Incidental Mutation 'R1891:Nbas'
| ID |
211522 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nbas
|
| Ensembl Gene |
ENSMUSG00000020576 |
| Gene Name |
neuroblastoma amplified sequence |
| Synonyms |
4933425L03Rik |
| MMRRC Submission |
039911-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1891 (G1)
|
| Quality Score |
182 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
13319134-13633812 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 13440973 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Threonine
at position 1101
(M1101T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000036082
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000042953]
|
| AlphaFold |
E9Q411 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000042953
AA Change: M1101T
PolyPhen 2
Score 0.922 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000036082
Gene: ENSMUSG00000020576
AA Change: M1101T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nbas_N
|
89 |
370 |
4.7e-171 |
PFAM |
|
low complexity region
|
463 |
475 |
N/A |
INTRINSIC |
|
low complexity region
|
653 |
667 |
N/A |
INTRINSIC |
|
Pfam:Sec39
|
725 |
1375 |
3.8e-34 |
PFAM |
|
low complexity region
|
1392 |
1404 |
N/A |
INTRINSIC |
|
low complexity region
|
1549 |
1566 |
N/A |
INTRINSIC |
|
low complexity region
|
2226 |
2252 |
N/A |
INTRINSIC |
|
low complexity region
|
2275 |
2285 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012]
|
| Allele List at MGI |
All alleles(10) : Targeted, other(2) Gene trapped(8)
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca7 |
T |
C |
10: 79,840,874 (GRCm39) |
I921T |
possibly damaging |
Het |
| Abca8a |
T |
C |
11: 109,982,433 (GRCm39) |
K3R |
probably benign |
Het |
| Adgrl3 |
A |
T |
5: 81,659,891 (GRCm39) |
D152V |
probably damaging |
Het |
| Akap6 |
A |
T |
12: 53,188,958 (GRCm39) |
D2124V |
possibly damaging |
Het |
| Akt1 |
A |
G |
12: 112,626,009 (GRCm39) |
F88L |
probably damaging |
Het |
| Ankrd24 |
T |
C |
10: 81,479,342 (GRCm39) |
|
probably benign |
Het |
| Arid4b |
T |
A |
13: 14,310,821 (GRCm39) |
N141K |
possibly damaging |
Het |
| Cacna1c |
C |
A |
6: 118,753,480 (GRCm39) |
D219Y |
probably damaging |
Het |
| Ccdc113 |
A |
G |
8: 96,267,544 (GRCm39) |
K170E |
probably damaging |
Het |
| Ceacam9 |
A |
G |
7: 16,457,880 (GRCm39) |
E136G |
probably damaging |
Het |
| Cfap43 |
A |
G |
19: 47,802,380 (GRCm39) |
L333P |
probably damaging |
Het |
| Chl1 |
A |
G |
6: 103,691,544 (GRCm39) |
D1062G |
possibly damaging |
Het |
| Cimip4 |
T |
A |
15: 78,262,952 (GRCm39) |
D234V |
probably damaging |
Het |
| Ckb |
TCCACCACCA |
TCCACCA |
12: 111,636,079 (GRCm39) |
|
probably benign |
Het |
| Clpp |
T |
A |
17: 57,298,307 (GRCm39) |
V91E |
probably damaging |
Het |
| Cndp1 |
A |
T |
18: 84,637,758 (GRCm39) |
H325Q |
probably null |
Het |
| Cngb3 |
A |
G |
4: 19,366,446 (GRCm39) |
N169S |
probably benign |
Het |
| Cog6 |
A |
C |
3: 52,890,601 (GRCm39) |
I613R |
probably benign |
Het |
| Creb3l1 |
A |
G |
2: 91,817,385 (GRCm39) |
L376P |
probably damaging |
Het |
| Cry2 |
A |
T |
2: 92,243,985 (GRCm39) |
V396D |
possibly damaging |
Het |
| Cxxc5 |
A |
G |
18: 35,992,318 (GRCm39) |
M240V |
possibly damaging |
Het |
| Defa28 |
G |
A |
8: 22,073,801 (GRCm39) |
C68Y |
probably damaging |
Het |
| Ecd |
A |
G |
14: 20,388,227 (GRCm39) |
I187T |
probably damaging |
Het |
| Erg28 |
A |
G |
12: 85,862,962 (GRCm39) |
S117P |
probably benign |
Het |
| Ergic2 |
A |
T |
6: 148,084,577 (GRCm39) |
C319S |
probably damaging |
Het |
| Ess2 |
C |
T |
16: 17,725,644 (GRCm39) |
W183* |
probably null |
Het |
| Evc2 |
A |
C |
5: 37,549,423 (GRCm39) |
D773A |
probably damaging |
Het |
| Fam151b |
T |
A |
13: 92,586,678 (GRCm39) |
T252S |
probably benign |
Het |
| Fbxo28 |
A |
T |
1: 182,145,389 (GRCm39) |
M233K |
probably benign |
Het |
| Fbxw26 |
T |
G |
9: 109,551,232 (GRCm39) |
D355A |
probably benign |
Het |
| Gm4884 |
G |
C |
7: 40,692,539 (GRCm39) |
E169D |
possibly damaging |
Het |
| Hk2 |
C |
T |
6: 82,726,264 (GRCm39) |
R94Q |
probably benign |
Het |
| Hps4 |
G |
A |
5: 112,517,422 (GRCm39) |
|
probably null |
Het |
| Hspg2 |
T |
A |
4: 137,292,801 (GRCm39) |
D4126E |
probably damaging |
Het |
| Kif13a |
T |
C |
13: 47,082,695 (GRCm39) |
E48G |
possibly damaging |
Het |
| Krt31 |
T |
A |
11: 99,938,634 (GRCm39) |
N320Y |
probably damaging |
Het |
| Lca5 |
T |
C |
9: 83,277,661 (GRCm39) |
Y561C |
probably damaging |
Het |
| Lrrk1 |
G |
A |
7: 65,929,048 (GRCm39) |
L1195F |
probably damaging |
Het |
| Ly6g6d |
A |
C |
17: 35,293,269 (GRCm39) |
Y25* |
probably null |
Het |
| Map3k13 |
T |
G |
16: 21,729,836 (GRCm39) |
M489R |
probably damaging |
Het |
| Mcm6 |
C |
T |
1: 128,263,547 (GRCm39) |
R658H |
probably damaging |
Het |
| Mecp2 |
C |
T |
X: 73,080,781 (GRCm39) |
A79T |
probably damaging |
Het |
| Mitf |
A |
G |
6: 97,918,237 (GRCm39) |
T94A |
probably benign |
Het |
| Mpo |
T |
A |
11: 87,692,106 (GRCm39) |
L513* |
probably null |
Het |
| Mst1r |
T |
A |
9: 107,790,661 (GRCm39) |
N722K |
probably damaging |
Het |
| Mthfd1l |
T |
A |
10: 3,982,284 (GRCm39) |
L497* |
probably null |
Het |
| Mtus1 |
C |
T |
8: 41,537,362 (GRCm39) |
S118N |
probably damaging |
Het |
| Mybbp1a |
C |
T |
11: 72,336,863 (GRCm39) |
T565I |
probably benign |
Het |
| Naip2 |
C |
T |
13: 100,291,395 (GRCm39) |
R1181K |
probably benign |
Het |
| Odad3 |
G |
T |
9: 21,906,677 (GRCm39) |
|
probably null |
Het |
| Or2y1b |
T |
C |
11: 49,208,684 (GRCm39) |
F104L |
probably benign |
Het |
| Or4f60 |
A |
T |
2: 111,902,739 (GRCm39) |
L63Q |
probably damaging |
Het |
| Or52l1 |
A |
T |
7: 104,829,754 (GRCm39) |
Y270* |
probably null |
Het |
| Or5ae1 |
T |
A |
7: 84,565,461 (GRCm39) |
V158D |
possibly damaging |
Het |
| Or6c33 |
T |
C |
10: 129,853,439 (GRCm39) |
S70P |
probably damaging |
Het |
| Or7a40 |
T |
A |
16: 16,491,441 (GRCm39) |
I135F |
probably damaging |
Het |
| Or7g20 |
T |
C |
9: 18,947,274 (GRCm39) |
L285S |
probably damaging |
Het |
| Or8b12b |
T |
A |
9: 37,684,163 (GRCm39) |
D69E |
possibly damaging |
Het |
| Oxct2b |
A |
G |
4: 123,010,938 (GRCm39) |
D286G |
probably benign |
Het |
| Pax5 |
A |
T |
4: 44,691,859 (GRCm39) |
V129E |
probably damaging |
Het |
| Pax7 |
G |
A |
4: 139,511,937 (GRCm39) |
R215C |
probably damaging |
Het |
| Pcdh7 |
A |
T |
5: 57,878,217 (GRCm39) |
I591F |
probably damaging |
Het |
| Pcdhb22 |
T |
C |
18: 37,652,357 (GRCm39) |
V275A |
probably damaging |
Het |
| Pkp3 |
C |
T |
7: 140,663,969 (GRCm39) |
|
probably null |
Het |
| Plekhb1 |
A |
G |
7: 100,304,599 (GRCm39) |
L35P |
probably damaging |
Het |
| Pole |
T |
A |
5: 110,480,408 (GRCm39) |
F1993Y |
probably damaging |
Het |
| Pramel28 |
A |
T |
4: 143,693,235 (GRCm39) |
V81E |
probably damaging |
Het |
| Prdx1 |
T |
C |
4: 116,556,451 (GRCm39) |
*200R |
probably null |
Het |
| Prkdc |
C |
A |
16: 15,543,300 (GRCm39) |
T1777N |
probably benign |
Het |
| Prss59 |
A |
T |
6: 40,902,967 (GRCm39) |
M135K |
possibly damaging |
Het |
| Ptpn14 |
G |
A |
1: 189,530,850 (GRCm39) |
V106M |
probably damaging |
Het |
| Ptpn23 |
T |
C |
9: 110,222,868 (GRCm39) |
E63G |
possibly damaging |
Het |
| Qser1 |
A |
C |
2: 104,620,444 (GRCm39) |
S123A |
probably benign |
Het |
| Rbm11 |
A |
G |
16: 75,397,675 (GRCm39) |
N202D |
possibly damaging |
Het |
| Robo3 |
T |
A |
9: 37,339,351 (GRCm39) |
Y212F |
probably damaging |
Het |
| Sde2 |
G |
A |
1: 180,687,573 (GRCm39) |
S153N |
probably benign |
Het |
| Serpinb1c |
T |
A |
13: 33,068,235 (GRCm39) |
D179V |
probably benign |
Het |
| Skint6 |
T |
C |
4: 112,703,893 (GRCm39) |
D994G |
possibly damaging |
Het |
| Sorbs1 |
A |
G |
19: 40,381,904 (GRCm39) |
S46P |
probably damaging |
Het |
| St8sia4 |
T |
C |
1: 95,519,433 (GRCm39) |
T352A |
possibly damaging |
Het |
| Stab1 |
C |
A |
14: 30,863,287 (GRCm39) |
R2133L |
probably benign |
Het |
| Stk11ip |
T |
C |
1: 75,509,060 (GRCm39) |
C730R |
probably benign |
Het |
| Tedc2 |
C |
A |
17: 24,435,292 (GRCm39) |
E366* |
probably null |
Het |
| Tedc2 |
T |
A |
17: 24,435,291 (GRCm39) |
E366V |
probably damaging |
Het |
| Tle4 |
A |
T |
19: 14,522,150 (GRCm39) |
|
probably null |
Het |
| Tmem200a |
T |
A |
10: 25,869,970 (GRCm39) |
N100Y |
probably damaging |
Het |
| Tnnt2 |
A |
T |
1: 135,768,597 (GRCm39) |
|
probably null |
Het |
| Ttn |
T |
A |
2: 76,706,302 (GRCm39) |
|
probably benign |
Het |
| Ubac1 |
A |
G |
2: 25,904,974 (GRCm39) |
V88A |
probably benign |
Het |
| Urgcp |
T |
C |
11: 5,666,910 (GRCm39) |
E476G |
probably benign |
Het |
| Vmn1r201 |
G |
A |
13: 22,659,425 (GRCm39) |
R213H |
probably benign |
Het |
| Vmn2r84 |
C |
T |
10: 130,221,938 (GRCm39) |
V761M |
possibly damaging |
Het |
| Vwde |
A |
T |
6: 13,187,454 (GRCm39) |
Y678N |
probably damaging |
Het |
| Wnk2 |
C |
A |
13: 49,206,200 (GRCm39) |
E1865* |
probably null |
Het |
| Zc3h3 |
A |
C |
15: 75,628,780 (GRCm39) |
M838R |
possibly damaging |
Het |
| Zfp959 |
T |
A |
17: 56,204,604 (GRCm39) |
C211S |
probably damaging |
Het |
|
| Other mutations in Nbas |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00486:Nbas
|
APN |
12 |
13,503,076 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL00712:Nbas
|
APN |
12 |
13,412,626 (GRCm39) |
splice site |
probably benign |
|
|
IGL00808:Nbas
|
APN |
12 |
13,616,121 (GRCm39) |
splice site |
probably benign |
|
|
IGL00915:Nbas
|
APN |
12 |
13,424,753 (GRCm39) |
nonsense |
probably null |
|
|
IGL00923:Nbas
|
APN |
12 |
13,386,285 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01152:Nbas
|
APN |
12 |
13,410,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Nbas
|
APN |
12 |
13,533,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01672:Nbas
|
APN |
12 |
13,429,650 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL01799:Nbas
|
APN |
12 |
13,374,401 (GRCm39) |
splice site |
probably benign |
|
|
IGL01812:Nbas
|
APN |
12 |
13,503,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01934:Nbas
|
APN |
12 |
13,339,880 (GRCm39) |
splice site |
probably benign |
|
|
IGL02093:Nbas
|
APN |
12 |
13,610,963 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02115:Nbas
|
APN |
12 |
13,367,693 (GRCm39) |
splice site |
probably benign |
|
|
IGL02175:Nbas
|
APN |
12 |
13,616,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02268:Nbas
|
APN |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02483:Nbas
|
APN |
12 |
13,374,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02539:Nbas
|
APN |
12 |
13,322,704 (GRCm39) |
splice site |
probably benign |
|
|
IGL02557:Nbas
|
APN |
12 |
13,411,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Nbas
|
APN |
12 |
13,360,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Nbas
|
APN |
12 |
13,412,542 (GRCm39) |
missense |
probably benign |
|
|
IGL03131:Nbas
|
APN |
12 |
13,329,417 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL03214:Nbas
|
APN |
12 |
13,381,111 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Nbas
|
APN |
12 |
13,374,349 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03368:Nbas
|
APN |
12 |
13,378,452 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03372:Nbas
|
APN |
12 |
13,584,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03391:Nbas
|
APN |
12 |
13,533,750 (GRCm39) |
missense |
probably benign |
0.28 |
|
medvedev
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
oligarchs
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
putin
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):Nbas
|
UTSW |
12 |
13,338,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0057:Nbas
|
UTSW |
12 |
13,440,958 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0076:Nbas
|
UTSW |
12 |
13,374,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0153:Nbas
|
UTSW |
12 |
13,323,877 (GRCm39) |
splice site |
probably benign |
|
|
R0371:Nbas
|
UTSW |
12 |
13,381,096 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0449:Nbas
|
UTSW |
12 |
13,569,109 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0791:Nbas
|
UTSW |
12 |
13,532,634 (GRCm39) |
missense |
probably benign |
0.28 |
|
R0931:Nbas
|
UTSW |
12 |
13,381,115 (GRCm39) |
splice site |
probably benign |
|
|
R1236:Nbas
|
UTSW |
12 |
13,319,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1371:Nbas
|
UTSW |
12 |
13,532,379 (GRCm39) |
splice site |
probably benign |
|
|
R1567:Nbas
|
UTSW |
12 |
13,335,279 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1587:Nbas
|
UTSW |
12 |
13,608,686 (GRCm39) |
missense |
probably benign |
|
|
R1719:Nbas
|
UTSW |
12 |
13,610,978 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1747:Nbas
|
UTSW |
12 |
13,385,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1777:Nbas
|
UTSW |
12 |
13,563,563 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1848:Nbas
|
UTSW |
12 |
13,463,598 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1856:Nbas
|
UTSW |
12 |
13,524,230 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1911:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R1912:Nbas
|
UTSW |
12 |
13,616,145 (GRCm39) |
missense |
probably benign |
|
|
R2006:Nbas
|
UTSW |
12 |
13,464,742 (GRCm39) |
splice site |
probably null |
|
|
R2054:Nbas
|
UTSW |
12 |
13,524,207 (GRCm39) |
missense |
probably benign |
0.36 |
|
R2065:Nbas
|
UTSW |
12 |
13,616,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2089:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2091:Nbas
|
UTSW |
12 |
13,411,046 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2156:Nbas
|
UTSW |
12 |
13,491,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2164:Nbas
|
UTSW |
12 |
13,380,647 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R2339:Nbas
|
UTSW |
12 |
13,412,593 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2398:Nbas
|
UTSW |
12 |
13,482,946 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3806:Nbas
|
UTSW |
12 |
13,532,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3855:Nbas
|
UTSW |
12 |
13,329,415 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4019:Nbas
|
UTSW |
12 |
13,532,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4083:Nbas
|
UTSW |
12 |
13,524,192 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4201:Nbas
|
UTSW |
12 |
13,424,827 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4231:Nbas
|
UTSW |
12 |
13,443,344 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4552:Nbas
|
UTSW |
12 |
13,385,938 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4560:Nbas
|
UTSW |
12 |
13,633,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4728:Nbas
|
UTSW |
12 |
13,338,740 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4752:Nbas
|
UTSW |
12 |
13,532,538 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4832:Nbas
|
UTSW |
12 |
13,533,740 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4874:Nbas
|
UTSW |
12 |
13,371,756 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4988:Nbas
|
UTSW |
12 |
13,458,266 (GRCm39) |
missense |
probably benign |
0.45 |
|
R5020:Nbas
|
UTSW |
12 |
13,424,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5079:Nbas
|
UTSW |
12 |
13,424,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5129:Nbas
|
UTSW |
12 |
13,440,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5239:Nbas
|
UTSW |
12 |
13,491,519 (GRCm39) |
missense |
probably benign |
0.31 |
|
R5299:Nbas
|
UTSW |
12 |
13,491,926 (GRCm39) |
nonsense |
probably null |
|
|
R5351:Nbas
|
UTSW |
12 |
13,610,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5389:Nbas
|
UTSW |
12 |
13,584,578 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5436:Nbas
|
UTSW |
12 |
13,424,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5654:Nbas
|
UTSW |
12 |
13,633,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Nbas
|
UTSW |
12 |
13,386,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5842:Nbas
|
UTSW |
12 |
13,319,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5959:Nbas
|
UTSW |
12 |
13,338,802 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5982:Nbas
|
UTSW |
12 |
13,443,431 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6238:Nbas
|
UTSW |
12 |
13,532,596 (GRCm39) |
missense |
probably benign |
|
|
R6270:Nbas
|
UTSW |
12 |
13,374,294 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6363:Nbas
|
UTSW |
12 |
13,532,577 (GRCm39) |
missense |
probably benign |
|
|
R6424:Nbas
|
UTSW |
12 |
13,465,734 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6458:Nbas
|
UTSW |
12 |
13,338,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Nbas
|
UTSW |
12 |
13,455,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6654:Nbas
|
UTSW |
12 |
13,533,875 (GRCm39) |
nonsense |
probably null |
|
|
R7085:Nbas
|
UTSW |
12 |
13,335,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Nbas
|
UTSW |
12 |
13,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7197:Nbas
|
UTSW |
12 |
13,570,751 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R7378:Nbas
|
UTSW |
12 |
13,324,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7393:Nbas
|
UTSW |
12 |
13,443,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7425:Nbas
|
UTSW |
12 |
13,519,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7446:Nbas
|
UTSW |
12 |
13,443,499 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7481:Nbas
|
UTSW |
12 |
13,406,960 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7535:Nbas
|
UTSW |
12 |
13,329,390 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7626:Nbas
|
UTSW |
12 |
13,608,661 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7678:Nbas
|
UTSW |
12 |
13,465,662 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7912:Nbas
|
UTSW |
12 |
13,455,458 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7964:Nbas
|
UTSW |
12 |
13,406,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8193:Nbas
|
UTSW |
12 |
13,483,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8325:Nbas
|
UTSW |
12 |
13,338,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8405:Nbas
|
UTSW |
12 |
13,329,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8437:Nbas
|
UTSW |
12 |
13,616,251 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8559:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8684:Nbas
|
UTSW |
12 |
13,386,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8826:Nbas
|
UTSW |
12 |
13,402,875 (GRCm39) |
splice site |
probably benign |
|
|
R8921:Nbas
|
UTSW |
12 |
13,463,590 (GRCm39) |
missense |
probably benign |
|
|
R8956:Nbas
|
UTSW |
12 |
13,482,923 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R9083:Nbas
|
UTSW |
12 |
13,385,856 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R9172:Nbas
|
UTSW |
12 |
13,424,751 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9430:Nbas
|
UTSW |
12 |
13,371,654 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9627:Nbas
|
UTSW |
12 |
13,350,203 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R9649:Nbas
|
UTSW |
12 |
13,633,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF013:Nbas
|
UTSW |
12 |
13,329,409 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
T0722:Nbas
|
UTSW |
12 |
13,402,809 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Nbas
|
UTSW |
12 |
13,533,877 (GRCm39) |
missense |
probably benign |
0.06 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGAATTTGAAACTCTTGCCTGTC -3'
(R):5'- GAAGGCAGCTGTTAATCACACTG -3'
Sequencing Primer
(F):5'- CCTCAACATAGGAATTCTGTTTACC -3'
(R):5'- CAGCTGTTAATCACACTGCATAC -3'
|
| Posted On |
2014-06-30 |
Incidental Mutation