Incidental Mutation 'R1869:Pcdhga1'
| ID |
210600 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdhga1
|
| Ensembl Gene |
ENSMUSG00000103144 |
| Gene Name |
protocadherin gamma subfamily A, 1 |
| Synonyms |
|
| MMRRC Submission |
039891-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1869 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
37794846-37974926 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 37973143 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 907
(N907K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000111325
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000003599]
[ENSMUST00000025337]
[ENSMUST00000044851]
[ENSMUST00000055935]
[ENSMUST00000061279]
[ENSMUST00000066140]
[ENSMUST00000066149]
[ENSMUST00000076807]
[ENSMUST00000192511]
[ENSMUST00000115661]
[ENSMUST00000192535]
[ENSMUST00000091935]
[ENSMUST00000073447]
[ENSMUST00000115629]
[ENSMUST00000115631]
[ENSMUST00000115634]
[ENSMUST00000192103]
[ENSMUST00000080033]
[ENSMUST00000195112]
[ENSMUST00000195823]
[ENSMUST00000194190]
[ENSMUST00000193404]
[ENSMUST00000192931]
[ENSMUST00000193869]
[ENSMUST00000193414]
[ENSMUST00000195363]
[ENSMUST00000194928]
[ENSMUST00000194418]
[ENSMUST00000195239]
[ENSMUST00000208907]
[ENSMUST00000195764]
[ENSMUST00000193890]
[ENSMUST00000193941]
|
| AlphaFold |
Q91XZ0 |
| PDB Structure |
Structure of EC1 domain of CNR [SOLUTION NMR]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000003599
AA Change: N918K
PolyPhen 2
Score 0.091 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000003599
Gene: ENSMUSG00000103088
AA Change: N918K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
131 |
8.06e-6 |
SMART |
|
CA
|
155 |
240 |
2.29e-19 |
SMART |
|
CA
|
264 |
345 |
3.36e-26 |
SMART |
|
CA
|
369 |
450 |
4.94e-24 |
SMART |
|
CA
|
474 |
560 |
7.6e-25 |
SMART |
|
CA
|
591 |
672 |
9.18e-10 |
SMART |
|
Pfam:Cadherin_C_2
|
687 |
768 |
3.5e-20 |
PFAM |
|
Pfam:Cadherin_tail
|
807 |
930 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000025337
|
| SMART Domains |
Protein: ENSMUSP00000025337
Gene: ENSMUSG00000024456
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
13 |
N/A |
INTRINSIC |
|
Drf_GBD
|
84 |
268 |
1.07e-57 |
SMART |
|
Drf_FH3
|
274 |
466 |
2.06e-68 |
SMART |
|
coiled coil region
|
471 |
571 |
N/A |
INTRINSIC |
|
Pfam:Drf_FH1
|
609 |
756 |
6.1e-43 |
PFAM |
|
FH2
|
761 |
1206 |
2.46e-182 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000044851
AA Change: N920K
|
| SMART Domains |
Protein: ENSMUSP00000036359
Gene: ENSMUSG00000102428
AA Change: N920K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
12 |
23 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
3.28e-1 |
SMART |
|
CA
|
155 |
240 |
1.8e-17 |
SMART |
|
CA
|
264 |
345 |
9.22e-24 |
SMART |
|
CA
|
369 |
450 |
1.28e-22 |
SMART |
|
CA
|
474 |
560 |
1.09e-25 |
SMART |
|
CA
|
591 |
669 |
9.24e-15 |
SMART |
|
Pfam:Cadherin_C_2
|
688 |
772 |
3.6e-25 |
PFAM |
|
Pfam:Cadherin_tail
|
809 |
932 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000055935
AA Change: N932K
|
| SMART Domains |
Protein: ENSMUSP00000060949
Gene: ENSMUSG00000102543
AA Change: N932K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
54 |
131 |
3.02e-2 |
SMART |
|
CA
|
155 |
240 |
6.84e-18 |
SMART |
|
CA
|
264 |
348 |
7.91e-23 |
SMART |
|
CA
|
372 |
452 |
4.4e-21 |
SMART |
|
CA
|
476 |
562 |
3.31e-25 |
SMART |
|
CA
|
592 |
674 |
5.69e-15 |
SMART |
|
Pfam:Cadherin_C_2
|
689 |
791 |
1.1e-18 |
PFAM |
|
low complexity region
|
808 |
819 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
821 |
944 |
8.3e-38 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000061279
AA Change: N921K
|
| SMART Domains |
Protein: ENSMUSP00000058362
Gene: ENSMUSG00000102742
AA Change: N921K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
3.23e-2 |
SMART |
|
CA
|
155 |
240 |
2.22e-17 |
SMART |
|
CA
|
264 |
345 |
3.36e-26 |
SMART |
|
CA
|
369 |
450 |
7.09e-25 |
SMART |
|
CA
|
474 |
560 |
3.55e-25 |
SMART |
|
CA
|
591 |
669 |
2.53e-12 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
933 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066140
AA Change: N929K
PolyPhen 2
Score 0.961 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000068846
Gene: ENSMUSG00000023036
AA Change: N929K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
52 |
134 |
4.39e-1 |
SMART |
|
CA
|
158 |
243 |
1.25e-20 |
SMART |
|
CA
|
267 |
351 |
5.09e-26 |
SMART |
|
CA
|
375 |
456 |
1.26e-21 |
SMART |
|
CA
|
480 |
566 |
6.56e-29 |
SMART |
|
CA
|
596 |
674 |
6.95e-10 |
SMART |
|
transmembrane domain
|
693 |
715 |
N/A |
INTRINSIC |
|
low complexity region
|
922 |
941 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066149
AA Change: N920K
|
| SMART Domains |
Protein: ENSMUSP00000067728
Gene: ENSMUSG00000103897
AA Change: N920K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
CA
|
31 |
131 |
4.84e-2 |
SMART |
|
CA
|
155 |
240 |
1.48e-22 |
SMART |
|
CA
|
264 |
345 |
1.14e-23 |
SMART |
|
CA
|
369 |
450 |
9.44e-21 |
SMART |
|
CA
|
474 |
560 |
1.03e-26 |
SMART |
|
CA
|
591 |
669 |
3.64e-13 |
SMART |
|
Pfam:Cadherin_C_2
|
688 |
772 |
3e-25 |
PFAM |
|
Pfam:Cadherin_tail
|
809 |
932 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000076807
AA Change: N922K
|
| SMART Domains |
Protein: ENSMUSP00000076085
Gene: ENSMUSG00000102918
AA Change: N922K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
26 |
N/A |
INTRINSIC |
|
CA
|
51 |
133 |
8.56e-3 |
SMART |
|
CA
|
157 |
242 |
1.78e-16 |
SMART |
|
CA
|
266 |
350 |
2.18e-25 |
SMART |
|
CA
|
374 |
455 |
7.09e-25 |
SMART |
|
CA
|
479 |
565 |
1.87e-24 |
SMART |
|
CA
|
593 |
674 |
1.79e-12 |
SMART |
|
Pfam:Cadherin_C_2
|
689 |
774 |
3.9e-14 |
PFAM |
|
Pfam:Cadherin_tail
|
811 |
934 |
8.2e-38 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192511
AA Change: N923K
|
| SMART Domains |
Protein: ENSMUSP00000141704
Gene: ENSMUSG00000103472
AA Change: N923K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
133 |
1.57e-2 |
SMART |
|
CA
|
157 |
242 |
3.24e-19 |
SMART |
|
CA
|
266 |
347 |
3.21e-23 |
SMART |
|
CA
|
371 |
452 |
9.08e-23 |
SMART |
|
CA
|
476 |
562 |
1.32e-24 |
SMART |
|
CA
|
593 |
671 |
3.5e-15 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
low complexity region
|
916 |
935 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000115661
AA Change: N907K
PolyPhen 2
Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458
AA Change: N907K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
674 |
4.12e-12 |
SMART |
|
low complexity region
|
706 |
721 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
796 |
930 |
3.9e-58 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192861
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192535
AA Change: N914K
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000142010
Gene: ENSMUSG00000103749
AA Change: N914K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
25 |
N/A |
INTRINSIC |
|
CA
|
56 |
131 |
8e-3 |
SMART |
|
CA
|
155 |
240 |
2.49e-20 |
SMART |
|
CA
|
264 |
341 |
4.97e-29 |
SMART |
|
CA
|
365 |
446 |
1.09e-25 |
SMART |
|
CA
|
470 |
556 |
1.75e-24 |
SMART |
|
CA
|
587 |
668 |
9.18e-10 |
SMART |
|
transmembrane domain
|
687 |
709 |
N/A |
INTRINSIC |
|
low complexity region
|
907 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192875
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000091935
AA Change: N920K
|
| SMART Domains |
Protein: ENSMUSP00000089555
Gene: ENSMUSG00000102440
AA Change: N920K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
CA
|
32 |
132 |
8.37e-3 |
SMART |
|
CA
|
156 |
241 |
5.51e-22 |
SMART |
|
CA
|
265 |
346 |
8.27e-26 |
SMART |
|
CA
|
370 |
451 |
1.4e-23 |
SMART |
|
CA
|
475 |
561 |
2.97e-27 |
SMART |
|
CA
|
592 |
670 |
1.18e-12 |
SMART |
|
Pfam:Cadherin_C_2
|
688 |
772 |
3.9e-24 |
PFAM |
|
Pfam:Cadherin_tail
|
809 |
932 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000073447
AA Change: N916K
|
| SMART Domains |
Protein: ENSMUSP00000073150
Gene: ENSMUSG00000104346
AA Change: N916K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
CA
|
42 |
128 |
2.15e-2 |
SMART |
|
CA
|
152 |
237 |
4.8e-13 |
SMART |
|
CA
|
261 |
342 |
9.36e-25 |
SMART |
|
CA
|
366 |
447 |
6.62e-25 |
SMART |
|
CA
|
471 |
557 |
6.72e-26 |
SMART |
|
CA
|
588 |
666 |
2.15e-15 |
SMART |
|
Pfam:Cadherin_C_2
|
685 |
768 |
4.8e-24 |
PFAM |
|
Pfam:Cadherin_tail
|
805 |
928 |
8.1e-38 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192109
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115629
|
| SMART Domains |
Protein: ENSMUSP00000111292
Gene: ENSMUSG00000024456
| Domain | Start | End | E-Value | Type |
|---|
|
Drf_GBD
|
40 |
224 |
1.07e-57 |
SMART |
|
Drf_FH3
|
230 |
422 |
2.06e-68 |
SMART |
|
coiled coil region
|
427 |
527 |
N/A |
INTRINSIC |
|
Pfam:Drf_FH1
|
554 |
712 |
7.6e-52 |
PFAM |
|
FH2
|
717 |
1162 |
3.73e-182 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115631
|
| SMART Domains |
Protein: ENSMUSP00000111294
Gene: ENSMUSG00000024456
| Domain | Start | End | E-Value | Type |
|---|
|
Drf_GBD
|
40 |
224 |
1.07e-57 |
SMART |
|
Drf_FH3
|
230 |
422 |
2.06e-68 |
SMART |
|
coiled coil region
|
427 |
527 |
N/A |
INTRINSIC |
|
Pfam:Drf_FH1
|
554 |
712 |
1.1e-51 |
PFAM |
|
FH2
|
717 |
1162 |
2.46e-182 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115634
|
| SMART Domains |
Protein: ENSMUSP00000111297
Gene: ENSMUSG00000024456
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
13 |
N/A |
INTRINSIC |
|
Drf_GBD
|
75 |
259 |
1.07e-57 |
SMART |
|
Drf_FH3
|
265 |
457 |
2.06e-68 |
SMART |
|
coiled coil region
|
462 |
562 |
N/A |
INTRINSIC |
|
Pfam:Drf_FH1
|
589 |
747 |
9.4e-52 |
PFAM |
|
FH2
|
752 |
1197 |
2.46e-182 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192103
|
| SMART Domains |
Protein: ENSMUSP00000141611
Gene: ENSMUSG00000102918
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_2
|
31 |
78 |
2.3e-13 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080033
|
| SMART Domains |
Protein: ENSMUSP00000078942
Gene: ENSMUSG00000024456
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
13 |
N/A |
INTRINSIC |
|
Drf_GBD
|
75 |
259 |
1.07e-57 |
SMART |
|
Drf_FH3
|
265 |
457 |
2.06e-68 |
SMART |
|
coiled coil region
|
462 |
562 |
N/A |
INTRINSIC |
|
Pfam:Drf_FH1
|
589 |
747 |
7.9e-52 |
PFAM |
|
FH2
|
752 |
1197 |
3.73e-182 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194980
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195112
AA Change: N916K
|
| SMART Domains |
Protein: ENSMUSP00000141449
Gene: ENSMUSG00000102748
AA Change: N916K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
24 |
130 |
8.18e-3 |
SMART |
|
CA
|
154 |
239 |
1.39e-18 |
SMART |
|
CA
|
263 |
344 |
7.91e-23 |
SMART |
|
CA
|
368 |
449 |
2.27e-23 |
SMART |
|
CA
|
473 |
559 |
1.24e-24 |
SMART |
|
CA
|
590 |
671 |
1.3e-9 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
928 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195823
AA Change: N920K
PolyPhen 2
Score 0.032 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000141803
Gene: ENSMUSG00000103793
AA Change: N920K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
13 |
24 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
2.41e-2 |
SMART |
|
CA
|
155 |
240 |
5.77e-16 |
SMART |
|
CA
|
264 |
345 |
1.1e-21 |
SMART |
|
CA
|
369 |
450 |
2.75e-22 |
SMART |
|
low complexity region
|
453 |
462 |
N/A |
INTRINSIC |
|
CA
|
474 |
560 |
9.22e-24 |
SMART |
|
CA
|
591 |
669 |
2.4e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194190
AA Change: N919K
PolyPhen 2
Score 0.032 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000142062
Gene: ENSMUSG00000103144
AA Change: N919K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
31 |
131 |
3.16e-2 |
SMART |
|
CA
|
155 |
240 |
5.39e-16 |
SMART |
|
CA
|
264 |
345 |
6.72e-26 |
SMART |
|
CA
|
369 |
450 |
1.32e-24 |
SMART |
|
CA
|
474 |
560 |
4.17e-22 |
SMART |
|
CA
|
591 |
669 |
4.48e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000193404
AA Change: N918K
|
| SMART Domains |
Protein: ENSMUSP00000141359
Gene: ENSMUSG00000102222
AA Change: N918K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
43 |
129 |
2.76e-2 |
SMART |
|
CA
|
153 |
238 |
1.16e-20 |
SMART |
|
CA
|
262 |
343 |
1.25e-25 |
SMART |
|
CA
|
367 |
448 |
4.75e-26 |
SMART |
|
CA
|
472 |
558 |
3.69e-23 |
SMART |
|
CA
|
589 |
667 |
3.84e-12 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
930 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194068
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192984
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000192931
AA Change: N906K
|
| SMART Domains |
Protein: ENSMUSP00000141348
Gene: ENSMUSG00000103037
AA Change: N906K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
36 |
119 |
8e-3 |
SMART |
|
CA
|
143 |
228 |
1.34e-20 |
SMART |
|
CA
|
252 |
333 |
1.52e-24 |
SMART |
|
CA
|
357 |
438 |
9.22e-24 |
SMART |
|
CA
|
462 |
548 |
1.24e-24 |
SMART |
|
CA
|
579 |
660 |
1.3e-9 |
SMART |
|
transmembrane domain
|
679 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
899 |
918 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000193869
AA Change: N919K
|
| SMART Domains |
Protein: ENSMUSP00000141482
Gene: ENSMUSG00000103332
AA Change: N919K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
CA
|
45 |
131 |
1.64e-2 |
SMART |
|
CA
|
155 |
240 |
6.42e-23 |
SMART |
|
CA
|
264 |
345 |
1.76e-20 |
SMART |
|
CA
|
369 |
450 |
2.27e-23 |
SMART |
|
CA
|
474 |
560 |
1.5e-23 |
SMART |
|
CA
|
591 |
669 |
1.17e-16 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
912 |
931 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000193414
AA Change: N920K
|
| SMART Domains |
Protein: ENSMUSP00000141893
Gene: ENSMUSG00000103567
AA Change: N920K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
2.45e-1 |
SMART |
|
CA
|
155 |
240 |
1.05e-18 |
SMART |
|
CA
|
264 |
345 |
6.52e-24 |
SMART |
|
CA
|
369 |
450 |
5.99e-23 |
SMART |
|
CA
|
474 |
560 |
6.99e-24 |
SMART |
|
CA
|
591 |
669 |
5.31e-15 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
932 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195363
AA Change: N900K
|
| SMART Domains |
Protein: ENSMUSP00000142227
Gene: ENSMUSG00000103585
AA Change: N900K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
25 |
N/A |
INTRINSIC |
|
CA
|
56 |
131 |
1.47e-2 |
SMART |
|
CA
|
155 |
240 |
1.23e-19 |
SMART |
|
CA
|
264 |
343 |
5.54e-27 |
SMART |
|
CA
|
367 |
448 |
5.09e-26 |
SMART |
|
CA
|
472 |
558 |
1.98e-23 |
SMART |
|
CA
|
589 |
670 |
1.3e-9 |
SMART |
|
transmembrane domain
|
689 |
711 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
912 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000194928
AA Change: N917K
|
| SMART Domains |
Protein: ENSMUSP00000141997
Gene: ENSMUSG00000104063
AA Change: N917K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
47 |
131 |
2.48e-6 |
SMART |
|
CA
|
155 |
240 |
1.57e-17 |
SMART |
|
CA
|
264 |
343 |
1.29e-27 |
SMART |
|
CA
|
367 |
448 |
9.14e-28 |
SMART |
|
CA
|
472 |
558 |
1.24e-24 |
SMART |
|
CA
|
589 |
670 |
3.73e-10 |
SMART |
|
transmembrane domain
|
689 |
711 |
N/A |
INTRINSIC |
|
low complexity region
|
716 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
929 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000194418
AA Change: N918K
|
| SMART Domains |
Protein: ENSMUSP00000142140
Gene: ENSMUSG00000103677
AA Change: N918K
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
44 |
130 |
1.64e-2 |
SMART |
|
CA
|
154 |
239 |
3.93e-18 |
SMART |
|
CA
|
263 |
344 |
5.22e-23 |
SMART |
|
CA
|
368 |
449 |
5.02e-25 |
SMART |
|
CA
|
473 |
559 |
2.07e-26 |
SMART |
|
CA
|
590 |
668 |
6.84e-18 |
SMART |
|
transmembrane domain
|
690 |
712 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
930 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195239
AA Change: N119K
|
| SMART Domains |
Protein: ENSMUSP00000141244
Gene: ENSMUSG00000023036
AA Change: N119K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
112 |
131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000208907
AA Change: N919K
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195764
AA Change: N919K
|
| SMART Domains |
Protein: ENSMUSP00000142272
Gene: ENSMUSG00000103081
AA Change: N919K
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
29 |
N/A |
INTRINSIC |
|
CA
|
57 |
132 |
1.5e-4 |
SMART |
|
CA
|
156 |
241 |
1.2e-20 |
SMART |
|
CA
|
265 |
346 |
7.8e-29 |
SMART |
|
CA
|
370 |
451 |
1.7e-26 |
SMART |
|
CA
|
475 |
561 |
2.2e-26 |
SMART |
|
CA
|
592 |
673 |
6.4e-12 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
911 |
930 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193890
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193941
|
| Meta Mutation Damage Score |
0.0904 |
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null/reporter allele are viable and fertile. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 127 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921536K21Rik |
A |
G |
11: 3,840,067 (GRCm39) |
L110P |
probably damaging |
Het |
| 6030458C11Rik |
T |
C |
15: 12,817,993 (GRCm39) |
D168G |
probably damaging |
Het |
| Abca13 |
A |
T |
11: 9,242,134 (GRCm39) |
E1332D |
probably benign |
Het |
| Abhd11 |
A |
G |
5: 135,040,471 (GRCm39) |
Y168C |
probably damaging |
Het |
| Actr5 |
A |
C |
2: 158,480,643 (GRCm39) |
T554P |
probably damaging |
Het |
| Adam34l |
A |
T |
8: 44,078,132 (GRCm39) |
Y697* |
probably null |
Het |
| Adamts16 |
A |
G |
13: 70,883,866 (GRCm39) |
L1103P |
probably damaging |
Het |
| Adgrb3 |
A |
T |
1: 25,865,519 (GRCm39) |
I108K |
possibly damaging |
Het |
| Agbl4 |
T |
A |
4: 111,423,826 (GRCm39) |
M284K |
possibly damaging |
Het |
| Aoc3 |
T |
A |
11: 101,222,293 (GRCm39) |
Y176* |
probably null |
Het |
| Aox1 |
A |
G |
1: 58,115,262 (GRCm39) |
E749G |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,728,184 (GRCm39) |
Y399* |
probably null |
Het |
| Arhgef5 |
A |
T |
6: 43,265,616 (GRCm39) |
I1553F |
probably damaging |
Het |
| Bag6 |
T |
C |
17: 35,361,802 (GRCm39) |
V541A |
probably benign |
Het |
| Bdp1 |
A |
C |
13: 100,178,709 (GRCm39) |
V1879G |
probably damaging |
Het |
| Bod1l |
G |
A |
5: 41,991,018 (GRCm39) |
S179F |
possibly damaging |
Het |
| Bsnd |
C |
T |
4: 106,343,833 (GRCm39) |
V158I |
probably benign |
Het |
| Cachd1 |
C |
A |
4: 100,840,587 (GRCm39) |
H880N |
probably damaging |
Het |
| Ccdc27 |
T |
C |
4: 154,111,220 (GRCm39) |
|
probably null |
Het |
| Cd74 |
C |
T |
18: 60,943,484 (GRCm39) |
P190S |
probably benign |
Het |
| Cep68 |
A |
T |
11: 20,190,217 (GRCm39) |
L265Q |
probably damaging |
Het |
| Cfap70 |
G |
A |
14: 20,458,678 (GRCm39) |
Q772* |
probably null |
Het |
| CK137956 |
T |
A |
4: 127,864,327 (GRCm39) |
S101C |
possibly damaging |
Het |
| Clca3a2 |
G |
A |
3: 144,512,164 (GRCm39) |
T524M |
probably benign |
Het |
| Cxcr6 |
T |
C |
9: 123,639,022 (GRCm39) |
S15P |
probably benign |
Het |
| Cyfip2 |
T |
A |
11: 46,114,995 (GRCm39) |
Y904F |
probably benign |
Het |
| D130040H23Rik |
T |
A |
8: 69,755,354 (GRCm39) |
I253N |
probably benign |
Het |
| Ddx56 |
C |
T |
11: 6,213,993 (GRCm39) |
V389M |
possibly damaging |
Het |
| Dmp1 |
A |
T |
5: 104,359,942 (GRCm39) |
D206V |
probably damaging |
Het |
| Dnah17 |
A |
T |
11: 117,938,015 (GRCm39) |
C3350* |
probably null |
Het |
| Dst |
A |
T |
1: 34,291,913 (GRCm39) |
S877C |
probably damaging |
Het |
| Ermp1 |
A |
G |
19: 29,623,415 (GRCm39) |
S192P |
possibly damaging |
Het |
| F13b |
G |
A |
1: 139,438,672 (GRCm39) |
D359N |
probably benign |
Het |
| Fam171a1 |
A |
T |
2: 3,227,189 (GRCm39) |
Q769L |
possibly damaging |
Het |
| Fap |
T |
C |
2: 62,359,071 (GRCm39) |
R411G |
probably damaging |
Het |
| Fbn1 |
A |
G |
2: 125,193,947 (GRCm39) |
V1340A |
probably benign |
Het |
| Fbxw19 |
T |
C |
9: 109,311,100 (GRCm39) |
I370V |
probably benign |
Het |
| Foxi1 |
A |
T |
11: 34,157,937 (GRCm39) |
N29K |
possibly damaging |
Het |
| Frem2 |
T |
G |
3: 53,442,617 (GRCm39) |
D2640A |
probably benign |
Het |
| Fzd4 |
T |
C |
7: 89,056,454 (GRCm39) |
V167A |
probably benign |
Het |
| Galnt3 |
T |
C |
2: 65,928,123 (GRCm39) |
I258V |
possibly damaging |
Het |
| Galr2 |
T |
C |
11: 116,174,069 (GRCm39) |
V233A |
possibly damaging |
Het |
| Gldc |
G |
T |
19: 30,116,732 (GRCm39) |
Q407K |
probably benign |
Het |
| Gmcl1 |
T |
C |
6: 86,674,498 (GRCm39) |
D460G |
probably benign |
Het |
| Gpr89 |
A |
G |
3: 96,782,975 (GRCm39) |
I325T |
probably benign |
Het |
| Grap |
T |
A |
11: 61,555,015 (GRCm39) |
Y61N |
possibly damaging |
Het |
| Hbs1l |
G |
T |
10: 21,234,305 (GRCm39) |
|
probably null |
Het |
| Hexb |
T |
A |
13: 97,327,767 (GRCm39) |
E134D |
probably benign |
Het |
| Hydin |
T |
A |
8: 111,227,337 (GRCm39) |
V1507D |
possibly damaging |
Het |
| Igkv8-16 |
C |
A |
6: 70,363,971 (GRCm39) |
G17V |
probably benign |
Het |
| Kdm4a |
T |
A |
4: 117,996,068 (GRCm39) |
Q987L |
probably null |
Het |
| Krt76 |
A |
G |
15: 101,797,922 (GRCm39) |
|
probably null |
Het |
| Lap3 |
T |
C |
5: 45,660,729 (GRCm39) |
S238P |
probably benign |
Het |
| Letm2 |
T |
C |
8: 26,071,729 (GRCm39) |
D391G |
probably damaging |
Het |
| Lipn |
A |
G |
19: 34,058,139 (GRCm39) |
T287A |
possibly damaging |
Het |
| Macf1 |
T |
C |
4: 123,244,921 (GRCm39) |
S466G |
probably damaging |
Het |
| Map3k5 |
C |
A |
10: 20,007,855 (GRCm39) |
S1220* |
probably null |
Het |
| Map4 |
T |
A |
9: 109,897,996 (GRCm39) |
S754R |
possibly damaging |
Het |
| Map4 |
T |
C |
9: 109,864,032 (GRCm39) |
V419A |
probably benign |
Het |
| Mroh9 |
A |
G |
1: 162,854,082 (GRCm39) |
S773P |
probably damaging |
Het |
| Mtus1 |
A |
C |
8: 41,529,267 (GRCm39) |
|
probably null |
Het |
| Muc1 |
C |
T |
3: 89,139,117 (GRCm39) |
P533S |
probably damaging |
Het |
| Muc13 |
A |
T |
16: 33,624,970 (GRCm39) |
I282F |
probably damaging |
Het |
| Mucl3 |
A |
G |
17: 35,949,305 (GRCm39) |
L98P |
possibly damaging |
Het |
| Myh14 |
T |
A |
7: 44,261,067 (GRCm39) |
Q1816L |
possibly damaging |
Het |
| Nalcn |
A |
C |
14: 123,831,965 (GRCm39) |
V103G |
possibly damaging |
Het |
| Nlrp9c |
G |
A |
7: 26,084,245 (GRCm39) |
Q445* |
probably null |
Het |
| Olfml2b |
A |
G |
1: 170,496,812 (GRCm39) |
D481G |
probably damaging |
Het |
| Or13g1 |
T |
A |
7: 85,955,875 (GRCm39) |
I149F |
possibly damaging |
Het |
| Or2ag19 |
T |
G |
7: 106,444,301 (GRCm39) |
I161S |
probably benign |
Het |
| Or5g23 |
A |
G |
2: 85,438,844 (GRCm39) |
S137P |
probably benign |
Het |
| Or8b37 |
T |
A |
9: 37,959,498 (GRCm39) |
|
probably null |
Het |
| Or8k3b |
T |
A |
2: 86,520,735 (GRCm39) |
I195F |
probably damaging |
Het |
| Pcdhb2 |
A |
T |
18: 37,430,408 (GRCm39) |
|
probably null |
Het |
| Pcdhb22 |
A |
C |
18: 37,652,200 (GRCm39) |
T223P |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,215,740 (GRCm39) |
E2347G |
probably null |
Het |
| Phax |
T |
A |
18: 56,706,176 (GRCm39) |
V22D |
probably benign |
Het |
| Pik3ca |
T |
C |
3: 32,504,499 (GRCm39) |
F667S |
probably damaging |
Het |
| Pkd1 |
T |
C |
17: 24,813,905 (GRCm39) |
F4123S |
probably damaging |
Het |
| Pkhd1 |
A |
G |
1: 20,685,491 (GRCm39) |
|
probably null |
Het |
| Plcb1 |
G |
A |
2: 135,152,934 (GRCm39) |
R368K |
probably benign |
Het |
| Prrc2a |
G |
T |
17: 35,372,284 (GRCm39) |
R1739S |
possibly damaging |
Het |
| Psg23 |
A |
T |
7: 18,348,543 (GRCm39) |
M88K |
probably benign |
Het |
| Pstk |
T |
A |
7: 130,989,526 (GRCm39) |
Y354N |
probably damaging |
Het |
| Rab39 |
A |
G |
9: 53,617,231 (GRCm39) |
I62T |
possibly damaging |
Het |
| Ranbp2 |
A |
G |
10: 58,328,383 (GRCm39) |
I2800V |
probably damaging |
Het |
| Rasgrp1 |
T |
C |
2: 117,120,828 (GRCm39) |
Y431C |
probably damaging |
Het |
| Rest |
T |
A |
5: 77,416,209 (GRCm39) |
V141E |
possibly damaging |
Het |
| Rnf167 |
T |
A |
11: 70,540,965 (GRCm39) |
I197N |
possibly damaging |
Het |
| Rtn1 |
A |
G |
12: 72,354,942 (GRCm39) |
S335P |
probably damaging |
Het |
| Ryr2 |
G |
T |
13: 11,676,961 (GRCm39) |
R3297S |
probably damaging |
Het |
| S1pr3 |
A |
C |
13: 51,573,952 (GRCm39) |
K378Q |
probably benign |
Het |
| Scgb1b24 |
T |
C |
7: 33,443,469 (GRCm39) |
Y43H |
probably damaging |
Het |
| Sh3rf3 |
T |
A |
10: 58,919,335 (GRCm39) |
M484K |
probably damaging |
Het |
| Shank1 |
A |
T |
7: 43,991,539 (GRCm39) |
R69* |
probably null |
Het |
| Siglecf |
A |
G |
7: 43,004,967 (GRCm39) |
N399S |
probably benign |
Het |
| Slc1a7 |
A |
G |
4: 107,865,561 (GRCm39) |
T350A |
probably damaging |
Het |
| Slc25a54 |
T |
A |
3: 108,987,932 (GRCm39) |
Y24* |
probably null |
Het |
| Slk |
T |
C |
19: 47,613,891 (GRCm39) |
F916L |
probably damaging |
Het |
| Snap91 |
T |
A |
9: 86,672,194 (GRCm39) |
|
probably null |
Het |
| Snrpb2 |
A |
T |
2: 142,907,106 (GRCm39) |
R25S |
possibly damaging |
Het |
| Specc1l |
T |
C |
10: 75,097,659 (GRCm39) |
Y811H |
probably damaging |
Het |
| Sprr2h |
A |
G |
3: 92,293,925 (GRCm39) |
|
probably benign |
Het |
| Sult2a5 |
A |
T |
7: 13,358,045 (GRCm39) |
I26F |
probably benign |
Het |
| Syt13 |
C |
T |
2: 92,776,448 (GRCm39) |
T245I |
possibly damaging |
Het |
| Tecrl |
T |
A |
5: 83,502,706 (GRCm39) |
T33S |
probably benign |
Het |
| Telo2 |
T |
A |
17: 25,333,968 (GRCm39) |
D93V |
probably benign |
Het |
| Tet2 |
A |
T |
3: 133,187,202 (GRCm39) |
|
probably null |
Het |
| Tgm7 |
A |
T |
2: 120,931,570 (GRCm39) |
C198S |
probably damaging |
Het |
| Ticrr |
T |
C |
7: 79,328,883 (GRCm39) |
F674S |
probably damaging |
Het |
| Tmem129 |
C |
A |
5: 33,811,843 (GRCm39) |
C31F |
probably damaging |
Het |
| Tmem132a |
T |
A |
19: 10,836,052 (GRCm39) |
D826V |
possibly damaging |
Het |
| Tpd52 |
T |
C |
3: 9,018,862 (GRCm39) |
|
probably null |
Het |
| Trub2 |
A |
G |
2: 29,667,678 (GRCm39) |
S321P |
probably benign |
Het |
| Ttc29 |
A |
G |
8: 79,009,014 (GRCm39) |
T295A |
probably benign |
Het |
| Tubb1 |
G |
A |
2: 174,298,482 (GRCm39) |
S89N |
probably benign |
Het |
| Tut4 |
T |
A |
4: 108,386,497 (GRCm39) |
F1122L |
probably damaging |
Het |
| Ubap2 |
C |
A |
4: 41,233,617 (GRCm39) |
G91V |
probably damaging |
Het |
| Ugt2b35 |
A |
G |
5: 87,149,147 (GRCm39) |
N133D |
probably damaging |
Het |
| Usp34 |
A |
G |
11: 23,314,479 (GRCm39) |
H807R |
probably benign |
Het |
| Vmn1r220 |
A |
C |
13: 23,368,457 (GRCm39) |
C80G |
probably damaging |
Het |
| Vmn1r79 |
A |
G |
7: 11,910,574 (GRCm39) |
E152G |
probably benign |
Het |
| Vmn2r28 |
T |
C |
7: 5,489,345 (GRCm39) |
Y498C |
probably benign |
Het |
| Wif1 |
A |
G |
10: 120,920,824 (GRCm39) |
I215M |
probably benign |
Het |
| Wnk1 |
T |
C |
6: 119,928,050 (GRCm39) |
T1134A |
probably damaging |
Het |
| Zfp90 |
A |
G |
8: 107,145,755 (GRCm39) |
H29R |
probably benign |
Het |
| Zfp972 |
A |
G |
2: 177,563,480 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Pcdhga1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
BB009:Pcdhga1
|
UTSW |
18 |
37,796,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB019:Pcdhga1
|
UTSW |
18 |
37,796,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1074:Pcdhga1
|
UTSW |
18 |
37,958,140 (GRCm39) |
splice site |
probably benign |
|
|
R1871:Pcdhga1
|
UTSW |
18 |
37,973,143 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3723:Pcdhga1
|
UTSW |
18 |
37,796,045 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3732:Pcdhga1
|
UTSW |
18 |
37,797,176 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4243:Pcdhga1
|
UTSW |
18 |
37,796,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4245:Pcdhga1
|
UTSW |
18 |
37,796,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4424:Pcdhga1
|
UTSW |
18 |
37,795,632 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4898:Pcdhga1
|
UTSW |
18 |
37,795,407 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4941:Pcdhga1
|
UTSW |
18 |
37,795,659 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5021:Pcdhga1
|
UTSW |
18 |
37,796,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5765:Pcdhga1
|
UTSW |
18 |
37,796,714 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6176:Pcdhga1
|
UTSW |
18 |
37,797,282 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6380:Pcdhga1
|
UTSW |
18 |
37,796,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Pcdhga1
|
UTSW |
18 |
37,958,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7146:Pcdhga1
|
UTSW |
18 |
37,795,164 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7266:Pcdhga1
|
UTSW |
18 |
37,973,028 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7525:Pcdhga1
|
UTSW |
18 |
37,795,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Pcdhga1
|
UTSW |
18 |
37,882,735 (GRCm39) |
splice site |
probably null |
|
|
R7581:Pcdhga1
|
UTSW |
18 |
37,795,230 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7932:Pcdhga1
|
UTSW |
18 |
37,796,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8330:Pcdhga1
|
UTSW |
18 |
37,796,376 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8385:Pcdhga1
|
UTSW |
18 |
37,795,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8549:Pcdhga1
|
UTSW |
18 |
37,966,386 (GRCm39) |
makesense |
probably null |
|
|
R9147:Pcdhga1
|
UTSW |
18 |
37,796,433 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9148:Pcdhga1
|
UTSW |
18 |
37,796,433 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9192:Pcdhga1
|
UTSW |
18 |
37,973,084 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9336:Pcdhga1
|
UTSW |
18 |
37,795,251 (GRCm39) |
missense |
probably damaging |
0.97 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGACCCCATCTGACCATCTG -3'
(R):5'- TGTTTCTGTTTCCCAACGGG -3'
Sequencing Primer
(F):5'- TGCTGATGGGAGCTCTACC -3'
(R):5'- CCAACGGGGAGCATGGC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation