Mutagenetix > Incidental Mutation

Incidental Mutation 'R1874:Eml6'

211067

Institutional Source

Beutler Lab

Gene Symbol

Eml6

Ensembl Gene

ENSMUSG00000044072

Gene Name

echinoderm microtubule associated protein like 6

Synonyms

MMRRC Submission

039896-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.204) question?

Stock #

R1874 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

29743048-30026033 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 29831136 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Alanine at position 632 (D632A)

Ref Sequence

ENSEMBL: ENSMUSP00000051080 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058902]

AlphaFold

Q5SQM0

Predicted Effect

probably damaging
Transcript: ENSMUST00000058902
AA Change: D632A

PolyPhen 2 Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000051080
Gene: ENSMUSG00000044072
AA Change: D632A

Domain	Start	End	E-Value	Type
low complexity region	36	47	N/A	INTRINSIC
WD40	49	91	1.79e-1	SMART
WD40	94	136	1.42e-4	SMART
WD40	139	178	5.31e-4	SMART
WD40	184	224	8.84e1	SMART
WD40	225	263	3.75e-4	SMART
WD40	313	353	4.69e-5	SMART
WD40	356	394	2.22e0	SMART
WD40	397	436	1.72e0	SMART
WD40	505	546	1.7e2	SMART
WD40	552	592	4.55e-3	SMART
low complexity region	613	625	N/A	INTRINSIC
Pfam:HELP	653	715	1.9e-22	PFAM
WD40	716	757	9.24e-1	SMART
WD40	760	802	6.53e-4	SMART
WD40	805	844	2.98e-1	SMART
WD40	856	891	8.52e1	SMART
WD40	892	929	2.09e-2	SMART
WD40	986	1026	1.18e-1	SMART
WD40	1032	1068	3.44e0	SMART
WD40	1071	1111	2.58e-1	SMART
WD40	1180	1221	9.24e-1	SMART
WD40	1227	1267	3.85e-1	SMART
low complexity region	1280	1291	N/A	INTRINSIC
Pfam:HELP	1329	1402	5e-15	PFAM
WD40	1404	1447	2.66e0	SMART
WD40	1450	1492	1.85e0	SMART
WD40	1495	1534	2.97e0	SMART
WD40	1543	1582	7.1e1	SMART
WD40	1584	1629	9.51e1	SMART
WD40	1675	1715	3.05e-4	SMART
WD40	1718	1758	8.84e1	SMART
WD40	1759	1798	7.16e-1	SMART
WD40	1869	1910	1.53e1	SMART
WD40	1916	1956	4.62e-4	SMART

Meta Mutation Damage Score

0.1238

Coding Region Coverage

1x: 97.5%
3x: 97.0%
10x: 95.8%
20x: 94.1%

Validation Efficiency

96% (105/109)

Allele List at MGI

Other mutations in this stock

Total: 104 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
AA986860	A	G	1: 130,742,691 (GRCm38)	S217G	probably benign	Het
Adrb3	C	A	8: 27,227,563 (GRCm38)	R286L	probably damaging	Het
Akap11	T	A	14: 78,511,866 (GRCm38)	D1027V	probably benign	Het
Ank3	A	T	10: 69,898,083 (GRCm38)	I726F	probably damaging	Het
Ankmy2	T	A	12: 36,165,931 (GRCm38)	D43E	possibly damaging	Het
Ankrd34b	A	G	13: 92,439,556 (GRCm38)	D432G	probably damaging	Het
Ano3	A	C	2: 110,884,872 (GRCm38)	S74A	probably benign	Het
B4galnt4	T	A	7: 141,070,526 (GRCm38)	S769T	probably damaging	Het
Bicral	T	A	17: 46,825,178 (GRCm38)	T369S	probably benign	Het
Blm	A	G	7: 80,497,418 (GRCm38)	L738P	probably damaging	Het
Bpifb3	A	G	2: 153,925,840 (GRCm38)	T278A	probably benign	Het
Bpifb5	A	G	2: 154,227,202 (GRCm38)		probably benign	Het
Brd8	G	C	18: 34,610,474 (GRCm38)	P266R	probably damaging	Het
Btaf1	A	T	19: 36,980,583 (GRCm38)	M587L	probably benign	Het
Casz1	C	G	4: 148,943,211 (GRCm38)	T1015S	probably damaging	Het
Cdh23	A	G	10: 60,436,818 (GRCm38)	I524T	possibly damaging	Het
Celsr3	T	C	9: 108,835,838 (GRCm38)	V1825A	probably benign	Het
Cenpf	A	G	1: 189,683,816 (GRCm38)	L104P	probably damaging	Het
Clasp1	G	T	1: 118,600,585 (GRCm38)		probably null	Het
Coprs	A	G	8: 13,885,112 (GRCm38)	W148R	probably damaging	Het
Cpne1	A	G	2: 156,078,382 (GRCm38)	S168P	probably damaging	Het
Cpxm2	T	C	7: 132,059,834 (GRCm38)	Y408C	probably damaging	Het
Ctnna3	A	G	10: 63,504,107 (GRCm38)	E24G	possibly damaging	Het
Cubn	T	A	2: 13,323,002 (GRCm38)	S2671C	probably damaging	Het
Cyp4f39	T	A	17: 32,483,324 (GRCm38)	F265Y	probably damaging	Het
Dgkq	C	A	5: 108,660,595 (GRCm38)	R34L	probably benign	Het
Dnajc7	C	T	11: 100,599,313 (GRCm38)		probably benign	Het
Fbxl18	G	A	5: 142,886,223 (GRCm38)	A419V	probably damaging	Het
Fbxw22	A	T	9: 109,385,111 (GRCm38)	C212*	probably null	Het
Ffar2	A	G	7: 30,819,414 (GRCm38)		probably null	Het
Fga	A	T	3: 83,032,721 (GRCm38)	T561S	probably damaging	Het
Fry	A	G	5: 150,345,921 (GRCm38)	Y159C	probably damaging	Het
Gal3st1	A	G	11: 3,998,231 (GRCm38)	Y146C	probably damaging	Het
Gapvd1	A	T	2: 34,706,021 (GRCm38)	H788Q	probably damaging	Het
Gimap7	G	A	6: 48,723,515 (GRCm38)	V12I	possibly damaging	Het
Gli2	C	A	1: 119,002,049 (GRCm38)	A43S	possibly damaging	Het
Gm15446	T	C	5: 109,942,553 (GRCm38)	F224L	probably damaging	Het
Gm21738	C	T	14: 19,418,824 (GRCm38)	V35I	possibly damaging	Het
Grhl1	T	C	12: 24,586,156 (GRCm38)		probably benign	Het
Grk6	T	C	13: 55,450,273 (GRCm38)	Y53H	probably damaging	Het
Hcar1	C	T	5: 123,879,265 (GRCm38)	R121K	probably damaging	Het
Hmcn1	A	C	1: 150,720,695 (GRCm38)	S1797A	probably damaging	Het
Hsd17b7	A	T	1: 169,955,993 (GRCm38)	L282Q	possibly damaging	Het
Irs1	TTCTCTGAGTGGCCACAGCGTCT	TTCT	1: 82,289,853 (GRCm38)		probably null	Het
Kif1b	C	T	4: 149,187,632 (GRCm38)	V1571I	probably benign	Het
Lpl	T	A	8: 68,896,619 (GRCm38)	C266S	probably damaging	Het
Mag	G	A	7: 30,909,051 (GRCm38)	H213Y	probably benign	Het
Mansc4	T	G	6: 147,075,190 (GRCm38)	R309S	probably benign	Het
Mlh3	A	G	12: 85,237,513 (GRCm38)		probably null	Het
Mndal	G	A	1: 173,860,367 (GRCm38)		probably benign	Het
Mrgpra2b	T	A	7: 47,463,994 (GRCm38)	E330V	probably damaging	Het
Myh3	A	G	11: 67,093,179 (GRCm38)	I990V	probably benign	Het
Myoz2	A	T	3: 123,026,116 (GRCm38)	S65T	probably damaging	Het
Naa16	T	C	14: 79,355,743 (GRCm38)	E463G	possibly damaging	Het
Nadsyn1	A	G	7: 143,797,844 (GRCm38)	F684S	probably damaging	Het
Notch1	T	C	2: 26,481,579 (GRCm38)	E286G	possibly damaging	Het
Nynrin	A	T	14: 55,863,493 (GRCm38)	I247L	probably benign	Het
Oprm1	A	G	10: 6,789,035 (GRCm38)	H54R	probably benign	Het
Or10g6	T	A	9: 40,022,855 (GRCm38)	I154N	possibly damaging	Het
Or2n1d	C	T	17: 38,335,969 (GRCm38)	P271S	probably damaging	Het
Or51a43	T	C	7: 104,068,129 (GRCm38)	I301V	probably null	Het
P4hb	C	T	11: 120,562,166 (GRCm38)	D483N	probably benign	Het
Pak1	T	C	7: 97,871,580 (GRCm38)	S149P	probably benign	Het
Pars2	T	C	4: 106,653,716 (GRCm38)	F232L	possibly damaging	Het
Pih1d2	A	G	9: 50,620,945 (GRCm38)	M88V	possibly damaging	Het
Pms1	A	T	1: 53,207,233 (GRCm38)	N382K	probably benign	Het
Pnliprp2	G	T	19: 58,763,389 (GRCm38)	V189L	probably benign	Het
Pole	G	A	5: 110,323,664 (GRCm38)	V1425M	possibly damaging	Het
Pot1b	T	A	17: 55,654,805 (GRCm38)	Q591L	probably benign	Het
Ppp1r9a	C	T	6: 4,906,348 (GRCm38)	T301M	possibly damaging	Het
Psg21	T	C	7: 18,650,816 (GRCm38)	E335G	probably benign	Het
Ptpru	T	A	4: 131,769,755 (GRCm38)	M1416L	probably benign	Het
Pxn	T	C	5: 115,544,990 (GRCm38)	V117A	probably damaging	Het
Qsox1	C	T	1: 155,812,639 (GRCm38)	R54H	possibly damaging	Het
Rad1	A	G	15: 10,488,006 (GRCm38)	E42G	probably damaging	Het
Rpp14	A	G	14: 8,090,145 (GRCm38)	Y23C	probably benign	Het
Sdk2	C	T	11: 113,834,956 (GRCm38)	V1156I	probably benign	Het
Serpina3j	G	T	12: 104,319,699 (GRCm38)	R371L	probably benign	Het
Serpinb9d	T	A	13: 33,197,963 (GRCm38)		probably null	Het
Sirt5	C	T	13: 43,370,791 (GRCm38)	S13F	possibly damaging	Het
Slc6a7	T	A	18: 61,001,398 (GRCm38)		probably benign	Het
Slx4	A	G	16: 3,986,848 (GRCm38)	S701P	probably benign	Het
Snx29	A	G	16: 11,367,681 (GRCm38)	T43A	probably benign	Het
Speg	T	C	1: 75,423,906 (GRCm38)	V2570A	probably benign	Het
Srrm4	T	A	5: 116,453,506 (GRCm38)		probably benign	Het
Stk32a	A	G	18: 43,261,316 (GRCm38)	Y110C	probably damaging	Het
Tbc1d31	G	A	15: 57,916,110 (GRCm38)	G73E	probably benign	Het
Thsd7a	A	T	6: 12,555,435 (GRCm38)	I150N	possibly damaging	Het
Tjp1	A	T	7: 65,319,253 (GRCm38)	D699E	probably damaging	Het
Tmem143	A	G	7: 45,916,564 (GRCm38)	D437G	possibly damaging	Het
Tmem45a2	A	G	16: 57,047,084 (GRCm38)	Y85H	possibly damaging	Het
Tmem45b	T	A	9: 31,429,087 (GRCm38)	T7S	probably damaging	Het
Tut4	T	A	4: 108,550,725 (GRCm38)	V1397D	probably damaging	Het
Ube4b	A	G	4: 149,347,971 (GRCm38)	L832P	probably damaging	Het
Ugp2	G	T	11: 21,329,048 (GRCm38)	F379L	probably damaging	Het
Ugt3a2	A	T	15: 9,365,351 (GRCm38)	D350V	probably damaging	Het
Vmn2r8	T	A	5: 108,802,418 (GRCm38)	T188S	possibly damaging	Het
Vwa7	C	G	17: 35,017,112 (GRCm38)	P14R	probably benign	Het
Vwc2	C	A	11: 11,261,495 (GRCm38)	T317K	probably damaging	Het
Vwf	A	T	6: 125,628,372 (GRCm38)	Q906L	probably benign	Het
Wdr49	A	G	3: 75,429,347 (GRCm38)	V351A	probably damaging	Het
Wdr7	A	G	18: 63,728,504 (GRCm38)	S196G	probably benign	Het
Xkr6	C	A	14: 63,798,296 (GRCm38)	A26E	unknown	Het
Zfp955b	T	C	17: 33,305,453 (GRCm38)	I47V	probably benign	Het

Other mutations in Eml6

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01071:Eml6	APN	11	29,850,816 (GRCm38)	critical splice donor site	probably null
IGL01407:Eml6	APN	11	29,755,021 (GRCm38)	nonsense	probably null
IGL01434:Eml6	APN	11	29,819,090 (GRCm38)	missense	probably damaging	1.00
IGL01578:Eml6	APN	11	29,850,870 (GRCm38)	missense	probably benign	0.02
IGL01780:Eml6	APN	11	29,805,175 (GRCm38)	missense	probably benign	0.17
IGL01821:Eml6	APN	11	29,821,699 (GRCm38)	missense	probably benign	0.00
IGL01837:Eml6	APN	11	29,777,055 (GRCm38)	missense	probably benign	0.00
IGL01904:Eml6	APN	11	29,838,613 (GRCm38)	nonsense	probably null
IGL01972:Eml6	APN	11	29,838,451 (GRCm38)	missense	possibly damaging	0.67
IGL02134:Eml6	APN	11	29,759,066 (GRCm38)	missense	probably benign	0.13
IGL02192:Eml6	APN	11	29,805,743 (GRCm38)	missense	probably benign	0.00
IGL02377:Eml6	APN	11	29,777,282 (GRCm38)	missense	probably damaging	0.98
IGL02584:Eml6	APN	11	29,749,387 (GRCm38)	missense	probably damaging	0.99
IGL02587:Eml6	APN	11	29,784,236 (GRCm38)	missense	possibly damaging	0.92
IGL02810:Eml6	APN	11	29,849,016 (GRCm38)	missense	possibly damaging	0.94
IGL02873:Eml6	APN	11	29,880,700 (GRCm38)	missense	probably benign	0.10
IGL02880:Eml6	APN	11	29,749,959 (GRCm38)	missense	probably benign	0.03
IGL03289:Eml6	APN	11	29,795,328 (GRCm38)	missense	possibly damaging	0.49
IGL03301:Eml6	APN	11	29,764,083 (GRCm38)	missense	probably benign	0.18
IGL03386:Eml6	APN	11	29,749,934 (GRCm38)	missense	probably benign
IGL03407:Eml6	APN	11	29,906,330 (GRCm38)	missense	probably damaging	1.00
PIT4453001:Eml6	UTSW	11	29,802,489 (GRCm38)	missense	probably damaging	1.00
R0125:Eml6	UTSW	11	29,882,088 (GRCm38)	missense	probably benign	0.19
R0240:Eml6	UTSW	11	29,792,367 (GRCm38)	missense	possibly damaging	0.84
R0240:Eml6	UTSW	11	29,792,367 (GRCm38)	missense	possibly damaging	0.84
R0271:Eml6	UTSW	11	29,848,949 (GRCm38)	missense	possibly damaging	0.48
R0304:Eml6	UTSW	11	29,777,441 (GRCm38)	missense	probably benign	0.00
R0415:Eml6	UTSW	11	29,749,392 (GRCm38)	missense	possibly damaging	0.84
R0449:Eml6	UTSW	11	29,893,213 (GRCm38)	missense	probably benign	0.01
R0538:Eml6	UTSW	11	29,760,010 (GRCm38)	splice site	probably benign
R0671:Eml6	UTSW	11	29,805,065 (GRCm38)	missense	probably benign	0.00
R0766:Eml6	UTSW	11	29,831,219 (GRCm38)	splice site	probably benign
R0800:Eml6	UTSW	11	29,749,877 (GRCm38)	missense	probably benign	0.08
R0841:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R0879:Eml6	UTSW	11	29,850,816 (GRCm38)	critical splice donor site	probably null
R1061:Eml6	UTSW	11	29,777,267 (GRCm38)	missense	probably damaging	1.00
R1145:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R1145:Eml6	UTSW	11	29,777,430 (GRCm38)	missense	probably benign	0.41
R1172:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1173:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1174:Eml6	UTSW	11	29,749,824 (GRCm38)	missense	possibly damaging	0.54
R1199:Eml6	UTSW	11	29,755,044 (GRCm38)	missense	possibly damaging	0.93
R1311:Eml6	UTSW	11	29,831,088 (GRCm38)	splice site	probably benign
R1312:Eml6	UTSW	11	29,831,219 (GRCm38)	splice site	probably benign
R1355:Eml6	UTSW	11	29,833,085 (GRCm38)	missense	probably benign	0.03
R1370:Eml6	UTSW	11	29,833,085 (GRCm38)	missense	probably benign	0.03
R1457:Eml6	UTSW	11	30,024,459 (GRCm38)	missense	probably damaging	1.00
R1486:Eml6	UTSW	11	29,805,114 (GRCm38)	missense	possibly damaging	0.83
R1511:Eml6	UTSW	11	29,818,374 (GRCm38)	missense	probably damaging	1.00
R1532:Eml6	UTSW	11	29,792,256 (GRCm38)	splice site	probably null
R1642:Eml6	UTSW	11	29,777,001 (GRCm38)	critical splice donor site	probably null
R1682:Eml6	UTSW	11	29,759,065 (GRCm38)	missense	probably benign	0.13
R1687:Eml6	UTSW	11	29,833,187 (GRCm38)	missense	probably damaging	1.00
R1699:Eml6	UTSW	11	29,746,282 (GRCm38)	nonsense	probably null
R1796:Eml6	UTSW	11	29,881,975 (GRCm38)	missense	probably benign	0.19
R1797:Eml6	UTSW	11	29,882,041 (GRCm38)	missense	probably benign	0.09
R1837:Eml6	UTSW	11	29,749,802 (GRCm38)	splice site	probably null
R1967:Eml6	UTSW	11	30,024,545 (GRCm38)	missense	probably damaging	1.00
R1969:Eml6	UTSW	11	29,833,075 (GRCm38)	missense	probably benign
R2007:Eml6	UTSW	11	29,848,814 (GRCm38)	critical splice donor site	probably null
R2012:Eml6	UTSW	11	29,831,128 (GRCm38)	missense	possibly damaging	0.85
R2198:Eml6	UTSW	11	29,850,935 (GRCm38)	missense	probably benign	0.01
R2217:Eml6	UTSW	11	29,818,907 (GRCm38)	missense	probably damaging	1.00
R2218:Eml6	UTSW	11	29,818,907 (GRCm38)	missense	probably damaging	1.00
R2403:Eml6	UTSW	11	29,802,434 (GRCm38)	missense	probably benign	0.05
R2520:Eml6	UTSW	11	29,791,993 (GRCm38)	missense	probably damaging	1.00
R2937:Eml6	UTSW	11	29,833,049 (GRCm38)	splice site	probably benign
R2938:Eml6	UTSW	11	29,833,049 (GRCm38)	splice site	probably benign
R3085:Eml6	UTSW	11	29,809,332 (GRCm38)	missense	probably damaging	0.96
R3236:Eml6	UTSW	11	29,831,097 (GRCm38)	critical splice donor site	probably null
R3738:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R3739:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R3752:Eml6	UTSW	11	29,809,360 (GRCm38)	missense	probably benign	0.06
R3854:Eml6	UTSW	11	29,749,905 (GRCm38)	missense	possibly damaging	0.76
R3941:Eml6	UTSW	11	29,803,167 (GRCm38)	missense	probably damaging	0.98
R4034:Eml6	UTSW	11	29,803,137 (GRCm38)	missense	probably benign	0.20
R4049:Eml6	UTSW	11	29,838,577 (GRCm38)	missense	probably damaging	1.00
R4108:Eml6	UTSW	11	29,805,136 (GRCm38)	missense	probably damaging	0.98
R4657:Eml6	UTSW	11	29,805,108 (GRCm38)	missense	possibly damaging	0.77
R4662:Eml6	UTSW	11	29,777,390 (GRCm38)	missense	probably damaging	1.00
R4665:Eml6	UTSW	11	29,819,007 (GRCm38)	nonsense	probably null
R4721:Eml6	UTSW	11	29,838,525 (GRCm38)	missense	possibly damaging	0.95
R4729:Eml6	UTSW	11	29,833,204 (GRCm38)	missense	probably damaging	1.00
R4766:Eml6	UTSW	11	29,805,757 (GRCm38)	missense	probably benign	0.22
R4810:Eml6	UTSW	11	29,755,011 (GRCm38)	missense	possibly damaging	0.92
R4831:Eml6	UTSW	11	29,777,052 (GRCm38)	nonsense	probably null
R5035:Eml6	UTSW	11	29,854,187 (GRCm38)	missense	probably benign	0.00
R5064:Eml6	UTSW	11	29,749,300 (GRCm38)	missense	probably benign	0.12
R5103:Eml6	UTSW	11	29,850,905 (GRCm38)	missense	possibly damaging	0.65
R5121:Eml6	UTSW	11	29,744,606 (GRCm38)	missense	probably benign	0.03
R5161:Eml6	UTSW	11	30,024,467 (GRCm38)	missense	probably damaging	0.99
R5211:Eml6	UTSW	11	29,854,145 (GRCm38)	missense	probably benign	0.02
R5268:Eml6	UTSW	11	29,803,108 (GRCm38)	missense	probably benign	0.15
R5390:Eml6	UTSW	11	29,760,096 (GRCm38)	missense	probably damaging	1.00
R5529:Eml6	UTSW	11	29,764,126 (GRCm38)	missense	probably benign	0.04
R6239:Eml6	UTSW	11	29,749,275 (GRCm38)	missense	probably damaging	1.00
R6326:Eml6	UTSW	11	29,819,066 (GRCm38)	missense	probably damaging	1.00
R6395:Eml6	UTSW	11	29,809,321 (GRCm38)	missense	probably benign	0.00
R6476:Eml6	UTSW	11	29,791,971 (GRCm38)	critical splice donor site	probably null
R6483:Eml6	UTSW	11	29,749,875 (GRCm38)	missense	probably benign	0.00
R6701:Eml6	UTSW	11	29,785,748 (GRCm38)	missense	probably damaging	0.98
R6753:Eml6	UTSW	11	29,754,987 (GRCm38)	missense	probably damaging	1.00
R6809:Eml6	UTSW	11	29,803,161 (GRCm38)	missense	probably benign	0.23
R6847:Eml6	UTSW	11	29,818,447 (GRCm38)	missense	probably benign	0.00
R6855:Eml6	UTSW	11	29,751,381 (GRCm38)	splice site	probably null
R7168:Eml6	UTSW	11	29,838,529 (GRCm38)	missense	probably benign	0.01
R7175:Eml6	UTSW	11	29,784,231 (GRCm38)	missense	probably benign	0.00
R7305:Eml6	UTSW	11	29,777,258 (GRCm38)	missense	probably benign	0.01
R7615:Eml6	UTSW	11	29,802,501 (GRCm38)	missense	possibly damaging	0.49
R7692:Eml6	UTSW	11	29,753,085 (GRCm38)	missense	probably damaging	0.98
R7980:Eml6	UTSW	11	29,833,205 (GRCm38)	missense	probably damaging	1.00
R8026:Eml6	UTSW	11	29,749,973 (GRCm38)	missense	possibly damaging	0.63
R8046:Eml6	UTSW	11	29,758,981 (GRCm38)	missense	probably damaging	0.99
R8049:Eml6	UTSW	11	29,893,201 (GRCm38)	missense	possibly damaging	0.95
R8114:Eml6	UTSW	11	29,754,910 (GRCm38)	missense	probably damaging	1.00
R8425:Eml6	UTSW	11	29,755,008 (GRCm38)	missense	probably benign	0.00
R8799:Eml6	UTSW	11	29,758,981 (GRCm38)	missense	probably benign	0.11
R8945:Eml6	UTSW	11	29,753,110 (GRCm38)	missense	probably damaging	0.98
R8977:Eml6	UTSW	11	29,784,182 (GRCm38)	missense	possibly damaging	0.59
R8986:Eml6	UTSW	11	29,805,181 (GRCm38)	missense	possibly damaging	0.92
R9088:Eml6	UTSW	11	29,818,424 (GRCm38)	missense	probably damaging	0.96
R9150:Eml6	UTSW	11	29,805,791 (GRCm38)	missense	probably benign	0.15
R9209:Eml6	UTSW	11	29,831,175 (GRCm38)	missense	probably damaging	1.00
R9288:Eml6	UTSW	11	29,838,641 (GRCm38)	critical splice acceptor site	probably null
R9467:Eml6	UTSW	11	29,819,076 (GRCm38)	missense	probably damaging	0.99
R9481:Eml6	UTSW	11	29,838,641 (GRCm38)	critical splice acceptor site	probably null
R9534:Eml6	UTSW	11	29,784,155 (GRCm38)	missense	possibly damaging	0.45
RF037:Eml6	UTSW	11	29,752,549 (GRCm38)	critical splice acceptor site	probably benign
RF039:Eml6	UTSW	11	29,752,551 (GRCm38)	critical splice acceptor site	probably benign

Predicted Primers

PCR Primer
(F):5'- GTTAACCTGCATCCAAAGTCAAG -3'
(R):5'- GGAGGCCAACATATCAGGTTC -3'

Sequencing Primer
(F):5'- CCTGCATCCAAAGTCAAGATATG -3'
(R):5'- GGTTCCAGGCCTGAATTAAATG -3'

Posted On

2014-06-30