Incidental Mutation 'R1874:Btaf1'
| ID |
211106 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Btaf1
|
| Ensembl Gene |
ENSMUSG00000040565 |
| Gene Name |
B-TFIID TATA-box binding protein associated factor 1 |
| Synonyms |
E430027O22Rik |
| MMRRC Submission |
039896-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.965)
|
| Stock # |
R1874 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
19 |
| Chromosomal Location |
36903479-36990152 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 36957983 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 587
(M587L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097093
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099494]
|
| AlphaFold |
E9QAE3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099494
AA Change: M587L
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000097093
Gene: ENSMUSG00000040565
AA Change: M587L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
87 |
98 |
N/A |
INTRINSIC |
|
low complexity region
|
143 |
152 |
N/A |
INTRINSIC |
|
PDB:3OC3|B
|
276 |
414 |
3e-6 |
PDB |
|
low complexity region
|
438 |
454 |
N/A |
INTRINSIC |
|
Pfam:DUF3535
|
585 |
1051 |
1.1e-133 |
PFAM |
|
low complexity region
|
1099 |
1110 |
N/A |
INTRINSIC |
|
low complexity region
|
1177 |
1192 |
N/A |
INTRINSIC |
|
DEXDc
|
1261 |
1469 |
3.02e-30 |
SMART |
|
low complexity region
|
1630 |
1641 |
N/A |
INTRINSIC |
|
HELICc
|
1657 |
1743 |
2.22e-19 |
SMART |
|
| Meta Mutation Damage Score |
0.0597 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.8%
- 20x: 94.1%
|
| Validation Efficiency |
96% (105/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]
PHENOTYPE: Embryos homozygous for a gene-trapped allele display growth retardation. Embryos homozygous for an ENU-induced allele show growth retardation, edema, abnormal blood circulation, myocardial trabeculae hypoplasia, and delayed head and brain development. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(40) : Gene trapped(40) |
| Other mutations in this stock |
Total: 104 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| AA986860 |
A |
G |
1: 130,670,428 (GRCm39) |
S217G |
probably benign |
Het |
| Adrb3 |
C |
A |
8: 27,717,591 (GRCm39) |
R286L |
probably damaging |
Het |
| Akap11 |
T |
A |
14: 78,749,306 (GRCm39) |
D1027V |
probably benign |
Het |
| Ank3 |
A |
T |
10: 69,733,913 (GRCm39) |
I726F |
probably damaging |
Het |
| Ankmy2 |
T |
A |
12: 36,215,930 (GRCm39) |
D43E |
possibly damaging |
Het |
| Ankrd34b |
A |
G |
13: 92,576,064 (GRCm39) |
D432G |
probably damaging |
Het |
| Ano3 |
A |
C |
2: 110,715,217 (GRCm39) |
S74A |
probably benign |
Het |
| B4galnt4 |
T |
A |
7: 140,650,439 (GRCm39) |
S769T |
probably damaging |
Het |
| Bicral |
T |
A |
17: 47,136,104 (GRCm39) |
T369S |
probably benign |
Het |
| Blm |
A |
G |
7: 80,147,166 (GRCm39) |
L738P |
probably damaging |
Het |
| Bpifb3 |
A |
G |
2: 153,767,760 (GRCm39) |
T278A |
probably benign |
Het |
| Bpifb5 |
A |
G |
2: 154,069,122 (GRCm39) |
|
probably benign |
Het |
| Brd8 |
G |
C |
18: 34,743,527 (GRCm39) |
P266R |
probably damaging |
Het |
| Casz1 |
C |
G |
4: 149,027,668 (GRCm39) |
T1015S |
probably damaging |
Het |
| Cdh23 |
A |
G |
10: 60,272,597 (GRCm39) |
I524T |
possibly damaging |
Het |
| Celsr3 |
T |
C |
9: 108,713,037 (GRCm39) |
V1825A |
probably benign |
Het |
| Cenpf |
A |
G |
1: 189,416,013 (GRCm39) |
L104P |
probably damaging |
Het |
| Clasp1 |
G |
T |
1: 118,528,315 (GRCm39) |
|
probably null |
Het |
| Coprs |
A |
G |
8: 13,935,112 (GRCm39) |
W148R |
probably damaging |
Het |
| Cpne1 |
A |
G |
2: 155,920,302 (GRCm39) |
S168P |
probably damaging |
Het |
| Cpxm2 |
T |
C |
7: 131,661,563 (GRCm39) |
Y408C |
probably damaging |
Het |
| Ctnna3 |
A |
G |
10: 63,339,886 (GRCm39) |
E24G |
possibly damaging |
Het |
| Cubn |
T |
A |
2: 13,327,813 (GRCm39) |
S2671C |
probably damaging |
Het |
| Cyp4f39 |
T |
A |
17: 32,702,298 (GRCm39) |
F265Y |
probably damaging |
Het |
| Dgkq |
C |
A |
5: 108,808,461 (GRCm39) |
R34L |
probably benign |
Het |
| Dnajc7 |
C |
T |
11: 100,490,139 (GRCm39) |
|
probably benign |
Het |
| Eml6 |
T |
G |
11: 29,781,136 (GRCm39) |
D632A |
probably damaging |
Het |
| Fbxl18 |
G |
A |
5: 142,871,978 (GRCm39) |
A419V |
probably damaging |
Het |
| Fbxw22 |
A |
T |
9: 109,214,179 (GRCm39) |
C212* |
probably null |
Het |
| Ffar2 |
A |
G |
7: 30,518,839 (GRCm39) |
|
probably null |
Het |
| Fga |
A |
T |
3: 82,940,028 (GRCm39) |
T561S |
probably damaging |
Het |
| Fry |
A |
G |
5: 150,269,386 (GRCm39) |
Y159C |
probably damaging |
Het |
| Gal3st1 |
A |
G |
11: 3,948,231 (GRCm39) |
Y146C |
probably damaging |
Het |
| Gapvd1 |
A |
T |
2: 34,596,033 (GRCm39) |
H788Q |
probably damaging |
Het |
| Gimap7 |
G |
A |
6: 48,700,449 (GRCm39) |
V12I |
possibly damaging |
Het |
| Gli2 |
C |
A |
1: 118,929,779 (GRCm39) |
A43S |
possibly damaging |
Het |
| Gm15446 |
T |
C |
5: 110,090,419 (GRCm39) |
F224L |
probably damaging |
Het |
| Gm21738 |
C |
T |
14: 19,418,824 (GRCm38) |
V35I |
possibly damaging |
Het |
| Grhl1 |
T |
C |
12: 24,636,155 (GRCm39) |
|
probably benign |
Het |
| Grk6 |
T |
C |
13: 55,598,086 (GRCm39) |
Y53H |
probably damaging |
Het |
| Hcar1 |
C |
T |
5: 124,017,328 (GRCm39) |
R121K |
probably damaging |
Het |
| Hmcn1 |
A |
C |
1: 150,596,446 (GRCm39) |
S1797A |
probably damaging |
Het |
| Hsd17b7 |
A |
T |
1: 169,783,562 (GRCm39) |
L282Q |
possibly damaging |
Het |
| Irs1 |
TTCTCTGAGTGGCCACAGCGTCT |
TTCT |
1: 82,267,574 (GRCm39) |
|
probably null |
Het |
| Kif1b |
C |
T |
4: 149,272,089 (GRCm39) |
V1571I |
probably benign |
Het |
| Lpl |
T |
A |
8: 69,349,271 (GRCm39) |
C266S |
probably damaging |
Het |
| Mag |
G |
A |
7: 30,608,476 (GRCm39) |
H213Y |
probably benign |
Het |
| Mansc4 |
T |
G |
6: 146,976,688 (GRCm39) |
R309S |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,284,287 (GRCm39) |
|
probably null |
Het |
| Mndal |
G |
A |
1: 173,687,933 (GRCm39) |
|
probably benign |
Het |
| Mrgpra2b |
T |
A |
7: 47,113,742 (GRCm39) |
E330V |
probably damaging |
Het |
| Myh3 |
A |
G |
11: 66,984,005 (GRCm39) |
I990V |
probably benign |
Het |
| Myoz2 |
A |
T |
3: 122,819,765 (GRCm39) |
S65T |
probably damaging |
Het |
| Naa16 |
T |
C |
14: 79,593,183 (GRCm39) |
E463G |
possibly damaging |
Het |
| Nadsyn1 |
A |
G |
7: 143,351,581 (GRCm39) |
F684S |
probably damaging |
Het |
| Notch1 |
T |
C |
2: 26,371,591 (GRCm39) |
E286G |
possibly damaging |
Het |
| Nynrin |
A |
T |
14: 56,100,950 (GRCm39) |
I247L |
probably benign |
Het |
| Oprm1 |
A |
G |
10: 6,739,035 (GRCm39) |
H54R |
probably benign |
Het |
| Or10g6 |
T |
A |
9: 39,934,151 (GRCm39) |
I154N |
possibly damaging |
Het |
| Or2n1d |
C |
T |
17: 38,646,860 (GRCm39) |
P271S |
probably damaging |
Het |
| Or51a43 |
T |
C |
7: 103,717,336 (GRCm39) |
I301V |
probably null |
Het |
| P4hb |
C |
T |
11: 120,452,992 (GRCm39) |
D483N |
probably benign |
Het |
| Pak1 |
T |
C |
7: 97,520,787 (GRCm39) |
S149P |
probably benign |
Het |
| Pars2 |
T |
C |
4: 106,510,913 (GRCm39) |
F232L |
possibly damaging |
Het |
| Pih1d2 |
A |
G |
9: 50,532,245 (GRCm39) |
M88V |
possibly damaging |
Het |
| Pms1 |
A |
T |
1: 53,246,392 (GRCm39) |
N382K |
probably benign |
Het |
| Pnliprp2 |
G |
T |
19: 58,751,821 (GRCm39) |
V189L |
probably benign |
Het |
| Pole |
G |
A |
5: 110,471,530 (GRCm39) |
V1425M |
possibly damaging |
Het |
| Pot1b |
T |
A |
17: 55,961,805 (GRCm39) |
Q591L |
probably benign |
Het |
| Ppp1r9a |
C |
T |
6: 4,906,348 (GRCm39) |
T301M |
possibly damaging |
Het |
| Psg21 |
T |
C |
7: 18,384,741 (GRCm39) |
E335G |
probably benign |
Het |
| Ptpru |
T |
A |
4: 131,497,066 (GRCm39) |
M1416L |
probably benign |
Het |
| Pxn |
T |
C |
5: 115,683,049 (GRCm39) |
V117A |
probably damaging |
Het |
| Qsox1 |
C |
T |
1: 155,688,385 (GRCm39) |
R54H |
possibly damaging |
Het |
| Rad1 |
A |
G |
15: 10,488,092 (GRCm39) |
E42G |
probably damaging |
Het |
| Rpp14 |
A |
G |
14: 8,090,145 (GRCm38) |
Y23C |
probably benign |
Het |
| Sdk2 |
C |
T |
11: 113,725,782 (GRCm39) |
V1156I |
probably benign |
Het |
| Serpina3j |
G |
T |
12: 104,285,958 (GRCm39) |
R371L |
probably benign |
Het |
| Serpinb9d |
T |
A |
13: 33,381,946 (GRCm39) |
|
probably null |
Het |
| Sirt5 |
C |
T |
13: 43,524,267 (GRCm39) |
S13F |
possibly damaging |
Het |
| Slc6a7 |
T |
A |
18: 61,134,470 (GRCm39) |
|
probably benign |
Het |
| Slx4 |
A |
G |
16: 3,804,712 (GRCm39) |
S701P |
probably benign |
Het |
| Snx29 |
A |
G |
16: 11,185,545 (GRCm39) |
T43A |
probably benign |
Het |
| Speg |
T |
C |
1: 75,400,550 (GRCm39) |
V2570A |
probably benign |
Het |
| Srrm4 |
T |
A |
5: 116,591,565 (GRCm39) |
|
probably benign |
Het |
| Stk32a |
A |
G |
18: 43,394,381 (GRCm39) |
Y110C |
probably damaging |
Het |
| Tbc1d31 |
G |
A |
15: 57,779,506 (GRCm39) |
G73E |
probably benign |
Het |
| Thsd7a |
A |
T |
6: 12,555,434 (GRCm39) |
I150N |
possibly damaging |
Het |
| Tjp1 |
A |
T |
7: 64,969,001 (GRCm39) |
D699E |
probably damaging |
Het |
| Tmem143 |
A |
G |
7: 45,565,988 (GRCm39) |
D437G |
possibly damaging |
Het |
| Tmem45a2 |
A |
G |
16: 56,867,447 (GRCm39) |
Y85H |
possibly damaging |
Het |
| Tmem45b |
T |
A |
9: 31,340,383 (GRCm39) |
T7S |
probably damaging |
Het |
| Tut4 |
T |
A |
4: 108,407,922 (GRCm39) |
V1397D |
probably damaging |
Het |
| Ube4b |
A |
G |
4: 149,432,428 (GRCm39) |
L832P |
probably damaging |
Het |
| Ugp2 |
G |
T |
11: 21,279,048 (GRCm39) |
F379L |
probably damaging |
Het |
| Ugt3a1 |
A |
T |
15: 9,365,437 (GRCm39) |
D350V |
probably damaging |
Het |
| Vmn2r8 |
T |
A |
5: 108,950,284 (GRCm39) |
T188S |
possibly damaging |
Het |
| Vwa7 |
C |
G |
17: 35,236,088 (GRCm39) |
P14R |
probably benign |
Het |
| Vwc2 |
C |
A |
11: 11,211,495 (GRCm39) |
T317K |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,605,335 (GRCm39) |
Q906L |
probably benign |
Het |
| Wdr49 |
A |
G |
3: 75,336,654 (GRCm39) |
V351A |
probably damaging |
Het |
| Wdr7 |
A |
G |
18: 63,861,575 (GRCm39) |
S196G |
probably benign |
Het |
| Xkr6 |
C |
A |
14: 64,035,745 (GRCm39) |
A26E |
unknown |
Het |
| Zfp955b |
T |
C |
17: 33,524,427 (GRCm39) |
I47V |
probably benign |
Het |
|
| Other mutations in Btaf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Btaf1
|
APN |
19 |
36,987,102 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00535:Btaf1
|
APN |
19 |
36,974,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00574:Btaf1
|
APN |
19 |
36,947,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00969:Btaf1
|
APN |
19 |
36,988,652 (GRCm39) |
splice site |
probably benign |
|
|
IGL01325:Btaf1
|
APN |
19 |
36,982,049 (GRCm39) |
splice site |
probably benign |
|
|
IGL01399:Btaf1
|
APN |
19 |
36,977,570 (GRCm39) |
nonsense |
probably null |
|
|
IGL02024:Btaf1
|
APN |
19 |
36,969,826 (GRCm39) |
splice site |
probably benign |
|
|
IGL02471:Btaf1
|
APN |
19 |
36,977,592 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02664:Btaf1
|
APN |
19 |
36,955,828 (GRCm39) |
splice site |
probably benign |
|
|
IGL02898:Btaf1
|
APN |
19 |
36,946,468 (GRCm39) |
missense |
probably benign |
|
|
IGL02995:Btaf1
|
APN |
19 |
36,958,535 (GRCm39) |
splice site |
probably benign |
|
|
IGL03023:Btaf1
|
APN |
19 |
36,987,415 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03188:Btaf1
|
APN |
19 |
36,926,508 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03353:Btaf1
|
APN |
19 |
36,969,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
freudenberg
|
UTSW |
19 |
36,965,573 (GRCm39) |
critical splice donor site |
probably null |
|
|
Galanos
|
UTSW |
19 |
36,926,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Btaf1
|
UTSW |
19 |
36,987,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0013:Btaf1
|
UTSW |
19 |
36,935,773 (GRCm39) |
missense |
probably benign |
|
|
R0048:Btaf1
|
UTSW |
19 |
36,980,924 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0117:Btaf1
|
UTSW |
19 |
36,947,368 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0207:Btaf1
|
UTSW |
19 |
36,987,048 (GRCm39) |
nonsense |
probably null |
|
|
R0310:Btaf1
|
UTSW |
19 |
36,981,934 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0377:Btaf1
|
UTSW |
19 |
36,966,402 (GRCm39) |
missense |
probably benign |
|
|
R0419:Btaf1
|
UTSW |
19 |
36,922,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0440:Btaf1
|
UTSW |
19 |
36,964,053 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0532:Btaf1
|
UTSW |
19 |
36,928,586 (GRCm39) |
splice site |
probably benign |
|
|
R0612:Btaf1
|
UTSW |
19 |
36,946,537 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0731:Btaf1
|
UTSW |
19 |
36,974,895 (GRCm39) |
splice site |
probably null |
|
|
R0780:Btaf1
|
UTSW |
19 |
36,966,322 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0919:Btaf1
|
UTSW |
19 |
36,968,143 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1104:Btaf1
|
UTSW |
19 |
36,982,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1263:Btaf1
|
UTSW |
19 |
36,933,924 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1325:Btaf1
|
UTSW |
19 |
36,946,562 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1447:Btaf1
|
UTSW |
19 |
36,969,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1554:Btaf1
|
UTSW |
19 |
36,973,998 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1649:Btaf1
|
UTSW |
19 |
36,959,122 (GRCm39) |
missense |
probably benign |
|
|
R1715:Btaf1
|
UTSW |
19 |
36,946,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1733:Btaf1
|
UTSW |
19 |
36,972,362 (GRCm39) |
missense |
probably benign |
|
|
R1764:Btaf1
|
UTSW |
19 |
36,928,518 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1911:Btaf1
|
UTSW |
19 |
36,964,030 (GRCm39) |
missense |
probably benign |
|
|
R1933:Btaf1
|
UTSW |
19 |
36,950,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2080:Btaf1
|
UTSW |
19 |
36,928,548 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2483:Btaf1
|
UTSW |
19 |
36,958,486 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2510:Btaf1
|
UTSW |
19 |
36,979,845 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3623:Btaf1
|
UTSW |
19 |
36,958,486 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3624:Btaf1
|
UTSW |
19 |
36,958,486 (GRCm39) |
missense |
probably benign |
0.02 |
|
R3801:Btaf1
|
UTSW |
19 |
36,966,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3801:Btaf1
|
UTSW |
19 |
36,963,948 (GRCm39) |
missense |
probably benign |
|
|
R3802:Btaf1
|
UTSW |
19 |
36,966,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3802:Btaf1
|
UTSW |
19 |
36,963,948 (GRCm39) |
missense |
probably benign |
|
|
R3803:Btaf1
|
UTSW |
19 |
36,966,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3803:Btaf1
|
UTSW |
19 |
36,963,948 (GRCm39) |
missense |
probably benign |
|
|
R4077:Btaf1
|
UTSW |
19 |
36,963,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4079:Btaf1
|
UTSW |
19 |
36,963,879 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4133:Btaf1
|
UTSW |
19 |
36,939,138 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4673:Btaf1
|
UTSW |
19 |
36,955,772 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4731:Btaf1
|
UTSW |
19 |
36,958,478 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4796:Btaf1
|
UTSW |
19 |
36,933,828 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R4824:Btaf1
|
UTSW |
19 |
36,958,448 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4835:Btaf1
|
UTSW |
19 |
36,979,858 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4837:Btaf1
|
UTSW |
19 |
36,944,185 (GRCm39) |
missense |
probably benign |
|
|
R4925:Btaf1
|
UTSW |
19 |
36,988,733 (GRCm39) |
missense |
probably benign |
|
|
R4968:Btaf1
|
UTSW |
19 |
36,947,351 (GRCm39) |
missense |
probably null |
0.71 |
|
R4976:Btaf1
|
UTSW |
19 |
36,963,979 (GRCm39) |
missense |
probably benign |
|
|
R5001:Btaf1
|
UTSW |
19 |
36,964,052 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5037:Btaf1
|
UTSW |
19 |
36,980,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Btaf1
|
UTSW |
19 |
36,968,162 (GRCm39) |
missense |
probably benign |
|
|
R5211:Btaf1
|
UTSW |
19 |
36,973,962 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5422:Btaf1
|
UTSW |
19 |
36,928,507 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5429:Btaf1
|
UTSW |
19 |
36,972,257 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5530:Btaf1
|
UTSW |
19 |
36,968,175 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5582:Btaf1
|
UTSW |
19 |
36,965,573 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5654:Btaf1
|
UTSW |
19 |
36,961,015 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5744:Btaf1
|
UTSW |
19 |
36,981,890 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6082:Btaf1
|
UTSW |
19 |
36,960,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6243:Btaf1
|
UTSW |
19 |
36,958,520 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6291:Btaf1
|
UTSW |
19 |
36,950,408 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6502:Btaf1
|
UTSW |
19 |
36,961,017 (GRCm39) |
missense |
probably benign |
|
|
R7034:Btaf1
|
UTSW |
19 |
36,981,869 (GRCm39) |
missense |
probably benign |
|
|
R7036:Btaf1
|
UTSW |
19 |
36,981,869 (GRCm39) |
missense |
probably benign |
|
|
R7085:Btaf1
|
UTSW |
19 |
36,950,318 (GRCm39) |
missense |
probably benign |
|
|
R7097:Btaf1
|
UTSW |
19 |
36,926,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Btaf1
|
UTSW |
19 |
36,922,714 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7386:Btaf1
|
UTSW |
19 |
36,935,782 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7402:Btaf1
|
UTSW |
19 |
36,980,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7452:Btaf1
|
UTSW |
19 |
36,946,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7493:Btaf1
|
UTSW |
19 |
36,987,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7513:Btaf1
|
UTSW |
19 |
36,955,803 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7888:Btaf1
|
UTSW |
19 |
36,943,036 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7944:Btaf1
|
UTSW |
19 |
36,926,565 (GRCm39) |
missense |
probably benign |
|
|
R8062:Btaf1
|
UTSW |
19 |
36,969,865 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8559:Btaf1
|
UTSW |
19 |
36,964,273 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8793:Btaf1
|
UTSW |
19 |
36,958,429 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8855:Btaf1
|
UTSW |
19 |
36,935,901 (GRCm39) |
missense |
probably benign |
|
|
R8866:Btaf1
|
UTSW |
19 |
36,935,901 (GRCm39) |
missense |
probably benign |
|
|
R9016:Btaf1
|
UTSW |
19 |
36,971,705 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9028:Btaf1
|
UTSW |
19 |
36,946,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9109:Btaf1
|
UTSW |
19 |
36,964,114 (GRCm39) |
missense |
probably benign |
|
|
R9172:Btaf1
|
UTSW |
19 |
36,977,630 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9298:Btaf1
|
UTSW |
19 |
36,964,114 (GRCm39) |
missense |
probably benign |
|
|
R9717:Btaf1
|
UTSW |
19 |
36,922,646 (GRCm39) |
missense |
probably benign |
0.28 |
|
W0251:Btaf1
|
UTSW |
19 |
36,980,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Btaf1
|
UTSW |
19 |
36,926,496 (GRCm39) |
nonsense |
probably null |
|
|
Z1088:Btaf1
|
UTSW |
19 |
36,964,018 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCGGTGCTCTTAACCACTG -3'
(R):5'- GCTGAACACAGAAATACCACGTTTC -3'
Sequencing Primer
(F):5'- TGAACCATCTCTCCAGGCG -3'
(R):5'- AGAAATACCACGTTTCTCTACCC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation