 |
G |
A |
2: 152,634,535 (GRCm38) |
V238M |
probably damaging |
Het |
| Rnase2b |
T |
G |
14: 51,162,900 (GRCm38) |
V146G |
probably damaging |
Het |
| Rnf169 |
G |
A |
7: 99,926,254 (GRCm38) |
T378I |
probably damaging |
Het |
| Rpf2 |
A |
G |
10: 40,236,201 (GRCm38) |
F80L |
probably benign |
Het |
| Sec11c |
T |
A |
18: 65,814,874 (GRCm38) |
D128E |
probably damaging |
Het |
| Sept12 |
A |
G |
16: 4,988,553 (GRCm38) |
V248A |
probably damaging |
Het |
| Serinc1 |
T |
C |
10: 57,525,451 (GRCm38) |
N82S |
probably benign |
Het |
| Serpina9 |
A |
C |
12: 104,001,249 (GRCm38) |
W296G |
probably damaging |
Het |
| Sgo2b |
A |
C |
8: 63,931,469 (GRCm38) |
D164E |
probably damaging |
Het |
| Slc15a3 |
A |
G |
19: 10,848,613 (GRCm38) |
N223D |
probably damaging |
Het |
| Slc44a3 |
A |
G |
3: 121,532,166 (GRCm38) |
Y12H |
probably benign |
Het |
| Slco3a1 |
A |
G |
7: 74,504,611 (GRCm38) |
F42S |
probably damaging |
Het |
| Snrnp40 |
C |
G |
4: 130,378,043 (GRCm38) |
|
probably null |
Het |
| Snx7 |
A |
T |
3: 117,829,668 (GRCm38) |
|
probably null |
Het |
| Sorl1 |
A |
T |
9: 42,081,950 (GRCm38) |
D259E |
probably damaging |
Het |
| Stpg2 |
G |
A |
3: 139,522,981 (GRCm38) |
|
probably null |
Het |
| Strn |
T |
A |
17: 78,684,395 (GRCm38) |
Y165F |
probably damaging |
Het |
| Sval2 |
T |
A |
6: 41,864,320 (GRCm38) |
*106R |
probably null |
Het |
| Tcaf3 |
A |
G |
6: 42,596,688 (GRCm38) |
S197P |
possibly damaging |
Het |
| Tespa1 |
C |
A |
10: 130,354,723 (GRCm38) |
T73N |
probably benign |
Het |
| Tex10 |
C |
T |
4: 48,456,800 (GRCm38) |
R637Q |
probably benign |
Het |
| Thoc5 |
C |
A |
11: 4,915,561 (GRCm38) |
T380K |
probably benign |
Het |
| Tmprss7 |
T |
A |
16: 45,656,548 (GRCm38) |
R784* |
probably null |
Het |
| Trank1 |
A |
T |
9: 111,390,709 (GRCm38) |
L2171F |
probably benign |
Het |
| Trpm2 |
T |
G |
10: 77,945,876 (GRCm38) |
K303T |
probably benign |
Het |
| Tsta3 |
A |
T |
15: 75,925,649 (GRCm38) |
D278E |
possibly damaging |
Het |
| Unc80 |
G |
A |
1: 66,510,625 (GRCm38) |
V681M |
probably damaging |
Het |
| Usp40 |
A |
G |
1: 87,946,646 (GRCm38) |
F1131L |
probably benign |
Het |
| Vmn1r215 |
A |
T |
13: 23,076,503 (GRCm38) |
I238F |
possibly damaging |
Het |
| Vwa3a |
A |
T |
7: 120,795,627 (GRCm38) |
Y890F |
probably damaging |
Het |
| Zdhhc18 |
A |
G |
4: 133,613,860 (GRCm38) |
L234P |
probably damaging |
Het |
| Zfp109 |
A |
G |
7: 24,228,251 (GRCm38) |
S578P |
probably damaging |
Het |
| Zfp704 |
T |
C |
3: 9,609,358 (GRCm38) |
D121G |
unknown |
Het |
| Zgrf1 |
G |
T |
3: 127,563,137 (GRCm38) |
V671L |
probably benign |
Het |
| Zkscan8 |
A |
T |
13: 21,520,757 (GRCm38) |
C265* |
probably null |
Het |
| Zscan26 |
T |
C |
13: 21,445,140 (GRCm38) |
I398V |
possibly damaging |
Het |
|
| Other mutations in Igsf10 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00773:Igsf10
|
APN |
3 |
59,331,539 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL00790:Igsf10
|
APN |
3 |
59,319,517 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00916:Igsf10
|
APN |
3 |
59,331,127 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL00928:Igsf10
|
APN |
3 |
59,330,597 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01066:Igsf10
|
APN |
3 |
59,327,782 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL01107:Igsf10
|
APN |
3 |
59,331,524 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01420:Igsf10
|
APN |
3 |
59,319,650 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL01533:Igsf10
|
APN |
3 |
59,319,230 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01537:Igsf10
|
APN |
3 |
59,330,031 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01676:Igsf10
|
APN |
3 |
59,329,335 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01676:Igsf10
|
APN |
3 |
59,326,011 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL01960:Igsf10
|
APN |
3 |
59,318,737 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL02123:Igsf10
|
APN |
3 |
59,318,660 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02198:Igsf10
|
APN |
3 |
59,325,978 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02268:Igsf10
|
APN |
3 |
59,331,152 (GRCm38) |
nonsense |
probably null |
|
|
IGL02313:Igsf10
|
APN |
3 |
59,330,690 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02368:Igsf10
|
APN |
3 |
59,328,231 (GRCm38) |
missense |
probably benign |
|
|
IGL02494:Igsf10
|
APN |
3 |
59,328,006 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL02549:Igsf10
|
APN |
3 |
59,329,241 (GRCm38) |
missense |
probably benign |
0.03 |
|
IGL02616:Igsf10
|
APN |
3 |
59,318,606 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL02957:Igsf10
|
APN |
3 |
59,330,864 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03067:Igsf10
|
APN |
3 |
59,318,918 (GRCm38) |
missense |
probably benign |
0.25 |
|
IGL03104:Igsf10
|
APN |
3 |
59,319,484 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03124:Igsf10
|
APN |
3 |
59,319,665 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03212:Igsf10
|
APN |
3 |
59,328,165 (GRCm38) |
missense |
probably benign |
0.09 |
|
IGL03347:Igsf10
|
APN |
3 |
59,331,900 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL03357:Igsf10
|
APN |
3 |
59,336,211 (GRCm38) |
missense |
probably benign |
0.35 |
|
F6893:Igsf10
|
UTSW |
3 |
59,331,060 (GRCm38) |
missense |
probably damaging |
1.00 |
|
FR4449:Igsf10
|
UTSW |
3 |
59,319,110 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Igsf10
|
UTSW |
3 |
59,328,158 (GRCm38) |
missense |
probably benign |
0.06 |
|
PIT4402001:Igsf10
|
UTSW |
3 |
59,325,579 (GRCm38) |
missense |
probably benign |
0.00 |
|
PIT4810001:Igsf10
|
UTSW |
3 |
59,318,482 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0068:Igsf10
|
UTSW |
3 |
59,330,624 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0095:Igsf10
|
UTSW |
3 |
59,331,196 (GRCm38) |
nonsense |
probably null |
|
|
R0095:Igsf10
|
UTSW |
3 |
59,331,196 (GRCm38) |
nonsense |
probably null |
|
|
R0112:Igsf10
|
UTSW |
3 |
59,326,008 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0141:Igsf10
|
UTSW |
3 |
59,330,832 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0538:Igsf10
|
UTSW |
3 |
59,320,106 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0551:Igsf10
|
UTSW |
3 |
59,328,668 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0556:Igsf10
|
UTSW |
3 |
59,328,875 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0582:Igsf10
|
UTSW |
3 |
59,319,767 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0630:Igsf10
|
UTSW |
3 |
59,326,062 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0675:Igsf10
|
UTSW |
3 |
59,328,594 (GRCm38) |
missense |
probably benign |
0.14 |
|
R0948:Igsf10
|
UTSW |
3 |
59,331,104 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1252:Igsf10
|
UTSW |
3 |
59,331,848 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1412:Igsf10
|
UTSW |
3 |
59,327,775 (GRCm38) |
splice site |
probably benign |
|
|
R1473:Igsf10
|
UTSW |
3 |
59,318,767 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1585:Igsf10
|
UTSW |
3 |
59,330,417 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1650:Igsf10
|
UTSW |
3 |
59,326,162 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1660:Igsf10
|
UTSW |
3 |
59,331,285 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1671:Igsf10
|
UTSW |
3 |
59,328,500 (GRCm38) |
nonsense |
probably null |
|
|
R1748:Igsf10
|
UTSW |
3 |
59,319,093 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1758:Igsf10
|
UTSW |
3 |
59,329,196 (GRCm38) |
missense |
probably benign |
0.09 |
|
R1856:Igsf10
|
UTSW |
3 |
59,331,272 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R2148:Igsf10
|
UTSW |
3 |
59,336,577 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R2155:Igsf10
|
UTSW |
3 |
59,331,680 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2509:Igsf10
|
UTSW |
3 |
59,331,866 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2511:Igsf10
|
UTSW |
3 |
59,331,866 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2680:Igsf10
|
UTSW |
3 |
59,325,454 (GRCm38) |
missense |
probably benign |
0.14 |
|
R2913:Igsf10
|
UTSW |
3 |
59,331,736 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R2927:Igsf10
|
UTSW |
3 |
59,329,427 (GRCm38) |
missense |
probably benign |
|
|
R3547:Igsf10
|
UTSW |
3 |
59,336,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3547:Igsf10
|
UTSW |
3 |
59,330,541 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3548:Igsf10
|
UTSW |
3 |
59,336,514 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3620:Igsf10
|
UTSW |
3 |
59,336,331 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3732:Igsf10
|
UTSW |
3 |
59,325,714 (GRCm38) |
missense |
probably benign |
0.29 |
|
R3743:Igsf10
|
UTSW |
3 |
59,326,125 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R3973:Igsf10
|
UTSW |
3 |
59,331,924 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4005:Igsf10
|
UTSW |
3 |
59,328,560 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4184:Igsf10
|
UTSW |
3 |
59,319,731 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4302:Igsf10
|
UTSW |
3 |
59,318,750 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4404:Igsf10
|
UTSW |
3 |
59,329,551 (GRCm38) |
missense |
probably benign |
0.04 |
|
R4575:Igsf10
|
UTSW |
3 |
59,330,100 (GRCm38) |
missense |
probably benign |
|
|
R4676:Igsf10
|
UTSW |
3 |
59,325,949 (GRCm38) |
missense |
probably benign |
0.23 |
|
R4700:Igsf10
|
UTSW |
3 |
59,320,330 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4765:Igsf10
|
UTSW |
3 |
59,329,705 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4986:Igsf10
|
UTSW |
3 |
59,328,606 (GRCm38) |
missense |
probably benign |
0.24 |
|
R5012:Igsf10
|
UTSW |
3 |
59,318,722 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5070:Igsf10
|
UTSW |
3 |
59,328,293 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5083:Igsf10
|
UTSW |
3 |
59,326,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5336:Igsf10
|
UTSW |
3 |
59,320,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5462:Igsf10
|
UTSW |
3 |
59,325,754 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5648:Igsf10
|
UTSW |
3 |
59,328,153 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5810:Igsf10
|
UTSW |
3 |
59,319,071 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5871:Igsf10
|
UTSW |
3 |
59,330,411 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R5880:Igsf10
|
UTSW |
3 |
59,330,831 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5935:Igsf10
|
UTSW |
3 |
59,328,157 (GRCm38) |
missense |
probably benign |
0.12 |
|
R5979:Igsf10
|
UTSW |
3 |
59,336,473 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6145:Igsf10
|
UTSW |
3 |
59,331,656 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R6222:Igsf10
|
UTSW |
3 |
59,318,915 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R6224:Igsf10
|
UTSW |
3 |
59,325,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6264:Igsf10
|
UTSW |
3 |
59,328,507 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R6283:Igsf10
|
UTSW |
3 |
59,319,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6336:Igsf10
|
UTSW |
3 |
59,330,339 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6490:Igsf10
|
UTSW |
3 |
59,329,571 (GRCm38) |
missense |
probably benign |
0.06 |
|
R6785:Igsf10
|
UTSW |
3 |
59,319,244 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6873:Igsf10
|
UTSW |
3 |
59,328,444 (GRCm38) |
missense |
probably benign |
|
|
R6889:Igsf10
|
UTSW |
3 |
59,331,933 (GRCm38) |
missense |
probably benign |
|
|
R7024:Igsf10
|
UTSW |
3 |
59,331,701 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7056:Igsf10
|
UTSW |
3 |
59,331,080 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7128:Igsf10
|
UTSW |
3 |
59,328,905 (GRCm38) |
missense |
probably benign |
|
|
R7251:Igsf10
|
UTSW |
3 |
59,319,454 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7313:Igsf10
|
UTSW |
3 |
59,329,416 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7340:Igsf10
|
UTSW |
3 |
59,325,768 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7447:Igsf10
|
UTSW |
3 |
59,331,801 (GRCm38) |
missense |
probably benign |
0.39 |
|
R7506:Igsf10
|
UTSW |
3 |
59,319,354 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7678:Igsf10
|
UTSW |
3 |
59,319,340 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7695:Igsf10
|
UTSW |
3 |
59,326,191 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7709:Igsf10
|
UTSW |
3 |
59,331,543 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7749:Igsf10
|
UTSW |
3 |
59,329,128 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
R7808:Igsf10
|
UTSW |
3 |
59,328,068 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7850:Igsf10
|
UTSW |
3 |
59,319,632 (GRCm38) |
missense |
probably benign |
0.33 |
|
R7879:Igsf10
|
UTSW |
3 |
59,330,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7886:Igsf10
|
UTSW |
3 |
59,328,327 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7891:Igsf10
|
UTSW |
3 |
59,328,411 (GRCm38) |
nonsense |
probably null |
|
|
R7946:Igsf10
|
UTSW |
3 |
59,319,704 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R7948:Igsf10
|
UTSW |
3 |
59,331,858 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8004:Igsf10
|
UTSW |
3 |
59,329,709 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8096:Igsf10
|
UTSW |
3 |
59,328,959 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8141:Igsf10
|
UTSW |
3 |
59,330,528 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8183:Igsf10
|
UTSW |
3 |
59,330,615 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8203:Igsf10
|
UTSW |
3 |
59,328,833 (GRCm38) |
missense |
probably benign |
0.11 |
|
R8325:Igsf10
|
UTSW |
3 |
59,318,533 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R8350:Igsf10
|
UTSW |
3 |
59,331,528 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8387:Igsf10
|
UTSW |
3 |
59,329,143 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8488:Igsf10
|
UTSW |
3 |
59,320,010 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8697:Igsf10
|
UTSW |
3 |
59,318,887 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8786:Igsf10
|
UTSW |
3 |
59,330,642 (GRCm38) |
missense |
probably benign |
0.25 |
|
R8804:Igsf10
|
UTSW |
3 |
59,336,455 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8886:Igsf10
|
UTSW |
3 |
59,329,989 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8902:Igsf10
|
UTSW |
3 |
59,336,212 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8906:Igsf10
|
UTSW |
3 |
59,326,318 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8917:Igsf10
|
UTSW |
3 |
59,319,467 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R9051:Igsf10
|
UTSW |
3 |
59,329,247 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9178:Igsf10
|
UTSW |
3 |
59,326,059 (GRCm38) |
missense |
possibly damaging |
0.69 |
|
R9228:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9230:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9231:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9232:Igsf10
|
UTSW |
3 |
59,336,422 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9417:Igsf10
|
UTSW |
3 |
59,329,105 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R9609:Igsf10
|
UTSW |
3 |
59,319,448 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9631:Igsf10
|
UTSW |
3 |
59,330,483 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9689:Igsf10
|
UTSW |
3 |
59,326,203 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9762:Igsf10
|
UTSW |
3 |
59,329,685 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9770:Igsf10
|
UTSW |
3 |
59,319,778 (GRCm38) |
missense |
probably benign |
0.07 |
|
R9798:Igsf10
|
UTSW |
3 |
59,331,705 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Igsf10
|
UTSW |
3 |
59,329,938 (GRCm38) |
missense |
possibly damaging |
0.59 |
|
Z1177:Igsf10
|
UTSW |
3 |
59,329,605 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CATGCTTGCTTCAGTGGGAG -3'
(R):5'- TCCAAGCGCCCTTCAGATTC -3'
Sequencing Primer
(F):5'- GTGGGTACTTTCACTTCTGAAATAG -3'
(R):5'- TTCAGATTCCCACACCACTG -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation