Incidental Mutation 'R1874:Btaf1'
| ID |
211106 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Btaf1
|
| Ensembl Gene |
ENSMUSG00000040565 |
| Gene Name |
B-TFIID TATA-box binding protein associated factor 1 |
| Synonyms |
E430027O22Rik |
| MMRRC Submission |
039896-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.963)
|
| Stock # |
R1874 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
36926079-37012752 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 36980583 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 587
(M587L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097093
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099494]
|
| AlphaFold |
E9QAE3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099494
AA Change: M587L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000097093
Gene: ENSMUSG00000040565
AA Change: M587L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
152 |
N/A |
INTRINSIC |
|
PDB:3OC3|B
|
276 |
414 |
3e-6 |
PDB |
|
low complexity region
|
438 |
454 |
N/A |
INTRINSIC |
|
Pfam:DUF3535
|
585 |
1051 |
1.1e-133 |
PFAM |
|
low complexity region
|
1099 |
1110 |
N/A |
INTRINSIC |
|
low complexity region
|
1177 |
1192 |
N/A |
INTRINSIC |
|
DEXDc
|
1261 |
1469 |
3.02e-30 |
SMART |
|
low complexity region
|
1630 |
1641 |
N/A |
INTRINSIC |
|
HELICc
|
1657 |
1743 |
2.22e-19 |
SMART |
|
| Meta Mutation Damage Score |
0.0597 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.8%
- 20x: 94.1%
|
| Validation Efficiency |
96% (105/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]
PHENOTYPE: Embryos homozygous for a gene-trapped allele display growth retardation. Embryos homozygous for an ENU-induced allele show growth retardation, edema, abnormal blood circulation, myocardial trabeculae hypoplasia, and delayed head and brain development. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(40) : Gene trapped(40) |
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| AA986860 |
A |
G |
1: 130,742,691 (GRCm38) |
S217G |
probably benign |
Het |
| Adrb3 |
C |
A |
8: 27,227,563 (GRCm38) |
R286L |
probably damaging |
Het |
| Akap11 |
T |
A |
14: 78,511,866 (GRCm38) |
D1027V |
probably benign |
Het |
| Ank3 |
A |
T |
10: 69,898,083 (GRCm38) |
I726F |
probably damaging |
Het |
| Ankmy2 |
T |
A |
12: 36,165,931 (GRCm38) |
D43E |
possibly damaging |
Het |
| Ankrd34b |
A |
G |
13: 92,439,556 (GRCm38) |
D432G |
probably damaging |
Het |
| Ano3 |
A |
C |
2: 110,884,872 (GRCm38) |
S74A |
probably benign |
Het |
| B4galnt4 |
T |
A |
7: 141,070,526 (GRCm38) |
S769T |
probably damaging |
Het |
| Bicral |
T |
A |
17: 46,825,178 (GRCm38) |
T369S |
probably benign |
Het |
| Blm |
A |
G |
7: 80,497,418 (GRCm38) |
L738P |
probably damaging |
Het |
| Bpifb3 |
A |
G |
2: 153,925,840 (GRCm38) |
T278A |
probably benign |
Het |
| Bpifb5 |
A |
G |
2: 154,227,202 (GRCm38) |
|
probably benign |
Het |
| Brd8 |
G |
C |
18: 34,610,474 (GRCm38) |
P266R |
probably damaging |
Het |
| Casz1 |
C |
G |
4: 148,943,211 (GRCm38) |
T1015S |
probably damaging |
Het |
| Cdh23 |
A |
G |
10: 60,436,818 (GRCm38) |
I524T |
possibly damaging |
Het |
| Celsr3 |
T |
C |
9: 108,835,838 (GRCm38) |
V1825A |
probably benign |
Het |
| Cenpf |
A |
G |
1: 189,683,816 (GRCm38) |
L104P |
probably damaging |
Het |
| Clasp1 |
G |
T |
1: 118,600,585 (GRCm38) |
|
probably null |
Het |
| Coprs |
A |
G |
8: 13,885,112 (GRCm38) |
W148R |
probably damaging |
Het |
| Cpne1 |
A |
G |
2: 156,078,382 (GRCm38) |
S168P |
probably damaging |
Het |
| Cpxm2 |
T |
C |
7: 132,059,834 (GRCm38) |
Y408C |
probably damaging |
Het |
| Ctnna3 |
A |
G |
10: 63,504,107 (GRCm38) |
E24G |
possibly damaging |
Het |
| Cubn |
T |
A |
2: 13,323,002 (GRCm38) |
S2671C |
probably damaging |
Het |
| Cyp4f39 |
T |
A |
17: 32,483,324 (GRCm38) |
F265Y |
probably damaging |
Het |
| Dgkq |
C |
A |
5: 108,660,595 (GRCm38) |
R34L |
probably benign |
Het |
| Dnajc7 |
C |
T |
11: 100,599,313 (GRCm38) |
|
probably benign |
Het |
| Eml6 |
T |
G |
11: 29,831,136 (GRCm38) |
D632A |
probably damaging |
Het |
| Fbxl18 |
G |
A |
5: 142,886,223 (GRCm38) |
A419V |
probably damaging |
Het |
| Fbxw22 |
A |
T |
9: 109,385,111 (GRCm38) |
C212* |
probably null |
Het |
| Ffar2 |
A |
G |
7: 30,819,414 (GRCm38) |
|
probably null |
Het |
| Fga |
A |
T |
3: 83,032,721 (GRCm38) |
T561S |
probably damaging |
Het |
| Fry |
A |
G |
5: 150,345,921 (GRCm38) |
Y159C |
probably damaging |
Het |
| Gal3st1 |
A |
G |
11: 3,998,231 (GRCm38) |
Y146C |
probably damaging |
Het |
| Gapvd1 |
A |
T |
2: 34,706,021 (GRCm38) |
H788Q |
probably damaging |
Het |
| Gimap7 |
G |
A |
6: 48,723,515 (GRCm38) |
V12I |
possibly damaging |
Het |
| Gli2 |
C |
A |
1: 119,002,049 (GRCm38) |
A43S |
possibly damaging |
Het |
| Gm15446 |
T |
C |
5: 109,942,553 (GRCm38) |
F224L |
probably damaging |
Het |
| Gm21738 |
C |
T |
14: 19,418,824 (GRCm38) |
V35I |
possibly damaging |
Het |
| Grhl1 |
T |
C |
12: 24,586,156 (GRCm38) |
|
probably benign |
Het |
| Grk6 |
T |
C |
13: 55,450,273 (GRCm38) |
Y53H |
probably damaging |
Het |
| Hcar1 |
C |
T |
5: 123,879,265 (GRCm38) |
R121K |
probably damaging |
Het |
| Hmcn1 |
A |
C |
1: 150,720,695 (GRCm38) |
S1797A |
probably damaging |
Het |
| Hsd17b7 |
A |
T |
1: 169,955,993 (GRCm38) |
L282Q |
possibly damaging |
Het |
| Irs1 |
TTCTCTGAGTGGCCACAGCGTCT |
TTCT |
1: 82,289,853 (GRCm38) |
|
probably null |
Het |
| Kif1b |
C |
T |
4: 149,187,632 (GRCm38) |
V1571I |
probably benign |
Het |
| Lpl |
T |
A |
8: 68,896,619 (GRCm38) |
C266S |
probably damaging |
Het |
| Mag |
G |
A |
7: 30,909,051 (GRCm38) |
H213Y |
probably benign |
Het |
| Mansc4 |
T |
G |
6: 147,075,190 (GRCm38) |
R309S |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,237,513 (GRCm38) |
|
probably null |
Het |
| Mndal |
G |
A |
1: 173,860,367 (GRCm38) |
|
probably benign |
Het |
| Mrgpra2b |
T |
A |
7: 47,463,994 (GRCm38) |
E330V |
probably damaging |
Het |
| Myh3 |
A |
G |
11: 67,093,179 (GRCm38) |
I990V |
probably benign |
Het |
| Myoz2 |
A |
T |
3: 123,026,116 (GRCm38) |
S65T |
probably damaging |
Het |
| Naa16 |
T |
C |
14: 79,355,743 (GRCm38) |
E463G |
possibly damaging |
Het |
| Nadsyn1 |
A |
G |
7: 143,797,844 (GRCm38) |
F684S |
probably damaging |
Het |
| Notch1 |
T |
C |
2: 26,481,579 (GRCm38) |
E286G |
possibly damaging |
Het |
| Nynrin |
A |
T |
14: 55,863,493 (GRCm38) |
I247L |
probably benign |
Het |
| Olfr136 |
C |
T |
17: 38,335,969 (GRCm38) |
P271S |
probably damaging |
Het |
| Olfr644 |
T |
C |
7: 104,068,129 (GRCm38) |
I301V |
probably null |
Het |
| Olfr981 |
T |
A |
9: 40,022,855 (GRCm38) |
I154N |
possibly damaging |
Het |
| Oprm1 |
A |
G |
10: 6,789,035 (GRCm38) |
H54R |
probably benign |
Het |
| P4hb |
C |
T |
11: 120,562,166 (GRCm38) |
D483N |
probably benign |
Het |
| Pak1 |
T |
C |
7: 97,871,580 (GRCm38) |
S149P |
probably benign |
Het |
| Pars2 |
T |
C |
4: 106,653,716 (GRCm38) |
F232L |
possibly damaging |
Het |
| Pih1d2 |
A |
G |
9: 50,620,945 (GRCm38) |
M88V |
possibly damaging |
Het |
| Pms1 |
A |
T |
1: 53,207,233 (GRCm38) |
N382K |
probably benign |
Het |
| Pnliprp2 |
G |
T |
19: 58,763,389 (GRCm38) |
V189L |
probably benign |
Het |
| Pole |
G |
A |
5: 110,323,664 (GRCm38) |
V1425M |
possibly damaging |
Het |
| Pot1b |
T |
A |
17: 55,654,805 (GRCm38) |
Q591L |
probably benign |
Het |
| Ppp1r9a |
C |
T |
6: 4,906,348 (GRCm38) |
T301M |
possibly damaging |
Het |
| Psg21 |
T |
C |
7: 18,650,816 (GRCm38) |
E335G |
probably benign |
Het |
| Ptpru |
T |
A |
4: 131,769,755 (GRCm38) |
M1416L |
probably benign |
Het |
| Pxn |
T |
C |
5: 115,544,990 (GRCm38) |
V117A |
probably damaging |
Het |
| Qsox1 |
C |
T |
1: 155,812,639 (GRCm38) |
R54H |
possibly damaging |
Het |
| Rad1 |
A |
G |
15: 10,488,006 (GRCm38) |
E42G |
probably damaging |
Het |
| Rpp14 |
A |
G |
14: 8,090,145 (GRCm38) |
Y23C |
probably benign |
Het |
| Sdk2 |
C |
T |
11: 113,834,956 (GRCm38) |
V1156I |
probably benign |
Het |
| Serpina3j |
G |
T |
12: 104,319,699 (GRCm38) |
R371L |
probably benign |
Het |
| Serpinb9d |
T |
A |
13: 33,197,963 (GRCm38) |
|
probably null |
Het |
| Sirt5 |
C |
T |
13: 43,370,791 (GRCm38) |
S13F |
possibly damaging |
Het |
| Slc6a7 |
T |
A |
18: 61,001,398 (GRCm38) |
|
probably benign |
Het |
| Slx4 |
A |
G |
16: 3,986,848 (GRCm38) |
S701P |
probably benign |
Het |
| Snx29 |
A |
G |
16: 11,367,681 (GRCm38) |
T43A |
probably benign |
Het |
| Speg |
T |
C |
1: 75,423,906 (GRCm38) |
V2570A |
probably benign |
Het |
| Srrm4 |
T |
A |
5: 116,453,506 (GRCm38) |
|
probably benign |
Het |
| Stk32a |
A |
G |
18: 43,261,316 (GRCm38) |
Y110C |
probably damaging |
Het |
| Tbc1d31 |
G |
A |
15: 57,916,110 (GRCm38) |
G73E |
probably benign |
Het |
| Thsd7a |
A |
T |
6: 12,555,435 (GRCm38) |
I150N |
possibly damaging |
Het |
| Tjp1 |
A |
T |
7: 65,319,253 (GRCm38) |
D699E |
probably damaging |
Het |
| Tmem143 |
A |
G |
7: 45,916,564 (GRCm38) |
D437G |
possibly damaging |
Het |
| Tmem45a2 |
A |
G |
16: 57,047,084 (GRCm38) |
Y85H |
possibly damaging |
Het |
| Tmem45b |
T |
A |
9: 31,429,087 (GRCm38) |
T7S |
probably damaging |
Het |
| Ube4b |
A |
G |
4: 149,347,971 (GRCm38) |
L832P |
probably damaging |
Het |
| Ugp2 |
G |
T |
11: 21,329,048 (GRCm38) |
F379L |
probably damaging |
Het |
| Ugt3a2 |
A |
T |
15: 9,365,351 (GRCm38) |
D350V |
probably damaging |
Het |
| Vmn2r8 |
T |
A |
5: 108,802,418 (GRCm38) |
T188S |
possibly damaging |
Het |
| Vwa7 |
C |
G |
17: 35,017,112 (GRCm38) |
P14R |
probably benign |
Het |
| Vwc2 |
C |
A |
11: 11,261,495 (GRCm38) |
T317K |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,628,372 (GRCm38) |
Q906L |
probably benign |
Het |
| Wdr49 |
A |
G |
3: 75,429,347 (GRCm38) |
V351A |
probably damaging |
Het |
| Wdr7 |
A |
G |
18: 63,728,504 (GRCm38) |
S196G |
probably benign |
Het |
| Xkr6 |
C |
A |
14: 63,798,296 (GRCm38) |
A26E |
unknown |
Het |
| Zcchc11 |
T |
A |
4: 108,550,725 (GRCm38) |
V1397D |
probably damaging |
Het |
| Zfp955b |
T |
C |
17: 33,305,453 (GRCm38) |
I47V |
probably benign |
Het |
|
| Other mutations in Btaf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Btaf1
|
APN |
19 |
37,009,702 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00535:Btaf1
|
APN |
19 |
36,997,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00574:Btaf1
|
APN |
19 |
36,969,930 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL00969:Btaf1
|
APN |
19 |
37,011,252 (GRCm38) |
splice site |
probably benign |
|
|
IGL01325:Btaf1
|
APN |
19 |
37,004,649 (GRCm38) |
splice site |
probably benign |
|
|
IGL01399:Btaf1
|
APN |
19 |
37,000,170 (GRCm38) |
nonsense |
probably null |
|
|
IGL02024:Btaf1
|
APN |
19 |
36,992,426 (GRCm38) |
splice site |
probably benign |
|
|
IGL02471:Btaf1
|
APN |
19 |
37,000,192 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02664:Btaf1
|
APN |
19 |
36,978,428 (GRCm38) |
splice site |
probably benign |
|
|
IGL02898:Btaf1
|
APN |
19 |
36,969,068 (GRCm38) |
missense |
probably benign |
|
|
IGL02995:Btaf1
|
APN |
19 |
36,981,135 (GRCm38) |
splice site |
probably benign |
|
|
IGL03023:Btaf1
|
APN |
19 |
37,010,015 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL03188:Btaf1
|
APN |
19 |
36,949,108 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
IGL03353:Btaf1
|
APN |
19 |
36,992,500 (GRCm38) |
missense |
probably damaging |
1.00 |
|
freudenberg
|
UTSW |
19 |
36,988,173 (GRCm38) |
critical splice donor site |
probably null |
|
|
Galanos
|
UTSW |
19 |
36,949,102 (GRCm38) |
missense |
probably damaging |
1.00 |
|
3-1:Btaf1
|
UTSW |
19 |
37,010,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0013:Btaf1
|
UTSW |
19 |
36,958,373 (GRCm38) |
missense |
probably benign |
|
|
R0048:Btaf1
|
UTSW |
19 |
37,003,524 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0117:Btaf1
|
UTSW |
19 |
36,969,968 (GRCm38) |
missense |
probably benign |
0.06 |
|
R0207:Btaf1
|
UTSW |
19 |
37,009,648 (GRCm38) |
nonsense |
probably null |
|
|
R0310:Btaf1
|
UTSW |
19 |
37,004,534 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0377:Btaf1
|
UTSW |
19 |
36,989,002 (GRCm38) |
missense |
probably benign |
|
|
R0419:Btaf1
|
UTSW |
19 |
36,945,229 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0440:Btaf1
|
UTSW |
19 |
36,986,653 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0532:Btaf1
|
UTSW |
19 |
36,951,186 (GRCm38) |
splice site |
probably benign |
|
|
R0612:Btaf1
|
UTSW |
19 |
36,969,137 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0731:Btaf1
|
UTSW |
19 |
36,997,495 (GRCm38) |
splice site |
probably null |
|
|
R0780:Btaf1
|
UTSW |
19 |
36,988,922 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0919:Btaf1
|
UTSW |
19 |
36,990,743 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1104:Btaf1
|
UTSW |
19 |
37,004,602 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1263:Btaf1
|
UTSW |
19 |
36,956,524 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1325:Btaf1
|
UTSW |
19 |
36,969,162 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1447:Btaf1
|
UTSW |
19 |
36,992,454 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1554:Btaf1
|
UTSW |
19 |
36,996,598 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1649:Btaf1
|
UTSW |
19 |
36,981,722 (GRCm38) |
missense |
probably benign |
|
|
R1715:Btaf1
|
UTSW |
19 |
36,969,121 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1733:Btaf1
|
UTSW |
19 |
36,994,962 (GRCm38) |
missense |
probably benign |
|
|
R1764:Btaf1
|
UTSW |
19 |
36,951,118 (GRCm38) |
missense |
probably benign |
0.12 |
|
R1911:Btaf1
|
UTSW |
19 |
36,986,630 (GRCm38) |
missense |
probably benign |
|
|
R1933:Btaf1
|
UTSW |
19 |
36,972,957 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2080:Btaf1
|
UTSW |
19 |
36,951,148 (GRCm38) |
missense |
probably benign |
0.09 |
|
R2483:Btaf1
|
UTSW |
19 |
36,981,086 (GRCm38) |
missense |
probably benign |
0.02 |
|
R2510:Btaf1
|
UTSW |
19 |
37,002,445 (GRCm38) |
missense |
probably benign |
0.08 |
|
R3623:Btaf1
|
UTSW |
19 |
36,981,086 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3624:Btaf1
|
UTSW |
19 |
36,981,086 (GRCm38) |
missense |
probably benign |
0.02 |
|
R3801:Btaf1
|
UTSW |
19 |
36,988,973 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3801:Btaf1
|
UTSW |
19 |
36,986,548 (GRCm38) |
missense |
probably benign |
|
|
R3802:Btaf1
|
UTSW |
19 |
36,988,973 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3802:Btaf1
|
UTSW |
19 |
36,986,548 (GRCm38) |
missense |
probably benign |
|
|
R3803:Btaf1
|
UTSW |
19 |
36,988,973 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3803:Btaf1
|
UTSW |
19 |
36,986,548 (GRCm38) |
missense |
probably benign |
|
|
R4077:Btaf1
|
UTSW |
19 |
36,986,479 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4079:Btaf1
|
UTSW |
19 |
36,986,479 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4133:Btaf1
|
UTSW |
19 |
36,961,738 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4673:Btaf1
|
UTSW |
19 |
36,978,372 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4731:Btaf1
|
UTSW |
19 |
36,981,078 (GRCm38) |
missense |
probably benign |
0.03 |
|
R4796:Btaf1
|
UTSW |
19 |
36,956,428 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R4824:Btaf1
|
UTSW |
19 |
36,981,048 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R4835:Btaf1
|
UTSW |
19 |
37,002,458 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4837:Btaf1
|
UTSW |
19 |
36,966,785 (GRCm38) |
missense |
probably benign |
|
|
R4925:Btaf1
|
UTSW |
19 |
37,011,333 (GRCm38) |
missense |
probably benign |
|
|
R4968:Btaf1
|
UTSW |
19 |
36,969,951 (GRCm38) |
missense |
probably null |
0.71 |
|
R4976:Btaf1
|
UTSW |
19 |
36,986,579 (GRCm38) |
missense |
probably benign |
|
|
R5001:Btaf1
|
UTSW |
19 |
36,986,652 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R5037:Btaf1
|
UTSW |
19 |
37,003,531 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5039:Btaf1
|
UTSW |
19 |
36,990,762 (GRCm38) |
missense |
probably benign |
|
|
R5211:Btaf1
|
UTSW |
19 |
36,996,562 (GRCm38) |
missense |
probably benign |
0.32 |
|
R5422:Btaf1
|
UTSW |
19 |
36,951,107 (GRCm38) |
missense |
probably benign |
0.09 |
|
R5429:Btaf1
|
UTSW |
19 |
36,994,857 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R5530:Btaf1
|
UTSW |
19 |
36,990,775 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R5582:Btaf1
|
UTSW |
19 |
36,988,173 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5654:Btaf1
|
UTSW |
19 |
36,983,615 (GRCm38) |
missense |
probably benign |
0.35 |
|
R5744:Btaf1
|
UTSW |
19 |
37,004,490 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6082:Btaf1
|
UTSW |
19 |
36,983,542 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6243:Btaf1
|
UTSW |
19 |
36,981,120 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6291:Btaf1
|
UTSW |
19 |
36,973,008 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6502:Btaf1
|
UTSW |
19 |
36,983,617 (GRCm38) |
missense |
probably benign |
|
|
R7034:Btaf1
|
UTSW |
19 |
37,004,469 (GRCm38) |
missense |
probably benign |
|
|
R7036:Btaf1
|
UTSW |
19 |
37,004,469 (GRCm38) |
missense |
probably benign |
|
|
R7085:Btaf1
|
UTSW |
19 |
36,972,918 (GRCm38) |
missense |
probably benign |
|
|
R7097:Btaf1
|
UTSW |
19 |
36,949,102 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7248:Btaf1
|
UTSW |
19 |
36,945,314 (GRCm38) |
missense |
possibly damaging |
0.54 |
|
R7386:Btaf1
|
UTSW |
19 |
36,958,382 (GRCm38) |
missense |
probably benign |
0.02 |
|
R7402:Btaf1
|
UTSW |
19 |
37,003,515 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7452:Btaf1
|
UTSW |
19 |
36,969,127 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7493:Btaf1
|
UTSW |
19 |
37,009,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7513:Btaf1
|
UTSW |
19 |
36,978,403 (GRCm38) |
missense |
probably benign |
0.30 |
|
R7888:Btaf1
|
UTSW |
19 |
36,965,636 (GRCm38) |
missense |
probably benign |
0.10 |
|
R7944:Btaf1
|
UTSW |
19 |
36,949,165 (GRCm38) |
missense |
probably benign |
|
|
R8062:Btaf1
|
UTSW |
19 |
36,992,465 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8559:Btaf1
|
UTSW |
19 |
36,986,873 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8793:Btaf1
|
UTSW |
19 |
36,981,029 (GRCm38) |
missense |
probably benign |
0.21 |
|
R8855:Btaf1
|
UTSW |
19 |
36,958,501 (GRCm38) |
missense |
probably benign |
|
|
R8866:Btaf1
|
UTSW |
19 |
36,958,501 (GRCm38) |
missense |
probably benign |
|
|
R9016:Btaf1
|
UTSW |
19 |
36,994,305 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9028:Btaf1
|
UTSW |
19 |
36,969,108 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9109:Btaf1
|
UTSW |
19 |
36,986,714 (GRCm38) |
missense |
probably benign |
|
|
R9172:Btaf1
|
UTSW |
19 |
37,000,230 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9298:Btaf1
|
UTSW |
19 |
36,986,714 (GRCm38) |
missense |
probably benign |
|
|
R9717:Btaf1
|
UTSW |
19 |
36,945,246 (GRCm38) |
missense |
probably benign |
0.28 |
|
W0251:Btaf1
|
UTSW |
19 |
37,003,504 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0027:Btaf1
|
UTSW |
19 |
36,949,096 (GRCm38) |
nonsense |
probably null |
|
|
Z1088:Btaf1
|
UTSW |
19 |
36,986,618 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGGTGCTCTTAACCACTG -3'
(R):5'- GCTGAACACAGAAATACCACGTTTC -3'
Sequencing Primer
(F):5'- TGAACCATCTCTCCAGGCG -3'
(R):5'- AGAAATACCACGTTTCTCTACCC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation