Mutagenetix > Incidental Mutation

Incidental Mutation 'R1893:Dnah10'

211690

Institutional Source

Beutler Lab

Gene Symbol

Dnah10

Ensembl Gene

ENSMUSG00000038011

Gene Name

dynein, axonemal, heavy chain 10

Synonyms

Dnahc10

MMRRC Submission

039913-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1893 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

124802149-124911372 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 124831381 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 803 (V803A)

Ref Sequence

ENSEMBL: ENSMUSP00000114593 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000058440] [ENSMUST00000141137]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000058440
AA Change: V860A

PolyPhen 2 Score 0.059 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000062995
Gene: ENSMUSG00000038011
AA Change: V860A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	305	878	9.1e-154	PFAM
coiled coil region	1191	1218	N/A	INTRINSIC
coiled coil region	1337	1360	N/A	INTRINSIC
Pfam:DHC_N2	1374	1782	1.7e-142	PFAM
AAA	1946	2082	2.51e-1	SMART
AAA	2225	2373	6.91e-1	SMART
low complexity region	2444	2464	N/A	INTRINSIC
AAA	2567	2720	2.29e-2	SMART
Pfam:AAA_8	2886	3153	9.8e-87	PFAM
Pfam:MT	3165	3502	9.1e-53	PFAM
Pfam:AAA_9	3522	3747	2.3e-90	PFAM
Pfam:Dynein_heavy	3884	4588	7.6e-240	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000141137
AA Change: V803A

PolyPhen 2 Score 0.129 (Sensitivity: 0.93; Specificity: 0.86)

SMART Domains

Protein: ENSMUSP00000114593
Gene: ENSMUSG00000038011
AA Change: V803A

Domain	Start	End	E-Value	Type
low complexity region	63	72	N/A	INTRINSIC
low complexity region	80	86	N/A	INTRINSIC
coiled coil region	260	282	N/A	INTRINSIC
Pfam:DHC_N1	304	607	4.3e-57	PFAM
Pfam:DHC_N1	598	823	1.2e-39	PFAM
coiled coil region	1134	1161	N/A	INTRINSIC
coiled coil region	1280	1303	N/A	INTRINSIC
Pfam:DHC_N2	1315	1727	7.3e-135	PFAM
AAA	1889	2025	4e-3	SMART
AAA	2168	2316	1.1e-2	SMART
low complexity region	2387	2407	N/A	INTRINSIC
AAA	2510	2663	3.6e-4	SMART
Pfam:AAA_8	2829	3096	2.5e-83	PFAM
Pfam:MT	3108	3445	1.2e-50	PFAM
Pfam:AAA_9	3461	3691	6.7e-59	PFAM
Pfam:Dynein_heavy	3821	4532	1.9e-231	PFAM

Meta Mutation Damage Score

0.0945

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.4%
20x: 93.0%

Validation Efficiency

99% (99/100)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH10 is an inner arm dynein heavy chain (Maiti et al., 2000 [PubMed 11175280]).[supplied by OMIM, Mar 2008]

Allele List at MGI

All alleles(2) : Gene trapped(2)

Other mutations in this stock

Total: 93 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2210408I21Rik	T	C	13: 77,415,928 (GRCm39)	Y674H	possibly damaging	Het
Aars2	G	A	17: 45,825,725 (GRCm39)	R347Q	probably benign	Het
Abca15	A	T	7: 119,939,776 (GRCm39)	M293L	possibly damaging	Het
Abcb7	A	T	X: 103,386,142 (GRCm39)	H97Q	probably damaging	Het
Aldh1l2	G	T	10: 83,328,400 (GRCm39)	N772K	probably damaging	Het
Ascc2	T	A	11: 4,622,305 (GRCm39)	L457Q	probably benign	Het
Aspm	T	A	1: 139,407,605 (GRCm39)	I2164N	probably damaging	Het
Cabs1	A	G	5: 88,127,894 (GRCm39)	T182A	probably benign	Het
Carmil1	T	C	13: 24,208,446 (GRCm39)	E833G	possibly damaging	Het
Ccdc102a	G	A	8: 95,640,171 (GRCm39)	T41M	probably damaging	Het
Cimap1c	A	G	9: 56,756,498 (GRCm39)	Y173H	probably benign	Het
Clec2h	T	C	6: 128,647,795 (GRCm39)	V48A	probably benign	Het
Cpb2	G	A	14: 75,493,403 (GRCm39)	V27I	probably benign	Het
Cr2	T	C	1: 194,837,495 (GRCm39)	H1201R	probably benign	Het
Cyp2d9	T	C	15: 82,336,807 (GRCm39)	V52A	probably damaging	Het
Cyp4a12a	C	A	4: 115,183,864 (GRCm39)	N223K	probably benign	Het
Cyp7b1	G	A	3: 18,150,731 (GRCm39)	S336L	possibly damaging	Het
Dnah17	T	A	11: 117,957,794 (GRCm39)	T2745S	probably benign	Het
Ep300	T	A	15: 81,515,847 (GRCm39)		probably benign	Het
Epha3	A	G	16: 63,388,762 (GRCm39)	S829P	probably damaging	Het
Fads3	C	A	19: 10,033,868 (GRCm39)	H418N	probably benign	Het
Fat1	T	C	8: 45,476,893 (GRCm39)	S1980P	probably damaging	Het
Fgf20	T	C	8: 40,732,844 (GRCm39)	E198G	possibly damaging	Het
Fgl2	G	A	5: 21,580,669 (GRCm39)	R337H	probably benign	Het
Gbp2	G	T	3: 142,335,933 (GRCm39)		probably benign	Het
Gja10	G	A	4: 32,601,541 (GRCm39)	S281L	probably benign	Het
Gm5422	G	A	10: 31,125,609 (GRCm39)		noncoding transcript	Het
Gmpr	T	A	13: 45,674,423 (GRCm39)	D129E	possibly damaging	Het
Gtf3c4	C	T	2: 28,724,374 (GRCm39)	V453I	possibly damaging	Het
Heatr6	T	C	11: 83,648,140 (GRCm39)	V111A	probably benign	Het
Hipk3	G	A	2: 104,263,601 (GRCm39)	R905W	probably damaging	Het
Hpn	T	A	7: 30,798,773 (GRCm39)	D103V	probably damaging	Het
Ipcef1	G	A	10: 6,850,680 (GRCm39)	R304W	probably damaging	Het
Iqcb1	A	G	16: 36,652,245 (GRCm39)	D52G	probably damaging	Het
Klhdc7b	C	T	15: 89,271,898 (GRCm39)		probably null	Het
Klhl1	A	T	14: 96,477,642 (GRCm39)		probably null	Het
Lrrn1	A	T	6: 107,545,083 (GRCm39)	I294F	possibly damaging	Het
Map3k1	A	T	13: 111,904,567 (GRCm39)	F406I	possibly damaging	Het
Map4k4	T	A	1: 40,040,717 (GRCm39)	V579E	probably benign	Het
Mapre2	A	G	18: 23,986,774 (GRCm39)	K62R	probably damaging	Het
Mdga1	A	T	17: 30,068,200 (GRCm39)	Y305N	probably damaging	Het
Mgl2	T	A	11: 70,024,993 (GRCm39)		probably null	Het
Mnx1	C	T	5: 29,682,828 (GRCm39)	G149D	unknown	Het
Mtbp	T	A	15: 55,421,064 (GRCm39)	S17T	probably benign	Het
Neu3	T	C	7: 99,472,627 (GRCm39)	T37A	possibly damaging	Het
Nr1i3	T	C	1: 171,044,792 (GRCm39)		probably null	Het
Or10al2	A	T	17: 37,983,747 (GRCm39)	K278*	probably null	Het
Or10g6	A	T	9: 39,934,270 (GRCm39)	I194F	possibly damaging	Het
Or6ae1	T	C	7: 139,742,734 (GRCm39)	N43S	probably damaging	Het
Or9s18	T	A	13: 65,300,806 (GRCm39)	M256K	possibly damaging	Het
Osr2	A	G	15: 35,300,608 (GRCm39)	T55A	possibly damaging	Het
Palld	A	G	8: 61,969,655 (GRCm39)	V981A	probably damaging	Het
Pbx1	A	T	1: 168,030,979 (GRCm39)	M213K	possibly damaging	Het
Pcdhb12	C	A	18: 37,570,136 (GRCm39)	H427Q	probably benign	Het
Perm1	C	T	4: 156,302,340 (GRCm39)	R295C	probably benign	Het
Phaf1	G	T	8: 105,973,133 (GRCm39)	V248F	probably damaging	Het
Polm	T	C	11: 5,785,574 (GRCm39)	T162A	possibly damaging	Het
Prox1	A	G	1: 189,892,715 (GRCm39)		probably benign	Het
Ptpn7	A	T	1: 135,062,641 (GRCm39)	T127S	probably benign	Het
Pxk	C	T	14: 8,151,507 (GRCm38)	R441*	probably null	Het
Rab21	T	C	10: 115,126,805 (GRCm39)	T181A	probably benign	Het
Rab38	A	T	7: 88,139,924 (GRCm39)	T198S	probably benign	Het
Rnase4	C	G	14: 51,342,395 (GRCm39)	Q40E	possibly damaging	Het
Rnf213	T	A	11: 119,307,274 (GRCm39)	W645R	probably damaging	Het
Rnf8	A	G	17: 29,840,524 (GRCm39)	I51M	probably damaging	Het
Sbpl	T	A	17: 24,172,241 (GRCm39)	D226V	unknown	Het
Sdf4	T	G	4: 156,085,205 (GRCm39)	I180S	probably benign	Het
Simc1	A	G	13: 54,687,528 (GRCm39)	K99R	probably damaging	Het
Slc2a4	T	C	11: 69,837,398 (GRCm39)	Q49R	probably damaging	Het
Slco1a4	T	C	6: 141,780,342 (GRCm39)		probably null	Het
Slco5a1	C	A	1: 12,964,696 (GRCm39)	C527F	probably damaging	Het
Sox6	T	A	7: 115,143,803 (GRCm39)	N405I	probably benign	Het
Sphkap	G	A	1: 83,256,687 (GRCm39)	P354L	probably benign	Het
Spi1	A	G	2: 90,944,702 (GRCm39)	D149G	probably benign	Het
Sptan1	T	A	2: 29,910,472 (GRCm39)	D1812E	probably damaging	Het
Sub1	A	T	15: 11,991,130 (GRCm39)	V37E	possibly damaging	Het
Sult2a6	T	C	7: 13,959,814 (GRCm39)	T240A	probably benign	Het
Tacc2	A	G	7: 130,227,055 (GRCm39)	S1247G	probably benign	Het
Taf4	T	C	2: 179,574,823 (GRCm39)	D594G	probably damaging	Het
Tap1	T	G	17: 34,413,915 (GRCm39)	D643E	probably damaging	Het
Ticam1	T	C	17: 56,578,894 (GRCm39)	N67S	probably benign	Het
Tlr6	A	G	5: 65,110,556 (GRCm39)	F784L	probably damaging	Het
Tmprss15	A	G	16: 78,868,306 (GRCm39)	V202A	probably benign	Het
Trp53bp2	T	C	1: 182,259,193 (GRCm39)	V82A	probably benign	Het
Ube2o	C	T	11: 116,439,661 (GRCm39)	V170I	possibly damaging	Het
Ube2q2l	A	G	6: 136,378,825 (GRCm39)	S2P	possibly damaging	Het
Vmn1r177	G	A	7: 23,565,573 (GRCm39)	T101I	probably benign	Het
Vmn2r68	A	T	7: 84,883,867 (GRCm39)	Y79*	probably null	Het
Wdr35	A	C	12: 9,035,994 (GRCm39)	Y255S	probably benign	Het
Zfp507	A	T	7: 35,502,052 (GRCm39)		probably benign	Het
Zfp688	G	A	7: 127,018,409 (GRCm39)	R239C	probably damaging	Het
Zfp74	T	A	7: 29,635,470 (GRCm39)		probably null	Het
Zfp932	A	G	5: 110,157,069 (GRCm39)	N223D	possibly damaging	Het

Other mutations in Dnah10

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dnah10	APN	5	124,905,667 (GRCm39)	missense	probably damaging	1.00
IGL00089:Dnah10	APN	5	124,823,680 (GRCm39)	missense	probably benign	0.01
IGL00471:Dnah10	APN	5	124,871,405 (GRCm39)	missense	probably damaging	1.00
IGL01336:Dnah10	APN	5	124,852,576 (GRCm39)	missense	probably damaging	1.00
IGL01339:Dnah10	APN	5	124,854,276 (GRCm39)	missense	probably damaging	1.00
IGL01372:Dnah10	APN	5	124,856,218 (GRCm39)	missense	probably damaging	1.00
IGL01572:Dnah10	APN	5	124,861,010 (GRCm39)	missense	probably damaging	1.00
IGL01634:Dnah10	APN	5	124,898,405 (GRCm39)	missense	probably damaging	0.98
IGL01649:Dnah10	APN	5	124,809,553 (GRCm39)	missense	probably damaging	0.97
IGL01676:Dnah10	APN	5	124,880,392 (GRCm39)	missense	possibly damaging	0.65
IGL01729:Dnah10	APN	5	124,864,529 (GRCm39)	missense	probably benign	0.10
IGL01757:Dnah10	APN	5	124,845,991 (GRCm39)	missense	probably benign	0.37
IGL01759:Dnah10	APN	5	124,832,850 (GRCm39)	missense	probably benign
IGL01767:Dnah10	APN	5	124,820,801 (GRCm39)	splice site	probably benign
IGL01769:Dnah10	APN	5	124,842,008 (GRCm39)	missense	possibly damaging	0.63
IGL01805:Dnah10	APN	5	124,860,985 (GRCm39)	missense	probably damaging	1.00
IGL02090:Dnah10	APN	5	124,866,876 (GRCm39)	missense	probably damaging	1.00
IGL02162:Dnah10	APN	5	124,881,810 (GRCm39)	missense	probably damaging	1.00
IGL02312:Dnah10	APN	5	124,896,430 (GRCm39)	missense	probably damaging	1.00
IGL02347:Dnah10	APN	5	124,910,487 (GRCm39)	critical splice acceptor site	probably null
IGL02378:Dnah10	APN	5	124,850,131 (GRCm39)	missense	probably damaging	1.00
IGL02440:Dnah10	APN	5	124,850,883 (GRCm39)	missense	probably damaging	1.00
IGL02457:Dnah10	APN	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
IGL02487:Dnah10	APN	5	124,870,916 (GRCm39)	missense	possibly damaging	0.90
IGL02502:Dnah10	APN	5	124,898,351 (GRCm39)	missense	probably damaging	1.00
IGL02516:Dnah10	APN	5	124,864,395 (GRCm39)	missense	probably damaging	1.00
IGL02544:Dnah10	APN	5	124,876,069 (GRCm39)	missense	probably benign	0.26
IGL02709:Dnah10	APN	5	124,850,809 (GRCm39)	nonsense	probably null
IGL02740:Dnah10	APN	5	124,903,927 (GRCm39)	splice site	probably benign
IGL02746:Dnah10	APN	5	124,807,150 (GRCm39)	missense	possibly damaging	0.55
IGL02803:Dnah10	APN	5	124,875,078 (GRCm39)	missense	probably damaging	0.99
IGL02900:Dnah10	APN	5	124,878,886 (GRCm39)	missense	probably damaging	1.00
IGL02957:Dnah10	APN	5	124,840,197 (GRCm39)	missense	probably benign	0.07
IGL03076:Dnah10	APN	5	124,807,226 (GRCm39)	critical splice donor site	probably null
IGL03109:Dnah10	APN	5	124,841,950 (GRCm39)	missense	probably benign	0.10
IGL03181:Dnah10	APN	5	124,825,521 (GRCm39)	missense	probably damaging	0.99
IGL03185:Dnah10	APN	5	124,894,707 (GRCm39)	missense	probably damaging	1.00
IGL03199:Dnah10	APN	5	124,894,761 (GRCm39)	missense	probably benign	0.00
IGL03328:Dnah10	APN	5	124,831,354 (GRCm39)	missense	probably benign	0.06
frosty	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
H8562:Dnah10	UTSW	5	124,906,593 (GRCm39)	missense	probably damaging	1.00
I2288:Dnah10	UTSW	5	124,807,164 (GRCm39)	missense	probably benign
P0019:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
P0037:Dnah10	UTSW	5	124,895,056 (GRCm39)	nonsense	probably null
PIT4366001:Dnah10	UTSW	5	124,852,588 (GRCm39)	missense	possibly damaging	0.95
R0004:Dnah10	UTSW	5	124,803,966 (GRCm39)	missense	probably benign
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0032:Dnah10	UTSW	5	124,877,955 (GRCm39)	missense	possibly damaging	0.94
R0050:Dnah10	UTSW	5	124,907,808 (GRCm39)	missense	probably benign	0.00
R0066:Dnah10	UTSW	5	124,840,140 (GRCm39)	missense	probably benign	0.01
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0164:Dnah10	UTSW	5	124,860,898 (GRCm39)	missense	probably damaging	1.00
R0196:Dnah10	UTSW	5	124,911,139 (GRCm39)	missense	possibly damaging	0.80
R0312:Dnah10	UTSW	5	124,873,433 (GRCm39)	splice site	probably benign
R0321:Dnah10	UTSW	5	124,900,416 (GRCm39)	missense	probably benign	0.29
R0410:Dnah10	UTSW	5	124,832,799 (GRCm39)	missense	probably benign
R0480:Dnah10	UTSW	5	124,885,915 (GRCm39)	missense	probably damaging	1.00
R0531:Dnah10	UTSW	5	124,889,787 (GRCm39)	critical splice donor site	probably null
R0533:Dnah10	UTSW	5	124,852,314 (GRCm39)	splice site	probably null
R0599:Dnah10	UTSW	5	124,878,017 (GRCm39)	missense	probably damaging	1.00
R0686:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0688:Dnah10	UTSW	5	124,824,782 (GRCm39)	missense	possibly damaging	0.95
R0780:Dnah10	UTSW	5	124,827,876 (GRCm39)	missense	possibly damaging	0.87
R0968:Dnah10	UTSW	5	124,906,641 (GRCm39)	missense	probably damaging	0.99
R0989:Dnah10	UTSW	5	124,875,002 (GRCm39)	missense	probably benign	0.00
R1203:Dnah10	UTSW	5	124,837,078 (GRCm39)	splice site	probably null
R1248:Dnah10	UTSW	5	124,832,887 (GRCm39)	splice site	probably benign
R1366:Dnah10	UTSW	5	124,830,390 (GRCm39)	missense	probably benign	0.41
R1434:Dnah10	UTSW	5	124,852,050 (GRCm39)	missense	probably benign	0.03
R1436:Dnah10	UTSW	5	124,839,285 (GRCm39)	missense	probably benign	0.00
R1438:Dnah10	UTSW	5	124,876,009 (GRCm39)	missense	probably benign	0.25
R1446:Dnah10	UTSW	5	124,866,860 (GRCm39)	missense	probably damaging	1.00
R1459:Dnah10	UTSW	5	124,820,750 (GRCm39)	missense	possibly damaging	0.90
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1466:Dnah10	UTSW	5	124,840,160 (GRCm39)	missense	probably benign
R1479:Dnah10	UTSW	5	124,854,953 (GRCm39)	missense	possibly damaging	0.71
R1505:Dnah10	UTSW	5	124,831,303 (GRCm39)	missense	possibly damaging	0.82
R1519:Dnah10	UTSW	5	124,838,016 (GRCm39)	missense	probably damaging	0.98
R1565:Dnah10	UTSW	5	124,906,678 (GRCm39)	missense	probably damaging	1.00
R1668:Dnah10	UTSW	5	124,842,626 (GRCm39)	missense	probably benign	0.00
R1709:Dnah10	UTSW	5	124,837,155 (GRCm39)	missense	probably damaging	0.99
R1740:Dnah10	UTSW	5	124,850,254 (GRCm39)	splice site	probably null
R1828:Dnah10	UTSW	5	124,838,343 (GRCm39)	missense	probably benign	0.00
R1854:Dnah10	UTSW	5	124,881,753 (GRCm39)	missense	probably damaging	0.99
R1865:Dnah10	UTSW	5	124,909,590 (GRCm39)	splice site	probably null
R1895:Dnah10	UTSW	5	124,835,494 (GRCm39)	missense	probably benign	0.00
R1906:Dnah10	UTSW	5	124,878,048 (GRCm39)	missense	probably damaging	1.00
R1953:Dnah10	UTSW	5	124,859,332 (GRCm39)	missense	probably benign	0.00
R1965:Dnah10	UTSW	5	124,852,267 (GRCm39)	missense	probably damaging	1.00
R2002:Dnah10	UTSW	5	124,911,052 (GRCm39)	missense	probably damaging	1.00
R2006:Dnah10	UTSW	5	124,906,651 (GRCm39)	missense	possibly damaging	0.58
R2037:Dnah10	UTSW	5	124,823,768 (GRCm39)	missense	probably benign	0.30
R2046:Dnah10	UTSW	5	124,873,405 (GRCm39)	missense	probably benign	0.25
R2074:Dnah10	UTSW	5	124,891,738 (GRCm39)	missense	probably damaging	1.00
R2081:Dnah10	UTSW	5	124,852,045 (GRCm39)	missense	possibly damaging	0.88
R2257:Dnah10	UTSW	5	124,838,301 (GRCm39)	missense	probably damaging	1.00
R2272:Dnah10	UTSW	5	124,808,530 (GRCm39)	missense	probably benign	0.00
R2293:Dnah10	UTSW	5	124,896,285 (GRCm39)	missense	probably damaging	0.97
R2323:Dnah10	UTSW	5	124,819,064 (GRCm39)	missense	probably damaging	1.00
R2435:Dnah10	UTSW	5	124,839,929 (GRCm39)	critical splice donor site	probably null
R2571:Dnah10	UTSW	5	124,852,542 (GRCm39)	missense	probably damaging	1.00
R2898:Dnah10	UTSW	5	124,894,734 (GRCm39)	missense	probably damaging	1.00
R2937:Dnah10	UTSW	5	124,896,476 (GRCm39)	critical splice donor site	probably null
R3439:Dnah10	UTSW	5	124,873,322 (GRCm39)	missense	possibly damaging	0.91
R3548:Dnah10	UTSW	5	124,824,694 (GRCm39)	missense	possibly damaging	0.50
R3881:Dnah10	UTSW	5	124,850,095 (GRCm39)	missense	probably benign	0.37
R4015:Dnah10	UTSW	5	124,854,990 (GRCm39)	missense	probably benign	0.25
R4261:Dnah10	UTSW	5	124,807,201 (GRCm39)	missense	possibly damaging	0.95
R4277:Dnah10	UTSW	5	124,809,394 (GRCm39)	missense	probably benign	0.28
R4299:Dnah10	UTSW	5	124,896,989 (GRCm39)	missense	probably damaging	1.00
R4613:Dnah10	UTSW	5	124,839,933 (GRCm39)	splice site	probably null
R4651:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4652:Dnah10	UTSW	5	124,806,207 (GRCm39)	missense	probably benign	0.20
R4664:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4665:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4666:Dnah10	UTSW	5	124,905,536 (GRCm39)	missense	possibly damaging	0.95
R4691:Dnah10	UTSW	5	124,852,581 (GRCm39)	missense	probably damaging	1.00
R4755:Dnah10	UTSW	5	124,824,809 (GRCm39)	missense	probably benign	0.01
R4806:Dnah10	UTSW	5	124,896,408 (GRCm39)	missense	probably damaging	1.00
R4839:Dnah10	UTSW	5	124,850,196 (GRCm39)	missense	probably damaging	1.00
R4903:Dnah10	UTSW	5	124,894,812 (GRCm39)	missense	probably damaging	1.00
R5018:Dnah10	UTSW	5	124,839,260 (GRCm39)	missense	possibly damaging	0.79
R5101:Dnah10	UTSW	5	124,909,577 (GRCm39)	missense	possibly damaging	0.51
R5105:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5119:Dnah10	UTSW	5	124,856,322 (GRCm39)	missense	probably damaging	1.00
R5139:Dnah10	UTSW	5	124,876,024 (GRCm39)	missense	probably damaging	0.99
R5242:Dnah10	UTSW	5	124,864,484 (GRCm39)	missense	probably benign	0.00
R5262:Dnah10	UTSW	5	124,862,220 (GRCm39)	missense	probably damaging	1.00
R5277:Dnah10	UTSW	5	124,905,201 (GRCm39)	missense	probably damaging	1.00
R5293:Dnah10	UTSW	5	124,868,851 (GRCm39)	missense	probably benign	0.01
R5322:Dnah10	UTSW	5	124,850,630 (GRCm39)	missense	probably damaging	1.00
R5371:Dnah10	UTSW	5	124,820,693 (GRCm39)	missense	probably benign	0.16
R5468:Dnah10	UTSW	5	124,907,557 (GRCm39)	missense	probably damaging	1.00
R5470:Dnah10	UTSW	5	124,830,232 (GRCm39)	missense	probably benign
R5587:Dnah10	UTSW	5	124,870,977 (GRCm39)	missense	probably benign	0.10
R5724:Dnah10	UTSW	5	124,819,090 (GRCm39)	missense	probably benign	0.27
R5797:Dnah10	UTSW	5	124,898,450 (GRCm39)	missense	probably benign	0.00
R5812:Dnah10	UTSW	5	124,824,810 (GRCm39)	missense	probably benign	0.01
R5846:Dnah10	UTSW	5	124,900,437 (GRCm39)	missense	possibly damaging	0.80
R5930:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R5961:Dnah10	UTSW	5	124,888,546 (GRCm39)	missense	probably benign	0.01
R5970:Dnah10	UTSW	5	124,885,793 (GRCm39)	missense	probably benign
R6021:Dnah10	UTSW	5	124,814,048 (GRCm39)	missense	probably damaging	1.00
R6043:Dnah10	UTSW	5	124,878,924 (GRCm39)	missense	probably damaging	1.00
R6073:Dnah10	UTSW	5	124,896,274 (GRCm39)	missense	probably benign	0.09
R6080:Dnah10	UTSW	5	124,882,961 (GRCm39)	missense	possibly damaging	0.71
R6093:Dnah10	UTSW	5	124,830,238 (GRCm39)	missense	probably benign	0.18
R6155:Dnah10	UTSW	5	124,862,239 (GRCm39)	missense	probably damaging	1.00
R6155:Dnah10	UTSW	5	124,847,663 (GRCm39)	missense	probably damaging	1.00
R6162:Dnah10	UTSW	5	124,900,382 (GRCm39)	missense	probably benign	0.02
R6238:Dnah10	UTSW	5	124,820,743 (GRCm39)	missense	probably damaging	0.97
R6248:Dnah10	UTSW	5	124,871,283 (GRCm39)	splice site	probably null
R6275:Dnah10	UTSW	5	124,862,248 (GRCm39)	missense	probably damaging	1.00
R6297:Dnah10	UTSW	5	124,852,144 (GRCm39)	missense	possibly damaging	0.55
R6388:Dnah10	UTSW	5	124,906,710 (GRCm39)	missense	probably benign	0.00
R6458:Dnah10	UTSW	5	124,886,333 (GRCm39)	missense	probably damaging	1.00
R6504:Dnah10	UTSW	5	124,839,846 (GRCm39)	missense	possibly damaging	0.50
R6518:Dnah10	UTSW	5	124,835,419 (GRCm39)	missense	probably damaging	0.99
R6627:Dnah10	UTSW	5	124,907,097 (GRCm39)	missense	probably damaging	1.00
R6701:Dnah10	UTSW	5	124,837,223 (GRCm39)	missense	probably benign	0.45
R6702:Dnah10	UTSW	5	124,882,869 (GRCm39)	missense	probably damaging	1.00
R6745:Dnah10	UTSW	5	124,885,876 (GRCm39)	missense	probably damaging	1.00
R6784:Dnah10	UTSW	5	124,854,890 (GRCm39)	missense	probably damaging	0.99
R6807:Dnah10	UTSW	5	124,867,064 (GRCm39)	splice site	probably null
R6932:Dnah10	UTSW	5	124,898,514 (GRCm39)	missense	possibly damaging	0.75
R7007:Dnah10	UTSW	5	124,864,490 (GRCm39)	missense	probably damaging	1.00
R7091:Dnah10	UTSW	5	124,893,206 (GRCm39)	missense	probably benign	0.37
R7138:Dnah10	UTSW	5	124,900,009 (GRCm39)	missense	probably damaging	1.00
R7144:Dnah10	UTSW	5	124,900,006 (GRCm39)	missense	probably damaging	0.98
R7231:Dnah10	UTSW	5	124,890,892 (GRCm39)	missense	probably benign	0.19
R7278:Dnah10	UTSW	5	124,868,855 (GRCm39)	critical splice donor site	probably null
R7284:Dnah10	UTSW	5	124,909,662 (GRCm39)	missense	probably benign	0.37
R7322:Dnah10	UTSW	5	124,898,333 (GRCm39)	missense	probably benign	0.08
R7523:Dnah10	UTSW	5	124,824,803 (GRCm39)	missense	probably damaging	0.97
R7565:Dnah10	UTSW	5	124,876,095 (GRCm39)	missense	probably damaging	1.00
R7593:Dnah10	UTSW	5	124,823,608 (GRCm39)	missense	probably benign	0.21
R7606:Dnah10	UTSW	5	124,894,776 (GRCm39)	missense	probably benign	0.00
R7835:Dnah10	UTSW	5	124,854,298 (GRCm39)	missense	probably damaging	1.00
R7898:Dnah10	UTSW	5	124,859,425 (GRCm39)	missense	probably damaging	1.00
R7972:Dnah10	UTSW	5	124,803,949 (GRCm39)	missense	probably benign
R7999:Dnah10	UTSW	5	124,802,322 (GRCm39)	missense	probably benign	0.06
R8017:Dnah10	UTSW	5	124,877,949 (GRCm39)	missense	probably benign	0.03
R8032:Dnah10	UTSW	5	124,823,676 (GRCm39)	missense	probably damaging	0.98
R8052:Dnah10	UTSW	5	124,905,575 (GRCm39)	missense	probably benign	0.00
R8088:Dnah10	UTSW	5	124,831,330 (GRCm39)	missense	probably benign	0.00
R8169:Dnah10	UTSW	5	124,877,946 (GRCm39)	missense	probably damaging	1.00
R8178:Dnah10	UTSW	5	124,832,790 (GRCm39)	missense	probably benign	0.11
R8200:Dnah10	UTSW	5	124,905,524 (GRCm39)	missense	probably damaging	1.00
R8210:Dnah10	UTSW	5	124,827,858 (GRCm39)	missense	probably benign	0.29
R8294:Dnah10	UTSW	5	124,859,410 (GRCm39)	missense	probably damaging	1.00
R8338:Dnah10	UTSW	5	124,909,566 (GRCm39)	missense	probably damaging	1.00
R8404:Dnah10	UTSW	5	124,850,606 (GRCm39)	missense	probably damaging	1.00
R8469:Dnah10	UTSW	5	124,813,895 (GRCm39)	missense	probably damaging	1.00
R8537:Dnah10	UTSW	5	124,893,164 (GRCm39)	missense	probably damaging	0.97
R8701:Dnah10	UTSW	5	124,803,911 (GRCm39)	missense	probably benign	0.00
R8723:Dnah10	UTSW	5	124,891,685 (GRCm39)	missense	probably damaging	0.99
R8770:Dnah10	UTSW	5	124,852,410 (GRCm39)	missense	possibly damaging	0.94
R8838:Dnah10	UTSW	5	124,842,614 (GRCm39)	missense	probably benign	0.09
R8879:Dnah10	UTSW	5	124,895,181 (GRCm39)	missense	probably damaging	1.00
R8928:Dnah10	UTSW	5	124,866,828 (GRCm39)	missense	probably damaging	0.98
R8932:Dnah10	UTSW	5	124,878,015 (GRCm39)	missense	possibly damaging	0.96
R8945:Dnah10	UTSW	5	124,891,006 (GRCm39)	missense	probably damaging	0.99
R8990:Dnah10	UTSW	5	124,814,057 (GRCm39)	missense
R9001:Dnah10	UTSW	5	124,852,515 (GRCm39)	missense	probably damaging	1.00
R9006:Dnah10	UTSW	5	124,820,783 (GRCm39)	missense	probably benign	0.23
R9060:Dnah10	UTSW	5	124,905,141 (GRCm39)	missense	probably damaging	1.00
R9085:Dnah10	UTSW	5	124,839,237 (GRCm39)	missense
R9133:Dnah10	UTSW	5	124,859,423 (GRCm39)	missense	probably damaging	1.00
R9155:Dnah10	UTSW	5	124,907,475 (GRCm39)	missense	probably damaging	0.99
R9220:Dnah10	UTSW	5	124,871,437 (GRCm39)	missense	probably benign	0.05
R9234:Dnah10	UTSW	5	124,818,989 (GRCm39)	missense	possibly damaging	0.94
R9264:Dnah10	UTSW	5	124,813,900 (GRCm39)	missense	probably damaging	1.00
R9266:Dnah10	UTSW	5	124,845,990 (GRCm39)	missense	probably benign	0.00
R9386:Dnah10	UTSW	5	124,871,507 (GRCm39)	critical splice donor site	probably null
R9446:Dnah10	UTSW	5	124,823,677 (GRCm39)	missense	probably damaging	1.00
R9484:Dnah10	UTSW	5	124,900,508 (GRCm39)	missense	probably damaging	1.00
R9594:Dnah10	UTSW	5	124,907,107 (GRCm39)	missense	probably damaging	1.00
R9691:Dnah10	UTSW	5	124,852,249 (GRCm39)	missense	probably damaging	0.98
RF015:Dnah10	UTSW	5	124,895,141 (GRCm39)	missense	probably damaging	1.00
RF021:Dnah10	UTSW	5	124,854,971 (GRCm39)	missense	probably damaging	1.00
T0975:Dnah10	UTSW	5	124,840,130 (GRCm39)	missense	probably benign
U24488:Dnah10	UTSW	5	124,891,044 (GRCm39)	missense	probably damaging	1.00
X0017:Dnah10	UTSW	5	124,842,761 (GRCm39)	missense	probably benign	0.22
Z1176:Dnah10	UTSW	5	124,852,419 (GRCm39)	missense	probably benign	0.11
Z1177:Dnah10	UTSW	5	124,819,019 (GRCm39)	missense	probably damaging	1.00
Z1177:Dnah10	UTSW	5	124,895,052 (GRCm39)	critical splice acceptor site	probably null
Z1177:Dnah10	UTSW	5	124,824,683 (GRCm39)	missense	possibly damaging	0.64

Predicted Primers

PCR Primer
(F):5'- AATGTCCTGATGGAAGATGCTGG -3'
(R):5'- GTGTATGCTTGCACACCTGC -3'

Sequencing Primer
(F):5'- CACTGGGGGACATGGTACTATC -3'
(R):5'- ACCTGCGTGCACGTGTTTG -3'

Posted On

2014-06-30