Incidental Mutation 'R0403:Ddx60'
| ID |
212536 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| Synonyms |
|
| MMRRC Submission |
038608-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.145)
|
| Stock # |
R0403 (G1)
|
| Quality Score |
65 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
61928087-62038244 bp(+) (GRCm38) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 61994541 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070631
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093485
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.0%
- 3x: 96.8%
- 10x: 93.2%
- 20x: 83.7%
|
| Validation Efficiency |
97% (110/113) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ace |
A |
G |
11: 105,973,880 |
|
probably null |
Het |
| Adgrg3 |
C |
T |
8: 95,036,922 |
L284F |
probably benign |
Het |
| Alkbh8 |
T |
A |
9: 3,385,469 |
V587E |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,818,839 |
C244S |
probably damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,821,396 |
M590K |
probably benign |
Het |
| Arhgap15 |
C |
T |
2: 44,063,766 |
T168I |
probably damaging |
Het |
| Arntl2 |
T |
A |
6: 146,822,655 |
H348Q |
probably damaging |
Het |
| Atp8b1 |
A |
G |
18: 64,540,310 |
V997A |
probably damaging |
Het |
| Atrn |
G |
A |
2: 130,906,859 |
C100Y |
probably damaging |
Het |
| Baiap2l2 |
C |
A |
15: 79,271,216 |
A151S |
probably benign |
Het |
| Baz2b |
A |
T |
2: 59,969,377 |
D199E |
possibly damaging |
Het |
| Cblb |
A |
G |
16: 52,152,626 |
D440G |
probably benign |
Het |
| Cdon |
T |
C |
9: 35,473,500 |
V694A |
probably benign |
Het |
| Cep250 |
A |
T |
2: 155,992,349 |
R2065W |
probably damaging |
Het |
| Ces2b |
G |
T |
8: 104,833,945 |
A131S |
probably damaging |
Het |
| Chrna9 |
A |
T |
5: 65,967,892 |
T59S |
possibly damaging |
Het |
| Cog3 |
T |
A |
14: 75,742,327 |
|
probably benign |
Het |
| Cpa1 |
G |
A |
6: 30,641,857 |
V227I |
probably benign |
Het |
| Cyp3a25 |
A |
T |
5: 145,998,513 |
C98S |
probably damaging |
Het |
| D8Ertd738e |
C |
T |
8: 84,249,601 |
|
probably null |
Het |
| Dhx16 |
T |
C |
17: 35,883,050 |
|
probably null |
Het |
| Dnah9 |
T |
A |
11: 66,084,789 |
Q1478L |
possibly damaging |
Het |
| Dock10 |
T |
C |
1: 80,524,070 |
Y1434C |
possibly damaging |
Het |
| Enpp3 |
T |
A |
10: 24,804,436 |
D325V |
probably damaging |
Het |
| Entpd6 |
C |
A |
2: 150,760,170 |
T194K |
possibly damaging |
Het |
| Fam208b |
A |
T |
13: 3,582,052 |
Y816* |
probably null |
Het |
| Fat2 |
A |
T |
11: 55,270,349 |
V3185E |
probably benign |
Het |
| Flrt1 |
A |
G |
19: 7,095,919 |
L421P |
probably benign |
Het |
| Fmn2 |
A |
T |
1: 174,694,278 |
Q1292L |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,753,723 |
D1459G |
probably damaging |
Het |
| Fndc1 |
T |
C |
17: 7,775,588 |
|
probably null |
Het |
| Fzr1 |
A |
G |
10: 81,369,368 |
S265P |
possibly damaging |
Het |
| Gm13119 |
A |
G |
4: 144,362,646 |
N178S |
probably benign |
Het |
| Gm14085 |
T |
C |
2: 122,521,854 |
L364S |
probably damaging |
Het |
| Gpr142 |
G |
A |
11: 114,806,029 |
V134M |
probably damaging |
Het |
| Grid2ip |
G |
T |
5: 143,357,620 |
V24L |
possibly damaging |
Het |
| Herc2 |
G |
A |
7: 56,159,417 |
R2555H |
probably damaging |
Het |
| Hpdl |
A |
T |
4: 116,820,479 |
Y262N |
possibly damaging |
Het |
| Htr3a |
A |
G |
9: 48,908,659 |
V57A |
probably damaging |
Het |
| Igfbp7 |
T |
C |
5: 77,355,591 |
I186V |
probably benign |
Het |
| Itga2b |
C |
T |
11: 102,467,326 |
|
probably null |
Het |
| Itgae |
A |
C |
11: 73,123,183 |
D736A |
possibly damaging |
Het |
| Itpkc |
T |
A |
7: 27,208,345 |
M645L |
probably benign |
Het |
| Jchain |
T |
C |
5: 88,521,378 |
R139G |
probably benign |
Het |
| Kif13a |
A |
G |
13: 46,791,401 |
V908A |
probably damaging |
Het |
| Kif1b |
T |
A |
4: 149,181,967 |
K389* |
probably null |
Het |
| Klhl12 |
T |
C |
1: 134,485,856 |
Y360H |
possibly damaging |
Het |
| Knop1 |
G |
A |
7: 118,853,053 |
R148W |
probably damaging |
Het |
| Lpar1 |
T |
A |
4: 58,487,191 |
N27Y |
probably damaging |
Het |
| Lpar2 |
T |
A |
8: 69,824,152 |
V197D |
probably damaging |
Het |
| Lrrc74a |
A |
G |
12: 86,740,979 |
N128S |
probably damaging |
Het |
| Lum |
G |
T |
10: 97,572,043 |
V337F |
probably benign |
Het |
| Mag |
T |
C |
7: 30,906,980 |
D344G |
probably damaging |
Het |
| Maip1 |
G |
A |
1: 57,407,196 |
A142T |
probably benign |
Het |
| Mlh3 |
A |
G |
12: 85,268,968 |
V148A |
possibly damaging |
Het |
| Nav3 |
A |
G |
10: 109,767,103 |
V1195A |
probably damaging |
Het |
| Ncor2 |
A |
G |
5: 125,033,337 |
S868P |
possibly damaging |
Het |
| Nek1 |
A |
G |
8: 61,106,855 |
E907G |
probably damaging |
Het |
| Nfam1 |
G |
A |
15: 83,016,379 |
T134I |
probably benign |
Het |
| Nr0b2 |
T |
C |
4: 133,553,759 |
V112A |
probably damaging |
Het |
| Nrp1 |
A |
G |
8: 128,457,969 |
N365S |
probably damaging |
Het |
| Nrsn2 |
T |
C |
2: 152,369,790 |
Y107C |
probably damaging |
Het |
| Ntng1 |
G |
A |
3: 109,934,611 |
A282V |
probably damaging |
Het |
| Nxf1 |
T |
C |
19: 8,765,028 |
I337T |
probably damaging |
Het |
| Obscn |
C |
T |
11: 59,076,540 |
G479D |
probably damaging |
Het |
| Olfr45 |
T |
C |
7: 140,691,309 |
S135P |
possibly damaging |
Het |
| Oprd1 |
T |
A |
4: 132,113,768 |
D293V |
probably benign |
Het |
| P3h2 |
T |
G |
16: 25,969,950 |
N586H |
possibly damaging |
Het |
| Pcid2 |
T |
C |
8: 13,085,367 |
Y214C |
probably damaging |
Het |
| Pkd1l3 |
C |
G |
8: 109,623,649 |
D375E |
possibly damaging |
Het |
| Pkd1l3 |
G |
A |
8: 109,623,663 |
S380N |
probably benign |
Het |
| Ppic |
C |
A |
18: 53,411,071 |
G81W |
probably damaging |
Het |
| Ppp2r1a |
C |
A |
17: 20,957,041 |
P246T |
probably damaging |
Het |
| Ppp4r4 |
T |
G |
12: 103,584,102 |
S46A |
probably benign |
Het |
| Prkce |
A |
G |
17: 86,168,653 |
T21A |
probably damaging |
Het |
| Prkg2 |
T |
C |
5: 98,994,645 |
E210G |
possibly damaging |
Het |
| Prss35 |
A |
G |
9: 86,756,037 |
M287V |
probably damaging |
Het |
| Psd |
G |
A |
19: 46,320,972 |
|
probably benign |
Het |
| Ptch2 |
A |
T |
4: 117,110,839 |
K843* |
probably null |
Het |
| Rab44 |
C |
A |
17: 29,145,261 |
T603K |
probably damaging |
Het |
| Rasal3 |
T |
A |
17: 32,392,790 |
|
probably null |
Het |
| Rbbp6 |
A |
G |
7: 122,992,296 |
T526A |
probably damaging |
Het |
| Ros1 |
A |
T |
10: 52,143,438 |
|
probably benign |
Het |
| Sec24b |
T |
A |
3: 129,989,676 |
L1104F |
possibly damaging |
Het |
| Sec24b |
A |
G |
3: 129,999,534 |
S685P |
probably damaging |
Het |
| Sema6a |
G |
A |
18: 47,290,045 |
|
probably null |
Het |
| Setmar |
A |
T |
6: 108,075,962 |
H139L |
probably benign |
Het |
| Slc4a7 |
T |
C |
14: 14,766,808 |
V710A |
probably benign |
Het |
| Smarcc1 |
T |
A |
9: 110,237,808 |
|
probably null |
Het |
| Smchd1 |
G |
A |
17: 71,394,902 |
L1032F |
probably damaging |
Het |
| Speg |
T |
C |
1: 75,430,784 |
|
probably benign |
Het |
| Tcea1 |
C |
G |
1: 4,889,503 |
R134G |
probably benign |
Het |
| Tchhl1 |
C |
T |
3: 93,471,029 |
Q347* |
probably null |
Het |
| Tecrl |
A |
T |
5: 83,354,758 |
|
probably benign |
Het |
| Tepsin |
T |
C |
11: 120,093,682 |
|
probably benign |
Het |
| Tmem40 |
G |
A |
6: 115,733,985 |
|
probably benign |
Het |
| Tpr |
G |
A |
1: 150,407,414 |
|
probably benign |
Het |
| Ttll12 |
A |
T |
15: 83,580,658 |
|
probably benign |
Het |
| Ttn |
T |
A |
2: 76,909,608 |
D3529V |
probably benign |
Het |
| Usp34 |
T |
A |
11: 23,333,838 |
H177Q |
possibly damaging |
Het |
| Vsig10 |
T |
A |
5: 117,338,461 |
S327T |
probably benign |
Het |
| Zbtb4 |
T |
A |
11: 69,777,639 |
M396K |
probably damaging |
Het |
| Zfp352 |
C |
T |
4: 90,225,009 |
T462I |
possibly damaging |
Het |
| Zfp385b |
T |
C |
2: 77,476,845 |
M145V |
probably damaging |
Het |
| Zfp780b |
C |
A |
7: 27,971,689 |
V65F |
possibly damaging |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
61,958,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
61,987,431 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
61,969,583 (GRCm38) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
61,942,514 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
61,982,526 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
61,963,740 (GRCm38) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
61,983,865 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,017,823 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,000,709 (GRCm38) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,017,247 (GRCm38) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
61,975,832 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
61,958,642 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,024,951 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
61,942,436 (GRCm38) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
61,984,115 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
61,988,132 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
61,979,341 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
61,956,122 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
61,988,083 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,012,449 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
61,977,882 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
61,958,113 (GRCm38) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
61,972,254 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
61,942,293 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,033,493 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
61,983,855 (GRCm38) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,017,749 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R0479:Ddx60
|
UTSW |
8 |
61,969,657 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,017,794 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
61,987,361 (GRCm38) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
61,942,544 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
61,958,159 (GRCm38) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
61,974,176 (GRCm38) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
61,969,553 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1964:Ddx60
|
UTSW |
8 |
61,948,869 (GRCm38) |
missense |
probably benign |
0.10 |
|
R1970:Ddx60
|
UTSW |
8 |
61,972,206 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
61,940,645 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,017,200 (GRCm38) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
61,956,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
61,958,063 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,037,091 (GRCm38) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,012,436 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,037,088 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
61,956,144 (GRCm38) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
61,972,220 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
61,994,393 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
61,948,978 (GRCm38) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
61,942,461 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
61,987,421 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,023,261 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,037,067 (GRCm38) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,012,424 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,021,314 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
61,979,338 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
61,945,906 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
61,974,188 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
61,984,158 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,010,002 (GRCm38) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
61,950,451 (GRCm38) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
61,958,057 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,000,578 (GRCm38) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
61,948,921 (GRCm38) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
61,948,897 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,012,388 (GRCm38) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
61,963,722 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
61,956,121 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
61,940,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,021,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,000,582 (GRCm38) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,023,241 (GRCm38) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
61,945,940 (GRCm38) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
61,950,578 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
61,983,905 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
61,998,681 (GRCm38) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
61,977,950 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
61,956,239 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,037,070 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
61,983,890 (GRCm38) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,000,689 (GRCm38) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,037,069 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
61,988,108 (GRCm38) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
61,958,578 (GRCm38) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
61,940,674 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
61,975,792 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
61,977,890 (GRCm38) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
61,954,535 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
61,983,911 (GRCm38) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,017,171 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,017,250 (GRCm38) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
61,977,968 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
61,940,108 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,000,597 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
61,998,769 (GRCm38) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
61,942,635 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
61,974,171 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
61,956,243 (GRCm38) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
61,974,150 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
61,958,606 (GRCm38) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
61,945,956 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
61,940,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,021,309 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
61,994,519 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
61,974,134 (GRCm38) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
61,989,864 (GRCm38) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,017,841 (GRCm38) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
61,977,978 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,009,960 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
61,972,214 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,012,278 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,033,417 (GRCm38) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
61,963,692 (GRCm38) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,000,588 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- acACACAACCAGAACAGAGAGACTGA -3'
(R):5'- GCAGAACTACATGCTGAGAGCAATGA -3'
Sequencing Primer
(F):5'- GAATGTGCTGAAAATGCTTTCG -3'
(R):5'- TGCTGAGAGCAATGAGCTTCC -3'
|
| Posted On |
2014-07-08 |
Incidental Mutation